Academic literature on the topic 'Renal toxicity'

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Journal articles on the topic "Renal toxicity"

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Lindsley, Carol B., and Bradley A. Warady. "Renal Toxicity." Clinical Pediatrics 29, no. 1 (1990): 10–13. http://dx.doi.org/10.1177/000992289002900101.

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Mrvos, Rita, Tara L. Pummer, and Edward P. Krenzelok. "Amoxicillin Renal Toxicity." Pediatric Emergency Care 29, no. 5 (2013): 641–43. http://dx.doi.org/10.1097/pec.0b013e31828e9e78.

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Gentz, Brenda A., and T. Philip Malan. "Renal Toxicity with Sevoflurane." Drugs 61, no. 15 (2001): 2155–62. http://dx.doi.org/10.2165/00003495-200161150-00001.

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Farrugia, Emanuel, and Timothy S. Larson. "Drug-induced renal toxicity." Postgraduate Medicine 90, no. 2 (1991): 241–48. http://dx.doi.org/10.1080/00325481.1991.11701021.

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Crowell, J. A. "Resveratrol-Associated Renal Toxicity." Toxicological Sciences 82, no. 2 (2004): 614–19. http://dx.doi.org/10.1093/toxsci/kfh263.

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Labaye, Jacques, Damien Sarret, Christan Duvic, et al. "Renal toxicity of Oxaliplatin." Nephrology Dialysis Transplantation 20, no. 6 (2005): 1275–76. http://dx.doi.org/10.1093/ndt/gfh826.

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K., Sara. "PPI INDUCED RENAL TOXICITY." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES o6, no. 02 (2019): 4321–26. https://doi.org/10.5281/zenodo.2574961.

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<em>PPIs are mostly used drugs in many prescriptions along with drugs for other co-morbidities and also used for long time periods and as OTC drugs (medication). These drugs on prolong use causes renal toxicity in many cases by affecting glomerular filtration and also through several cases like increase in pH, gastroenteritis, hyperplasia, hypertrophy, hypergastrinemia, hyperchlorhydria, and effect on mitochondrial cells. The unrequited actions by PPIs also can appear in paediatrics along with adults. In this paper we will review about brief information regarding pharmacokinetics and pharmacod
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Perazella, Mark A. "Renal Vulnerability to Drug Toxicity." Clinical Journal of the American Society of Nephrology 4, no. 7 (2009): 1275–83. http://dx.doi.org/10.2215/cjn.02050309.

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Alan Selçuk, Nalan, and Türkay Toklu. "Renal Toxicity After Radionuclide Therapy." Nuclear Medicine Seminars 5, no. 3 (2019): 207–12. http://dx.doi.org/10.4274/nts.galenos.2019.0029.

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Gonçalves, MD, Ferraz. "Morphine toxicity in renal failure." Journal of Opioid Management 2, no. 3 (2006): 174. http://dx.doi.org/10.5055/jom.2006.0027.

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Dissertations / Theses on the topic "Renal toxicity"

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Magnusson, Emma. "Ouabain Toxicity -Selectivity Towards Renal Cancer Cells." Thesis, KTH, Skolan för kemi, bioteknologi och hälsa (CBH), 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-278574.

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Ouabain and other cardiotonic steroids are known to inhibit Na + ,K + -ATPase (NKA), theion pump responsible for the ionic gradient across the plasma membrane. These steroidsdisplay a selective toxicity towards several tumour cells in comparison to primary humancells, however, the mechanism behind this is not yet understood. Here, we examined theouabain toxicity in renal epithelial cells, proximal tubular cells (PTCs) of different origin. Weinvestigated the relative cytotoxicity in cancer cells (A-498) and papilloma virus-transformedPTCs (HK-2) as well as to primary human PTCs (hPTC) to valida
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Old, Sally Louise. "Focal lesions in toxicity studies : methods and models." Thesis, De Montfort University, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.391200.

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Thanh, Nguyen Thi Kim. "Renal lipid changes in response to chemical insults." Thesis, University of East London, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.246194.

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Sword, Corinna Jane. "An in vitro study of aminoglycoside toxicity using established renal cell-lines." Thesis, University of Newcastle Upon Tyne, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.244557.

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Morley, Timothy James. "Mechanisms of renal glomerular toxicity of an N-hydroxyurea 5-lipoxygenase inhibitor." Thesis, University of Aberdeen, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.394534.

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The N-hydroxyurea derivative, ((<I>E</I>)-<I>N</I>-{3-[3-(4-fluorophenoxy) phenyl]-1-(<I>R,S</I>)-methylprop-2-enyl}-<I>N</I>-hydroxyurea), (70C), was being developed as a 5-lipoxygenase inhibitor for the treatment of asthma and was found cause severe glomerulopathy in the rat (Read <I>et al</I>, 1995). The lesion appeared to be of greater severity in female rats compared with male rats. The earliest changes detected in the kidney by transmission electron microscopy were noted in the glomeruli, in which the visceral cells appeared enlarged and showed varying degrees of foot process loss. In th
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McGoldrick, Trevor A. "C-S lyase-mediated toxicity in primary cultures of proximal tubular cells." Thesis, University of Aberdeen, 2000. http://digitool.abdn.ac.uk/R?func=search-advanced-go&find_code1=WSN&request1=AAIU602010.

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Halogenated alkenes are a group of commercially important chemicals. For example tetrafluoroethylene is the monomer used for the production of poly- tetrafluoroethylene, hexachloro-1:3-butadiene is a by-product from the manufacture of chlorinated solvents and perchloroethylene is widely used as a dry cleaning agent. Due to possible exposure to haloalkenes and the nephrotoxicity observed in animal studies, concern has been expressed for the potential of these compounds to cause toxicity to man. Animal studies have shown that these compounds undergo inter-organ metabolism and are bioactivated by
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de, Barros Pereira I. M. "Investigation of biomarkers of hepatic and renal toxicity in the Han Wistar rat." Thesis, University College London (University of London), 2014. http://discovery.ucl.ac.uk/1435551/.

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The aim of this project was to identify urinary markers of hepatic and renal toxicity in the male Hanover-Wistar rat; acute and chronic injury models were developed by administration of CCl4. Nephrotoxicity was induced by administration of HCBD. In an acute dose study, CCl4-induced nephrotoxicity occurred above 2.0 mL/kg CCl4. To avoid kidney injury, 2.0 mL/kg CCl4 was chosen as the optimal dose. 1H NMR revealed many changes to the urinary metabolome following CCl4-induced liver injury including an increase in the resonances of taurine, creatine and formate and a decrease in hippurate and crea
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Secker, Philipp Fabian [Verfasser]. "Functional approaches to study renal and mitochondrial toxicity in vitro / Philipp Fabian Secker." Konstanz : KOPS Universität Konstanz, 2018. http://d-nb.info/1217597700/34.

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McLaren, John. "Human renal proximal tubular cells, in suspension and primary culture, as in vitro models of drug-induced nephrotoxicity." Thesis, University of Aberdeen, 1992. http://digitool.abdn.ac.uk/R?func=search-advanced-go&find_code1=WSN&request1=AAIU545620.

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The kidney is the target for a wide variety of chemical agents, including heavy metals, haloalkenes, analgesics and antibiotics. The functional and metabolic characteristics of the proximal tubule (PT) predispose it as the primary site for xenobiotic damage. The aim of this study was to isolate and characterise human and rat PT cells in suspension and primary culture for use as defined models to investigate drug-induced PT cell damage in vitro . A second aim was to compare the response of human and rat systems to known nephrotoxins. Human and rat PT cells (90&'37 viable) were isolated from kid
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Sousa, Fabiola Carine Monteiro de. "Efeito renal do veneno da Brothrops erythromelas e bloqueio induzido pelo fator antibotrÃpico do Didelphis marsupialis." Universidade Federal do CearÃ, 2004. http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=269.

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CoordenaÃÃo de AperfeiÃoamento de Pessoal de NÃvel Superior<br>Some animals present natural resistance to the effects of snake venoms that can be explained by the presence of neutralizing factors in their blood serum. The resistance of South American Didelphis marsupialis, against crotalid venoms, especially of the genus Bothrops, of utmost medical importance in Brazil, has been object of investigation in the last few years. Bothrops erythromelas, known as âjararaca-da-secaâ or âjararaca-malha-de-cascavelâ is responsible for a great deal of snakebites in Northeastern Brazil. The venom of this
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Books on the topic "Renal toxicity"

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S, Goldstein Robin, ed. Mechanisms of injury in renal disease and toxicity. CRC Press, 1994.

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Redegeld, Franciscus Antonius Maria. Hepatic and renal toxicity of xenobiotics: The role of metabolism and transport. s.n.], 1989.

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P, Baetcke Karl, and United States. Environmental Protection Agency. Risk Assessment Forum., eds. Alpha[2u]-globulin: Association with chemically induced renal toxicity and neoplasia in the male rat. The Forum, 1992.

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P, Baetcke Karl, and United States. Environmental Protection Agency. Risk Assessment Forum., eds. Alpha[2u]-globulin: Association with chemically induced renal toxicity and neoplasia in the male rat. The Forum, 1992.

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P, Baetcke Karl, and United States. Environmental Protection Agency. Risk Assessment Forum, eds. Alpha[2u]-globulin: Association with chemically induced renal toxicity and neoplasia in the male rat. The Forum, 1992.

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P, Baetcke Karl, and United States. Environmental Protection Agency. Risk Assessment Forum., eds. Alpha[2u]-globulin: Association with chemically induced renal toxicity and neoplasia in the male rat. The Forum, 1992.

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P, Baetcke Karl, and United States. Environmental Protection Agency. Risk Assessment Forum., eds. Alpha[2u]-globulin: Association with chemically induced renal toxicity and neoplasia in the male rat. The Forum, 1992.

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P, Boetche Karl, and United States. Environmental Protection Agency. Risk Assessment Forum, eds. Alpha[2u]-globulin: Association with chemically induced renal toxicity and neoplasia in the male rat. The Forum, 1992.

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Handelsman, Harry. Hemoperfusion in conjunction with deferoxamine for the treatment of aluminum toxicity or iron overload in patients with end-stage renal disease. National Center for Health Services Research and Health Care Technology Assessment, U.S. Dept. of Health and Human Services, Public Health Service, 1987.

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Handelsman, Harry. Hemoperfusion in conjunction with deferoxamine for the treatment of aluminum toxicity or iron overload in patients with end-stage renal disease. National Center for Health Services Research and Health Care Technology Assessment, U.S. Dept. of Health and Human Services, Public Health Service, 1987.

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Book chapters on the topic "Renal toxicity"

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Abdelrahim, Maen, and Ala Abudayyeh. "Renal Toxicity." In Advances in Experimental Medicine and Biology. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-41008-7_16.

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Rainsford, K. D. "Renal Toxicity." In Ibuprofen: Pharmacology, Therapeutics and Side Effects. Springer Basel, 2012. http://dx.doi.org/10.1007/978-3-0348-0496-7_9.

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Abdelrahim, Maen, and Ala Abudayyeh. "Renal Toxicity." In Advances in Experimental Medicine and Biology. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-79308-1_16.

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Vanholder, R., A. Schoots, and S. Ringoir. "Uremic Toxicity." In Replacement of Renal Function by Dialysis. Springer Netherlands, 1989. http://dx.doi.org/10.1007/978-94-009-1087-4_2.

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Vanholder, Raymond Camille, Rita De Smet, and Norbert Hendrik Lameire. "Uremic toxicity." In Replacement of Renal Function by Dialysis. Springer Netherlands, 2004. http://dx.doi.org/10.1007/978-1-4020-2275-3_2.

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Nasir, K., M. Khan, Gordon C. Hard, and Zaher A. Radi. "Chapter 20. Renal Toxicity." In Drug Discovery. Royal Society of Chemistry, 2011. http://dx.doi.org/10.1039/9781849733045-00499.

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Sedman, Aileen B., and Gordon L. Klein. "Aluminum toxicity in childhood." In Aluminum and renal failure. Springer Netherlands, 1990. http://dx.doi.org/10.1007/978-94-009-1868-9_21.

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Blumenthal, Norman C., and John C. Grew. "Experimental models of aluminum toxicity." In Aluminum and renal failure. Springer Netherlands, 1990. http://dx.doi.org/10.1007/978-94-009-1868-9_13.

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Cannata Andia, Jorge B., and Jose B. Diaz Lopez. "The diagnosis of aluminium toxicity." In Aluminum and renal failure. Springer Netherlands, 1990. http://dx.doi.org/10.1007/978-94-009-1868-9_23.

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Tomson, Charles R. V., and Michael K. Ward. "Aluminium Toxicity in Renal Failure." In Replacement of Renal Function by Dialysis. Springer Netherlands, 1989. http://dx.doi.org/10.1007/978-94-009-1087-4_50.

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Conference papers on the topic "Renal toxicity"

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Das, Mayukh, and Wolf-Tilo Balke. "Toximatics: Towards Understanding Toxicity in Real-Life Social Situations." In Proceedings of the 25th Annual Meeting of the Special Interest Group on Discourse and Dialogue. Association for Computational Linguistics, 2024. http://dx.doi.org/10.18653/v1/2024.sigdial-1.65.

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Amutha, S., Golla Venkata Rakesh, Bommu Lila Vira Raghava Reddy, B.Jagadeesh, G. Siva Kumar, and Kothai Ganesan. "Real-Time Comment Filtering: A Chrome Extension for Toxicity Reduction on Facebook." In 2025 Third International Conference on Augmented Intelligence and Sustainable Systems (ICAISS). IEEE, 2025. https://doi.org/10.1109/icaiss61471.2025.11042197.

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Ying, D. D., and K. Wong. "Renal Replacement Therapy to Correct Refractory Hypokalemia From Hydroxychloroquine Toxicity." In American Thoracic Society 2023 International Conference, May 19-24, 2023 - Washington, DC. American Thoracic Society, 2023. http://dx.doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a3491.

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Labate, L., C. Marelli, F. Rismondo, et al. "P-179 Renal toxicity in a cohort of PrEP users." In Abstracts from the 16° Italian Conference on AIDS and Antiviral Research. BMJ Publishing Group Ltd, 2024. http://dx.doi.org/10.1136/sextrans-icar-2024.242.

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Magdalena Pérez, A., J. Peña Hernández, A. Santos Fagundo, et al. "5PSQ-103 Vancomycin-induced renal toxicity through therapeutic drug monitoring in daily practice." In 28th EAHP Congress, Bordeaux, France, 20-21-22 March 2024. British Medical Journal Publishing Group, 2024. http://dx.doi.org/10.1136/ejhpharm-2024-eahp.437.

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Fatima, S., N. Sheikh, and A. Tayyeb. "Investigation of hepatic and renal toxicity induced by omeprazole in CCl4 injury mouse model." In 35. Jahrestagung der Deutschen Arbeitsgemeinschaft zum Studium der Leber. Georg Thieme Verlag KG, 2019. http://dx.doi.org/10.1055/s-0038-1677070.

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"Evaluation of renal toxicity in male albino rats Rattus rattus after silver nanoparticles exposure." In 4TH INTERNATIONAL CONFERENCE ON BIOLOGICAL & HEALTH SCIENCES. Cihan University - Erbil, 2022. http://dx.doi.org/10.24086/biohs2022/paper.663.

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Sanchez, B., JM Caro Teller, I. Gonzalez Barrios, et al. "5PSQ-053 Influence of augmented renal clearance in the lower incidence of linezolid-related haematological toxicity." In 26th EAHP Congress, Hospital pharmacists – changing roles in a changing world, 23–25 March 2022. British Medical Journal Publishing Group, 2022. http://dx.doi.org/10.1136/ejhpharm-2022-eahp.284.

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Krens, Stefanie D., Wim van Boxtel, Maike J. Uijen, et al. "Abstract 1363: Exposure-toxicity analysis of cabozantinib in patients with salivary gland cancer and renal cell cancer." In Proceedings: AACR Annual Meeting 2021; April 10-15, 2021 and May 17-21, 2021; Philadelphia, PA. American Association for Cancer Research, 2021. http://dx.doi.org/10.1158/1538-7445.am2021-1363.

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Kaewpaiboon, Sunisa, Titpawan Nakpheng, and Teerapol Srichana. "Biocompatibility of Polymyxin B Sulfate Based on Sodium Deoxycholate Sulfate Formulations with Kidney Cell Lines, Macrophage Cells, and Red Blood Cells." In 5th International Conference and Exhibition on Pharmaceutical Sciences and Technology 2022. Trans Tech Publications Ltd, 2022. http://dx.doi.org/10.4028/p-7490x3.

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Antibiotic-resistant has emerged without new drug challenges. Polymyxin B (PMB) was the last resort therapy for multiple-drug resistant Gram-negative bacteria. However, the toxicity of PMB including nephrotoxicity (61%) and neurotoxicity (7%) was dose-limitation. PMB-based sodium deoxycholate sulfate (SDCS) formulations were prepared in the 2-different mole ratios of SDCS to PMB (5:1 and 10:1). Particle size, zeta-potential, and drug content were evaluated. The biocompatibility of PMB formulations was investigated with normal human primary renal proximal tubule epithelial cells (PCS-400-010),
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Reports on the topic "Renal toxicity"

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Chen, Xiangyu, Zhunan Xu, Changgui Wu, Lijun Xie, Pengyu Wang, and Xiaoqiang Liu. Efficacy and toxicity of immune checkpoint inhibitors combination therapy for advanced renal cell carcinoma: A systematic review and network meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2024. http://dx.doi.org/10.37766/inplasy2024.1.0078.

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Avihingsanon, Yingyos, Jongkonnee Wongpiyabovorn, and Nattiya Hirankarn. Biomarker discovery in systemic lupus erythematosus: genome-methylation approaches : Research report. Chulalongkorn University, 2010. https://doi.org/10.58837/chula.res.2010.15.

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Discovery of novel biomarkers in lupus nephritis Biomarkers are needed for making diagnosis and prognosis. In lupus nephritis, conventional tests like urinalysis or serum creatinine remain inadequate for patient care. In this proposal, we focused on non-invasive tools like blood and urine mRNAs or proteins. We chose candidate genes involving regulatory T-cell, B-lymphocyte signatures or vascular protective factors. Expression of regulatory cell signature (FOXP3) in peripheral blood mononuclear cells is associated with activity of lupus nephritis. We found FOXP3 mRNA levels in PBMCs from patien
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Babrauskas, Vytenis. The Role of bench-scale test data in assessing real-scale fire toxicity. National Bureau of Standards, 1990. http://dx.doi.org/10.6028/nist.tn.1284.

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Parikh, Romil R., Alexander Troester, Bronwyn Southwell, et al. Treatment of Stages I–III Squamous Cell Anal Cancer: A Systematic Review. Agency for Healthcare Research and Quality (AHRQ), 2024. http://dx.doi.org/10.23970/ahrqepccer273.

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Objectives. To evaluate the comparative effectiveness and harms of initial treatment and posttreatment surveillance strategies for stages I–III squamous cell anal cancer. Data sources. MEDLINE®, Embase®, Cochrane Register of Controlled Trials, and ClinicalTrials.gov from January 2000 through March 2024; reference lists of systematic reviews and included studies; and a Federal Register notice. Review methods. Using predefined criteria and dual review, we selected randomized controlled trials (RCTs) and nonrandomized studies of interventions (NRSIs) comparing strategies for chemotherapy, radiati
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Steele, Dale W., Gaelen P. Adam, Ian J. Saldanha, et al. Management of Postpartum Hypertensive Disorders of Pregnancy. Agency for Healthcare Research and Quality (AHRQ), 2023. http://dx.doi.org/10.23970/ahrqepccer263.

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Background. Hypertensive disorders of pregnancy (HDP) are increasingly common and have important implications for maternal health, healthcare utilization, and health disparities. There is limited evidence to support best management of postpartum individuals with HDP, including home blood pressure (BP) monitoring (HBPM) and choice of antihypertensive agents. For patients experiencing preeclampsia with severe features, there is robust evidence supporting delivery of the infant and treatment with magnesium sulfate (MgSO4). However, MgSO4 may cause unpleasant side effects and, less commonly, toxic
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Committee on Toxicology. COT FSA PBPK for Regulators Workshop Report 2021. Food Standards Agency, 2024. http://dx.doi.org/10.46756/sci.fsa.tyy821.

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The future of food safety assessment in the UK depends on the Food Standards Agency’s (FSA) adaptability and flexibility in responding to and adopting the accelerating developments in science and technology. The Tox21 approach is an example of one recent advancement in the development of alternative toxicity testing approaches and computer modelling strategies for the evaluation of hazard and exposure (New Approach Methodologies (NAMs). A key aspect is the ability to link active concentrations in vitro to likely concentrations in vivo, for which physiologically based pharmacokinetic (PBPK) mod
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