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Tarascó, Palomares Jordi. "Viabilidad de la sutura gastrica con adhesivos sinteticos de ultima generacion. Estudio experimental en ratas." Doctoral thesis, Universitat Autònoma de Barcelona, 2016. http://hdl.handle.net/10803/367446.
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Introducción: La eficacia clínica y la seguridad de los adhesivos biológicos y sintéticos en las suturas digestivas ya han sido evaluadas. Sin embargo, poco se sabe acerca de su papel en las suturas y anastomosis gástricas. Por otra parte, la utilización de nuevos tipos de adhesivos sintéticos a partir del n-butil-cianoacrilato no se han evaluado todavía.
Materiales y Métodos: Se realizó una gastrotomía de un centímetro en 24 ratas macho tipo Wistar, que se dividieron en función del tipo de método de sutura empleado: Sutura manual de 5/0 de seda discontínua versus sutura con adhesivo sintético tipo Histoacryl ™ flexible (n-butil-cianocrilato con “softener”) o tipo Histoacryl ™ Doble Componente (n-butil-cianoacrilato con “softener” y “hardener”). El objetivo de la valoración principal fue identificar las diferencias en la incidencia de fugas anastomóticas, la formación de adherencias y hallazgos microscópicos durante el proceso de cicatrización. Durante 8 semanas de seguimiento se estudiaron aspectos clínicos e histopatológicos, así como también perfiles hematológicos, iónicos y marcadores inflamatorios.
Resultados: No se observaron diferencias significativas entre los grupos cuando se compararon los aspectos clínicos, analíticos o histopatológicos evaluados. Sólo se evidenció una mayor tasa de incidencia de adherencias en el grupo Histoacryl doble componente en comparación con el grupo de sutura manual (p = 0,04). Nuestros resultados indican que ambos tipos de n-butil-cianoacrilato son materiales fiables para el cierre gástrico sin efectos secundarios significativos ni locales ni sistémicos.Background: Clinical effectiveness and safety of biological and synthetic adhesives in digestive closures have been evaluated. However, little is known about their role in gastric and anastomotic closures. Moreover, usefulness of novel types of synthetic adhesives as n-butyl-cyanoacrylate has not been assessed yet. Materials and Methods: One centimeter long gastrotomy was performed in 24 male Wistar rats which were divided depending on the type of closure method employed: manual USP 5/0 silk interrupted suture versus suture-less closure with Histoacryl™ flexible (n-butyl-cyanoacrylate with softener ) or Histoacryl™ Double Component (n-butyl-cyanoacrylate with softener and hardener ). The primary endpoint was to identify differences in the incidence of anastomotic leaks, adhesion formation and microscopic findings during the cicatrization process. During an 8-week follow-up clinical and histopathological aspects as well as hematologic, ionic and inflammatory markers were studied. Results: No differences among groups where found in any of the clinical, analytical or histopathological issues assessed except for a higher incidence rate of adhesions in the Histoacryl Double Component group when compared with hand-sewn suture group (p = 0.04). Our results indicate that both types of n-butyl-cyanoacrylate are reliable materials for gastric closure without significant neither local nor systemic side effects.
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Jackson, Remigius Kalasanz. "Circumaxillary Suture Strain during Midpalatal Suture Opening and Maxillary Protraction." The Ohio State University, 2012. http://rave.ohiolink.edu/etdc/view?acc_num=osu1331067181.
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Garcin, Camille. "Traitement chirurgical du strabisme par sutures ajustables." Bordeaux 2, 1992. http://www.theses.fr/1992BOR23076.
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Simões, Edson Azevedo. "Estudo comparativo entre sutura mecânica e manual em brônquio após pneumonectomia esquerda em cães (Canis familiaris): uma avaliação anatomo-patológica, paramétrica, radiológica e broncoscópica." Universidade de São Paulo, 2003. http://www.teses.usp.br/teses/disponiveis/10/10137/tde-07082007-114644/.
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Em cães, os estudos experimentais comparativos dos diferentes tipos de sutura para a síntese do brônquio principal são escassos, quando não ausentes nesta espécie. Além disso, existem possíveis complicações decorrentes da má cicatrização do brônquio. O objetivo deste estudo foi realizar um estudo experimental comparando-se sob o ponto de vista anatomo-patológico, paramétrico, radiológico e broncoscópico as suturas manual e mecânica em brônquio principal após pneumonectomia esquerda em cães. Foram utilizados 18 cães, sadios, machos e fêmeas, adultos, sem raça definida, pesando entre 9 e 27,5 kg. Os cães foram submetidos à intubação seletiva e toracotomia esquerda no 5º espaço intercostal, onde foi feita a pneumonectomia. Foram separados em 2 grupos de 9 cães, de acordo com o tipo de sutura empregada: Grupo A - sutura manual do coto brônquico principal esquerdo com pontos separados \"em 8\" com fio polipropileno 5-0; Grupo B - sutura mecânica do coto brônquico principal esquerdo com grampeador mecânico modelo TL-30 com grampos dispostos em fileira dupla. Cada grupo foi subdividido em 3 subgrupos de 3 animais, sendo estabelecido estudo temporal aos 7, 15 e 36 dias de pós-operatório, onde foi realizado a avaliação anatomo-patológica da cicatrização das suturas manual e mecânica, bem como, a avaliação paramétrica (antes da indução da anestesia, imediatamente após o final do ato cirúrgico, 48 horas, 7, 15 e 36 dias após o procedimento cirúrgico), avaliação radiológica ( 24 horas antes e com 7, 15 e 36 dias após o procedimento cirúrgico) e avaliação broncoscópica (após indução anestésica e com 7, 15 e 36 dias após o procedimento cirúrgico), consideradas importantes para avaliar possíveis complicações decorrentes deste tipo de procedimento cirúrgico. Estas avaliações foram realizadas de acordo com o estudo temporal nos diferentes subgrupos. A avaliação paramétrica foi realizada através da mensuração da temperatura, hematócrito, hemoglobina, freqüências cardíaca e respiratória. Na avaliação histopatológica foram avaliados qualitativamente e semi-quantitativamente a intensidade da inflamação, fibrose, vasos neoformados e a presença ou não de tecido de granulação, granuloma tipo corpo estranho e necrose. Os resultados encontrados foram analisados estatisticamente. Apesar das alterações dos índices paramétricos, todos os cães apresentaram evolução pós-operatória satisfatória. Com relação à análise histopatológica, ocorreu a formação de granuloma tipo corpo estranho no coto brônquico esquerdo em 88,9% dos cães submetidos à sutura manual e em nenhum dos cães submetidos à sutura mecânica. Houve ainda, diferença estatística significativa nos cães dos Grupos A e B em relação à intensidade da inflamação, sendo de maior intensidade nos cães submetidos à sutura manual. Os resultados obtidos mostraram não haver diferença estatística significativa nas avaliações radiográficas e broncoscópicas entre os Grupos A e B. Não foram observadas intercorrências no trans e pós-operatório. Concluiu-se que os 2 tipos de sutura promoveram cicatrização adequada do coto brônquico principal esquerdo, embora tenha ocorrido maior intensidade de inflamação e maior ocorrência de granuloma tipo corpo estranho nos cães submetidos à sutura manual, permitindo evolução paramétrica, radiológica, broncoscópica pós-operatória satisfatória e sem diferença nos cães dos Grupos A e B.In dogs, comparative experimental studies of the different types of sutures for the synthesis of the main bronchus are scarce, when not all available in this species. Furthermore, there are possible complications due to the poor healing of the bronchus. The objective of this study was to perform an experimental study to be compared under the pathological-anatomic, parametric, radiological and bronchoscopic point of views, the manual and mechanical sutures in the main bronchus after left pneumonectomy in dogs. Eighteen adult mongrel, healthy dogs, both male and female, were utilized weighing from 9 to 27.5 kg. The dogs were submitted to a selective intubation and left thorax incision in the 5 th intercostal space where a pneumonectomy was performed. Were separated into 2 groups of 9 dogs according to the type of suture employed: Group A - a manual suture of the main left bronchial stump with separate stitches \"in 8\" with polypropylene 5-O; Group B - a mechanical suture of main left bronchial stump with a mechanical stapler, model TL-30 arranged in a double file. Each group was subdivided into 3 subgroups of 3 animals and a temporal postoperative study was established at 7, 15 and 36 days where an pathological-anatomic evaluation was made on the healing of the manual and mechanical sutures as well as a parametric evaluation (before the induction of anesthesia, immediately after the final surgical act, 48 hours, 7, 15 and 36 days after the surgical procedure), radiological evaluation (24 hours before and with 7, 15 and 36 days after the surgical procedure), and bronchoscopic evaluation (after the induction of anesthesia and with, 7, 15 and 36 days after the surgical procedure), considered important to evaluate possible complications due to this type of surgical procedure. These evaluations were made according to the temporal study in the subgroups. The parametric evaluation was made through the mensuration of temperature, hematocrit, hemoglobin, heart and respiratory rate. During the histopathological evaluation, the intensity of inflammation, fibrosis, neoformed vessels, and the presence or absence of granulation tissue, foreign body reaction and necrosis were evaluated qualitatively and semi-quantitatively. The results found were analyzed statistically. Although the difference observed in the parametric evaluations, all the dogs showed good recovery postoperative. Regarding the histopathologic analysis, foreign body reaction occured in the left bronchial stump in 88,9% of the dogs submitted to a manual suture and in none of the dogs submitted to a mechanical suture. There is still, significant statistical difference in the dogs in Groups A and B in relation to the intensity of the inflammation, the greatest intensity being in the dogs submitted to the manual suture. The results obtained showed that there was no significant statistical difference in the radiographic and bronchoscopic evaluations between Groups A and B. No intercurrences were observed in the trans and postoperative period. It is concluded that both types of sutures brought an adequate healing of the main left bronchial stump, although there was a greater intensity of inflammation and a greater occurence of foreign body reaction in the dogs submitted to the manual suture, permitting satisfactory parametric, radiological and bronchoscopic postoperative evolution and there is no difference in all of the dogs in Groups A and B.
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Corrêa, Rodrigo Romero. "Propriedades mecânicas de dois padrões de sutura e dois tipos de fios aplicados às tenorrafias de equinos." Universidade de São Paulo, 2012. http://www.teses.usp.br/teses/disponiveis/10/10137/tde-24092012-154147/.
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As lesões traumáticas do membros que resultam em secções tendíneas são problemas comuns na clínica equina. Estas lesões podem ser tratadas de forma conservativa ou cirúrgica. Diversas complicações tem sido associadas às técnicas cirúrgicas, como ruptura do fio de sutura, ruptura do coto tendíneo suturado, infecções da ferida, entre outros. O objetivo do presente trabalho foi avaliar biomecanicamente a combinação entre os padrões de sutura locking loop duplo e locking loop simples com sutura de epitendão, com os fios de sutura polipropileno e poliglactina 910, ambos de número 2, visando estipular a melhor combinação entre as variáveis quando aplicadas ao tendão flexor digital profundo de equinos. Os corpos de prova foram submetidos a ensaios mecânicos de tração, onde determinaram-se valores de força mínima, força máxima e pico de força durante o afastamento de 3 milímetros entre os cotos suturados, além do afastamento observado entre os cotos durante o pico máximo de força. Quando avaliada a força máxima, observaram-se maiores valores (p0,05) nos grupos onde foi utilizado o padrão locking loop simples com sutura de epitendão, e também quando a sutura foi realizada com polipropileno. Para a força mínima, o padrão simples também se mostrou superior, não havendo diferença significativa quando variaram-se os fios de sutura. Quando avaliado o pico de força, as suturas duplas foram superiores, não havendo diferença estatística quando comparadas com a sutura simples realizada com polipropileno. Os padrões duplos permitiram maior afastamento que os padrões simples com sutura de epitendão. O padrão locking loop simples, com sutura de epitendão, atinge maiores valores de força enquanto o afastamento é de até 3 milímetros. Quando realizado com polipropileno, este padrão suporta maior carga do que quando realizado com poliglactina.The traumatic lesions of the limbs that result in tendon sections are common problems in equine medicine. These lesions can be treated with clinical or surgical procedures. Several complications, as rupture of the suture material, rupture of the tendon extremity and wound infection have been associated with the technique. The objective of this study was evaluate biomechanically the locking loop suture and the locking loop with epitendon suture, when performed with polypropylene and polyglactin 910 suture material, number 2, looking for the best combination between the variables when applied to equine deep digital flexor tendon. The specimens was submitted to a strain test. Values of minimum strength, maximum strength and force peak were measured during 3 millimeters of separation between the tendon extremities, and the gap was observed between the tendon extremities during the maximum peak force. During maximum strength evaluation, the higher values (p0,05) were observed in groups which were used simple locking loop pattern associated with epitendon suture, and also when the suture was performed with polypropylene. For the minimum strength, the simple pattern was also better, showing no significant difference between the types of suture material. When the peak force was measured, the double sutures were better, and there was no statistic variation when compared with the suture performed with polypropilene in a simple pattern. The double patterns allowed higher separation than the simple patterns associated with epitendon suture. The simple locking loop pattern, with epitendon suture, reaches higher values of strength when there is 3 millimeters of separation. When performed with polypropylene, this pattern supports higher load than when performed with polyglactin.
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Premaraj, Sundaralingam. "Studies in cranial suture biology." Columbus, Ohio : Ohio State University, 2006. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1155140476.
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Vende, Dominique. "Le traitement chirurgical de la diplopie : l'apport de la chirurgie reglable." Toulouse 3, 1989. http://www.theses.fr/1989TOU31067.
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Philip, Ragnartz, and Axel Staffanson. "Produktutveckling av medicinteknisk produkt, Suture passer." Thesis, Mälardalens högskola, Akademin för innovation, design och teknik, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:mdh:diva-33170.
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The following report has been prepared based upon an assignment given by the company, Ortopedic Care Scandinavia AB. The paper is an exam on basic level, 15 credit points at higher level education within product development. Ortopedic Care Scandinavia AB is working with product development of medical technology products. What makes the corporate unique is the fact that the development is based upon problems encountered by surgeons in their daily work. Suggestions for improvement in technology are given directly by the end users. This paper is based upon such problems. Product development was made on the medical instrument called, suture passer. The instrument is used in endoscopic surgery of the rotator cuff. The cuff is a group of four muscles (and their respective tendons) that stabilize the shoulder. In case of an accident, mostly sport related, these muscles can loosen from the bone. In surgery a suture passer is then used to penetrate the injured tendon with a needle with an attached suture. The passer creates a loop of suture that can be used to attach the damaged tendon. The report is based upon the following problem formulations: The needle has an inconvenient edge that can damage the muscle. The strength of the suture thread is deteriorated by the design of the needle. The suture thread has been known to snap when the surgeon apply to much pressure when tying. If the patient is suffering from subacromial impingement the jaw of the instrument can appear to be clumsy and hard to open. The jaw has sharp teeth which have been known to get stuck in the tendon. The surgeon must then perform an uncontrolled movement which might damage the tendon. The jaw limits the surgeons’ choice of thickness of the suture thread. The thickness of the needle used in the suture passer is limited to one size. The purpose of the project is to develop a new concept that minimizes the risk for the patient and at the same time the concept should facilitate the work of the surgeon. The concept should meet the set requirements and be presented in the form of renderings of CAD-models and drawings. To achieve this process the instrument uses four different components. The needle, the jaw, the handle and an attachment between the needle and the handle. Under heading 5, the generating process, each component presents to together with arguments of its design. The instrument consist of 25 components that are all developed from the ground up. The result should be viewed as a thorough concept that can be used for further development. It is recommended that the next step should be an investigation about material choice. When the material is specified a prototype should be manufacture and then used for testing.
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Du, Trevou Claire. "Suture and sante : a placemaking procedure." Diss., University of Pretoria, 2014. http://hdl.handle.net/2263/45277.
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The post-apartheid repetition and insertion of an unchanged standard clinic design across South Africa, has resulted in a number of urban and design problems stemming from the architecture of the clinics and their inability to adapt. Designed before the resurgence of the Tuberculosis epidemic, the
facilities were not designed for optimal ventilation or air-borne infection
prevention . The current healthcare facilities cannot support the
ever-increasing urban population, and as a result, patients are forced to wait for long hours before being attended to, in poorly ventilated, unstimulating
spaces.
Emanating from an understanding of the relationship between architecture, health and the transmission of disease, the dissertation endeavours to create a new healthcare facility that remedies these problems through design.
The dissertation identifies Alaska, an informal settlement, as an appropriate site in need of and with a population size to support a new public
healthcare facility.
Recognising the risks of blind top-down provision of buildings into informal settlements, the dissertation explores the power of a collaborative approach towards design. The design process engages the community in a series of
participatory exercises in order to discover and enable grass-roots
knowledge and innovation, and to instill a sense of ownership and
responsibility for the intervention, after construction is complete.
The dissertation studies the traditional healthcare practitioners within the
settlement, for spatial clues and an alternate approach to the provision and architecture of healthcare. The Salutogenic (the healthy pole of the health- disease
continuum) approach of the traditional healers is merged with the pathogenic design sensibilities of typical western facilities, in order to create a facility which not only focuses on curing disease, but also on instilling
preventative habits within the community.
The intervention intention to be reflective of and responsive to the dynamic context of Alaska, is realised through the spatial and design intelligences of a top-down provider enabling the innovation and local knowledge of bottom-up approaches through a collaborative design process.
The intetnion is expressed through the inclusion and manipulation of local building materials and techniques.Dissertation (MArch(Prof))--University of Pretoria, 2014.
Architecture
MArch(Prof)
Unrestricted
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Loh, Aeseun. "Controlled release of drugs from surgical suture." Thesis, Massachusetts Institute of Technology, 1987. http://hdl.handle.net/1721.1/14960.
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Thesis (B.S.)--Massachusetts Institute of Technology, Dept. of Materials Science and Engineering, 1987.MICROFICHE COPY AVAILABLE IN ARCHIVES AND SCIENCE.
Bibliography: leaf 39.
by Aeseun Loh.
B.S.
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Vokrri, Lulzim. "Etude expérimentale des anastomoses vasculaires sans suture." Thesis, Université Grenoble Alpes (ComUE), 2017. http://www.theses.fr/2017GREAS007.
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Saia, Paula Simone. "Sistema ceratométrico de apoio a suturas na córnea." Universidade de São Paulo, 2007. http://www.teses.usp.br/teses/disponiveis/18/18133/tde-26032008-153951/.
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Um sistema para auxílio à cirurgias oftálmicas foi desenvolvido com o objetivo de se minimizar o astigmatismo induzido devido ao formato irregular da córnea pelo ato de sutura. O sistema projeta 48 pontos de luz no filme lacrimal da córnea, provenientes de LEDs, dispostos num diâmetro precisamente circular. O deslocamento, a dimensão e a deformação da imagem refletida destes pontos luminosos são analisados proporcionando a ceratometria e a circularidade da sutura. O intervalo de medidas do sistema é de 32D - 55D (astigmatismos até 23D podem ser medidos) e um sistema para calibração do sistema foi projetado para manter o sistema calibrado. Esferas de aço de precisão foram submetidas ao sistema e uma correlação de 99% entre as medidas obtidas e os valores dos fabricantes foi obtida. O sistema foi testado em 13 voluntários para avaliação de sua aplicabilidade clínica e comparado a um ceratômetro comercial Topcon OM-4. Os fatores de correlação entre o sistema desenvolvido e o Topcon OM-4, para o astigmatismo, foi de \'R POT.2\' = 0,92, e em relação ao eixo, o fator é \'R POT.2\' = 0,99. O sistema indica que o cirurgião deve obter uma circularidade \'> OU =\' 98% para que astigmatismos acima de 3D não sejam induzidos na sutura.A system for ophthalmic surgery support has been developed in order to minimize the residual astigmatism due to the induced irregular shape of the cornea by corneal suture. The system projects 48 light spots, from LEDs, displayed in a precise circle at the lachrymal film of the examined cornea. The displacement, the size and deformation of the reflected image of these light spots are analyzed providing the keratometry and the circularity of the suture. Measurements in the range of 32D - 55D (up to 23D of astigmatism are possible to be obtained) and a self-calibration system has been designed in order to keep the system calibrated. Steel precision spheres have been submitted to the system and the results show 99% of correlation with the fabricant\'s nominal values. The system has been tested in 13 persons in order to evaluate its clinical applicability and has been compared to a commercial keratometer Topcon OM-4. The correlation factors are 0,92 for the astigmatism and 0.99 for the associated axis. The system indicates that the surgeon should achieve circularity \'> OR =\' 98% in order to do not induce astigmatisms over 3D.
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Chaves, Junior Nilson [UNIFESP]. "Efeitos da elevação da pressão intra-abdominal e de seu tempo de ação na cicatrização de suturas mecânicas no estômago de cães." Universidade Federal de São Paulo (UNIFESP), 2006. http://repositorio.unifesp.br/handle/11600/21472.
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Previous issue date: 2006Objetivo: Estudar a fase inicial da cicatrização de uma sutura gástrica confeccionada com grampeador linear cortante, submetida ao aumento de pressão intra-abdominal por pneumoperitônio entre 12 e 14 mmHg, durante sessenta e cento e vinte minutos, comparando-as com a mesma sutura mantida sob pressão atmosférica Métodos: Utilizou-se 30 cães distribuídos em 3 grupos de 10 animais: Grupo I, denominado de controle (sutura gástrica linear cortante), Grupo II (sutura gástrica linear cortante) e aumento da pressão intra-abdominal logo após a sutura por 60 minutos e Grupo III (sutura linear cortante) e aumento da pressão intra–abdominal logo após a sutura por 120 minutos. Todos os cães foram mantidos sob anestesia geral por 120 minutos após a sutura comum aos 3 grupos. Decorridos 7 dias de pós– operatório, avaliou-se os parâmetros macroscópicos do estômago e microscópicos de fragmentos gástricos junto a linha de sutura. Resultados: Na observação macroscópica dos grupos (n=30), não se evidenciou deiscências, fístulas ou abscessos, porém houve presença de aderências do omento em torno dessas suturas em 100% dos animais dos grupos II e III (n=20), mostrando significância estatística quando comparados com aqueles do grupo I (p=0,008*). Os estudos histopatológicos mostraram que os animais do grupo controle (n=10) tiveram todas as fases da cicatrização se desenvolvendo normalmente no final do 7° dia, e quando se comparou os resultados com aqueles animais que estiveram submetidos ao aumento da pressão intra–abdominal, grupos II e III (n=20), notou-se alterações com significância estatística nos testes não paramétricos empregados de parâmetros na fase aguda da cicatrização, tais como: migração de fibroblastos (p=0,011*), edema (p<0,001*) e congestão (p=0,011*), que interferiram na reepitelização do tecido (p<0,001*) portanto, no processo final de cicatrização. Conclusões: As suturas se desenvolveram em estágios evolutivos diferentes, em cada grupo de animais, e aquelas submetidas ao aumento de pressão intra-abdominal tiveram retardo no processo normal de cicatrização. Esses fenômenos foram mais evidentes no grupo que permaneceu por mais tempo sob ação do pneumoperitônio.
Purpose: To assess the initial healing after placing a gastric suture with a linear cutting stapler and creating pneumoperitoneum (12-14 mmHg) for 60 minutes or 120 minutes, and compare it with the healing after placing a suture under normal pressure. Methods: A total of 30 dogs were divided into three groups of 10 animals each: Group I (control group – mechanical suture), Group II (mechanical suture and increased intra-abdominal pressure in the first 60 minutes) and Group III (mechanical suture and increased intraabdominal pressure in the first 120 minutes). All dogs were maintained under general anesthesia for two hours after suturing. Seven days after surgery, the area around the mechanical suture was macroscopically and microscopically examined. Results: The macroscopic examination of the samples (n = 30) did not show dehiscence, fistula or abscess. Adhesions between the omentum and the suture were observed in all animals of groups II and III (n = 20), which were significantly different from group I (p = 0.008*). The histopathological analysis showed normal healing up to day 7 in the control animals (n = 10). When these results were compared with those of groups II and III (n = 20), non-parametric tests revealed that there was a significant difference with regard to certain parameters of the early stages of healing, such as fibroblast migration (p = 0.011*), edema (p < 0.001*) and congestion (p = 0.011*). These alterations affected reepithelization (p < 0.001*), and consequently the late stages of healing. Conclusions: Each group showed different healing stages, and the healing process was delayed in the groups submitted to increased pressure. This was more pronounced in the group submitted to increased pressure for longer.
BV UNIFESP: Teses e dissertações
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Vroman, Maura Josephine. "Differential growth of the frontonasal suture in rabbits." Thesis, University of Iowa, 2010. https://ir.uiowa.edu/etd/615.
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The purpose of this study was to substantiate previous claims that differential growth across the frontonasal suture occurs and if this differential growth pattern is caused by an increased mitotic rate of the nasal bone.
Two six week old New Zealand White Rabbits were given calcein 20mg/kg IA, demeclocycline 20mg/kg IA, and BrdU 40mg/kg IA on Days 1, 11, and 14, respectively. The animals were euthanized using Ketamine 31.6mg/kg IM and Pentobarbital 100mg/kg IV. The frontonasal suture was removed from the rabbit and divided into hemisections. The right hemisection was histologically processed using standard calcified methods which were modified and used for smaller bone sections at the Comparative Orthopaedic Research Laboratory, School of Veterinary Medicine, University of Wisconsin. The left hemisection was reserved for BrdU staining at the Central Microscopy Research Facility, University of Iowa. The resultant slides were imaged and photographed using an Olympus BX-40 microscope and measured using ImageJ software (NIH). Means and standard deviations were calculated for interlabel distance and mineral apposition rate (MAR).
All frontonasal suture sites demonstrated double fluorochrome labeling. Samples F2-2 and M2-1 demonstrated the predicted differential growth pattern. Samples F2-1 and M2-2 did not. No suture sites demonstrated positive staining for BrdU. Although the sample size was small (n=2), this may demononstrate a trend toward differential growth of the suture.
Due to the small sample size, the labeling protocol used in this study provided limited quantitative data. Although two sections did not demonstrate more bone deposition or faster mineral apposition rate of the nasal bone, it is important to consider that these sections were of poorer quality when compared to the other sections. Higher quality sections with clear, measurable margins showed a difference between frontal and nasal bone growth in both morphology and mineral apposition rate.
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Wang, Weiliang, and 王維亮. "Amphibolites of the Bangong-Nujiang suture zone, Tibet." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2008. http://hub.hku.hk/bib/B41897237.
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Lenoir, Hugues. "Contradictions sociales et formation : entre rupture et suture." Lyon 2, 1998. http://theses.univ-lyon2.fr/sdx/theses/lyon2/1998/hlenoir.
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Ce travail repose sur l'hypothèse que depuis les débats fondateurs sur l'éducation des adultes, la formation apparaît à la fois comme un outil de cohésion sociale visant à réaliser la suture entre le Capital et le Travail et/ou comme un instrument de dissociation sociale tendant à la rupture entre deux pôles inconciliables. Par l'éducation des adultes se situe au centre d'un système de tensions, au coeur d'une dialectique du social où se retrouve une double fonctionnalité (rupture-suture) à tous les niveaux et dans toutes les pratiques de formation mais à des échelles différentes et au service d'enjeux plus ou moins fondamentaux. Pour conduire cette thèse, au-delà d'une approche historique développée dans l'introduction, nous avons utilisé des recherches et des réflexions qui permettent de resituer la formation dans une tension continue, quelquefois, voire souvent, contradictoire entre développement des organisations et épanouissement des individus. Ils positionnent enfin la formation dans une problématique sociale plus large, en la situant au carrefour des évolutions de l'appareil de production, de la gestion des ressources humaines et de son utilisation comme outil de maintien de la cohésion et de la paix sociales. Ce travail s'organise en quatre parties où ont été repris des matériaux qui permettent de repérer des continuités et des ruptures-sutures dans la formation des adultes. La première partie est structurée autour de contributions centrées sur le rôle de la formation dans les organisations de travail privées ou publiques. La deuxième partie est un ensemble de réflexions sur la place, le statut et le développement de la formation permanente dans les universités. La troisième partie se focalise sur l'activité de formateur (la pédagogie") et en souligne les contradictions et les limites. La quatrième partie s'intéresse au métier de formateur, à ses évolutions et aux formations qui y préparent. Elle illustre en s'impliquant dans le débat "éthique" la rupture qui s'y opère et que certains essaient d'analyser et de colmater. Sans prétendre donner un mode de compréhension général de la formation des adultes, cette thèse permet d'en éclairer certains aspects, de souligner quelques points en débat et de proposer une clé dans le cadre de la contradiction rupture-sutureThis research is based on the hypothesis that, ever since the founding debates on adult education, such training serves simultaneously as a tool for social cohesion, meant to accomplish the suturing of Capital and Work, and/or as an instrument of social dissociation, tending to engender a rupture between two irreconcilable poles. By consequence, adult education finds itself at the center of a system of tensions, at the heart of a social dialectic, where a dual functioning is apprant at all levels and in all training practices, though on different scales and serving ends which are more or less fundamental. To conduct this thesis, beyond the historical approach which is developed in the introduction, we have used research and reflections allowing us to resituate the training process in a continuum of tension, which is sometimes, or rather frequently, contradictory to the growth and development of organizations and/or that of individuals. These studies reposition the problem of adult education in a larger social context, placing it at the meeting point between the evolution of the production apparatus, and human resource management, in particular this training's use as a tool for maintaining social cohesion and peace. The research is organized in four parts, based on material allowing us to detect the continuities, and the rupture-suture in adult education. The first part is structured around contributions which discuss the role such programs play in private or state work organisations. The second part is a collection of reflections on the position, the status and the development of continuing education in universities. The third part focuses on the educator's activity (the pedagogy"), and highlights its contradictions as well as its limitations. The fourth part is concerned with the profession of educator, its evolutions, and the training processes used in its preparation. Through implication in the ethical debate, this final section illustrates the rupture operating within the profession, and which some attempt to analyse and reconcile. Without intending to offer an exhaustive method of comprehension concerning adult education, this thesis allows us to clarify certain aspects of the subject, to emphasize several points within the surrounding debate, and to propose a key to its understanding, in the context of the rupture-suture contradiction
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Nee, Matteo. "Suture-Type Fiducial Marker Oncology Market Entry Strategy." Case Western Reserve University School of Graduate Studies / OhioLINK, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=case1535378317004445.
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Wang, Weiliang. "Amphibolites of the Bangong-Nujiang suture zone, Tibet." Click to view the E-thesis via HKUTO, 2008. http://sunzi.lib.hku.hk/hkuto/record/B41897237.
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Lenoir, Hugues Meirieu Philippe. "Contradictions sociales et formation entre rupture et suture /." [S.l.] : [s.n.], 1998. http://theses.univ-lyon2.fr/sdx/theses/lyon2/1998/hlenoir.
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Lok, Adrian. "Quantifying the effects of mechanical vibration on the volume of the midpalatal suture." Thesis, The University of Sydney, 2018. http://hdl.handle.net/2123/20890.
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Introduction Whole body high-frequency low-magnitude vibration (HFLMV) is routinely used in the medical field to improve bone quality in children. For this treatment, vibration is induced during a period when growth of the midpalatal suture is heavily influenced by the external environment. The midpalatal suture acts as a growth site responding to external signals stimulating deposition of bone on the sutural edges, facilitating transverse maxillary growth. Any additional mechanical strain such as HFLMV could modify the rate of bone remodelling at the interface of the two maxillary bones and affect natural growth. Objectives To evaluate the effects of HFLMV on the volume of the midpalatal suture (MPS) of rats. Materials and methods This study consisted of forty-two, five-week-old Fisher Strain male rats which were previously used in a study investigating the effects of vibration on hypofunctional teeth. The rats were randomly allocated into Vibration and Non-vibration groups. In the vibration groups, HFLMV was induced through whole body vibration platforms. The rats were kept in their cages and placed two at a time on the vibrating platform set at a magnitude of 0.3g and frequency of 30Hz. This stimulus was applied for 20 minutes per day, five days per week for a total of 30 days. The MPS was analysed as two separate volumes of interest in order to avoid the regions complicated by the pre-maxillomaxillary and palatomaxillary sutures. Three-dimensional micro-computed tomography (micro-CT) was used to quantify the volumes of the MPS. The measured volumes of the mid-palatal suture were adjusted by the length of the rat heads and statistical analysis was conducted. Results There was no statistically significant difference in the volumes of the MPS in any region between the Vibration and Non-vibration groups. Conclusion The findings of this 30-day animal study indicate that HFLMV applied through whole body vibration platform does not affect the volume of the MPS of rats.
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GRAPPIN, MICHEL. "Astigmatisme induit et sutures dans les keratoplasties transfixiantes." Aix-Marseille 2, 1988. http://www.theses.fr/1988AIX20249.
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Hotzman, Jennifer Lane. "Dietary consistency and sutural morphology the complexity of the mid-palatal suture in Procolobus badius and Colobus polykomos /." [Gainesville, Fla.] : University of Florida, 2004. http://purl.fcla.edu/fcla/etd/UFE0006440.
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Nguyen, Ngoc Thông. "Evolution de la suture palatine médiane au cours de la vie." Paris 11, 2009. http://www.theses.fr/2009PA113001.
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La suture palatine médiane provient, embryologiquement d'une part du bourgeon médian qui va donner notamment le palais primaire (5ème semaine) et d'autre part des processus palatins latéraux, issus de la face profonde des bourgeons maxillaires qui vont réaliser le palais secondaire (6ème - 12ème semaine). Ainsi, les zones de fusion, de type synfibrose, des différents éléments vont donner la suture palatine médiane. L'enjeu de ce travail est de connaître l'évolution de la synfibrose de la suture palatine médiane. L'étude est composée de deux parties : radiologique, surtout, examens de scanners des sinus maxillaires chez l'enfant et l'adulte et histologique, étude de pièces anatomiques de palais chez le foetus, l'embryon, l'adulte et l'animal. Les résultats montrent qu'il n'existe pas d'âge de fermeture complète de la suture palatine médiane. Egalement, ils révèlent que les palais primaire et secondaire évoluent séparément : selon l'axe antéropostérieur, le secondaire se ferme d'avant en arrière et généralement après la fermeture du primaire et selon l'axe vertical, le palais primaire se ferme de bas en haut tandis que le palais secondaire de haut en bas. Il est difficile de transposer ces résultats en orthopédie dentofaciale puisque la disjonction de la suture palatine médiane est essentiellement orthodontique et rarement chirurgicale (après l'âge de 14-16 ans). Mais, deux explications peuvent être avancées : l'existence au niveau de la suture d'un tissu osseux "" jeune et lâche""permettant une disjonction orthodontique ou ""âgé et dense"" obligeant un acte chirurgical, plus ou moins associée à une absence de fermeture de la suture non visible radiologiquement. Néanmoins, un scanner peut être utile en cas de disjonction chirurgicale afin de guider le chirurgien sur la profondeur de l'ostéotomieIn embryology, the mid palatal suture comes from the median bud which will give, including, the primary palate (5th week) and the lateral palatine process, issued from the deep surface of the maxillary buds which will create the secondary palate (6th ?€? 12th week). Thus, the areas of mergers, type synfibrosis, different elements will give the mid palatal suture. The challenge of this study is to know the development of the synfibrosis of this suture. The work is composed of two parts : radiologic, especially, reviews of CT scanners of maxillary sinus in children and adults and histologic, study anatomical parts of palates in the fetus, embryo, adult and animal. The results show that there is no age for a complete closure of the mid palatal suture. Also, they show that the primary and secondary palates evolve separately : for anterior-posterior axis, the secondary closes from front to back and usually after the closure of the primary and for vertical axis, the primary palate closes from bottom to top, whereas the secondary palate, from top to bottom. It is difficult to translate these results in dentofacial orthopedic since the disjunction is mainly orthodontic and rarely surgical (after the age of 14-16). But, two explications can be explained : the existence at the suture, a bone tissue "young and low" which allows a orthodontic separation or "old and dense" requiring surgical procedure, more or less with a lack closure of the suture not visible radioactively. Nevertheless, a scanner can be useful in a surgical disjunction to guide the surgeon on the depth of the osteotomy
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D'Amico, Laura Lee. "The effects a novel extracapsular suture technique (lateral extracapsular suture system or LESSa) on the kinematics of the cranial cruciate deficient stifle." Thesis, Virginia Tech, 2013. http://hdl.handle.net/10919/50571.
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Objective: To evaluate the relative position of the femur and tibia in cranial cruciate ligament (CCL) intact stifles, CCL deficient stifles, and stifles following a novel extracapsular procedure (lateral extracapsular suture system or LESSa) under load at specific joint angles.Study Design: In vitro biomechanical study.
Methods: Twenty pelvic limbs from 11 dogs were used to evaluate the relative position of the femur and tibia between 3 stifle conditions (CCL intact, CCL deficient, and LESSa treated) at a load of 30 % and stifle angles of 125", 135", and 145" using electromagnetic tracking sensors.
Results: Cranial cruciate ligament deficient stifles had significantly greater (p <0.0001) cranial displacement and internal rotation of the tibia relative to the femur than CCL intact stifles or LESSa treated stifles at all stifle angles. Cranial displacement of the tibia relative to the femur for CCL intact and LESSa treated were not significantly different from one another at stifle angles of 125", but were significantly different at stifle angles of 135" (p = 0.0182) and 145" (p = 0.0012). There was no significant difference in internal rotation of the tibia relative to the femur between CCL intact and LESSa treated stifles at any of the stifle angles.
Conclusion: LESSa effectively decreases cranial tibial displacement and eliminates internal rotation of the tibia relative
Master of Science
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Archambault, Lucie. "Atelier de couture, atelier de suture, thank you for--." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape4/PQDD_0020/MQ55734.pdf.
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Guébert, Christophe. "Suture en chirurgie virtuelle : simulation interactive et modèles hétérogènes." Phd thesis, Université des Sciences et Technologie de Lille - Lille I, 2010. http://tel.archives-ouvertes.fr/tel-00561061.
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La médecine a été une grande motivation dans la recherche en informatique, et nous pensons que la simulation de procédures médicales sera un élément majeur de la médecine du 21e siècle. Pour ces applications, la simulation physique doit être interactive et proposer un comportement et un rendu visuel des objets simulés qui soient réalistes tout en faisant avec un temps de calcul limité. Dans ce travail, nous nous sommes intéressés à la simulation du geste chirurgical de la suture, faisant interagir des modèles hétérogènes (rigides, déformables 1D et 3D) dans la reproduction d'un geste complexe. Nous proposons de modéliser ces interactions par des contraintes de complémentarité, avec une méthode générique et une résolution indépendante des types de contraintes utilisées. Cette approche a permis la mise au point de contraintes spécifiques pour créer des modèles d'interaction nouveaux. Ces contraintes ont permis une simulation complète de l'insertion d'aiguille, validée par les mesures expérimentales des travaux antérieurs, qui suit les lois physiques et s'adapte à la manipulation de l'utilisateur. Enfin, une simulation interactive très réaliste a été réalisée pour l'entraînement au geste de suture dans le cadre d'opérations laparoscopiques.
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Hughes, Christopher. "A finite element modelling strategy for suture anchor devices." Thesis, Brunel University, 2014. http://bura.brunel.ac.uk/handle/2438/11553.
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Suture or bone anchors are used to reattach a tendon or ligament after it has been torn away from the bone. Anchors provide secure attachments to bone during trauma or reconstructive surgery, holding the ligament or tendon in place and potentially allowing greater mobility during recovery. Computer modelling techniques are used to investigate both established bone anchor technology, such as threaded implants, and emerging technologies such as cement augmentation or sonic-fusion. Sonic fusion is an ultrasound-assisted anchoring method which has recently been introduced in low load maxillofacial applications, and is expected to be used in other low load applications such as hallux valgus alignment procedures and suture attachment. Threaded anchors were examined using two Finite Element (FE) models of human cancellous bone, representing both “normal” and “weaker” bone. Simulation and analysis revealed the critical nature of modelling the microstructure of bone. Changing the direction of loading in the model leads to significant changes in the response of the construct, and this cannot be represented in continuum models, or in physical models using artificial cancellous bone. Rapid prototyping (RP) using 3d printing was used for validation of the FE models. While this method has previously been implemented to create physical bone models, testing an assembly model and comparing it to FE results for inclined loading had not been attempted. RP models were created of the threaded anchor in both “normal” and “weaker” bone, and a sonic fusion model in the normal bone was also created. These models were then subjected to mechanical testing. Results produced from the simulation correlated with the physical results. The importance of a cortical layer was re-confirmed. At the apparent densities simulated, engagement with the cortical layer increases pull-out force dramatically. Engaging the anchor even with a thin cortical layer can produce a significant improvement to pull-out strength. Novel sonic fusion FE models were created from a CT scan of animal bone, and the geometry for both the sonic-fusion pin and bone were taken from the CT scan. Computer generated geometry was used to build pin concepts of varying shapes. It was shown that if good engagement is made with bone, as in the case of all of the concepts created, then sonic fusion can produce a good holding power - comparable with that of a threaded anchor. The results showed that sonic-fusion requires less drill penetration into the bone, meaning less of the inherent bone structure is removed – vital for patients with poor bone quality. Bone cement models were investigated. Bone augmentation models were created, and the addition of cement demonstrated an improvement in anchor holding power. The research showed that there are benefits to using FEA as a tool to evaluate the mechanical aspects of cement distribution. The results proved the hypothesis that augmentation will likely increase the holding power of anchor, and its distribution will affect pull-out significantly. This work has created a method for modelling and evaluating both established and novel bone anchor technology in CT bone geometry, a procedure which could be expanded to other bone implants. It has been validated using the innovative approach of rapid prototyping.
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Ekblom, Johanna. "Monofilt eller multifilt suturmaterial : Vad är bäst för den nyblivna mamman?" Thesis, Uppsala University, Department of Women's and Children's Health, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-110566.
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Syfte
Syftet med studien var att undersöka om det fanns skillnader mellan kvinnor som blivit suturerade med ett snabbabsorberande monofilt suturmaterial, Caprosyn® och ett multifilt suturmaterial, Polysorb® då det gällde kvinnans uppfattning om hur bristningen läkte åtta veckor postpartum.
Urval
Ett konsekutivt randomiserat urval. Fyrahundratvå kvinnor som fått en bristning vid förlossningen randomiserades till att sutureras med antingen Caprosyn® eller Polysorb®. Den slutgiltiga svarsfrekvensen var 67 %, det största bortfallet var på förlossningsavdelningen.
Metod
En experimentell kvantitativ studie. Två enkäter användes i studien, en som barnmorskan besvarade direkt efter förlossningen om bristningens art samt en till de medverkande kvinnorna åtta veckor postpartum.
Resultat
Inga skillnader fanns mellan suturmaterialen då det gäller kvinnornas smärta i underlivet, obehag i underlivet, återupptagande av sexualliv, samlagssmärta, amning eller hur många kvinnor som sökt sjukvård samt varför de sökt sjukvård åtta veckor postpartum. Fler positiva kommentarer gavs av barnmorskorna om Polysorb® än om Caprosyn®. Om kvinnan ammade delvis och hade samlagssmärta var denna smärta större än för de kvinnor som ammade helt. Ju lägre kvinnan skattade sin förlossningsupplevelse desto mer smärta hade kvinnan vid samlag åtta veckor postpartum.
Slutsats
De två studerade suturmaterialen skiljer sig inte åt enligt de deltagande kvinnornas upplevelse åtta veckor efter förlossningen. Däremot fanns ett samband mellan smärta i underlivet och upplevelse av förlossningen samt mellan hur mycket kvinnan ammade och samlagssmärta. Sammanfattningsvis kan barnmorskor inom förlossningsvården använda sig av båda materialen vid suturering av bristningar efter förlossning utan att det påverkar kvinnans hälsa negativt.
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Sugo, Arthur Tomotaka. "Comparação de dois tipos de sutura da musculatura abdutora na marcha de pacientes submetidos à artroplastia total primária do quadril pela via lateral direta." Universidade de São Paulo, 2017. http://www.teses.usp.br/teses/disponiveis/17/17142/tde-02042018-105424/.
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A evolução da artroplastia total do quadril (ATQ) tem sido auxiliada por informações geradas a partir de estudos de análise de marcha, sendo possível avaliar objetivamente a função do quadril após a substituição total da articulação. Seus resultados podem ser utilizados para estudar fatores que poderiam influenciar no resultado da cirurgia, como tipos de acesso, implantes e reabilitação pós-operatória. A abordagem lateral direita, descrita por Hardinge em 1982 apresenta uma excelente exposição à porção anterior do quadril e do fêmur proximal, porém com uma potencial desvantagem que é a secção da parte anterior do músculo glúteo médio do trocânter maior. Apesar da sua reinserção adequada, pode haver insuficiência abdutora após ATQ, em decorrência da avulsão pós-operatória desta sutura, resultando em fraqueza abdutora, comprometendo a marcha. O objetivo do estudo foi comparar parâmetros cinemáticos da marcha após ATQ primária pela via de acesso lateral direta utilizando dois tipos de sutura da musculatura abdutora. Fizeram parte do estudo 43 pacientes com osteoartrite do quadril unilateral submetidos à ATQ primária pela via de acesso lateral direta. A alocação dos pacientes foi feita de modo quase randomizado, sendo 19 pacientes submetidos à sutura do tipo transóssea e 24 à sutura do tipo transtendínea. Foram avaliados os parâmetros cinemáticos da marcha dos pacientes no período pré-operatório e com seis meses de pós-operatório, e em relação ao tipo de sutura da musculatura abdutora. Não houve diferença estatística nos parâmetros cinemáticos da marcha avaliados em relação ao tipo de sutura da musculatura abdutora na ATQ primária pela via de acesso lateral direta.The evolution of total hip arthroplasty (THA) has been improved by information produced from gait analysis, and it is possible to objectively evaluate hip function after a total joint replacement. The results can be used to study the factors that influence the outcome of the surgery, such as types of access, implants and postoperative rehabilitation. The lateral direct surgical approach described by Hardinge in 1982 provides an excellent exposure to the anterior portion of the hip joint and proximal femur, but with drawbacks that is the necessity to detach the anterior and medial part of the gluteus medius muscle from the greater trochanter to obtain access to the hip joint. Despite its adequate reinsertion, there may be abductor insufficiency after THA, as a consequence of the postoperative avulsion of this suture, resulting in abductor weakness, compromising the gait. The objective of the study was to compare gait parameters after THA via the direct lateral approach using two types of abductor muscle suture. The study included 43 patients with unilateral hip osteoarthritis who have undergone primary THA performed via direct lateral surgical approach. The patients were allocated in a quasi-randomized manner, 19 of whom were submitted to transosseous suture and 24 to transtendineal suture. The kinematic parameters of the gait of patients were analyzed preoperatively and 6 months after surgery, and in relation to the type of the abductor muscle suture. There was no statistically significant difference regarding the kinematic gait parameters between the two types of the abductor muscle suture in the THA via the direct lateral surgical approach.
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Martins, Hugo Filipe Fastio. "Biomechanical investigation of suture patterns to repair the incision of the deep gluteal muscle during total hip replacement in dogs." Master's thesis, Universidade Técnica de Lisboa. Faculdade de Medicina Veterinária, 2013. http://hdl.handle.net/10400.5/5966.
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Dissertação de Mestrado Integrado em Medicina VeterináriaChoice of the best technique to repair surgical transected deep gluteal muscles during total hip replacement in dogs is influenced by multiple factors: properties of the muscle, suture diameter and characteristics, suture pattern biomechanics, amount of foreign material and muscle healing. The best suturing technique has to resist the strength formed during early active exercise protocols while maintaining the margins of the incision in close proximity. In this study was tested the biomechanical properties of interrupted Horizontal Mattress pattern (HM), the best resistant to tension technique advocated to repair transected muscles, and Schiller Suture pattern (SS), a newly developed technique created by Dr. Teresa Schiller used to repair the incision of the deep gluteal muscle during total hip replacement in dogs. The mechanical properties of the patterns were assessed through vertical mechanical traction single pull-to-failure destructive tests on a custom-made tensiometer equipped with a WH-A08 portable scale. Forty 6x10cm unidirectional soft polyethylene foam samples were used as a matrix for implantation of the suture patterns. All samples were preloaded with 9.8 N during one minute and strain was employed through application of force at a rate of 0.415±0.063 N/s. The recorded variables were suture pull-out value (SPOV), Mode of failure (MOF), Total amount of foreign material (TSM), gap at preload (GAP), dynamic displacement at 1, 2, 3 and 4 Kgf, at 80% and 90% the SPOV and at SPOV. Stiffness was calculated at 2 Kgf. Results showed that no significant differences were found between SPOVs of both groups. According to MOF, all SS failed by cut-through, 35% of which failed in both margins. In HM 85% failed by transection and approximately 72% of the stitches failed in the site of knot implantation. Differences in TSM were not considerable in normal sized deep gluteal muscles. Displacement at SPOV was higher in the HM group (32.9 x10-3±2.79 x10-3m) than in SS group (22.6 x10-3±2.2 x10-3m), F (1, 38) = 177.95, p<0.001. GAP and other dynamic displacements were also significantly higher in HM group (U= 0, p<0.001). Stiffness was significantly greater for SS (Mdn= 4903.25 N/m) than for HM group (Mdn= 1634.42 N/m), U= 0, p<0.001, r= 0.87. For these reasons, we concluded that SS represents the best option to repair the incision of the deep gluteal muscles in dogs.
RESUMO - INVESTIGAÇÃO BIOMECÂNICA DE PADRÕES DE SUTURA PARA REPARAR INCISÕES DO GLÚTEO PROFUNDO DURANTE ARTROPLASTIA TOTAL DA ANCA EM CÃES - A escolha da melhor técnica para reparar incisões do glúteo profundo durante artroplastia total da anca em cães é influenciada por múltiplos fatores: propriedades do músculo, diâmetro e características da sutura, biomecânica do padrão de sutura, quantidade de sutura, e reparação celular dos músculos. A técnica de sutura tem que resistir às forças formadas durante os protocolos de atividade precoce enquanto mantém aproximadas as margens da incisão. Neste estudo testaram-se as propriedades biomecânicas do padrão de sutura em “U” horizontal (HM), o mais resistente à tensão utilizado na reparação de incisões de músculos, e do padrão de sutura de Schiller (SS), uma técnica recentemente desenvolvida pela Dra. Teresa Schiller utilizada na reparação do glúteo profundo durante artroplastia total da anca em cães. As propriedades mecânicas dos padrões de sutura foram obtidas através de testes de tração vertical destrutivos num tensiómetro baseado num projeto original equipado com uma balança portátil vertical WH-A08. Quarenta amostras de espuma de polietileno unidirecional com 6x10cm foram usadas como matriz para implantação dos padrões de sutura. Todas as amostras sofreram uma pré-carga de 9.8 N durante 1 minuto e em seguida a força de distensão foi aplicada a um ritmo de 0.415±0.063 N/s. As variáveis registadas foram “valor de arranque de sutura” (SPOV), modo de falha (MOF), material de sutura total (TSM), deslocamento na pré-carga (GAP), deslocamento dinâmico em 1, 2, 3 e 4 Kgf, a 80% e 90% da SPOV, e no SPOV. A rigidez foi calculada aos 2 Kgf. Não foram encontradas diferenças significativas entre os SPOVs de ambos os grupos. De acordo com o MOF, todos os SS falharam através de corte longitudinal, dos quais 35% falharam em ambas as margens. No HM 85% falharam por transecção e 72% dos pontos falharam no local de implantação do nó. As diferenças encontradas no TSM não foram consideráveis para músculos de tamanho normal. O deslocamento no SPOV foi maior no grupo HM (32.9 x10-3±2.79 x10-3m) que no grupo SS (22.6 x10-3±2.2 x10-3m), F (1, 38) = 177.95, p<0.001. O GAP e os restantes deslocamentos dinâmicos foram também superiores no grupo HM (U= 0, p<0.001). A rigidez foi maior no SS (Mdn= 4903.25 N/m) que no HM (Mdn= 1634.42 N/m), U= 0, p<0.001, r= 0.87. Por estas razões concluiu-se que o padrão SS representa a melhor opção para reparar a incisão do glúteo profundo em cães.
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Altieri, Roberta. "Platelet lysate hydrogel-coated suture threads for tendon tissue engineering." Master's thesis, Alma Mater Studiorum - Università di Bologna, 2018.
Find full textAbstract:
Tendon injuries constitute significant clinical problems ascribable both to the limit natural healing capacity of this tissue and to the inefficiency of the current repair treatments. Tendon tissue engineering (TTE) represents an alternative approach that, through highly multidisciplinary strategies and techniques, aims to promote the generation of adequate tissue engineered tendons. Particularly, the development of biomimetic and micro-engineered hydrogels has been broadly investigated as a potential strategy, due to their ability to provide physiological support for cells mimicking the cellular instructive microenvironment. Based on this concept, herein, it is explored the use of platelet lysate (PL) to create a hydrogel layer as a depot of therapeutic factors to induce tenogenic differentiation of encapsulated human adipose-derived stem cells (hASCs). Thus, commercially available silk suture threads were first immersed into a thrombin/calcium chloride (CaCl2) solution and then incubated in PL, containing hASCs, to allow the hydrogel formation. Interestingly, cells were found viable and able to sense the presence of chemotactic factors, being aligned within and at the surface of the thread core. Furthermore, the presence of an ordered newly synthesized extracellular matrix (ECM) together with the expression of tendon-related markers demonstrate the potential use of this method for the generation of a tendon-specific microenvironment. Finally, the impressive silk sutures mechanical properties discovered, suggest the perspective clinical applications of these constructs to bridge injured tendons or as starting blocks in the development of more complex constructs for tendon repair approaches.
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Jonnalagadda, Silpa P. "Standardization of test methodology: a comparison between three suture anchors." Thesis, Texas A&M University, 2005. http://hdl.handle.net/1969.1/2442.
Full textAbstract:
Suture anchors have been used successfully in many applications in orthopedics. They have been in the forefront of research in the recent years. Most of the studies, though, have focused on human suture anchors. This research concentrates on the veterinary aspect of suture anchors. Currently, there is no standardization of testing methods. One of the objectives of this research is to develop a standardized method of testing that is clinically relevant, at least for veterinary use. Another objective of this research is to compare the durability of three commercial suture anchors manufactured by Innovative Animal Products, Securos Veterinary Orthopedic Inc. and IMEXTM by comparing their pullout loads after cyclic loading. This research also aims to determine whether suture anchor failure due to eyelet cut-out or suture wear-out resulting from the sharp edges of the eyelet is the major cause of failure of bone-suture anchor-bone complexes. Cyclic loading of suture anchors during testing for durability has not been used previously even though such loading plays an important role in determining the stability of the bone-suture anchor-bone construct. The response of the construct to this type of testing followed by pullout tests has been explored in this research.
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Samson, Genevieve. "Reinforcing Effect of a Cyanoacrylate Adhesive on Surgical Suture Knots." NCSU, 2009. http://www.lib.ncsu.edu/theses/available/etd-03212009-112007/.
Full textAbstract:
Despite the latest polymer materials and surgical suturing techniques, the knot will always be the weakest point of the tied suture loop. In theory, the knot must be as small as possible to prevent an excessive amount of tissue reaction and a delay in healing. There have been reports suggesting that topical cyanoacrylate adhesives could have a reinforcing effect on a surgeonâs knot. Such an outcome could lead to the elimination of knot slippage and the unsatisfactory performance of some surgical knots. The main purpose of this study was to determine if cyanoacrylate adhesive could have a significant reinforcing effect on typical suture types and sizes when tied as a surgeonâs knot. The second aim was to evaluate if the cyanoacrylate adhesive could replace an additional throw in the surgeonâs knot so as to achieve an equivalent mechanical performance. The topical cyanoacrylate adhesive LiquiBand® was combined with six different suture materials (TicronTM, SurgidacTM, Ethilon*, Nurolon*, BiosynTM and PDS*II) in four different sizes (USP 5-0, USP 3-0, USP 0 and USP 1). The surgeonâs knot (2=1) with and without one (2=1=1) and two additional throws (2=1=1=1) were tied in a reproducible way and mechanically tested. Six dependent variables were used to evaluate the performance of each knot with and without adhesive. The performance criteria were: the force at loop failure, the maximum loop-holding force, the loop holding capacity, the knot efficiency, the knot elongation efficiency and the loop distraction. From the results and from scanning electron microscopic observations of the reinforced knots, the cyanoacrylate adhesive was found to significantly improve the knot performance. The improvement was superior with braided sutures and with absorbable polymer sutures. The reinforcement was more significant with thicker suture sizes and with the plain surgeonâs knot. Finally, it was found that, according to the six performance criteria, the cyanoacrylate adhesive could not replace an additional throw in the surgeonâs knot.
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Holt, Julie Michelle. "On the maxillomalar suture and the assessment of group affiliation." Thesis, Wichita State University, 2008. http://hdl.handle.net/10057/2101.
Full textAbstract:
The following research aims to determine whether or not the maxillomalar suture can determine group affiliation via quantitative assessment. Until now the standard method of determination involved a visual assessment of the shape of the suture, which can be biased. Quantification of this method would allow for more accuracy in the determination and greater repeatability of results. Twenty-three measurements were taken on two hundred and nine Black and White males at the Todd Collection in Cleveland and fifty Native American individuals of unknown age and sex from the Libben Site Collection housed at Kent State University. Three measurements were developed to measure the bimaxillary breaths from different points directly on the maxillomalar suture and three qualitative classifications were used to assess the visual shape. The three bimaxillary suture measurements appear to be the best indicators for group affiliation compared to the other metric measurements. Native Americans had the highest mean for those measurements, indicating the widest facial crania, while Blacks had the lowest means. The bimaxillary breadth measures were all statistically significant at the .05 alpha level. There was slight difference between groups in the maxillomalar suture length noted and this difference was statistically significant on the right side only. The visual qualitative assessment showed recognizable variation in the White and Black samples and very little in the Native American sample.Wichita State University, College of Liberal Arts and Science, Dept. of Anthropology
Includes bibliographic references (leaves 53-57)
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Lin, Erica (Erica S. C. ). "Bio-inspired design of geometrically-structured suture interfaces and composites." Thesis, Massachusetts Institute of Technology, 2015. http://hdl.handle.net/1721.1/98580.
Full textAbstract:
Thesis: Ph. D., Massachusetts Institute of Technology, Department of Materials Science and Engineering, 2015.This electronic version was submitted by the student author. The certified thesis is available in the Institute Archives and Special Collections.
Cataloged from student-submitted PDF version of thesis.
Includes bibliographical references (pages 90-93).
Nature is filled with incredible examples of multi-functional materials that have evolved to possess tailored mechanical behavior. This thesis explores the structure-function-property relationship and design principles of geometrically-structured suture interfaces and composites. Suture interfaces are mechanical structures found in rigid natural materials (e.g. human skulls, turtle shells, seashells) that bear loads and provide flexibility for respiration and growth. The geometry of suture interfaces has been shown to vary within species, across species, through development, and over time as organisms evolve. Using mechanical testing of 3D-printed, bio-inspired prototypes, finite element simulations, and analytical modeling, this thesis offers a systematic, comprehensive understanding of the relationship between suture interface geometry and mechanical behavior and provides insight into the suture interface geometries that exist in nature. Triangular, general trapezoidal, and hierarchical suture interfaces and composites are designed, fabricated, and tested. The stiffness, strength, toughness, and failure mechanisms of suture interfaces are shown to be directly influenced by suture geometry. Therefore, mechanical behavior of suture interfaces can be tailored or amplified through small changes in geometry. In addition, the bending behavior of suture composites can also be tailored through changes in suture interface geometry. With a detailed understanding of the deformation mechanisms of suture composites, optimal, multi-scale, hierarchical geometries can be designed.
by Erica Lin.
Ph. D.
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Bailey, Wayne Richard. "The structural evolution of a microplate suture zone, SW Cyprus." Thesis, Durham University, 1997. http://etheses.dur.ac.uk/1575/.
Full text
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Черкас, Софія Сергіївна. "Suture materials. Requirements for materials. The specifics of the application." Thesis, Київський національний університет технологій та дизайну, 2017. https://er.knutd.edu.ua/handle/123456789/7341.
Full text
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Faustino, Decibel Villarisco. "Late mesozoic magmatism along the Bangong-Nujiang suture zone, Tibet." Thesis, Click to view the E-thesis via HKUTO, 2009. http://sunzi.lib.hku.hk/hkuto/record/B42664615.
Full text
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Holt, Julie Michelle Moore-Jansen Peer H. "On the maxillomalar suture and the assessment of group affiliation." A link to full text of this thesis in SOAR, 2008. http://hdl.handle.net/10057/2101.
Full textAbstract:
Wichita State University, College of Liberal Arts and Science, Dept. of Anthropology.Copyright 2008 by Julie Michelle Holt. All Rights Reserved. Includes bibliographical references (leaves 53-57).
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Coussens, Anna Kathleen. "Molecular regulation of calvarial suture morphogenesis and human craniofacial diversity." Thesis, Queensland University of Technology, 2007. https://eprints.qut.edu.au/16481/1/Anna_Coussens_Thesis.pdf.
Full textAbstract:
This body of work is concerned with the genetics of craniofacial morphology and specifically with that of the cranial sutures which form fibrous articulations between the calvarial bones. The premature fusion of these sutures, known as craniosynostosis, is a common developmental abnormality and has been extensively utilised here as a tool through which to study the genetics of suture morphogenesis and craniofacial diversity.
Investigations began with a search for polymorphisms associated with normal variation in human craniofacial characteristics. Denaturing High-Performance Liquid chromatography was used to identify polymorphisms in two genes causative for
craniosynostosis by analysing DNA from a large cohort of individuals from four
ethnogeographic populations. A single nucleotide polymorphism in fibroblast growth factor receptor 1 was identified as being associated with variation in the cephalic index, a common measure of cranial shape.
To further, and specifically, investigate the molecular processes of suture morphogenesis gene expression was compared between unfused and prematurely fusing/fused suture tissues isolated from patients with craniosynostosis. Two approaches, both utilising Affymetrix gene expression microarrays, were used to identify genes differentially expressed during premature suture fusion. The first was a novel method which utilised the observation that explant cells from both fused and unfused suture tissue, cultured in minimal medium, produce a gene expression profile characteristic of minimally differentiated osteoblastic cells. Consequently, gene expression was compared between prematurely fused suture tissues and their corresponding in vitro de-differentiated cells. In addition to those genes known to be involved in suture morphogenesis, a large number of novel genes were identified which were up-regulated in the differentiated in vivo state and are thus implicated in premature suture fusion and in vivo osteoblast differentiation.
The second microarray study involved an extensive analysis of 16 suture tissues and compared gene expression between unfused (n=9) and fusing/fused sutures (n=7).
Again, both known genes and a substantially large number of novel genes were identified as being differentially expressed. Some of these novel genes included retinol binding protein 4 (RBP4), glypican 3 (GPC3), C1q tumour necrosis factor 3 (C1QTNF3), and WNT inhibitory factor 1 (WIF1). The known functions of these genes are suggestive of potential roles in suture morphogenesis. Realtime quantitative RT PCR (QRT-PCR) was used to verify the differential expression patterns observed for 11 genes and Western blot analysis and confocal microscopy was used to investigate the protein expression for 3 genes of interest. RBP4 was found to be localised on the ectocranial surface of unfused sutures and in cells lining the osteogenic fronts while GPC3 was localised to suture mesenchyme of unfused sutures.
A comparison between each unfused suture (coronal, sagittal, metopic, and lambdoid) demonstrated that gene expression profiles are suture-specific which, based on the identification of differentially expressed genes, suggests possible molecular bases for the differential timing of normal fusion and the response of each suture to different craniosynostosis mutations. One observation of particular interest was the presence of cartilage in unfused lambdoid sutures, suggesting a role for chondrogenesis in posterior skull sutures which have generally been thought to develop by intramembranous ossification without a cartilage precursor.
Finally, the effects of common media supplements used in in vitro experiments to stimulate differentiation of calvarial suture-derived cells were investigated with respect to their ability to induce in vivo-like gene expression. The response to standard differentiation medium (ascorbic acid + β-glycerophosphate) with and without dexamethasone was measured by both mineralisation and matrix formation assays and QRT-PCR of genes identified in the above described microarray studies. Both media induced collagen matrix and bone nodule formation indicative of differentiating osteoblasts. However, the genes expression profiles induced by both media differed and neither recapitulated the levels and profiles of gene expression observed in vivo for cells isolated from both fused and unfused suture tissues. This study has implications for translating results from in vitro work to the in vivo situation. Significantly, the dedifferentiation microarray study identified differentially expressed genes whose products may be considered candidates as more appropriate osteogenic supplements that may be used during in vitro experiments to better induce in vivo-like osteoblast differentiation.
This study has made a substantial contribution to the identification of novel genes and pathways involved in controlling human suture morphogenesis and craniofacial diversity. The results from this research will stimulate new areas of inquiry which will one day aid in the development of better diagnostics and therapeutics for craniosynostosis, and other craniofacial and more general skeletal abnormalities.
41
Coussens, Anna Kathleen. "Molecular regulation of calvarial suture morphogenesis and human craniofacial diversity." Queensland University of Technology, 2007. http://eprints.qut.edu.au/16481/.
Full textAbstract:
This body of work is concerned with the genetics of craniofacial morphology and specifically with that of the cranial sutures which form fibrous articulations between the calvarial bones. The premature fusion of these sutures, known as craniosynostosis, is a common developmental abnormality and has been extensively utilised here as a tool through which to study the genetics of suture morphogenesis and craniofacial diversity. Investigations began with a search for polymorphisms associated with normal variation in human craniofacial characteristics. Denaturing High-Performance Liquid chromatography was used to identify polymorphisms in two genes causative for craniosynostosis by analysing DNA from a large cohort of individuals from four ethnogeographic populations. A single nucleotide polymorphism in fibroblast growth factor receptor 1 was identified as being associated with variation in the cephalic index, a common measure of cranial shape. To further, and specifically, investigate the molecular processes of suture morphogenesis gene expression was compared between unfused and prematurely fusing/fused suture tissues isolated from patients with craniosynostosis. Two approaches, both utilising Affymetrix gene expression microarrays, were used to identify genes differentially expressed during premature suture fusion. The first was a novel method which utilised the observation that explant cells from both fused and unfused suture tissue, cultured in minimal medium, produce a gene expression profile characteristic of minimally differentiated osteoblastic cells. Consequently, gene expression was compared between prematurely fused suture tissues and their corresponding in vitro de-differentiated cells. In addition to those genes known to be involved in suture morphogenesis, a large number of novel genes were identified which were up-regulated in the differentiated in vivo state and are thus implicated in premature suture fusion and in vivo osteoblast differentiation. The second microarray study involved an extensive analysis of 16 suture tissues and compared gene expression between unfused (n=9) and fusing/fused sutures (n=7). Again, both known genes and a substantially large number of novel genes were identified as being differentially expressed. Some of these novel genes included retinol binding protein 4 (RBP4), glypican 3 (GPC3), C1q tumour necrosis factor 3 (C1QTNF3), and WNT inhibitory factor 1 (WIF1). The known functions of these genes are suggestive of potential roles in suture morphogenesis. Realtime quantitative RT PCR (QRT-PCR) was used to verify the differential expression patterns observed for 11 genes and Western blot analysis and confocal microscopy was used to investigate the protein expression for 3 genes of interest. RBP4 was found to be localised on the ectocranial surface of unfused sutures and in cells lining the osteogenic fronts while GPC3 was localised to suture mesenchyme of unfused sutures. A comparison between each unfused suture (coronal, sagittal, metopic, and lambdoid) demonstrated that gene expression profiles are suture-specific which, based on the identification of differentially expressed genes, suggests possible molecular bases for the differential timing of normal fusion and the response of each suture to different craniosynostosis mutations. One observation of particular interest was the presence of cartilage in unfused lambdoid sutures, suggesting a role for chondrogenesis in posterior skull sutures which have generally been thought to develop by intramembranous ossification without a cartilage precursor. Finally, the effects of common media supplements used in in vitro experiments to stimulate differentiation of calvarial suture-derived cells were investigated with respect to their ability to induce in vivo-like gene expression. The response to standard differentiation medium (ascorbic acid + β-glycerophosphate) with and without dexamethasone was measured by both mineralisation and matrix formation assays and QRT-PCR of genes identified in the above described microarray studies. Both media induced collagen matrix and bone nodule formation indicative of differentiating osteoblasts. However, the genes expression profiles induced by both media differed and neither recapitulated the levels and profiles of gene expression observed in vivo for cells isolated from both fused and unfused suture tissues. This study has implications for translating results from in vitro work to the in vivo situation. Significantly, the dedifferentiation microarray study identified differentially expressed genes whose products may be considered candidates as more appropriate osteogenic supplements that may be used during in vitro experiments to better induce in vivo-like osteoblast differentiation. This study has made a substantial contribution to the identification of novel genes and pathways involved in controlling human suture morphogenesis and craniofacial diversity. The results from this research will stimulate new areas of inquiry which will one day aid in the development of better diagnostics and therapeutics for craniosynostosis, and other craniofacial and more general skeletal abnormalities.
42
Velasco, António Tomás Frederico Baptista de Melo d'Orey. "Sutura urbana no vale." Master's thesis, Universidade de Lisboa, Faculdade de Arquitetura, 2017. http://hdl.handle.net/10400.5/13837.
Full text
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Escudero, Tacusi-Oblitas Fresia Narda, and Asto Deybbit Jordy Quiquinlla. "Evaluación de la osificación de la sutura media palatina y la discrepancia transversal maxilar en pacientes de 18 a 40 años de un centro radiológico de Lima - Perú." Bachelor's thesis, Universidad Peruana de Ciencias Aplicadas (UPC), 2019. http://hdl.handle.net/10757/628128.
Full textAbstract:
Objetivo: Evaluación de la osificación de la sutura media palatina y la discrepancia transversal maxilar en pacientes de 18 a 40 años de un centro radiológico de Lima - Perú.
Materiales y métodos: Se realizó un estudio observacional de corte transversal. La muestra estuvo constituída por 234 tomografías computarizadas de haz cónico en pacientes de 18 a 40 años de edad, donde se realizó el análisis de Penn CBCT para la evaluación de la discrepancia transversal maxilar mientras que la clasificación de Angelieri se utilizó para evaluar la osificación de la sutura media palatina. Se utilizaron las pruebas de Chi cuadrado, U Mann Whitney y Correlación de Spearman para evaluar si existe relación entre las variables de estudio.
Resultados: La discrepancia transversal fue de 7.27mm. Por otro lado, se encontró que en el rango de 18 a 28 años de edad prevalece el estado B con 65 pacientes, mientras que en el rango de 29 a 40 años hubieron 50 pacientes del mismo estado. Así mismo, existe asociación entre la discrepancia transversal maxilar con el género, mientras que la osificación de la sutura media palatina no está relacionada al género.
Conclusiones: Se concluye que no se encontró una asociación entre la osificación de la sutura media palatina, la discrepancia transversal y la edad, esto indica que cada variable es independiente. Por otro lado, existe asociación entre la discrepancia transversal maxilar y el género.Objective: Evaluation of the ossification of the mid-palatal suture and the maxillary transverse discrepancy in patients aged 18 to 40 years from a radiological center in Lima-Peru. Materials and methods: An observational cross-sectional study was conducted. The sample consisted of 234 conical beam CT scans in patients aged 18 to 40 years, where the CBCT Penn analysis was performed for the evaluation of the maxillary transverse discrepancy, while the Angelieri classification was used to evaluate the ossification of the mid palatal suture. Chi Square, Mann–Whitney U, and Spearman Correlation tests were used to assess whether there was a relationship between the study variables. Results: The transverse discrepancy was 7.27 mm. On the other hand, it was found that in the range of 18 to 28 years of age, state B prevails with 65 patients, while in the range of 29 to 40 years there were 50 patients of the same state. Likewise, there was an association between the maxillary transverse discrepancy with the gender, while the ossification of the mid-palatal suture was not related with the gender. Conclusions: It was concluded that no association was found between the ossification of the mid-palatal suture, the transverse discrepancy, and age; this indicates that each variable is independent. On the other hand, there was an association between maxillary transversal discrepancy and gender.
Tesis
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Connerney, Jeannette J. "Balance between Formation of Twist1 Homodimer and Heterodimer Regulate Suture Fusion." Fogler Library, University of Maine, 2007. http://www.library.umaine.edu/theses/pdf/ConnerneyJJ2007.pdf.
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Monte, Fernando Ferreira Del. "Desenvolvimento de elementos de fixação (âncoras de suturas) em materiais biocompatíveis através de processo de Manufatura Aditiva." Universidade de São Paulo, 2016. http://www.teses.usp.br/teses/disponiveis/18/18146/tde-04052017-103304/.
Full textAbstract:
Atualmente a área de saúde vem buscando auxílio na engenharia para a contribuição no estudo e confecção de próteses para casos específicos de fraturas ou doenças ósseas. Com o avanço da tecnologia surgiram processos de manufatura que tornam possível a fabricação de próteses personalizadas. Uma dessas tecnologias é a manufatura aditiva. O grande desafio no momento está na fabricação de próteses por manufatura aditiva que combinem desempenho biomecânico e resistência estrutural. Nesse contexto, o objetivo deste trabalho é desenvolver elementos de fixação, especificamente âncoras de sutura de polímeros PEEK e PEKK, considerando seus requisitos estruturais através de simulações pelo método dos elementos finitos, e considerando que sejam fabricadas através de processos de manufatura aditiva. Este desenvolvimento permitirá a substituição de âncoras de sutura de liga de titânio, hoje largamente empregadas pelos cirurgiões, por âncoras de sutura de polímeros biocompatíveis, o que possibilitará que estes polímeros sejam absorvidos pelo corpo humano em curto e médio prazo, permitindo a completa restituição do osso afetado, melhorando a qualidade de vida do paciente pós-cirurgia. Os resultados obtidos neste trabalho indicam que a técnica poderá resultar em próteses com a biocompatibilidade desejada e resistência mecânica adequada. Próteses permanentes (articulações) ou provisórias (âncoras de sutura) seriam um dos critérios para a escolha do material a ser utilizado, absorvível ou não pelo corpo humano.Nowadays medicine is searching assistance from engineering that may contribute in studies and confection of prothesis to specific cases of fractures and bone diseases. With the advance of technology new processes of manufacture were risen, making possible the confection of personalized prothesis. The biggest challenge of the moment is in the manufacture of additive prothesis that can combine biomechanics performance and structural resistance. In this context, the objective of this dissertation is to develop PEEK and PEKK polymer suture anchors, considering its structural requirements, taking into account their mechanical strength, through simulation by the finite element method, and considering additive manufacturing processes. This development will allow the replacement of titanium alloy suture anchors, now widely used by surgeons by suture anchors of biocompatible polymers, which enable these polymers to be absorbed by the human body in the short and medium term, allowing full regeneration of affected bone, improving the quality of life of the patient. The results of this study indicate that the technique could result in prosthesis with the desired biocompatibility and adequate mechanical strength. Permanent prosthesis (joints) or temporary (suture anchors) would be one of the criteria for the choice of material to be used, absorbable or non absorbable by the human body.
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Rocha, Artur Gouveia [UNESP]. "Âncora de titânio na sutura iliofemoral para tratamento de luxação coxofemoral traumática em cães: descrição da técnica e estudo de 12 casos." Universidade Estadual Paulista (UNESP), 2017. http://hdl.handle.net/11449/151284.
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As técnicas cirúrgicas extra-articulares para estabilização do qua-dril luxado têm sido mais estudadas, tendo em vista a manutenção da integridade da cartilagem articular e a redução da progressão da doença articular degenerativa. Den-tre estas técnicas, a sutura de fixação iliofemoral, tem se mostrado efetiva, com boa recuperação dos pacientes. O propósito deste trabalho foi avaliar a âncora de titânio como método de fixação do fio se sutura ao ílio, substituindo, assim, na técnica de fixação iliofemoral, a trabalhosa manobra de passagem do material de sutura através de um túnel no corpo ilíaco. Esta técnica foi realizada em 12 cães, de raças variadas, atendidos no Hospital Veterinário da UNESP – Jaboticabal. Os pacientes, em sua to-talidade, vítimas de atropelamento, se apresentaram com diferentes graus de claudi-cação e dor no quadril. Em alguns casos, ocorreram reluxações após tentativas de redução fechada e esses pacientes foram submetidos redução e fixação cirúrgica da luxação por meio da sutura iliofemoral modificada. Os pacientes foram acompanhados clínica e radiograficamente por períodos variados entre 30 a 90 dias de pós-operatório. Observou-se apoio com carga no membro em média de três dias após os procedi-mentos e aos 10 dias a maioria dos pacientes não claudicava. Não foram visibilizadas, no exame radiográfico osteólise perimplante. A sutura ílio femoral, modificada pela utilização de uma âncora fixada ao ílio, mostrou-se eficiente no tratamento da luxação coxofemoral, não sendo observada recidiva da luxação. Adicionalmente, a utilização da âncora de titânio facilitou sobremaneira a fixação do fio ao ílio, reduzindo significa-tivamente o tempo cirúrgico.
Extra-articular surgical techniques for stabilization of dislocated hip have been most studied, with a view to maintaining the integrity of articular cartilage and reducing the progression of degenerative joint disease. Among these techniques, the suture fixation iliofemoral, has proven effective, with good recovery of patients. The purpose of this study was to evaluate the anchor titanium as the wire clamping method suture the ileum, thus replacing, in the iliofemoral fixation technique, the laborious ma-neuvering passage of suture material through a tunnel in iliac body. This technique was performed in 10 dogs of various races attended at UNESP Veterinary Hospital – Jaboticabal. The patients, in its entirety, victims of trampling presented with varying degrees of lameness and pain in the hip. In some cases, attempts occurred after reluxações closed reduction and forami these patients undergoing surgical fixation and reduction of the dislocation by modified iliofemoral suture. The patients were followed clinically and radiographically for varying periods between 30 to 90 days postopera-tively. He observed the load support member on average 3 days after the procedure and 10 days most patients do not limping. There were visualized on radiographic ex-amination, perimplante osteolysis, or the appearance of osteophytes or joint sclerosis. The ilium femoral suture, modified by the use of an anchor attached to the ilium, was efficient in the treatment of hip dislocation, not being observed dislocation recurrence. Additionally, the use of titanium anchor greatly facilitating the fixing of the wire ilium, significantly reducing surgical time.
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Safaya, Smriti. "Neotectonic faulting along the central Bangong-Jiang suture zone, central Tibet." Thesis, Click to view the E-thesis via HKUTO, 2006. http://sunzi.lib.hku.hk/hkuto/record/B37105309.
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Connor, Elaine Catharine. "The role of hedgehog signalling in calvarial bone and suture development." Thesis, King's College London (University of London), 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.424472.
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Nageotte, Florent. "Contributions à la suture assistée par ordinateur en chirurgie mini-invasive." Université Louis Pasteur (Strasbourg) (1971-2008), 2005. https://publication-theses.unistra.fr/public/theses_doctorat/2005/NAGEOTTE_Florent_2005.pdf.
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La suture est un geste courant mais difficile en chirurgie coelioscopique. Les mouvements possibles des instruments sont limités en raison du passage des instruments par un point fixe et le retour visuel fourni est indirect et bidimensionnel. Il est donc très difficile pour les chirurgiens de planifier les mouvements de l'aiguille de suture. En pratique, le passage de l'aiguille dans les tissus fait intervenir des déformations indésirables des tissus. Afin d'aider les chirurgiens à planifier le passage d'une aiguille circulaire dans des tissus fins, nous proposons d'étudier la cinématique des mouvements possibles. Nous recherchons tout d'abord dans quels cas il est possible de trouver des chemins sans déformation entre deux points à la surface des tissus. Nous montrons qu'il existe des conditions simples sur la prise d'aiguille et sur le placement du trocart permettant de garantir l'existence de tels chemins. Nous proposons ensuite une méthode pratique de planification permettant de générer des chemins dits à déformation minimale. La planification de chemin nécessite la connaissance de données spatiales comme la position de l'aiguille dans le porte-aiguille. Nous proposons d'obtenir ces informations en utilisant une caméra endoscopique couleur. Nous utilisons des méthodes de traitement d'images simples permettant d'obtenir l'extraction des informations image en temps réel. La reconstruction des données spatiales est basée sur une optimisation itérative des erreurs de reprojection par asservissement visuel virtuel. Enfin, nous avons proposé des outils de réalité augmentée permettant d'assister le chirurgien durant une suture. Nous montrons également la faisabilité d'une aide robotisée à la suture en réalisant un passage d'aiguille semi-autonome dans des conditions de laboratoire. Ce travail exploratoire ouvre de nombreuses possibilités d'applications pour la mise en place d'une véritable aide à la suture par ordinateurSuturing is a common but difficult task in laparoscopic surgery. The motions of the surgical instruments are limited because of the trocart constraint and the vision of the scene obtained through an endoscopic camera is reduced to 2D images. Consequently, it is difficult for the surgeons to plan the movements of the suturing needle. Usually, the stitching task is realized by multiple trials and undesirable deformations of the tissues are involved. In order to help the surgeons to plan the motions of a circular needle through thin tissues, we propose to study the kinematics of the needle and the needle-holder in laparoscopic surgery. Firstly, we have been interested in finding pathes between two points on the surface of the tissu which do not involve deformations. We show that there are simple conditions on the trocart position and the needle handling parameters which guarantee the existence of ideal paths. Then, we explain a method to practically plan special paths for which the deformation of the tissue is minimal. Planning paths requires the knowledge of some 3D information such as the position of the needle in the needle-holder and the position of the trocart with respect to the tissues. We propose to use the color endoscopic camera to get this information. We use fast and simple image processing techniques to extract visual cues from the images in real-time. Then the 3D positions are obtained using a virtual visual servoing scheme which iteratively minimizes the forward projection error in the images. Finally, we propose augmented-reality tools to assist the surgeon during stitching. We also show by controlling a medical robot using a 2D visual servoing scheme, that semi-autonomous suturing is possible in laboratory conditions. This exploratory research work opens the path for a complete computer-aided suturing system
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Abrajevitch, Alexandra. "Paleomagnetism of the Dazhuqu terrane, Yarlung Zangbo suture zone, Southern Tibet." Thesis, Click to view the E-thesis via HKUTO, 2002. http://sunzi.lib.hku.hk/hkuto/record/B42577020.
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