Relevant bibliographies by topics / Tail flick method

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Academic literature on the topic 'Tail flick method'

Author: Grafiati
Published: 3 June 2025
Last updated: 31 July 2025

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Journal articles on the topic "Tail flick method"

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Carstens, E., and C. Wilson. "Rat tail flick reflex: magnitude measurement of stimulus-response function, suppression by morphine and habituation." Journal of Neurophysiology 70, no. 2 (1993): 630–39. http://dx.doi.org/10.1152/jn.1993.70.2.630.

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1. To quantitatively investigate a nocifensive behavioral response, we developed a method to measure the magnitude of the rat's tail flick reflex and its modulation. A radial array of force transducers measured forces of tail flicks (in rostral, horizontal, and vertical planes) elicited by graded noxious radiant thermal stimulation of the conscious rat's tail, from which the overall movement vector was calculated. 2. The rostrally directed component of tail flicks was always larger than dorsal or horizontal components; the latter was usually in a preferred (left or right) direction regardless
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Monisha, VM, Anshuman Trigunayat, and Anuradha Roy. "Analgesic and anti-anxiety activity of two Ayurvedic formulations (Rasnadi ksheerapaka and Sahacharadi taila) on experimental rat models." Journal of Ayurvedic and Herbal Medicine 8, no. 4 (2022): 221–27. http://dx.doi.org/10.31254/jahm.2022.8402.

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Background: Rasnadi ksheerapaka and Sahacharadi taila are known to be effective in shula and vatavyadhi and used very frequently in conditions involving pain. Aims and objective: To evaluate the analgesic and anti-anxiety activity of Rasnadi ksheerapaka and Sahacharadi taila matrabasti in Charles Foster Albino rats. Materials and method: For evaluation of analgesic study tail flick response in tail flick test and paw licking response in Eddy’s hot plate test was performed. Anti-anxiety study was conducted with elevated plus maze and open field maze. Result and conclusion: After both the experi
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Kava, T. V., and O. E. Yadlovskiy. "Tail-flick-est – aspects use in pharmacological researches." Farmatsevtychnyi zhurnal, no. 1-2 (August 14, 2018): 61–67. http://dx.doi.org/10.32352/0367-3057.1-2.18.07.

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The adequate assessment of anti-nociceptive activity is important. This is necessary for development of new analgesics that exceed effectiveness and/or safety of existing analgesics, fundamental research, study specifics pharmacodynamics of known analgesics.
 Рurpose of work is scientific and methodical analyze approaches to study of antinociceptive activity with Tail-flick test.
 The study was carried out using databases on the Internet using science-based databases: PubMed, Medline, Europe PMC, FDA, EMA, Google Scholar. Methods of approach to planning, conducting an experiment, int
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R., Sudar Codi, Sumina ., Uma N., and Manimekalai K. "Evaluation of opioid sparing effect of dexmedetomidine and pregabalin using acute pain model in male wistar rats." International Journal of Basic & Clinical Pharmacology 8, no. 8 (2019): 1911. http://dx.doi.org/10.18203/2319-2003.ijbcp20193201.

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Background: Adjuvant analgesics are added to pain management regimen to reduce opioid consumption and minimise their side effect. Newer ones like dexmedetomidine and pregabalin have not been thoroughly researched. Objectives of the study to study the opioid sparing effect of dexmedetomidine and pregabalin using tail flick and hot plate method in male wistar rats.Methods: Forty two rats were grouped into seven groups with six in each group. Analgesic activity was tested using tail flick, where in the reaction time to flick its tail on a heated surface was noted. In the hot plate method, the rea
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Delisma, Cici, Sri Peni Fitrianingsih, and Suwendar Suwendar. "UJI AKTIVITAS ANALGETIKA EKSTRAK n-HEKSANA DAUN AFRIKA (Vernonia amygdalina Delile) TERHADAP MENCIT SWISS WEBSTER JANTAN." Jurnal Ilmiah Farmasi Farmasyifa 1, no. 1 (2017): 26–34. http://dx.doi.org/10.29313/jiff.v1i1.3109.

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ABSTRAKNyeri merupakan persepsi sensorik mengganggu yang dapat ditangani dengan analgetika. Daun afrika (Vernonia amygdalina Delile) secara tradisional digunakan untuk mengobati nyeri seperti sakit gigi. Tujuan penelitian ini untuk menentukan aktivitas analgetika ekstrak n-heksana daun afrika dengan 2 metode pengujian dan menentukan dosis efektifnya. Metode Tail Flick Test untuk menguji aktivitas analgetika sentral dan metode Writhing Test untuk menguji aktivitas analgetika perifer. Mencit dibagi ke dalam 5 kelompok. Kelompok kontrol yang diberi CMC Na, kelompok uji yang diberi ekstrak n-heksa
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Meegada, Purna Prasad, Rama Mohan Pathapati, Sriharsha Rayam, and Raveendra Kumar Nallabothula. "Evaluation of analgesic and anti-inflammatory properties of the Allium cepa extract in rats." International Journal of Basic & Clinical Pharmacology 10, no. 7 (2021): 789. http://dx.doi.org/10.18203/2319-2003.ijbcp20212374.

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Background: The onion plant (Allium cepa) is the most widely cultivated species of the genus Allium. It has antibiotic, antidiabetic, antihypercholesterolemic, antioxidant, hemostatic, antimutagenic effects. The current study is aimed to evaluate analgesic and anti-inflammatory properties of Allium cepa extracts in rat models.Methods: In this study analgesic activity in rats is tested by Eddy’s hot plate method, tail flick method. In Eddy’s hot plate method rats are individually placed on the heated plate of the analgesic meter maintained at 550C and mean reaction time was calculated at regula
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Kousar, Begum* Naziya Begum Shaik Reshma Wajiha Fatima Mariyanaaz Ali and Ayesha Sultana. "PTEROCARPUS MARSUPIUM EXTRACTION AND EVALUATION FOR DIABETIC NEUROPATHY." Indo American Journal of Pharmaceutical Sciences 04, no. 07 (2017): 1888–97. https://doi.org/10.5281/zenodo.826969.

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Herbal medicines are considered to offer gentle means of managing chronic diseases at a lower cost. Traditional Medicines derived from medicinal plants are used by about 60% of the world’s population. Diabetes is an important human ailment afflicting many from various walks of life in different countries. In India it is proving to be a major health problem, especially in the urban areas. Pterocarpus marsupium. (PM) heartwood and bark have been majorly used as antidiabetic remedies in many cultures for thousands of years. The aim of this research is to address the existing evidence on antidiabe
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Zhou, Quanhong, Yuhua Bao, Xin Zhang, et al. "Optimal interval for hot water immersion tail-flick test in rats." Acta Neuropsychiatrica 26, no. 4 (2013): 218–22. http://dx.doi.org/10.1017/neu.2013.57.

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BackgroundThe hot water tail-flick test is widely used to measure the degree of nociception experienced by laboratory animals. This study was carried out to optimise interval times for the hot water immersion tail-flick tests in rats.MethodTen different intervals from 10 s to 1 h were tested in 60 Sprague–Dawley male rats. At least eight rats were tested for each interval in three consecutive hot water tail-flick tests. Dixon's up-and-down method was also used to find the optimal intervals. The same rats were then divided into two groups. In Group N, naloxone was injected to reverse the prolon
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Fan, Sook-Ha, Noraisah Akbar Ali, and Dayang Fredalina Basri. "Evaluation of Analgesic Activity of the Methanol Extract from the Galls ofQuercus infectoria(Olivier) in Rats." Evidence-Based Complementary and Alternative Medicine 2014 (2014): 1–6. http://dx.doi.org/10.1155/2014/976764.

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The present study aims to investigate the analgesic activity of the methanol extract of the galls ofQuercus infectoriain rats using hot plate and tail-flick methods. The extract was administered intraperitoneally at a dose of 20 mg/kg while morphine sulfate and sodium salicylate (10 mg/kg) served as standards. The methanol extract exhibited significant analgesic activity in the tail-flick model (P<0.05) by increasing the reaction time of the rats to 8.0 sec at 30 min after treatment in comparison to control (4.4 sec). Morphine sulfate produced a reaction time of 11.9 sec in the same test. A
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Dila Keswara, Yane, and Sri Rejeki Handayani. "Uji Aktivitas Analgetik Ekstrak Etanol Daun Inggu (Ruta angustifolia [l.] Pers) Pada Tikus Putih Jantan." Journal Syifa Sciences and Clinical Research 1, no. 2 (2019): 57–69. http://dx.doi.org/10.37311/jsscr.v1i2.2662.

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Pain is an uncomfortable feeling caused by strong or destructive stimulation, if unchecked can affect daily routine. This study aims to determine the analgesic effect and dosage of the leaf extract ethanol, as well as to determine the effectiveness of the leaf extract ethanol as a narcotic analgesic by the Tail Flick method or as a non-narcotic analgesic by the Paw Pressure Test Randall Selitto method. Extraction was done by maceration of leaf powder with a solvent 96% ethanol. 25 male Wistar white rats were divided into 5 groups, positive group mefenamic acid 9 mg /200 g BW for the Paw Pressu
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Book chapters on the topic "Tail flick method"

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V, N. V. L. Suvarchala Reddy, M. Ganga Raju, N. Arkprabha, P. Manasa, and D. Pushyami Sudha. "ANTI-INFLAMMATORY AND ANALGESIC ACTIVITY OF METHANOLIC EXTRACT OF JASMINUM MULTIFLORUM LEAVES." In Futuristic Trends in Pharmacy & Nursing Volume 3 Book 18. Iterative International Publishers, Selfypage Developers Pvt Ltd, 2024. http://dx.doi.org/10.58532/v3bipn18p5ch2.

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Jasminum multiflorum, belonging to the Oleaceae family, is a significant medicinal plant used to treat a variety of illnesses. In the current investigation, an effort was made to examine the anti-inflammatory and analgesic results of methanolic extract of the Jasminum multiflorum in various animal models. Acute toxicity studies revealed that the extract was safe in doses up to 2000 mg/kg.For this study, two doses were selected:200 mg/kg and 400 mg/kg bodyweight. Utilizing carrageenan-induced paw edema in albino rats and other animal models, anti-inflammatory effectiveness was assessed, as was
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