Academic literature on the topic 'Super Disintegrates'

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Journal articles on the topic "Super Disintegrates"

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Sneha, Ms Shinde. "Review Article A Detailed Study on Disintegrating Agents and an Overview on Oral Disintegration Tablet." INTERANTIONAL JOURNAL OF SCIENTIFIC RESEARCH IN ENGINEERING AND MANAGEMENT 08, no. 04 (2024): 1–5. http://dx.doi.org/10.55041/ijsrem30535.

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Nowadays, the administration of drugs through the oral route is becoming less common, accounting for only about 75% of all drug administrations compared to other routes. A new type of dosage form called oral disintegrating tablets has gained popularity in recent decades due to their rapid disintegration and dissolution. These tablets disintegrate in the mouth within seconds (25-40 seconds) without the need for water, as the oral mucosa alone is sufficient for the tablet to dissolve. The selection of a suitable disintegrating agent is crucial to achieve optimal bioavailability. A preparation ma
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Iswariya, V. T., Nambaaru Sailaja, CH Vamsi Krishna, and G. S. Annammadevi. "Natural Super-Disintegrant Agents Used in Various Oral Solid Dosage Forms." Journal of Drug Delivery and Therapeutics 11, no. 1 (2021): 110–13. http://dx.doi.org/10.22270/jddt.v11i1.4681.

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Super-disintegrating agents are one of the ingredients used in pharmaceutical solid dosage forms. These substances play a vital role in formulation design. Natural super-disintegrants have gained more popularity due to their oral bioavailability. It disintegrates the tablets into smaller particles to enhance the dissolution rate. Fast dissolving, chewable tablets, and other orally administered dosage forms consist of super-disintegrating agents which shows rapid and quick action. Natural super disintegrating agents in pharmaceutical dosage forms are very effective due to their ecofriendly natu
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Sujit, S. Shinde* Madan k. Shinde Avinash A. Bhagat Sachitanand Balaji Biradar. "Formulation And Evaluation Of Fast Dissolving Sodium Diclofenac Sodium Tablet." International Journal in Pharmaceutical Sciences 2, no. 5 (2024): 1761–74. https://doi.org/10.5281/zenodo.11400826.

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The present study was aimed to formulate, evaluate, and optimize a tablet that disintegrates and dissolved rapidly toshow a rapid onset action. Diclofenac sodium, non-steroidal- inflammatory, analgesic, and pyretic properties were selected asa model drug. Diclofenac sodium is among the most extensivelyused Non-steroidal anti-inflammatory drugs, employed inmucosal skeletal complaints, especially arthritis. In the present study, an attempt has been made to prepare fast dissolvingtablets of diclofenac sodium using super disintegrants like sodium starch Glycolate, Croscarmellose sodium, Crospovido
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Bhattacharya, Suhasis, Tanmay Mohanta, Sujit Das, and Rumpa Basak. "Orodispersible Tablet in Treatment of Migraine: Opportunities, Challenges and Recent Advancements." Journal of Drug Delivery and Therapeutics 11, no. 4 (2021): 149–56. http://dx.doi.org/10.22270/jddt.v11i4.4878.

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The most comfortable and choicely path of drug administration is oral route. Orodispersible tablets bring a revolution among all routes of drug administration as well as oral route of drug administration also. Orodispersible tablets are unit dosage form but it has unique characteristics. It disintegrates in the mouth within a minute for the presence of saliva where the presence of super disintegrates in the preparation. Especially, old and child have no chance to swallow as a result it is very acceptable for them. Migraine is a very well-known irritating condition for adult and female. Migrain
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K, Venkatesh, Ramu B, and Rajkamal B. "Formulation and Evaluation of Risperidone Fast Disintegrating Tablets by Using Co- processed Superdisintegrants." Pharmaceutical and Chemical Journal 3, no. 2 (2016): 334–42. https://doi.org/10.5281/zenodo.13754623.

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In the present work, an attempt has been made to develop fast disintegrating tablets of Risperidone. Novel method of co processed super disintegrates technology was employed to formulate the tablets. All the formulations were prepared by direct compression method using 8mm punch on 8 station rotary tablet punching machine. The blend of all the formulations showed god flow properties such as angle of repose, bulk density, tapped density. The prepared tablets were shown good post compression parameters and they passed all the quality control evaluation parameters as per I.P limits. Among all the
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M., Anusha, Varun Raj S., Krishna Srewe P.V., Divya Deepthi N., Evanjiline Ch., and Roopa Koteswari Ch. "Formulation and Development of Rosuvastatin Fast Dissloving Tablets using Natural Super Disintegrates." Research & Review: Drugs and Drugs Development 1, no. 2 (2019): 61–77. https://doi.org/10.5281/zenodo.3271091.

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<em>Rosuvastatin is in category of the drug class. It is used to treat high cholesterol and to block cardiovascular disease. The main aim of this study is to develop oral dispersible tablets of Rosuvastatin using different types of super disintegrates to enhance the disintegration and dissolution of Rosuvastatin to improve bioavailability of the drug. Many trials were made to prepare a satisfactory rosuvastatin oral dispersible tablet using direct compression and wet granulation method. Formulate tablets were examine with different parameters such as weight variation, hardness, friability, wet
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C., Haranath* T. Srikanth M. Suresh Krishna G. Chaithanya Barghav C. Mahesh Reddy. "FORMULATION AND INVITRO EVALUATION OF FAST DISINTEGRATING TABLETS OF AN ANTI-INFLAMMATORY DRUG." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES o6, no. 05 (2019): 10790–99. https://doi.org/10.5281/zenodo.3229226.

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<em>Oral disintegrating tablets are defined as the tablets that disperse or disintegrates in less than one minute in the mouth prior to being swallowed, which results in the rapid dissolution and absorption of the active pharmaceutical ingredient contained in the tablet, providing rapid onset of action. Aceclofenac is a poorly water-soluble drug. The solubility of the drug was enhanced by solid dispersion technique using mannitol as the carrier. In the present study, 9 formulations were developed by using different super disintegrants like cross povidone, sodium starchglycolate and cross carme
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Nimisha Solanki, Arpit Gawshinde, Komal Tikariya, Umesh K. Atneriya, and Dharmendra Solanki. "A Review on Orodispersible tablet." IJPAR JOURNAL 12, no. 3 (2023): 358–61. http://dx.doi.org/10.61096/ijpar.v12.iss3.2023.358-361.

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The oral route is the most important and recommended route of drug administration. Oral route is the safest and convenient route of drug delivery because of wide range of drugs are administered through this route. Oro dispersible tablets are novel oral drug-delivery system as they have improved patient compliance and have some additional advantages compared to other oral formulation. Oral dispersible tablet are solid unit dosage forms, which disintegrate or dissolves quickly in the mouth within a minute in the presence of saliva without chewing or water. The dosage form containing super disint
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M. Aruna, Samreen, and Shaik Harun Rasheed. "Formulation and evaluation of fast disintegrating tablets of metoprolol succinate using various superdisintegrants." International Journal of Research in Pharmaceutical Sciences and Technology 1, no. 2 (2019): 79–83. http://dx.doi.org/10.33974/ijrpst.v1i2.150.

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The aim of present work is to develop a fast disintegrating solid oral dosage form of Metoprolol succinate. The concept of fast dissolving drug delivery system emerged from the desire to provide patient with more conventional means of taking their medication. Problems associated with conventional tablets can be resolved by means of fast dissolving tablets when put on tongue these tablets disintegrate and dissolve rapidly in saliva without need of drinking water. The faster the drug disintegrates in to solution, the quicker the absorption and onset of clinical effect. Preformulation results rev
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Nandhini M, Voleti Vijaya Kumar, Suganya T, et al. "Formulation, development and evaluation of fast disintegrating tablet of dapsone by using natural super disintegrates." International Journal of Pharmaceutical Chemistry and Analysis 11, no. 3 (2024): 239–44. http://dx.doi.org/10.18231/j.ijpca.2024.034.

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The needof the fast-disintegrating tablets ever increasing day by day during the last decade. In this current research study, the effect of the natural super disintegrating agents in the Dapsone fast disintegrating tablets was compared. The natural super disintegrating agents were characterized for different physico chemical methods like Loss on drying, moisture content and Ash values.Dapsone was selected as a model drug, where the dapsone has low bioavailability due to this reason, dapsone solid dispersions were developed and the same was used to formulate the tablets. The formation of the so
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Dissertations / Theses on the topic "Super Disintegrates"

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Soulairol, Ian. "Etude des phénomènes liés à la conception de mini-comprimés orodispersibles par compression directe." Thesis, Montpellier, 2017. http://www.theses.fr/2017MONTT115/document.

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La possibilité d’administrer des formes sèches orales est encore de nos jours un enjeu dans certaines spécialités médicales telles que la pédiatrie, la neurologie ou la gériatrie. Les mini-comprimés orodispersibles présentent un intérêt majeur pour répondre à cette problématique.L’objectif de ce travail est d’étudier les différents phénomènes qui régissent la conception de cette forme pharmaceutique par compression directe.Trois axes de recherche ont été fixés pour la réalisation de ce travail : - Premièrement, étudier les paramètres de formulation et de fabrication des mini-comprimés orodispe
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Book chapters on the topic "Super Disintegrates"

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Noothi, Sadhana, Narender Malothu, and P. Vishnu. "Formulation and Characterization of Bilastine Oral Disintegrated Tablets Using Natural and Synthetic Super Disintegrants." In Current Trends in Drug Discovery, Development and Delivery (CTD4-2022). Royal Society of Chemistry, 2023. http://dx.doi.org/10.1039/9781837671090-00361.

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Bilastine (BLS) is a second-generation H1- antihistamine that is approved recently for the symptomatic treatment of chronic urticaria. The present investigation was to develop oral disintegrating tablets of BLS to produce a fast onset of action. In this study, an attempt was made to compare the effect of different natural and synthetic super disintegrants on the release profile of the formulation. The formulations (BF1-BF15) of BLS oral disintegrating tablets were prepared by direct compression technique using synthetic and natural super disintegrants (Chitosan, Fenugreek mucilage, Sodium star
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"Super Disintegrants: Characterization and Function." In Encyclopedia of Pharmaceutical Technology. CRC Press, 2013. http://dx.doi.org/10.1201/b19309-12.

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Y., Ismail, and V. Vijaya Kumar. "Design, Charecterization of Imidapril Mouth Dissolving Tablets Using Super Disintegrants." In Advanced Concepts in Pharmaceutical Research Vol. 4. B P International, 2024. http://dx.doi.org/10.9734/bpi/acpr/v4/6646c.

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Ismail, Y., and Voleti Vijaya Kumar. "Development and Assessment of Fast-Dissolving Tablets of Levocetirizine Dihydrochloride Using Super Disintegrants." In Pharmaceutical Science: New Insights and Developments Vol. 5. BP International, 2025. https://doi.org/10.9734/bpi/psnid/v5/4878.

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Devi, V. Rupa Sree, M. Sukanya, K. Ravi Shankar, G. Ramana Reddy, and KNV Chenchu Lakshmi. "Formulation, Preparation, and Evaluation of Nebivolol Fast-Dissolving Tablets by Using 32 Factorial Design." In Current Trends in Drug Discovery, Development and Delivery (CTD4-2022). Royal Society of Chemistry, 2023. http://dx.doi.org/10.1039/9781837671090-00510.

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Nebivolol comes under BCS Class II Classification, so there is a need to improve the dissolution rate. The motive of the current work is to formulate the fast-dissolving tablets of Nebivolol from optimised solid dispersion by allowing complexation using solid dispersions of PEG 4000, Starch 1500, Poloxamer 188, and β-cyclodextrin (β CD). Nebivolol tablets with fast dissolution characteristics employing βCD were prepared using a 32 factorial study employing by direct compression technique. Dissolution of Nebivolol from the β-CD complexes was rapid and higher when seen with that of Pure Nebivolo
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Sukanya, M., V. Rupa Sree Devi, K. Ravi Shankar, G. Ramana Reddy, and R. Anusha. "Optimization of Telmisartan Fast Dissolving Tablets by 32 Factorial Design." In Current Trends in Drug Discovery, Development and Delivery (CTD4-2022). Royal Society of Chemistry, 2023. http://dx.doi.org/10.1039/9781837671090-00533.

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Telmisartan belongs to BCS Class II drug and needs enhancement in dissolution rate. The main objective of the study is to produce rapid dissolving tablets of telmisartan by complexation with β-cyclodextrin(βCD) and by using solid dispersions of MCC, Starch 1500, PEG 4000, Primojel and Mannitol. Telmisartan tablets with fast dissolution characteristics employing βCD were prepared using 32 factorial design and were prepared by direct compression method. Dissolution of Telmisartan from the βCD complexes was rapid and higher when compared to Telmisartan pure drug and with different carriers. Hence
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