Academic literature on the topic 'Scas02'

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Journal articles on the topic "Scas02"

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Tan, Jun-Kai, Guo Liu, Long-Xiang Huang, et al. "Evaluation of trabecular meshwork-specific promoters in vitro and in vivo using scAAV2 vectors expressing C3 transferase." International Journal of Ophthalmology 16, no. 8 (2023): 1196–209. http://dx.doi.org/10.18240/ijo.2023.08.03.

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AIM: To evaluate the potential of two trabecular meshwork (TM)-specific promoters, Chitinase 3-like 1 (Ch3L1) and matrix gla protein (MGP), for improving specificity and safety in glaucoma gene therapy based on self-complementary AAV2 (scAAV2) vector technologies. METHODS: An scAAV2 vector with C3 transferase (C3) as the reporter gene (scAAV2-C3) was selected. The scAAV2-C3 vectors were driven by Ch3L1 (scAAV2-Ch3L1-C3), MGP (scAAV2-MGP-C3), enhanced MGP (scAAV2-eMGP-C3) and cytomegalovirus (scAAV2-CMV-C3), respectively. The cultured primary human TM cells were treated with each vector at diff
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Nishimura, Yorihiro, Kei Sato, Yoshio Koyanagi, et al. "Enterovirus A71 does not meet the uncoating receptor SCARB2 at the cell surface." PLOS Pathogens 20, no. 2 (2024): e1012022. http://dx.doi.org/10.1371/journal.ppat.1012022.

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Enterovirus A71 (EV-A71) infection involves a variety of receptors. Among them, two transmembrane protein receptors have been investigated in detail and shown to be critical for infection: P-selectin glycoprotein ligand-1 (PSGL-1) in lymphocytes (Jurkat cells), and scavenger receptor class B member 2 (SCARB2) in rhabdomyosarcoma (RD) cells. PSGL-1 and SCARB2 have been reported to be expressed on the surface of Jurkat and RD cells, respectively. In the work reported here, we investigated the roles of PSGL-1 and SCARB2 in the process of EV-A71 entry. We first examined the expression of SCARB2 in
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Liu, Lixia, Zhenheng Guo, Quyen Tieu, Anna Castle, and David Castle. "Role of Secretory Carrier Membrane Protein SCAMP2 in Granule Exocytosis." Molecular Biology of the Cell 13, no. 12 (2002): 4266–78. http://dx.doi.org/10.1091/mbc.e02-03-0136.

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In secretory carrier membrane proteins (SCAMPs), the most conserved structural segment is between transmembrane spans 2 and 3, facing the cytosol. A synthetic peptide, CWYRPIYKAFR (E peptide), from this segment of SCAMP2 potently inhibits exocytosis in permeabilized neuroendocrine (PC12) cells. E peptide blocked discharge of35S-labeled secretogranin with the same structural selectivity and potency as observed for hexosaminidase secretion in mast cells. SCAMPs 1 and 2 are concentrated primarily on intracellular membranes in PC12 cells. Both, however, are found on plasma membranes, but neither i
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Liu, Lixia, Haini Liao, Anna Castle, et al. "SCAMP2 Interacts with Arf6 and Phospholipase D1 and Links Their Function to Exocytotic Fusion Pore Formation in PC12 Cells." Molecular Biology of the Cell 16, no. 10 (2005): 4463–72. http://dx.doi.org/10.1091/mbc.e05-03-0231.

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SNAP receptor (SNARE)-mediated fusion is regarded as a core event in exocytosis. Exocytosis is supported by other proteins that set up SNARE interactions between secretory vesicle and plasma membranes or facilitate fusion pore formation. Secretory carrier membrane proteins (SCAMPs) are candidate proteins for functioning in these events. In neuroendocrine PC12 cells, SCAMP2 colocalizes on the cell surface with three other proteins required for dense-core vesicle exocytosis: phospholipase D1 (PLD1), the small GTPase Arf6, and Arf6 guanine nucleotide exchange protein ARNO. Arf6 and PLD1 coimmunop
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Sheta, Mona, Kunihiro Yoshida, Hideka Kanemoto, Stuart K. Calderwood, and Takanori Eguchi. "Stress-Inducible SCAND Factors Suppress the Stress Response and Are Biomarkers for Enhanced Prognosis in Cancers." International Journal of Molecular Sciences 24, no. 6 (2023): 5168. http://dx.doi.org/10.3390/ijms24065168.

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The cell stress response is an essential system present in every cell for responding and adapting to environmental stimulations. A major program for stress response is the heat shock factor (HSF)–heat shock protein (HSP) system that maintains proteostasis in cells and promotes cancer progression. However, less is known about how the cell stress response is regulated by alternative transcription factors. Here, we show that the SCAN domain (SCAND)-containing transcription factors (SCAN-TFs) are involved in repressing the stress response in cancer. SCAND1 and SCAND2 are SCAND-only proteins that c
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Zonta, Marise Bueno, Hélio A. G. Teive, Carlos Henrique F. Camargo, et al. "Comparing loss of balance and functional capacity among patients with SCA2, SCA3 and SCA10." Clinical Neurology and Neurosurgery 214 (March 2022): 107150. http://dx.doi.org/10.1016/j.clineuro.2022.107150.

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Quraishi, Imran H., Anna M. Szekely, Anushree C. Shirali, Pramod K. Mistry, and Lawrence J. Hirsch. "Miglustat Therapy for SCARB2-Associated Action Myoclonus–Renal Failure Syndrome." Neurology Genetics 7, no. 5 (2021): e614. http://dx.doi.org/10.1212/nxg.0000000000000614.

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ObjectiveWe evaluated whether substrate reduction therapy with miglustat could alter the course of action myoclonus–renal failure syndrome (AMRF), a rare, progressive myoclonic epilepsy with early mortality caused by scavenger receptor class B member 2 (SCARB2) gene mutations.MethodsWe identified an AMRF patient with a biallelic combination of SCARB2 mutations determined by whole exome sequencing. SCARB2 encodes a protein that traffics β-glucocerebrosidase to the lysosomal membrane. Mutations lead to a complex pattern of glucosylceramide accumulation and neurologic symptoms including progressi
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Ishihara, Akikazu, Jeffrey S. Bartlett, and Alicia L. Bertone. "Inflammation and Immune Response of Intra-Articular Serotype 2 Adeno-Associated Virus or Adenovirus Vectors in a Large Animal Model." Arthritis 2012 (January 11, 2012): 1–8. http://dx.doi.org/10.1155/2012/735472.

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Intra-articular gene therapy has potential for the treatment of osteoarthritis and rheumatoid arthritis. To quantify in vitro relative gene transduction, equine chondrocytes and synovial cells were treated with adenovirus vectors (Ad), serotype 2 adeno-associated virus vectors (rAAV2), or self-complementary (sc) AAV2 vectors carrying green fluorescent protein (GFP). Using 6 horses, bilateral metacarpophalangeal joints were injected with Ad, rAAV2, or scAAV2 vectors carrying GFP genes to assess the in vivo joint inflammation and neutralizing antibody (NAb) titer in serum and joint fluid. In vit
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Kitamoto, Takuya, and Aya Kitamoto. "Integrative proteomic and lipidomic analysis of GNB1 and SCARB2 knockdown in human subcutaneous adipocytes." PLOS ONE 20, no. 3 (2025): e0319163. https://doi.org/10.1371/journal.pone.0319163.

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Obesity, a global public health concern, is influenced by various factors, including genetic predispositions. Although many obesity-associated genes have been identified through genome-wide association studies (GWAS), the molecular mechanisms linking these genes to adipose tissue function remain largely unexplored. This study integrates proteomic data on adipocyte fat accumulation with GWAS data on obesity to unravel the roles of the identified key candidate genes — G protein subunit beta 1 (GNB1) and scavenger receptor class B member 2 (SCARB2) — involved in fat accumulation. We utilized RNA
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Wu, T. T., and J. D. Castle. "Evidence for colocalization and interaction between 37 and 39 kDa isoforms of secretory carrier membrane proteins (SCAMPs)." Journal of Cell Science 110, no. 13 (1997): 1533–41. http://dx.doi.org/10.1242/jcs.110.13.1533.

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Secretory carrier membrane proteins (SCAMPs) are proteins of post-Golgi recycling carriers, including regulated secretory organelles. The two major size variants, SCAMP1 (37 kDa) and SCAMP2 (39 kDa), extensively colocalize in membranes of fibroblasts and parotid acinar cells based on immunocytochemistry and velocity centrifugation, although the relative amounts of each variant may differ in selected organelles. SCAMP1, and to a lesser extent, SCAMP2, are substrates for chemical crosslinking in situ, and the recognizable crosslinking products of SCAMP1 suggest potential formation of homomultime
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Dissertations / Theses on the topic "Scas02"

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Peters, Judith [Verfasser]. "Identifizierung und Charakterisierung neuer Interaktionspartner des lysosomalen integralen Membranproteins Typ-2 (LIMP-2/SCARB2) / Judith Peters." Kiel : Universitätsbibliothek Kiel, 2018. http://d-nb.info/1153768445/34.

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Wesseler, Sophia Charlotte [Verfasser]. "Charakterisierung des Promotors des Gens für das Lysosomale Integrale Membranprotein Typ-2 (LIMP-2/SCARB2) / Sophia Charlotte Wesseler." Kiel : Universitätsbibliothek Kiel, 2017. http://d-nb.info/1142154742/34.

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Bampi, Giovana Bavia. "Estudo de haplótipos em famílias com ataxia espinocerebelar tipo 10(SCA10) : evidências de um efeito fundador da mutação." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2015. http://hdl.handle.net/10183/119618.

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A ataxia espinocerebelar tipo 10 (SCA10) é uma doença neurodegenerativa rara de herança autossômica dominante caracterizada por atrofia cerebelar com alterações da marcha e, em alguns casos, convulsões. A SCA10 é causada por expansões de repetições pentanucleotídicas ATTCT no íntron 9 do gene ATXN10, o qual se localiza no locus 22q13. Alelos normais apresentam entre 10 a 29 repetições e o alelo patogênico apresenta entre 800 a 4.500 repetições. Até o momento, casos de SCA10 foram descritos apenas em pacientes miscigenados de países do continente americano como México, Brasil, Argentina, Venezu
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Öhlund, Rebecca. "Könsskillnader i välbefinnande utifrån val av fysisk aktivitet." Thesis, Örebro universitet, Institutionen för juridik, psykologi och socialt arbete, 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-43343.

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Samhället uppmuntrar individer att se över sina hälsovanor för att öka välbefinnandet. Syftet var att undersöka om val av fysisk aktivitet hade effekt på den generella hälsan i ökat subjektivt välbefinnande samt om det fanns könsskillnader i dessa. Sextio män och kvinnor mellan 25-50 år valdes slumpmässigt ut från träningsanläggningar för att besvara the 12-item General Health Questionnaire (GHQ-12) samt Swedish Core Affect Scale (SCAS). Resultatet visade på signifikant ökning av välbefinnande efter fysisk aktivitet samt inga könsskillnader. Dock fanns en signifikant interaktionseffekt mellan
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Satterfield, Terrence Forrest. "Genetic and biochemical analysis of the Drosophila melanogaster homolog of the human SCA2 gene /." Thesis, Connect to this title online; UW restricted, 2005. http://hdl.handle.net/1773/10245.

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Patterson, Erika K. "The social class attitudes scale (SCAS) : instrument development and estimates for reliability and validity /." free to MU campus, to others for purchase, 2003. http://wwwlib.umi.com/cr/mo/fullcit?p3099621.

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Ngwamidiba, Maxime. "Etude moléculaire des gènes SCA1 et SCA2 codant des protéines autotransporteurs chez les membres du genre " rickettsia"." Aix-Marseille 2, 2006. http://www.theses.fr/2006AIX20660.

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Des analyses d'ADN sur les restes des soldats de la Grande Armée de Napoléon (1812) ont révélé la présence entre autre de Rickettsia prowazekii. Pourtant la rickettsiologie ne commençera qu'avec les travaux de Ricketts et von Prowazek en 1910, et ne cessera de s'alimenter d'espèces et de pathologies nouvelles. En tant que premières bactéries intracellulaires strictes décrites, la taxonomie des rickettsies rassemblait initialement sur la base de ce critère, un grand nombre de genres bactériens ultérieurement reclassés avec l'avènement du séquençage et la découverte d'horloges moléculaires telle
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Simonin, Clémence. "De la stimulation cérébrale profonde à l’étude physiopathologique de certaines formes génétiques de la Maladie de Parkinson." Thesis, Lille 2, 2011. http://www.theses.fr/2011LIL2S032/document.

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Objectifs: D’une part étudier les effets de la SCP à moyen et long terme chez les patients de notre centre ayant une forme génétique de MP, d’autre part effectuer une étude clinique, génétique et transcriptomique d’un groupe de patients parkinsoniens ayant une mutation du gène SCA2 (dits patients SCA2).Méthode: 1/ Effet de la SCP chez des patients ayant une forme génétique de MP: cinq patients ayant une forme génétique de MP, appartenant à une cohorte de 52 patients parkinsoniens ayant bénéficié d’une stimulation à haute fréquence du noyau sous-thalamique entre 1998 et 2000, ont été examinés a
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Emmel, Vanessa Erichsen. "Análise de repetições CAG nos genes SCA1, SCA2, SCA3 e SCA6 em pacientes com suspeita clínica de ataxia espinocerebelar." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2007. http://hdl.handle.net/10183/10967.

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As ataxias espinocerebelares (SCAs) são doenças neurodegenerativas com herança autossômica dominante que apresentam grande heterogeneidade clínica e genética. O diagnóstico é realizado pela detecção da mutação no gene causador, que, na sua maioria, é uma expansão de repetições trinucleotídicas CAG. O objetivo deste estudo foi analisar os polimorfismos de repetições trinucleotídicas nos genes associados as SCAs tipo 1, tipo 2, tipo 3 e tipo 6 através de PCR-multiplex e eletroforese capilar, visando a melhoria do diagnóstico molecular e a determinação da distribuição das regiões polimórficas nos
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Åhlén, Johan. "Pilotstudie av FRIENDS : Ett preventionsprogram för ångestproblematik hos skolbarn." Thesis, Stockholm University, Department of Psychology, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-40651.

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<p>Ångestsyndrom tillhör den vanligaste psykiatriska problematiken hos barn. Ångestsyndrom börjar ofta i tidig ålder, medför stort lidande och predicerar psykiatrisk problematik senare i livet. Det är viktigt att undersöka hur ångestsyndrom kan förebyggas eftersom få barn med denna problematik kommer i kontakt med behandling. Syftet med studien var att undersöka om FRIENDS, ett preventionsprogram från Australien, fungerar i en svensk kontext. Femtio barn i nioårsåldern undervisades i FRIENDS under tio lektioner. Barnens ångestsymptom, depressionssymptom och generella psykiska hälsa mättes vid
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Books on the topic "Scas02"

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Gatti, Paula. Juan Antonio Scasso. IHA, 2009.

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Museo degli arazzi Scassa (Asti, Italy), ed. Museo degli arazzi Scassa. Skira, 2010.

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Scassa, Arazzeria, and Rocca di Umbertide, centro per l'arte contemporanea, eds. Scassa arazziere: L'arazzeria di Asti. Petruzzi, 2010.

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State Collaborative of Assessment and Student Standards. Health Education Assessment Project., Council of Chief State School Officers., and ToucanEd Publications (Firm), eds. Assessing health literacy: CCSSO-SCASS Health Education Project. ToucanEd Publications, 1999.

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Avanzo, Donatella. Da Kandinsky a Botero: Tutti in un filo : l'Arazzeria Scassa e l'arte del '900. Skira, 2018.

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(Firm), SWAT, and Institute of Chartered Accountants in England and Wales., eds. SCAS & VSCAS companies' accounts disclosure checklist. Accountancy Books, 1992.

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Assumpção, Paschoalino. O teatro amador em Santo André: A Sociedade de Cultura Artística (SCASA) e o Teatro de Alumínio. Alpharrabio Edições, 2000.

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Debra Faszer-McMahon; Victoria L. Ketz. African Immigrants in Contemporary Spanish Texts. Taylor & Francis, 2016.

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Theories and Practices of Development. Taylor & Francis Group, 2011.

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Theories and Practices of Development. Routledge, 2004.

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Book chapters on the topic "Scas02"

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de Vos, C. M., J. D. Bregman, and U. J. Schwarz. "Pupil Plane Interferometry: Some Conclusions from SCASIS." In Very High Angular Resolution Imaging. Springer Netherlands, 1994. http://dx.doi.org/10.1007/978-94-011-0880-5_85.

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Manto, Mario, and Christophe Habas. "Ataxies autosomales dominantes (SCAs)." In Le cervelet. Springer Paris, 2013. http://dx.doi.org/10.1007/978-2-8178-0447-7_23.

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Dempsey, Brian R., Anne C. Rintala-Dempsey, Gary S. Shaw, et al. "SKAP2/SCAP2 (Src Kinase-Associated Phosphoprotein 2)." In Encyclopedia of Signaling Molecules. Springer New York, 2012. http://dx.doi.org/10.1007/978-1-4419-0461-4_101241.

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Klir, George J. "Soft Computer-Aided System Theory and Technology (SCAST)." In Computer Aided Systems Theory — CAST '94. Springer Berlin Heidelberg, 1996. http://dx.doi.org/10.1007/3-540-61478-8_64.

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Vos, C. M., J. D. Bregman, and U. J. Schwarz. "SCASIS, Diffraction Limited Imaging using a Redundant Pupil Plane Interferometer." In Diffraction-Limited Imaging with Very Large Telescopes. Springer Netherlands, 1989. http://dx.doi.org/10.1007/978-94-009-2340-9_24.

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Hernández-Ferrándiz, Daniel, Juan J. Pantrigo, and Raul Cabido. "SCASA: From Synthetic to Real Computer-Aided Sperm Analysis." In Bio-inspired Systems and Applications: from Robotics to Ambient Intelligence. Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-031-06527-9_23.

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Mariotti, Caterina, Mario Fichera, and Lorenzo Nanetti. "How to Design a Therapeutic Trial in SCAs." In Contemporary Clinical Neuroscience. Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-24345-5_8.

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Zijlstra, Timo, Karim Bigou, and Arnaud Tisserand. "FPGA Implementation and Comparison of Protections Against SCAs for RLWE." In Lecture Notes in Computer Science. Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-35423-7_27.

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Batina, Lejla, Milena Djukanovic, Annelie Heuser, and Stjepan Picek. "It Started with Templates: The Future of Profiling in Side-Channel Analysis." In Security of Ubiquitous Computing Systems. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-10591-4_8.

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AbstractSide-channel attacks (SCAs) are powerful attacks based on the information obtained from the implementation of cryptographic devices. Profiling side-channel attacks has received a lot of attention in recent years due to the fact that this type of attack defines the worst-case security assumptions. The SCA community realized that the same approach is actually used in other domains in the form of supervised machine learning. Consequently, some researchers started experimenting with different machine learning techniques and evaluating their effectiveness in the SCA context. More recently,
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Waddington, G., S. Trathen, T. J. Dickson, R. Adams, and A. Rumore. "A Sport Concussion Assessment Tool (SCAT2) for Use in Snowsports: Can the Balance Component of the Tool Be Improved?" In Snow Sports Trauma and Safety. Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-52755-0_5.

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Conference papers on the topic "Scas02"

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Min, Wenwen, Zhen Wang, Fangfang Zhu, Taosheng Xu, Guangsheng Wu, and Shunfang Wang. "scASDC: Attention Enhanced Structural Deep Clustering for Single-cell RNA-seq Data." In 2024 IEEE International Conference on Bioinformatics and Biomedicine (BIBM). IEEE, 2024. https://doi.org/10.1109/bibm62325.2024.10822787.

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Guan, Xueyong, and Digby D. Macdonald. "Volume of Activation for the Corrosion of UNS S 30400 in High Subcritical and Supercritical Aqueous Systems." In CORROSION 2007. NACE International, 2007. https://doi.org/10.5006/c2007-07407.

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Abstract In this study electrochemical noise analysis (ENA) is used to analyze the effect of pressure on corrosion reactions in high subcritical and supercritical aqueous systems (SCAS). A model is applied to study the effect of pressure on corrosion rates of metals in SCAS, with emphasis on contributions from activation, the degree of dissociations of aggressive species, and the system isothermal compressibility. Experiments were carried out to estimate the pressure dependencies of the electrochemical corrosion rates of UNS S 30400 (Type 304 SS) in HCl at subcritical and supercritical tempera
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Shue, Shyhpyng, Eric Carlson, John Schillings, and Mike Bothwell. "OH-58 Block II Control Law Upgrades." In Vertical Flight Society 70th Annual Forum & Technology Display. The Vertical Flight Society, 2014. http://dx.doi.org/10.4050/f-0070-2014-9667.

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The Bell Helicopter OH-58 Block II Concept Demonstrator was developed under an internal research and development program. In 2011, the Block II aircraft demonstrated HOGE Performance at 6000 ft pressure altitude, 95 degrees Fahrenheit (6k95F), for test conditions that exceeded the maximum gross weight. As part of the overall development program, the OH-58D baseline control laws were updated to improve handling qualities. This paper describes the control law changes and the resulting improved handling qualities. VMS studies were initiated to assess the main rotor cyclic actuator arrangement. CI
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Wu, Jiejian, Linghe Kong, Haifeng Tang, and Tom Z. J. Fu. "SCASys." In SIGCOMM '21: ACM SIGCOMM 2021 Conference. ACM, 2021. http://dx.doi.org/10.1145/3472716.3472857.

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"SCA2012 Organizing and Program Committees." In 2012 International Conference on Cloud and Green Computing (CGC). IEEE, 2012. http://dx.doi.org/10.1109/cgc.2012.7.

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"Message from the SCA2012 Chairs." In 2012 International Conference on Cloud and Green Computing (CGC). IEEE, 2012. http://dx.doi.org/10.1109/cgc.2012.5.

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Steadman, Matt, and Steve Adler. "SCAsat Audio Distribution “Best of Satellite, Best of WAN”." In SMPTE Australia Conference. IEEE, 2015. http://dx.doi.org/10.5594/m001603.

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Kbar, Ghassan, Shady Aly, and Bhaa Alhanafi. "Smart and Context Aware Search for University Campus (SCASUC)." In 2012 International Conference on Multimedia Computing and Systems (ICMCS). IEEE, 2012. http://dx.doi.org/10.1109/icmcs.2012.6320141.

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Bandara, Nalin, Kosala Gunawardane, and Nihal Kularatna. "Exprimental verification of Supercapacitor Assisted Sub Module Inverter (SCASMI) Technique." In 2020 2nd IEEE International Conference on Industrial Electronics for Sustainable Energy Systems (IESES). IEEE, 2020. http://dx.doi.org/10.1109/ieses45645.2020.9210666.

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Uddin, Md Yusuf Sarwar, Alexander Nelson, Kyle Benson, et al. "The Scale2 Multi-Network Architecture for IoT-Based Resilient Communities." In 2016 IEEE International Conference on Smart Computing (SMARTCOMP). IEEE, 2016. http://dx.doi.org/10.1109/smartcomp.2016.7501722.

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