Relevant bibliographies by topics / Theacrine

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  2. Dissertations / Theses

Academic literature on the topic 'Theacrine'

Author: Grafiati
Published: 9 October 2024
Last updated: 31 July 2025

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Journal articles on the topic "Theacrine"

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Yani, Tan, Lin Junming, Zhang Zhen, He Rongrong, and Li Sha. "Studies on Sustained Release Tablets of Theacrine with Erodible Matrix Material." Journal of Pharmaceutical and Biomedical Sciences 11, no. 03 (2021): 60–71. https://doi.org/10.5281/zenodo.4818212.

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<strong>Background </strong>Theacrine is a purine alkaloid with sedative, hypnotic and liver protection effects, which was investigated in treatment of insomnia, liver damage and hepatic steatosis. These are generally chronic diseases needing long-term medication. Sustained release preparations have good effect and compliance in prolonged treatment. <strong>Aim</strong> This study aimed to develop theacrine sustained release tablets using wax matrix material with simple preparing process. Methods: The content assay method of theacrine was developed using UV-visible spectrophotometry, and the m
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Chen, Xiaomin, Shuxian Shao, Ruxing Yang, et al. "Identification of Co-Expressed Genes Related to Theacrine Synthesis in Tea Flowers at Different Developmental Stages." International Journal of Molecular Sciences 22, no. 24 (2021): 13394. http://dx.doi.org/10.3390/ijms222413394.

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Jiaocheng kucha is the first reported tea germplasm resource which contains theacrine founded in Fujian Province. Currently, the anabolic mechanism of theacrine within tea leaves is clear, but there are few studies focused on its flowers. In order to further explore the mechanism of theacrine synthesis and related genes in flowers, current study applied Jiaocheng kucha flowers (JC) as test materials and Fuding Dabaicha flowers (FD) as control materials to make transcriptome sequencing, and determination of purine alkaloid content in three different developmental periods (flower bud stage, whit
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Vieira-Cavalcante, Victor, Julio Cezar Schamne, Felippi Gonçalves, et al. "Different doses of theacrine do not improve 4 km cycling time trial performance." Applied Physiology, Nutrition, and Metabolism 50 (January 1, 2025): 1–11. https://doi.org/10.1139/apnm-2024-0442.

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The aim of the present study was to test the effects of different doses of anhydrous theacrine (3 and 6 mg·kg−1 of body mass) on 4 km cycling time trial performance. Nineteen (11 men and 8 women) cyclists (30.8 ± 10.0 years, 71.7 ± 11.8 kg, 170.1 ± 9.0 cm, and 17.0 ± 6.2% of body fat) completed three 4 km cycling time trials after ingesting either placebo, or 3 or 6 mg·kg−1 of body mass of theacrine. No significant differences ( p &lt; 0.05) were observed in time to cover the 4 km cycling time trial between the placebo, 3 mg·kg−1 of theacrine, and 6 mg·kg−1 of theacrine conditions. However, th
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Yang, Maoxian, Peng Shen, Longsheng Xu, Min Kong, Congcong Yu, and Yunchao Shi. "Theacrine alleviates sepsis-induced acute kidney injury by repressing the activation of NLRP3/Caspase-1 inflammasome." PeerJ 10 (October 4, 2022): e14109. http://dx.doi.org/10.7717/peerj.14109.

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Acute kidney injury (AKI) is a frequent and serious complication of sepsis, which results in a rapid decline of kidney function. Currently, there are no curative therapies for AKI. Theacrine is a purine alkaloid and exerts significant role in regulating inflammation, oxidative stress, and mood elevation. The study aims to evaluate the biological role and potential mechanism of theacrine in septic AKI. The murine and cellular models of septic AKI were established in lipopolysaccharide (LPS)-treated C57BL/6 mice and HK-2 cells, respectively. The effect of theacrine on alleviating septic AKI was
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Jhuo, Cian-Fen, Yu-Yu Hsu, Wen-Ying Chen, and Jason T. C. Tzen. "Attenuation of Tumor Development in Mammary Carcinoma Rats by Theacrine, an Antagonist of Adenosine 2A Receptor." Molecules 26, no. 24 (2021): 7455. http://dx.doi.org/10.3390/molecules26247455.

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Caffeine has been reported to induce anti-tumor immunity for attenuating breast cancer by blocking the adenosine 2A receptor. Molecular modeling showed that theacrine, a purine alkaloid structurally similar to caffeine, might be an antagonist of the adenosine 2A receptor equivalent to or more effective than caffeine. Theacrine was further demonstrated to be an effective antagonist of the adenosine 2A receptor as its concurrent supplementation significantly reduced the elevation of AMPK phosphorylation level in MCF-7 human breast cells induced by CGS21680, an agonist of adenosine 2A receptors.
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Cerqueira, H. Santa Capita, H. Tourinho Filho, M. Corrêa, and C. E. Martinelli. "Theacrine does not enhance physical performance or training status over 8 weeks." Comparative Exercise Physiology 18, no. 2 (2022): 171–77. http://dx.doi.org/10.3920/cep210034.

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Fatigue is a condition that may affect physical performance during training sessions. Consequently, this will impact training performance and will also affect the performance of the individual in the long term. Caffeine is extensively used to counteract fatigue; however, it contains several side effects. Theacrine might be used as an alternative to caffeine, providing the same benefits without the side effects. The current study aimed to investigate the effects of 8 weeks of supplementation with theacrine on physical performance and training status of young amateur athletes. Twenty-two subject
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7

Song, Qitai, Yao Liu, and Ye Tian. "Theacrine alleviates inflammation and lung injury in septic mice by mediating SIRT3." Tropical Journal of Pharmaceutical Research 22, no. 11 (2024): 2259–64. http://dx.doi.org/10.4314/tjpr.v22i11.3.

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Purpose: To evaluate the effect of theacrine on sepsis progression and sepsis-induced lung injury and its mechanism of action.&#x0D; Methods: Lung injury model of lipopolysaccharide (LPS)-induced sepsis was made in the mice by injected with 3 mg/kg LPS dissolved in 50 μL PBS or only PBS (control group = 10). The remaining three groups (divided into ten mice per group) were administered theacrine (10, 20, and 40 mg/kg), by oral gavage 1 hour after LPS treatment. Hematoxylin and eosin (H&amp;E) staining was performed to confirm the effect of theacrine on lung injury. Quantitative polymerase chai
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Mumford, Petey W., Shelby C. Osburn, Carlton D. Fox, Joshua S. Godwin, and Michael D. Roberts. "A Theacrine-Based Supplement Increases Cellular NAD+ Levels and Affects Biomarkers Related to Sirtuin Activity in C2C12 Muscle Cells In Vitro." Nutrients 12, no. 12 (2020): 3727. http://dx.doi.org/10.3390/nu12123727.

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There is evidence in rodents to suggest that theacrine-based supplements modulate tissue sirtuin activity as well as other biological processes associated with aging. Herein, we examined if a theacrine-based supplement (termed NAD3) altered sirtuin activity in vitro while also affecting markers of mitochondrial biogenesis. The murine C2C12 myoblast cell line was used for experimentation. Following 7 days of differentiation, myotubes were treated with 0.45 mg/mL of NAD3 (containing ~2 mM theacrine) for 3 and 24 h (n = 6 treatment wells per time point). Relative to control (CTL)-treated cells, N
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Roberts, Michael D., Shelby C. Osburn, Joshua S. Godwin, et al. "Enhance Trial: Effects of NAD3® on Hallmarks of Aging and Clinical Endpoints of Health in Middle Aged Adults: A Subset Analysis Focused on Blood Cell NAD+ Concentrations and Lipid Metabolism." Physiologia 2, no. 1 (2022): 20–31. http://dx.doi.org/10.3390/physiologia2010002.

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Limited pre-clinical and clinical data suggest theacrine or theacrine-based supplements modulate biological processes associated with lipid metabolism and aging. Herein, we sought to examine if 12 weeks of daily supplementation with a theacrine-based supplement (termed NAD3®; 312 mg of combined Wasabia japonica freeze-dried rhizome standardized for isothicyantes, theacrine, and copper (I)niacin chelate) altered serum lipids as well as select nicotinamide adenine dinucleotide (NAD+)-associated metabolites in peripheral blood mononuclear cells (PBMCs). Twenty-eight participants (12 males, 16 fem
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Cerqueira, Henrique Santa Capita, Hugo Tourinho Filho, Marcos Corrêa Junior, and Carlos Eduardo Martinelli Junior. "Effects of Theacrine as a Pre-Workout Supplement." International Journal of Environmental Research and Public Health 19, no. 21 (2022): 14037. http://dx.doi.org/10.3390/ijerph192114037.

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The search to increase physical performance is inherent to physical activity practitioners, and nutrition features are among the alternatives to seeking such an increase. The literature from the area has shown that different substances can promote beneficial effects over physical performance. One substance that has come into the spotlight is theacrine, an alkaloid similar to caffeine, which aims to increase physical performance. However, the studies on this supplement are scarce. Therefore, this study is a randomized, controlled trial that aimed to verify the effects of theacrine supplementati
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Dissertations / Theses on the topic "Theacrine"

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Gardiner, C. "Investigating the effects of psychoactive substances on subsequent sleep." Phd thesis, Australian Catholic University, 2024. https://acuresearchbank.acu.edu.au/download/62d91f7dd7190320e919b54c999ec98a8252577b6f77e995b89a96f68efef3e9/4381487/Gardiner_2024_Investigating_the_effects_of_psychoactive_substances.pdf.

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Sleep is essential for health and wellbeing. However, it is estimated that up to 40% of the population fail to attain the recommended seven to nine hours of sleep per night. A key contributor to these high rates of sleep insufficiency is the consumption of psychoactive substances. Two widely accessible psychoactive substances are alcohol and caffeine. Alcohol, the most commonly consumed hypnotic, is consumed by approximately 40% of the population, while caffeine, the most commonly consumed stimulant, is consumed by approximately 80% of the population. This thesis aims to investigate the impact
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