Academic literature on the topic 'Self-emulsifying drug delivery systems'

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Journal articles on the topic "Self-emulsifying drug delivery systems"

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Блынская, E. Blynskaya, Турчинская, et al. "The Technology of Self-Emulsifying Drug Delivery Systems." Journal of New Medical Technologies 21, no. 1 (2014): 128–33. http://dx.doi.org/10.12737/3320.

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Nearly 40% of novel chemical entities show evidence of low solubility in water and low bioavailability. Self-emulsifying formulations have showed the power to improve the bioavailability of hydrophobic drugs. Self-emulsifying formulations belong to lipid formulations, and their size range from 100 nm in case of self-emulsifying drug delivery systems and less than 50 nm in case of self-microemulsifying drug delivery systems. In general self-emulsifying formulations s represent isotropic mixtures of oils, surfactants and co-surfactants, which emulsify spontaneous in aqueous media under condition
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Kadian, Renu, and Arun Nanda. "A Comprehensive Insight on Self Emulsifying Drug Delivery Systems." Recent Advances in Drug Delivery and Formulation 16, no. 1 (2022): 15–43. http://dx.doi.org/10.2174/2667387815666211207112803.

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Background: The oral route is a highly recommended route for the delivery of a drug. But most lipophilic drugs are difficult to deliver via this route due to their low aqueous solubility. Selfemulsifying drug delivery systems (SEDDS) have emerged as a potential approach of increasing dissolution of a hydrophobic drug due to spontaneous dispersion in micron or nano sized globules in the GI tract under mild agitation. Objective: The main motive of this review article is to describe the mechanisms, advantages, disadvantages, factors affecting, effects of excipients, possible mechanisms of enhanci
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N., Likitha, and Sandeep K. "Self Emulsifying Drug Delivery System." International Journal of Innovative Science and Research Technology 7, no. 11 (2022): 33–40. https://doi.org/10.5281/zenodo.7319153.

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Self-emulsifying drug delivery systems (SEEDS) are mixtures of perfect isotropic oils and surfactants, with or without cosolvents, that emulsify when gently agitated, similar to the conditions found in the gastrointestinal tract. These systems cause the gastro-intestinal tract (GIT) to mildly agitate while forming fine emulsions (or micro-emulsions). The oral absorption of drugs from SEEDS is greatly influenced by a number of factors, including surfactant concentration, oil/surfactant ratio, polarity of the emulsion, droplet size, and charge. This formulation improves bioavailability by increa
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Hamzah, Mohammed Layth, Hanan J. Kassab, and Laith Hamza Samein. "Self-Nano Emulsifying Drug Delivery Systems." Journal of medical pharmaceutical and allied sciences 11, no. 1 (2022): 4205–13. http://dx.doi.org/10.55522/jmpas.v11i1.1388.

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Lipid-based medication conveyance frameworks are widely announced in the writing for improving medication solvency, penetrability, and bioavailability. These frameworks incorporate straightforward oil arrangements, coarse, numerous, and dry emulsions, complex self-emulsifying, miniature emulsifying, or nano emulsifying drug conveyance frameworks. Self-emulsifying frameworks, further named self-miniature emulsifying drug conveyance frameworks (SMEDDS) and self-nano emulsifying drug conveyance frameworks (SNEDDS), are the most overall and economically feasible oil-based methodology for drugs tha
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Reza, Jamilur. "Self-Emulsifying Drug Delivery Systems: A Review." International Journal of Pharmaceutical and Life Sciences 2, no. 2 (2013): 80–84. http://dx.doi.org/10.3329/ijpls.v2i2.15453.

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Self-emulsifying drug delivery systems (SEDDS) possess unparalleled potential in improving oral bioavailability of poorly water-soluble or lipophilic drugs. Following their oral administration, these systems rapidly disperse in gastrointestinal fluids, yielding micro- or nanoemulsions containing the solubilized drug. Owing to its miniscule globule size, the micro/nanoemulsified drug can easily be absorbed through lymphatic pathways, bypassing the hepatic first-pass effect. But it has drawbacks as formulation development, quality control, stability etc. These liquid SEDDS can be converted into
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Deepshikha, Kukde, and Bharkatiya Meenakshi. "Self-emulsifying Drug Delivery System: An Overview with Novel Perspective." Pharmaceutical and Chemical Journal 9, no. 2 (2022): 77–89. https://doi.org/10.5281/zenodo.13970481.

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Self-emulsifying drug delivery systems, which are isotropic mixtures of oils, surfactants, solvents, and co-solvents or surfactants, may be used to design formulations to boost oral absorption of highly lipophilic drug compounds. It may be orally administered in soft or hard gelatin capsules. These systems form fine emulsions or micro-emulsions in the gastro-intestinal tract with mild agitation provided by gastric mobility. These formulations were increased bioavailability due to increasing the solubility of the drug and minimize gastric irritation. The very fact is that almost 40% of the new
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Gupta, Shweta, Rajesh Kesarla, and Abdelwahab Omri. "Formulation Strategies to Improve the Bioavailability of Poorly Absorbed Drugs with Special Emphasis on Self-Emulsifying Systems." ISRN Pharmaceutics 2013 (December 26, 2013): 1–16. http://dx.doi.org/10.1155/2013/848043.

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Poorly water-soluble drug candidates are becoming more prevalent. It has been estimated that approximately 60–70% of the drug molecules are insufficiently soluble in aqueous media and/or have very low permeability to allow for their adequate and reproducible absorption from the gastrointestinal tract (GIT) following oral administration. Formulation scientists have to adopt various strategies to enhance their absorption. Lipidic formulations are found to be a promising approach to combat the challenges. In this review article, potential advantages and drawbacks of various conventional technique
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Reddy, Sunitha M., and Sravani Baskarla. "A Review on Formulation and Development of Solid Self-Nano Emulsifying Drug Delivery Systems." International Journal of Pharmaceutical Sciences and Nanotechnology 14, no. 4 (2021): 5519–228. http://dx.doi.org/10.37285/ijpsn.2021.14.4.1.

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This article describes current strategies to enhance aqueous solubility and dissolution rate of poor soluble drugs. Most drugs in the market are lipophilic with low or poor water solubility. There are various methods to enhance solubility: co-solvency, particle size reduction, salt formation and Self Nanoemulsifying drug delivery systems, SEDDS is a novel approach to enhance solubility, dissolution rate and bioavailability of drugs. The study involves formulation and evaluation of solid self-Nano emulsifying drug delivery system (S-SNEDDS) to enhance aqueous solubility and dissolution rate. Or
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Pouton, Colin W. "Formulation of self-emulsifying drug delivery systems." Advanced Drug Delivery Reviews 25, no. 1 (1997): 47–58. http://dx.doi.org/10.1016/s0169-409x(96)00490-5.

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Raut, Sayali, Firoj Tamboli, Harinath More, Aishwarya Kulkarni, and Nitin Kokare. "Self-emulsifying drug delivery systems: An overview." International Journal of Pharmacy and Pharmaceutical Science 3, no. 1 (2021): 05–08. http://dx.doi.org/10.33545/26647222.2021.v3.i1a.16.

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Dissertations / Theses on the topic "Self-emulsifying drug delivery systems"

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Wakerly, M. G. "Self-emulsifying drug delivery systems based on nonionic surfactant-oil mixtures." Thesis, University of Bath, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.235402.

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Patel, Manisha Jagdishchandra. "The formulation and characterisation of polyglycolysed glyceride self-emulsifying drug delivery systems." Thesis, University College London (University of London), 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.326220.

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Challis, Deborah. "Physicochemical and biopharmaceutical studies of novel self-emulsifying systems for administration by the oral route (SEDDS)." Thesis, University of Bath, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.280871.

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Mercuri, Annalisa. "A Physico-Chemocal Investigation into the Factors Affecting the Behaviour of Self-Emulsifying Drug Delivery Systems." Thesis, University of East Anglia, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.518385.

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The aim of this work was to investigate the relationship between drug-loading and self-emulsification. Several techniques were used to assess the physico-chemical properties of a self-emulsifying formulation formed by GRAS listed excipients with and without a model drug. The micropolarity at the droplet interface was found to be related to the HLB of the surfactant mixtures and it was shown to increase when the drug ibuprofen (6% w/w) was present. IH-NMR showed that this is due to the preferred solubilisation site of the drug; in fact, surfactant-like drugs preferably solubilise at the palisad
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Zhao, Tianjing. "Self-nanoemulsifying drug delivery systems (SNEDDS) for the oral delivery of lipophilic drugs." Doctoral thesis, University of Trento, 2015. http://eprints-phd.biblio.unitn.it/1608/1/Doctoral_thesis-Self-nanoemulsifying_drug_delivery_systems_(SNEDDS)_for_the_oral_delivery_of_lipophilic_drugs-Tianjing_ZHAO.pdf.

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The increasing number of lipophilic drug candidates in development in the pharmaceutical industry calls for advanced drug delivery systems with increased bioavailability less day-to-day and food-intake-dependent. Many of these drug candidates possess poor water solubility, so that their dissolution rate in the gastrointestinal tract (GIT) limits their absorption following oral administration. In the past few decades, various lipid-based formulations have been investigated to enhance the bioavailability of such challenging drug candidates and to increase their clinical efficacy when administer
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Zhao, Tianjing. "Self-nanoemulsifying drug delivery systems (SNEDDS) for the oral delivery of lipophilic drugs." Doctoral thesis, Università degli studi di Trento, 2015. https://hdl.handle.net/11572/369035.

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The increasing number of lipophilic drug candidates in development in the pharmaceutical industry calls for advanced drug delivery systems with increased bioavailability less day-to-day and food-intake-dependent. Many of these drug candidates possess poor water solubility, so that their dissolution rate in the gastrointestinal tract (GIT) limits their absorption following oral administration. In the past few decades, various lipid-based formulations have been investigated to enhance the bioavailability of such challenging drug candidates and to increase their clinical efficacy when administere
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Aldosari, Basmah Nasser Abdullah. "Development and evaluation of self-nanoemulsifying drug delivery systems for oral delivery of indomethacin." Thesis, University College London (University of London), 2018. http://discovery.ucl.ac.uk/10044225/.

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In this study, indomethacin-loaded self-nanoemulsifying drug delivery systems (SNEDDS) were developed in liquid, solid and carrier-mediated formulations in order to improve the solubility of this model poorly water soluble drug. Liquid SNEDDS based on CapryolTM 90 (oil phase), Cremophor® RH 40 (surfactant) and Transcutol® HP (co-surfactant) were thermodynamically stable and produced clear nanoemulsions upon dilution. Optimized liquid formulations were transformed into solid SNEDDS by adsorption onto the inert carriers Syloid® XDP 3150, Neusilin® US2 and Florite® PS-200. Ratios of adsorbent: li
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Wood, Kris Cameron. "Nanostructured gene and drug delivery systems based on molecular self-assembly." Thesis, Massachusetts Institute of Technology, 2007. http://hdl.handle.net/1721.1/39350.

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Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemical Engineering, 2007.<br>Includes bibliographical references.<br>Molecular self-assembly describes the assembly of molecular components into complex, supramolecular structures governed by weak, non-covalent interactions. In recent years, molecular self-assembly has been used extensively as a means of creating materials and devices with well-controlled, nanometer-scale architectural features. In this thesis, molecular self-assembly is used as a tool for the fabrication of both gene and drug delivery systems which, by virtue
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Wang, Han. "Developing Novel Drug Delivery Systems For Platinum-based Anticancer Drugs Using Coordination-driven Self-assembly." Kent State University / OhioLINK, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=kent1595260147978142.

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Michaelsen, Maria Høtoft. "The effect of digestion and drug load on absorption of poorly water soluble drugs from self-nanoemulsifying drug delivery systems (SNEDDS)." Thesis, University of British Columbia, 2016. http://hdl.handle.net/2429/59178.

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Books on the topic "Self-emulsifying drug delivery systems"

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Singh, Sachin Kumar, Samir Mehndiratta, Keshav Raj Paudel, Gabriele De Rubis, Harish Dureja, and Kamal Dua. Application of Self-Nanoemulsifying Drug Delivery Systems in Inflammatory Diseases. CRC Press, 2025. https://doi.org/10.1201/9781032697475.

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V, Kabanov Alexander, Felgner Philip L. 1950-, and Seymour L. W, eds. Self-assembling complexes for gene delivery: From laboratory to clinical trial. Wiley, 1998.

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Kaushik, Deepak, and Ravinder Verma. Comprehensive Text Book on Self-Emulsifying Drug Delivery Systems. Bentham Science Publishers, 2021.

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Ravinder, Deepak Kaushik;. Comprehensive Text Book on Self-Emulsifying Drug Delivery Systems. Bentham Science Publishers, 2021.

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Comprehensive Text Book on Self-Emulsifying Drug Delivery Systems. Bentham Science Publishers, 2021.

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Shelake, Priyanka, Vidya Nalawade, and Priyanka Majalekar. Solid self-emulsifying drug delivery system: Formulation & evaluation of solid self-emulsifying drug delivery BCS class II drug Mirtazipine. LAP Lambert Academic Publishing, 2020.

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Kaushik, Deepak, and Ravinder Verma, eds. A Comprehensive Text Book on Self-emulsifying Drug Delivery Systems. BENTHAM SCIENCE PUBLISHERS, 2021. http://dx.doi.org/10.2174/97898149980001210101.

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Wadhwa, Jyoti. Self Emulsifying Drug Delivery Systems: A Formulation Approach for Poorly Soluble Drugs. LAP Lambert Academic Publishing, 2011.

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Chandrakant, Mahajan Kiran. Formulation and Optimization of Self Emulsifying Drug Delivery System for Effective Anthelmintic Therapy. Quadry, Fatima, 2023.

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Pulsed and self-regulated drug delivery. CRC Press, 1990.

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Book chapters on the topic "Self-emulsifying drug delivery systems"

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Penchala, Sravan, Anh-Nhan Pham, Ying Huang, and Jeffrey Wang. "Lipid-Based and Self-Emulsifying Oral Drug Delivery Systems." In Oral Bioavailability. John Wiley & Sons, Inc., 2011. http://dx.doi.org/10.1002/9781118067598.ch21.

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Chalikwar, Shailesh S., Pankaj V. Dangre, Poorva P. Dusad, and Sanjay J. Surana. "Self-Emulsifying Drug Delivery System for Potential Nutraceuticals: Solidification Techniques and Quality by Design (QbD)." In Nutraceutical Delivery Systems. Apple Academic Press, 2022. http://dx.doi.org/10.1201/9781003189671-12.

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Fatouros, Dimitrios G., and Anette Müllertz. "Development of Self-Emulsifying Drug Delivery Systems (SEDDS) for Oral Bioavailability Enhancement of Poorly Soluble Drugs." In Drug Delivery Strategies for Poorly Water-Soluble Drugs. John Wiley & Sons Ltd, 2013. http://dx.doi.org/10.1002/9781118444726.ch7.

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Banerjee, Ankita, Rajesh Kumar, Monica Gulati, et al. "Self-Emulsifying Drug Delivery Systems: A Strategy to Improve the Bioavailability of Hydrophobic Drugs." In The Era of Nanotechnology. Apple Academic Press, 2021. http://dx.doi.org/10.1201/9781003160588-6.

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Vishwas, Sukriti, Rubiya Khursheed, Sheetu Wadhwa, et al. "Mechanisms of Drug Delivery in Self-Nanoemulsifying Drug Delivery Systems." In Application of Self-Nanoemulsifying Drug Delivery Systems in Inflammatory Diseases. CRC Press, 2025. https://doi.org/10.1201/9781032697475-5.

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Khang, Gil Son, Jae Chan Yang, Jong Tae Ko, et al. "Preparation and Characterization of Ibuprofen Using Self-Emulsifying Drug Delivery System In Vivo." In Advanced Biomaterials VII. Trans Tech Publications Ltd., 2007. http://dx.doi.org/10.4028/0-87849-436-7.541.

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Sailor, Girish U. "Self-Nanoemulsifying Drug Delivery Systems (SNEDDS): An Innovative Approach to Improve Oral Bioavailability." In Nanocarriers: Drug Delivery System. Springer Singapore, 2021. http://dx.doi.org/10.1007/978-981-33-4497-6_10.

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Pandey, Divya, Smriti Bhardwaj, and Kuldeep K. Roy. "Self-Nanoemulsifying Drug Delivery Systems for Oral Anticancer Drugs." In Application of Self-Nanoemulsifying Drug Delivery Systems in Inflammatory Diseases. CRC Press, 2025. https://doi.org/10.1201/9781032697475-13.

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Molehin, Olorunfemi R., Adeniyi S. Ohunayo, Oluwasegun S. Dauda, John O. Teibo, and Adeyemi S. Akinlamilo. "Self-Nanoemulsifying Drug Delivery Systems (SNEDDS) in Diabetes." In Application of Self-Nanoemulsifying Drug Delivery Systems in Inflammatory Diseases. CRC Press, 2025. https://doi.org/10.1201/9781032697475-8.

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Thirugnanasambandham, Indhumathi, Gowthamarajan Kuppusamy, Ruchika Ajay, et al. "Toxicological Considerations in Self-Nanoemulsifying Drug Delivery Systems." In Application of Self-Nanoemulsifying Drug Delivery Systems in Inflammatory Diseases. CRC Press, 2025. https://doi.org/10.1201/9781032697475-17.

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Conference papers on the topic "Self-emulsifying drug delivery systems"

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Venkatesh, S., R. Preethi, B. Revathi, R. Dhanya, and B. Sachuthananthan. "A Review on Human Respiratory Model Development for Drug Delivery." In 2024 2nd International Conference on Self Sustainable Artificial Intelligence Systems (ICSSAS). IEEE, 2024. http://dx.doi.org/10.1109/icssas64001.2024.10760678.

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Du, Zhiyuan, Qingda Xu, Ye Xi, et al. "An Implantable Nanoelectrode for Simultaneous in-Situ Self-Referencing, Drug Delivery, and Reliable Fixed-Point Recording Within a Single Neuron." In 2025 IEEE 38th International Conference on Micro Electro Mechanical Systems (MEMS). IEEE, 2025. https://doi.org/10.1109/mems61431.2025.10917494.

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Krzeminska, Katarzyna, and Malgorzata Sznitowska. "Stability studies of cefuroxime loaded self-emulsifying drug delivery systems for ocular administration." In IV. Symposium of Young Researchers on Pharmaceutical Technology,Biotechnology and Regulatory Science. Institute of Pharmaceutical Technology and Regulatory Affairs, University of Szeged, Faculty of Pharmacy, 2022. http://dx.doi.org/10.14232/syrptbrs.2022.25.

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Ermawati, Dian Eka, Roro Karina Pambudi, Vinda Aviwiandari, et al. "Developing formula of SNEDDS (self nano emulsifying drug delivery system) antihypertensive herbals “Hortus Medicus”." In THE 14TH JOINT CONFERENCE ON CHEMISTRY 2019. AIP Publishing, 2020. http://dx.doi.org/10.1063/5.0005630.

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Putri, Sri Ainaiyah Ariadi, Sunaryono Sunaryono, Nadiya Miftachul Chusna, Nasikhuddin Nasikhuddin, and Kormil Saputra. "Study of antioxidant of self nano emulsifying drug delivery system (SNEDDS)- Fe3O4/ginger extract ferrofluid." In THE 4TH MATERIALS RESEARCH SOCIETY OF INDONESIA (MRS-ID) MEETING. AIP Publishing, 2025. https://doi.org/10.1063/5.0240583.

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Buddhadev, Sheetal, and Kevin Garala. "Self-Nano Emulsifying Drug-Delivery Systems: From the Development to The Current Applications and Update of the Biopharmaceutical Aspect." In 1st International Electronic Conference on Biomedicine. MDPI, 2021. http://dx.doi.org/10.3390/ecb2021-10296.

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Hayati, Farida, Lutfi Chabib, and Diah Dwi Darma. "Antihyperglycemia activity of self-nano emulsifying drug-delivery systems (SNEDDS) of Ipomoea reptans, Poir leaf ethanolic extract in zebrafish (Danio rerio)." In 2ND INTERNATIONAL CONFERENCE ON CHEMISTRY, CHEMICAL PROCESS AND ENGINEERING (IC3PE). Author(s), 2018. http://dx.doi.org/10.1063/1.5064986.

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Syukri, Yandi, Bambang Hernawan Nugroho, and Muhammad Sirin. "Determination of andrographolide content in self nano emulsifying drug delivery system (SNEDDS) for in vitro diffusion study using validated HPLC." In PROCEEDINGS OF THE 3RD INTERNATIONAL SEMINAR ON METALLURGY AND MATERIALS (ISMM2019): Exploring New Innovation in Metallurgy and Materials. AIP Publishing, 2020. http://dx.doi.org/10.1063/5.0002446.

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Divetia, Asheesh, Nolan Yoshimura, Guann-Pynn Li, Baruch D. Kuppermann, and Mark Bachman. "Controlled and Programmable Drug Delivery Using a Self-Powered MEMS Device." In ASME 2007 2nd Frontiers in Biomedical Devices Conference. ASMEDC, 2007. http://dx.doi.org/10.1115/biomed2007-38054.

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Controlled and targeted drug delivery systems have gained a lot of interest as they offer numerous benefits such as precise dosing, reduced side-effects and increased patient compliance. We have designed a microelectromechanical systems (MEMS) drug delivery device that is capable of releasing drugs in a controlled and programmable manner. This self-powered device does not require any external stimulation or control to achieve pulsatile release of drugs. The device consists of multiple reservoirs containing the drug embedded together with a water-swellable polymer. The swelling of the polymer u
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Nottingham, Ebony, Vasanth Sekar, Arindam Mondal, and Mandip Sachdeva. "Abstract 2039: The use of self nano-emulsifying drug delivery systems to improve bioavailability of combination therapy and overcome erlotinib resistance in non-small cell lung cancer." In Proceedings: AACR Annual Meeting 2017; April 1-5, 2017; Washington, DC. American Association for Cancer Research, 2017. http://dx.doi.org/10.1158/1538-7445.am2017-2039.

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Reports on the topic "Self-emulsifying drug delivery systems"

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Chakraborty, Payel, and Tamilvanan Shunmugaperumal. Simvastatin repurposing towards endometriosis management: The use of self -nanoemulsifying drug delivery system. Peeref, 2023. http://dx.doi.org/10.54985/peeref.2304p6131285.

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