Relevant bibliographies by topics / The N-end rule

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  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers

Academic literature on the topic 'The N-end rule'

Author: Grafiati
Published: 7 July 2024
Last updated: 31 July 2025

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Journal articles on the topic "The N-end rule"

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Varshavsky, A. "The N-end Rule." Cold Spring Harbor Symposia on Quantitative Biology 60 (January 1, 1995): 461–78. http://dx.doi.org/10.1101/sqb.1995.060.01.051.

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Varshavsky, Alexander. "The N-end rule." Cell 69, no. 5 (1992): 725–35. http://dx.doi.org/10.1016/0092-8674(92)90285-k.

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Tasaki, Takafumi, Shashikanth M. Sriram, Kyong Soo Park, and Yong Tae Kwon. "The N-End Rule Pathway." Annual Review of Biochemistry 81, no. 1 (2012): 261–89. http://dx.doi.org/10.1146/annurev-biochem-051710-093308.

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Tobias, J., T. Shrader, G. Rocap, and A. Varshavsky. "The N-end rule in bacteria." Science 254, no. 5036 (1991): 1374–77. http://dx.doi.org/10.1126/science.1962196.

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Hurtley, Stella M. "Another N-end rule to add." Science 362, no. 6418 (2018): 1014.11–1016. http://dx.doi.org/10.1126/science.362.6418.1014-k.

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Kim, Jeong-Mok, and Cheol-Sang Hwang. "Crosstalk between the Arg/N-end and Ac/N-end rule." Cell Cycle 13, no. 9 (2014): 1366–67. http://dx.doi.org/10.4161/cc.28751.

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Eldeeb, Mohamed, and Richard Fahlman. "The-N-End Rule: The Beginning Determines the End." Protein & Peptide Letters 23, no. 4 (2016): 343–48. http://dx.doi.org/10.2174/0929866523666160108115809.

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Varshavsky, Alexander. "The N-end rule at atomic resolution." Nature Structural & Molecular Biology 15, no. 12 (2008): 1238–40. http://dx.doi.org/10.1038/nsmb1208-1238.

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Wojcik, Cezary. "Dipeptides: rulers of the N-end rule." Trends in Cell Biology 10, no. 9 (2000): 367. http://dx.doi.org/10.1016/s0962-8924(00)01827-4.

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Dougan, David A., and Alexander Varshavsky. "Understanding the Pro/N-end rule pathway." Nature Chemical Biology 14, no. 5 (2018): 415–16. http://dx.doi.org/10.1038/s41589-018-0045-0.

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Dissertations / Theses on the topic "The N-end rule"

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Wang, Kevin H. Ph D. Massachusetts Institute of Technology. "Tuning strength and specificity in the N-end rule." Thesis, Massachusetts Institute of Technology, 2008. http://hdl.handle.net/1721.1/45808.

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Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Biology, 2008.<br>Title of thesis missing on title page; supplied from the abstract, p. [1].<br>Includes bibliographical references (p. 107-115).<br>Protein degradation is a central mechanism in the regulation of gene expression and activity. Proteolysis regulates not only homeostatic activities, but also the cell's responses to stress. A recurring question underlying this regulatory process is the specificity of substrate selection by the proteolytic machinery. I designed an unbiased selection to isolate N-terminal degradation s
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Stein, Benjamin J. (Benjamin Joseph). "Substrate specificity of [alpha]-proteobacterial N-end rule adaptors." Thesis, Massachusetts Institute of Technology, 2016. http://hdl.handle.net/1721.1/104102.

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Thesis: Ph. D., Massachusetts Institute of Technology, Department of Biology, 2016.<br>This electronic version was submitted by the student author. The certified thesis is available in the Institute Archives and Special Collections.<br>Cataloged from student-submitted PDF version of thesis. "June 2016." In title on title page [alpha] appears as lower case Greek letters.<br>Includes bibliographical references (pages 103-118).<br>by Benjamin J. Stein.<br>Ph. D.
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Woollard, Geoffrey Robert Paget. "Redesign of the N-end rule protein ClpS for use in high-throughput N-end protein sequencing." Thesis, University of British Columbia, 2014. http://hdl.handle.net/2429/46377.

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Current protein sequencing methods include mass spectrometry and Edman degradation. We envision a novel high-throughput protein sequencing method using affinity adapters to recognize the N-terminal residue of a denatured peptide in an iterative process. This thesis takes a first step toward designing robust and selective affinity reagents. We outline our pipeline for designing selective protein adapters that recognize the N-terminal amino acid of a peptide independent of the following sequence. We based our design on a substrate recognition protein in the N-end rule pathway, ClpS. The bacteria
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Jones, Peter Dafydd. "The function of the N-end rule pathway in Arabidopsis seed germination." Thesis, University of Nottingham, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.546566.

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Tremblay, Alexandre. "Une approche afin de produire les différentes conformations de caspase-7 tout en contrôlant l'induction de l'apoptose." Mémoire, Université de Sherbrooke, 2011. http://savoirs.usherbrooke.ca/handle/11143/4081.

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Caspase-7 is a member of a family of cysteine proteases that includes apoptotic initiators (caspases-8, -9 and -10) and executors (caspases-3, -6 and -7). During apoptosis, executioner caspases are cleaved by initiator caspases either by the extrinsic (death receptors) or by the intrinsic (mitochondrial) pathway of caspase activation. Caspase-7 is an obligate dimer in the cell and cleavage of the interdomain connector (IDC), which split the catalytic domain in two subunits, at either site 1 or site 2 allows the conversion of the enzyme from the zymogen (inactive) state to the active state thro
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Dissmeyer, Nico [Verfasser]. "Protein recognition and degradation via the N-end rule pathway : [kumulative Habilitation] / Nico Dissmeyer." Halle, 2018. http://d-nb.info/1168627575/34.

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Faden, Frederik [Verfasser]. "A simple technique for N-end rule-controlled conditional protein accumulation in vivo / Frederik Faden." Halle, 2017. http://d-nb.info/1138641855/34.

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Naumann, Christin [Verfasser]. "Identifizierung und Charakterisierung neuer Substrate des N-end rule pathways in Arabidopsis thaliana / Christin Naumann." Halle, 2017. http://d-nb.info/113349224X/34.

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Rooney, D. J. "An investigation into the mechanism and function of cysteine oxidation in the plant N-end rule pathway." Thesis, University of Nottingham, 2017. http://eprints.nottingham.ac.uk/39348/.

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Flooding events are becoming more common throughout the world as a result of climate change, resulting in reduced crop yields. It was recently discovered that plants sense low oxygen (O2) (associated with flooding) through regulated proteolysis of the group VII Ethylene Response Factor transcription factors (ERFVIIs), via the Cys-Arg/N-end rule pathway of ubiquitin mediated proteolysis, which also senses another gas, nitric oxide (NO). The N-terminal (Nt) Cys of physiological (e.g. ERFVIIs) and artificial substrates was shown to be key for N-end rule function, and work in mammalian systems sug
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Wang, Xu. "The role of ethylene and the N-end rule pathway in the regulation of Arabidopsis seed dormancy." Electronic Thesis or Diss., Sorbonne université, 2019. http://www.theses.fr/2019SORUS421.

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L'éthylène comme la stratification au froid et le GA3, stimule la germination des graines d'Arabidopsis thaliana (Col-0) ayant une dormance primaire, à 25 °C et à l'obscurité. L'élimination de la dormance au froid n'exige pas ETR1, EIN4 et EIN2, alors que l'effet du GA3 nécessite ETR1. L'effet stimulateur de l'éthylène est associé à une réduction de l'expression des gènes impliqués dans les voies de signalisation des GAs (DELLAs) et de l'ABA (ABI5). Les graines du mutant prt6 affectées dans la voie "N-end rule" de la protéolyse, sont insensibles à l'éthylène, montrant que PRT6 intervient dans
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Books on the topic "The N-end rule"

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Braddock, Brian. End Times: Is the rule of man on Earth coming to an End? Outskirts Press, Incorporated, 2009.

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Johansen, Bruce, and Adebowale Akande, eds. Nationalism: Past as Prologue. Nova Science Publishers, Inc., 2021. http://dx.doi.org/10.52305/aief3847.

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Nationalism: Past as Prologue began as a single volume being compiled by Ad Akande, a scholar from South Africa, who proposed it to me as co-author about two years ago. The original idea was to examine how the damaging roots of nationalism have been corroding political systems around the world, and creating dangerous obstacles for necessary international cooperation. Since I (Bruce E. Johansen) has written profusely about climate change (global warming, a.k.a. infrared forcing), I suggested a concerted effort in that direction. This is a worldwide existential threat that affects every living t
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Book chapters on the topic "The N-end rule"

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Varshavsky, A., C. Byrd, I. V. Davydov, et al. "The N-End Rule Pathway." In Ubiquitin and the Biology of the Cell. Springer US, 1998. http://dx.doi.org/10.1007/978-1-4899-1922-9_8.

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Varshavsky, Alexander, Andreas Bachmair, Daniel Finley, David Gonda, and Ingrid Wünning. "The N-End Rule of Selective Protein Turnover." In Ubiquitin. Springer US, 1988. http://dx.doi.org/10.1007/978-1-4899-2049-2_12.

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Naumann, Christin, Augustin C. Mot, and Nico Dissmeyer. "Generation of Artificial N-end Rule Substrate Proteins In Vivo and In Vitro." In Methods in Molecular Biology. Springer New York, 2016. http://dx.doi.org/10.1007/978-1-4939-3759-2_6.

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Varshavsky, Alexander. "N-End Rule." In Encyclopedia of Biological Chemistry. Elsevier, 2004. http://dx.doi.org/10.1016/b0-12-443710-9/00418-x.

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"N-End Rule." In Encyclopedia of Genetics, Genomics, Proteomics and Informatics. Springer Netherlands, 2008. http://dx.doi.org/10.1007/978-1-4020-6754-9_11250.

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Varshavsky, Alexander. "The Ubiquitin System and the N-End Rule Pathway." In The Ubiquitin-Proteasome Proteolytic System. WORLD SCIENTIFIC, 2002. http://dx.doi.org/10.1142/9789812776877_0002.

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Zenker, Martin. "UBR1 and the N-end Rule Pathway and the Johanson–Blizzard Syndrome." In Inborn Errors Of Development. Oxford University PressNew York, NY, 2008. http://dx.doi.org/10.1093/oso/9780195306910.003.0135.

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Abstract Johanson–Blizzard syndrome (JBS; OMIM 243800) is an autosomal recessive condition comprising multiple congenital anomalies and frequent mental retardation. Its most constant features are nasal wing hypoplasia and congenital exocrine pancreatic insufficiency, which is most likely due to intrauterine-onset destruction of acinar cells. Additional features include short stature, oligodontia, deafness, scalp defects, hypothyroidism, imperforate anus, and genitourinary malformations. JBS results from homozygous or compound heterozygous mutations at UBR1, leading to a loss of function of the
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Zenker, Martin. "UBR1, the N-End-Rule Pathway, and the Johanson-Blizzard Syndrome." In Epstein's Inborn Errors of Development. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199934522.003.0166.

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Davydov, Ilia V., John H. Kenten, Yassamin J. Safiran, et al. "In Vitro Screening for Substrates of the N‐End Rule–Dependent Ubiquitylation." In Methods in Enzymology. Elsevier, 2005. http://dx.doi.org/10.1016/s0076-6879(05)99029-0.

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Marc, Brose. "The ‘Newest Rule of Gunn’?, or: Is there a Negative Construction n sDm=f with a Present/Imperfective sDm=f Form?" In Crossroads VI: Between Egyptian Linguistics and Philology. Widmaier Verlag, 2024. http://dx.doi.org/10.37011/studmon.30.01.

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In the majority of the recent grammars of Middle Egyptian/Earlier Egyptian there is no negative construction n sDm=f containing a present/imperfective sDm=f form. This article discusses the question whether such a negative construction might be attestable — a question which can only be understood by revisiting the complicated research history. After an overview of the relevant steps of research history a list of several instances is offered where the negative construction n sDm=f with a present/imperfective sDm=f form and present/imperfective function could be assumed, and also the problems em
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Conference papers on the topic "The N-end rule"

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Zˇiha, Kalman, and Branko Blagojevic´. "Fatigue Yield of Ship Structures." In ASME 2009 28th International Conference on Ocean, Offshore and Arctic Engineering. ASMEDC, 2009. http://dx.doi.org/10.1115/omae2009-80222.

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The paper on the first place summarizes the fatigue yield approach as a cause-effect interaction between fatigue damage progression and fatigue endurance. Secondly it investigates the fatigue strength worsening on experimental S-N data and the load variability effects in shipbuilding. Next it applies the Classification Society’s rule-based procedure for fatigue analysis of ship’s structure that uses a simplified fatigue strength assessment method. The example elaborates fatigue yield effect on the seagoing operation of a double hull 47400 tdw tanker. At the end the paper recommends the procedu
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Samanta, Asokendu, and P. Kurinjivelan. "Fatigue Life Assessment of Offshore Patrol Vessel." In ASME 2009 28th International Conference on Ocean, Offshore and Arctic Engineering. ASMEDC, 2009. http://dx.doi.org/10.1115/omae2009-79005.

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Fatigue is a phenomenon, which needs to be considered in the present day’s vessel design. The welded joints are particularly affected by the fatigue damage due to high stress concentrations caused by the metallurgical discontinuities present in the weld. For oil tankers and bulk carriers adequate guidelines for the fatigue strength assessment have been established by the classification societies. But for navy vessel, like offshore patrol vessel, the design guidelines for the fatigue strength analysis are not widely available. In the present paper, an attempt has been made to calculate the fati
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Rakoczy, Przemyslaw, and Cory J. Hogan. "Service Life Evaluation of Fleet of Municipal Trains." In ASME 2012 Rail Transportation Division Fall Technical Conference. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/rtdf2012-9423.

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When a fleet of trains is nearing the end of its service life, the city transit authorities have to decide whether to replace the aging train inventory or apply life extension remediation to the existing fleet. Replacement of the entire inventory comes at a significant cost. Therefore, evaluation of the remaining service life and possible life extension methods for the current fleet is worth investigating. The objective of this study is the evaluation of remaining service life of existing municipal trains and assessment of risk associated with life extension in order to help authorities in the
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McGill, Robert O., Russell C. Cipolla, Eric J. Houston, and Ronald J. Janowiak. "Application Examples of ASME Code Case N-513 Implementation." In ASME 2019 Pressure Vessels & Piping Conference. American Society of Mechanical Engineers, 2019. http://dx.doi.org/10.1115/pvp2019-94009.

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Abstract Code Case N-513 provides evaluation rules and criteria for temporary acceptance of flaws, including through-wall flaws, in moderate energy piping. The application of the Code Case is restricted to Class 2 and 3 systems, so that safety issues regarding short-term system operation are minimized. The first version of the Code Case was published in 1997. Since then, there have been five revisions to the Code Case that have been published by ASME. The Code Case has been used numerous times by utilities to avoid unscheduled shutdowns without impacting plant safety. Recent revisions of Code
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Cuvilliez, Sam, Jia Li, Zichen Kong, Jürgen Rudolph, François Billon, and Hai Xie. "AFCEN Fatigue Calculations Benchmark: Implementation of the RCC-M Rules in Probationary Phase for Environmentally Assisted Fatigue (EAF) Assessment on a Simple Test Case." In ASME 2021 Pressure Vessels & Piping Conference. American Society of Mechanical Engineers, 2021. http://dx.doi.org/10.1115/pvp2021-61522.

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Abstract In the framework of fatigue assessment of Nuclear Power Plant (NPP) components, Environmentally Assisted Fatigue (EAF) is nowadays receiving an increased level of attention by regulatory bodies, code committees and utilities worldwide. This concerns particularly the Long Term Operation (LTO) of NPPs, where EAF may impact significantly the stress reports that are revised for Periodic Safety Reviews (PSRs), but also nuclear new builds in some cases. In this context, several guidance documents were developed and issued, the most well-known example being the NUREG/CR-6909 report [1] prepa
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McGill, Robert O., Kari L. Den Herder, Daniel B. Patten, and Steven P. Queen. "Recent Applications of ASME Code Case N-513 for Evaluation of Nonplanar Leaking Flaws." In ASME 2008 Pressure Vessels and Piping Conference. ASMEDC, 2008. http://dx.doi.org/10.1115/pvp2008-61639.

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ASME Code Case N-513, Evaluation Criteria for Temporary Acceptance of Flaws in Moderate Energy Class 2 or 3 Piping, provides evaluation rules for the temporary acceptance of flaws, including through-wall flaws, in moderate energy Class 2 or 3 piping without performing repair/replacement activities. The Code Case has gone through three revisions with the latest approved by ASME Section XI being N-513-2. The Code Case allows for evaluation of both planar and nonplanar flaws. The planar flaw evaluation uses the rules in Appendix C of ASME Section XI. The nonplanar flaw evaluation uses the procedu
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Simonova, N. N., and Ya A. Korneeva. "The Functional States’ Dynamics During the Shift Period of Oil Exploration Workers with Different Work and Rest Regimes as a Marker of Their Psychological Safety." In SPE International Health, Safety, Environment and Sustainability Conference and Exhibition. SPE, 2024. http://dx.doi.org/10.2118/220482-ms.

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The shift method of labor organization is widely used in various industries [1], one of which is the exploration and production of oil and gas. Scientific studies have covered in detail the adverse impact of the Far North and the Arctic conditions on the professional health of shift personnel, taking into account the polar stress syndrome [2-11]. At the same time, in the southern regions of the country the climate is characterized by pronounced continentality, characterized by dry and very hot summers, cold winters with strong winds and snowstorms [12]. These features certainly have an adverse
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Cimock, Dylan, Eric J. Houston, Russell C. Cipolla, and Robert O. McGill. "Technical Basis for Proposed Fifth Revision to ASME Code Case N-513." In ASME 2018 Pressure Vessels and Piping Conference. American Society of Mechanical Engineers, 2018. http://dx.doi.org/10.1115/pvp2018-84092.

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Code Case N-513 provides evaluation rules and criteria for temporary acceptance of flaws, including through-wall flaws, in moderate energy piping. The application of the Code Case is restricted to moderate energy, Class 2 and 3 systems, so that safety issues regarding short-term, degraded system operation are minimized. The first version of the Code Case was published in 1997. Since then, there have been four revisions to augment and clarify the evaluation requirements and acceptance criteria of the Code Case that have been published by ASME. The technical bases for the original version of the
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Faidy, C. "Uncertainties and Margins in Environmental Fatigue Analysis Rules." In ASME 2014 Pressure Vessels and Piping Conference. American Society of Mechanical Engineers, 2014. http://dx.doi.org/10.1115/pvp2014-28551.

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During the past 30 years the main rules for fatigue analysis of pressure vessels were based on elastic approaches in order to evaluate cyclic strain amplitude and compare with an S-N fatigue curve for the corresponding material. After review of some rules in different Nuclear and Non-Nuclear Codes, like ASME Boiler &amp; Pressure Vessel Code Section III, French RCC-M and RCC-MRx, European Standards EN 13445, the major conservatisms and uncertainties of different rules are discussed. All these Codes propose simple rules to evaluate the strain amplitude based on elastic approaches and simplified
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Faidy, Claude. "Fatigue Design Rules in Pressure Vessel Codes Uncertainties and Remaining Open Points." In 2014 22nd International Conference on Nuclear Engineering. American Society of Mechanical Engineers, 2014. http://dx.doi.org/10.1115/icone22-30715.

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During the past 30 years the main rules for fatigue analysis of pressure vessels were based on elastic approaches in order to evaluate a cyclic strain amplitude and compare with an S-N fatigue curve for the corresponding material. After review of some rules in different Nuclear and Non Nuclear Codes, like ASME Boiler &amp; Pressure Vessel Code Section III, French RCC-M and RCC-MRx, European Standards EN 13445, the major conservatisms and uncertainties of different rules are discussed. All these Codes propose simple rules to evaluate the strain amplitude based on elastic approaches and simplifi
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