Academic literature on the topic 'Selfnano emulsifying drug delivery system (SNEDDS)'

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Journal articles on the topic "Selfnano emulsifying drug delivery system (SNEDDS)"

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Vishakha, Vishwanath Doke, M. Khutle Nilesh, Sharma Maya, and Gupta Khemchand. "Solubility Enhancement of Poorly Soluble Drug Ezetimibe by Developing Self Nano Emulsifying Drug Delivery System." Indian Journal of Science and Technology 15, no. 30 (2022): 1504–16. https://doi.org/10.17485/IJST/v15i30.582.

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Abstract <strong>Objectives:</strong>&nbsp;To enhance solubility, dissolution, and permeability of poorly water-soluble drug Ezetimibe (EZE) using a self-nano emulsifying drug delivery system (SNEDDS).&nbsp;<strong>Methods:</strong>&nbsp;Initially, the solubility of the EZE was determined in various oils and buffers. Surfactants and co-surfactants were screened based on the solubility of the drug in oil as per the emulsification efficacy test. Liquid SNEDDS was developed and characterized. Solid SNEDDS was developed and characterized using optimized liquid SNEDDS followed by the development of
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M, Mounika, Kumar Desu Prasanna, and Vanitha K. "A Review on Self Nano Emulsifying Drug Delivery System." Trends in Pharmaceuticals and Nanotechnology (e-ISSN: 2582-4457) 2, no. 1 (2019): 12–23. https://doi.org/10.5281/zenodo.3579794.

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<em>A self-nano emulsifying drug delivery system (SNEDDS) is a scheme of drug delivery that utilizes a chemical rather than a mechanical method of Nano emulsion . That is, by an intrinsic property of the drug formulation. It utilizes the familiar ouzo impact shown by anethole in many anise-flavored liquors, rather than by unique blending and handling Nano emulsion s have significant potential for use in the delivery of drugs, and SNEDDS (including so-called &quot;U-type&quot; nano emulsions) is the best of those systems to date identified. SNEDDS are of particular value in increasing the absor
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Gande, Suresh, S. Srikanth Reddy, and Bhikshapathi D. V. R. N. "Enhancement of Nimodipine Solubility by Self-Nano-emulsifying Drug Delivery System." International Journal of Pharmaceutical Sciences and Nanotechnology 12, no. 5 (2019): 4648–56. http://dx.doi.org/10.37285/ijpsn.2019.12.5.5.

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Self-nanoemulsifying drug delivery system (SNEDDS) of Nimodipine was developed with the purpose of improving the bioavailability of the drug. Based on the results of Nimodipine solubility studies Peceol, Transcutol P and PEG 400 were optimized as oil, surfactant and co-surfactant for the formulation and Pseudo ternary plots was constructed by Chemix software. Fifteen formulations of Nimodipine SNEDDS prepared and analyzed for particle size, emulsification time, percentage drug release, percentage transmittance, in vitro drug dissolution studies and thermodynamic stability. The optimized Nimodi
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VERMA, ANUPAM, RAJESH ASIJA, and ANIL GOYAL. "SELF NANOEMULSIFYING DRUG DELIVERY SYSTEM: AN UPDATED REVIEW." Tropical Journal of Pharmaceutical and Life Sciences 9, no. 2 (2022): 11–20. https://doi.org/10.61280/tjpls.v9i2.81.

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Self- nano emulsifying drug delivery system (SNEDDS) is getting popularity for enhancing the solubility of hydrophobic drugs. SNEDDS are employed to solve issues regarding low bioavailability of poorly soluble and greatly permeable compounds. The SNEDDS are isotropic mixtures of solvents, co-solvents, surfactants and oil. The chief characteristic of SNEDDS is their capability to make acceptable Microemulsions or oil‐in‐water (o/w) emulsions with mild agitation. SNEDDS comprise a less content of lipid whereas greater amount of lipophobic surfactants and co-surfactants. Usually SNEDDS prepared a
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Vishakha, Vishwanath Doke, M. Khutle Nilesh, Sharma Maya, and Gupta Khemchand. "Self-Solidifying and Self-Nanoemulsifying Drug Delivery System of Itraconazole." Indian Journal of Science and Technology 16, no. 3 (2023): 190–203. https://doi.org/10.17485/IJST/v16i3.1940.

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ABSTRACT <strong>Objective:</strong>&nbsp;To improve solubility, dissolution, and permeability of BCS class II drug Itraconazole (ITZ) using a self solidifying self nano emulsifying drug delivery system (SNEDDS).&nbsp;<strong>Method:</strong>&nbsp;The solubility of ITZ was assessed in oils, surfactants, co-surfactants, and buffers. Surfactants, co-surfactants, and combination of surfactants (S-comb) were selected on the basis of emulsification efficacy test. The ability to solidify self emulsifying mixture was assessed and solid SNEDDSS was developed and optimised.&nbsp;<strong>Finding:</stron
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Chandran, Rajinikanth, and Kathiresan Krishnasamy. "Solubility Enhancement of Palbociclib Supersaturable Self-Nano Emulsifying Drug Delivery System by Central Composite Design." INTERNATIONAL JOURNAL OF PHARMACEUTICAL QUALITY ASSURANCE 15, no. 01 (2024): 169–77. http://dx.doi.org/10.25258/ijpqa.15.1.27.

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Nowadays, solid self-nano-emulsifying supersaturable drug delivery systems (S-SNEDDS) are being investigated to overcome the limitations of self-nano-emulsifying drug delivery systems (SNEDDS). The current study established S-SNEDDS for better drug dissolution and stability. S-SNEDDS were made with saturated solubility capryol® 90, labrosol®, and transcutol® HP. The composition was optimized using ternary phase diagrams. Palbociclib-SNEDDS created droplet size (Y1), polydispersity index (PDI) (Y2), and 15-minute drug release (Y3) responses using the central composite design (CCD) of response s
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Dash, Tapaswi Rani* Sharma Pankaj Sharma Sawati Sood Parul. "NOVEL SELF-NANOEMULSIFYING DRUG DELIVERY SYSTEMS (SNEDDS) FOR ORAL DELIVERY OF LIPOPHILIC DRUGS." INDO AMERICAN JOURNAL OF PHARMACEUTICAL RESEARCH 07, no. 01 (2017): 7361–68. https://doi.org/10.5281/zenodo.1006753.

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The self-nanoemulsifying drug delivery system (SNEDDS), is a promising Drug Delivery System which is well known for its prospective to improve the aqueous solubility and oral absorption of poorly water soluble drugs (Pouton, 2000). SNEDDS is an isotropic mixture comprising oil, surfactant, co-surfactant and drug that form oil in water emulsion in aqueous environment under placid agitation. It can readily disperse in the aqueous environment of the gastrointestinal tract to form a fine oil-in-water emulsion with a droplet size not exceeding 100 nm under mild agitation for improving the oral bioa
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., Pooja, Pankaj Kumar Sharma, and Viswanath Agrahari. "DESIGN AND EVALUATION OF SELF-NANO EMULSIFYING DRUG DELIVERY SYSTEMS OF ALVERINE FOR ENHANCEMENT OF SOLUBILITY." International Research Journal of Pharmacy 12, no. 7 (2021): 25–31. http://dx.doi.org/10.7897/2230-8407.1207153.

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Background: The aim of this study is to develop a liquid self-nano emulsifying drug delivery system for alverine (liquid-SNEDDS).Excipients in the alverine SNEDDS include Ethyl oleate as the oil phase, Tween 80 as a surfactant, and PEG600, Propylene glycol as a cosurfactant.The prepared eleven formulations of alverine SNEDDS were performed for emulsification time, percentage transmittance, particle size, drug release, in vitro dissolution and stability studies.The optimised alverine liquid SNEDDS formulation (D1) was studied for drug-excipient compatibility using infrared spectroscopy, as well
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Reddy, Sunitha M., and Sravani Baskarla. "A Review on Formulation and Development of Solid Self-Nano Emulsifying Drug Delivery Systems." International Journal of Pharmaceutical Sciences and Nanotechnology 14, no. 4 (2021): 5519–228. http://dx.doi.org/10.37285/ijpsn.2021.14.4.1.

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This article describes current strategies to enhance aqueous solubility and dissolution rate of poor soluble drugs. Most drugs in the market are lipophilic with low or poor water solubility. There are various methods to enhance solubility: co-solvency, particle size reduction, salt formation and Self Nanoemulsifying drug delivery systems, SEDDS is a novel approach to enhance solubility, dissolution rate and bioavailability of drugs. The study involves formulation and evaluation of solid self-Nano emulsifying drug delivery system (S-SNEDDS) to enhance aqueous solubility and dissolution rate. Or
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Fida, Saima, Aamir Jalil, Rukhshanda Habib, et al. "Development of mucus-penetrating iodine loaded self-emulsifying system for local vaginal delivery." PLOS ONE 17, no. 3 (2022): e0266296. http://dx.doi.org/10.1371/journal.pone.0266296.

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The major goal of this project was to formulate iodine-based self nano-emulsifying drug delivery system to provide improve antimicrobial activity and enhanced mucosal residence time via mucus penetration. Iodine SNEDDS (Self nano-emulsifying drug delivery system) with different concentration were formulated using castor oil as the oil phase, cremophor ethoxylated (CrEL) as a surfactant and after screening a number of vehicles, PEG 400 was employed as co-surfactant. Self-emulsification time, thermodynamic stability tests, robustness to dilution, percent transmittance, droplet size, and drug rel
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Conference papers on the topic "Selfnano emulsifying drug delivery system (SNEDDS)"

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Ermawati, Dian Eka, Roro Karina Pambudi, Vinda Aviwiandari, et al. "Developing formula of SNEDDS (self nano emulsifying drug delivery system) antihypertensive herbals “Hortus Medicus”." In THE 14TH JOINT CONFERENCE ON CHEMISTRY 2019. AIP Publishing, 2020. http://dx.doi.org/10.1063/5.0005630.

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Putri, Sri Ainaiyah Ariadi, Sunaryono Sunaryono, Nadiya Miftachul Chusna, Nasikhuddin Nasikhuddin, and Kormil Saputra. "Study of antioxidant of self nano emulsifying drug delivery system (SNEDDS)- Fe3O4/ginger extract ferrofluid." In THE 4TH MATERIALS RESEARCH SOCIETY OF INDONESIA (MRS-ID) MEETING. AIP Publishing, 2025. https://doi.org/10.1063/5.0240583.

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Syukri, Yandi, Bambang Hernawan Nugroho, and Muhammad Sirin. "Determination of andrographolide content in self nano emulsifying drug delivery system (SNEDDS) for in vitro diffusion study using validated HPLC." In PROCEEDINGS OF THE 3RD INTERNATIONAL SEMINAR ON METALLURGY AND MATERIALS (ISMM2019): Exploring New Innovation in Metallurgy and Materials. AIP Publishing, 2020. http://dx.doi.org/10.1063/5.0002446.

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Wahyuningsih, Iis, and Hani Pertiwi Khoirunnisa. "The Effects of SNEDDS (Self-Nano Emulsifying Drug Delivery System) Black Cumin Oil Seeds (Nigella sativa L) to The Histopatology of Lung Organs of The Sprague Dawley Rats That Induced by DMBA." In Proceedings of the 2019 Ahmad Dahlan International Conference Series on Pharmacy and Health Science (ADICS-PHS 2019). Atlantis Press, 2019. http://dx.doi.org/10.2991/adics-phs-19.2019.4.

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