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Relevant bibliographies by topics / Replicative recombination

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Academic literature on the topic 'Replicative recombination'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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Journal articles on the topic "Replicative recombination"

1

Weerasooriya, Savithri, Katherine A. DiScipio, Anthar S. Darwish, Ping Bai, and Sandra K. Weller. "Herpes simplex virus 1 ICP8 mutant lacking annealing activity is deficient for viral DNA replication." Proceedings of the National Academy of Sciences 116, no. 3 (2018): 1033–42. http://dx.doi.org/10.1073/pnas.1817642116.

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Most DNA viruses that use recombination-dependent mechanisms to replicate their DNA encode a single-strand annealing protein (SSAP). The herpes simplex virus (HSV) single-strand DNA binding protein (SSB), ICP8, is the central player in all stages of DNA replication. ICP8 is a classical replicative SSB and interacts physically and/or functionally with the other viral replication proteins. Additionally, ICP8 can promote efficient annealing of complementary ssDNA and is thus considered to be a member of the SSAP family. The role of annealing during HSV infection has been difficult to assess in pa

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Gallei, Andreas, Alexander Pankraz, Heinz-Jürgen Thiel, and Paul Becher. "RNA Recombination In Vivo in the Absence of Viral Replication." Journal of Virology 78, no. 12 (2004): 6271–81. http://dx.doi.org/10.1128/jvi.78.12.6271-6281.2004.

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ABSTRACT To study fundamental aspects of RNA recombination, an in vivo RNA recombination system was established. This system allowed the efficient generation of recombinant cytopathogenic pestiviruses after transfection of synthetic, nonreplicatable, subgenomic transcripts in cells infected with a replicating noncytopathogenic virus. Studies addressing the interplay between RNA recombination and replication revealed that cotransfection of noninfected cells with various pairs of nonreplicatable RNA derivatives also led to the emergence of recombinant viral genomes. Remarkably, homologous and no

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Yonesaki, T. "Involvement of a replicative DNA helicase of bacteriophage T4 in DNA recombination." Genetics 138, no. 2 (1994): 247–52. http://dx.doi.org/10.1093/genetics/138.2.247.

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Abstract Bacteriophage T4 gene 41 encodes a replicative DNA helicase that is a subunit of the primosome which is essential for lagging-strand DNA synthesis. A mutation, rrh, was generated and selected in the helicase gene on the basis of limited DNA replication that ceases early. The survival of ultraviolet-irradiated phage and the frequency of genetic recombination are reduced by rrh. In addition, rrh diminishes the production of concatemeric DNA. These results strongly suggest that the gene 41 replicative helicase participates in DNA recombination.

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Hayashi, Yasuyuki, Yoshiyuki Kitamura, Mayumi Nakanishi, and Katsuro Koike. "The Binding Site of Transcription Factor YY1 Is Required for Intramolecular Recombination between Terminally Repeated Sequences of Linear Replicative Hepatitis B Virus DNA." Journal of Virology 74, no. 20 (2000): 9471–78. http://dx.doi.org/10.1128/jvi.74.20.9471-9478.2000.

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ABSTRACT In the replication cycle of hepadnavirus DNA, the double-stranded linear form of viral DNA is generated as a minor replicative intermediate, which is efficiently converted to covalently closed circular DNA (cccDNA) by intramolecular recombination (W. Yang and J. Summers, J. Virol. 69:4029–4036, 1995). We previously found a binding site of transcription factor Yin and Yang 1 (YY1) in one terminal region of the double-stranded linear replicative hepatitis B virus (HBV) DNA (M. Nakanishi-Matsui, Y. Hayashi, Y. Kitamura, and K. Koike, J. Virol. 74:5562–5568, 2000). However, it is not know

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Tsai, Yun-Luen, Shun-Fu Tseng, Shih-Husan Chang, Chuan-Chuan Lin, and Shu-Chun Teng. "Involvement of Replicative Polymerases, Tel1p, Mec1p, Cdc13p, and the Ku Complex in Telomere-Telomere Recombination." Molecular and Cellular Biology 22, no. 16 (2002): 5679–87. http://dx.doi.org/10.1128/mcb.22.16.5679-5687.2002.

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ABSTRACT Telomere maintenance is required for chromosome stability, and telomeres are typically replicated by the action of the reverse transcriptase telomerase. In both tumor and yeast cells that lack telomerase, telomeres are maintained by an alternative recombination mechanism. Genetic studies have led to the identification of DNA polymerases, cell cycle checkpoint proteins, and telomere binding proteins involved in the telomerase pathway. However, how these proteins affect telomere-telomere recombination has not been identified to date. Using an assay to trace the in vivo recombinational p

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Gómez-González, Belén, Irene Felipe-Abrio, and Andrés Aguilera. "The S-Phase Checkpoint Is Required To Respond to R-Loops Accumulated in THO Mutants." Molecular and Cellular Biology 29, no. 19 (2009): 5203–13. http://dx.doi.org/10.1128/mcb.00402-09.

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ABSTRACT Cotranscriptional R-loops are formed in yeast mutants of the THO complex, which functions at the interface between transcription and mRNA export. Despite the relevance of R-loops in transcription-associated recombination, the mechanisms by which they trigger recombination are still elusive. In order to understand how R-loops compromise genome stability, we have analyzed the genetic interaction of THO with 26 genes involved in replication, S-phase checkpoint, DNA repair, and chromatin remodeling. We found a synthetic growth defect in double null mutants of THO and S-phase checkpoint fa

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Dudas, Kathleen C., and Kenneth N. Kreuzer. "UvsW Protein Regulates Bacteriophage T4 Origin-Dependent Replication by Unwinding R-Loops." Molecular and Cellular Biology 21, no. 8 (2001): 2706–15. http://dx.doi.org/10.1128/mcb.21.8.2706-2715.2001.

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ABSTRACT The UvsW protein of bacteriophage T4 is involved in many aspects of phage DNA metabolism, including repair, recombination, and recombination-dependent replication. UvsW has also been implicated in the repression of origin-dependent replication at late times of infection, when UvsW is normally synthesized. Two well-characterized T4 origins, ori(uvsY) andori(34), are believed to initiate replication through an R-loop mechanism. Here we provide both in vivo and in vitro evidence that UvsW is an RNA-DNA helicase that catalyzes the dissociation of RNA from origin R-loops. Two-dimensional g

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Evans, David Hugh. "Poxvirus Recombination." Pathogens 11, no. 8 (2022): 896. http://dx.doi.org/10.3390/pathogens11080896.

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Genetic recombination is used as a tool for modifying the composition of poxvirus genomes in both discovery and applied research. This review documents the history behind the development of these tools as well as what has been learned about the processes that catalyze virus recombination and the links between it and DNA replication and repair. The study of poxvirus recombination extends back to the 1930s with the discovery that one virus can reactivate another by a process later shown to generate recombinants. In the years that followed it was shown that recombinants can be produced in virus-b

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Prado, Félix. "Homologous Recombination: To Fork and Beyond." Genes 9, no. 12 (2018): 603. http://dx.doi.org/10.3390/genes9120603.

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Accurate completion of genome duplication is threatened by multiple factors that hamper the advance and stability of the replication forks. Cells need to tolerate many of these blocking lesions to timely complete DNA replication, postponing their repair for later. This process of lesion bypass during DNA damage tolerance can lead to the accumulation of single-strand DNA (ssDNA) fragments behind the fork, which have to be filled in before chromosome segregation. Homologous recombination plays essential roles both at and behind the fork, through fork protection/lesion bypass and post-replicative

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Lehmann, Carl P., Alberto Jiménez-Martín, Dana Branzei, and José Antonio Tercero. "Prevention of unwanted recombination at damaged replication forks." Current Genetics 66, no. 6 (2020): 1045–51. http://dx.doi.org/10.1007/s00294-020-01095-7.

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Abstract Homologous recombination is essential for the maintenance of genome integrity but must be strictly controlled to avoid dangerous outcomes that produce the opposite effect, genomic instability. During unperturbed chromosome replication, recombination is globally inhibited at ongoing DNA replication forks, which helps to prevent deleterious genomic rearrangements. This inhibition is carried out by Srs2, a helicase that binds to SUMOylated PCNA and has an anti-recombinogenic function at replication forks. However, at damaged stalled forks, Srs2 is counteracted and DNA lesion bypass can b

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Dissertations / Theses on the topic "Replicative recombination"

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Wagner, Tina [Verfasser]. "Telomere folding in S. cerevisiae depends on chromatin modifiers and recombination factors and is lost during replicative senescence / Tina Wagner." Mainz : Universitätsbibliothek der Johannes Gutenberg-Universität Mainz, 2020. http://d-nb.info/1224896106/34.

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Magdalou, Indiana. "Réponses post-réplicatives au stress réplicatif chronique faible ou endogène, chez les mammifères." Thesis, Paris 11, 2014. http://www.theses.fr/2014PA112389/document.

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La réplication de l’ADN est un phénomène physiologique essentiel à la transmission du patrimoine génétique mais est aussi une source importante de stress endogène. Le stress réplicatif peut conduire à une instabilité génomique et a été mis en évidence à une étape très précoce du développement tumoral et de la sénescence. La recombinaison homologue (RH) est un processus de réparation qui permet la prise en prise en charge du stress réplicatif. De ce fait, un défaut de RH devrait permettre de révéler les stress réplicatifs endogènes. Ainsi, une progression ralentie des fourches de réplication a

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Motamedi, Mohammad Reza. "RecBCD-mediated replication and recombination in Escherichia coli." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape2/PQDD_0013/NQ59638.pdf.

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Lundin, Cecilia. "Homologous recombination at replication forks in mammalian cells /." Stockholm : Institutionen för genetik, mikrobiologi och toxikologi, Univ, 2004. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-207.

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Kumari, Anuradha. "Recombination and DNA intermediates at stalled replication forks." Thesis, University of Sheffield, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.412791.

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White, Martin A. "Replication, recombination and chromosome segregation in Escherichia coli." Thesis, University of Edinburgh, 2010. http://hdl.handle.net/1842/4088.

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SbcCD has been shown to cleave a DNA hairpin formed by a palindromic DNA sequence on the lagging strand template of the E. coli chromosome. This activity was exploited to create a unique system for inducing a single site-specific DNA double-strand break (DSB) once per replication cycle. First, this work shows that the SOS response induced by this DSB is only essential for viability following multiple cycles of cleavage and repair. Next, the SOS-inducible inhibitor of cell division SfiA is shown to be dispensable for survival, despite demonstrating that cleavage of the palindrome causes both an

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Jordan, Christian. "Helicase-SSB Interactions In Recombination-Dependent DNA Repair and Replication." ScholarWorks @ UVM, 2014. http://scholarworks.uvm.edu/graddis/270.

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Dda, one of three helicases encoded by bacteriophage T4, has been well- characterized biochemically but its biological role remains unclear. It is thought to be involved in origin-dependent replication, recombination-dependent replication, anti- recombination, recombination repair, as well as in replication fork progression past template-bound nucleosomes and RNA polymerase. One of the proteins that most strongly interacts with Dda, Gp32, is the only single-stranded DNA binding protein (SSB) encoded by T4, is essential for DNA replication, recombination, and repair. Previous studies have shown

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McCreary, Ronald Patrick. "Recombination-dependent DNA replication in bacteriophage T4: An evolutionary study." Diss., The University of Arizona, 1990. http://hdl.handle.net/10150/185267.

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Genetic recombination is an ubiquitious process in living organisms and is one of the most elaborate activities that DNA undergoes. As such, the recombination process potentially interacts with all of the major metabolic events involving DNA. This study examined one of these interactions, specifically that occuring between recombination and DNA replication in phage T4. This interaction was investigated from both the mechanisitic and evolutionary viewpoints. In phage and bacteria, the central reactions of homologous recombination are those of homologous pairing and strand insertion. These react

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Weng, Ziming. "Replication and recombination of the Red clover necrotic mosaic virus." Diss., The University of Arizona, 2002. http://hdl.handle.net/10150/280079.

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In this study, Red clover necrotic mosaic virus (RCNMV) was used to better understand the functions of replication proteins and to identify the terminal promoter element involved in viral replication. RCNMV genome contains two positive-sense, single-stranded RNAs. RNA-1 encodes two proteins essential for viral replication: p27 and p88. p88 is a fusion protein containing p27 at its N terminus and RNA dependent RNA polymerase motifs at its C-terminal domain. The function of p27 is not known. In this work, studies of RNA-1 chimerical clones between a highly infectious clone and a poorly infectiou

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Tsang, Ellen. "Interplay between checkpoints and recombination at sites of replication fork arrest." Thesis, University of Sussex, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.488568.

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Books on the topic "Replicative recombination"

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Hanaoka, Fumio, and Kaoru Sugasawa, eds. DNA Replication, Recombination, and Repair. Springer Japan, 2016. http://dx.doi.org/10.1007/978-4-431-55873-6.

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Kuzminov, Andrei. Recombinational repair of DNA damage. Chapman & Hall, 1996.

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R, Lindahl T., West S. C, and Royal Society (Great Britain), eds. DNA repair and recombination. Chapman & Hall, in association with the Royal Society, 1995.

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E, Gottesman Max, and Vogel Henry J. 1920-, eds. Mechanisms of eukaryotic DNA recombination. Academic Press, 1992.

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Roger, McMacken, and Kelly Thomas J. 1941-, eds. DNA replication and recombination: Proceedings of a UCLA symposium held at Park City, Utah, March 16-23, 1986. A.R. Liss, 1987.

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UCLA, Symposium on Molecular Mechanisms in DNA Replication and Recombination (1989 Keystone Colo ). Molecular mechanisms in DNA replication and recombination: Proceedings of a UCLA Symposium held at Keystone, Colorado, March 27-April 3, 1989. Wiely-Liss, 1990.

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E, Krebs Jocelyn, Goldstein Elliott S, Kilpatrick Stephen T, Lewin Benjamin, and Lewin Benjamin, eds. Lewin's essential genes. 2nd ed. Jones and Bartlett Publishers, 2009.

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C, Richardson Charles, and Lehman I. Robert, eds. Molecular mechanisms in DNA replication and recombination: Proceedings of a UCLA Symposium held at Keystone, Colorado, March 27-April 3, 1989. Wiley-Liss, 1990.

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9

Lindahl, T. R., and S. C. West. DNA Repair and Recombination. Springer, 2011.

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Hanaoka, Fumio, and Kaoru Sugasawa. DNA Replication, Recombination, and Repair: Molecular Mechanisms and Pathology. Springer London, Limited, 2016.

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Book chapters on the topic "Replicative recombination"

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Young, C. S. H. "Homologous Recombination in the Replicative Cycle of Adenoviruses and Its Relationship to DNA Replication." In Current Topics in Microbiology and Immunology. Springer Berlin Heidelberg, 1995. http://dx.doi.org/10.1007/978-3-642-79499-5_4.

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Branzei, Dana, and Marco Foiani. "Replication forks and replication checkpoints in repair." In Molecular Genetics of Recombination. Springer Berlin Heidelberg, 2007. http://dx.doi.org/10.1007/978-3-540-71021-9_7.

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Osia, Beth, Rajula Elango, Juraj Kramara, Steven A. Roberts, and Anna Malkova. "Investigation of Break-Induced Replication in Yeast." In Homologous Recombination. Springer US, 2020. http://dx.doi.org/10.1007/978-1-0716-0644-5_22.

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Willis, Nicholas A., and Ralph Scully. "Measurement of Homologous Recombination at Stalled Mammalian Replication Forks." In Homologous Recombination. Springer US, 2020. http://dx.doi.org/10.1007/978-1-0716-0644-5_23.

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Whelan, Donna R., and Eli Rothenberg. "Super-Resolution Imaging of Homologous Recombination Repair at Collapsed Replication Forks." In Homologous Recombination. Springer US, 2020. http://dx.doi.org/10.1007/978-1-0716-0644-5_24.

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Sebesta, Marek, and Lumir Krejci. "Mechanism of Homologous Recombination." In DNA Replication, Recombination, and Repair. Springer Japan, 2016. http://dx.doi.org/10.1007/978-4-431-55873-6_4.

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Thacker, Drew, and Scott Keeney. "Homologous Recombination During Meiosis." In DNA Replication, Recombination, and Repair. Springer Japan, 2016. http://dx.doi.org/10.1007/978-4-431-55873-6_6.

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Araki, Hiroyuki. "Molecular Mechanism of DNA Replication." In DNA Replication, Recombination, and Repair. Springer Japan, 2016. http://dx.doi.org/10.1007/978-4-431-55873-6_1.

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Kobayashi, Takehiko. "Genome Instability of Repetitive Sequence: Lesson from the Ribosomal RNA Gene Repeat." In DNA Replication, Recombination, and Repair. Springer Japan, 2016. http://dx.doi.org/10.1007/978-4-431-55873-6_10.

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Masuda, Yuji, Fumio Hanaoka, and Chikahide Masutani. "Translesion DNA Synthesis and Damage Tolerance Pathways." In DNA Replication, Recombination, and Repair. Springer Japan, 2016. http://dx.doi.org/10.1007/978-4-431-55873-6_11.

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Conference papers on the topic "Replicative recombination"

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Batyuchenko, A. V., A. A. Shishova, and A. V. Dereventsova. "POSSIBLE ROLE OF ALTERNATIVE SPLICING ENZYMES IN NON-REPLICATIVE RNA RECOMBINATION." In X Международная конференция молодых ученых: биоинформатиков, биотехнологов, биофизиков, вирусологов и молекулярных биологов — 2023. Novosibirsk State University, 2023. http://dx.doi.org/10.25205/978-5-4437-1526-1-230.

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RNA recombination is an important and one of the main mechanisms of RNA virus evolution. Two mechanisms of this process are currently known [2, 3]. A recombinant RNA molecule can be formed by replicative matrix switching [1, 2]. There is also increasing information about another non-replicative mechanism of viral RNA recombination [4]. However, the role of cellular factors in this process is still under investigation [2].

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Scully, Ralph, and Nicholas A. Willis. "Abstract SY34-03: Recombination functions of BRCA1 and BRCA2 at stalled replication forks." In Proceedings: AACR 107th Annual Meeting 2016; April 16-20, 2016; New Orleans, LA. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/1538-7445.am2016-sy34-03.

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Reports on the topic "Replicative recombination"

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Morris, T. J., and A. O. Jackson. Tomato bushy stunt virus and DI RNAs as a model for studying mechanisms of RNA virus replication, pathogenicity and recombination. Final technical report for 1994--1997. Office of Scientific and Technical Information (OSTI), 1997. http://dx.doi.org/10.2172/353366.

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Sawicka, D., M. de Carvalho-Kavanagh, D. Barsky, and C. Venclovas. FY05 LDRD Fianl Report Investigation of AAA+ protein machines that participate in DNA replication, recombination, and in response to DNA damage LDRD Project Tracking Code: 04-LW-049. Office of Scientific and Technical Information (OSTI), 2006. http://dx.doi.org/10.2172/897962.

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