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Dissertations / Theses on the topic 'Synthesis of xanthone'

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Published: 5 June 2025

Last updated: 15 July 2025

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1

Cho, Woo Cheal. "Synthesis of caged Garcinia xanthone analogues." Diss., [La Jolla] : University of California, San Diego, 2009. http://wwwlib.umi.com/cr/ucsd/fullcit?p1469234.

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Thesis (M.S.)--University of California, San Diego, 2009.<br>Title from first page of PDF file (viewed October 13, 2009). Available via ProQuest Digital Dissertations. Vita. Includes bibliographical references.

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2

Mancini, Michael. "Approaches to the synthesis of xanthone analogs of the anthracycline class of anticancer agents." Thesis, McGill University, 1985. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=72059.

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Several strategies outlining approaches to the synthesis of the heteroanthracyclinones 4-demethoxyxanthodaunomycinone and 4-demethoxyisoxanthodaunomycinone (7,8,9,10-tetrahydrobenzo(b)-6,7,9,11-tetrahydroxy-9-acetylxanthen-12 and 5-one) are described.<br>The condensation of tetralin 2-acetyl-5,8-dimethoxy-1,2,3,4-tetrahydro-2-naphthol with o-methoxybenzoic acid was investigated and useful large-scale syntheses of important 1,4-dimethoxy-substituted xanthone intermediates were developed.<br>Diels-Alder cycloaddition reaction between a xanthone-derived o-quinodimethane intermediate and an olefin

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3

Palmeira, Andreia Filipa dos Santos. "Design Synthesis and Evaluation of Xanthone Derivatives for Dual Activity: Antitumor and P-Glycoprotein Inhibition." Doctoral thesis, Faculdade de Farmácia da Universidade do Porto, 2010. http://hdl.handle.net/10216/63796.

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4

Palmeira, Andreia Filipa dos Santos. "Design Synthesis and Evaluation of Xanthone Derivatives for Dual Activity: Antitumor and P-Glycoprotein Inhibition." Tese, Faculdade de Farmácia da Universidade do Porto, 2010. http://hdl.handle.net/10216/63796.

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5

Johann, Laure. "Synthesis and mechanism of 1,4-naphthoquinones as turncoast inhibitors of disulfide reductases affecting the redox equilibrium of schistosomes and malaria parasites." Strasbourg, 2011. https://publication-theses.unistra.fr/restreint/theses_doctorat/2011/JOHANN_Laure_2011_ED222.pdf.

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Cette thèse décrit la synthèse et le mécanisme d'action de nouveaux agents antiparasitaires contre le paludisme et la schistosomiase, deux maladies infectieuses majeures causées respectivement par le protozoaire Plasmodium et l'helminthe Schistosoma mansoni. Chez ces parasites, l’équilibre rédox est maintenu par deux enzymes essentielles et identifiées comme cibles thérapeutiques, la glutathion réductase (GRs : humaine et parasitaire), et la thiorédoxine-glutathion réductase chez le ver (TGR). Des travaux précédents avaient permis l'identification de 3-benzyl-ménadiones antipaludiques, et de l

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6

Kelkar, Avijit S. "Novel syntheses of substituted xanthones." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1999. http://hub.hku.hk/bib/B31238671.

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7

招桂鳳 and Kwei-fung Chiu. "Syntheses and chemistry of some xanthone derivatives." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1995. http://hub.hku.hk/bib/B31234768.

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8

Chiu, Kwei-fung. "Syntheses and chemistry of some xanthone derivatives /." Hong Kong : University of Hong Kong, 1995. http://sunzi.lib.hku.hk/hkuto/record.jsp?B17506633.

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9

Lam, Thanh T. "Synthesis and synthetic studies towards diterpenes, sesquiterpenoids, and the caged Garcinia xanthones." Connect to a 24 p. preview or request complete full text in PDF format. Access restricted to UC campuses, 2007. http://wwwlib.umi.com/cr/ucsd/fullcit?p3274525.

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Thesis (Ph. D.)--University of California, San Diego, 2007.<br>Title from first page of PDF file (viewed October 3, 2007). Available via ProQuest Digital Dissertations. Vita. Includes bibliographical references.

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10

Kotásková, Michaela [Verfasser]. "Synthesis of new xanthene derivatives / Michaela Kotásková." Mainz : Universitätsbibliothek Mainz, 2013. http://d-nb.info/1029903409/34.

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11

Perticarari, Sofia. "Atropisomeric xanthines: Synthesis, stereodynamics and absolute configuration." Master's thesis, Alma Mater Studiorum - Università di Bologna, 2015. http://amslaurea.unibo.it/9025/.

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During the thesis period a new class of atropisomeric xanthine derivatives has been studied. We decided to focus our attention on these purine bases because of their various biological activities, that could play an important role in the discovery of new bioactive atropisomers. The synthesized compounds bear an Aryl-N chiral axis in position 1 of the xanthine scaffold, around which the rotation is prevented by the presence of bulky ortho substituents. Through a retro synthetic analysis we synthesized three atropisomeric structures bearing in position 1 of the purine scaffold respectively an o-

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12

Tsuji, Yuichi. "Synthesis of π-System-Layered Structures Based on Rigid Scaffolds". 京都大学 (Kyoto University), 2014. http://hdl.handle.net/2433/188608.

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13

Tallon, Valérie. "Fonctionnalisation des quinoxalines et des cinnolines par réaction d'ortho-métallation." Rouen, 1996. http://www.theses.fr/1996ROUES041.

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La préparation de plusieurs quinoxalines et cinnolines, et en particulier une nouvelle synthèse de la 4-hydroxycinnoline ont été réalisées. Ce travail décrit la fonctionnalisation de la partie hétérocyclique de diverses quinoxalines et cinnolines par la réaction de métallation. La possibilité de métallation sur le cycle benzénique, en péri de l'azote, a aussi été montrée sur les cinnolines, avec l'iode et le chlorure de triméthylsilyle comme électrophiles. Enfin l'interêt de cette réaction de métallation est illustré par la préparation de xanthones et de diazépines.

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14

Kierat, Radosław Marian. "Synthese, Modifikation und biologische Anwendung fluoreszierender Xanthenfarbstoffe." [S.l. : s.n.], 2008. http://nbn-resolving.de/urn:nbn:de:bsz:16-opus-83019.

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15

Tatsuya, Nakano. "Synthesis and Functionalization of Fused Aromatic Ring-layered Compounds." 京都大学 (Kyoto University), 2015. http://hdl.handle.net/2433/199330.

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16

Dejouy, Garance. "Synthèse de nouveaux fluorophores organiques – Application à la conception de substrats fluorogéniques d'enzymes fondés sur le principe de la synthèse in situ." Thesis, Bourgogne Franche-Comté, 2020. http://www.theses.fr/2020UBFCK027.

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La détection et l'imagerie par fluorescence de systèmes biologiques nécessite la mise en place d'outils efficaces, robustes et simples d'utilisation. Les sondes fluorogéniques conventionnelles, actuellement utilisées en microbiologie manquent de précision puisqu'elles résultent de la simple modification chimique de la structure d'un fluorophore déjà formé, conduisant souvent à une extinction incomplète de sa fluorescence intrinsèque. Mes travaux de thèse ont pour but de développer de nouveaux substrats fluorogéniques d'enzymes basés sur le principe du "covalent assembly". Cette approche de syn

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17

Gillespie, Jason A. "Design and synthesis of wide bite angle phosphacyclic ligands." Thesis, University of St Andrews, 2012. http://hdl.handle.net/10023/3100.

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By examining structure activity relationships for a given catalytic reaction it is possible to discover what ligand features and parameters lead to stable and highly active/selective catalyst systems. With this knowledge in hand it may be possible to rationally design next generation ligands and catalysts to affect improved substrate transformations, with higher selectivities and faster reaction times. The success of Burk's DuPhos ligands in asymmetric hydrogenation demonstrated that chiral phosphacycles can be a potent source of chiral induction, whilst in a similar vein the work of van Leeuw

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18

Keddie, Daniel Joseph. "The synthesis of novel profluorescent nitroxide probes." Thesis, Queensland University of Technology, 2008. https://eprints.qut.edu.au/16702/1/Daniel_Keddie_Thesis.pdf.

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A number of novel isoindoline nitroxides have been synthesised using a variety of synthetic techniques. Several carbon-carbon bond forming methodologies, including the first examples of Heck and Sonogashira coupling applied to the isoindoline nitroxide class, were utilised to give novel robust aromatic frameworks. Palladium-catalysed Heck coupling of brominated nitroxides and ester-substituted olefins generates novel nitroxides possessing extended conjugation. Hydrolysis of the nitroxide esters gave the corresponding carboxylic acids, which showed enhanced water solubility. Sonogashira couplin

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19

Keddie, Daniel Joseph. "The synthesis of novel profluorescent nitroxide probes." Queensland University of Technology, 2008. http://eprints.qut.edu.au/16702/.

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A number of novel isoindoline nitroxides have been synthesised using a variety of synthetic techniques. Several carbon-carbon bond forming methodologies, including the first examples of Heck and Sonogashira coupling applied to the isoindoline nitroxide class, were utilised to give novel robust aromatic frameworks. Palladium-catalysed Heck coupling of brominated nitroxides and ester-substituted olefins generates novel nitroxides possessing extended conjugation. Hydrolysis of the nitroxide esters gave the corresponding carboxylic acids, which showed enhanced water solubility. Sonogashira couplin

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20

Van, der Walt Mietha Magdalena. "Syntheses of sulfanylphthalimide and xanthine analogues and their evaluation as inhibitors of monoamine oxidase and as antagonists of adenosine receptors / Mietha Magdalena van der Walt." Thesis, North-West University, 2013. http://hdl.handle.net/10394/9537.

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Currently L-DOPA is the drug most commonly used for the treatment of Parkinson’s disease (PD). However, the long-term use of L-DOPA is associated with the development of motor fluctuations and dyskinesias. Treatment mainly addresses the dopaminergic features of the disease and leaves its progressive course unaffected. An optimal treatment would be a combination of both motor and non-motor symptom relief with neuroprotective properties. Two drug targets have attracted the attention for PD treatment, namely monoamine oxidase B (MAOB) and adenosine A2A receptors. MAO-B inhibitors enhance the elev

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21

Anthore-Dalion, Lucile. "Une Approche Radicalaire à l'Alkylation des Cétones." Thesis, Université Paris-Saclay (ComUE), 2016. http://www.theses.fr/2016SACLX084/document.

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Cette thèse décrit le développement de nouvelles réactions dans le cadre de la chimie radicalaire par transfert de xanthate développée au laboratoire. Nous nous sommes tout particulièrement intéressés à apporter des solutions à l’alkylation formelle de cétones par voie radicalaire. Dans ce cadre, une alkylation bidirectionnelle de cétones non symétriques a été développée à partir de dixanthates. Reposant sur les différences de stabilité des radicaux présents dans le milieu, cette réaction a permis la synthèse de nombreuses cétones formellement dialkylées à partir d’oléfines non activées. La pu

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22

Fromentin, Yann. "Extraction et hémisynthèse d'analogues de la guttiférone A." Thesis, Paris 5, 2013. http://www.theses.fr/2013PA05P633.

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La guttiférone A , appartenant à la famille des PPAPs ou Acyle Phloroglucinol Polycycliques Polyprénylées, est une molécule extraite à partir d’un arbre tropicale, le Symphonia globulifera. Cette matière première est abondante et peut être facilement obtenue. De plus, elle présente de nombreuses activités biologiques, lui conférant un potentiel pharmacologique très intéressant. Trois approches ont été effectuées durant ces travaux. La première fût l’utilisation de microorganismes pour effectuer des biotransformations. L’utilisation de levures a permis de synthétiser la 3,16-oxy-guttiférone A,

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23

Grahner, Bettina. "Synthese und Struktur-Wirkungs-Beziehungen von 9-Desaza-Xanthinen (Pyrrolo[3,2-3]pyrimidin-2,4-dionen) mit hoher Affinität zu Adenosinrezeptoren /." [S.l. : s.n.], 1993. http://www.gbv.de/dms/bs/toc/147932564.pdf.

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24

Klippel, Nadja [Verfasser]. "Synthese und Charakterisierung von Perylendiimid- und Xanthen-funktionalisierten Silica-Nanopartikeln sowie Untersuchungen zu der Farbstoff-Partikel-Wechselwirkung / Nadja Klippel." Saarbrücken : Saarländische Universitäts- und Landesbibliothek, 2021. http://d-nb.info/1238595502/34.

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25

Andrade, Kleber Tellini de. "Síntese, caracterização e aplicação de derivados xantenos em terapia e inativação fotodinâmica." reponame:Repositório Institucional da UFABC, 2017.

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Orientador: Prof. Dr. Anderson Orzari Ribeiro<br>Tese (doutorado) - Universidade Federal do ABC, Programa de Pós-Graduação em Ciência e Tecnologia/Química, Santo André, 2017.<br>Neste trabalho apresentamos a sintese e caracterizacao de derivados de xantenos para emprego como fotossensibilizadores em Terapia Fotodinamica. A sintese de 08 diferentes compostos foi realizada utilizando-se o alcool resorcinol e derivados do anidrido ftalico, na presenca de ZnCl2. Foram utilizadas tecnicas como RMN de 1H, FTIR, espectrometria de massas para comprovar as estruturas e a pureza dos compostos sintetizad

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26

Morrow, Benjamin Joseph. "The synthesis of novel nitroxides and their application as small-molecule antioxidants and profluorescent probes for oxidative stress." Thesis, Queensland University of Technology, 2010. https://eprints.qut.edu.au/39445/1/Benjamin_Morrow_Thesis.pdf.

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The detection and potential treatment of oxidative stress in biological systems has been explored using isoindoline-based nitroxide radicals. A novel tetraethyl-fluorescein nitroxide was synthesised for its use as a profluorescent probe for redox processes in biological systems. This tetraethyl system, as well as a tetramethyl-fluorescein nitroxide, were shown to be sensitive and selective probes for superoxide in vitro. The redox environment of cellular systems was also explored using the tetramethylfluorescein species based on its reduction to the hydroxylamine. Flow cytometry was employed t

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27

Liou, Shiou-Jyh, and 劉修志. "Synthesis and Biological Activities of Xanthone Derivatives." Thesis, 1994. http://ndltd.ncl.edu.tw/handle/83924530575388577198.

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碩士<br>高雄醫學大學<br>藥學研究所<br>82<br>Based on the pharmacological experiments, the xanthonoids related to the constitutents of Gentianaceous plants , such as tripteroside peracetate and northyriol peracetate exhibited potent effect on platelet aggregation. In our laboratory, we synthesized a series of xanthone analogues for study the pharmacological tests and found that 3-hydroxyxanthone, 2,3-dihydroxyxanthone diacetate, 3,4-dihydroxyxanthone and 3,4-dihydroxyxanthone diacetate showed potent inhibition of platelet aggregation induced by arachidonic acid and collagen, respectively. Recently we synt

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28

Hui, Jiang. "Structure and synthesis of lichen xanthones." Phd thesis, 1991. http://hdl.handle.net/1885/138806.

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29

Little, Andrew John. "Studies toward the synthesis of anthraquinone-xanthone heterodimeric natural products." Thesis, 2013. https://hdl.handle.net/2144/14140.

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Anthraquinone-xanthone heterodimeric natural products are a diverse family of polyketides highlighted by a unique bicyclo [3.2.2] ring system which links both anthraquinone and xanthone moieties. Both the connectivity of the unique bicyclic ring system and the oxidation state of the two heterocycles vary among the members of this family of natural products. These molecules have been generally isolated as fungal metabolites but also have shown anticoccidial (xanthoquinodin A:0.02 μg/mL), antibiotic (acremonidins A and C; 32 μM and acremoxanthone, MIC; 12.5 μg/mL), and cytotoxicity against vario

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30

Chai, Chin-Te, and 翟晉德. "Synthesis and Antiproliferative Evaluation of Amide-Containing Anthraquinone, Xanthone, and Carbazole." Thesis, 2014. http://ndltd.ncl.edu.tw/handle/62160015849872604883.

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碩士<br>大仁科技大學<br>製藥科技研究所<br>102<br>Certain amide-containing anthraquinone, xanthone, and carbazole derivatives have been synthesized and evaluated in vitro for their antiproliferative activities against a panel of human cancer cell lines including nasopharyngeal carcinoma (NPC-TW01), lung carcinoma (NCI-H661) and leukemia (Jurkat). Among them, 2-(9,10-dioxo-9,10-dihydroanthracen-2-yloxy)-N-(naphthalen-2-yl)acetamide (13) was the most active against NPC-TW01 with an GI50 value of 2.62 μM while its xanthone and carbazole counterparts, N-(Naphthalen-2-yl)-2-(9-oxo-9H-xanthen-3-yloxy)acetamide (14)

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31

Cheng, Jen-Hao, and 鄭人豪. "Designs, Synthesis, and Biological Evaluation of Chalcone and Xanthone Derivatives as Anticancer Agents." Thesis, 2011. http://ndltd.ncl.edu.tw/handle/71150886895533162608.

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博士<br>高雄醫學大學<br>藥學研究所<br>99<br>Chalcone derivatives (1-14) were synthesized and evaluated for their biological effects in this study. As the results, all synthetic chalcones exhibited cytotoxicities against selected cancer cell lines, especially for compounds 3 and 10 with ethoxyl moiety, showed potent cytotoxicities. In addition, both compounds 3 and 10 possessed anti-inflammatory and antioxidant activities. Compounds 3 and 10 were potential to be served as cancer chemopreventive agents. Xanthone derivatives (16-20 and 22-28) were also synthesized in this study. As the results of biological a

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32

Gengan, Robert Moonsamy. "The synthesis of xanthone derivatives and their enzymatic conversion and inhibition of aflatoxin biosynthesis." Thesis, 1996. http://hdl.handle.net/10413/6391.

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The biosynthesis of Aflatoxin B1 (AFB1) has been the subject of conflicting speculation and numerous reviews. The currently accepted scheme for the aflatoxin pathway is based on data obtained from feeding studies using isotopically labelled precursors. In these studies the conversion of possible intermediate metabolites to AFBl by mutants of Aspergillus parasiticus illustrated their role as biogenetic precursors. Currently there is now agreement on the identity of most of the intermediate Illetabolites involved in the biosynthesis of AFB1. However, there is a lack of clarity on the details of

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33

Oliveira, Filipa Sameiro de. "Prenylated xanthone derivatives : synthesis of structural analogues of α-mangostin and antitumor activity evaluation". Master's thesis, 2012. http://hdl.handle.net/10316/22057.

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Dissertação de mestrado em Química Farmacêutica Industrial, apresentada à Faculdade de Farmácia da Universidade de Coimbra<br>Xanthones or xanthen-9-ones (dibenzo-g-pirone) comprise an important class of oxygenated heterocycles whose role is well-known in Medicinal Chemistry. The biological activities of this class of compounds are associated with their tricyclic scaffold but vary depending on the nature and/or position of the different substituents. To obtain more structural diversity and quantities for biological assays, suitable and efficient synthetic processes are necessary. Different s

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34

Axelrod, Abram Joseph. "Total syntheses of the neuroregenerative natural products vinaxanthone and xanthofulvin and biosynthetic studies." Thesis, 2012. http://hdl.handle.net/2152/30392.

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Total syntheses of the neuroregenerative natural products vinaxanthone and xanthofulvin have been accomplished. The synthetic routes to both molecules utilize a highly regioselective furan Diels-Alder cycloaddition - aromatization sequence to furnish the catechol fragment present in both natural products. The pentasubstituted catechol was elaborated to a vinylogous amide which was used twice in both syntheses, exploiting the pseudosymmetry found in vinaxanthone and xanthofulvin. This approach enabled the dimerization of 5,6-dehydropolivione forming vinaxanthone, lending significant evidence to

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35

Nichols, Alexander Lindsey. "Application of the Moore rearrangement to the synthesis of 1,4-dioxygenated xanthones and efforts toward the total synthesis of lundurine B." Thesis, 2012. http://hdl.handle.net/2152/ETD-UT-2012-12-6750.

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A novel application of the Moore rearrangement was successfully developed and applied to the synthesis of 1,4-dioxygenated xanthones that would have been difficult to obtain otherwise. The 1,4-dioxygenated xanthone moiety is found in several naturally occurring, biologically active compounds. Several methods by which to obtain the 1,4-dioxygenated xanthone core have been reported; however, high step counts, low yields, and harsh reaction conditions preclude the use of these methods to complex xanthone natural products. Using the Moore rearrangement as a key step in the synthetic sequence has

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36

Palmeira, Andreia Filipa dos Santos. "Design Synthesis and Evaluation of Xanthone Derivatives for Dual Activity: Antitumor and P-Glycoprotein Inhibition." Doctoral thesis, 2011. https://repositorio-aberto.up.pt/handle/10216/72451.

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Palmeira, Andreia Filipa dos Santos. "Design Synthesis and Evaluation of Xanthone Derivatives for Dual Activity: Antitumor and P-Glycoprotein Inhibition." Tese, 2011. https://repositorio-aberto.up.pt/handle/10216/72451.

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38

Oliveira, Helder João Ribeiro de. "Synthesis of new carboxylic chiral derivatives of xanthones inspired on marine xanthones." Master's thesis, 2017. https://hdl.handle.net/10216/108584.

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39

Oliveira, Helder João Ribeiro de. "Synthesis of new carboxylic chiral derivatives of xanthones inspired on marine xanthones." Dissertação, 2017. https://hdl.handle.net/10216/108584.

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40

Naidoo, Jeremy Morgan. "Novel methodology for the synthesis of xanthones." Thesis, 2009. http://hdl.handle.net/10539/7360.

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In this MSc, novel methodology for the synthesis of xanthones and related compounds was discovered. It was found that treatment of (1,4-dimethoxynaphthalen-2-yl)(2- hydroxyphenyl)methanone with ceric ammonium nitrate (CAN) resulted in the formation of 12a-methoxy-5H-benzo[c]xanthene-5,7(12aH)-dione as the product. The structure was confirmed by X-ray crystallography. Exposure of a related compound (2,5-dimethoxyphenyl)(2-hydroxyphenyl)methanone to CAN afforded 2-methoxy-9H-xanthen-9-one as the major product with 4amethoxy- 2H-xanthene-2,9(4aH)-dione formed as the minor product. This re

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41

Azevedo, Carlos Miguel Brochado Pinto Gonçalves de. "Synthesis and multidimensional optimization of antitumor xanthones." Doctoral thesis, 2012. https://repositorio-aberto.up.pt/handle/10216/73974.

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42

Azevedo, Carlos Miguel Brochado Pinto Gonçalves de. "Synthesis and multidimensional optimization of antitumor xanthones." Tese, 2012. https://repositorio-aberto.up.pt/handle/10216/73974.

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43

Loureiro, Daniela Raquel Pontes. "Synthesis of marine xanthones : tracking yicathins B and C." Master's thesis, 2016. http://hdl.handle.net/10316/36302.

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44

LIN, ZHENG-SHENG, and 林正生. "Xanthan polysaccharide synthesis in xanthomonas campesstrie." Thesis, 1992. http://ndltd.ncl.edu.tw/handle/66735526338958100072.

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45

Dam, Jean. "Synthetic, mechanistic and biological studies of novel metal-imidazo[1,2-a]pyridines and xanthones." Thesis, 2016. http://hdl.handle.net/10539/21659.

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A thesis submitted to the Faculty of Science, University of the Witwatersrand, Johannesburg, in fulfilment of the requirements for the Degree of Doctor of Philosophy Submitted June 2016.<br>The work detailed in this PhD involves two distinct, separate areas of research. The first project involved an investigation into the synthesis, characterisation and metal-chelation of pyrido-imidazo[1,2-a]pyridines in the search for new compounds for the treatment of cancer. Previously in our laboratories at the University of the Witwatersrand a small library of imidazo[1,2-a]pyridines were synthesized

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46

Araújo, Joana Margarida Soares. "Synthesis of chiral derivatives of xanthones with potential biological activity." Master's thesis, 2019. https://hdl.handle.net/10216/124059.

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47

LIU, CONG-XI, and 劉崇喜. "Synthesis and structure-activity relationship of xanthones, novel antiplatelet agent." Thesis, 1990. http://ndltd.ncl.edu.tw/handle/33249216244817339469.

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48

Araújo, Joana Margarida Soares. "Synthesis of chiral derivatives of xanthones with potential biological activity." Dissertação, 2019. https://hdl.handle.net/10216/124059.

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49

Martins, Márcia Sofia Silva. "Synthesis and neuroprotection studies of new xanthenes and fluorenes." Master's thesis, 2021. https://hdl.handle.net/10216/136714.

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Maddani, Mahagundappa R. "Chemistry Of Molybdenum Xanthate [Mo02(Et2NCS2)] : Applications In Organic Synthesis." Thesis, 2009. https://etd.iisc.ac.in/handle/2005/1000.

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Abstract:

The thesis entitled ‘Chemistry of molybdenum xanthate (MoO2[Et2NCS2]2): Applications in organic synthesis’ is presented in 4 chapters. Molybdenum (IV and VI) oxo-complexes are the subject of significant interest due to their functional and structural similarities with several molybdo-enzymes.1 Literature survey suggests that, molybdenum (VI as well as IV) xanthate2 1 resembles the active sites of various molybdo-enzymes. Therefore, in the present thesis, we are presenting our attempts directed towards exploiting molybdenum xanthate 1 in developing various useful methodologies. Figure 1:

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