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Journal articles on the topic 'T-cell subpopulations'

Author: Grafiati

Published: 10 March 2023

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1

Tian, Yamin, Seiichiro Kobayashi, Nobuhiro Ohno, et al. "Leukemic T Cells Are Specifically Enriched In a Unique CD3dimCD7low Subpopulation of CD4+ T Cells In Acute-Type Adult T Cell Leukemia." Blood 116, no. 21 (2010): 4144. http://dx.doi.org/10.1182/blood.v116.21.4144.4144.

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Abstract Abstract 4144 [Background] Adult T-cell leukemia (ATL) is a malignant disorder caused by human T-cell leukemia virus type I (HTLV-I). Morphological discrimination of leukemic cells from non-leukemic T cells is often difficult in ATL since ATL cells reveal morphological diversity except for typical “flower cells”. Although a study using CD3 gating in flow cytometry reported that ATL cells were distinguishable as a CD3low population from normal lymphocytes, these cells were not well characterised as ATL cells. Considering that defective expression of CD7 as well as CD3 is common in ATL

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2

Phillips, S. M., D. Walker, S. K. Abdel-Hafez, et al. "The immune response to Schistosoma mansoni infections in inbred rats. VI. Regulation by T cell subpopulations." Journal of Immunology 139, no. 8 (1987): 2781–87. http://dx.doi.org/10.4049/jimmunol.139.8.2781.

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Abstract These studies assess the roles of subpopulations of T lymphocytes in inducing and modulating resistance to Schistosoma mansoni. CDF rats were depleted of RT 7.1+ (anti-Pan-T), W3/25+ (anti-T helper/inducer), or OX8+ (anti-T suppressor) cells by the in vivo administration of monoclonal antibodies (mAb). The development of parasites and immunity to challenge by S. mansoni were compared with results in undepleted normal and congenitally athymic rats. Discrete subpopulations of T lymphocytes were adoptively transferred to ascertain effects upon parasite development and the protective immu

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3

Kanof, Marjorie E. "Purification of T Cell Subpopulations." Current Protocols in Immunology 00, no. 1 (1991): 7.3.1–7.3.5. http://dx.doi.org/10.1002/0471142735.im0703s00.

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4

Kubick, Norwin, Patrick C. Henckell Flournoy, Ana-Maria Enciu, Gina Manda, and Michel-Edwar Mickael. "Drugs Modulating CD4+ T Cells Blood–Brain Barrier Interaction in Alzheimer’s Disease." Pharmaceutics 12, no. 9 (2020): 880. http://dx.doi.org/10.3390/pharmaceutics12090880.

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The effect of Alzheimer’s disease (AD) medications on CD4+ T cells homing has not been thoroughly investigated. CD4+ T cells could both exacerbate and reduce AD symptoms based on their infiltrating subpopulations. Proinflammatory subpopulations such as Th1 and Th17 constitute a major source of proinflammatory cytokines that reduce endothelial integrity and stimulate astrocytes, resulting in the production of amyloid β. Anti-inflammatory subpopulations such as Th2 and Tregs reduce inflammation and regulate the function of Th1 and Th17. Recently, pathogenic Th17 has been shown to have a superior

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5

Leonhardt, U., U. Wagner, M. Werner, and L. Engelmann. "T-cell-subpopulations in septic patients." Critical Care 5, Suppl 1 (2001): P059. http://dx.doi.org/10.1186/cc1127.

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6

Ferrara, Andrea, Marvin M. McMillen, and Garth H. Ballantyne. "T-cell subpopulations and colorectal cancer." Diseases of the Colon & Rectum 33, no. 5 (1990): 367–69. http://dx.doi.org/10.1007/bf02156259.

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7

Abramova, A. V., I. V. Galtseva, E. A. Mikhailova, et al. "Oligoclonality and subpopulation structure of bone marrow T-cells in patients with aplastic anaemia." Russian journal of hematology and transfusiology 65, no. 4 (2020): 417–30. http://dx.doi.org/10.35754/0234-5730-2020-65-4-417-430.

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Introduction. The main pathogenetic mechanism of the development of aplastic anemia (AA) is a violation of the immune regulation of hematopoiesis.Aim: to study of the subpopulation composition of T-cells and the repertoire of the T-cell receptor in AA patients.Patients and Methods. The study included AA patients (n = 40) without prior immunosuppressive therapy in 2018–2020. The T-cell subpopulation structure and T-cell receptor Vβ-family (TCR-Vβ) oligoclonality were studied in samples of bone marrow using ﬂow cytometry.Results. We report characteristic properties of T-cell subpopulations of bo

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8

Hafler, D. A., D. A. Fox, D. Benjamin, and H. L. Weiner. "Antigen reactive memory T cells are defined by Ta1." Journal of Immunology 137, no. 2 (1986): 414–18. http://dx.doi.org/10.4049/jimmunol.137.2.414.

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Abstract Ta1 is a 105,000 dalton protein that is weakly expressed on a small fraction of resting human peripheral blood T cells but strongly expressed in vitro on T cell clones and a substantial proportion of activated T cells. Unlike receptors for growth factors such as IL 2, the Ta1 antigen is present on T cell lines and clones irrespective of cell cycle. The function of Ta1 was investigated after separation of T lymphocytes into Ta1-enriched and Ta1-depleted subpopulations that were obtained from normal human subjects. Although Ta1-enriched T cells constitute only 10 to 15% of the E rosette

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9

SKÖLD, RYTTER, IVARS, and CARDELL. "Characterization of Subpopulations of T-Cell Receptor Intermediate (TCRint) T Cells." Scandinavian Journal of Immunology 49, no. 6 (1999): 611–19. http://dx.doi.org/10.1046/j.1365-3083.1999.00535.x.

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10

Bertrand, F. E., L. G. Billips, G. L. Gartland, H. Kubagawa, and H. W. Schroeder. "The J chain gene is transcribed during B and T lymphopoiesis in humans." Journal of Immunology 156, no. 11 (1996): 4240–44. http://dx.doi.org/10.4049/jimmunol.156.11.4240.

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Abstract In mice and chickens, J chain appears to be expressed only in activated B cells and plasma cells. In humans, studies based mainly on transformed cells suggest that J chain expression may initiate during earlier stages in B lineage differentiation. In the present study, we isolated a series of hematopoietic subpopulations from human fetal and adult tissues by immunofluorescence cell sorting and examined each subpopulation for J chain expression by reverse transcriptase-PCR. In fetal and adult bone marrow, J chain transcripts were detected at all stages of B lineage differentiation, inc

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11

Baldwin, Cynthia, and Chuang Chen. "Gamma delta T cell subpopulations defined by expression of distinct sets of the co-receptor WC1 genes. (89.6)." Journal of Immunology 184, no. 1_Supplement (2010): 89.6. http://dx.doi.org/10.4049/jimmunol.184.supp.89.6.

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Abstract Gamma delta T cells can be 60% of peripheral blood mononuclear cells in young ruminants with the majority expressing the WC1 co-receptor. WC1 co-receptors are composed of up to eleven extracellular scavenger receptor (SRCR) domains with the interdomain pattern organized as a-[b-c-d-e-d’]-[b-c-d-e-d’] and the greatest differences occurring in the most distal domain 1 (‘a’ in the pattern). Two main subpopulations are defined by the presence of either the WC1.1 or the WC1.2-antigenic epitopes and these are functionally distinct since only a small subpopulation of WC1.1+ cells proliferate

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12

Katsura, Y., T. Amagai, T. Kina, T. Sado, and S. Nishikawa. "Two subpopulations of stem cells for T cell lineage." Journal of Immunology 135, no. 5 (1985): 3021–27. http://dx.doi.org/10.4049/jimmunol.135.5.3021.

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Abstract An assay system for the stem cell that colonizes the thymus and differentiates into T cells was developed, and by using this assay system the existence of two subpopulations of stem cells for T cell lineage was clarified. Part-body-shielded and 900-R-irradiated C57BL/6 (H-2b, Thy-1.2) recipient mice, which do not require the transfer of pluripotent stem cells for their survival, were transferred with cells from B10 X Thy-1.1 (H-2b, Thy-1.1) donor mice. The reconstitution of the recipient's thymus lymphocytes was accomplished by stem cells in the donor cells and those spared in the shi

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13

Tedder, T. F., M. D. Cooper, and L. T. Clement. "Human lymphocyte differentiation antigens HB-10 and HB-11. II. Differential production of B cell growth and differentiation factors by distinct helper T cell subpopulations." Journal of Immunology 134, no. 5 (1985): 2989–94. http://dx.doi.org/10.4049/jimmunol.134.5.2989.

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Abstract Two monoclonal antibodies (HB-10 and HB-11), which react with human T, B, and NK cells, identify approximately 50% of the Leu-3+ T helper (TH) cells in adult blood. In the present studies, the functional capabilities of the HB-11+ and HB-11-TH cell subpopulations were examined after purification by fluorescence-activated cell sorting. Both subpopulations proliferated in response to PHA, Con A, PWM, and OKT-3 antibodies. The HB-11+ TH cells gave a minimal proliferative response to soluble tetanus toxoid antigen, whereas HB-11-TH cells responded well. After mitogen activation, both HB-1

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14

Kim, Young-Hee, Tae-Young Jung, Shin Jung, et al. "Tumour-infiltrating T-cell subpopulations in glioblastomas." British Journal of Neurosurgery 26, no. 1 (2011): 21–27. http://dx.doi.org/10.3109/02688697.2011.584986.

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15

Haudebourg, Thomas, Nicolas Poirier, and Bernard Vanhove. "Depleting T-cell subpopulations in organ transplantation." Transplant International 22, no. 5 (2008): 509–18. http://dx.doi.org/10.1111/j.1432-2277.2008.00788.x.

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16

Eedy, D. J., D. Burrows, T. Clifford, and A. Fay. "Elevated T cell subpopulations in dental students." Journal of Prosthetic Dentistry 63, no. 5 (1990): 593–96. http://dx.doi.org/10.1016/0022-3913(90)90082-n.

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17

Salami, Falastin, Lampros Spiliopoulos, Marlena Maziarz, et al. "Long-Term GAD-alum Treatment Effect on Different T-Cell Subpopulations in Healthy Children Positive for Multiple Beta Cell Autoantibodies." Journal of Immunology Research 2022 (May 25, 2022): 1–17. http://dx.doi.org/10.1155/2022/3532685.

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Objective. The objective of this study was to explore whether recombinant GAD65 conjugated hydroxide (GAD-alum) treatment affected peripheral blood T-cell subpopulations in healthy children with multiple beta cell autoantibodies. Method. The Diabetes Prevention–Immune Tolerance 2 (DiAPREV-IT 2) clinical trial enrolled 26 children between 4 and 13 years of age, positive for glutamic acid decarboxylase autoantibody (GADA) and at least one other autoantibody (insulin, insulinoma antigen-2, or zinc transporter 8 autoantibody (IAA, IA-2A, or ZnT8A)) at baseline. The children were randomized to two

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Kalavska, Katarina, Zuzana Sestakova, Andrea Mlcakova, et al. "Detection of Specific Immune Cell Subpopulation Changes Associated with Systemic Immune Inflammation–Index Level in Germ Cell Tumors." Life 12, no. 5 (2022): 678. http://dx.doi.org/10.3390/life12050678.

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The tumor microenvironment (TME) and the host inflammatory response are closely interconnected. The interplay between systemic inflammation and the local immune response may influence tumor development and progression in various types of cancer. The systemic immune–inflammation index (SII) represents a prognostic marker for germ cell tumors (GCTs). The aim of the present study was to detect specific immune cell subpopulation changes which were associated with the SII level in chemotherapy-naïve GCT patients. In total, 51 GCT patients, prior to cisplatin-based chemotherapy, were included in the

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19

Witte, P. L., and J. W. Streilein. "Development and ontogeny of hamster T cell subpopulations." Journal of Immunology 137, no. 1 (1986): 45–54. http://dx.doi.org/10.4049/jimmunol.137.1.45.

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Abstract The Syrian hamster is unique among laboratory animals because products of class I MHC genes are monomorphic. Thus, this species may be a model in which to test the relationship between MHC polymorphism and the T cell antigen receptor repertoire. Recently, cytotoxic and helper T cell subpopulations have been distinguished on the basis of cell surface phenotype detected with monoclonal antibodies (mAb). We used these reagents (mAb 110 detects all peripheral T cells and mAb 38 detects cytotoxic T cells) to dissect and categorize thymic populations according to relative maturational statu

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20

Öbro, Nina Friesgaard, Lars Peter Ryder, Hans Ole Madsen, et al. "Intra-Tumoral Blast Heterogeneity and Implications for Minimal Residual Disease Detection in T-Cell Acute Lymphoblastic Leukemia." Blood 124, no. 21 (2014): 1076. http://dx.doi.org/10.1182/blood.v124.21.1076.1076.

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Abstract Introduction:The early treatment response, measured as minimal residual disease (MRD), is the most important tool for treatment stratification in T-cell acute lymphoblastic leukemia (T-ALL). Flow cytometry-based MRD (Flow-MRD) monitoring, in addition to the PCR-MRD method, is often important to ensure a sensitive MRD marker. Additionally, Flow-MRD investigation may add biological information to the MRD result itself, and allow cell sorting for biological and functional analyses. Flow-MRD in T-ALL consists of identification of cells with immature T-cell phenotype in bone marrow. Howeve

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21

Deveci, Figen, H. Handan Akbulut, Ilhami Celik, M. Hamdi Muz, and Fulya İlhan. "Lymphocyte Subpopulations in Pulmonary Tuberculosis Patients." Mediators of Inflammation 2006 (2006): 1–6. http://dx.doi.org/10.1155/mi/2006/89070.

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Protection againstMycobacterium tuberculosisis based on cell-mediated immunity, most importantly involvingCD4+andCD8+T-cell subsets. The aim of this study was to evaluateCD4+andCD8+T-cell profiles andCD19+andCD3-CD(16+56)+populations in patients with pulmonary tuberculosis.CD4+andCD8+T cells, B-lymphocytes, and natural killer (NK) cells were evaluated in 75 active (APTB) and 25 inactive (IPTB) pulmonary tuberculosis cases and 20 healthy subjects (HCs). The results were compared at different stages of antituberculosis treatment in the APTB patients and also according to X-ray findings in the ne

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22

Cox, Charlotte Victoria, Paraskevi Diamanti, and Allison Blair. "Assessing CD97 and CD99 As Markers of Leukaemia Initiating Cells in Paediatric ALL." Blood 120, no. 21 (2012): 1882. http://dx.doi.org/10.1182/blood.v120.21.1882.1882.

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Abstract Abstract 1882 Overall survival rates in paediatric acute lymphoblastic leukaemia (ALL) have dramatically improved but around 20% do not respond to current therapies and subsequently relapse. Leukaemia initiating cells (LIC) are the topic of much investigation, as these cells can self-renew and may have the potential to cause relapse. It has been shown that multiple subpopulations of ALL cells have the ability to initiate the disease in immune deficient mouse models. Therefore, treatment should be targeted at all cells with this capacity, if the disease is to be eradicated. Minimal res

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Tupitsyn, N. N., T. M. Dzhumanazarov, A. D. Palladina, A. K. Alakhverdiyev, S. V. Chulkova, and P. V. Kononets. "IMMUNOLOGICAL PARAMETERS OF BONE MARROW IN NON-SMALL CELL LUNG CANCER." Russian Journal of Biotherapy 19, no. 2 (2020): 47–54. http://dx.doi.org/10.17650/1726-9784-2019-19-2-47-54.

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Introduction Generation of most immunocompetent cells takes place in bone marrow Bone marrow. As well, bone marrow is a peripheral lymphoid organ where antitumor effector cells and memory cells are present. The aim of the work is to estimate peripheral lymphoid cell subpopulations in bone marrow of lung cancer patients. Materials and methods Study has been done in 68 pts with lung cancer: squamous cell cancer (n = 28), adenocarcinoma (n = 38), other forms (n = 2). In all cases standard diagnostic and staging procedures were performed, as well as morphological (myelogram) and immunological stud

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Chen, Z. W., Z. C. Kou, C. Lekutis, et al. "T cell receptor V beta repertoire in an acute infection of rhesus monkeys with simian immunodeficiency viruses and a chimeric simian-human immunodeficiency virus." Journal of Experimental Medicine 182, no. 1 (1995): 21–31. http://dx.doi.org/10.1084/jem.182.1.21.

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Changes in T cell receptor (TCR) V beta repertoire and their correlation with virologic events were investigated in rhesus monkeys after acute infection with the simian immunodeficiency virus (SIV). 11 genetically defined rhesus monkeys were experimentally infected with SIVmac or a chimeric simian-human immunodeficiency virus (SHIV), and their peripheral blood lymphocytes (PBL) and lymph nodes were prospectively assessed for TCR V beta gene expression. PBL and lymph nodes of the acutely infected monkeys demonstrated an expansion of selected V beta-expressing T lymphocyte subpopulations as earl

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Riggs, J. E., A. M. Lussier, S. K. Lee, M. C. Appel, and R. T. Woodland. "Differential radiosensitivity among B cell subpopulations." Journal of Immunology 141, no. 6 (1988): 1799–807. http://dx.doi.org/10.4049/jimmunol.141.6.1799.

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Abstract We have previously shown that low doses of ionizing radiation selectively impair a functionally defined B cell subpopulation. Normal mice, after exposure to 200 rad of ionizing radiation, have normal or near normal splenic plaque-forming cell responses to thymus-independent type 1 Ag, but reduced responses to thymus-independent type 2 Ag. Here, we confirm and extend the original findings by using hapten-specific serum RIA to demonstrate this differential radiosensitivity is systemic. We also examined splenocytes stained with a panel of lymphocyte surface Ag by FACS analysis to determi

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Bohana-Kashtan, Osnat, Hyam Levitsky, and Curt I. Civin. "Identification of New Alloantigen-Reactive CD8+ Cytotoxic and Suppressor T Cell Subpopulations." Blood 110, no. 11 (2007): 3229. http://dx.doi.org/10.1182/blood.v110.11.3229.3229.

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We sought to develop a better understanding of the T cells involved in the human allogeneic immune response, in order to eventually engineer a donor graft with reduced GVHD-mediating potential, without ablating general immune competence. Prior studies reported that all the activated CD4+ T cells responding to a specific antigen challenge reside within the CD4high population expressing high levels of membrane CD4. We identified a new population of activated CD8+ T cells that developed during an in vitro allogeneic immune response, along with the allo-activated CD4high T cell population. Analogo

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Patrushev, Alexander V., Alexey V. Samtsov, Vladimir Yu Nikitin, Alexey V. Soukharev, Oksana P. Gumilevskaya, and Irina A. Sukhina. "Assessment of CLA+T-cell subpopulations in the blood of patients with chronic dermatoses." Vestnik dermatologii i venerologii 96, no. 4 (2020): 22–31. http://dx.doi.org/10.25208/vdv1155-2020-96-4-22-31.

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Background. CLA+T-cell are an important component of skin-associated lymphoid tissue, and thus determine the pathogenesis of many immuno-mediated dermatoses. Aims. Determine the relative number of CLA+T-cell subpopulations in the peripheral blood of patients with psoriasis, lichen planus and atopic dermatitis, as well as assess their impact on the severity of dermatoses. Materials and methods. We examined 82 patients with psoriasis aged 19 to 62 years, 54 patients with lichen planus (LP) aged 18 to 54 years, 44 patients with atopic dermatitis (AD) aged 18 to 44 years, as well as 20

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Fyfe, G., J. A. Cebra-Thomas, E. Mustain, J. M. Davie, C. D. Alley, and M. H. Nahm. "Subpopulations of B lymphocytes in germinal centers." Journal of Immunology 139, no. 7 (1987): 2187–94. http://dx.doi.org/10.4049/jimmunol.139.7.2187.

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Abstract With two new monoclonal antibodies and flow cytometry, we defined three subpopulations among B cells expressing binding sites for peanut agglutinin (i.e., B cells of the germinal center). On monoclonal antibody (5B5) binds globotriaosyl ceramide. The B lymphocytes binding 5B5 have binding sites for peanut agglutinin on the surface and express only small amounts of sIgD and sIgM. When tested against a panel of B cell lines, only Burkitt's lymphoma cells were 5B5+. Moreover, the 5B5+ cells have larger average sizes and a large fraction of proliferating cells. The other monoclonal antibo

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McLendon, Bryan A., Heewon Seo, Avery C. Kramer, Robert C. Burghardt, Fuller W. Bazer, and Greg A. Johnson. "Pig conceptuses secrete interferon gamma to recruit T cells to the endometrium during the peri-implantation period†." Biology of Reproduction 103, no. 5 (2020): 1018–29. http://dx.doi.org/10.1093/biolre/ioaa132.

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Abstract The emerging paradigm in the immunology of pregnancy is that implantation of conceptuses does not progress in an immunologically suppressed environment. Rather, the endometrium undergoes a controlled inflammatory response during implantation as trophectoderm of elongating and implanting pig conceptuses secrete the pro-inflammatory cytokine interferon gamma (IFNG). Results of this study with pigs revealed: (1) accumulation of immune cells and apoptosis of stromal cells within the endometrium at sites of implantation during the period of IFNG secretion by conceptuses; (2) accumulation o

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Savchenko, Andrey, Aleksandr Borisov, Igor Kudryavtsev, and Anton Moshev. "RELATIONSHIP OF THE T-REGULATORY CELLS NUMBER WITH THE CYTOTOXIC T-LYMPHOCYTES AND NKT-CELLS LEVELS IN PATIENTS WITH RENAL CANCER." Problems in oncology 63, no. 1 (2017): 104–9. http://dx.doi.org/10.37469/0507-3758-2017-63-1-104-109.

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The aim of the study was to investigate the features of the relation to the number and the phenotype of the cytotoxic T-lymphocytes and NKT-cell from regulatory T-cells content in the blood by patients with renal cell carcinoma. The study included patients with renal cell carcinoma (T3N0M0, clear cell type) at the age of 40-55 years before surgery. Lymphocyte immunophenotyping was performed by flow cytometry. It is found that in the peripheral blood of the patients with renal cell carcinoma accompanied by increased number of T-regulatory cells observed decrease content of the cytotoxic T-lymph

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Risley, Christopher A., Christopher D. Scharer, Jeremy M. Boss, and Frances E. Lund. "T-bet expression marks a transcriptionally and functionally distinct population of memory B cells." Journal of Immunology 206, no. 1_Supplement (2021): 114.18. http://dx.doi.org/10.4049/jimmunol.206.supp.114.18.

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Abstract Memory B cells (Bmem) rapidly differentiate and mount antibody (Ab) responses to previously encountered antigen (Ag). Mouse Bmem can be subdivided using BCR isotype or expression of CD73, CD80, and PD-L2. Many of these Bmem populations were discovered following vaccination with alum-adjuvanted Ag, which drives a distinct immune response from those generated after infection with IFN-inducing viruses. We previously demonstrated that the IFNγ-inducible transcription factor T-bet is required for Bmem recall responses to influenza but not nematode infections, suggesting that T-bet might re

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Coser, Lilian de O., Lívia M. Genaro, Amauri S. Justo-Junior, et al. "Evaluation of CD8+ T cell subpopulations in paracoccidioidomycosis." Future Microbiology 16, no. 13 (2021): 977–85. http://dx.doi.org/10.2217/fmb-2020-0261.

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Aim: We aimed to verify the frequency of CD8+ T cell subsets in patients with acute form and chronic form of paracoccidioidomycosis. Material & Methods: Mononuclear cells from paracoccidioidomycosis patients and healthy donors were isolated and phenotyped by flow cytometry. Dendritic cells were pulsed with Paracoccidioides brasiliensis yeast and co-cultures with lymphocytes. Cytokine production was measured by ELISA. Results: Acute form patients present a higher frequency of Tc1 and Tc10 cells, while chronic form patients have more Tc1 and Tc21 cells, compared with healthy controls. In vit

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Bhondeley, Manoj K., Raj D. Mehra, Narinder K. Mehra, et al. "Imbalances in T cell subpopulations in human gliomas." Journal of Neurosurgery 68, no. 4 (1988): 589–93. http://dx.doi.org/10.3171/jns.1988.68.4.0589.

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✓ The quantitation of cells bearing CD3, CD4, CD8, and B cell phenotypic markers, as well as an estimation of serum immunoglobulin (Ig)G, IgA, and IgM, was carried out in a group of 39 glioma patients with different grades of malignancy. The findings were compared with those obtained from 21 normal healthy control subjects. The analysis revealed a significant decrease both in the absolute numbers and in the percentages of circulating CD3+ (p < 0.001) and CD4+ (p < 0.001) cells, while the CD8+ and Pan B+ cells remained within the normal range irrespective of the type and grade of tumor. T

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Lascurain, Ricardo, Flor Porras, Renata Báez, et al. "Amaranthus leucocarpusLectin Recognizes Human Naive T Cell Subpopulations." Immunological Investigations 26, no. 5-7 (1997): 579–87. http://dx.doi.org/10.3109/08820139709088542.

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35

&NA;. "BCG vaccinations in neonates affect T-cell subpopulations." Inpharma Weekly &NA;, no. 1520 (2006): 20. http://dx.doi.org/10.2165/00128413-200615200-00052.

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FISHWILD, DIANNEE, and EDGAR G. ENGLEMAN. "Human T-Cell Subpopulations Distinguished by Monoclonal Antibodies." International Ophthalmology Clinics 25, no. 2 (1985): 55–62. http://dx.doi.org/10.1097/00004397-198502520-00008.

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Gunduz, Kamer, Gunseli Ozturk, Ender Terzioglu, and Filiz Sebik. "T Cell Subpopulations and IL-2R in Vitiligo." Journal of Dermatology 31, no. 2 (2004): 94–97. http://dx.doi.org/10.1111/j.1346-8138.2004.tb00514.x.

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HOLEN, E., та S. ELSAYED. "Effects of β2adrenoceptor agonists on T-cell subpopulations". APMIS 106, № 7-12 (1998): 849–57. http://dx.doi.org/10.1111/j.1699-0463.1998.tb00231.x.

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Essunger, Paulina, and Alan S. Perelson. "Modeling HIV Infection of CD4+ T-cell Subpopulations." Journal of Theoretical Biology 170, no. 4 (1994): 367–91. http://dx.doi.org/10.1006/jtbi.1994.1199.

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Achiron, A., M. Mendel, G. Rechavi, B. Ramot, and E. Melamed. "Changes in T-cell subpopulations in multiple sclerosis." Annals of Neurology 26, no. 2 (1989): 291–92. http://dx.doi.org/10.1002/ana.410260224.

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Mozzanica, Nino, Ugo Frigerio, Aldo F. Finzi, et al. "T cell subpopulations in vitiligo: A chronobiologic study." Journal of the American Academy of Dermatology 22, no. 2 (1990): 223–30. http://dx.doi.org/10.1016/0190-9622(90)70029-h.

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Deuse, T., H. Reichenspurner, R. C. Robbins, and S. Schrepfer. "236: Immunosuppressive Agents Differently Suppress T Cell Subpopulations." Journal of Heart and Lung Transplantation 29, no. 2 (2010): S81. http://dx.doi.org/10.1016/j.healun.2009.11.247.

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Menzel, E. J., G. J. Zlabinger, A. Dunky, and C. Steffen. "Autoimmunity and T-cell subpopulations in old age." Archives of Gerontology and Geriatrics 7, no. 4 (1988): 249–60. http://dx.doi.org/10.1016/0167-4943(88)90008-8.

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Lecolier, B., S. Marion, F. Derouin, F. Daffos, and G. Sarrot. "T-cell subpopulations of fetuses infected byToxoplasma gondii." European Journal of Clinical Microbiology & Infectious Diseases 8, no. 6 (1989): 572–73. http://dx.doi.org/10.1007/bf01967488.

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Sata, Fumihiro, Shunichi Araki, Takeshi Tanigawa, et al. "Changes in T Cell Subpopulations in Lead Workers." Environmental Research 76, no. 1 (1998): 61–64. http://dx.doi.org/10.1006/enrs.1997.3790.

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Bacchus-Souffan, Charline, Mark Fitch, Jori Symons, et al. "Relationship between CD4 T cell turnover, cellular differentiation and HIV persistence during ART." PLOS Pathogens 17, no. 1 (2021): e1009214. http://dx.doi.org/10.1371/journal.ppat.1009214.

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The precise role of CD4 T cell turnover in maintaining HIV persistence during antiretroviral therapy (ART) has not yet been well characterized. In resting CD4 T cell subpopulations from 24 HIV-infected ART-suppressed and 6 HIV-uninfected individuals, we directly measured cellular turnover by heavy water labeling, HIV reservoir size by integrated HIV-DNA (intDNA) and cell-associated HIV-RNA (caRNA), and HIV reservoir clonality by proviral integration site sequencing. Compared to HIV-negatives, ART-suppressed individuals had similar fractional replacement rates in all subpopulations, but lower a

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Damani-Yokota, Payal, Jancie C. Telfer та Cynthia L. Baldwin. "Variegated expression of members of the WC1 pathogen recognition receptor and co-receptor multi-gene family on γδ T cells". Journal of Immunology 196, № 1_Supplement (2016): 216.22. http://dx.doi.org/10.4049/jimmunol.196.supp.216.22.

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Abstract Cells of the immune system recognize disease-causing pathogens and respond in a manner to stop the infection. While we know how conventional cells of the immune system do this, for some non-conventional cells such as γδ T cells this process is less clear. We have shown that bovine γδ T cells bear lineage-specific transmembrane glycoproteins, known as WC1, are coded by a multigenic family and that these molecules function both as pattern recognition receptors (PRR) and signaling co-receptors for cellular activation. For example, while a subpopulation known as WC1.1+ γδ T cells respond

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Levy, Shoshana, and Yael Sagi. "Complementary Costimulation of Human T Cell Subpopulations by CD28 and CD81." Blood 118, no. 21 (2011): 1124. http://dx.doi.org/10.1182/blood.v118.21.1124.1124.

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Abstract Abstract 1124 CD81 is a widely expressed tetraspanin molecule that physically associates with CD4 and CD8 on the surface of human T cells. Coengagement of CD81 and CD3 results in the activation and proliferation of T cells. CD81 also costimulated mouse T cells that lack CD28, suggesting either a redundant or a different mechanism of action. Here we show that CD81 and CD28 have a preference for different subsets of T cells - primary human naïve T cells are better costimulated by CD81, while the memory T cell subsets and Tregs are better costimulated by CD28. The more efficient activat

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Kou, Zhong Chen, Joshua S. Puhr, Mabel Rojas, Wayne T. McCormack, Maureen M. Goodenow та John W. Sleasman. "T-Cell Receptor Vβ Repertoire CDR3 Length Diversity Differs within CD45RA and CD45RO T-Cell Subsets in Healthy and Human Immunodeficiency Virus-Infected Children". Clinical Diagnostic Laboratory Immunology 7, № 6 (2000): 953–59. http://dx.doi.org/10.1128/cdli.7.6.953-959.2000.

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ABSTRACT The T-cell receptor (TCR) CDR3 length heterogeneity is formed during recombination of individual Vβ gene families. We hypothesized that CDR3 length diversity could be used to assess the fundamental differences within the TCR repertoire of CD45RA and CD45RO T-cell subpopulations. By using PCR-based spectratyping, nested primers for all 24 human Vβ families were developed to amplify CDR3 lengths in immunomagnetically selected CD45RA and CD45RO subsets within both CD4+ and CD8+ T-cell populations. Umbilical cord blood mononuclear cells or peripheral blood mononuclear cells obtained from

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Farace, F., F. Orlanducci, P. Y. Dietrich, et al. "T cell repertoire in patients with B chronic lymphocytic leukemia. Evidence for multiple in vivo T cell clonal expansions." Journal of Immunology 153, no. 9 (1994): 4281–90. http://dx.doi.org/10.4049/jimmunol.153.9.4281.

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Abstract To characterize circulating T cell subpopulations in B chronic lymphocytic leukemia patients, TCR V alpha and V beta gene-segment use was analyzed by PCR using a panel of V gene-segment subfamily-specific oligonucleotide primers (V alpha 1-29/V beta 1-24). Virtually all V alpha and V beta subfamily specificities were expressed in these patients (nine stage A and four stage C), and the mean values obtained for each specificity were similar to those of a group of 13 healthy donors. Nonetheless, individual analysis revealed that unique V alpha or V beta gene-segment transcripts were over

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