Relevant bibliographies by topics / Scopolamine and antioxidant

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  1. Journal articles
  2. Dissertations / Theses
  3. Book chapters

Academic literature on the topic 'Scopolamine and antioxidant'

Author: Grafiati
Published: 3 June 2025
Last updated: 31 July 2025

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Journal articles on the topic "Scopolamine and antioxidant"

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Neeraj, Kumar* Chetna Dhiman Preeti Kothiyal. "EVALUATION OF ANETHUM GRAVEOLENS EXTRACT ON MEMORY IMPAIRED MICE." Indo American Journal of Pharmaceutical Sciences 04, no. 07 (2017): 1965–75. https://doi.org/10.5281/zenodo.833451.

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Objective:The objective of this study was to evaluate the effect of Anethum graveolens (Dill) extract on scopolamine induced learning and memory impairment in mice. The antioxidant property of Anethum graveolens was evaluated. Material and methods: A total of 36 mice (25-30 g) were randomized into 6 equal groups. Memory enhancing activity of Anethum graveolens in amnesic mice was investigated by using Elevated plus maze and Morris water maze. AchE activity, SOD and lipid peroxidation of brain homogenate were performed in control/ scopolamine/ standard / Anethum graveolens leaves extract treate
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Balakrishnan, Rengasamy, Ju-Young Park, Duk-Yeon Cho та ін. "AD−1 Small Molecule Improves Learning and Memory Function in Scopolamine-Induced Amnesic Mice Model through Regulation of CREB/BDNF and NF-κB/MAPK Signaling Pathway". Antioxidants 12, № 3 (2023): 648. http://dx.doi.org/10.3390/antiox12030648.

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Cognitive decline and memory impairment induced by oxidative brain damage are the critical pathological hallmarks of Alzheimer’s disease (AD). Based on the potential neuroprotective effects of AD−1 small molecule, we here explored the possible underlying mechanisms of the protective effect of AD-1 small molecule against scopolamine-induced oxidative stress, neuroinflammation, and neuronal apoptosis. According to our findings, scopolamine administration resulted in increased AChE activity, MDA levels, and decreased antioxidant enzymes, as well as the downregulation of the antioxidant response p
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Ankita, Bhardwaj*and Suruti Rawat. "INVESTIGATION OF GLIMEPIRIDE IN STREPTOZOTOCIN AND SCOPOLAMINE INDUCED LEARNING AND MEMORY IMPAIRMENT IN RATS." Indo American Journal of Pharmaceutical Sciences 04, no. 08 (2017): 2564–73. https://doi.org/10.5281/zenodo.852485.

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The present study was designed to evaluate the therapeutic potential of Glimepiride in Streptozotocin and Scopolamine induced Learning and Memory Impairment in Rats. Memory enhancing activity of glimepiride in STZ and scopolamine induced learning and memory impairment in rats was investigated by using Morris water maze. SOD, lipid peroxidation, glutathione level of brain homogenate was performed.Rats were randomly assigned to 9 groups (n = 6 each group): (1-5 Groups): control, STZ (60 mg/kg i.p.), insulin (0.5 Units insulin per 100gm body weight), Glimepiride (5 and 10 mg/kg, p.o.) for 28 days
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Ishola, Ismail O., Taiwo G. Olubodun-Obadun, Mariam A. Ojulari, and Olufunmilayo O. Adeyemi. "Rutin ameliorates scopolamine-induced learning and memory impairments through enhancement of antioxidant defense system and cholinergic signaling." Drug Metabolism and Drug Interactions 36, no. 1 (2020): 53–61. http://dx.doi.org/10.1515/dmpt-2020-0118.

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Abstract Objectives The brain’s cholinergic system occupies a central role in normal cognition and age-related cognitive decline, including Alzheimer’s disease (AD). This study sought to investigate the role of antioxidant defense and cholinergic systems on rutin-induced antiamnesia in mice. Methods Rutin (1, 5, or 50 mg/kg, p.o.) or vehicle (10 ml/kg, p.o.) was administered for three consecutive days. One hour post-treatment on day 3, scopolamine (3 mg/kg, i.p) was given, 5 min post-scopolamine injection, open field, Y-maze, or Morris water maze (MWM) (five days consecutive training sessions)
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Todirascu-Ciornea, Elena, Heba A. S. El-Nashar, Nada M. Mostafa, et al. "Schinus terebinthifolius Essential Oil Attenuates Scopolamine-Induced Memory Deficits via Cholinergic Modulation and Antioxidant Properties in a Zebrafish Model." Evidence-Based Complementary and Alternative Medicine 2019 (December 2, 2019): 1–11. http://dx.doi.org/10.1155/2019/5256781.

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Schinus terebinthifolius is a plant well recognized for its therapeutic profile such as anti-inflammatory and antitumor activities, promoting antibacterial activity and antioxidant and antidiabetic properties. This study aimed at examining whether Schinus terebinthifolius memory-enhancing activities are mediated by cholinergic and brain antioxidant systems in a scopolamine zebrafish model. Schinus terebinthifolius essential oil (10, 25, and 50 μL/L) was delivered to zebrafish by immersion in water for 8 days. Memory deficits were induced by scopolamine (100 μM) administration. Zebrafish were d
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Biradar, SM, H. Joshi, and TK Chheda. "Biochanin-A ameliorates behavioural and neurochemical derangements in cognitive-deficit mice for the betterment of Alzheimer’s disease." Human & Experimental Toxicology 33, no. 4 (2013): 369–82. http://dx.doi.org/10.1177/0960327113497772.

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Biochanin-A (BCA), a potent phytoconstituent, has been previously used as an antitumour, a dopaminergic neuron protective agent, an antioxidant, an anticholinergic and on other pharmacological activities including neuroprotection. The present study was aimed to evaluate the behavioural and neurochemical evidence of BCA in cognitive-deficit mice in scopolamine challenged and natural aged-induced amnesia models in young and aged mice, respectively. BCA has exhibited decrease in the transfer latency and increase in step through latency significantly ( p < 0.001) in scopolamine-treated and natu
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Thangnipon, Wipawan, Sukonthar Ngampramuan, Nopparat Suthprasertporn, Chanati Jantrachotechatchawan, Patoomratana Tuchinda, and Saksit Nobsathian. "Protective Roles of N-trans-feruloyltyramine Against Scopolamine-Induced Cholinergic Dysfunction on Cortex and Hippocampus of Rat Brains." Siriraj Medical Journal 73, no. 6 (2021): 413–22. http://dx.doi.org/10.33192/smj.2021.55.

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Objective: To study the protective effects of N-trans-feruloyltyramine (NTF) on scopolamine-induced cholinergic dysfunction, apoptosis, and inflammation in rat brains. Materials and Methods: Treatments were administered intraperitoneally (i.p.). Wistar rats (8-week-old) were allocated into 4 groups (n = 3) as follows: scopolamine-only, NTF-only, NTF + scopolamine and control. Spatial cognition was evaluated by Morris water maze. ROS assay and Western blot analyses were conducted in 3 brain regions: the frontal cortex, hippocampus, and temporal cortex. Results: NTF treatment inhibited scopolami
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Ashiekaa, Moses Ternenge, Innocent Abi, Aver Maria Yongu, Sunday Adakole Ogli, and Olasupo Stephen Adeniyi. "Scopolamine-induced brain injury and lipid peroxidation in Wistar rats ameliorated by garlic oil supplementation." Journal of African Association of Physiological Sciences 12, no. 1 (2024): 10–18. http://dx.doi.org/10.4314/jaaps.v12i1.2.

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Background: Scopolamine induced toxicity has been linked to impaired learning and memory, lipid peroxidation, oxidative stress and impairment of cholinergic transmission resulting in brain injury; which are synonymous with features of neurodegenerative diseases such as Alzheimer’s disease. Garlic oil has been found to be a possible therapeutic intervention. Its antioxidant and anticholinesterase activity were evaluated in scopolamine-induced brain toxicity in Wistar rats.Methods: The animals were grouped into seven groups (n=5). Group I (Normal Control) was given 1mL/kg distilled water for 14d
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Capatina, Luminita, Razvan Stefan Boiangiu, Gabriela Dumitru, et al. "Rosmarinus officinalis Essential Oil Improves Scopolamine-Induced Neurobehavioral Changes via Restoration of Cholinergic Function and Brain Antioxidant Status in Zebrafish (Danio rerio)." Antioxidants 9, no. 1 (2020): 62. http://dx.doi.org/10.3390/antiox9010062.

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Rosmarinus officinalis L. is a traditional herb with various therapeutic applications such as antibacterial, antioxidant, anti-inflammatory, antidepressant, and anticholinesterase activities, and can be used for the prevention or treatment of dementia. In the present study, we tested whether Rosmarinus officinalis L. could counteract scopolamine-induced anxiety, dementia, and brain oxidative stress in the zebrafish model and tried to find the underlying mechanism. Rosmarinus officinalis L. essential oil (REO: 25, 150, and 300 µL/L) was administered by immersion to zebrafish (Danio rerio) once
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Razuvaeva, Yanina G., Kristina V. Markova, Anyuta A. Toropova, Nina I. Kashchenko, and Daniil N. Olennikov. "Chemical Constituents, Neuroprotective and Antioxidant Potential of Klasea centauroides Leaves." Applied Sciences 13, no. 2 (2023): 860. http://dx.doi.org/10.3390/app13020860.

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Owing to progressive aging in the population, there is an increase in patients with cognitive impairment. For the prevention of dementia, the use of plant remedies is relevant. Of particular interest is Klasea centauroides (L.) Cass. (Serratula centauroides L., Asteraceae), which has significant natural reserves, contains a wide range of biologically active substances, and is used in folk medicine to treat nervous system diseases. This study aimed to estimate the neuroprotective, energy-protective, and antioxidant effects of K. centauroides extract in cholinergic deficiency caused by long-term
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Dissertations / Theses on the topic "Scopolamine and antioxidant"

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Martins, Daniele Moreira. "Ação Antioxidante e Neuroprotetora de Derivados Pirazolínicos Inéditos." Universidade Federal de Santa Maria, 2008. http://repositorio.ufsm.br/handle/1/8944.

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior<br>Oxidative stress is involved in several neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease and amyotrophic lateral sclerosis. Oxidative stress seems to be involved in the pathology of dementia/amnesia. It has been suggested that oxidative stress impairs the muscarinic cholinergic system triggering Alzheimer's disease. The muscarinic antagonist scopolamine has been used to induce amnesia in animals. This experimental model has been used in screening anti-amnesic drugs that could be useful for the treatment
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Book chapters on the topic "Scopolamine and antioxidant"

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Tafese Awulachew, Melaku. "Pharmacological, Biopesticide, and Post-Harvest Loss Management Application of Jimsonweed (Datura stramonium)." In Medicinal Plants [Working Title]. IntechOpen, 2022. http://dx.doi.org/10.5772/intechopen.102789.

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Datura stramonium is one of the most intriguing, in part because of its well-known therapeutic and psychoactive properties in the treatment of many diseases. Datura species have been found to exhibit a variety of biological activity. Insecticide, fungicide, antioxidant, antibacterial, hypoglycemic, and immune response boosting properties have been linked to the genus’ species. These effects are linked to the existence of secondary metabolites such as terpenoids, flavonoids, with anolides, tannins, phenolic compounds, and tropane alkaloids, which are the most prevalent atropine and scopolamine
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Journal articles
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