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Dissertations / Theses on the topic 'Rapid onset of action'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

Becker, Andrea. "Wood frame building response to rapid onset flooding." Thesis, University of British Columbia, 2008. http://hdl.handle.net/2429/2429.

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Floods are considered to be among of the deadliest, costliest and most common natural disasters. Rapid onset, catastrophic floods inundate the shore quickly and manifest as deep water with high velocities. The deep water and high velocities caused by these floods inflict great pressures and forces on the built and natural environments and pose a threat to human safety. Recent disasters such as Hurricane Katrina in the Southern United States and the Sumatra tsunami in the Indian Ocean have revealed that communities at risk require improved preparations for these types of dangerous events. C

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Casper, C. J. "The cellular pathology of Rapid-Onset Dystonia-Parkinsonism." Thesis, University College London (University of London), 2013. http://discovery.ucl.ac.uk/1400116/.

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The dystonias are a common group of movement disorders, which are mechanistically poorly understood. Rapid-onset dystonia-parkinsonism (RDP) is a hereditary movement disorder without neurodegeneration resulting from mutations in the ATP1A3 gene encoding the α3-isoform of the Na+/K+ ATPase. RDP patients are generally asymptomatic until a stressful life event triggers disease onset. Basal Ganglia dysfunction has previously been implicated in RDP aaetiology. To investigate the neuronal pathology in RDP we have generated patient-specific induced pluripotent stem cell (iPS) lines and derived mature

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Marmon, Adam Rubin. "Neuromuscular adaptations associated with the onset of rapid strength gains in the elderly." Access to citation, abstract and download form provided by ProQuest Information and Learning Company; downloadable PDF file 0.47Mb, 81 p, 2005. http://wwwlib.umi.com/dissertations/fullcit/1428180.

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Kaniewski, Connie. "Understanding Flash Drought Spatial Extent, Duration, and Meteorological Drivers." OpenSIUC, 2021. https://opensiuc.lib.siu.edu/theses/2876.

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Drought is conventionally known as a slow-developing natural hazard. In recent years, a subset of drought events characterized by rapid onset has been identified and deemed “flash” droughts. These flash droughts can result in rapid soil drying and rapid vegetation degradation making them damaging to agriculture and the economy, so it is essential to develop reliable early warning systems for flash drought events. This study aims to compare the climatology between flash and non-flash droughts across the Contiguous United States (CONUS) and regionally to identify key differences in the drought t

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Bonicelli, Alice [Verfasser], and A. [Akademischer Betreuer] Cato. "Rapid action of glucocorticoids in mast cells / Alice Bonicelli ; Betreuer: A. Cato." Karlsruhe : KIT-Bibliothek, 2016. http://d-nb.info/1126036706/34.

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Behrendt, Silke, Hans-Ulrich Wittchen, Michael Höfler, Roselind Lieb, and Katja Beesdo. "Transitions from first substance use to substance use disorders in adolescence: Is early onset associated with a rapid escalation?" Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2013. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-110746.

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Background: Early substance use (SU) in adolescence is known to be associated with an elevated risk of developing substance use disorders (SUD); it remains unclear though whether early SU is associated with more rapid transitions to SUD. Objective: To examine the risk and speed of transition from first SU (alcohol, nicotine, cannabis) to SUD as a function of age of first use. Methods: N = 3021 community subjects aged 14–24 years at baseline were followed-up prospectively over 10-years. SU and SUD were assessed using the DSM-IV/M-CIDI. Results: (1) The conditional probability of substance-sp

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Behrendt, Silke, Hans-Ulrich Wittchen, Michael Höfler, Roselind Lieb, and Katja Beesdo. "Transitions from first substance use to substance use disorders in adolescence: Is early onset associated with a rapid escalation?" Technische Universität Dresden, 2009. https://tud.qucosa.de/id/qucosa%3A26833.

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Background: Early substance use (SU) in adolescence is known to be associated with an elevated risk of developing substance use disorders (SUD); it remains unclear though whether early SU is associated with more rapid transitions to SUD. Objective: To examine the risk and speed of transition from first SU (alcohol, nicotine, cannabis) to SUD as a function of age of first use. Methods: N = 3021 community subjects aged 14–24 years at baseline were followed-up prospectively over 10-years. SU and SUD were assessed using the DSM-IV/M-CIDI. Results: (1) The conditional probability of substance-sp

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8

Fang, Kun. "Progression and onset of undercut slope failure observed by surface velocity in physical models subjected to arch action." Kyoto University, 2019. http://hdl.handle.net/2433/242486.

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9

Bohman, William E. "STAFFSIM, an interactive simulation for rapid, real time course of action analysis by U.S. Army Brigade Staffs." Thesis, Monterey, Calif. : Springfield, Va. : Naval Postgraduate School ; Available from National Technical Information Service, 1999. http://handle.dtic.mil/100.2/ADA371071.

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Thesis (M.S. in Modeling, Virtual Environments and Simulation (MOVES))--Naval Postgraduate School, June 1999.<br>"June 1999". Thesis advisor(s): Arnold H. Buss, Bard Mansager. Includes bibliographical references (p. 107-109). Also avaliable online.

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Collis, Lisa Janine. "Rapid hyaluronan uptake is associated with enhanced motility and transformation, implications for an intracellular mode of action." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp01/MQ45877.pdf.

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11

Hanson, Brady Edward. "The Relationship Between Vascular Endothelial Function andPeak Exercise Blood Flow." BYU ScholarsArchive, 2019. https://scholarsarchive.byu.edu/etd/7527.

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Purpose The vascular endothelium is an influential contributor to vasodilation at rest, yet its role during peak exercise is relatively unknown. The purpose of this study is to determine if exercise leg blood flow during dynamic submaximal and maximal exercise is related to resting vascular endothelial function. Methods Nineteen subjects (aged 23 Â± 0.57 yr) completed multiple assessments of vascular endothelial function including passive leg movement (PLM), rapid onset vasodilation, (ROV) and flow-mediated dilation (FMD). Peak muscle blood flow was assessed during single leg knee extension (K

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12

Stolzenberg, Danielle Suzanne. "Dopamine Action in the Nucleus Accumbens and Medial Preoptic Area and the Regulation of the Hormonal Onset of Maternal Behavior in Rats." Thesis, Boston College, 2009. http://hdl.handle.net/2345/758.

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Thesis advisor: Michael Numan<br>Postpartum female rats immediately respond to biological or foster offspring with the display of maternal behavior. In contrast, females that are hysterectomized and ovariectomized on day 15 of pregnancy (15HO) and presented with pups 48 hours later show maternal behavior after 2-3 days of pup exposure. The natural onset of maternal behavior in postpartum females is mediated, in part, by the rise in estradiol just prior to birth. When 15HO rats are administered estradiol benzoate (EB) at the time of HO surgery, 48 hours prior to pup presentation, they show an a

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Chan, Patrick G. "A pharmacodynamic model of the role of 5-HT2A and GABAA receptors in the delay in the onset of action of SSRIS." Scholarly Commons, 2009. https://scholarlycommons.pacific.edu/uop_etds/2396.

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Depression is a common neuropsychiatric illness with a lifetime prevalence of 17% in the United States. The disease can severely impact the daily living and quality of life in patients. The monoamine hypothesis of depression implicates the neurotransmitter serotonin as mediating the pathophysiology. Selective serotonin reuptake inhibitors (SSRIs), a popular and efficacious class of antidepressants, increase serotonin concentrations in the brain. However, full clinical benefit may not be obtained for four to six weeks. This period of waiting for SSRIs to work becomes quite daunting for patients

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Mezmur, Benyam Dawit. "Intercountry adoption in an African context: A legal perspective." Thesis, University of the Western Cape, 2009. http://etd.uwc.ac.za/index.php?module=etd&action=viewtitle&id=gen8Srv25Nme4_6934_1378888793.

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<p>The focus of this research is the experiences of patients with regard to social and health services factors that contribute to delays in seeking treatment for tuberculosis. The goal of this&nbsp<br>research study was to do an explorative study in order to establish the experiences of patients with regard to social and health services factors that contribute to delays in seeking treatment for Tuberculosis. The objectives to meet the goal were an exploration and description of patients&rsquo<br>experiences with regards to social and health service factors contributing to delays in seeking&nbs

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Liebenberg, Nico. "The role of alpha-2A-adrenergic receptor antagonism in therapeutic efficacy and onset of action of antidepressant drugs in a rat model of depression / Nico Liebenberg." Thesis, North-West University, 2006. http://hdl.handle.net/10394/1414.

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16

Kosick, Ruthann. "Using a Pediatric Early Warning Score Algorithm for Activating a Rapid Response Team." ScholarWorks, 2019. https://scholarworks.waldenu.edu/dissertations/7483.

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The nursing culture of an inpatient pediatric unit was resistant to activating pediatric rapid response team (PRRT) alerts despite guidelines for activation. Nurses routinely assessed patients and assigned a pediatric early warning score (PEWS); however, the level of illness severity was not interpreted consistently among nurses and a PEWS action algorithm did not exist to guide nurses' minimal actions based on the PEWS score. Guided by 3 adult learning theories (Knowles, Kolb, and Bandura) and 1 evaluation model (Kirkpatrick), this staff education project sought to educate pediatric nurses on

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Rossouw, Theresa. "The experiences of patients with regard to social and health services factors that contribute to delays in seeking treatment for tuberculosis." Thesis, University of the Western Cape, 2008. http://etd.uwc.ac.za/index.php?module=etd&action=viewtitle&id=gen8Srv25Nme4_2586_1260256819.

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<p>The goal of this research study was to do an explorative study in order to establish the experiences of patients with regard to social and health services factors that contribute to delays in seeking treatment for Tuberculosis.</p>

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18

Rip, Diane. "Sample preparation methods and molecular based detection for the rapid isolation and identification of Listeria monocytogenes in food samples." Thesis, University of the Western Cape, 2006. http://etd.uwc.ac.za/index.php?module=etd&action=viewtitle&id=gen8Srv25Nme4_1346_1255007553.

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<p>Listeria monocytogenes is a Gram-positive bacterium responsible for listeriosis, a food-borne disease, which may result in severe illness and possible death. The importance of L. monocytogenes as a food-borne pathogen has been recognized since the 1980's when a correlation between the cunsumption of contaminated foodstuffs and human listeriosis outbreaks was observed. Listeriosis occurs with the ingestion of contaminated foods. The aim of this study involved developing DNA based methods to aid the food industry for the fast detection of L. monocytogenes in food products. Therefore assays we

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Brazier, Linda Diane. "The effect on perception of pain sensation, distress and incentive spirometry performance when cholecystectomy patients are mobilized at onset, peak or post peak of opioid (meperidine) action." Thesis, University of British Columbia, 1988. http://hdl.handle.net/2429/27329.

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There has been little study of ways to decrease pain generated by painful postoperative exercise. The purpose of this study was to determine the effect of performing painful activities at various times of analgesic action on pain sensation, pain distress and inspiratory capacity of one day postoperative cholecystectomy patients. In addition, the relationship of inspiratory capacity to pain sensation and distress was explored. The theoretical framework for this study was based on Melzack and Wall's Revised Gate Control Theory of Pain. This experimental study used a randomized balanced incomple

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Gao, Xiaoqian. "Environmental Endocrine Disrupting Chemicals and Cardiac Arrhythmogenesis." University of Cincinnati / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1427799826.

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Larsson, Lena. "Har han det bra så har jag det bra : ett aktionsforskningsprojekt där ett närståendestöd planerades i samarbete med närstående till yngre personer med demenssjukdom." Thesis, Kristianstad University College, School of Health and Society, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:hkr:diva-4800.

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<p>Om närstående ska orka leva tillsammans med en yngre demenssjuk partner behöver de erbjudas stöd som är utformat utifrån deras situation och behov. Syftet var att i samarbete med närstående till personer vars demenssjukdom debuterat före 65 års ålder planera ett närståendestöd. Metoden som användes var Participatory Action Research (PAR), en interaktiv forskningsmetod som innefattar reflektion, analys och handling. Fokusgruppssamtal genomfördes med två fokusgrupper vid vardera tre tillfällen. Samtliga deltagare var make eller maka som levde tillsammans med en yngre demenssjuk partner. Studi

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Chiou, Li-Kuei. "The effect that design of the Nucleus Intracochlear Electrode Array and age of onset of hearing loss have on electrically evoked compound action potential growth and spread of excitation functions." Diss., University of Iowa, 2016. https://ir.uiowa.edu/etd/3060.

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The purpose of this study was to investigate how design changes in Cochlear Nucleus cochlear implants (CIs) (CI24M, CI24R, CI24RE and CI422) affected electrode impedance and ECAP measures, and to determine if these design changes affected post-lingually deafened adults and children with congenital hearing loss in a similar way. Results of this study showed that electrode impedance was inversely related to the area of the electrode contacts in the array: lowest for the full-banded CI24M CI and highest for adults who used the CI422 device which has the smallest electrode contacts of all four dev

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Khoza, Kenneth. "Characterisation of the α2A-adrenoceptor antagonism by mirtazapine and its modifying effects on receptor signalling / Kenneth Khoza". Thesis, North-West University, 2004. http://hdl.handle.net/10394/673.

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Mirtazapine is an atypical antidepressant employed clinically for the treatment of major depression. As a multipotent antagonist it acts at α2a-adrenergic receptors (α2a -ARs). serotonin type-2A receptors (5-HT2a-Rs) and histamine type-I receptors (H1-Rs). Its actions at the α2a-AR have been proposed to play a role in its putative earlier onset of action. However, it is not known whether mirtazapine is a neutral antagonist or inverse agonist at α2a- ARs. The current study aimed to determine the mode of α2a-AR antagonism by mirtazapine, as well as to investigate in vitro the modulatory effects

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Shareef, Zeinab. "Ordflöde och läsförmåga hos studenter med och utan dyslexi : En undersökning av FAS, djurflöde och verbflöde." Thesis, Uppsala universitet, Logopedi, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-369667.

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Bakgrund och syfte. Ordflödestest undersöker en persons förmåga att generera så många ord som möjligt under en minut. Orden kan börja på en viss bokstav eller tillhöra en särskild kategori. FAS är ett vanligt ordflödestest där orden som ska genereras börjar på bokstäverna F, A och S. Exempel på kategoriska ordflödestest är djurflöde, som går ut på att säga så många djur som möjligt, samt verbflöde där instruktionen är att säga så många saker man kan göra (handlingar). Forskare har undersökt vilka mentala färdigheter som ligger till grund för ordflödesförmågan, framför allt planerande och regle

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Ruzow, Holland Ann Hope. "Participatory Planning for a Promised Land: Citizen-Led, Comprehensive Land Use Planning in New York’s Adirondack Park." Antioch University / OhioLINK, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=antioch1292545997.

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Худоба, І. С., та I. S. Khudoba. "Адміністративно-правовий статус Корпусу оперативно-раптової дії як спеціального підрозділу Національної поліції : дисертація". Thesis, Харків, 2020. https://youtu.be/1eXxSnPkYAs.

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Худоба, І. С. Адміністративно-правовий статус Корпусу оперативно-раптової дії як спеціального підрозділу Національної поліції : дис. ... д-ра філос.: 081, 08 / Іван Станіславович Худоба; МВС України, Харків. нац. ун-т внутр. справ. - Харків, 2020. - 236 с.<br>У дисертації наведено теоретичне узагальнення та нове вирішення наукового завдання, яке полягає у визначенні сутності, змісту та особливостей адміністративно-правового статусу Корпусу оперативно-раптової дії як спеціального підрозділу Національної поліції та шляхів його вдосконалення з урахуванням вітчизняної практики та зарубіжного досві

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Chang, Chung-Chiao, and 張仲喬. "Development of Sildenafil Microemulsion for Rapid-Onset Nasal Spray." Thesis, 2008. http://ndltd.ncl.edu.tw/handle/74725556409294394262.

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碩士<br>臺北醫學大學<br>藥學研究所<br>96<br>An oleic acid-based microemulsion system with Cremophor EL or Tween series as surfactants, and short-chain alcohol, PEG 600 or PG as cosolvents was developed for rapid-onset intranasal delivery of sildenafil. Phase behavior and solubilization capacity of the microemulsion system were characterized and in vivo nasal absorption of sildenafil from microemulsion formulations was investigated in rabbits. A single isotropic region, which is considered as a microemulsion, was found in the pseudo-ternary phase diagrams developed at various surfactants : cosolvents ratios

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Chou, Po-Yu, and 周柏宇. "Development of Sildenafil for Rapid-Onset Sublingual Drug Delivery System." Thesis, 2010. http://ndltd.ncl.edu.tw/handle/41302586487992477295.

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碩士<br>臺北醫學大學<br>藥學研究所<br>98<br>Oral sildenafil (Viagra®) is the most popular drug to treat erectile dysfunction. However, it should be taken 1 hour before sexual intercourse and lower bioavailability. It is well known that sublingual delivery of drugs offers rapid absorption and high bioavailability, with subsequent almost immediate onset of pharmacological effect. Due to these superiorities, we developed sildenafil sublingual spray and tablet. Sildenafil in oleic acid, propylene glycol and microemulsion prepared by water phase (H2O), oil phase (oleic acid), surfactant (Tween 80) and cosurfa

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Noel, Sekoni D. "Rapid estrogen action in LHRH neurons : possible role of GPR30 /." 2008. http://www.library.wisc.edu/databases/connect/dissertations.html.

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Hyslop, David. "Delayed-onset Polymer Cross-linking using Functional Nitroxyls." Thesis, 2012. http://hdl.handle.net/1974/7275.

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New polymer cure chemistry is described, wherein the onset of free radical cross-linking is delayed without compromising cure yields. The addition of an acrylate-functionalized nitroxyl, 4-acryloyloxy-2,2,6,6-tetramethylpiperidine-N-oxyl (AOTEMPO), to a peroxide-cure formulation quenches free radical activity during the initial stages of the cross-linking process, trapping alkyl radicals as alkoxyamines that bear acrylate functionality. Polymer cross-linking by macro-radical combination is suppressed until all nitroxyl is consumed, at which point radical oligomerization of polymer-bound acryla

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Samenow, Jason Paul. "Weather regimes associated with the rapid onset of the fall season in the extratropical Northern Hemisphere." 2000. http://catalog.hathitrust.org/api/volumes/oclc/47657668.html.

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Thesis (M.S.)--University of Wisconsin--Madison, 2000.<br>Typescript. eContent provider-neutral record in process. Description based on print version record. Includes bibliographical references (leaves 89-92).

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Coutinho, Patrícia Pezo 1980. "Striatin, a novel protein involved in the nongenomic/rapid action of steroids." Doctoral thesis, 2013. http://hdl.handle.net/10451/7990.

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Tese de doutoramento, Bioquímica (Bioquímica Clínica), Universidade de Lisboa, Faculdade de Ciências, 2013<br>The cellular responses to steroids are mediated by two general mechanisms: genomic and rapid/nongenomic effects. Identification of the mechanisms underlying aldosterone’s rapid versus their genomic actions have been difficult to study and are not clearly understood. I explored the hypothesis that striatin is a critical intermediary of the rapid/nongenomic effects of aldosterone and that striatin serves as a novel link between the actions of the mineralocorticoid and estrogen receptors.

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Lin, Hsiu-Lien, and 林秀蓮. "Studies on Rapid Growth of Ovarian Follicles, and Blood Constituent Profiles Before and After Onset of Laying in Female White Roman Geese." Thesis, 2005. http://ndltd.ncl.edu.tw/handle/44351257971894542980.

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碩士<br>國立中興大學<br>畜產學系<br>93<br>The purpose of the present study was to investigate rapid growth of ovarian follicles, and the profiles of plasma estradiol, progesterone and blood constituents concentrations before and after onset of laying in female White Roman geese. The study was divided into two trials. In trial one, seven female White Roman geese during the first cycle of laying were used. Geese were housed in individual cages and exposed to 9 hrs of lighting (9L:15D) per day. The sudan red and sudan black dye capsules were administered on alternate days to avoid confusing in dating the col

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Chang, Ya-Han, and 張雅涵. "1. Develop an Analytical Platform for Rapid Detection of Polyphenol Compound Using Fullerene Based Mass Spectrometry2. Label-free Quantitative Metabolomics of Adults-Onset Still''s Disease." Thesis, 2015. http://ndltd.ncl.edu.tw/handle/12236868906537394787.

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碩士<br>國立中興大學<br>分子生物學研究所<br>103<br>[論文題目一] Matrix-assisted laser desorption / ionization time-of flight mass spectrometry, (MALDI-TOF MS) is a rapid and sensitive instrument for many biomolecules. However, there are interferences in the low-mass region (m/z of < 500) when using organic matrix, thereby it’s unsuitable for the analysis of small molecules. Fullerenes carbon particles has a strong absorption in the ultraviolet region and non-interference matrix signal in the lower molecular weight region and because their superconducting and unique optical qualities which is widely applied in biom

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Fundak, Robert. "Rapid establishment of emergency action areas as a consequence of large scale radioactive material releases from fixed nuclear facilities." Thesis, 1995. http://hdl.handle.net/1957/35225.

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Rapid emergency response decisions from a radiation release are necessary in order to prevent the general public from being exposed to a potential radiation hazard. A one meter exposure rate measurement is all that is necessary to establish relocation and food control areas when the ground is contaminated at the Protective Action Guide minimum response levels. With the results of these calculations, a known one meter exposure rate is all that is necessary to establish relocation and food control areas for a release from the WNP-2 commercial nuclear power plant or a release from a waste tank at

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莊瑩琦. "An action research on teaching public art appreciation to upper graders:taking Kaohsiung Mass Rapid Transit public art as subject matters." Thesis, 2009. http://ndltd.ncl.edu.tw/handle/06608508748494715415.

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Purvis, Troy Powell. "Nanoparticle formulations of poorly water soluble drugs and their action in vivo and in vitro." 2007. http://hdl.handle.net/2152/9766.

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Poorly water soluble drugs have been manipulated to make them more soluble, increasing the bioavailability of these drugs. Several cryogenic processes allow for production of drug nanoparticles, without mechanical stress that could cause degradation. The Ultra Rapid Freezing (URF) process is a technique which improves water solubility of drugs by reducing primary drug particle size by producing amorphous solid dispersions. Heat conduction is improved, using a cryogenic material with a high thermal conductivity relative to the solution being frozen to maintain the surface temperature and heat t

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Koblic, Zedková Iveta. "Psychopatologie schizofrenie s časným začátkem a její terapie se zaměřením na atypická neuroleptika." Doctoral thesis, 2016. http://www.nusl.cz/ntk/nusl-286922.

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OBJECTIVES: The aim of our study was to assess clinical presentation of early-onset schizophrenia spectrum disoders (EO-SSD), the time to first improvement and efficacy associated with selected atypical (AAPs) and typical (TAPs) antipsychotics, as well as two main side effects - weight gain and treatment-emergent extrapyramidal symptoms (EPSs) during the treatment in patients with EO-SSD. METHODS: This was a systematic chart review of all patients receiving routine clinical care in our department, with selected AAPs (risperidone, olanzapine, ziprasidone, quetiapine and clozapine) and TAPs (hal

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Engelken, Rainer. "Chaotic Neural Circuit Dynamics." Doctoral thesis, 2017. http://hdl.handle.net/11858/00-1735-0000-002E-E349-9.

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