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Journal articles on the topic 'Rotavirus gastroenteritis'

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1

Enweronu-Laryea, Christabel C., Kwamena W. C. Sagoe, Hope Glover-Addy, Richard H. Asmah, Julius A. Mingle, and George E. Armah. "Prevalence of severe acute rotavirus gastroenteritis and intussusceptions in Ghanaian children under 5 years of age." Journal of Infection in Developing Countries 6, no. 02 (2011): 148–55. http://dx.doi.org/10.3855/jidc.1667.

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Introduction: Vaccination is the most effective preventive strategy against rotavirus disease. Regional differences in prevalent rotavirus genotypes may affect vaccine efficacy. Pre-vaccine surveillance for burden of rotavirus disease, prevalent rotavirus genotypes, and association between rotavirus disease and intussusceptions helps in monitoring the impact of vaccination. Methodology: A prospective study was conducted from January 2008 to December 2009 in children younger than five years hospitalized for longer than 24 hours with acute gastroenteritis. Data on confirmed cases of intussuscept
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2

Lin, Che-Liang, Shou-Chien Chen, Shyun-Yeu Liu, and Kow-Tong Chen. "Disease Caused by Rotavirus Infection." Open Virology Journal 8, no. 1 (2014): 14–19. http://dx.doi.org/10.2174/1874357901408010014.

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Although rotavirus vaccines are available, rotaviruses remain the major cause of childhood diarrheal disease worldwide. The Rotarix (GlaxoSmithKline Biologicals Rixensart, Belgium) and RotaTeq (Merck and Co., Inc. Whitehouse Station, New Jersey, USA) vaccines are effective for reducing the morbidity and mortality of rotavirus infection. This article aims to assess the epidemiology of rotaviral gastroenteritis and the efficacy and effectiveness of licensed rotavirus vaccines. This review concludes by presenting challenges in the field that require further exploration by and perspectives from ba
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Yamashiro, Yuichiro, Toshiaki Shimizu, Satoshi Oguchi, and Mitsuyoshi Sato. "Prostaglandins in the Plasma and Stool of Children with Rotavirus Gastroenteritis." Journal of Pediatric Gastroenterology and Nutrition 9, no. 3 (1989): 322–27. http://dx.doi.org/10.1002/j.1536-4801.1989.tb09877.x.

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To investigate whether prostaglandins (PGs) are involved in the mechanism of rotavirus diarrhea, PGE2 and PGF2a concentrations in the plasma and stool of children (21 and 16, respectively) with rotavirus gastroenteritis were measured and compared with those of their respective controls. The effect of aspirin on the diarrhea was also studied in 14 patients with rotavirus gastroenteritis. The PGE2 and PGF2a contents of both the plasma and the stool of patients with rotavinis gastroenteritis were significantly higher than in the plasma and stool of the control group. Furthermore, aspirin given by
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4

Weibel, Josef, H. Fred Clark, and Gerd G. Maul. "High-resolution analysis and probable non-viral origin of lattice structures found in rotavirus preparations." Proceedings, annual meeting, Electron Microscopy Society of America 48, no. 3 (1990): 604–5. http://dx.doi.org/10.1017/s0424820100160571.

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Acute gastroenteritis causes death in millions of cases, and many are due to viruses, mostly rotavirus. Through appropriate hygiene and health care, deaths from gastroenteritis have dropped considerably in the United States. Price and coworkers tested by electronmicroscopy of stool samples 537 specimens in 1988 and found 19% of them to contain viruses most commonly rotaviruses. The morphological criteria for the actual rotaviruses cannot be mistaken. However, they also used the appearance of the lattice structures to diagnose rotavirus infection. The same description of these lattice structure
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5

Maralihalli, Mahesh B., Kavan R. Deshpande, and Pallavi K. Deshpande. "Analysis of complete blood counts in rotaviral gastroenteritis with special emphasis on platelet indices." International Journal of Contemporary Pediatrics 6, no. 4 (2019): 1567. http://dx.doi.org/10.18203/2349-3291.ijcp20192756.

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Background: The objectives of this study was to analyze complete blood counts in rotaviral gastroenteritis with special emphasis on platelet indices.Methods: Children diagnosed as rotavirus gastroenteritis and healthy controls were enrolled in this study. Severity of acute gastroenteritis was classified into mild, moderate and severe grades using Vesikari score. Rotavirus was determined in fresh stool samples using rapid diagnostic rotavirus antigen test. Hemoglobin, leukocyte, neutrophil to lymphocyte percentage ratio, platelet counts, mean platelet volume (MPV), platelet distribution width (
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6

Babić, Tatjana, Biljana Miljković-Selimović, Dobrila Đorđević-Stanković, et al. "The incidence of rotavirus infection compared to bacterial infections in different age groups of pediatric patients with gastroenteritis." Sanitarno inženirstvo International Journal of Sanitary Engineering Research 13, no. 1 (2019): 39–52. http://dx.doi.org/10.2478/ijser-2019-0005.

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AbstractRotavirus is the important cause of acute gastroenteritis in pediatric patients. The aim of the present research was to determine the incidence of rotavirus infections in infants and children up to seven years of age in the town of Niš. Seasonal prevalence of rotavirus-associated acute gastroenteritis was also evaluated. An enzyme immunoassay (RIDASCREEN® Rotavirus; R-Biopharm AG, Darmstadt, Germany) was used to detect rotavirus in the stool specimens of 1,156 patients (newborns up to 7 years of age) presenting with gastroenteritis. Identification of bacteria and yeasts was performed b
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7

Pérez-Ortín, Raúl, Susana Vila-Vicent, Noelia Carmona-Vicente, Cristina Santiso-Bellón, Jesús Rodríguez-Díaz, and Javier Buesa. "Histo-Blood Group Antigens in Children with Symptomatic Rotavirus Infection." Viruses 11, no. 4 (2019): 339. http://dx.doi.org/10.3390/v11040339.

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Group A rotaviruses are a major cause of acute gastroenteritis in children. The diversity and unequal geographical prevalence of rotavirus genotypes have been linked to histo-blood group antigens (HBGAs) in different human populations. In order to evaluate the role of HBGAs in rotavirus infections in our population, secretor status (FUT2+), ABO blood group, and Lewis antigens were determined in children attended for rotavirus gastroenteritis in Valencia, Spain. During three consecutive years (2013–2015), stool and saliva samples were collected from 133 children with rotavirus infection. Infect
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8

Gundeslioglu, Özlem O., Recep Tekin, Saliha Cevik, Yılmaz Palancı, and Atilla Yazıcıoglu. "The effects of nosocomial rotavirus gastroenteritis on the length of hospital stay and cost." Journal of Infection in Developing Countries 10, no. 02 (2016): 163–67. http://dx.doi.org/10.3855/jidc.5591.

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Introduction: In this study, the goal was to evaluate the impact of nosocomial rotavirus gastroenteritis in pediatric patients by determining the incidence of nosocomial rotavirus gastroenteritis, the resulting duration of hospital stay, and direct cost. To our knowledge, this is the first study in Turkey that evaluates the impact of pediatric nosocomial rotavirus gastroenteritis on duration of hospital stay and calculates the direct cost. Methodology: Forty-nine patients who were diagnosed with nosocomial rotavirus gastroenteritis and hospitalized were included in the study. Nosocomial infect
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9

Gratacap-Cavallier, B., O. Genoulaz, K. Brengel-Pesce, et al. "Detection of Human and Animal Rotavirus Sequences in Drinking Water." Applied and Environmental Microbiology 66, no. 6 (2000): 2690–92. http://dx.doi.org/10.1128/aem.66.6.2690-2692.2000.

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ABSTRACT Reverse transcription-PCR analysis of drinking water in the homes of 56 children suffering from rotaviral gastroenteritis has shown the presence of the rotavirus genome in four samples. These strains were different from human rotaviruses detected in the children's feces, as determined by sequencing of the VP7-amplified fragments—three of them of animal origin (porcine or bovine) and one of human origin.
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10

Mahdi Mutlak, Qassim, Manal Khalid Abdulridha, and Laith M Abbas Al-Huseini. "Study the Distribution of Rotavirus Genotypes in Vaccinated and non Vaccinated Children in Babylon Province." Iraqi Journal of Pharmaceutical Sciences ( P-ISSN: 1683 - 3597 , E-ISSN : 2521 - 3512) 30, no. 2 (2021): 167–76. http://dx.doi.org/10.31351/vol30iss2pp167-176.

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Rotaviruses, a major cause of gastroenteritis in children worldwide accounts for around half a million deaths annually. Vaccine against the virus has been recommended by the WHO to be involved in the national immunization program.To evaluate the genetic characterization of rotavirus among children with acute gastroenteritis in Babylon province is warranted. Children complained of diarrhea with rotavirus infection detected in their stool were involved in the study. The age range was 10 months to 60 months and with retrogradechecking of rotavirus vaccine history. Rotavirus genotypes were detecte
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11

Sheridan, Sarah, Stephen Lambert, and Keith Grimwood. "Impact of rotavirus vaccination on childhood gastroenteriti." Microbiology Australia 33, no. 2 (2012): 56. http://dx.doi.org/10.1071/ma12056.

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Rotaviruses are the most common cause of severe childhood gastroenteritis worldwide. The recent development of safe and effective rotavirus vaccines means that the global health and economic burden of rotavirus disease can now be reduced.
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12

Bartlett, A. V., A. J. Bednarz-Prashad, H. L. DuPont, and L. K. Pickering. "Rotavirus Gastroenteritis." Annual Review of Medicine 38, no. 1 (1987): 399–415. http://dx.doi.org/10.1146/annurev.me.38.020187.002151.

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13

Leung, Alexander K. C., James D. Kellner, and H. Dele Davies. "Rotavirus gastroenteritis." Advances in Therapy 22, no. 5 (2005): 476–87. http://dx.doi.org/10.1007/bf02849868.

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14

Kovacs, Andrea. "Rotavirus Gastroenteritis." American Journal of Diseases of Children 141, no. 2 (1987): 161. http://dx.doi.org/10.1001/archpedi.1987.04460020051025.

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15

Kleshchuk, А. А., and Т. R. Kolotylo. "MANIFESTATIONS AND COMPLICATIONS OF ROTAVIRUS-POSITIVE GASTROENTERITIS AND ROTAVIRUS-NEGATIVE GASTROENTERITIS IN PRESCHOOL CHILDREN." Medical Science of Ukraine (MSU) 19, no. 1 (2023): 70–73. http://dx.doi.org/10.32345/2664-4738.1.2023.09.

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Background. The cumulative annual statistics of rotavirus-associated gastroenteritis are about 25 million outpatient visits, 2 million hospitalizations, and 180,000–450,000 deaths in children under 5 years of age.
 Aim: To analyze the manifestations and complications of rotavirus compared with non-rotavirus gastroenteritis in UK children.
 Materials and methods. A retrospective hospital-based case-control study was conducted at three sites in East London, Great Britain. Cases were children aged 1 month to 16 years who were diagnosed with acute gastroenteritis between June 1, 2011, an
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16

S. Abood, Wisam, S. A. Al-Juboury, and M. A. Al-Rodhan. "Prevalence and factors associated with rotavirus infection among infants admitted for diarrhea in the region of Mid Iraq." AL-QADISIYAH MEDICAL JOURNAL 10, no. 18 (2017): 24–28. http://dx.doi.org/10.28922/qmj.2014.10.18.24-28.

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Rotavirus is the most common cause of severe childhood diarrhea worldwide and of diarrheal mortality in developing countries. In Iraq, few studies and analysis were executed for evaluation of the extent of rotavirus caused diarrhea among infants and its magnitude as a cause of the most common clinical attending symptoms to the daily care clinics and hospital admission.. The aim of this study was to estimate the prevalence of rotavirus caused gastroenteritis and identify the clinical factors associated with rotavirus caused diarrhea among infants admitted to the hospital or treated as outpatien
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17

Sdiri-Loulizi, Khira, Katia Ambert-Balay, Hakima Gharbi-Khelifi, et al. "Molecular epidemiology and clinical characterization of group A rotavirus infections in Tunisian children with acute gastroenteritis." Canadian Journal of Microbiology 57, no. 10 (2011): 810–19. http://dx.doi.org/10.1139/w11-074.

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Rotaviruses are the most common cause of severe viral gastroenteritis in early childhood worldwide. Thus, the objectives of our study were to determine the molecular epidemiology and the clinical features of rotavirus gastroenteritis in Tunisia. Between January 2003 and April 2007, a prospective study was conducted on 788 stool samples collected from children under 12 years of age who were suffering from acute gastroenteritis. Rotavirus was detected by multiplex RT-PCR in 27% (n = 213) of samples, among them 79.3% (n = 169) cases were monoinfections. The frequency of rotavirus infections was s
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18

Christensen, M. L. "Human viral gastroenteritis." Clinical Microbiology Reviews 2, no. 1 (1989): 51–89. http://dx.doi.org/10.1128/cmr.2.1.51.

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During the last 15 years, several different groups of fastidious viruses that are responsible for a large proportion of acute viral gastroenteritis cases have been discovered by the electron microscopic examination of stool specimens. This disease is one of the most prevalent and serious clinical syndromes seen around the world, especially in children. Rotaviruses, in the family Reoviridae, and fastidious fecal adenoviruses account for much of the viral gastroenteritis in infants and young children, whereas the small caliciviruses and unclassified astroviruses, and possibly enteric coronavirus
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19

Baker, Julia M., Jacqueline E. Tate, Juan Leon, Michael J. Haber, Virginia E. Pitzer, and Benjamin A. Lopman. "Postvaccination Serum Antirotavirus Immunoglobulin A as a Correlate of Protection Against Rotavirus Gastroenteritis Across Settings." Journal of Infectious Diseases 222, no. 2 (2020): 309–18. http://dx.doi.org/10.1093/infdis/jiaa068.

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Abstract Background A correlate of protection for rotavirus gastroenteritis would facilitate rapid assessment of vaccination strategies and the next generation of rotavirus vaccines. We aimed to quantify a threshold of postvaccine serum antirotavirus immunoglobulin A (IgA) as an individual-level immune correlate of protection against rotavirus gastroenteritis. Methods Individual-level data on 5074 infants in 9 GlaxoSmithKline Rotarix Phase 2/3 clinical trials from 16 countries were pooled. Cox proportional hazard models were fit to estimate hazard ratios (HRs) describing the relationship betwe
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Dukhovlinov, I. V., E. G. Bogomolova, E. A. Fedorova, and A. S. Simbirtsev. "Immunogenic Properties Studyoffusion Recombinant Proteins Based on VP6 and VP8 of Human Rotavirus A." Epidemiology and Vaccine Prevention 14, no. 2 (2015): 96–101. http://dx.doi.org/10.31631/2073-3046-2015-14-2-96-101.

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Rotavirus infection is the leading cause of severe acute diarrhea among young children worldwide. Contagion with these viruses often leads to severe dehydration of organism. Rotaviral gastroenteritis cases may repeat intra vitam. Because of the absence of drugs with direct action on rotavirus, a timely vaccination is considered the most effective way of this disease's control. Nowadays vaccines based on attenuated alive rotaviral strains are used for this purpose, which can result in different complications. In this work the immunogenicity of recombinant fusion proteins VP6VP8 and FliCVP6VP8 -
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21

Saeed, Ali Y. "Acute Rotavirus gastroenteritis among children." Journal of Zankoy Sulaimani - Part A 3, no. 1 (2000): 73–78. http://dx.doi.org/10.17656/jzs.10054.

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22

Dr., Komal Nizam Dr Muhammad Usman Khan Dr Qurrat ul Aen Zafar. "A RESRARCH STUDY TO ASSESS THE CLINICAL COMPLICATIONS AND FEATURES OF ROTAVIRUS GASTROENTERITIS AMONG CHILDREN." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES o6, no. 05 (2019): 9377–83. https://doi.org/10.5281/zenodo.2717919.

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<strong><em>Background: </em></strong><em>Rotavirus is one of the major viruses causing an onset of acute gastroenteritis among children and it is also correlated with neurological complications such as encephalopathy and seizures.</em> <strong><em>Objective: </em></strong><em>This research aims to investigate the complications and presentation of rotavirus versus non-rotavirus gastroenteritis.</em> <strong><em>Methods: </em></strong><em>This retrospective, hospital-based and case-control study was carried out at Jinnah Hospital, Lahore (October 2017 to August 2018). The research included chil
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Doutchi, Mahamadou, Salifou Ibrahim Alkassoum, Inkov Ivan, Harouna Amadou, Issaka Modi, and Kayryakova Mila. "Gastro entérites à rota virus chez les enfants de 0 à 59 mois à l'hôpital national de Niamey." International Journal of Medical Reviews and Case Reports 3, no. 9 (2019): 558–64. https://doi.org/10.5455/IJMRCR.rotavirus-gastroenteritis.

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Introduction: The gastroenteritis is an inflation of lining and stomach. The genre rotavirus of Reovirus of the family of rotaviridae constitutes the first cause of viral acute gastroenteritis in children from 3 months to 2 years old. The aim of the study was to evaluate the epidemiological monitoring of acute gastroenteritis of rotavirus to the children under 5 years in HNN. Methodology: It is a prospective and descriptive study of 8 months from February to September 2016, which concerned 84 patients. The tool of collect is composed of inquiry form, laboratory register and exam bulletin. Resu
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Jung, Jinseok, Jaehoon Bae, Ji Sun Park, Seung Woong Lee, Jae-Ho Jeong, and Su-Jin Park. "In Vitro Anti-Rotaviral Activity of Bavachin Isolated from Psoralea corylifolia L. (Fabaceae)." Veterinary Sciences 11, no. 5 (2024): 188. http://dx.doi.org/10.3390/vetsci11050188.

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Rotavirus is the main causative agent of viral gastroenteritis among young animals worldwide. Currently, no clinically approved or effective antiviral drugs are available to combat rotavirus infections. Herein, we evaluated the anti-rotaviral activities of extracts and bavachin isolated from Psoralea corylifolia L. (Fabaceae) (P. corylifolia) against the bovine rotavirus G8P[7] and porcine rotavirus G5P[7] in vitro. Two assay strategies were performed: (1) a virucidal assay to reduce viral infectivity by virus neutralization and (2) a post-treatment assay to assess viral replication suppressio
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O, Kılıçaslan, Sav NM, Karaca S, Şahin IE, Öksüz S, and Kocabay K. "Role of routine laboratory markers in the diagnosis of rotavirus and adenovirus gastroenteritis." Journal of Medical and Scientific Research 10, no. 2 (2022): 76–81. http://dx.doi.org/10.17727/jmsr.2022/10-15.

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Purpose: The present study aimed to evaluate and estimate the additional and auxiliary diagnostic value of routine laboratory parameters in patients with acute diarrhea caused by rotavirus and adenovirus. Methods/ patients: A total of 6784 patients diagnosed with acute gastroenteritis were evaluated. Rotavirus and adenovirus infection was diagnosed via a Qualitative immunochromatographic combo rapid cassette antigen test. Complete blood count and biochemical blood tests were performed in all the patients and were compared between the groups according to the positivity or negativity of the viru
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Sinnott, John T., and Margarita R. Cancio. "Rotavirus." Infection Control 8, no. 12 (1987): 519–21. http://dx.doi.org/10.1017/s0195941700067606.

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Acute gastroenteritis is a public health problem of global proportions. Worldwide there are more than 700 million cases of diarrheal disease resulting in around 5 million deaths. In the United States the incidence of acute gastroenteritis is 11% each year and it is second only to respiratory infection as a contagious disease in the American family. The etiology of this common syndrome is obscure but it is becoming apparent that much of this disease is viral in origin. Recent research has elucidated a growing number of human pathogens: Norwalk-like agents, adenoviruses, caliciviruses, and astro
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CHANDOLA, T. R., S. TANEJA, N. GOYAL, et al. "Descriptive epidemiology of rotavirus infection in a community in North India." Epidemiology and Infection 141, no. 10 (2013): 2094–100. http://dx.doi.org/10.1017/s0950268812002762.

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SUMMARYIn India, rotavirus infections cause the death of 98621 children each year. In urban neighbourhoods in Delhi, children were followed up for 1 year to estimate the incidence of rotavirus gastroenteritis and common genotypes. Infants aged ⩽1 week were enrolled in cohort 1 and infants aged 12 months (up to +14 days) in cohort 2. Fourteen percent (30/210) gastroenteritis episodes were positive for rotavirus. Incidence rates of rotavirus gastroenteritis episodes in the first and second year were 0·18 [95% confidence interval (CI) 0·10–0·27] and 0·14 (95% CI 0·07–0·21) episodes/child-year, re
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Wang, Yunjin, Li Yu, and Xu Zhou. "Research progress in detection of rotavirus." Journal of Applied Virology 2, no. 4 (2013): 25. http://dx.doi.org/10.21092/jav.v2i4.16.

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&lt;p&gt;RVs causes significant morbidity and mortality world widely, they are the main etiologic agents of serious diarrheal disease and the major cause of gastroenteritis in infants and young children under 5 year of age. Because there is no specific treatment for RV infections, rotavirus vaccines were considered to be the most effective way to prevent rotavirus infections. Thus, a rapid, specific and sensitive detection method is of the utmost importance for diagnosing and monitoring of rotaviruses, and also for evaluating of rotavirus vaccines. In this report, we reviewed the process of the
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LORGELLY, P. K., D. JOSHI, M. ITURRIZA GÓMARA, et al. "Infantile gastroenteritis in the community:a cost-of-illness study." Epidemiology and Infection 136, no. 1 (2007): 34–43. http://dx.doi.org/10.1017/s0950268807008163.

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SUMMARYRotavirus infections are the main cause of gastroenteritis in infants and children and it is expected that by the age of 5 years, nearly every child will have experienced at least one episode of rotavirus gastroenteritis. While severe cases are hospitalized, milder disease is either treated at home or by the GP, and as such the true prevalence of rotavirus infection in the community, and the burden of disease, is unknown. This paper reports the results of a cost-of-illness study which was conducted alongside a structured community surveillance study. Forty-eight percent of our sample wa
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Hjelt, Karsten, Per C. Grauballe, Lene Andersen, Peter O. Schiøtz, Peter Howitz, and Peter A. Krasilnikoff. "Antibody Response in Serum and Intestine in Children up to Six Months After a Naturally Acquired Rotavirus Gastroenteritis." Journal of Pediatric Gastroenterology and Nutrition 5, no. 1 (1986): 74–80. http://dx.doi.org/10.1002/j.1536-4801.1986.tb09019.x.

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SummaryThe aim of this study was to provide detailed information about the local and systemic antibody response and their relationship following a rotavirus gastroenteritis. Rotavirus‐specific immunoglobulins were analyzed by enzyme‐linked immunosorbent assay (ELISA). The study included 49 children referred to hospital with rotavirus gastroenteritis and 16 children with nonrotavirus gastroenteritis. The concentrations of rotavirus immunoglobulin A (IgA) in serum increased within the first 2 weeks and those of rotavirus IgG within the first month after the onset of diarrhea. Thereafter, they re
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Bondarev, V. P., V. A. Shevtsov, I. N. Indikova, E. E. Evreinova, and D. V. Gorenkov. "Rotavirus Epidemiology and Vaccination Tactics." BIOpreparations. Prevention, Diagnosis, Treatment 19, no. 2 (2019): 81–87. http://dx.doi.org/10.30895/2221-996x-2019-19-2-81-87.

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Rotavirus infection is a widespread cause of severe gastroenteritis in children in low-income countries. Specific prophylaxis in young children has become the most important means of combating severe rotavirus gastroenteritis. The review presents current data on the molecular biology and genetic diversity of rotaviruses, interaction of viral proteins with host cell receptors, molecular aspects of infectivity and pathogenesis of rotavirus infection, and the development of immunity. It addresses a new approach to the epidemiology of rotavirus infection which regards it as a manageable infection,
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CILLA, G., M. MONTES, M. GOMARIZ, et al. "Rotavirus genotypes in children in the Basque Country (North of Spain): rapid and intense emergence of the G12[P8] genotype." Epidemiology and Infection 141, no. 4 (2012): 868–74. http://dx.doi.org/10.1017/s0950268812001306.

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SUMMARYBetween July 2009 and June 2011, rotavirus was detected in 507 of 4597 episodes of acute gastroenteritis in children aged &lt;3 years in Gipuzkoa (Basque Country, Spain), of which the G-type was determined in 458 (90·3%). During the annual seasonal epidemic of 2010–2011, the unusual G-type 12 was predominant, causing 65% (145/223) of cases of rotavirus gastroenteritis. All the G12 strains were clustered in lineage III and were preferentially associated with P-type 8. This epidemic was characterized by broad geographical distribution (rural and urban) and, over 7 months, affected both in
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Abood, W. S. "The molecular epidemiology of rotavirus strains causing gastroenteritis in infant in the region of Mid Iraq." Al-Qadisiyah Journal of Veterinary Medicine Sciences 12, no. 1 (2013): 121. http://dx.doi.org/10.29079/vol12iss1art240.

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Rotavirus diarrhea is a leading cause of child death. It is a major concern in developing and developed countries. In Iraq, few studies and analysis were executed for genetic assessment of rotavirus.The aim of this study was to estimate the prevalence of rotavirus caused gastroenteritis and identify the distribution of the circulating G and P types of rotavirus among infants admitted to the hospital or treated as outpatients in three governorates in the region of Mid-Iraq for symptoms of gastroenteritis.This study was undertaken during the period from June 2010 to April 2012 in infants under 1
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Mojahed, Nooshin, Mohammad Ali Mohammadkhani, Masoumeh Pourasgari, Golnosh Gol-Jah Rad, and Ashraf Mohamadkhani. "Viral Gastroenteritis Prevalence in Iranian Pediatric Population: A Systematic Review." Avicenna Journal of Clinical Microbiology and Infection 9, no. 3 (2022): 124–29. http://dx.doi.org/10.34172/ajcmi.2022.3389.

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Background: Viral gastroenteritis infection, a prevalent condition in adolescents and children, is still a rigid and serious problem among humans. This disease is responsible for up to three million fatalities nationwide. noroviruses, rotaviruses, astroviruses, adenoviruses, and sapoviruses are the most common and well-known pathogens associated with viral gastroenteritis agents. In this systematic review, we extracted all original articles and data on viral gastroenteritis that were performed on the Iranian pediatric population. Methods: To investigate the viral agent pathogens of gastroenter
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Федулова, T. Fedulova, Сапожников, Vladimir Sapozhnikov, Дёмина, and S. Demina. "The clinical manifestations of rotavirus infection in children." Journal of New Medical Technologies. eJournal 8, no. 1 (2014): 0. http://dx.doi.org/10.12737/7232.

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Currently, there is prevalence of rotavirus infection among children, mass outbreaks of infections which are independent on the sanitary-hygienic conditions, there is no rational approach to the treatment of this disease. However, the clinical manifestations of this disease are vary depending on the age and are associated to available conditionally pathogenic flora. The study revealed that the most pronounced are the symptoms of gastro-duodenal lesions in children with acute rotavirus gastroenteritis at the initial stage of the disease. Flatu-lence, bloating, phenomena hematolite didn’t observ
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Patton, John T., and Ulrich Desselberger. "Rotaviruses and Rotavirus Vaccines: Special Issue Editorial." Viruses 16, no. 11 (2024): 1665. http://dx.doi.org/10.3390/v16111665.

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Snyder, Anthony J., Chantal A. Agbemabiese, and John T. Patton. "Production of OSU G5P[7] Porcine Rotavirus Expressing a Fluorescent Reporter via Reverse Genetics." Viruses 16, no. 3 (2024): 411. http://dx.doi.org/10.3390/v16030411.

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Rotaviruses are a significant cause of severe, potentially life-threatening gastroenteritis in infants and the young of many economically important animals. Although vaccines against porcine rotavirus exist, both live oral and inactivated, their effectiveness in preventing gastroenteritis is less than ideal. Thus, there is a need for the development of new generations of porcine rotavirus vaccines. The Ohio State University (OSU) rotavirus strain represents a Rotavirus A species with a G5P[7] genotype, the genotype most frequently associated with rotavirus disease in piglets. Using complete ge
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Arun, Ponnambalam, Vidya Padmanabhan, and K. Kaveri. "Serologic and molecular characterization of rotavirus from children with acute gastroenteritis in Chennai, Tamil Nadu, India." International Journal of Contemporary Pediatrics 7, no. 8 (2020): 1734. http://dx.doi.org/10.18203/2349-3291.ijcp20203167.

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Background: Rotavirus gastroenteritis is the leading cause of diarrhea in infants and young children worldwide. Although, Rotavirus vaccine has been introduced in 2017 in states like Tamil Nadu, there are reports of the role of Rotavirus as one of high disease burden agents with genetic variants arising, especially from low-income countries like India.Methods: Authors evaluated stool samples from 507 children with acute gastroenteritis Rotavirus A among the hospitalized children (&gt;5 years) to provide baseline information on changing profile in this state. The stool samples were collected an
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Elottol, Abed El Kader, Akram Altaher, Basma Alnajjar, Felastin AbSitta, Asala Abu Adwan, and Aya Dheer. "Rotavirus Gastroenteritis among Children Under five years of agein Gaza, Palestine." Israa University Journal for Applied Science 3 (October 1, 2019): 102–15. http://dx.doi.org/10.52865/csrz6539.

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Rotavirus belongs to the Reoviridae family, a group of segmented double stranded Ribonucleic acid viruses. The virus is a major cause of gastroenteritis and diarrhea in infants and young children worldwide. Rotaviral gastroenteritis may result in mortality for populations at risk such as infants, the elderly and immune compromised patients. Objective: This study aims to evaluate occurrence of rotavirus among under five years children with acute gastroenteritis attending Nasser complex and European Gaza Governmental Hospitals, Palestine during august 2018. Methods: Cross sectional design used i
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Şenol, Feray Ferda, İlkay Bahçeci, Altay Babacan, Yunus Emre İbik, and Ferhan Korkmaz. "Prevalence of Rotavirus and Adenovirus in a City Hospital in the Eastern Anatolia Region of Türkiye." Journal of Molecular Virology and Immunology 3, no. 2 (2022): 98–104. https://doi.org/10.46683/jmvi.2022.53.

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<strong>Abstract</strong> In this study, it was aimed to evaluate the seasonal distribution of rotavirus and enteric adenovirus prevalence and demographic data of patients of all age groups who applied to our hospital with the complaint of acute gastroenteritis. A total of 12,840 patients aged 0-90 years, who applied to our hospital (Elazığ&nbsp;Fethi Sekin City Hospital) with the complaint of acute gastroenteritis between 15 August 2018 and 18 October 2021, were retrospectively analyzed. The presence of rotavirus and adenovirus antigens was determined from stool samples by qualitative immunoc
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Mandolo, Jonathan J., Marc Y. R. Henrion, Chimwemwe Mhango, et al. "Reduction in Severity of All-Cause Gastroenteritis Requiring Hospitalisation in Children Vaccinated against Rotavirus in Malawi." Viruses 13, no. 12 (2021): 2491. http://dx.doi.org/10.3390/v13122491.

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Rotavirus is the major cause of severe gastroenteritis in children aged &lt;5 years. Introduction of the G1P[8] Rotarix® rotavirus vaccine in Malawi in 2012 has reduced rotavirus-associated hospitalisations and diarrhoeal mortality. However, the impact of rotavirus vaccine on the severity of gastroenteritis presented in children requiring hospitalisation remains unknown. We conducted a hospital-based surveillance study to assess the impact of Rotarix® vaccination on the severity of gastroenteritis presented by Malawian children. Stool samples were collected from children aged &lt;5 years who r
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SERT, Sadiye, and Berna ERAYMAN. "Frequency and seasonal distribution of adenovirus and rotavirus in children diagnosed with acute gastroenteritis: A single centre experience." Journal of Contemporary Medicine 13, no. 2 (2023): 353–59. http://dx.doi.org/10.16899/jcm.1259028.

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Aim: We aimed to investigate the relationship between age, gender, and season with respect to the frequency of rotavirus and adenovirus antigens in stool specimens obtained from children one month to 18 years of age who were diagnosed with acute gastroenteritis.&#x0D; Materials and Methods: The records of stool specimen analyses for 1960 patients with diagnosis of acute gastroenteritis at our hospital from January 2017 to August 2022 were retrospectively examined. The patient's admission year, season, gender, age, and stool viral antigen test results were retrospectively analyzed from the file
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Damtie, Debasu, Mulugeta Melku, Belay Tessema, and Anastasia N. Vlasova. "Prevalence and Genetic Diversity of Rotaviruses among under-Five Children in Ethiopia: A Systematic Review and Meta-Analysis." Viruses 12, no. 1 (2020): 62. http://dx.doi.org/10.3390/v12010062.

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Rotavirus infection is the major cause of acute gastroenteritis among children globally. Sub-Saharan Africa including Ethiopia is disproportionally affected by the disease. The aims of this review were to determine the pooled prevalence of rotavirus infection among children under-five and to identify the dominant rotavirus genotypes in Ethiopia. Twelve studies were included to estimate the pooled prevalence of rotavirus acute gastroenteritis and five studies were used to determine predominantly circulating genotypes of rotavirus. The pooled prevalence of rotavirus infection was 23% (95% CI = 2
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Bennett, A., N. Bar-Zeev, K. C. Jere, et al. "Determination of a Viral Load Threshold To Distinguish Symptomatic versus Asymptomatic Rotavirus Infection in a High-Disease-Burden African Population." Journal of Clinical Microbiology 53, no. 6 (2015): 1951–54. http://dx.doi.org/10.1128/jcm.00875-15.

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We evaluated quantitative real-time PCR to establish the diagnosis of rotavirus gastroenteritis in a high-disease-burden population in Malawi using enzyme immunoassay as the gold standard diagnostic test. In 146 children with acute gastroenteritis and 65 asymptomatic children, we defined a cutoff point in the threshold cycle value (26.7) that predicts rotavirus-attributable gastroenteritis in this population. These data will inform the evaluation of direct and indirect rotavirus vaccine effects in Africa.
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Güzel, Mustafa, Orhan Akpınar, and Muhammet Burak Kılıç. "Prevalence of Rotavirus-Associated Acute Gastroenteritis Cases in Early Childhood in Turkey: Meta-Analysis." Children 7, no. 10 (2020): 159. http://dx.doi.org/10.3390/children7100159.

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Background: Rotavirus is globally the most common viral pathogen in childhood gastroenteritis. This study aimed to estimate the number of Turkish children suffering from early-childhood gastroenteritis by rotavirus by performing a meta-analysis. Methods: Meta-analysis following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines was performed. Following the guidelines, primary studies were found reporting the prevalence of rotavirus gastroenteritis in Turkey. We performed a computerized search of published studies in national and international databases f
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Alqurayn, Ahmed K., Obeid E. Obeid, and Khaled R. Alkharsah. "Rotavirus and adenovirus in children evaluated for viral gastroenteritis at a single healthcare center in the Eastern Province of Saudi Arabia: A perspective of two decades." Journal of Family and Community Medicine 31, no. 2 (2024): 133–39. http://dx.doi.org/10.4103/jfcm.jfcm_273_23.

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BACKGROUND: The aim of this study was to determine the distribution of rotavirus and adenovirus in pediatric patients evaluated for viral gastroenteritis in a hospital in the Eastern Province of Saudi Arabia for 22 years. MATERIALS AND METHODS: This was a retrospective study based in a secondary healthcare center in Saudi Arabia. Laboratory and demographic data were collected from hospital records for all pediatric patients (up to 14 years old) evaluated for viral gastroenteritis by rotavirus/adenovirus antigen detection kit from January 2000 to December 2022. Data were analyzed utilizing SPSS
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Cheung, Winsome, Michael Gill, Alessandro Esposito, et al. "Rotaviruses Associate with Cellular Lipid Droplet Components To Replicate in Viroplasms, and Compounds Disrupting or Blocking Lipid Droplets Inhibit Viroplasm Formation and Viral Replication." Journal of Virology 84, no. 13 (2010): 6782–98. http://dx.doi.org/10.1128/jvi.01757-09.

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ABSTRACT Rotaviruses are a major cause of acute gastroenteritis in children worldwide. Early stages of rotavirus assembly in infected cells occur in viroplasms. Confocal microscopy demonstrated that viroplasms associate with lipids and proteins (perilipin A, ADRP) characteristic of lipid droplets (LDs). LD-associated proteins were also found to colocalize with viroplasms containing a rotaviral NSP5-enhanced green fluorescent protein (EGFP) fusion protein and with viroplasm-like structures in uninfected cells coexpressing viral NSP2 and NSP5. Close spatial proximity of NSP5-EGFP and cellular pe
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BADAWY, AMIN S., CHARLES P. GERBA, and LEE M. KELLEY. "Development of a Method for Recovery of Rotavirus from the Surface of Vegetables." Journal of Food Protection 48, no. 3 (1985): 261–64. http://dx.doi.org/10.4315/0362-028x-48.3.261.

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Rotaviruses cause waterborne disease outbreaks of gastroenteritis from sewage contaminated water, but methods have not been available to assess the potential for transmission of rotavirus by uncooked foods. A method was developed for recovery of rotavirus from the surface of vegetables. The simian rotavirus SA-11, used as a model for the human rotavirus, was adsorbed onto lettuce and the effects of various eluents tested for its recovery. The maximum recovery of rotavirus occurred with a solution of 3% beef extract at pH 8.0 after 5 min of exposure. Longer exposure times did not enhance virus
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Yuzhakov, Anton, Ksenia Yuzhakova, Nadezhda Kulikova, et al. "Prevalence and Genetic Diversity of Group A Rotavirus Genotypes in Moscow (2019–2020)." Pathogens 10, no. 6 (2021): 674. http://dx.doi.org/10.3390/pathogens10060674.

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Group A rotavirus (RVA) infection is the leading cause of hospitalization of children under 5 years old, presenting with symptoms of acute gastroenteritis. The aim of our study was to explore the genetic diversity of RVA among patients admitted to Moscow Infectious Disease Clinical Hospital No. 1 with symptoms of acute gastroenteritis. A total of 653 samples were collected from May 2019 through March 2020. Out of them, 135 (20.67%) fecal samples were found to be positive for rotavirus antigen by ELISA. RT-PCR detected rotavirus RNA in 80 samples. Seven G-genotypes (G1, G2, G3, G4, G8, G9, and
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Deliu, Ionica, and Sînziana Cosmina Georgescu. "THE INCIDENCE OF ADENOVIRUS AND ROTAVIRUS IN PEDIATRIC PATIENTS WITH GASTROENTERITIS." CURRENT TRENDS IN NATURAL SCIENCES 12, no. 23 (2023): 54–58. http://dx.doi.org/10.47068/ctns.2023.v12i23.007.

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Symptomatic or asymptomatic pediatric diarrhea is a worldwide public health problem, one of the important causes of morbidity and mortality in children 5 years and below. The main causes of viral acute gastroenteritis in the childhood are adenoviruses, rotaviruses, astroviruses and caliciviruses, especially between six months and two years of age. The aim of this paper was to establish the incidence of gastroenteritis with adenovirus and rotavirus in pediatric patients in Curtea de Arges (Arges) in 17 months (between January 1st, 2021 and June 1st, 2022). The immunochromatographic assay was us
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