Relevant bibliographies by topics / Soluble epoxide hydrolase subdomains

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers

Academic literature on the topic 'Soluble epoxide hydrolase subdomains'

Author: Grafiati
Published: 18 May 2024
Last updated: 31 July 2025

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the lists of relevant articles, books, theses, conference reports, and other scholarly sources on the topic 'Soluble epoxide hydrolase subdomains.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Journal articles on the topic "Soluble epoxide hydrolase subdomains"

1

Gupta, Nandita C., Catherine M. Davis, Jonathan W. Nelson, Jennifer M. Young, and Nabil J. Alkayed. "Soluble Epoxide Hydrolase." Arteriosclerosis, Thrombosis, and Vascular Biology 32, no. 8 (2012): 1936–42. http://dx.doi.org/10.1161/atvbaha.112.251520.

Full text
APA, Harvard, Vancouver, ISO, and other styles
2

Sontakke, Pooja M., Suraj G. Malpani, Pooja R. Tange, MD Rayees Ahmad, and Vishweshwar M. Dharashive. "Soluble Epoxide Hydrolase." Asian Journal of Pharmaceutical Research and Development 12, no. 2 (2024): 87–95. http://dx.doi.org/10.22270/ajprd.v12i2.1369.

Full text
Abstract:
Epoxyeicosatrienoic acids (EETs) have numerous cardiovascular benefits, including vasodilation, anti-inflammatory actions, and anti-migratory effects on vascular smooth muscle cells. However, sEH, an enzyme that breaks down EETs into diols, limits these benefits. The development of sEH inhibitors (sEHIs), particularly those based on 1,3-disubstituted urea, has shown promise in enhancing the therapeutic properties of EETs. These inhibitors are antihypertensive and anti-inflammatory and can protect the heart, brain, and kidneys from damage. While there are still challenges to overcome, such as i
APA, Harvard, Vancouver, ISO, and other styles
3

Yu, Zhigang, Benjamin B. Davis, Christophe Morisseau, et al. "Vascular localization of soluble epoxide hydrolase in the human kidney." American Journal of Physiology-Renal Physiology 286, no. 4 (2004): F720—F726. http://dx.doi.org/10.1152/ajprenal.00165.2003.

Full text
Abstract:
Epoxyeicosatrienoic acids are cytochrome P-450 metabolites of arachidonic acid with multiple biological functions, including the regulation of vascular tone, renal tubular transport, cellular proliferation, and inflammation. Epoxyeicosatrienoic acids are converted by soluble epoxide hydrolase into the corresponding dihydroxyeicosatrienoic acids, and epoxyeicosatrienoic acid hydration is regarded as one mechanism whereby their biological effects are eliminated. Previous animal studies indicate that soluble epoxide hydrolase plays an important role in the regulation of renal eicosanoid levels an
APA, Harvard, Vancouver, ISO, and other styles
4

Ma, Liang, Hailing Zhao, Meijie Yu, et al. "Association of Epoxide Hydrolase 2 Gene Arg287Gln with the Risk for Primary Hypertension in Chinese." International Journal of Hypertension 2020 (February 28, 2020): 1–7. http://dx.doi.org/10.1155/2020/2351547.

Full text
Abstract:
Background. Epoxide hydrolase 2 (EPHX2) gene coding for soluble epoxide hydrolase is a potential candidate in the pathogenesis of hypertension. Objectives. We aimed to assess the association of a missense mutation, R287Q, in EPHX2 gene with primary hypertension risk and examine its association with enzyme activity of soluble epoxide hydrolase. Methods. This study involved 782 patients with primary hypertension and 458 healthy controls. Genotyping was done using TaqMan technique. Activity of soluble epoxide hydrolase fusion proteins was evaluated by the conversion of 11,12-EET to corresponding
APA, Harvard, Vancouver, ISO, and other styles
5

Borhan, Babak, A. Daniel Jones, Franck Pinot, David F. Grant, Mark J. Kurth, and Bruce D. Hammock. "Mechanism of Soluble Epoxide Hydrolase." Journal of Biological Chemistry 270, no. 45 (1995): 26923–30. http://dx.doi.org/10.1074/jbc.270.45.26923.

Full text
APA, Harvard, Vancouver, ISO, and other styles
6

Wang, Yi-Xin Jim, Arzu Ulu, Le-Ning Zhang, and Bruce Hammock. "Soluble Epoxide Hydrolase in Atherosclerosis." Current Atherosclerosis Reports 12, no. 3 (2010): 174–83. http://dx.doi.org/10.1007/s11883-010-0108-5.

Full text
APA, Harvard, Vancouver, ISO, and other styles
7

He, Xin, Wen-Yu Zhao, Bo Shao, et al. "Natural soluble epoxide hydrolase inhibitors from Inula helenium and their interactions with soluble epoxide hydrolase." International Journal of Biological Macromolecules 158 (September 2020): 1362–68. http://dx.doi.org/10.1016/j.ijbiomac.2020.04.227.

Full text
APA, Harvard, Vancouver, ISO, and other styles
8

Anita, Natasha Z., and Walter Swardfager. "Soluble Epoxide Hydrolase and Diabetes Complications." International Journal of Molecular Sciences 23, no. 11 (2022): 6232. http://dx.doi.org/10.3390/ijms23116232.

Full text
Abstract:
Type 2 diabetes mellitus (T2DM) can result in microvascular complications such as neuropathy, retinopathy, nephropathy, and cerebral small vessel disease, and contribute to macrovascular complications, such as heart failure, peripheral arterial disease, and large vessel stroke. T2DM also increases the risks of depression and dementia for reasons that remain largely unclear. Perturbations in the cytochrome P450-soluble epoxide hydrolase (CYP-sEH) pathway have been implicated in each of these diabetes complications. Here we review evidence from the clinical and animal literature suggesting the i
APA, Harvard, Vancouver, ISO, and other styles
9

Bellevik, Stefan, Jiaming Zhang, and Johan Meijer. "Brassica napus soluble epoxide hydrolase (BNSEH1)." European Journal of Biochemistry 269, no. 21 (2002): 5295–302. http://dx.doi.org/10.1046/j.1432-1033.2002.03247.x.

Full text
APA, Harvard, Vancouver, ISO, and other styles
10

Przybyla-Zawislak, Beata D., Punit K. Srivastava, Johana Vázquez-Matías, et al. "Polymorphisms in Human Soluble Epoxide Hydrolase." Molecular Pharmacology 64, no. 2 (2003): 482–90. http://dx.doi.org/10.1124/mol.64.2.482.

Full text
APA, Harvard, Vancouver, ISO, and other styles
More sources

Dissertations / Theses on the topic "Soluble epoxide hydrolase subdomains"

1

Varennes, Olivier. "Le rôle de l'Epoxyde hydrolase soluble (sEH) dans la physiopathologie des calcifications vasculaires." Electronic Thesis or Diss., Amiens, 2018. http://www.theses.fr/2018AMIE0046.

Full text
Abstract:
L'Epoxide Hydrolase soluble (sEH) est une enzyme exprimée dans les vaisseaux. Elle possède un domaine hydrolase à l'extrémité COOH-term (sEH-H) qui métabolise des facteurs vasodilatateurs et anti-inflammatoires comme les acides époxyeicosatriénoïques (EETs). Elle possède également un domaine phosphatase à l'extrémité NH2-term (sEH-P) dont le rôle biologique n'est pas totalement élucidé. Afin de comprendre le rôle de sEH-H et sEH-P dans la calcification vasculaire, des anneaux aortiques de rats et des cellules musculaires lisses vasculaires humaines (CMLVh) ont été exposés à des conditions proc
APA, Harvard, Vancouver, ISO, and other styles
2

Sellers, Kathleen Walworth. "Role of brain soluble epoxide hydrolase in cardiovascular function." [Gainesville, Fla.] : University of Florida, 2004. http://purl.fcla.edu/fcla/etd/UFE0008356.

Full text
Abstract:
Thesis (Ph.D.)--University of Florida, 2004.<br>Typescript. Title from title page of source document. Document formatted into pages; contains 156 pages. Includes Vita. Includes bibliographical references.
APA, Harvard, Vancouver, ISO, and other styles
3

Davis, Benjamin Boyce. "Novel treatments for atherosclerosis with inhibitors of soluble epoxide hydrolase /." For electronic version search Digital dissertations database. Restricted to UC campuses. Access is free to UC campus dissertations, 2005. http://uclibs.org/PID/11984.

Full text
APA, Harvard, Vancouver, ISO, and other styles
4

Sandberg, Martin. "Mammalian soluble epoxide hydrolase : studies on gene structure and expression /." Uppsala : Swedish Univ. of Agricultural Sciences (Sveriges lantbruksuniv.), 2000. http://epsilon.slu.se/avh/2000/91-576-5747-5.pdf.

Full text
APA, Harvard, Vancouver, ISO, and other styles
5

Varennes, Olivier. "Le rôle de l'Epoxyde hydrolase soluble (sEH) dans la physiopathologie des calcifications vasculaires." Thesis, Amiens, 2018. http://www.theses.fr/2018AMIE0046/document.

Full text
Abstract:
L'Epoxide Hydrolase soluble (sEH) est une enzyme exprimée dans les vaisseaux. Elle possède un domaine hydrolase à l'extrémité COOH-term (sEH-H) qui métabolise des facteurs vasodilatateurs et anti-inflammatoires comme les acides époxyeicosatriénoïques (EETs). Elle possède également un domaine phosphatase à l'extrémité NH2-term (sEH-P) dont le rôle biologique n'est pas totalement élucidé. Afin de comprendre le rôle de sEH-H et sEH-P dans la calcification vasculaire, des anneaux aortiques de rats et des cellules musculaires lisses vasculaires humaines (CMLVh) ont été exposés à des conditions proc
APA, Harvard, Vancouver, ISO, and other styles
6

Newman, John William. "Novel tools for the investigation of the endogenous role of soluble epoxide hydrolase /." For electronic version search Digital dissertations database. Restricted to UC campuses. Access is free to UC campus dissertations, 2002. http://uclibs.org/PID/11984.

Full text
APA, Harvard, Vancouver, ISO, and other styles
7

Codony, Gisbert Sandra. "From the design to the in vivo evaluation of novel soluble epoxide hydrolase inhibitors." Doctoral thesis, Universitat de Barcelona, 2020. http://hdl.handle.net/10803/671480.

Full text
Abstract:
Epoxieicosatrienoic acids acids (EETs) are endogenous chemical mediators derived from arachidonic acid that show anti-inflammatory, antihypertensive, analgesic, angiogenic and antiatherosclerotic effects. Soluble epoxide hydrolase (sEH) converts EETs to their corresponding dihydroxyeicosatrienoic acids, whereby the biological effects of EETs are diminished, eliminated, or altered. Therefore, it has been proposed that inhibition of sEH may have therapeutic effects in various inflammatory and pain-related diseases. A number of very potent sEH inhibitors (sEHIs) have been developed, several of th
APA, Harvard, Vancouver, ISO, and other styles
8

Duflot, Thomas. "Rôle de l'époxyde hydrolase soluble dans les maladies cardiovasculaires." Thesis, Normandie, 2018. http://www.theses.fr/2018NORMR037.

Full text
Abstract:
L’époxyde hydrolase soluble (sEH) est une enzyme ubiquitaire, bifonctionnelle, codée par le gène EPHX2. La partie hydrolase (sEH-H) est responsable de la dégradation de facteurs endothéliaux vasodilatateurs, les acides époxyeicosatriénoïques (EETs), alors que la partie phosphatase (sEH-P) est impliquée dans le métabolisme des acides lysophosphatidiques (LPAs).L’objectif de ce travail a été de développer des outils méthodologiques permettant d'évaluer le rôle de la sEH dans la physiopathologie des maladies cardiovasculaires.Nous avons développé une méthode de quantification par CLHP-MS² des EET
APA, Harvard, Vancouver, ISO, and other styles
9

Feugray, Guillaume. "Evaluatiοn translatiοnnelle de l’activité phοsphatase de l’épοxyde hydrοlase sοluble au cοurs des maladies cardiοmétabοliques". Electronic Thesis or Diss., Normandie, 2024. http://www.theses.fr/2024NORMR101.

Full text
Abstract:
L’époxyde hydrolase soluble (sEH) est une enzyme bifonctionnelle codée par le gène EPHX2 et qui présente une activité hydrolase (sEH-H) sur son domaine C-terminal et une activité phosphatase (sEH-P) sur son domaine N-terminal. La sEH-H est impliquée dans le métabolisme des acides gras époxydés et plus particulièrement des acides époxyeicosatriénoïques (EETs). Ils présentent des effets vasodilatateurs, pro-angiogéniques et anti-inflammatoires. Ils sont métabolisés en dérivés diols biologiquement moins actifs par la sEH-H. Actuellement, des inhibiteurs pharmacologiques sont en cours d’investigat
APA, Harvard, Vancouver, ISO, and other styles
10

Leuillier, Matthieu. "Rôle de l'activité phosphatase de l'époxyde hydrolase soluble dans la régulation de l'homéostasie métabolique et cardiovasculaire. In vivo inactivation of the phosphatase activity of soluble epoxide hydrolase potentiates brown adispose thermogenesis and protects against cardiovascular damage and remodeling Discovery of the first in vivo active inhibitors of the soluble epoxide hydrolase phosphatase domain Altered bioavailability of epoxyeicosatrienoic acids is associated with conduit artery endothelial dysfunction in type 2 diabetic patients." Thesis, Normandie, 2019. http://www.theses.fr/2019NORMR150.

Full text
Abstract:
Près de 40 ans après sa découverte initiale en 1972, il a été montré en 2003 que l'époxyde hydrolase soluble (sEH), codée par le gène EPHX2, est une protéine bifonctionnelle qui présente non seulement une activité époxyde hydrolase au niveau de sa partie C-terminale mais également une activité lipidophosphatase sur son domaine N-terminal. En effet, au niveau de sa partie C-terminale, l’activité hydrolase métabolise des époxydes d'acides gras polyinsaturés. Notamment, elle transforme les acides époxyeicosatriénoïques, facteurs vasodilatateurs et anti-inflammatoires biologiquement actifs générés
APA, Harvard, Vancouver, ISO, and other styles
More sources

Books on the topic "Soluble epoxide hydrolase subdomains"

1

Imig, John D., and Christophe Morisseau, eds. Clinical Paths for Soluble Epoxide Hydrolase Inhibitors. Frontiers Media SA, 2020. http://dx.doi.org/10.3389/978-2-88966-161-9.

Full text
APA, Harvard, Vancouver, ISO, and other styles

Book chapters on the topic "Soluble epoxide hydrolase subdomains"

1

Singh, Nalin, and Bruce D. Hammock. "Soluble Epoxide Hydrolase." In Encyclopedia of Molecular Pharmacology. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-21573-6_10020-1.

Full text
APA, Harvard, Vancouver, ISO, and other styles
2

Singh, Nalin, and Bruce D. Hammock. "Soluble Epoxide Hydrolase." In Encyclopedia of Molecular Pharmacology. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-57401-7_10020.

Full text
APA, Harvard, Vancouver, ISO, and other styles
3

Nelson, Jonathan W., and Nabil J. Alkayed. "Soluble Epoxide Hydrolase as a Stroke Target." In Translational Stroke Research. Springer New York, 2012. http://dx.doi.org/10.1007/978-1-4419-9530-8_13.

Full text
APA, Harvard, Vancouver, ISO, and other styles
4

"Soluble epoxide hydrolase." In Class 3 Hydrolases. Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-540-85703-7_37.

Full text
APA, Harvard, Vancouver, ISO, and other styles
5

Zhao, Ming-Ming, Jian-Jun Yang, and Kenji Hashimoto. "Soluble epoxide hydrolase: Mechanisms and therapeutic potential in psychiatric and neurological disorders." In Advances in Pharmacology. Elsevier, 2024. http://dx.doi.org/10.1016/bs.apha.2024.10.007.

Full text
APA, Harvard, Vancouver, ISO, and other styles
6

Nayeem, Mohammed A., Werner J. Geldenhuys, and Ahmad Hanif. "Role of cytochrome P450-epoxygenase and soluble epoxide hydrolase in the regulation of vascular response." In Advances in Pharmacology. Elsevier, 2023. http://dx.doi.org/10.1016/bs.apha.2022.12.003.

Full text
APA, Harvard, Vancouver, ISO, and other styles
7

Kandasamy, Ram, and Stevan Pecic. "Treatment of pain with dual fatty acid amide hydrolase (FAAH) enzyme and human soluble epoxide hydrolase (sEH) enzyme inhibitors: Interlinking the endocannabinoid system." In Neurobiology and Physiology of the Endocannabinoid System. Elsevier, 2023. http://dx.doi.org/10.1016/b978-0-323-90877-1.00039-5.

Full text
APA, Harvard, Vancouver, ISO, and other styles
8

Hung, Shao-Wen, Chia-Chi Chen, Hsiao-Yun Chen, Ying-Ching Hung, Ping-Min Huang, and Chia-Yu Lin. "The Role of Microglia in Neuroinflammation." In Epilepsy - Seizures Without Triggers [Working Title]. IntechOpen, 2022. http://dx.doi.org/10.5772/intechopen.105865.

Full text
Abstract:
Microglia typically exist in a resting state of a mature brain and monitors the brain environment. In response to brain injuries or immunological stimuli, however, microglia are readily activated. In their activated state, they can serve diverse beneficial functions essential for enhancing neuron survival through the release of trophic and anti-inflammatory factors. Under certain circumstances, such as sustained epilepsy, however, microglia become overactivated and can induce significant and highly detrimental neurotoxic effects by the excessive production of a large array of cytotoxic factors
APA, Harvard, Vancouver, ISO, and other styles

Conference papers on the topic "Soluble epoxide hydrolase subdomains"

1

Lazaar, Aili, Lucy Yang, Jon Robertson, et al. "Safety and pharmacology of a soluble epoxide hydrolase inhibitor." In Annual Congress 2015. European Respiratory Society, 2015. http://dx.doi.org/10.1183/13993003.congress-2015.pa2120.

Full text
APA, Harvard, Vancouver, ISO, and other styles
2

Yang, Jun, Jennifer Bratt, Lisa Franzi, et al. "Soluble Epoxide Hydrolase Inhibitor Attenuates The Ovalbumin-Induced Murine Asthmatic Symptoms." In American Thoracic Society 2012 International Conference, May 18-23, 2012 • San Francisco, California. American Thoracic Society, 2012. http://dx.doi.org/10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a1425.

Full text
APA, Harvard, Vancouver, ISO, and other styles
3

Achanta, S., A. Marcus, A. Caceres, and S. E. Jordt. "Soluble Epoxide Hydrolase Inhibitors and ACE Inhibitors Ameliorate Phosgene Inhalation Injuries." In American Thoracic Society 2023 International Conference, May 19-24, 2023 - Washington, DC. American Thoracic Society, 2023. http://dx.doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a1171.

Full text
APA, Harvard, Vancouver, ISO, and other styles
4

Davis, Benjamin B., Jun-Yan Liu, Daniel J. Tancredi, Scott I. Simon, Bruce D. Hammock, and Kent E. Pinkerton. "Anti-inflammatory Effects Of Soluble Epoxide Hydrolase Inhibition Are Independent Of Leukocyte Recruitment." In American Thoracic Society 2010 International Conference, May 14-19, 2010 • New Orleans. American Thoracic Society, 2010. http://dx.doi.org/10.1164/ajrccm-conference.2010.181.1_meetingabstracts.a5751.

Full text
APA, Harvard, Vancouver, ISO, and other styles
5

Liu, Jun-Yan, Ai-Zhi Lin, Xian Fu, Jiang Qing, and Bruce Hammock. "Inhibition of soluble epoxide hydrolase attenuates high-sucrose diet-mediated gut barrier dysfunction." In ASPET 2024 Annual Meeting Abstract. American Society for Pharmacology and Experimental Therapeutics, 2024. http://dx.doi.org/10.1124/jpet.556.979490.

Full text
APA, Harvard, Vancouver, ISO, and other styles
6

Kandasamy, Ram, Tiffany Chacon, Christopher Chin, and Stevan Pecic. "Simultaneous Inhibition of Soluble Epoxide Hydrolase and Fatty Acid Amide Hydrolase Prevents Nitroglycerin-induced Hypersensitivity in Female Rats." In ASPET 2024 Annual Meeting Abstract. American Society for Pharmacology and Experimental Therapeutics, 2024. http://dx.doi.org/10.1124/jpet.476.907640.

Full text
APA, Harvard, Vancouver, ISO, and other styles
7

Pecic, Stevan, Ram Kandasamy, and Jeannes Angelia. "Multitarget-Directed Ligands with Soluble Epoxide Hydrolase and Fatty Acid Amide Hydrolase Inhibitory Activities for Treatment of Chronic Pain." In ASPET 2024 Annual Meeting Abstract. American Society for Pharmacology and Experimental Therapeutics, 2024. http://dx.doi.org/10.1124/jpet.474.878670.

Full text
APA, Harvard, Vancouver, ISO, and other styles
8

Liao, Jie, Stephanie D. Norwood, Yeon Tae Chung, Haonan Li, Bruce D. Hammock, and Guang-Yu Yang. "Abstract 5702: Soluble epoxide hydrolase: unique biomarker and chemopreventive target of chronic colitis-induced carcinogenesis." In Proceedings: AACR 101st Annual Meeting 2010‐‐ Apr 17‐21, 2010; Washington, DC. American Association for Cancer Research, 2010. http://dx.doi.org/10.1158/1538-7445.am10-5702.

Full text
APA, Harvard, Vancouver, ISO, and other styles
9

Yang, Jun, Lisa Franzi, Hua Dong, et al. "Soluble Epoxide Hydrolase Is A Novel Therapeutic Target In Asthma By Modulating The Inflammatory Response." In American Thoracic Society 2010 International Conference, May 14-19, 2010 • New Orleans. American Thoracic Society, 2010. http://dx.doi.org/10.1164/ajrccm-conference.2010.181.1_meetingabstracts.a4241.

Full text
APA, Harvard, Vancouver, ISO, and other styles
10

Yuan, Cassandra, Ashley Murray, Christopher Chin, et al. "Effects of Simultaneous Inhibition of Fatty Acid Amide Hydrolase and Soluble Epoxide Hydrolase on Acute and Persistent Pain in Male Rats." In ASPET 2023 Annual Meeting Abstracts. American Society for Pharmacology and Experimental Therapeutics, 2023. http://dx.doi.org/10.1124/jpet.122.186070.

Full text
APA, Harvard, Vancouver, ISO, and other styles
You might also be interested in the extended bibliographies on the topic 'Soluble epoxide hydrolase subdomains' for particular source types:
Journal articles Dissertations / Theses
We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!

To the bibliography