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Dissertations / Theses on the topic 'Stem progenitor cell'

Author: Grafiati
Published: 3 June 2025
Last updated: 31 July 2025

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1

Prater, Michael David. "Progenitor and stem cell potential of mammary myoepithelial cells." Thesis, University of Cambridge, 2013. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.648364.

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2

Giraddi, Rajashekharagouda. "Cell cycle kinetics of mammary stem and progenitor cells." Thesis, University of Cambridge, 2013. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.607789.

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3

Malandraki-Miller, Sophia. "Enhancing progenitor cells for cell therapy after myocardial infarction." Thesis, University of Oxford, 2016. https://ora.ox.ac.uk/objects/uuid:205043f4-e3e0-4947-9afc-b43f1543e0bd.

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Based on data from the World Healthcare Organisation, cardiovascular diseases are the primary cause of disease-related death globally, with myocardial infarction (MI) being the most prevalent. If not treated effectively, MI can progress to heart failure (HF). With 70 million prescriptions for HF in 2014 and 515 people in the UK being hospitalised daily with MI, the British Heart Foundation calls for novel robust treatments. Even though cardiac stem cell (CSC) therapy for MI has been under investigation for more than a decade, there still has not been a consensus over the identity of the adult
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4

Dause, Tyler. "Investigating Neural Stem and Progenitor Cell Intracrine Signaling." The Ohio State University, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=osu1555618643450352.

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5

Saleh, Lubaid. "Small molecule mediated targeting of haematopoietic stem/progenitor cell and leukaemic stem cell function." Thesis, Cardiff University, 2017. http://orca.cf.ac.uk/105172/.

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Haematopoietic stem cells (HSC) are a rare population of cells that have the ability to self-renew and differentiate giving rise to various blood lineages, thereby reconstituting the whole haematopoietic system. This is an essential characteristic, exploited in bone marrow transplantation therapy in response to myeloablative treatment. Due to their rarity, the lack of sufficient HSC numbers for transplantation has proved to be a major clinical issue. Separately, in the development of leukaemia, acquired mutations in HSCs give rise to malignant cells. These cells, like HSCs, have the ability to
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6

Behbahani, John. "The Role of MicroRNAs in Endothelial Progenitor Cell Function." Thesis, Université d'Ottawa / University of Ottawa, 2016. http://hdl.handle.net/10393/35080.

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Cultures of peripheral blood mononuclear cells (MNCs) give rise to at least two different variants of endothelial progenitor cells (EPCs), early and late outgrowth EPCs. We investigated whether microRNAs in early and late EPCs could serve as markers of internal processes that can be exploited to distinguish cell identity and functional capacity. We hypothesized that as MNCs give rise to early and late EPCs, there is a gradual change in total microRNA profile, reflecting a total change in processes within the predominant cell population. Using a candidate microRNA array, early and late EPCs sho
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7

Kwee, Edward. "Quantitative Assays for Characterizing Stem and Progenitor Cell Populations." Case Western Reserve University School of Graduate Studies / OhioLINK, 2017. http://rave.ohiolink.edu/etdc/view?acc_num=case1474906437312739.

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8

Kollek, Matthias [Verfasser], and Miriam [Akademischer Betreuer] Erlacher. "Improvement of hematopoietic stem cell transplantations by transient apoptosis inhibition in donor stem and progenitor cells." Freiburg : Universität, 2016. http://d-nb.info/1136263462/34.

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9

Greenhowe, Jennifer. "Stem and progenitor cells in wound healing." Thesis, University of Oxford, 2014. http://ora.ox.ac.uk/objects/uuid:87a9a7a1-b595-458a-913f-64497174f988.

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As more patients with large body surface area burns are surviving and requiring reconstructive surgery, there is a necessity for advances in the provision of bioengineered alternatives to autologous skin cover. The aims of this Thesis are to identify feasible source tissues of Endothelial Colony Forming Cells and Mesenchymal Stem/Stromal Cells for microvascular network formation in vitro with three-dimensional dermal substitute scaffolds. The working hypothesis is that pre-vascularised dermal scaffolds will result in better quality scarring when used with split thickness skin grafts. Human umb
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10

Hopp, I. "Novel synthetic biomaterials for kidney-derived progenitor/stem cell differentiation." Thesis, University of Liverpool, 2016. http://livrepository.liverpool.ac.uk/3004383/.

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End-stage kidney disease is increasing in prevalence and is associated with high levels of morbidity and mortality. At present, the only treatment options are dialysis or renal transplantation. However, dialysis is very costly and is associated with high levels of morbidity, whereas the problem with transplantation is that there is a shortage of organ donors. For these reasons, over recent years, there has been an increasing interest in developing novel therapies in the field of regenerative medicine including stem cell based therapies and tissue engineering. Stem cells could be used in a numb
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11

Hsu, Jui-Cheng. "Transcriptional regulation of the stem cell/progenitor gene c-Myb." Thesis, University of Nottingham, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.546247.

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12

Larsson, Jimmy. "Neural stem and progenitor cells cellular responses to known and novel factors /." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis : Univ.-bibl. [distributör], 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-110722.

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13

Tabayoyong, William Borj. "Engraftment of embryonic stem cell-derived hematopoietic progenitor cells is regulated by natural killer cells." Diss., University of Iowa, 2011. https://ir.uiowa.edu/etd/1089.

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Embryonic stem (ES) cells possess the remarkable ability to form cells and tissues from all three germ layers, a characteristic known as pluripotency. In particular, the generation of ES cell-derived hematopoietic cells could serve as an alternate source of hematopoietic stem cells for transplantation in place of bone marrow cells, which are limited by donor availability and high immunogenicity. The advantages of ES cell-derived hematopoietic cells over bone marrow cells include a greater proliferative capacity, which alleviates the problems of donor shortage, and low level expression of MHC a
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14

Knight, Julia. "Roles of Fas in Neural Progenitor Cell Differentiation, Survival, and Immune-Cell Interactions." ScholarWorks @ UVM, 2011. http://scholarworks.uvm.edu/graddis/124.

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Multiple sclerosis (MS) is a leading cause of neurological disability in young adults. Although current treatments can reduce symptomology and relapse rate, they are unable to prevent the chronic neurodegeneration that occurs at later stages. MS pathology is mediated by complex interactions between invading immune cells, neurons, glia, and endogenous stores of neural progenitor cells (NPCs). Factors critical to NPC/immune cell communication as well as the survival, differentiation, and proliferation of NPCs are not well defined. Elucidation of these factors will allow for the advancement of NP
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15

Jacobs, Peter. "Immunohaematopoietic stem and progenitor cell transplantation - a thirty year prospective and systematic research investigation." Thesis, Stellenbosch : University of Stellenbosch, 2010. http://hdl.handle.net/10019.1/5232.

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16

Mahdipour, Elahe. "Haematopoietic stem/progenitor cell migration and differentiation in response to injury." Thesis, University of Manchester, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.518453.

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17

Chang, Chao-Hui. "Haematopoietic stem/progenitor cell interactions with the bone marrow vascular niche." Thesis, University of Oxford, 2013. http://ora.ox.ac.uk/objects/uuid:452da334-bd4e-45c7-a7bd-fc8767d1239c.

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Umbilical cord blood (UCB) is used as a source of haematopoietic stem cells (HSCs) for transplantation but shows defective homing to the bone marrow niche and delayed haematological reconstitution. Following transplantation, HSCs will home to the bone marrow in response to the CXCL12 chemokine, adhere to the bone marrow sinusoidal endothelial cells and then migrate into and lodge in bone marrow niches. In addition to CXCR4, a variety of molecules have been described as being important in these processes. In this laboratory, junctional adhesion molecule-A (JAM-A) was shown to be expressed on hu
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18

NIU, HONG. "Functional Polymeric Hydrogels in Stem/Progenitor Cell Therapy and Therapeutic Angiogenesis." The Ohio State University, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=osu1543406270126261.

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19

Faijerson, Jonas. "Neural stem/progenitor cells in the post-ischemic environment : proliferation, differentiation and neuroprotection /." Göteborg : Center for Brain Repair and Rehabilitation, Institute of Neuroscience and Physiology, Göteborg University, 2007. http://hdl.handle.net/2077/4516.

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20

Jambi, Majed. "Differentiation of Human Atrial Myocytes from Endothelial Progenitor Cell-Derived Induced Pluripotent Stem Cells." Thèse, Université d'Ottawa / University of Ottawa, 2014. http://hdl.handle.net/10393/31158.

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Recent advances in cellular reprogramming have enabled the generation of embryoniclike cells from virtually any cell of the body. These inducible pluripotent stem cells (iPSCs) are capable of indefinite self-renewal while maintaining the ability to differentiate into all cell types. Nowhere will this technology have a greater impact than in the ability to generate disease and patient-specific cell lines. Here we explore the capacity of human iPSCs reprogrammed from peripheral blood endothelial progenitor cells lines to differentiate into atrial myocytes for the study of patient specific atrial
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21

Liu, Yi. "LATEXIN’S ROLE IN REGULATING HEMATOPOIETIC STEM AND PROGENITOR CELLS." UKnowledge, 2013. http://uknowledge.uky.edu/physiology_etds/11.

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Previous studies in our lab identified a novel gene, latexin (Lxn), that regulates murine hematopoietic stem cells through balancing apoptosis, self-renewal and proliferation. In these dissertation studies, I performed a series of experiments to examine the function of Lxn using a Lxn conventional knockout mouse, and characterize Lxn’s role in the presence of hematopoietic stresses such as ionizing radiation, cytokines induced-mobilization, and hematopoietic malignancy. The first series of experiments was designed to determine the role of Lxn in hematopoiesis under homeostatic conditions. I fo
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22

Genander, Maria. "No guts, no glory EphB mediated signaling in intestinal stem and progenitor cells /." Stockholm : Department of Cell and Molecular Biology, Karolinska Institutet, 2009. http://diss.kib.ki.se/2009/978-91-7409-735-1/.

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23

Finan-Marchi, Amanda Rose. "THE SYSTEMIC STEM CELL RESPONSE TO CARDIAC PRESSURE OVERLOAD." Case Western Reserve University School of Graduate Studies / OhioLINK, 2012. http://rave.ohiolink.edu/etdc/view?acc_num=case1333897602.

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24

Traveset, Martínez Laia 1992. "New insights into transcription that preserve hematopoietic stem cell homeostasis." Doctoral thesis, Universitat Pompeu Fabra, 2020. http://hdl.handle.net/10803/670105.

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Maintenance of steady-state and stress-adapted hematopoiesis depends on the fitness of hematopoietic stem and progenitor cells (HSPCs) in the bone marrow. Hematopoietic stem cells (HSCs) can adapt to stress by expanding their numbers and increasing the output of blood cells. This dynamic and highly complex process needs to be fully regulated in order to maintain a balance between the differentiation of HSCs and the need to keep a constant pool of HSCs. However, the molecular machinery in charge of this tight regulation has yet to be fully characterized. HSCs represent a small proportion inside
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25

Bird, Thomas Graham. "Liver regeneration by hepatic progenitor cells." Thesis, University of Edinburgh, 2011. http://hdl.handle.net/1842/5634.

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The liver is the largest solid organ in the body and is frequently the site of injury. During disease, liver injury is usually compensated for by exceptionally efficient regeneration which occurs both from differentiated epithelia and also from an undifferentiated cell population with stem cell like qualities known as hepatic progenitor cells (HPCs). HPCs are particularly active during massive or chronic liver injury and therefore are an attractive target for much needed novel therapies to enhance regeneration in patients for whom the only current effective therapy is liver transplantation. St
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26

Yu, Yin. "Identification and characterization of cartilage progenitor cells by single cell sorting and cloning." Thesis, University of Iowa, 2012. https://ir.uiowa.edu/etd/3414.

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Cartilage lesion is a fairly common problem in orthopaedic practise. It is often a consequence of traumas, inflammatory conditions, and biomechanics alterations. However, as an avascular and aneural tissue, articular cartilage has minimal healing ability. Over the past decades, surgeons and scientists have proposed a nubmer of treatment strategies to promote restoration of articular cartilage, like arthroscopic lavage, microfracture surgery, osteochoncral autografts and allografts, autologous chondrocyte implantation, and other cell-based repairs. Nevertheless, these solutions often result in
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27

Simpson, David Lemar. "A tissue engineered approach to progenitor cell delivery and myocardial repair." Diss., Georgia Institute of Technology, 2009. http://hdl.handle.net/1853/37187.

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Heart failure accounts for more deaths in the United States than any other pathology. Unfortunately, repairing the heart after pathological injury has become an overwhelming task for physicians and researchers to overcome. Fortunately, cellular cardiomyoplasty has emerged as a promising solution for sufferers of heart failure. Such a therapy is limited in efficacy due to poor engraftment efficiencies, however. To address this issue, we have developed a tissue engineered vehicle for cell delivery. Use of a "cardiac patch" resulted in localized and efficient delivery of human mesenchymal stem
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28

Bondue, Antoine. "Mesp1 functions in multipotent cardiovascular progenitor specification." Doctoral thesis, Universite Libre de Bruxelles, 2009. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/210319.

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During embryonic development, multipotent cardiovascular progenitor cells (MCPs) are specified from early mesoderm. Although the core cardiac transcriptional machinery acting during cardiac cell differentiation is relatively well known, the molecular mechanism acting upstream of these cardiac transcriptional factors, and promoting cardiac progenitor specification from early mesoderm remains poorly understood. We used embryonic stem cell (ESC) differentiation as a model to dissect the molecular mechanisms implicated in cardiovascular progenitor specification. Using ESCs, in which gene expressio
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29

Schabort, Elske Jeanne. "The effect of TGF-[beta] isoforms on progenitor cell recruitment and differentiation into cardiac and skeletal muscle /." Link to the online version, 2007. http://hdl.handle.net/10019.1/1295.

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30

Fair, Joel Vincent. "Gli2 Accelerates Cardiac Progenitor Gene Expression During Mouse Embryonic Stem Cell Differentiation." Thesis, Université d'Ottawa / University of Ottawa, 2014. http://hdl.handle.net/10393/31579.

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The Hedgehog (HH) signalling pathway and its primary transducer, GLI2, regulate cardiomyogenesis in vivo and in differentiating P19 embryonal carcinoma (EC) cells. To further assess the role of HH signalling during mouse embryonic stem (mES) cell differentiation, we studied the effects of GLI2 overexpression during mES cell differentiation. GLI2 overexpression resulted in temporal enhancement of cardiac progenitor genes, Mef2c and Nkx2-5, along with enhancement of Tbx5, Myhc6, and Myhc7 in day 6 differentiating mES cells. Mass spectrometric analysis of proteins that immunoprecipitate with GLI2
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31

Cova, Giovanni. "The role of Helios in the hematopoietic stem and progenitor cell development." Thesis, Strasbourg, 2019. http://www.theses.fr/2019STRAJ092.

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Les cellules souches et progénitrices hématopoïétiques (CSPH) produisent les cellules sanguines durant toute la vie. Elles sont divisées en cellules souches indifférenciées (CSH) et en cellules progénitrices multipotentes engagées (MPP). Les MPP sont hétérogènes et composées de cellules progénitrices multipotentes engagées vers les lignages érythro-mégacaryocytaires (MPP2), myéloïdes (MPP3) et lymphoïdes (MPP4). Malgré que ces populations cellulaires soient bien définies, les mécanismes moléculaires gouvernants leurs différenciations restent en grande partie encore inconnus. Nous avons montré
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32

Patel, Nirmal Praful School of Medicine UNSW. "Olfactory progenitor cell transplantation into the mammalian inner ear." Awarded by:University of New South Wales. School of Medicine, 2006. http://handle.unsw.edu.au/1959.4/26180.

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A practical consideration in the development of cellular therapy technology for the inner ear is the development of an in vitro model for assessing the optimal conditions for successful application of cells. The first part of this thesis describes the adaptation of the cochleovestibular structure harvested from P1 mouse pups for analysis of factors critical for the optimal implantation of stem cells in the inner ear. Results of these studies establish that the c17.2 neural stem cell line can be introduced into the cochleovestibular structure in vitro. Using this model, c17.2 cells demonstrated
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33

Chen, Yan. "EFFECTS OF GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR (GDNF) ON STEM/PROGENITOR CELL PROLIFERATION AND DIFFERENTIATION." UKnowledge, 2005. http://uknowledge.uky.edu/gradschool_diss/233.

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Stem/progenitor cells are present in the adult brain; they undergo constantproliferation and differentiate into mature neurons in certain brain areas, a phenomenoncalled neurogenesis. This study investigated the effects of GDNF, a potent trophic factorof dopaminergic neurons, on neurogenesis in the brain. Nestin and 5-Bromo-2'-deoxyuridine (BrdU) were used as stem/progenitor cells markers.First, we observed extensive bilateral increases of stem/progenitor cells in thedentate gyrus and substantia nigra after continuous infusion of GDNF into the normal ratbrain. However, none of the BrdU+ cells
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34

Wesser, Andrea. "USER-DEFINED PATTERNING OF NEURAL PROGENITOR CELLS ON 3D MICROPILLAR ARRAYS USING ROUND CROSS-SECTIONAL GEOMETRY, SPECIFIC DIMEN." Master's thesis, University of Central Florida, 2008. http://digital.library.ucf.edu/cdm/ref/collection/ETD/id/3973.

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The ability to control stem cell functions, particularly neuronal progenitors, has long since been believed to be the key to successful treatment of neurodegenerative disorders such as Alzheimer's, Parkinson's and accidents involving head trauma. The neurology field calls for many new solutions to address the controlled neural stem cell seeding and placement of cells for neural tissue regeneration. Self-assembled monolayers (SAM) from the alkanethiol group provide a straightforward applicable, reliable treatment for cell adhesion. An ODT/gold treatment was used to adhere the cells to patterned
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35

Pepperell, Emma E. "The regulation of stem cell engraftment." Thesis, University of Oxford, 2013. http://ora.ox.ac.uk/objects/uuid:873a14b9-6c7b-4643-bb34-4e1679d4f734.

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The engraftment of haemopoietic stem/progenitor cells (HSPCs) from umbilical cord blood (UCB) into adult recipients, although advantageous in terms of sourcing units, the decreased need to match donor and recipient and reduced risk of graft versus host disease (GvHD), is delayed compared to grafts using HSPCs from mobilised peripheral blood (MPB) or bone marrow (BM). One reason for this is the limited number of HSPCs (CD34+/CD133+ cells) in a unit of UCB compared to MPB or BM. The CXCR4-CXCL12 axis is widely recognised as a key player in the bone marrow homing, retention, and engraftment of HS
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36

Forde, Sinead. "The role of the human sialomucin CD164 in regulating stem/progenitor cell fate." Thesis, University of Oxford, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.442950.

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37

Al, Ajmi Nouf Hejab S. H. "Role of oxidative stress and telomerase on haematopoietic stem and progenitor cell ageing." Thesis, University of Newcastle upon Tyne, 2014. http://hdl.handle.net/10443/2503.

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Ageing is associated with the functional decline of both haematopoietic stem and endothelial progenitor cells (HSPCs and EPCs), leading to an imbalance between cellular damage and repair. Telomeres are the end caps of chromosomes that maintain chromosomal integrity and shorten with age. Telomerase is the enzyme responsible for telomere replication. The absence of telomerase leads to premature ageing. Oxidative stress as well as metabolic stress and short telomeres are key contributors to the manifestation of different age-related diseases. However, the exact effect of these factors on HSPCs an
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38

Futrega, Katarzyna. "Device and application development for haematopoietic stem and progenitor cell (HSPC) and mesenchymal stromal cell (MSC) 3D spheroid cultures." Thesis, Queensland University of Technology, 2016. https://eprints.qut.edu.au/92605/1/Katarzyna_Futrega_Thesis.pdf.

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With an overall aim to improve haematopoietic stem/progenitor cell (HSPC) and mesesnchymal stromal cells (MSC) 3D culture systems, this PhD Thesis addressed the following four interlinked AIMs: (1) The development of a high throughput microwell platform that enabled evaluation of MSC spheroid potential to expand HSPC in vitro; (2) Utilization of the high throughput microwell platform to manufacture HSPC/MSC spheroids to improve the efficacy of direct bone marrow transplantation; (3) The development of an improved microwell platform that retains spheroids within discrete microwells throughout c
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Yang, Yawei. "ZNF335: A Novel Regulator of Stem Cell Proliferation and Cell Fate in the Cerebral Cortex." Thesis, Harvard University, 2012. http://dissertations.umi.com/gsas.harvard:10682.

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Though development of the cerebral cortex is of singular importance to human cognition, it remains very poorly understood. Microcephaly, or "small head," is a neurodevelopmental disorder causing significantly reduced cerebral cortex size, and the disease has proved to be a useful model system for elucidating the steps essential for proper cortical development and cognitive function. Many known microcephaly gene products localize to centrosomes, regulating cell fate and proliferation, however, the elucidation of different microcephaly genes with different functions may shed light on previously
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40

Selander, Lars. "In vivo and in vitro approaches to induce beta cells from stem and progenitor cells." Doctoral thesis, Umeå : Umeå University, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-25813.

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41

Kilcoyne, Karen. "Early life programming of adult Leydig cell function." Thesis, University of Edinburgh, 2014. http://hdl.handle.net/1842/9533.

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There is increasing evidence to suggest that fetal events can predetermine reproductive health and general wellbeing in adulthood, a process termed 'fetal programming'. This refers to the association between altered fetal growth/development and health disorders in adulthood e.g. the metabolic syndrome, which is linked to low male testosterone levels. Studies from both Europe and the USA have shown that adult male testosterone levels have been declining, independent of age. As low testosterone levels in aging men are associated with increased morbidity and mortality, this highlights the importa
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Yu, Yin. "Articular cartilage tissue engineering using chondrogenic progenitor cell homing and 3D bioprinting." Diss., University of Iowa, 2015. https://ir.uiowa.edu/etd/6895.

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Articular cartilage damage associated with joint trauma seldom heals and often leads to osteoarthritis (OA). Current treatment often fails to regenerated functional cartilage close to native tissue. We previously identified a migratory chondrogenic progenitor cell (CPC) population that responded chemotactically to cell death and rapidly repopulated the injured cartilage matrix, which suggested their potential for cartilage repair. To test that potential we filled experimental full thickness chondral defects with an acellular hydrogel containing SDF-1α. We expect that SDF-1α can increase the re
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Perrini, C. "EQUINE AND BOVINE MICROVESICLES DERIVED FROM AMNIOTIC PROGENITOR CELLS IN REGENERATIVE AND REPRODUCTIVE TOPICS." Doctoral thesis, Università degli Studi di Milano, 2017. http://hdl.handle.net/2434/490022.

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Durante questo progetto di dottorato sono stati condotti studi per comprendere la capacità delle cellule mesenchimali amniotiche (AMCs) di agire attraverso meccanismi paracrini. La prima fase del disegno sperimentale ha valutato l’efficacia delle AMCs sulla proliferazione delle cellule endometriali (EDCs) in assenza di un contatto cellula-cellula. Le EDCs sono state co-coltivate in un sistema trans-well con le AMCs o sono state coltivate in presenza del loro medium condizionato (CM). In entrambe le condizioni sperimentali è stato osservato un aumento del tasso di proliferazione delle EDCs defi
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Kimura, Azuma. "Small molecule AT7867 proliferates PDX1-expressing pancreatic progenitor cells derived from human pluripotent stem cells." Kyoto University, 2019. http://hdl.handle.net/2433/242422.

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45

Alyamani, Najiah. "Molecular-genetics studies of organophosphate induced neurodegeneration in differentiating mammalian cell lines and neural progenitor stem cells." Thesis, Nottingham Trent University, 2018. http://irep.ntu.ac.uk/id/eprint/35003/.

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Organophosphorus (OP) pesticides are widely used despite evidence they cause neurotoxicity after exposure. The primary target for OPs is acetylcholinesterase, but there is evidence they can inhibit other cellular proteins including cytoskeletal and axon growth associated proteins, which are implicated in nervous system development. Furthermore, little is known about the ability of OPs to cause genotoxicity. The objectives of this study were to evaluate the effects of selected OPs on neurite outgrowth, expression of cytoskeletal proteins and associated gene expression levels, and to investigate
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46

Roubelakis, Maria G. "The role of SHP-2 and its partners in regulating stem/progenitor cell fate." Thesis, University of Oxford, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.400441.

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47

Li, Hang. "Neural Stem/Progenitor Cell 3-D Differentiation for Repair of Central Nervous System Injuries." University of Akron / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=akron1428248647.

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48

Hernandez, Ivan. "PRIMING CARDIOVASCULAR STEM CELLS FOR TRANSPLANTATION USING SHORT-TERM HYPOXIA." CSUSB ScholarWorks, 2016. https://scholarworks.lib.csusb.edu/etd/348.

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Conventional medical treatments fail to address the underlying problems associated with the damage inflicted by a coronary event. Thus, the long-term prognosis of patients admitted for heart failure is disheartening, with reported survival rates of 25 percent. Recent advances in stem cell research highlight the potential benefits of autologous stem cell transplantation for stimulating repair in heart tissue. However, a majority of those suffering from cardiovascular diseases are older adults whose autologous cells no longer possess optimum functional capacity. Additional work is needed to iden
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49

Guthrie, Steven Mitchell. "Hemangioblasts from hematopoietic stem cells to endothelial progenitor cells and their effector molecules /." [Gainesville, Fla.] : University of Florida, 2005. http://purl.fcla.edu/fcla/etd/UFE0010068.

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Thesis (Ph.D.)--University of Florida, 2005.<br>Typescript. Title from title page of source document. Document formatted into pages; contains 95 pages. Includes Vita. Includes bibliographical references.
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Masek, Lisa Christina. "The study of adhesive interactions between haemopoietic progenitor cells and bone marrow sinusoidal endothelial cells." Thesis, University of Southampton, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.242854.

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