Academic literature on the topic 'Sodium Citrate HPLC Determination'

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Journal articles on the topic "Sodium Citrate HPLC Determination"

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Abdrhman, Mahmoud Gamil, and Awad al-lkareem Hamad Mohamed. "Development and validation of stability indicating method for determination of sodium citrate in pediatric cough syrup." World Journal of Advanced Research and Reviews 8, no. 2 (2020): 213–23. https://doi.org/10.5281/zenodo.4318624.

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Sodium Citrate is widely used in analytical and food processes. It is used in various medical applications as anticoagulant in blood transfusion process and bladder washout. It is used in cough preparation as mucolytic. There are many methods for determination of Sodium Citrate in different preparations. Some of which use spectrophotometric methods, others used HPLC methods. The USP method uses titration and determining the end point potentionometrically. Many arguments take place between the Drug Regulatory Affairs and manufacturers regarding the appearance of the colour at the end point. The
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Williams, Robert H., Jack A. Maggiore, Robert D. Reynolds, and Cathy M. Helgason. "Novel Approach for the Determination of the Redox Status of Homocysteine and Other Aminothiols in Plasma from Healthy Subjects and Patients with Ischemic Stroke." Clinical Chemistry 47, no. 6 (2001): 1031–39. http://dx.doi.org/10.1093/clinchem/47.6.1031.

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Abstract Background: Plasma “redox” status can be assessed by measurements of reduced (r)-, free (f)-, oxidized (ox)-, and protein-bound (b)-homocysteine (Hcy) plus the related aminothiols cysteine, cysteinylglycine (CysGly), and glutathione (GSH), but sample collection has been complex. The redox status has not been determined in ischemic stroke patients and may provide increased understanding of its role in pathogenesis. We wished to examine the feasibility of this measurement in samples collected in readily available acidic sodium citrate. Methods: We measured aminothiols and their stabilit
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Abdrhman Mahmoud Gamil and Mohamed Awad al-lkareem Hamad. "Development and validation of stability indicating method for determination of sodium citrate in pediatric cough syrup." World Journal of Advanced Research and Reviews 8, no. 2 (2020): 213–23. http://dx.doi.org/10.30574/wjarr.2020.5.2.0427.

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Sodium Citrate is widely used in analytical and food processes. It is used in various medical applications as anticoagulant in blood transfusion process and bladder washout. It is used in cough preparation as mucolytic. There are many methods for determination of Sodium Citrate in different preparations. Some of which use spectrophotometric methods, others used HPLC methods. The USP method uses titration and determining the end point potentionometrically. Many arguments take place between the Drug Regulatory Affairs and manufacturers regarding the appearance of the colour at the end point. The
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Abdrhman Mahmoud Gamil and Mohamed Awad al-lkareem Hamad. "Development and validation of stability indicating method for determination of sodium citrate in pediatric cough syrup." World Journal of Advanced Research and Reviews 8, no. 2 (2020): 213–23. http://dx.doi.org/10.30574/wjarr.2020.8.2.0427.

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Abstract:
Sodium Citrate is widely used in analytical and food processes. It is used in various medical applications as anticoagulant in blood transfusion process and bladder washout. It is used in cough preparation as mucolytic. There are many methods for determination of Sodium Citrate in different preparations. Some of which use spectrophotometric methods, others used HPLC methods. The USP method uses titration and determining the end point potentionometrically. Many arguments take place between the Drug Regulatory Affairs and manufacturers regarding the appearance of the colour at the end point. The
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El-Fatatry, Hamed M., Mokhtar M. Mabrouk, Ismail I. Hewala, and Ehab H. Emam. "Stability-indicating HPLC–DAD methods for determination of two binary mixtures: Rabeprazole sodium–mosapride citrate and rabeprazole sodium–itopride hydrochloride." Journal of Pharmaceutical Analysis 4, no. 4 (2014): 258–69. http://dx.doi.org/10.1016/j.jpha.2013.09.009.

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Khedr, Alaa, Mohamed Moustafa, Ashraf B. Abdel-Naim, Abdulrahman Alahdal, and Hisham Mosli. "High-Performance Liquid Chromatographic Method for Determination of Phenytoin in Rabbits Receiving Sildenafil." Analytical Chemistry Insights 3 (January 2008): ACI.S658. http://dx.doi.org/10.4137/aci.s658.

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A validated high-performance liquid chromatographic (HPLC) method for determination of phenytoin (PHN), para-hydroxy metabolite of phenytoin (POH) and sildenafil (SIL) in rabbit plasma is described. The method is based on extraction on Sep-Pak C18 solid support using ethyl acetate and ether as eluents and monitoring at 220 nm. The extracted samples were analyzed by HPLC using Agilent Zorbax Extended C18 column (150 mm x 4.6 mm internal diameter) and isocratic elution with a mobile phase consist of 29% acetonitrile and 71% sodium acetate solution (0.02 M, pH 4.6). The method was fully validated
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Xu, Quanyun A., Lawrence A. Trissel, and Juan F. Martinez. "Drug Stability: Rapid Loss of Fentanyl Citrate Admixed with Fluorouracil in Polyvinyl Chloride Containers." Annals of Pharmacotherapy 31, no. 3 (1997): 297–302. http://dx.doi.org/10.1177/106002809703100305.

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Objective To study the physical compatibility and chemical stability of fluorouracil 1 and 16 mg/mL with fentanyl citrate 12.5 μg/mL in dextrose 5% and in sodium chloride 0.9% injection. Design Test solutions of the drugs in dextrose 5% injection and in sodium chloride 0.9% injection were prepared in triplicate and stored at −20, 4, 23, and 32 °C. Samples were removed immediately and at various times over 7 days and stored at −70 °C until analyzed. Physical compatibility was assessed visually and by measuring turbidity with a color-correcting turbidimeter; particle content was measured with a
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Wongchang, Thamrong, Markus Winterberg, Joel Tarning, Natthida Sriboonvorakul, Sant Muangnoicharoen, and Daniel Blessborn. "Determination of ceftriaxone in human plasma using liquid chromatography–tandem mass spectrometry." Wellcome Open Research 4 (May 31, 2022): 47. http://dx.doi.org/10.12688/wellcomeopenres.15141.3.

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Ceftriaxone is a cephalosporin antibiotic drug used as first-line treatment for a number of bacterial diseases. Ceftriaxone belongs to the third generation of cephalosporin and is available as an intramuscular or intravenous injection. Previously published pharmacokinetic studies have used high-performance liquid chromatography coupled with ultraviolet detection (HPLC-UV) for the quantification of ceftriaxone. This study aimed to develop and validate a bioanalytical method for the quantification of ceftriaxone in human plasma using liquid chromatography followed by tandem mass spectrometry (LC
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Wongchang, Thamrong, Markus Winterberg, Joel Tarning, Natthida Sriboonvorakul, Sant Muangnoicharoen, and Daniel Blessborn. "Determination of ceftriaxone in human plasma using liquid chromatography–tandem mass spectrometry." Wellcome Open Research 4 (September 3, 2021): 47. http://dx.doi.org/10.12688/wellcomeopenres.15141.2.

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Ceftriaxone is a cephalosporin antibiotic drug used as first-line treatment for a number of bacterial diseases. Ceftriaxone belongs to the third generation of antibiotics and is available as an intramuscular or intravenous injection. Previously published pharmacokinetic studies have used high-performance liquid chromatography coupled with ultraviolet detection (HPLC-UV) for the quantification of ceftriaxone. This study aimed to develop and validate a bioanalytical method for the quantification of ceftriaxone in human plasma using liquid chromatography followed by tandem mass spectrometry (LC-M
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Grechina, Marina S., Alena V. Suslova, and Viktoriya V. Belitskaya. "On the issue of analytical control of quinone derivatives in habitats." Toxicological Review 29, no. 4 (2021): 45–50. http://dx.doi.org/10.36946/0869-7922-2021-29-4-45-50.

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Introduction. In the direction of normative and methodological assurance of the safety of environmental objects and imported food products, analytical approaches to the determination of a fungicide of the quinone class - dithianone in the air and citrus fruits were optimized. Materials and methods. Measurements were performed by tandem liquid mass spectrometry with a triple quadrupole mass detector (HPLC-MS/MS) in multiple reaction monitoring (MRM) mode using electrostatic spray as the ionization source. The substance from the air was concentrated on Tenax TA sorption tubes based on a porous p
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Dissertations / Theses on the topic "Sodium Citrate HPLC Determination"

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Krishnakumar, Megha. "Physicochemical compatibility and stability of 4% sodium citrate and ethanol when stored in silicone coated and non-silicone coated glass containers." University of Toledo Health Science Campus / OhioLINK, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=mco1588869684016374.

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Fakir, Rehana Ebrahim. "Determination of measurement uncertainty in the analysis of sodium lactate using the HPLC method." Thesis, 2009. http://hdl.handle.net/10539/6942.

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Book chapters on the topic "Sodium Citrate HPLC Determination"

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Veress, I., N. Ilinca, and M. T. Paraschivescu. "Effect of sodium citrate on sperm motility and citological determination for Buffalo semen processing." In Book of Abstracts of the 52nd Annual Meeting of the European Association for Animal Production. Brill | Wageningen Academic, 2001. https://doi.org/10.1163/9789004683648_134.

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Ranjith, K., D. Rama Sekhara Reddy, and TEGK Murthy. "Development and Validation of Stability Indicating Related Substances Method for Montelukast Sodium and Levocetirizine Dihydrochloride Combined Tablets by RP-HPLC." In Current Trends in Drug Discovery, Development and Delivery (CTD4-2022). Royal Society of Chemistry, 2023. http://dx.doi.org/10.1039/9781837671090-00304.

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In this paper authors presented the development and validation of RP-HPLC method for determination of related substances present in Montelukast sodium and Levocetirizine dihydrochloride combined tablets. Chromatographic separation was achieved on Hypersil ODS (150 x 4.6 mm),5 µ column with flow rate 1 mL/min, detection wavelength 238 nm, injection volume 10 µL, column temperature 40°C and run time 75 mins. Gradient programming was used with mobile phase-A (MP-A)-50mM acetate buffer pH 5.5 and mobile phase-B(MP-B)-methanol: MP-A (90:10 %v/v). Developed method was validated as per ICH Q2(R1) gui
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"Development of a method for the quantitative determination of kanamycin in the active pharmaceutical substance of insulin Degludec." In Book of Abstracts - RAD 2025 Conference. RAD Centre, Niš, Serbia, 2025. https://doi.org/10.21175/rad.abstr.book.2025.29.1.

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Introduction Kanamycin sulfate is an antibiotic used for cell selection. Although kanamycin is eliminated during the preparation of raw materials, there is a risk that trace amounts may remain and carry over into the final product. Residual kanamycin could trigger allergic reactions in consumers. Therefore, it is essential to monitor the obtained active pharmaceutical ingredient (API) for the presence of residual kanamycin. This experiment aimed to determine optimal conditions for obtaining reproducible results on any high-performance liquid chromatography (HPLC) system, specifically ensuring
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Conference papers on the topic "Sodium Citrate HPLC Determination"

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Schatz, Tim, Abby Beltrame, Sarah Howard, and Mark Smith. "Modification of the ASTM Platelet and Leukocyte Assay: Use of an Alternative and Clinically Relevant Anticoagulant — An In-Vitro Hemocompatibility Assessment of Blood Contacting Medical Devices." In 2017 Design of Medical Devices Conference. American Society of Mechanical Engineers, 2017. http://dx.doi.org/10.1115/dmd2017-3345.

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The purpose of this test method is to assist in the determination of the thrombogenic potential of medical materials exposed to human whole blood. By evaluating surface-induced activation, platelet adherence to a material, and platelet and leukocyte depletion from blood, a material’s potential for thrombus formation can be assessed. If a significant decrease in platelets and/or leukocytes is observed in whole blood when compared to a blank control, the tested material has the potential to induce an in-vivo thrombogenic response. The present standard for the testing of platelet and leukocyte re
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Carvalho, Renato, Alan Sobrinho, Ana Bergamo, and Simone Fernandes. "Development of an HPLC method for the determination of sorbitol and sodium glutamate in the thermostabilizer employed in yellow-fever vaccine." In International Symposium on Immunobiological. Instituto de Tecnologia em Imunobiológicos, 2024. http://dx.doi.org/10.35259/isi.biomang.2024_63961.

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Nenadović, Milena, Katja Kržišnik, Polonca Trebše, and Mojca Bavcon Kralj. "Effect of Time, pH, Alcohol and Sugar Content on Nicotine Re-lease from Pouches Available on Slovene Market." In Socratic lectures 10. University of Lubljana Press, 2024. http://dx.doi.org/10.55295/psl.2024.ii7.

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Abstract: Tobacco-free nicotine pouches, first introduced in Sweden, are made as a less hazardous product for cigarette consumers. Instead of tobacco leaves, they consist of nicotine-containing powder and other ingredients such as water, salts, natural aromatic oils and others, that will boost the flavor and effect and make it last longer. This research aimed to investigate the extraction efficiency of nicotine from poaches of different brands. The effects of alcohol and sugars present in saliva at different pHs and consumption times were investigated as well. We optimized a High performance l
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Khazaradze, Natia, and Khatuna Omiadze. "Study of Dmanisi Mineral Water." In Multidisciplinary International Scientific Conference: „Sustainable Development: Modern Trends and Challenges“. Kutaisi University, 2024. https://doi.org/10.52244/c.2024.11.31.

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The object of study is the mineral water "Dmanisi" in the municipality of Dmanisi. Although water has been used for centuries to treat kidney diseases, it was studied by us for the first time. Sampling water in different seasons were studied by chemical, microbiological and physico-chemical methods: Study of chemical composition: (determination of pH, hardness, Na+ and K+ by flame emission spectrometry (ISO 9964-3:2010); Sstudy of anions and cations by ion-exchange chromatography: ISO 9964-3:2010, ISO 10304-1:2007 , ISO 10523:2010); Determination of heavy metals: plasma-emission and plasma-emi
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Sugimori, Daisuke, Kiyoto Kajiyama, Shunsuke Kawashima, and Yuho Matsumoto. "Phosphatidylglycerol-specific Phospholipase C from Amycolatopsis Sp. NT115: Biochemical Characterization and Heterologous Expression." In 2022 AOCS Annual Meeting & Expo. American Oil Chemists' Society (AOCS), 2022. http://dx.doi.org/10.21748/fmmj5845.

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In recent years, phosphatidylglycerol (PG) has been attracting attention in the field of cell physiology such as photosynthesis and germ cells, or clinical diagnosis. Most of phospholipids containing PG are analyzed using HPLC and LC-MS; however, it has been desired to develop an enzymatic assay method for determination of PG concentration in a simple, easy, and high-through put.In our presentation, biochemical characterization of a PG-specific phospholipase C (PG-PLC) from Amycolatopsis sp. NT115 will be reported. PG-PLC (molecular mass, 55 kDa) showed maximal activity at pH 6.0 and 55°C. PG-
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