Academic literature on the topic 'Redox labels'

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Journal articles on the topic "Redox labels"

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Koyappayil, Aneesh, and Min-Ho Lee. "Ultrasensitive Materials for Electrochemical Biosensor Labels." Sensors 21, no. 1 (2020): 89. http://dx.doi.org/10.3390/s21010089.

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Since the fabrication of the first electrochemical biosensor by Leland C. Clark in 1956, various labeled and label-free sensors have been reported for the detection of biomolecules. Labels such as nanoparticles, enzymes, Quantum dots, redox-active molecules, low dimensional carbon materials, etc. have been employed for the detection of biomolecules. Because of the absence of cross-reaction and highly selective detection, labeled biosensors are advantageous and preferred over label-free biosensors. The biosensors with labels depend mainly on optical, magnetic, electrical, and mechanical princip
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Le Gal La Salle, A., B. Limoges, S. Rapicault, C. Degrand, and P. Brossier. "New immunoassay techniques using Nafion-modified electrodes and cationic redox labels or enzyme labels." Analytica Chimica Acta 311, no. 3 (1995): 301–8. http://dx.doi.org/10.1016/0003-2670(95)00064-7.

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Evtugyn, Gennady A., Anna V. Porfireva, and Ivan I. Stoikov. "Electrochemical DNA sensors based on spatially distributed redox mediators: challenges and promises." Pure and Applied Chemistry 89, no. 10 (2017): 1471–90. http://dx.doi.org/10.1515/pac-2016-1124.

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AbstractDNA and aptasensors are widely used for fast and reliable detection of disease biomarkers, pharmaceuticals, toxins, metabolites and other species necessary for biomedical diagnostics. In the overview, the concept of spatially distributed redox mediators is considered with particular emphasis to the signal generation and biospecific layer assembling. The application of non-conductive polymers bearing redox labels, supramolecular carriers with attached DNA aptamers and redox active dyes and E-sensor concept are considered as examples of the approach announced.
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Iglesias-Mayor, Alba, Olaya Amor-Gutiérrez, Agustín Costa-García, and Alfredo de la Escosura-Muñiz. "Nanoparticles as Emerging Labels in Electrochemical Immunosensors." Sensors 19, no. 23 (2019): 5137. http://dx.doi.org/10.3390/s19235137.

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This review shows recent trends in the use of nanoparticles as labels for electrochemical immunosensing applications. Some general considerations on the principles of both the direct detection based on redox properties and indirect detection through electrocatalytic properties, before focusing on the applications for mainly proteins detection, are given. Emerging use as blocking tags in nanochannels-based immunosensing systems is also covered in this review. Finally, aspects related to the analytical performance of the developed devices together with prospects for future improvements and appli
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Ben Jrad, Amani, Hussein Kanso, Delphine Raviglione, Thierry Noguer, Nicolas Inguimbert, and Carole Calas-Blanchard. "Salen/salan metallic complexes as redox labels for electrochemical aptasensors." Chemical Communications 55, no. 85 (2019): 12821–24. http://dx.doi.org/10.1039/c9cc07575e.

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Hunt, Alexander, and Gymama Slaughter. "Electrochemical Strategies for MicroRNA Quantification Leveraging Amplification and Nanomaterials: A Review." Chemosensors 13, no. 7 (2025): 242. https://doi.org/10.3390/chemosensors13070242.

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MicroRNAs (miRNAs) are small, non-coding RNAs that regulate gene expression and have emerged as critical biomarkers in various diseases, including cancer. Their stability in bodily fluids and role as oncogenes or tumor suppressors make them attractive targets for non-invasive diagnostics. However, conventional detection methods, such as Northern blotting, RT-PCR, and microarrays, are limited by low sensitivity, lengthy protocols, and limited specificity. Electrochemical biosensors offer a promising alternative, providing high sensitivity, rapid response times, portability, and cost-effectivene
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Smiljanic, Milutin, Pierre Bleteau, Alexia Papageorgiou, Nathan Goffart, Catherine Adam, and Thomas Doneux. "Introducing common oxazine fluorophores as new redox labels for electrochemical DNA sensors." Bioelectrochemistry 155 (February 2024): 108582. http://dx.doi.org/10.1016/j.bioelechem.2023.108582.

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Ma, Xiaohua, Dehua Deng, Ning Xia, Yuanqiang Hao, and Lin Liu. "Electrochemical Immunosensors with PQQ-Decorated Carbon Nanotubes as Signal Labels for Electrocatalytic Oxidation of Tris(2-carboxyethyl)phosphine." Nanomaterials 11, no. 7 (2021): 1757. http://dx.doi.org/10.3390/nano11071757.

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Nanocatalysts are a promising alternative to natural enzymes as the signal labels of electrochemical biosensors. However, the surface modification of nanocatalysts and sensor electrodes with recognition elements and blockers may form a barrier to direct electron transfer, thus limiting the application of nanocatalysts in electrochemical immunoassays. Electron mediators can accelerate the electron transfer between nanocatalysts and electrodes. Nevertheless, it is hard to simultaneously achieve fast electron exchange between nanocatalysts and redox mediators as well as substrates. This work pres
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Grabowska, Iwona, Maria Hepel, and Katarzyna Kurzątkowska-Adaszyńska. "Advances in Design Strategies of Multiplex Electrochemical Aptasensors." Sensors 22, no. 1 (2021): 161. http://dx.doi.org/10.3390/s22010161.

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In recent years, the need for simple, fast, and economical detection of food and environmental contaminants, and the necessity to monitor biomarkers of different diseases have considerably accelerated the development of biosensor technology. However, designing biosensors capable of simultaneous determination of two or more analytes in a single measurement, for example on a single working electrode in single solution, is still a great challenge. On the other hand, such analysis offers many advantages compared to single analyte tests, such as cost per test, labor, throughput, and convenience. Be
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Kim, Gyeongho, and Haesik Yang. "(Invited) Electrochemical Biosensor Using Direct Electron Transfer and an Antibody–Aptamer Hybrid Sandwich." ECS Meeting Abstracts MA2024-02, no. 54 (2024): 3704. https://doi.org/10.1149/ma2024-02543704mtgabs.

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Direct electron transfer (DET) between an electrode and redox labels is feasible in electrochemical biosensors using small aptamer–aptamer sandwiches; however, its application is limited in biosensors that rely on larger antibody–antibody sandwiches. The development of sandwich-type biosensors utilizing DET is challenged by the scarcity of aptamer–aptamer sandwich pairs with high affinity in complex biological samples. In this presentation, we introduce an electrochemical biosensor using an antibody–aptamer hybrid sandwich for detecting thrombin in human serum. The biosensor enables rapid DET
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Dissertations / Theses on the topic "Redox labels"

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Gaillard, Michel. "Nouveaux marqueurs électroactifs pour le développement de biocapteurs environnementaux." Electronic Thesis or Diss., Perpignan, 2023. https://theses-public.univ-perp.fr/2023PERP0054.pdf.

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De nos jours, l'évolution du climat, les rejets anthropiques et l’augmentation de la population mondiale concourent à un accroissement du nombre de bactéries préoccupantes, des rejets médicamenteux et des toxines dans l’environnement. L’ochratoxine A, l’estradiol, et certaines bactéries font partie des contaminants polluant la nature et menaçant la santé des êtres vivants. Dans une optique de détection de ces éléments potentiellement dangereux, nous avons travaillé sur le développement d’un marquage original d'oligonucléotides. Ce marquage est basé sur l’utilisation de complexes métalliques él
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Ho, M. Y. "An investigation of redox self-assembled monolayer in label-free biosensor application." Thesis, University of Cambridge, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.604101.

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This dissertation investigates a label-free sensing platform which can be used to detect DNA, enzyme or protein, based upon electrochemical detection which is suitable for implementation in microarray form. Two implementations are proposed based on mixed Ferrocene self-assembled monolayer (SAM) and the Azurin (metalloprotein) SAM. We have shown for the first time that electro-active SAM, functionalized with suitable receptors, can be employed for the detection of biomolecular interactions. Detection of streptavidin by biotin-functionalized Ferrocene SAM was successfully demonstrated. These res
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Chandra, Sudeshna, Christian Gäbler, Christian Schliebe, Heinrich Lang, and Dhirendra Bahadur. "Fabrication of a label-free electrochemical immunosensor using a redox active ferrocenyl dendrimer." Universitätsbibliothek Chemnitz, 2017. http://nbn-resolving.de/urn:nbn:de:bsz:ch1-qucosa-220086.

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We report an IgG (=immunoglobulin) electrochemical immunosensor using a newly synthesized redox-active ferrocenyl dendrimer of generation 2 (G2Fc) as a voltammetric transducer. The ferrocenyl dendrimer N(CH2CH2C(O)NHCH2CH2NHC(O)Fe(η5-C5H4)(η5-C5H5))(CH2CH2N(CH2CH2C(O)NHCH2CH2NHC(O)Fe(η5-C5H4)(η5-C5H5))2)2 (G2Fc) was used as a functional moiety to immobilize the antibody on the surface of the electrode. A sandwich immunosensor of the type IgG/Bovine serum albumin (BSA)/anti-IgG/G2Fc/glassy carbon electrode (GCE) was fabricated. The electrochemical properties of G2Fc were thoroughly studied in a
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Zaccarin, Mattia. "Setting up of an innovative procedure for redox proteomics: and its application for definition of the redox status of cells with high metastatic potential." Doctoral thesis, Università degli studi di Padova, 2013. http://hdl.handle.net/11577/3423382.

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BACKGROUND: The cysteine (Cys) proteome includes 214.000 Cys with thiol and other forms. Of these, only a relatively small subset functions in cell signalling. Redox-active Cys are more susceptible to oxidation, and their oxidized form is more susceptible to reduction. Specific proteomic techniques are required to identify these modifications and to study their regulation in different cell processes that are collectively known as redox proteomics. Thus, it is of interest to be able to identify both the proteins and the cysteine residues affected, and to quantify the extent of the modification
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Kim, Sangkyung. "Redox cycling for an in-situ enzyme labeled immunoassay on interdigitated array electrodes." Diss., Available online, Georgia Institute of Technology, 2004:, 2004. http://etd.gatech.edu/theses/available/etd-08192004-105039/unrestricted/kim%5Fsangkyung%5F200412%5Fphd.pdf.

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Thesis (Ph. D.)--Biomedical Engineering, Georgia Institute of Technology, 2005.<br>Hesketh, Peter, Committee Chair ; Edmondson, Dale, Committee Member ; Frazier, Albert, Committee Member ; Hunt, William, Committee Member ; Janata, Jiri, Committee Member. Includes bibliographical references.
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Hou, Jue. "Characterizing Breast Cancer Invasive Potential Using Combined Label-Free Multiphoton Metabolic Imaging of Cellular Lipids and Redox State." Thesis, University of California, Irvine, 2017. http://pqdtopen.proquest.com/#viewpdf?dispub=10288401.

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<p> Aerobic glycolysis (Warburg effect) is accompanied by significant alterations in cellular redox state and constitutes one of the hallmarks of cancer cell metabolism. Label-free multi-photon microscopy (MPM) methods based on two-photon excited fluorescence (TPEF) have been used extensively to form high-resolution images of redox state in cells and tissues based on intrinsic NADH and FAD+ fluorescence. However, changes in cellular redox alone are insufficient to fully characterize cancer metabolism and predict invasive potential. We demonstrate that label-free MPM measurements of TPEF-derive
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Book chapters on the topic "Redox labels"

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Golubev, V. A., Yu N. Kozlov, A. N. Petrov, and A. P. Purmal. "Catalysis of Redox Processes by Nitroxyl Radicals." In Bioactive Spin Labels. Springer Berlin Heidelberg, 1992. http://dx.doi.org/10.1007/978-3-642-48724-8_4.

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Likhtenshtein, Gertz I. "Physical Label Techniques." In Chemical Physics of Redox Metalloenzyme Catalysis. Springer Berlin Heidelberg, 1988. http://dx.doi.org/10.1007/978-3-642-73100-6_3.

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Allen, John F., Paul N. Davies, Jens Forsberg, Gunilla Håkansson, and Anna Tullberg. "Acid-Labile, Histidine Phosphoproteins in Chloroplasts and Mitochondria: Possible Candidates for Redox Sensor Kinases." In Photosynthesis: from Light to Biosphere. Springer Netherlands, 1995. http://dx.doi.org/10.1007/978-94-009-0173-5_622.

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Gironi, Fabio. "Assessing the French Atheistic Turn." In Speculations 3. punctum books, 2012. https://doi.org/10.21983/p3.0010.1.16.

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In under a decade we have witnessed a proliferation of texts on “atheism,” so much so that the term “New Atheism”1 has become a widely employed label to describe the discourse of this intellectual current, and books propounding or opposing it compete on the shelves of bookstores. Mostly, unfortunately, the tone of this discourse ranges from the patronisingly sarcastic to the irresponsibly uninformed (in the case of atheism-friendly authors) and from the wisely condescending to the virulently obscurantist (in the case of religious apologists). Most commonly associ-ated with this movement are th
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Zanello, Piero. "STEREOCHEMICAL ASPECTS OF THE REDOX PROPENSITY OF HOMOMETAL CARBONYL CLUSTERS." In Chains, Clusters, Inclusion Compounds, Paramagnetic Labels, and Organic Rings. Elsevier, 1994. http://dx.doi.org/10.1016/b978-0-444-81581-1.50006-1.

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Olejniczak, Agnieszka B., and Zbigniew J. Leśnikowski. "Boron Clusters as Redox Labels for Nucleosides and Nucleic Acids." In Handbook of Boron Science. WORLD SCIENTIFIC (EUROPE), 2018. http://dx.doi.org/10.1142/9781786344670_0001.

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Robertson, Jeremy. "Redox deprotection." In Protecting Group Chemistry. Oxford University Press, 2000. http://dx.doi.org/10.1093/hesc/9780198502753.003.0005.

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This chapter focuses on redox deprotection. Oxidation-labile protecting groups offer a means of releasing functional groups under essentially neutral conditions which is useful when hydrolytic deprotection is not tolerated and silyl protecting groups are unsuitable. In particular, a CH<sub>2</sub> group that links a functional group to an electron-rich aromatic ring is prone to oxidation giving a hemiacetal, which is unstable with respect to aldehyde formation, and release of the functional group. Some oxidising agents activate the CH<sub>2</sub> towards nucleophilic attack by water in a proce
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Tamaki, Yusuke, and Osamu Ishitani. "CO2 Reduction Using Metal Complexes as Photocatalysts." In Redox-based Catalytic Chemistry of Transition Metal Complexes. Royal Society of Chemistry, 2024. https://doi.org/10.1039/9781837676484-00344.

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In this chapter, photocatalytic systems for the reduction of carbon dioxide (CO2) using metal complexes are discussed. To construct efficient photocatalytic CO2 reduction systems, two functions, i.e., redox photosensitizer and catalyst, are required. Metal complexes displaying visible-light absorption and long lifetimes in the excited states might be suitable for redox photosensitizers and redox-active metal complexes having a labile ligand forming a vacant site to activate CO2 can possibly be used as catalysts. Simple mixed systems of them photocatalyze the reduction of CO2. In addition, supr
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Junkefer, Clifford, David Rhouck, B. Mark Britt, Tobin R. Sosnick, and John L. Hanners. "[17] Biogenesis of pyrroloquinoline quinone from 3C-labeled tyrosine." In Redox-active amino acids in biology. Elsevier, 1995. http://dx.doi.org/10.1016/0076-6879(95)58049-2.

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Duca, Gheorghe, and Mikhail Yu Gorbachev. "Theories of electron and proton transfer and the need for their development." In Redox Processes with Electron and Proton Transfer. Moldova State University, 2023. http://dx.doi.org/10.59295/prtep2023_03.

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This chapter provides a detailed overview of the evolution of electron and proton transfer research. Significant contributions include Libby's 1952 model, for which R.A. Marcus, provided a solution to the problem of energy conservation in this model by proposing that energy levels can adjust through environmental fluctuations. Henry Taube, made essential contributions highlighting the differences between rigid and labile transition metal complexes in redox reactions. The mechanism of the synchronous transfer of an electron and a proton is also addressed, a consequence of the Frank-Condon princ
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Conference papers on the topic "Redox labels"

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Liu, Kunzan, Ellen L. Kan, Honghao Cao, et al. "Deep and Isotropic Structural and Metabolic Imaging for Nucleolar Dynamics in Living Biosystems." In Bio-Optics: Design and Application. Optica Publishing Group, 2025. https://doi.org/10.1364/boda.2025.dtu3a.3.

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We develop a multimode fiber-based, label-free 3D imaging system coupled with a large-scale axial deblurring network for deep and isotropic imaging, uncovering dynamic correlations between redox states and nucleolar activities in diverse living biosystems.
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Rodriguez, Marcos R., Malavika Nidhi, Divya M. Gollapalli, and Kyle P. Quinn. "Quantifying the Interaction between Age and Diabetes on Skin Wound Metabolism Using In Vivo Multiphoton Microscopy." In Clinical and Translational Biophotonics. Optica Publishing Group, 2024. http://dx.doi.org/10.1364/translational.2024.ts3b.4.

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Through longitudinal, in vivo label-free multiphoton microscopy, an optical redox ratio of FAD/(NADH+FAD) autofluorescence demonstrated how diabetes and advanced age affect skin metabolism during the stages of wound healing.
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Gillette, Amani, Shirsa Udgata, Lexie Schmitz, Dustin Deming, and Melissa C. Skala. "Wide-field optical redox imaging with leading-edge detection for assessment of patient-derived cancer organoids (Conference Presentation)." In Label-free Biomedical Imaging and Sensing (LBIS) 2023, edited by Natan T. Shaked and Oliver Hayden. SPIE, 2023. http://dx.doi.org/10.1117/12.2650100.

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Chen, Cheng-Chuan, Wan-Shao Tsai, and Pei-Kuen Wei. "Aqueous mercuric ions detection using electrochemical surface plasmon resonance in capped gold nanowire arrays." In JSAP-OSA Joint Symposia. Optica Publishing Group, 2017. http://dx.doi.org/10.1364/jsap.2017.5p_a410_10.

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Mercuric ion, inorganic metal ion, found in three oxidation state in nature, including elemental mercury (Hg0), mercurous ion (Hg+), and mercuric ion (Hg2+). These three forms possess hazardous environmental contaminant and are extremely toxic metal materials to damage mammalian organs.[1] This work demonstrates a label-free technique for Hg2+ ions detection using capped gold nanowire arrays based sensors[2] combined with the electrochemical surface plasmon resonance method. The three-electrode electrochemical analysis (Fig. 1) and optical transmission measurement were employed to characterize
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Halid, Nurul Izni Abdullah, Siti Aishah Hasbullah, Haslina Ahmad, Lee Yook Heng, Nurul Huda Abd Karim, and Siti Norain Harun. "Electrochemical DNA biosensor for detection of porcine oligonucleotides using ruthenium(II) complex as intercalator label redox." In THE 2014 UKM FST POSTGRADUATE COLLOQUIUM: Proceedings of the Universiti Kebangsaan Malaysia, Faculty of Science and Technology 2014 Postgraduate Colloquium. AIP Publishing LLC, 2014. http://dx.doi.org/10.1063/1.4895214.

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Doi, Hideo, Tomoko Horio, Young-Joon Choi, Kazuhiro Takahashi, Toshihiko Noda, and Kazuaki Sawada. "Redox-Type Label-Free ATP Image Sensor for Highly Sensitive in Vitro Imaging of Extracellular ATP." In 2021 21st International Conference on Solid-State Sensors, Actuators and Microsystems (Transducers). IEEE, 2021. http://dx.doi.org/10.1109/transducers50396.2021.9495500.

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Cheng, Chi Qin, Kok Sheik Wong, and Lay Ki Soon. "l2Match: Optimization Techniques on Subgraph Matching Algorithm Using Label Pair, Neighboring Label Index, and Jump-Redo Method." In 2024 International Conference on Electronics, Information, and Communication (ICEIC). IEEE, 2024. http://dx.doi.org/10.1109/iceic61013.2024.10457108.

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Bacciu, Davide, and Marco Podda. "Graphgen-redux: a Fast and Lightweight Recurrent Model for labeled Graph Generation." In 2021 International Joint Conference on Neural Networks (IJCNN). IEEE, 2021. http://dx.doi.org/10.1109/ijcnn52387.2021.9533743.

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Doi, Hideo, Tomoko Horio, Eiji Shigetomi, et al. "Label-Free Real-Time Imaging of Extracellular Lactate From a Hippocampal Slice Based on Charge-Transfer-Type Potentiometric Redox Sensor Arrays." In 2019 20th International Conference on Solid-State Sensors, Actuators and Microsystems & Eurosensors XXXIII (TRANSDUCERS & EUROSENSORS XXXIII). IEEE, 2019. http://dx.doi.org/10.1109/transducers.2019.8808447.

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