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Journal articles on the topic 'Regulatory role'

Author: Grafiati

Published: 30 May 2022

Last updated: 31 July 2025

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1

D Singh, Vishal. "The Ever-Expanding Role of Regulatory Affairs." International Journal of Science and Research (IJSR) 13, no. 2 (2024): 847–52. http://dx.doi.org/10.21275/sr24209205014.

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2

Alvarez, Clara Luz. "Regulatory State and Judicial Decisions in Telecommunications in Mexico." Law, State and Telecommunications Review 10, no. 1 (2018): 15–36. http://dx.doi.org/10.26512/lstr.v10i1.21498.

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Purpose – To assess the role of the judiciary in defining the Regulatory State and in regulating telecommunications in Mexico after almost 5 years of the creation of an independent regulator for telecommunications and broadcasting (Instituto Federal de Telecomunicaciones) with authority in antitrust matters. Methodology/approach/design – To identify the most relevant judicial decisions in telecommunications and antitrust matters, research upon the context in which they were adopted, analyze the content of the decisions and identify the impact of such judicial decisions in the constructio

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3

Zakaria, Ir Muhamad Sobri, Haslina Hassan, and Mohd Hizam Hanafiah. "REGULATORY MONITORING AND REGULATEE’S FIRM PERFORMANCE: AUDIT THEMATIC FINDING ON WATER OPERATOR PERFORMANCE IN MALAYSIAN WATER SERVICES INDUSTRY." Journal of Information System and Technology Management 4, no. 14 (2019): 34–46. http://dx.doi.org/10.35631/jistm.414004.

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This study provides a report of the audit thematic findings on the regulatory role of regulates firm performance. Based on the literature, audit activities are part of a monitoring mechanism that can improve firm performance in a situation where a controlling power such as holding shares and executive power does exist. However, in the context of the regulator and regulate relationship in the Malaysian water services industry, the regulator has the authority to control and monitor the regulator's firm performance. The regulator has monitoring power stipulated by law, the Water Services Industry

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Ambekar, Monika. "Role of Regulatory Affairs in Marketing Pharmaceutical Products." International Journal of Science and Research (IJSR) 11, no. 8 (2022): 1347–51. http://dx.doi.org/10.21275/sr22820145454.

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Hallur, Giri Gundu, and Vivek S. Sane. "Indian telecom regulatory framework in comparison with five countries: structure, role description and funding." Digital Policy, Regulation and Governance 20, no. 1 (2018): 62–77. http://dx.doi.org/10.1108/dprg-06-2017-0035.

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Purpose The purpose of this paper is to present a cross-country qualitative comparative analysis of telecom regulatory frameworks of five countries with that of India. Adopting an institutionalist approach, this paper contributes to understanding of how institutional frameworks in these five countries are structured as compared to that in India so as to ensure division of the authority and scope of the regulator vis-a-vis that of the ministry, and the bureaucracy; financial autonomy of the regulator; redressal of grievances of individual consumers; and modification in the framework to cater to

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Prihatiningsih, Titi Savitri. "The Role of Indonesian Medical Council in Assuring The Quality of Medical Education." Jurnal Pendidikan Kedokteran Indonesia: The Indonesian Journal of Medical Education 5, no. 3 (2016): 181. http://dx.doi.org/10.22146/jpki.25452.

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Background: Indonesian Medical Council (IMC) was established in October 2005 as mandated by the Medical Practice Law No.29/2004. The main function of IMC is to safeguard the medical practices through several mechanism, one of which is through ensuring the quality of medical education by approving the standards of competences and standards of medical education as well as by monitoring the implementation of those standards. A new Medical Education Law No.20/2013 is enacted. In this Law, the role of IMC in assuring the quality of medical education disappeared.Method: This is an exploratory qualit

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Pires Leal, Andrei. "COLLABORATIVE REGULATION." Law, State and Telecommunications Review 13, no. 1 (2021): 40–69. http://dx.doi.org/10.26512/lstr.v13i1.38201.

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Purpose - The purpose of this paper is to analyze in theory and practice the extent and ways the role of regulators in collaborative regulatory systems differs from their roles in more traditional, state-led regulatory systems. Methodology/Approach/Design - The descriptive and analytical methodology of this paper is supported by primary and secondary sources of research data: books, newspapers, official documentation, independent reports, and private stakeholders’ analysis. Moreover, field experiences of eminent professionals and senior civil servants have also been taken into considerat

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Otálora-Otálora, Beatriz Andrea, Cristian González Prieto, Lucia Guerrero, et al. "Identification of the Transcriptional Regulatory Role of RUNX2 by Network Analysis in Lung Cancer Cells." Biomedicines 10, no. 12 (2022): 3122. http://dx.doi.org/10.3390/biomedicines10123122.

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The use of a new bioinformatics pipeline allowed the identification of deregulated transcription factors (TFs) coexpressed in lung cancer that could become biomarkers of tumor establishment and progression. A gene regulatory network (GRN) of lung cancer was created with the normalized gene expression levels of differentially expressed genes (DEGs) from the microarray dataset GSE19804. Moreover, coregulatory and transcriptional regulatory network (TRN) analyses were performed for the main regulators identified in the GRN analysis. The gene targets and binding motifs of all potentially implicate

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9

Fedorov, S. I., and N. R. Galimova. "Role of Regulatory Contract in Control of Economic Concentration Transactions." Scientific Research of Faculty of Economics. Electronic Journal 12, no. 3 (2020): 31–53. http://dx.doi.org/10.38050/2078-3809-2020-12-3-31-53.

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This paper examines the application of the regulatory contract in the practice of economic concentration regulation from the standpoint of the theory of incomplete contracts. Based on the identification of transaction costs that arise at different stages of the conclusion and implementation of the contract, the limited rationality of both parties (including the regulator) is found. That leads us to the incompleteness of the contract. The involvement of the trustee institution in the regulatory contract is associated with the regulator's desire to remove some of the problems caused by the incom

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Krylov, Denys, and Anton Chub. "THE CONCEPT, ESSENCE AND ROLE OF REGULATORY POLICY INECONOMY DEVELOPMENT." Scientific bulletin of Polissia, no. 1(22) (2021): 6–15. http://dx.doi.org/10.25140/2410-9576-2021-1(22)-6-15.

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The article proves that the main controllers of the effectiveness of regulatory policy are independent analitical centres, business associations and other non-governmental organizations. As reasons for the low quality of legal support, it is noted the complete secrecy of public authorities from citizens during the submission, discussion and decision-making.The main task of the study is to analyze the experience gained and generalize the existing conceptual framework to determine the nature and role of regulatory policy in the development of a market economy.It was found that from the point of

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Epstein, Jay, Rainer Seitz, Neelam Dhingra, et al. "Role of regulatory agencies." Biologicals 37, no. 2 (2009): 94–102. http://dx.doi.org/10.1016/j.biologicals.2009.01.004.

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12

SLAVKOVA, Alla. "FISCAL AND REGULATORY ROLE OF INDIRECT TAXES IN UKRAINE." Herald of Khmelnytskyi National University. Economic sciences 322, no. 5 (2023): 374–78. http://dx.doi.org/10.31891/2307-5740-2023-322-5-59.

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The article analyzes the fiscal and regulatory role of indirect taxes in Ukraine. The advantages and disadvantages of indirect taxes in Ukraine are identified. The revenues from indirect taxes in the structure of the consolidated budget of Ukraine for 2017-2022 are analyzed. The directions for increasing the level of fiscal efficiency of indirect taxes are highlighted. The regulatory role of indirect taxes for the state budget of Ukraine is determined. Thus, the fiscal significance of indirect taxes has become less due to the economic, social and political changes that have taken place in the

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13

Thompson, Catriona M. A., James P. J. Hall, Govind Chandra, et al. "Plasmids manipulate bacterial behaviour through translational regulatory crosstalk." PLOS Biology 21, no. 2 (2023): e3001988. http://dx.doi.org/10.1371/journal.pbio.3001988.

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Beyond their role in horizontal gene transfer, conjugative plasmids commonly encode homologues of bacterial regulators. Known plasmid regulator homologues have highly targeted effects upon the transcription of specific bacterial traits. Here, we characterise a plasmid translational regulator, RsmQ, capable of taking global regulatory control in Pseudomonas fluorescens and causing a behavioural switch from motile to sessile lifestyle. RsmQ acts as a global regulator, controlling the host proteome through direct interaction with host mRNAs and interference with the host’s translational regulator

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Vantaggiato, Francesca P. "The drivers of regulatory networking: policy learning between homophily and convergence." Journal of Public Policy 39, no. 3 (2018): 443–64. http://dx.doi.org/10.1017/s0143814x18000156.

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AbstractThe literature on transnational regulatory networks identified interdependence as their main rationale, downplaying domestic factors. Typically, relevant contributions use the word “network” only metaphorically. Yet, informal ties between regulators constitute networked structures of collaboration, which can be measured and explained. Regulators choose their frequent, regular network partners. What explains those choices? This article develops an Exponential Random Graph Model of the network of European national energy regulators to identify the drivers of informal regulatory networkin

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Maggetti, Martino, Christian Ewert, and Philipp Trein. "Not Quite the Same." ANNALS of the American Academy of Political and Social Science 670, no. 1 (2017): 152–69. http://dx.doi.org/10.1177/0002716217691240.

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This article compares the role of regulatory intermediaries in the governance of pharmaceuticals and medical devices in Australia and Switzerland. We argue that the creation, selection, and activation of specific intermediaries depend on the organizational capacity of the regulator and on the potential of the intermediary to be captured by the target. To limit the risk of capture of intermediaries where the regulated industries are powerful, regulators tend to keep intermediaries under their control. To do so, the regulator must be well-funded and well-staffed, or supported by its political pr

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Koenig-Archibugi, Mathias, and Kate Macdonald. "The Role of Beneficiaries in Transnational Regulatory Processes." ANNALS of the American Academy of Political and Social Science 670, no. 1 (2017): 36–57. http://dx.doi.org/10.1177/0002716216688862.

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The editors of this volume highlight the role of intermediaries, alongside regulators and targets, as a way to better understand the outcomes of regulatory processes. Here, we explore the benefits of distinguishing a fourth category of actors: the groups whose interests the rules are meant to protect, the (intended) beneficiaries. We apply that framework to nonstate regulation of labor conditions, where the primary intended beneficiaries are workers and their families, especially in poorer countries. We first outline the different ways in which beneficiaries can relate to regulators, intermedi

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Servetas, Stephanie L., Beth M. Carpenter, Kathryn P. Haley, Jeremy J. Gilbreath, Jennifer A. Gaddy, and D. Scott Merrell. "Characterization of Key Helicobacter pylori Regulators Identifies a Role for ArsRS in Biofilm Formation." Journal of Bacteriology 198, no. 18 (2016): 2536–48. http://dx.doi.org/10.1128/jb.00324-16.

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ABSTRACTHelicobacter pylorimust be able to rapidly respond to fluctuating conditions within the stomach. Despite this need for constant adaptation,H. pyloriencodes few regulatory proteins. Of the identified regulators, the ferric uptake regulator (Fur), the nickel response regulator (NikR), and the two-component acid response system (ArsRS) are each paramount to the success of this pathogen. While numerous studies have individually examined these regulatory proteins, little is known about their combined effect. Therefore, we constructed a series of isogenic mutant strains that contained all po

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18

Abdulmalik, Salau, and Ayoib Che-Ahmad. "Regulatory changes and reporting quality: the moderating role of firm characteristics." Problems and Perspectives in Management 17, no. 2 (2019): 32–50. http://dx.doi.org/10.21511/ppm.17(2).2019.03.

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The objective of this study is to investigate the effect of regulatory changes on financial reporting quality and audit fees and to further test whether this effect was moderated by firm characteristics (i.e. abnormal audit fees, political connections and overlapping directorship) in Nigeria. This study utilized the data of 90 companies listed on the Nigerian stock exchange over the period 2008–2013. Using Generalized Method of Moments (GMM) technique that takes into account the endogeneity nature of financial reporting quality and audit fees model, the results indicated that financial reporti

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19

Warren, Patrick L., and Tom S. Wilkening. "Regulatory fog: The role of information in regulatory persistence." Journal of Economic Behavior & Organization 84, no. 3 (2012): 840–56. http://dx.doi.org/10.1016/j.jebo.2012.10.005.

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20

Ahmad, Alaassar, Mention Anne-Laure, and Helge Aas Tor. "Exploring how social interactions influence regulators and innovators: The case of regulatory sandboxes." Technological Forecasting and Social Change 160 (August 21, 2020): 120257. https://doi.org/10.1016/j.techfore.2020.120257.

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Like incubators, regulatory sandboxes constitute a prominent mechanism to enable entrepreneurial activities that guide financial technology (FinTech) firms through regulatory frameworks in the financial industry. Because they are new, there is a lack of research on regulatory sandboxes; most studies have investigated legal aspects while overlooking the management perspective. To address this gap, this paper builds on incubation research studies to explore how social interactions within regulatory sandboxes influence the practices of regulators and regulatees, using social capital theory. An ex

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21

Honig, P. K., and S.-M. Huang. "Regulatory Science and the Role of the Regulator in Biomedical Innovation." Clinical Pharmacology & Therapeutics 91, no. 3 (2012): 347–52. http://dx.doi.org/10.1038/clpt.2011.352.

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22

Harrison, Rowland J., Lars Olthafer, and Katie Slipp. "Federal and Alberta Energy Project Regulation Reform — At What Cost Efficiency?" Alberta Law Review 51, no. 2 (2013): 249. http://dx.doi.org/10.29173/alr67.

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Changes to regulatory regimes at the federal and provincial levels have recently transformed the way that energy resource projects will be considered and approved. The federal Canadian Environmental Assessment Act, 2012 and amended National Energy Board Act, along with the Alberta Responsible Energy Development Act, have taken decision-making power away from the regulators to government in an effort to align regulatory decisions with broader government policies. This article examines a number of the effects of the new regimes including the impact that the changes might have on the role of the

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23

Patankar, Arati V., and Juan E. Gonzï¿½lez. "An Orphan LuxR Homolog of Sinorhizobium meliloti Affects Stress Adaptation and Competition for Nodulation." Applied and Environmental Microbiology 75, no. 4 (2008): 946–55. http://dx.doi.org/10.1128/aem.01692-08.

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ABSTRACT The Sin/ExpR quorum-sensing system of Sinorhizobium meliloti plays an important role in the symbiotic association with its host plant, Medicago sativa. The LuxR-type response regulators of the Sin system include the synthase (SinI)-associated SinR and the orphan regulator ExpR. Interestingly, the S. meliloti Rm1021 genome codes for four additional putative orphan LuxR homologs whose regulatory roles remain to be identified. These response regulators contain the characteristic domains of the LuxR family of proteins, which include an N-terminal autoinducer/response regulatory domain and

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SALIU, Argëtim. "STATUS OF INDEPENDENT REGULATORY AGENCIES IN THE REPUBLIC OF NORTH MACEDONIA." International Journal of Legal Sciences-JUSTICIA 12, no. 21-22 (2024): 10–14. http://dx.doi.org/10.62792/ut.jus.v12.i21-22.p2748.

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The nineteenth and twentieth century determined a special connection and interdependence between political and economic branches , which set the right platform for presentation of the bodies or regulatory authorities. Macedonia was not overlooked by this connected determinism and interdependent. The formation of regulatory bodies by the Assembly in more diverse sectors in Macedonia began in 2002. The regulatory bodies have the status of legal entity by registration in court and their work is public. The role of the market, politics / government and civil society as a regulator with economic an

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Mohammadnia-Afrouzi, Mousa, Mehdi Shahbazi, Sedigheh Baleghi Damavandi, Ghasem Faghanzadeh Ganji, and Soheil Ebrahimpour. "Regulatory T-cell: Regulator of Host Defense in Infection." Journal of Molecular Biology Research 7, no. 1 (2017): 9. http://dx.doi.org/10.5539/jmbr.v7n1p9.

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Based on diverse activities and production of several cytokines, T lymphocytes and T helper cells are divided into Th1, Th2, Th17 and regulatory T-cell (T regs) subsets based on diverse activities and production of several cytokines. Infectious agents can escape from host by modulation of immune responses as effector T-cells and Tregs. Thus, regulatory T-cells play a critical role in suppression of immune responses to infectious agents such as viruses, bacteria, parasites and fungi and as well as preserving immune homeostasis. However, regulatory T-cell responses can advantageous for the body

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Evans-Marin, Heather L., Anthony T. Cao, Suxia Yao, et al. "Unexpected Regulatory Role of CCR9 in Regulatory T Cell Development." PLOS ONE 10, no. 7 (2015): e0134100. http://dx.doi.org/10.1371/journal.pone.0134100.

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27

Balaji, Snikdha, and Vedam Anand Kumar. "Cyber Warfare and Attribution: Exploring the Regulatory Role of International Law." International Journal of Science and Research (IJSR) 12, no. 12 (2023): 372–75. http://dx.doi.org/10.21275/sr231204073934.

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Johnson, Chris. "Role of Regulators in Safeguarding the Interface Between Autonomous Systems and the General Public." Journal of System Safety 53, no. 2 (2017): 27–34. http://dx.doi.org/10.56094/jss.v53i2.91.

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Regulators play a critical role in the commercial exploitation of new technologies. They protect the public when market competition might persuade companies to take undue risks. At the same time, it is essential that regulatory authorities do not kill innovation by imposing inappropriate rules or by retaining previous requirements that make little sense in the light of technical innovations. These tensions are apparent in the introduction of autonomous and semi-autonomous systems, across a range of industries. “Regulatory lag” has starved companies of the strategic guidance that is necessary t

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Jenabian, Mohammad-Ali, Petronela Ancuta, Norbert Gilmore, and Jean-Pierre Routy. "Regulatory T Cells in HIV Infection: Can Immunotherapy Regulate the Regulator?" Clinical and Developmental Immunology 2012 (2012): 1–12. http://dx.doi.org/10.1155/2012/908314.

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Regulatory T cells (Tregs) have a dominant role in self-tolerance and control of autoimmune diseases. These cells also play a pivotal role in chronic viral infections and cancer by limiting immune activation and specific immune response. The role of Tregs in HIV pathogenesis remains poorly understood as their function, changes according to the phases of infection. Tregs can suppress anti-HIV specific responses and conversely can have a beneficial role by reducing the deleterious impact of immune activation. We review the frequency, function and homing potential of Tregs in the blood and lympho

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Hyytiäinen, Heidi, Marcos Montesano, and E. Tapio Palva. "Global Regulators ExpA (GacA) and KdgR Modulate Extracellular Enzyme Gene Expression Through the RsmA-rsmB System in Erwinia carotovora subsp. carotovora." Molecular Plant-Microbe Interactions® 14, no. 8 (2001): 931–38. http://dx.doi.org/10.1094/mpmi.2001.14.8.931.

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The production of the main virulence determinants, the extracellular plant cell wall-degrading enzymes, and hence virulence of Erwinia carotovora subsp. carotovora is controlled by a complex regulatory network. One of the global regulators, the response regulator ExpA, a GacA homolog, is required for transcriptional activation of the extracellular enzyme genes of this soft-rot pathogen. To elucidate the mechanism of ExpA control as well as interactions with other regulatory systems, we isolated second-site transposon mutants that would suppress the enzyme-negative phenotype of an expA (gacA) m

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Sainsbury, Sarah, Jingshan Ren, Nigel J. Saunders, David I. Stuart, and Raymond J. Owens. "Structure of the regulatory domain of the LysR family regulator NMB2055 (MetR-like protein) fromNeisseria meningitidis." Acta Crystallographica Section F Structural Biology and Crystallization Communications 68, no. 7 (2012): 730–37. http://dx.doi.org/10.1107/s1744309112010603.

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The crystal structure of the regulatory domain of NMB2055, a putative MetR regulator fromNeisseria meningitidis, is reported at 2.5 Å resolution. The structure revealed that there is a disulfide bond inside the predicted effector-binding pocket of the regulatory domain. Mutation of the cysteines (Cys103 and Cys106) that form the disulfide bond to serines resulted in significant changes to the structure of the effector pocket. Taken together with the high degree of conservation of these cysteine residues within MetR-related transcription factors, it is suggested that the Cys103 and Cys106 resid

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He, Xiaoyuan, and Shuishu Wang. "Structural basis of DNA sequence recognition by the response regulator PhoP." Acta Crystallographica Section A Foundations and Advances 70, a1 (2014): C1409. http://dx.doi.org/10.1107/s2053273314085908.

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The PhoP-PhoR two-component system plays a key role in regulating virulence of Mycobacterium tuberculosis. The response regulator PhoP is a transcription regulator, and it regulates expression of more than 100 genes. PhoP belongs to the OmpR/PhoB subfamily of response regulators. Despite extensive research in recent years, the molecular mechanism of DNA sequence recognition by this large subfamily of response regulators is not fully understood, especially the role of the N-terminal regulatory domain on DNA binding of the effector domain. Here we present a crystal structure of the full-length P

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Al-Harbi, Ahmad. "Navigating Ethics and Regulation: The Role of AI in Modern Financial Services." Asian Journal of Economics, Business and Accounting 25, no. 1 (2025): 325–35. https://doi.org/10.9734/ajeba/2025/v25i11653.

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In this paper, I delve into the ethical and regulatory aspects of using artificial intelligence (AI) in the finance sector. As AI technologies increasingly influence financial decision-making, addressing issues of fairness, transparency, and regulation becomes crucial. The research will involve reviewing relevant academic literature, industry reports, and regulatory documents to gather information and insights on the ethical and regulatory dimensions of AI in finance. My research focuses on three main areas: the presence of bias in AI-driven financial decisions, the regulatory challenges hinde

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Popov, T., S. Giragosyan, V. Petkova, et al. "Regulatory Role of microRNAs in Tumor Angiogenesis." Acta Medica Bulgarica 47, no. 1 (2020): 67–72. http://dx.doi.org/10.2478/amb-2020-0012.

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AbstractThe process of neoangiogenesis is one of the classic hallmarks of a cancer. Its intricate mechanisms have long been one of the major domains in cancer research and a hope for a therapeutic breakthrough. Last decade a new subgroup of non-coding RNA molecules was reported called microRNAs. Literally hundreds of new molecules in this class are being uncovered as pivotal regulators in virtually all intracellular processes. The aim of this study is to classify and review those microRNA molecules that have a role in the processes of tumor angiogenesis and map their places in the regulatory f

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Rosario, Gracy X., Samuel Brown, Subhradip Karmakar, Mohammad A. Karim Rumi, and Nihar R. Nayak. "Super-Enhancers in Placental Development and Diseases." Journal of Developmental Biology 13, no. 2 (2025): 11. https://doi.org/10.3390/jdb13020011.

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The proliferation of trophoblast stem (TS) cells and their differentiation into multiple lineages are pivotal for placental development and functions. Various transcription factors (TFs), such as CDX2, EOMES, GATA3, TFAP2C, and TEAD4, along with their binding sites and cis-regulatory elements, have been studied for their roles in trophoblast cells. While previous studies have primarily focused on individual enhancer regions in trophoblast development and differentiation, recent attention has shifted towards investigating the role of super-enhancers (SEs) in different trophoblast cell lineages.

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Kuipers, Hedwich, and Peter van den Elsen. "Putative Immune Regulatory Role of Statins." Current Immunology Reviews 2, no. 1 (2006): 55–64. http://dx.doi.org/10.2174/157339506775471938.

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Song, Runxian, Faujiah Nurhasanah Ritonga, Haiyang Yu, Changjun Ding, and Xiyang Zhao. "Plant Melatonin: Regulatory and Protective Role." Horticulturae 8, no. 9 (2022): 810. http://dx.doi.org/10.3390/horticulturae8090810.

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Melatonin is an antioxidant that is widely distributed in plants and animals. It is a conservative molecule. In early studies, scientists often used isolation and identification techniques to observe whether the endogenous melatonin cycle in plants was related to the external photoperiod, plant growth, and development cycles, including seed germination, plant rooting, and floral induction. With the development of isolation and identification technology, there is ample evidence that plants possess a variety of melatonin-synthesis pathways. The comprehensive application of molecular biology, gen

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Daykin, C. D. "The Regulatory Role of the Actuary." British Actuarial Journal 5, no. 3 (1999): 529–74. http://dx.doi.org/10.1017/s1357321700000568.

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ABSTRACTThe actuary has played a role in regulation in the United Kingdom since 1819. More recently, in 1974, the Appointed Actuary system was introduced for life insurance companies, backed by strong professional guidance. Derivatives of the Appointed Actuary concept have been implemented in a number of other countries. Meanwhile, in the UK, defined benefit occupational pension schemes are now required to appoint a Scheme Actuary, who has a statutory whistle-blowing role under the Pensions Act 1995. A number of statutory roles for pension actuaries were in place prior to this. In general insu

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Altmann, Daniel M. "The immune regulatory role of neutrophils." Immunology 156, no. 3 (2019): 215–16. http://dx.doi.org/10.1111/imm.13049.

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Bell, Elaine. "New regulatory role for NK cells." Nature Reviews Immunology 7, no. 7 (2007): 496. http://dx.doi.org/10.1038/nri2118.

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41

Birringer, Marc, and Stefan Lorkowski. "Vitamin E: Regulatory role of metabolites." IUBMB Life 71, no. 4 (2018): 479–86. http://dx.doi.org/10.1002/iub.1988.

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C., R. Bansod* A. K. Hatkar R. M. Kawade. "Role of regulatory intelligence in pharmacovigilance." International Journal in Pharmaceutical Sciences 1, no. 12 (2023): 294–306. https://doi.org/10.5281/zenodo.10369284.

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In this project have given Information and regulatory documentation play inessential part in the decision-making within the company. It is particularly true in these actor of the pharmaceutical industry, in which a good risk management is essential. To find this information,to manage and to analyze, require the installation of an adapted regulatory intelligence, structured,exhaustive and relevant. Therefore, rigorous process (search of sources, data' collection, diffusion and analyze) is the necessary condition for the setting up of are regulatory environmental scanning system, as well asthead

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Lahat, Lihi. "Changing Expectations? The Change in the Role of the Welfare Ministry in the Regulation of Personal Social Services." ANNALS of the American Academy of Political and Social Science 691, no. 1 (2020): 153–73. http://dx.doi.org/10.1177/0002716220959310.

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Many welfare states have increased their regulatory role, but little attention has been given to historical changes in the regulatory role of government ministries. This study embraces a mezzo perspective and explores the regulatory role of the Welfare Ministry of Israel in the field of personal social services, asking the following questions: 1) What are the changes in regulatory expectations versus practices over the last five decades? and 2) How can we explain these changes and their outcomes? The study is based on the qualitative analysis of comptroller reports and other resources. It reve

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Xu, Yurong, Wanlian Xu, Jing Yi, et al. "Transcriptomics-Guided Investigation of the SLCG_Lrp Regulon Provides New Insights into Its Role for Lincomycin Biosynthesis." Fermentation 9, no. 4 (2023): 396. http://dx.doi.org/10.3390/fermentation9040396.

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Lincomycin industrially produced by Streptomyces lincolnensis can be adopted to treat infections caused by Gram-positive bacteria. SLCG_Lrp, a transcriptional regulator of the Lrp family, was first identified to positively regulate lincomycin biosynthesis. However, the regulatory role of SLCG_Lrp is yet to be elucidated. This study utilized RNA-seq for comparing the transcriptome profile of original-strain LCGL and the ΔSLCGL_Lrp mutant. A total of 244 genes comprising 116 downregulated and 128 upregulated genes were differentially expressed between LCGL and ΔSLCGL_Lrp. An in-depth analysis re

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Adefioye, Edumaretola Gabriel. "The Role of Regulatory Frameworks in Promoting Renewable Energy Investment in Nigeria." International Journal of Research Publication and Reviews 6, no. 4 (2025): 9369–79. https://doi.org/10.55248/gengpi.6.0425.1570.

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Kourula, Arno, Markus Paukku, Andrew Peterman, and Mikko Koria. "Intermediary roles in regulatory programs: Toward a role‐based framework." Regulation & Governance 13, no. 2 (2018): 141–56. http://dx.doi.org/10.1111/rego.12226.

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Shree, Bakhya, та Vivek Sharma. "Role of Non-Coding RNAs in TGF-β Signalling in Glioma". Brain Sciences 13, № 10 (2023): 1376. http://dx.doi.org/10.3390/brainsci13101376.

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Brain tumours and Gliomas, in particular, are among the primary causes of cancer mortality worldwide. Glioma diagnosis and therapy have not significantly improved despite decades of efforts. Autocrine TGF-β signalling promotes glioma proliferation, invasion, epithelial-to-mesenchymal transition (EMT), and drug resistance. Non-coding RNAs such as miRNA, lncRNA, and circRNAs have emerged as critical transcriptional and post-transcriptional regulators of TGF-β pathway components in glioma. Here, we summarize the complex regulatory network among regulatory ncRNAs and TGF-β pathway during Glioma pa

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Dai, Gu, Yan Qian, Jie Chen, et al. "Calmodulin activation of polo-like kinase 1 is required during mitotic entry." Biochemistry and Cell Biology 91, no. 5 (2013): 287–94. http://dx.doi.org/10.1139/bcb-2013-0015.

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Polo-like kinase 1 (Plk1) is a conserved key regulator of the G2/M transition, but its upstream spatiotemporal regulators remain unknown. With the help of immunofluorescence, co-immunoprecipitation, and glutathione S-transferase (GST) pull-down assay, we found that calmodulin (CaM) is one such regulatory molecule that associates with Plk1 from G2 to metaphase. More importantly, this interaction results in considerable stimulation of Plk1 kinase activity leading to hyperphosphorylation of Cdc25C. Our results provide new insight into the role of CaM as an upstream regulator of Plk1 activation du

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Deng, Bellanti, and Zheng. "Essential Kinases and Transcriptional Regulators and Their Roles in Autoimmunity." Biomolecules 9, no. 4 (2019): 145. http://dx.doi.org/10.3390/biom9040145.

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Kinases and transcriptional regulators are fundamental components of cell signaling that are expressed on many types of immune cells which are involved in secretion of cytokines, cell proliferation, differentiation, and apoptosis. Both play important roles in biological responses in health as well as in illnesses such as the autoimmune diseases which comprise at least 80 disorders. These diseases are caused by complex genetic and environmental interactions that lead to a breakage of immunologic tolerance and a disruption of the balance between self-reactive cells and regulatory cells. Kinases

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Yi, Chen, and Ahmed Razman Bin Abdul Latiff. "The Role of Regulatory Frameworks in Shaping the Firm Value of Cross-Listed Companies: A Comparative Analysis." Journal of Digitainability, Realism & Mastery (DREAM) 3, no. 04 (2024): 10–25. http://dx.doi.org/10.56982/dream.v3i04.225.

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This study examines the impact of regulatory frameworks on the firm value of cross-listed companies in Hong Kong and Mainland China, employing Institutional and Agency theories as analytical lenses. The research primarily utilizes quantitative methodologies, analysing secondary data sourced from financial databases and regulatory bodies. Key findings indicate that stringent regulatory compliance in Hong Kong correlates with higher firm values compared to Mainland China. Effective enforcement of regulations in Hong Kong also reduces information asymmetry, thereby increasing firm value. Converse

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