Academic literature on the topic 'Splenomegaly (Enlarged liver)'

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Journal articles on the topic "Splenomegaly (Enlarged liver)"

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K. Al-Malaak, Maha. "Histopathological changes on Splenomegaly induced in Experimental rats Wistar albino." AL-QADISIYAH MEDICAL JOURNAL 10, no. 18 (2017): 50–62. http://dx.doi.org/10.28922/qmj.2014.10.18.50-62.

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This study was aimed to evaluate histopathological changes in experimental rats with induced splenomegaly and liver fibrosis by administering thioacetamid (TAA). Liver fibrosis was clearly noticed in all experimental rats after intraperitoneally injected with a dose (200mg/kg) body weight for 8 weeks ,while control rats injected with buffered saline.The body , spleen and liver weight were recorded , also ratio of liver and spleen per body weight was estimated.Macroscopical changes including (colour, size, congested, signs of fibrosis, irregularity, nature of surface) regarded to liver and sple
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Song, Xie, Hong-Qiang Chen, Yu-Xin Chen, et al. "Individualized Management of Hepatic Diseases in Hereditary Hemorrhagic Telangiectasia." American Surgeon 77, no. 3 (2011): 281–85. http://dx.doi.org/10.1177/000313481107700314.

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Liver involvement in patients with hereditary hemorrhagic telangiectasia (HHT) has not been fully characterized in China. The clinical manifestations, imaging studies, results of treatment in six patients and symptomatic liver involvement were analyzed. Patients included three women and three men with age from 35 to 62 years old. Two patients presented with shortness of breath, one patient with anemia and splenomegaly, and one with chronic gastrointestinal bleeding; the remaining two were asymptomatic. CT and CT angiography (CTA) showed arterioportal and arteriovenous shunting in liver. CTA sh
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Jehangir, Khan, Munir Waqas, Tarin Khan Bakht, Ahmad Zaheer, Ahmad Shams Waqas, and Khan Asar. "Dengue outbreak 2013: Clinical profile of patients presenting at DHQ Burner and THQ Shangla, Khyber Pakhtunkhwa, Pakistan." Biohelikon 3 (January 1, 2015): 1–4. https://doi.org/10.5281/zenodo.816342.

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We evaluated the clinical features, disease severity, laboratory findings and outcome of serologically confirmed cases of Dengue fever in Patients during the recent outbreak in two districts (Buner & Shangla) in 2013, Khyber Pkhtunkhwa, Pakistan. We encountered 320 cases of Dengue fever during 5 months period (July to November, 2013). The dengue infection rate in females (180: 56%.2) was higher as compared to males (140: 43.8%). The dengue infections were more frequently seen in the post-monsoon season than in the monsoon period. The death ratio in the overall weighted prevalence was 0%. A
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Khurana, Ritika, Anju Aggarwal, Aashima Dabas, and Natasha Gupta. "Massive hepatomegaly in a neonate: an unusual cause." International Journal of Contemporary Pediatrics 4, no. 1 (2016): 274. http://dx.doi.org/10.18203/2349-3291.ijcp20164618.

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A female neonate presented with progressive abdominal distension. Liver was palpable, 11 cm below costal margin and a spleen of 10 cm. USG abdomen revealed massive hepatomegaly with multiple nodules in liver, kidney size and texture being normal. Contrast enhanced CT scan of the abdomen was suggestive of enlarged multinodular liver with splenomegaly. Liver biopsy revealed replacement of liver architecture by small rounded cells, which were positive for synaptophysin and S100 stains suggestive of neuroblastoma. A repeat abdominal radiological evaluation revealed a small 2 x 1 cm mass in left su
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OKADA, S., K. TAGAWA, R. WADA, Y. YAGUCHI, Y. KASHIMA, and A. NISHIMORI. "Enzootic bovine leukosis accompanied by splenomegaly in an 8-month-old calf." Journal of the Hellenic Veterinary Medical Society 71, no. 1 (2020): 2080. http://dx.doi.org/10.12681/jhvms.22969.

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In this report, an 8-month-old calf (crossbred, Holstein × Japanese Black) developed fever and accompanied abomasum displacement. Blood chemical test showed remarkably high values of white blood cell count and heteromorphic lymphocytes. In pathological appraisal, enlarged splenomegaly and swelling of the lymph nodes were observed. Histopathological examination revealed invasion of tumor cells derived from B1 cells into systemic lymph nodes, liver and spleen. The provirus loads of bovine leukemia virus (BLV) was 1,439 copies per 10 ng DNA by using real time PCR. In conclusion, this case was dia
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Dehghani, Seyed Mohsen, Amir Saeidi, Farzaneh Nejati, et al. "Clinical and Paraclinical Findings in Children With Congenital Hepatic Fibrosis: A Single Center 10-Year Study." Hospital Practices and Research 5, no. 2 (2020): 42–46. http://dx.doi.org/10.34172/hpr.2020.09.

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Background: Congenital hepatic fibrosis (CHF) is an autosomal hereditary disorder affecting the porto-biliary system. It is a rare hereditary disorder often presenting in childhood or adolescence with hepatomegaly, splenomegaly, and gastrointestinal bleeding. A timely diagnosis of organomegalies by sonography can prevent esophageal varices. Liver transplantation is now the only cure for CHF. Objectives: The current study aimed to determine clinical and paraclinical findings in patients diagnosed with CHF from 2008 to 2017. Methods: This was a descriptive cross-sectional study of all children &
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Djordjevic, Jelena, Petar Svorcan, Dusica Vrinic, and Branka Dapcevic. "Splenomegaly and thrombocytopenia in patients with liver cirrhosis." Vojnosanitetski pregled 67, no. 2 (2010): 166–69. http://dx.doi.org/10.2298/vsp1002166d.

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Backgroud/Aim. Splenomegaly is a frequent finding in patients with liver cirrhosis and portal hypertension and may cause hypersplenism. The occurrence of thrombocytopenia in those patients can be considered as an event with multiple etiologies. Two mechanisms may act alone or synergistically with splenic sequestration. One is central which involves either myelosuppression because of hepatitis viruses or the toxic effects of alcohol abuse on the bone marrow. The second one involves the presence of antibodies against platelets. It also depends upon the stage and etiology of liver disease. The ai
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Valentine, B. A., and S. P. Mcdonough. "B-Cell Leukemia in a Sheep." Veterinary Pathology 40, no. 1 (2003): 117–19. http://dx.doi.org/10.1354/vp.40-1-117.

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Necropsy examination was performed on an 8.5-year-old Finnish ewe euthanatized because of progressive respiratory distress, cachexia, and weakness. Significant postmortem findings included a diffusely enlarged, dark-red friable liver, mild splenomegaly, and mild mesenteric lymphadenopathy. Examination of multiple tissue sections revealed intravascular atypical mononuclear cells in all tissues examined, with a leukemic pattern of infiltration of mesenteric lymph nodes, liver, lung, and spleen. Neoplastic cells were positive for CD79a and negative for CD-3, BLA.36, and CD68 leukocytic markers. T
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Curovic Rotbain, Emelie, Dennis Lund Hansen, and Henrik Frederiksen. "The Data Quality of Splenomegaly ICD-10 Diagnoses in a Population-Based Hospital Discharge Registry: A Preliminary Analysis." Blood 126, no. 23 (2015): 5571. http://dx.doi.org/10.1182/blood.v126.23.5571.5571.

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Abstract Background Splenomegaly is a common finding in general medical patients. The cause of splenomegaly is often found outside the spleen and therefore an extensive diagnostic medical work-up is frequently required. There is very little data on the distribution of causal diagnoses and, to the best of our knowledge, accurate data on the risk of hematological malignancies, hepatic diseases and storage diseases among patients with splenomegaly have never been reported. The aim of this pilot study is to investigate the validity of the splenomegaly ICD-10 diagnoses, in order to ascertain if a n
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Jakobovich, E., B. Koplewitz, E. Marva, and E. Granot. "Yersinia enterocoliticaInfection Simulating Lymphoproliferative Disease, after Liver Transplant." Case Reports in Transplantation 2014 (2014): 1–3. http://dx.doi.org/10.1155/2014/923058.

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We describe a 14-year-old girl, who was 13 y after liver transplantation for biliary atresia with an unremarkable postoperative course. She presented with fever of up to 40°C, extreme fatigue, malaise, anorexia, and occasional vomiting. On physical examination the only finding was splenomegaly. Lab results showed hyperglobulinemia and an elevated sedimentation rate. Liver function tests were normal except for mild elevation ofγGTP. Abdominal U/S and CT demonstrated an enlarged spleen with retroperitoneal and mesenteric lymph nodes enlargement. An exhaustive evaluation for infectious causes, au
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Book chapters on the topic "Splenomegaly (Enlarged liver)"

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Lee, Christine U., and James F. Glockner. "Case 2.31." In Mayo Clinic Body MRI Case Review, edited by Christine U. Lee and James F. Glockner. Oxford University Press, 2014. http://dx.doi.org/10.1093/med/9780199915705.003.0062.

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53-year-old woman with chronic liver disease Axial fat-suppressed 2D SSFP images (Figure 2.31.1) demonstrate a nodular cirrhotic liver with splenomegaly and enlarged patent umbilical veins. Subvolume MIP (Figure 2.31.2) and VR (Figure 2.31.3) images reconstructed from a portal venous phase postgadolinium 3D SPGR acquisition again demonstrate large paraumbilical varices....
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