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Dissertations / Theses on the topic 'T3 (Triiodothyronine)'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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1

PULIGA, ELISABETTA. "POTENTIAL THERAPEUTIC USE OF TRIIODOTHYRONINE (T3) IN HEPATOCELLULAR CARCINOMA." Doctoral thesis, Università degli Studi di Cagliari, 2018. http://hdl.handle.net/11584/255968.

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Hepatocellular carcinoma (HCC) is the most common primary malignancy of the liver with a poor prognostic outcome due to limited and ineffective therapeutic strategies. Thus, it is mandatory to develop more efficient and powerful treatments for this aggressive tumor. Recent studies have suggested the possible role of local hypothyroidism in HCC development, in both humans and rodents. Previous observations from our laboratory showed that 1-week exogenous administration of triiodothyronine (T3) induced the regression of preneoplastic hepatic nodules generated by the Resistant Hepatocyte (RH) mod

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2

Boertje, Ethan Thomas. "Testosterone (T) and Triiodothyronine (T3) in Franklin’s Gull (Leucophaeus Pipixcan) Eggs." Thesis, North Dakota State University, 2018. https://hdl.handle.net/10365/28720.

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Maternally-derived hormones are known to influence the growth and development of offspring. The differential deposition of these maternally-derived hormones into egg yolk is one way by which females can alter and impact their chicks’ survival. Yolk constituents, especially testosterone, have been described for a wide variety of species. However, few studies have focused on multiple maternally-derived hormones regulated by independent axis in the endocrine system, these of which have mainly focused on corticosterone and testosterone. We determined within and among female variation in testostero

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3

Boertje, Ethan Thomas. "Testosterone (T) and Triiodothyronine (T3) in Franklin?s Gull (Leucophaeus Pipixcan) Eggs." Thesis, North Dakota State University, 2018. https://hdl.handle.net/10365/28720.

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Maternally-derived hormones are known to influence the growth and development of offspring. The differential deposition of these maternally-derived hormones into egg yolk is one way by which females can alter and impact their chicks? survival. Yolk constituents, especially testosterone, have been described for a wide variety of species. However, few studies have focused on multiple maternally-derived hormones regulated by independent axis in the endocrine system, these of which have mainly focused on corticosterone and testosterone. We determined within and among female variation in testostero

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4

LOZANO, FREDERIC. "Fonction thyroidienne et depression : revue de la litterature, syndrome de basse t3 a propos d'une etude chez 54 patients." Besançon, 1994. http://www.theses.fr/1994BESA3108.

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5

Gražienė, Aleksandra. "Padidėjusio laisvo trijodtironino poveikio ypatumai, esant normaliai tirotropinio hormono ir laisvo tiroksino koncentracijai." Doctoral thesis, Lithuanian Academic Libraries Network (LABT), 2012. http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2012~D_20120918_151340-85920.

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Įtariant skydliaukės patologiją rekomenduojama tirti tirotropinio hormono ir laisvo tiroksino koncentracijas kraujo serume. Laisvo trijodtironino tyrimas nėra įprastinis ir atliekamas kai nustatoma sumažėjusi tirotropinio hormono ir normali laisvo tiroksino koncentracija. Šio darbo tikslas - įvertinti padidėjusio laisvo trijodtironino poveikio ypatumus, esant normaliai tirotropinio hormono ir laisvo tiroksino koncentracijai. Uždaviniai – nustatyti ir įvertinti klinikinių simptomų ypatumus, objektyvaus tyrimo duomenis (odos būklę, skydliaukės padidėjimo laipsnį, širdies ir kraujagyslių sistemos

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6

Rodier, Anne. "Etude de l'expression et de la localisation de la protéine BTG1 dans les myoblastes aviaires. Régulation par la T3 et implication dans la myogénèse." Montpellier 1, 1999. http://www.theses.fr/1999MON1T011.

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7

Marchal, Sophie. "Influence de la triiodothyronine (T3) sur la différenciation des myoblastes aviaires ; implications de la voie AMPc ; mécanismes d'action." Montpellier 1, 1995. http://www.theses.fr/1995MON1T034.

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8

Moor, Andrea Nichole. "The in vivo and in vitro effects of 3,5,3'-triiodothyronine (T3) on control and mdx muscle cell proliferation." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp04/nq23641.pdf.

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9

BURY, FABIENNE. "Modulation in vitro de l'expression de la proteine basique encephalitogene de la myeline par la l-3, 5, 3 - triiodothyronine (t3) et distribution des isoformes du recepteur de t3 dans l'encephale du mutant dysmyelinique jimpy." Université Louis Pasteur (Strasbourg) (1971-2008), 1999. http://www.theses.fr/1999STR13236.

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L'objectif de ce travail etait de determiner l'action de la triidothyronine (t3) sur les proteines basiques (mbp) des oligodendrocytes (ol) responsables de la formation des gaines de myeline du systeme nerveux central (snc), lorsque ces cellules sont cultivees en presence de neurones ou d'astrocytes. Le mode d'action de t3 passe par une interaction avec des recepteurs nucleaires specifiques. Trois sont fonctionnels (rt31, rt31, rt32) et rt32 qui ne fixe pas t3 est un antagoniste des rt3 1 et. Leur expression distincte au cours de l'ontogenese du snc suggere des fonctions specifiques et donc la

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10

Busson, Muriel. "Etude de l'implication de la protéine antiproliférative BTG1 dans la régulation de la différenciation des myoblastes aviaires par la T3." Montpellier, ENSA, 2004. http://www.theses.fr/2004ENSA0010.

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Le gène BTG1 a été identifié lors du clonage d’un point de translocation chromosomique dans un cas de leucémie lymphocytaire chronique des cellules B. Son produit appartient à une famille de protéines antiprolifératives. Les travaux de notre équipe ont établi que la T3 induit indirectement l’expression de ses transcrits à confluence cellulaire et stimule son import nucléaire dans les myoblastes aviaires. En outre, BTG1 reproduit les effets myogéniques de la T3 : stimulation de la sortie des myoblastes du cycle cellulaire et de leur différenciation terminale. Dans ce travail, nous avons étudié

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11

Olímpio, Regiane Marques Castro. "Efeito da triiodotironina (T3) e estrógeno (E2) Sobre a expressão gênica e proteica de Rankl, OPG E c-Fos em osteoblastos derivados de células tronco mesenquimais humanas." Botucatu, 2017. http://hdl.handle.net/11449/151414.

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Orientador: Célia Regina Nogueira<br>Resumo: O tecido ósseo é extremamente complexo e regulado por fatores sistêmicos e locais, apresentando considerável atividade metabólica que envolve a remoção do osso mineralizado pelos osteoclastos, seguida pela formação da matriz óssea pelos osteoblastos. A associação de triiodotironina (T3) e estrógeno (E2) pode levar a uma resposta complexa à atividade do tecido ósseo sendo que o T3 possui efeito tanto sobre a reabsorção como na formação óssea e o E2, em baixo nível, pode levar a osteoporose e no estado normal garante a supressão de citocinas, a partir

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12

Ract, Erika Lia Brunetto. "Participação da triiodotironina (T3) na regulação da expressão de genes em cardiomiócitos de ratos : estudos in vivo e in vitro." Universidade de São Paulo, 2011. http://www.teses.usp.br/teses/disponiveis/42/42137/tde-19032012-133606/.

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Os hormônios tireoidianos (HTs) promovem suas ações através de mecanismos genômicos, porém, há inúmeras evidências de que o HT também promove efeitos que ocorrem em curto espaço de tempo (poucos minutos), e que independem de, as quais são conhecidas como ações não genômicas ou extranucleares. É sabido que, na insuficiência cardíaca ocorre uma menor expressão dos receptores nucleares de T3, o que reduz em muito os efeitos cardioestimulantes deste hormônio, sendo muito vantajoso numa situação de contenção energética. Assim, o presente estudo visa avaliar o efeito agudo (não genômico) da administ

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13

KOWALIK, MARTA ANNA. "Effect of the ligands of thyroid hormone receptor on non-alcoholic fatty liver disease." Doctoral thesis, Università degli Studi di Cagliari, 2009. http://hdl.handle.net/11584/266003.

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The term non-alcoholic fatty liver disease (NAFLD) has been used as a general name for conditions ranging from simple steatosis to steatohepatitis, advanced fibrosis and cirrhosis. End-stage NAFLD cirrhosis carries a substantial risk for early hepatocellular carcinoma development. Therefore, there is an increasing need for new therapeutic approaches for the treatment of this liver disease. Here, we examined the effect of the thyroid hormone triiodothyronine (T3) and the agonist of the thyroid hormone receptor β isoform (TRβ), GC-1, on fatty liver and steatohepatitis induced in rodents by a cho

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14

Augellone, Gabriella. "The effect of 3,5,3'-triiodothyronine (T3) on the early stages of colon carcinogenesis and tissue lipid composition." 1992. http://hdl.handle.net/1993/17440.

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15

Decker, Andrea H. "Associations between Butylparaben and Thyroid Levels in Females Aged 12 and over (NHANES, 2007-2008)." 2015. http://scholarworks.gsu.edu/iph_theses/370.

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Background: Paraben exposure occurs everyday to most people unknowingly. Parabens are present in most personal care products in varying amounts. Presently, parabens are not listed as endocrine disruptors; however, some research has shown parabens associated with decreases in thyroid hormone levels. The chemical and adsorption mechanism for parabens in association with thyroid hormones is not well understood. Determining whether parabens are associated with a change in thyroid hormone levels can help reduce the incidence of possible adverse health effects with exposure to parabens. Methodology:

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16

Martel, Caroline. "Localisation et caractérisation d'un élément de réponse à la triiodothyronine (T3) dans la partie promotrice du gène de la synthétase des acides gras (FAS) chez l'oie." Mémoire, 2006. http://www.archipel.uqam.ca/1730/1/M9252.pdf.

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L'obésité est maintenant perçue comme un problème de santé majeur dans notre société. C'est pourquoi la compréhension des mécanismes moléculaires liés au développement de cette maladie est primordiale. Des études comparatives entre des poulets de lignées grasses et des poulets de lignées maigres ont montré que la lipogénèse hépatique était plus élevée chez les animaux gras. La Synthétase des Acides Gras (FAS) est connue comme étant responsable de la synthèse des lipides saturés à longues chaînes. Des études antérieures ont démontré que ce gène est régulé à la fois par l'état nutritionnel et ho

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17

Gonçalves, Alexandre Manuel Monteiro. "T3 HORMONE AS AN EFFECTIVE THERAPY FOR HEART FAILURE WITH PRESERVED EJECTION FRACTION: Effects on Ca2+ transients and contractility." Master's thesis, 2018. http://hdl.handle.net/10316/81936.

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Dissertação de Mestrado em Investigação Biomédica apresentada à Faculdade de Medicina<br>A insuficiência cardíaca com fração de ejeção preservada (ICFEP) constitui um frequente problema clínico, mas até hoje, nenhuma intervenção terapêutica parece modular o seu desfecho clínico. Alguns doentes com ICFEP possuem alterações no eixo hormonal da tiroide e é já conhecido o impacto da influência destas hormonas sobre o sistema cardiovascular. Neste projeto, testamos a hipótese de que administração oral preventiva com triiodotironina (T3) pode prevenir o desenvolvimento de ICFEP. Iniciou-se às 14 sem

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18

BURLEOVÁ, Barbora. "Postnatální změny koncentrace hormonů štítné žlázy jehňat." Master's thesis, 2013. http://www.nusl.cz/ntk/nusl-154804.

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The aim of my work was to monitor and valorize of postnatal dynamics of thyroid hormones, thyroxine (TT4), triiodothyronine (TT3) and its free fractions (FT3 and FT4), in lambs up to 60 days of age. During the experiment 26 lambs were devided into two groups according to sex and were supplemented by iodine in concentration 0,7 ? 5 mg. Standard directed day ration for sheep is average 0,3 mg of iodine in 1 kilogram of dry mass (DM). One of the groups was also supplemented by selenium in concentration 0,2 ? 0,4 mg in 1 kilogram of DM.

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