Relevant bibliographies by topics / These compounds showed mild to moderate antibacterial activity against Gram positive as well as Gram negative bacteria

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Academic literature on the topic 'These compounds showed mild to moderate antibacterial activity against Gram positive as well as Gram negative bacteria'

Author: Grafiati
Published: 2 June 2025
Last updated: 31 July 2025

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Journal articles on the topic "These compounds showed mild to moderate antibacterial activity against Gram positive as well as Gram negative bacteria"

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Mohd., Imran*. "ANTIMICROBIAL ACTIVITY EVALUATION OF SOME (Z)-2- (2-OXO-1-((ARYLAMINO)METHYL)INDOLIN-3-YLIDENE)-N- (4-(2-OXO-2H-CHROMEN-3-YL)THIAZOL-2-YL)HYDRAZINE- 1-CARBOXAMIDES." Indo American Journal of Pharmaceutical Sciences (IAJPS) 03, no. 09 (2016): 988–895. https://doi.org/10.5281/zenodo.154116.

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Fourteen(Z)-2-(2-oxo-1-((arylamino)methyl)indolin-3-ylidene)-N-(4-(2-oxo-2H-chromen-3-yl)thiazol-2 yl)hydrazine-1-carboxamides 4a-4n were prepared by treating (Z)-N-(4-(2-oxo-2H-chromen-3-yl)thiazol-2-yl)-2-(2- oxoindolin-3-ylidene)hydrazine-1-carboxamide 3 with the aryl amines and formaldehyde. The chemical structures of these compounds were elucidated by their physical constants, spectral data and elemental analysis. These compounds were investigated for their antimicrobial activity against five Gram-positive bacteria, namely, S. aureus, E. faecalis, S. epidermidis, B. subtilis and B. cereus
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Gosavi, Seema A., Dattatray H. Nandal, and Sarita S. Pawar. "Synthesis and Biological Evaluation of Some Novel Mannich Bases of Isoxazoline Derivatives as Possible Antimicrobial Agents." Asian Journal of Chemistry 31, no. 12 (2019): 2821–26. http://dx.doi.org/10.14233/ajchem.2019.22247.

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Novel isoxazoline derivatives were synthesized by condensation of substituted acetophenones with aldehyde in presence of alcoholic NaOH to get intermediate chalcones, which were further treated with hydroxylamine hydrochloride in presence of sodium hydroxide to get isoxazoline derivatives. The latter were refluxed separately with isonicotinic acid hydrazide and sulphanilamide in presence of formaldehyde for 6-10 h to afford corresponding Mannich bases. The structures of synthesized compounds were established on the basis of melting point, TLC, IR, 1H NMR and HRMS. Antimycobacterial activity of
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Richa, Kothari. "Synthesis of Nickel (II) Schiff Base Molecular Adducts: Spectroscopic Characterization & Antioxidant activity." American Journal of PharmTech Research 12, no. 06 (2022): 124–41. https://doi.org/10.5281/zenodo.7479291.

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ABSTRACT Transition metal complexes of Ni (II) with schiff base ligand (HL) derived from condensation of 3-Bromo benzaldehyde and hydrazine monohydrate were successfully synthesized , characterized and isolated .The schiff base ligand and its Ni(II) complexes prepared were characterized by melting  point /decomposition temperature, solubility, conductivity/ Molar conductance, UV- visible, FT-IR, XRD, TGA and elemental analysis results. In the UV-Vis study, a bathochromic shift of approximately 60 nm indicating the formation of coordinated Ni(II) complexes by more than one coordinating sit
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Mustafa M. AL-Hakiem, Rita S. Elias, and Munther A. Mohammed-Ali. "Synthesis, characterization and antibacterial evaluation of some sulfonamide Schiff base derivatives." International Journal of Research in Pharmaceutical Sciences 10, no. 4 (2019): 3535–43. http://dx.doi.org/10.26452/ijrps.v10i4.1729.

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New series of Schiff base compounds obtained from sulfa drugs have been synthesized by the reaction of sulfonamide compounds (sulfadiazine, sulfapyridine, sulfamethazine, or sulfamerazine) with corresponding aromatic aldehydes (3-pyridinecarboxaldehyde or 4-pyridinecarboxaldehyde). The synthesized compounds were characterized by FT-IR, ESI-Mass, and 1H-NMR spectroscopy to confirm the chemical structures of synthesized compounds. The purity of all synthesized compounds were verified using pre-coated TLC (MERCK) plates using dichloromethane: methanol (9:1) solvent system. The chromatographic pla
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Ranjbar-Karimi, Reza, and Alireza Poorfreidoni. "Incorporation of Fluorinated Pyridine in the Side Chain of 4-Aminoquinolines: Synthesis, Characterization and Antibacterial Activity." Drug Research 68, no. 01 (2017): 17–22. http://dx.doi.org/10.1055/s-0043-116674.

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AbstractA series of hybrid of 4-aminoquinoline and fluorinated pyridine derivatives were synthesized and their chemical structure were confirmed by 19F-NMR, 1H-NMR, 13C-NMR and FT-IR. All compounds were tested against one Gram-positive and one Gram-negative bacteria to assess their in vitro antibacterial activity. Compounds 10a, 10b, 11a and 12b showed moderate antibacterial activity against Gram-positive bacterium, Staphylococcus aureus.
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Abdillah, Latifah Ningrum, Dwi Suryanto, Kiki Nurtjahja, and Jendri Mamangkey. "Preliminary Study on Potential Bacterial Species Introducing Antibacterial Agent from Sponge in Unggeh Island Central Tapanuli, Indonesia." Jurnal Penelitian Pendidikan IPA 10, no. 7 (2024): 3780–86. http://dx.doi.org/10.29303/jppipa.v10i7.8264.

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Sponges have the potential to symbiont with bacteria that produce antibacterial compounds. This study was conducted to isolate and test the antibacterial activity of sponge symbiont bacteria. Bacterial isolates obtained were tested for antibacterial activity against Staphylococcus aureus, Bacillus subtilis and Escherichia coli using the Kirby-Bauer method. The identification results of both sponges have similarities with Clathria sp. and Hyrtios sp. symbiont bacteria obtained from both sponges as many as 16 isolates. Antibacterial activity testing had a weak inhibitory effect on isolates Sp1A,
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Vergoz, Delphine, Flore Nilly, Florie Desriac, et al. "6-Polyaminosteroid Squalamine Analogues Display Antibacterial Activity against Resistant Pathogens." International Journal of Molecular Sciences 24, no. 10 (2023): 8568. http://dx.doi.org/10.3390/ijms24108568.

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A series of 6-polyaminosteroid analogues of squalamine were synthesized with moderate to good yields and evaluated for their in vitro antimicrobial properties against both susceptible and resistant Gram-positive (vancomycin-resistant Enterococcus faecium and methicillin-resistant Staphylococcus aureus) and Gram-negative (carbapenem-resistant Acinetobacter baumannii and Pseudomonas aeruginosa) bacterial strains. Minimum inhibitory concentrations against Gram-positive bacteria ranged from 4 to 16 µg/mL for the most effective compounds, 4k and 4n, and showed an additive or synergistic effect with
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KOONA, Saradhajyothi, and Subbarao BUDIDA. "Antibacterial Potential of the Extracts of the Leaves of Azadirachta indica Linn." Notulae Scientia Biologicae 3, no. 1 (2011): 65–69. http://dx.doi.org/10.15835/nsb315470.

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Azadirachta indica A. Juss (syn. Melia azadirachta) is well known in India and popularly known as Indian neem. To evaluate antibacterial potential, the agar well diffusion assay was used against Gram-negative and Gram-positive bacteria. Penicillin and Dimethyl sulfoxide were used as positive and negative controls, respectively. Methanol extract showed the highest and chloroform extract showed moderate to good antibacterial activity. Proteus vulgaris and Micrococcus luteus were the most susceptible bacteria while Bacillus subtilis was more resistant bacterium to the hexane, chloroform and metha
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Qu, Tengfei, Lailiang Qu, Xiaoguang Wang, et al. "Design, synthesis, and antibacterial activity of novel 8-methoxyquinoline-2-carboxamide compounds containing 1,3,4-thiadiazole moiety." Zeitschrift für Naturforschung C 73, no. 3-4 (2018): 117–22. http://dx.doi.org/10.1515/znc-2017-0063.

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AbstractA series of novel 8-methoxyquinoline-2-carboxamide compounds containing 1,3,4-thiadiazole moiety was designed and synthesized by using an active substructure combination method. Then, the antibacterial activities of all the target compounds were evaluated in vitro against three Gram-positive bacteria and three Gram-negative bacteria. The antibacterial assay showed that some target compounds displayed moderate to good antibacterial efficacy in comparison with the reference drug Chloromycin. Some interesting results of structure-activity relationships were also discussed.
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Abd Alhameed, Rakia, Zainab Almarhoon, Sarah I. Bukhari, Ayman El-Faham, Beatriz G. de la Torre, and Fernando Albericio. "Synthesis and Antimicrobial Activity of a New Series of Thiazolidine-2,4-diones Carboxamide and Amino Acid Derivatives." Molecules 25, no. 1 (2019): 105. http://dx.doi.org/10.3390/molecules25010105.

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Novel thiazolidine-2,4-dione carboxamide and amino acid derivatives were synthesized in excellent yield using OxymaPure/N,N′-diisopropylcarbodimide coupling methodology and were characterized by chromatographic and spectrometric methods, and elemental analysis. The antimicrobial and antifungal activity of these derivatives was evaluated against two Gram-positive bacteria (Staphylococcus aureus and Bacillus subtilis), two-Gram negative bacteria (Escherichia coli and Pseudomonas aeruginosa), and one fungal isolate (Candida albicans). Interestingly, several samples demonstrated weak to moderate a
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Conference papers on the topic "These compounds showed mild to moderate antibacterial activity against Gram positive as well as Gram negative bacteria"

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Happitiya, H. A. D. N. N., C. M. Nanayakkara, K. G. S. U. Ariyawansa, et al. "Antibacterial Activities of Lichen-associated Fungi in Mangrove Ecosystems in Sri Lanka as Potent Candidates for Novel Antibiotic Agents." In SLIIT International Conference on Advancements in Sciences and Humanities 2023. Faculty of Humanities and Sciences, SLIIT, 2023. http://dx.doi.org/10.54389/slzp7371.

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Antimicrobial resistance is a global threat to humans, prompting an increasing interest in exploring and developing novel antimicrobial substances derived from diverse sources. Together with the emergence of new diseases the search for novel drug leads has intensified. Less explored microbial habitats have become prime targets in mining for novel antimicrobial molecules. Secondary metabolites synthesized by lichen-associated fungi are good potential targets in this regard. Hence, this study was carried out to explore the antibacterial potential of lichen associated fungi in mangrove ecosystems
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