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Journal articles on the topic 'Thrombotic complications'

Author: Grafiati

Published: 15 June 2024

Last updated: 31 July 2025

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1

Lim, Sunghee, Ji Yoon Lee, Seok Jin Kim, and Won Seog Kim. "The International Prognostic Index Is a Better Predictor of Thrombotic Complications Than the Khorana Score for Patients with Diffuse Large B-Cell Lymphoma Treated with R-CHOP: Results of a Single Center Prospective Cohort Study." Blood 120, no. 21 (2012): 5095. http://dx.doi.org/10.1182/blood.v120.21.5095.5095.

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Abstract Abstract 5095 Background Thrombotic complication is a major life threatening condition in lymphoma patients because chemotherapy as well as lymphoma cell itself can result in thrombosis. Although high rates of thrombotic complication have been reported in patients with lymphoma, the majority of data were from retrospective studies with heterogeneous group of patients. Furthermore, the frequency of thrombotic complications varied depending o the nature of studies and subtypes of lymphoma included. Thus, it is still not determined about the risk factors for thrombotic complications in l

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Makatsaria, Alexander Davidovich, Svetlana Vladimirovna Akinshina, Viktoriya Omarovna Bitsadze, and Margarita Darchievna Andreeva. "Severe obstetric complications as a manifestation of thrombotic microangiopathy." Journal of obstetrics and women's diseases 64, no. 5 (2015): 6–15. http://dx.doi.org/10.17816/jowd6456-15.

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Thrombotic microangiopathy is one of the most serious thrombotic complications characterized by microvascular thrombosis in various organs and accompanied by thrombocytopenia and hemolytic anemia. The term thrombotic microangiopathy has incorporated several nosology, which are characterized by different mechanisms of microvascular thrombosis. Currently thrombotic microangiopathy include thrombotic thrombocytopenic purpura (TTP), hemolytic uremic syndrome (HUS), heparin-induced thrombocytopenia, HELLP-syndrome. Pregnancy presents one of the key triggers to the development of thrombotic microang

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Ogurkova, O. N., M. A. Dragunova, T. E. Suslova, Yu G. Lugacheva, and R. E. Batalov. "Evaluation of the CD40 receptor-ligand system in the patients with atrial fibrillation of non-valvular genesis." Medical Immunology (Russia) 24, no. 6 (2022): 1255–64. http://dx.doi.org/10.15789/1563-0625-eot-2532.

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Thromboembolic syndrome is the most dangerous complication of atrial fibrillation which develops in about 8-15% of cases, thus presuming the role of persisting left-heart thrombosis in presence of anticoagulant therapy in some patients. When activated, the blood platelets express multiple copies of CD40L on their membrane. Hence, the soluble form of CD40 ligand is considered a marker of platelet activation and pathogenic processes associated with increased activity of the thrombotic system. Our aim was to study the content of CD40, soluble CD40 ligand and thrombomodulin in the patients with at

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4

Bitsadze, V. O., J. Kh Khizroeva, E. Grandone, et al. "Venous and arterial thromboses in ART programs: epidemiology and preventive strategies." Obstetrics, Gynecology and Reproduction 19, no. 3 (2025): 377–88. https://doi.org/10.17749/2313-7347/ob.gyn.rep.2025.656.

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Here, we review the current data on the relationship between in vitro fertilization (IVF) procedures and thrombotic complications by focusing on epidemiological, pathophysiological and clinical aspects. Although being a rare IVF complication (incidence is about 0.2 %), thrombosis poses a serious threat especially in patients with ovarian hyperstimulation syndrome (OHSS). The risk of thrombotic complications in OHSS is elevated markedly thereby underscoring the need for careful monitoring and prevention. Despite that arterial thrombosis is less common than venous thrombosis, it is more often as

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Jenner, William J., Rahim Kanji, Saeed Mirsadraee, et al. "Thrombotic complications in 2928 patients with COVID-19 treated in intensive care: a systematic review." Journal of Thrombosis and Thrombolysis 51, no. 3 (2021): 595–607. http://dx.doi.org/10.1007/s11239-021-02394-7.

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AbstractA prothrombotic state is reported with severe COVID-19 infection, which can manifest in venous and arterial thrombotic events. Coagulopathy is reflective of more severe disease and anticoagulant thromboprophylaxis is recommended in hospitalized patients. However, the prevalence of thrombosis on the intensive care unit (ICU) remains unclear, including whether this is sufficiently addressed by conventional anticoagulant thromboprophylaxis. We aimed to identify the rate of thrombotic complications in ICU-treated patients with COVID-19, to inform recommendations for diagnosis and managemen

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6

Haman, Luděk, Petr Pařízek, Radovan Malý, Jiří Duda, and Jaroslav Malý. "Analysis of Thrombotic Complications After Catheter Ablation." Acta Medica (Hradec Kralove, Czech Republic) 49, no. 1 (2006): 47–50. http://dx.doi.org/10.14712/18059694.2017.109.

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Introduction: Thromboembolic complications are described in about 1% of the patients undergoing radiofrequency catheter ablation (RFA). The aim of this study was to analyze thrombotic complications after RFA and to determine prothrombotic states in patients with thrombotic complications. Methods: We analyzed data from 400 patients (212 females) who underwent 453 RFA procedures for supraventricular tachycardias. Transthoracic echocardiography was performed one day before and after RFA in all patients. We evaluated the clinical and laboratory (in patients with thrombotic complications after RFA)

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7

Sousa Nanji, Liliana, André Torres Cardoso, João Costa, and António Vaz-Carneiro. "Analysis of the Cochrane Review: Thrombolysis for Acute Deep Vein Thrombosis. Cochrane Database Syst Rev. 2014,1: CD002783." Acta Médica Portuguesa 28, no. 1 (2015): 12. http://dx.doi.org/10.20344/amp.6286.

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<p>The standard treatment for acute deep vein thrombosis (DVT) targets to reduce immediate complications, however thrombolysis could reduce the long-term complications of post-thrombotic syndrome in the affected limb. This systematic review aimed to assess the effects of thrombolytic therapy and anticoagulation <em>versus </em>anticoagulation in people with deep vein thrombosis of the lower limb through the effects on pulmonary embolism, recurrent deep vein thrombosis, major bleeding, post-thrombotic complications, venous patency and venous function. The Cochrane Peripheral V

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Solipuram, Divya, Kathan Mehta, and Sudeep Kumar Siddappa Malleshappa. "Trends in the thrombotic complications of myeloproliferative neoplasms: A nationwide analysis." Journal of Clinical Oncology 42, no. 16_suppl (2024): 6581. http://dx.doi.org/10.1200/jco.2024.42.16_suppl.6581.

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6581 Background: Thrombotic complications are a well known cause of morbidity and mortality in Philadelphia-negative Myeloproliferative Neoplasms[Polycythemia Vera, Essential thrombocythemia, Primary Myelofibrosis]. Current study evaluated thrombotic events incidence and outcome trends in Myeloproliferative Neoplasms[MPN] from 2012 to 2020. Methods: This is a longitudinal study of thrombotic events in MPN using the Nationwide Inpatient Sample. All patients with a diagnosis of MPN admitted with any thrombotic event including arterial or venous thrombosis were included in the study. Arterial thr

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9

James, K. V., J. M. Lohr, R. M. Deshmukh, and J. J. Cranley. "Venous Thrombotic Complications of Pregnancy." Cardiovascular Surgery 4, no. 6 (1996): 777–82. http://dx.doi.org/10.1177/096721099600400618.

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A total of 30 040 pregnancies were reviewed at one institution over 5 years to determine the incidence of venous thrombotic complications. Thirty-one patients experienced such complications related to pregnancy (incidence 0.1%); 13 had deep venous thrombosis and 14 had superficial venous thrombophlebitis diagnosed by duplex ultrasound. Four had pelvic vein thrombophlebitis diagnosed by computed tomography scan; three patients (one from each group) sustained a non-fatal pulmonary embolus. Of those with deep venous thrombosis, 10 (77%) were left-sided, and three (23%) were right-sided. Three had

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Capecchi, Marco, Alessandro Ciavarella, Andrea Artoni, Maria Abbattista, and Ida Martinelli. "Thrombotic Complications in Patients with Immune-Mediated Hemolysis." Journal of Clinical Medicine 10, no. 8 (2021): 1764. http://dx.doi.org/10.3390/jcm10081764.

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Autoimmune hemolytic anemias are rare and heterogeneous disorders characterized by hemolysis, which is a well-recognized risk factor for thrombosis. The most common immune-mediated anemias are represented by autoimmune hemolytic anemia and paroxysmal nocturnal hemoglobinuria, both associated with a high rate of thrombosis. Multiple pathophysiological mechanisms for thrombosis have been proposed, involving hemolysis itself and additional effects of the immune system. Despite the increasing awareness of the thrombotic risk in these conditions, evidence-based guidance on prevention and management

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11

McFadyen, James D., Hannah Stevens, and Karlheinz Peter. "The Emerging Threat of (Micro)Thrombosis in COVID-19 and Its Therapeutic Implications." Circulation Research 127, no. 4 (2020): 571–87. http://dx.doi.org/10.1161/circresaha.120.317447.

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The recent emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the ensuing global pandemic has presented a health emergency of unprecedented magnitude. Recent clinical data has highlighted that coronavirus disease 2019 (COVID-19) is associated with a significant risk of thrombotic complications ranging from microvascular thrombosis, venous thromboembolic disease, and stroke. Importantly, thrombotic complications are markers of severe COVID-19 and are associated with multiorgan failure and increased mortality. The evidence to date supports the concept that the thrombot

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12

Routledge, David JM, Joanna Tomlins, Adrian Bloor, et al. "Incidence of Thrombotic Complications with Use of Peg-Asparginase in Treatment for Acute Lymphoblastic Leukemia (ALL) in Adults and Young Adolescent Patients." Blood 126, no. 23 (2015): 4864. http://dx.doi.org/10.1182/blood.v126.23.4864.4864.

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Abstract Introduction: Peg-Asparginase is routinely used in the chemotherapy regimens used for treatment of ALL. Incidence of thrombotic complications is well established in children but there is limited data in adult and young adolescent patients. This is retrospective analysis to assess the risk of thrombotic complications with use of Peg-Asparginase. Methods and Results: 100 patients with Acute Lymphoblastic Leukaemia treated between 2007-2015 who received Peg-Asparginase containing chemotherapy regimen were evaluated for development of thrombotic complications and pancreatitis. There were

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13

Lim, Cheryl XQ, Chuen Wen Tan, Bingwen Eugene Fan, et al. "Thrombotic Complications in COVID-19 Patients: Low Incidence of Thrombotic Complications Among Critically Ill COVID-19 Patients in Singapore." Blood 136, Supplement 1 (2020): 37–38. http://dx.doi.org/10.1182/blood-2020-138610.

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Objective Arterial and venous thrombosis are reported to be common in critically ill COVID-19 patients. This study aims to describe the thrombotic and bleeding rates in COVID-19 patients admitted to intensive care units (ICU) in Singapore. Design Retrospective observational study involving all consecutive adult COVID-19 patients who required ICU admission between 23 January 2020 and 30 April 2020. Setting National multicenter study involving all eight public hospitals in Singapore. Patients 111 consecutive COVID-19 patients who required ICU admission were included. Measurements and Main Result

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14

Babkina, Anastasiya S., Mikhail V. Pisarev, Andrey V. Grechko, and Arkady M. Golubev. "Arterial Thrombosis in Acute Respiratory Infections: An Underestimated but Clinically Relevant Problem." Journal of Clinical Medicine 13, no. 19 (2024): 6007. http://dx.doi.org/10.3390/jcm13196007.

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During the COVID-19 pandemic, there was increased interest in the issue of thrombotic complications of acute respiratory infections. Clinical reports and pathological studies have revealed that thrombus formation in COVID-19 may involve the venous and arterial vasculature. As thrombotic complications of infectious respiratory diseases are increasingly considered in the context of COVID-19, the fact that thrombosis in lung diseases of viral and bacterial etiology was described long before the pandemic is overlooked. Pre-pandemic studies show that bacterial and viral respiratory infections are a

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15

Borota, A. V., A. A. Borota, and E. V. Onishchenko. "Thrombotic Complications in Inflammatory Bowel Disease." Russian Journal of Gastroenterology, Hepatology, Coloproctology 29, no. 2 (2019): 23–26. http://dx.doi.org/10.22416/1382-4376-2019-29-2-23-26.

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The risk of thrombotic complications is known to be 3 times higher in patients with inflammatory bowel disease (IBD) than in healthy individuals, with the relative risk being 15 times higher during the periods of relapses. Aim. To study and generalize literature data available on the prevention and treatment of IBD thrombotic complications.Key findings. In the сonditions under study, the presence of chronic inflammation and increased bleeding of the intestinal wall is shown to activate the coagulation system, impair the fibrinolysis system and reduce the activity of natural anticoagulation mec

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16

Borst, Alexandra J., Debra L. Sudan, Laura A. Wang, Michael J. Neuss, Tracy G. Spears, and Thomas L. Ortel. "Bleeding and Thrombotic Complications of Pediatric Liver Transplant." Blood 128, no. 22 (2016): 1005. http://dx.doi.org/10.1182/blood.v128.22.1005.1005.

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Abstract Background: Due to underlying liver disease and the transplant process itself, pediatric abdominal transplant patients are at significant risk for bleeding and thrombotic complications. Hemostasis in these patients is nuanced, reflecting a balance of pro- and anti-coagulant factors not accurately captured by routine coagulation lab testing. Previous studies of pediatric liver transplant estimate thrombotic complications in up to 19% of patients and bleeding in 5-9%. These hematologic complications increase risk for graft failure, re-transplantation, or death. Methods: We retrospective

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17

Franchini, Massimo. "Thrombotic complications in patients with hereditary bleeding disorders." Thrombosis and Haemostasis 92, no. 08 (2004): 298–304. http://dx.doi.org/10.1160/th04-03-0148.

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SummaryThromboses in patients with hereditary bleeding disorders are uncommon. However, in some cases, the co-existence of prothrombotic risk factors may increase the likelihood of developing thrombotic complications in such patients. This review summarizes the cases of thrombosis reported in the literature and analyzes the most important risk factors for thrombosis in patients with a congenital bleeding tendency. In particular we focus on central venous catheter (CVC)-associated thrombosis, on the thrombotic complications of coagulation factor concentrate therapy and on the presence of prothr

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18

Chebotareva, N. V., A. S. Berns, M. V. Lebedeva, and S. V. Moiseev. "Clinical impact of plasma haemostasis disorders and their correction in chronic glomerulonephritis with nephrotic syndrome." Russian journal of hematology and transfusiology 65, no. 4 (2020): 473–82. http://dx.doi.org/10.35754/0234-5730-2020-65-4-473-482.

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Introduction. Thrombosis and thromboembolism are frequent complications in chronic glomerulonephritis (CGN) with nephrotic syndrome (NS), despite the use of anticoagulant therapy. Therefore, the questions of thrombosis risk assessment and thrombotic complication prevention in NS are still relevant.Aim. Description of the frequency and localisation of thromboembolic complications in CGN-NS patients and a review of approaches to their risk assessment and prevention.Main ﬁndings. The main risk predictors of venous thrombosis in NS are considered, including low serum albumin, high plasma D-dimer,

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Mancini, Mariangela, Gianmarco Randazzo, Gregory Piazza, and Fabrizio Dal Moro. "Arterial Thrombotic Complications in COVID-19: A Case of Renal Infarction." Biomedicines 10, no. 10 (2022): 2354. http://dx.doi.org/10.3390/biomedicines10102354.

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COVID-19 infection has been associated with thrombotic complications, especially venous thromboembolism. Although arterial thrombotic complications are rarely seen in these patients, we report the case of a 43-year-old patient who developed thrombosis of the main branch of the left renal artery, causing partial infarction of the left kidney associated with severe pain. He had no risk factors for thrombosis except for COVID-19 infection. We excluded any possible condition usually associated with renal artery thrombosis/embolism (i.e., cardiovascular, oncological, hematological, or rheumatic). T

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Fábrega, Emilio, Fernando Casafont, Jesús Merino, et al. "Value of plasma P‐selectin for vascular complications in liver transplantation." Clinical Transplantation 10, no. 3 (1996): 261–65. http://dx.doi.org/10.1111/j.1399-0012.1996.tb00439.x.

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Recent data suggest that plasma P‐selectin, an adhesion molecule, may be a clinically useful marker for thrombosis. Hepatic vessel thrombosis is one of the most serious complications following liver transplantation. To assess the contribution of the soluble P‐selectin to this complication, we measured plasma P‐selectin levels in 32 orthotopic liver transplantations, pre‐, intra‐, and post‐operatively. We found that levels of circulating P‐selectin were not different between cirrhotic patients and healthy subjects. Of the 32 patients, 8 had vascular complications. We found a significant increas

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Cavezzi, A., and K. Parsi. "Complications of Foam Sclerotherapy." Phlebology: The Journal of Venous Disease 27, no. 1_suppl (2012): 46–51. http://dx.doi.org/10.1258/phleb.2012.012s09.

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Foam sclerotherapy may result in drug and/or gas-related complications of a generalized or localized nature. Significant complications include anaphylactic/anaphylactoid reactions (very rare), deep vein thrombosis (1–3%), stroke (0.01%), superficial venous thrombosis (4.4%), tissue necrosis (variable frequency), oedema (0.5%) and nerve damage (0.2%). Cosmetic complications include telangiectatic matting (15–24%) and pigmentation (10–30%). Patent foramen ovale and other cardiopulmonary right-to-left shunts seem to play a role in the systemic gas-related complications. In conclusion, foam sclero

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De Wet, Charl J., and Ronald G. Pearl. "POSTOPERATIVE THROMBOTIC COMPLICATIONS." Anesthesiology Clinics of North America 17, no. 4 (1999): 895–922. http://dx.doi.org/10.1016/s0889-8537(05)70139-5.

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Broucek, Joseph R., Amanda B. Francescatti, Garth R. Swanson, Ali Keshavarzian, Marc I. Brand, and Theodore J. Saclarides. "Unusual Thrombotic Complications." American Surgeon 78, no. 6 (2012): 728–29. http://dx.doi.org/10.1177/000313481207800631.

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Peres, E. M., M. Abidi, R. Ibrahim, and S. Mellon-Reppen. "213: Thrombotic complications." Biology of Blood and Marrow Transplantation 13, no. 2 (2007): 78. http://dx.doi.org/10.1016/j.bbmt.2006.12.217.

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Ghinea, Mihaela Maria, Zizi Niculescu, C. Niculescu, and M. Grigorian. "Essential thrombocythemia – Incidence of thrombotic complications." ARS Medica Tomitana 22, no. 2 (2016): 108–12. http://dx.doi.org/10.1515/arsm-2016-0019.

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Abstract Essential thrombocytemia is a classic negative chronic myeloproliferative disease BCR-ABL characterized by global myeloid proliferation but mainly on the megacariocitary series. Most symptomatic patients show manifestations due to the vascular thromboses or haemorrhages. The objective of the paper is to evaluate the incidence of thrombotic complications. The study was carried out in the Haematology Compartment of Constanta County Clinical Hospital on a lot of 60 cases with essential thrombocytemia. The diagnosis criteria were OMS 2008 criteria. On the studied lot, on the diagnosis, 45

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Han, Yue, Wu Depei, Luping Hu, et al. "Risk Factors and Clinical Outcome of Thrombotic and Bleeding Complications in 527 Patients Following Hematopoietic Stem-Cell Transplantation (HSCT)." Blood 118, no. 21 (2011): 3076. http://dx.doi.org/10.1182/blood.v118.21.3076.3076.

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Abstract Abstract 3076 Background: Hemostatic disorders are common and potentially fatal complications in patients undergoing hematopoietic stem-cell transplantation (HSCT). Limited data exist on early diagnosis and prevention of these complications. In this study, we retrospectively investigated the outcome and risk factors associated with thrombotic and bleeding complications in HSCT recipients. Methods: From April 2004 to December 2010, 527 hematologic patients receiving HSCT (126 Auto-HSCT and 401 Allo-HSCT) were enrolled in the study, and their clinical manifestation and laboratory parame

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White, Michael H., Kavita Patel, Lazaros Kochilas, and Robert F. Sidonio. "2205 Thrombotic complications in single ventricle reconstructions for single ventricle physiology congenital heart disease." Journal of Clinical and Translational Science 2, S1 (2018): 88–89. http://dx.doi.org/10.1017/cts.2018.307.

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OBJECTIVES/SPECIFIC AIMS: Infants with single ventricle congenital heart disease (CHD) who undergo staged surgical reconstruction are among the pediatric patients at highest risk for thrombotic complications. Despite improvements in survival due to medical and surgical advancements, thrombotic complications are common and lead to increased morbidity and mortality, especially during the first two stages of surgical reconstruction. The burden of disease caused by thrombosis is not fully known, and the risk factors associated with thrombosis are not clear. Due to this knowledge gap, prevention of

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Babkina, Anastasiya S., Mikhail Y. Yadgarov, Alexey V. Volkov, Artem N. Kuzovlev, Andrey V. Grechko, and Arkady M. Golubev. "Spectrum of Thrombotic Complications in Fatal Cases of COVID-19: Focus on Pulmonary Artery Thrombosis In Situ." Viruses 15, no. 8 (2023): 1681. http://dx.doi.org/10.3390/v15081681.

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COVID-19-related thrombosis affects the venous and arterial systems. Data from 156 autopsies of COVID-19 patients were retrospectively analyzed to investigate the pattern of thrombotic complications and factors associated with pulmonary artery thrombosis and thromboembolism. Thrombotic complications were observed in a significant proportion (n = 68, 44%), with pulmonary artery thrombosis the most frequently identified thrombotic event (42, 27%). Multivariate analysis revealed that the length of hospital stay (OR 1.1, p = 0.004), neutrophil infiltration in the alveolar spaces (OR 3.6, p = 0.002

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Kumar, Vinay, Chhavi Rai, Swati Srivastava, Bhuvensh Kumar, and Iti Garg. "High altitude Provoked Thrombotic Complications." Defence Life Science Journal 5, no. 3 (2020): 224–29. http://dx.doi.org/10.14429/dlsj.5.15490.

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On rapid ascending to high-altitude particularly very high-altitude or extreme high-altitude, there is a risk of developing high-altitude illness and most people may experience acute mountain sickness which may further lead to potentially life-threatening pathologies like high-altitude pulmonary edema, high-altitude cerebral edema, high-altitude-induced thrombosis etc. if not treated on time. Hypercoagulability state associated with high-altitude which lead to the formation of a clot in the blood vessels, a condition called deep vein thrombosis, which may further complicate and lead to pulmona

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IONESCU, Vlad-Alexandru, Anca-Elena BARBU, Gina GHEORGHE, Vlad BUICA, Crista-Loredana TIUCA, and Camelia Cristina DIACONU. "Thromboembolic Complications in Patients with Digestive Malignancies." Annals of the Academy of Romanian Scientists Series of Medicine 5, no. 2 (2024): 50–64. https://doi.org/10.56082/annalsarscimed.2024.2.50.

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Introduction. Venous thromboembolism is the second leading cause of mortality in cancer patients. Patients with malignant conditions have a ninefold increased risk of thrombotic complications, and approximately 20% of patients with venous thromboembolism also associate cancer. The aim of our study was to determine the incidence and predictive factors for thromboembolic complications in patients with digestive cancers. Materials and methods: We conducted a retrospective study over six years, including 200 patients hospitalized in the Clinical Emergency Hospital of Bucharest, Romania, with diges

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Sugraliyev, A. B. "Heparin-Induced Thrombocytopenia." Kardiologiia 64, no. 5 (2024): 18–25. http://dx.doi.org/10.18087/cardio.2024.5.n2186.

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The extensive use of therapeutic doses of heparin to prevent thrombosis in critically ill patients with COVID-19 during the pandemic has led to an increased incidence of bleeding and heparin-induced thrombocytopenia (HIT). In addition, the introduction of the AstraZeneca and Johnson&Johnson vaccines against COVID-19 into clinical practice was associated with the development of a rare but very severe, adverse thrombotic complication, vaccine-induced immune thrombotic thrombocytopenia (VITT). Thrombotic complications of VITT turned out to be similar to HIT both clinically and pathophysiologi

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Nair, Velu, Ajay Sharma, Satya R. Das, D. K. Mishra, J. Kotwal, and Mohan B. Agarwal. "Thrombotic Complications in Young Adults at High Altitude Areas: An Indian Experience." Blood 108, no. 11 (2006): 4108. http://dx.doi.org/10.1182/blood.v108.11.4108.4108.

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Abstract High altitudes(HA) have been a source of great adventures to sea land natives during short visits. But they also result in life threatening situations. There is no definite protocol to predict these likely complications. Certain thrombotic tendencies have been identified as possible risks for these complications but there have been some times such complications can occur in the individuals otherwise not known to have any known abnormalities of thrombosis. Also the duration of exposure to high altitude required to trigger this complication is uncertain. We present 24 cases of high alti

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Hristych, T. M., and D. O. Hontsariuk. "Pancreatic diseases and thrombotic, thromboembolic complications." Herald of Pancreatic Club 65, no. 4 (2024): 33–39. https://doi.org/10.33149/vkp.2024.04.06.

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In this paper, the authors analyze the etiologic, pathogenetic, and clinical variants of thrombotic and thromboembolic complications in chronic pancreatitis and pancreatic cancer. The authors concentrate on the pathogenetic mechanisms that contribute to the development of chronic pancreatitis, hereditary pancreatitis, and pancreatic cancer. These mechanisms include participation in systemic chronic inflammation, activation of plasma cells that accelerate proliferation, progression, migration, and invasion of epithelial cancer cells, metastasis of tumor cells, and a worsening of the response to

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Dragunova, Marina Alexandrovna, Ekaterina Sergeevna Sitkova, Oksana Nikolaevna Ogurkova, Roman Efimovich Batalov, and Tatiana Evgenievna Suslova. "ANALYSIS OF MARKERS OF THE HEMOSTASIS SYSTEM IN PATIENTS WITH NON-VALVULAR ATRIAL FIBRILLATION WITH THROMBOEMBOLIC COMPLICATIONS." Baikal Medical Journal 2, no. 3 (2023): 54–55. http://dx.doi.org/10.57256/2949-0715-2023-3-54-55.

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Introduction. Atrial fibrillation (AF) is one of the most common heart rhythm disorders. The risk of developing thromboembolic complications, including ischemic stroke, in patients with AF is 5 times higher than that in patients with sinus rhythm; therefore, one of the main directions in the treatment of patients with this rhythm disorder is the prevention of thromboembolic complications. Objective: to study the markers of monitoring the blood coagulation system in the blood serum of patients with non-valvular AF receiving anticoagulant therapy and having a history of thrombotic and thromboemb

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Inoue, Susumu, and Christina Anagonye. "Frequency of Thrombotic Events in Hospitalized Patients with Sickle Cell Disease." Blood 136, Supplement 1 (2020): 13. http://dx.doi.org/10.1182/blood-2020-143444.

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Background Thrombosis is one of the most common complications described in patients with sickle cell disease. However, little is known about the prevalence, variety and severity of thrombus particularly in sickle cell patients hospitalized with vaso-occlusive crisis. Methods We made a retrospective chart review of patients (age 21 years or older) admitted with sickle cell disease at Hurley Medical Center (Flint, Michigan) and was diagnosed with a thrombotic event between April 2012 and April 2020. To obtain a logistic model, we identified all patients with the the final discharge diagnosis of

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Linnemann and Lindhoff-Last. "Risk factors, management and primary prevention of thrombotic complications related to the use of central venous catheters." Vasa 41, no. 5 (2012): 319–32. http://dx.doi.org/10.1024/0301-1526/a000217.

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An adequate vascular access is of importance for the treatment of patients with cancer and complex illnesses in the intensive, perioperative or palliative care setting. Deep vein thrombosis and thrombotic occlusion are the most common complications attributed to central venous catheters in short-term and, especially, in long-term use. In this review we will focus on the risk factors, management and prevention strategies of catheter-related thrombosis and occlusion. Due to the lack of randomised controlled trials, there is still controversy about the optimal treatment of catheter-related thromb

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Ameri, Afshin, Courtney M. Anderson, Joetta H. Smith, and Julisa Patel. "Thromboembolic Complications in a Pediatric Patient Population: Treatment with Direct Oral Anticoagulants. Monitoring of Treatment Efficiency with D-Dimer Levels and Safety Profile By Thromboelastogram." Blood 138, Supplement 1 (2021): 4270. http://dx.doi.org/10.1182/blood-2021-146948.

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Abstract Direct oral anticoagulants (DOAC) such as the thrombin inhibitor Dabigatran and the coagulation factor Xa inhibitors Apixaban and Rivaroxaban have been in clinical use for the past 5-6 years. Familiarity with their use in the general pediatric population with thrombosis secondary to inflammatory disorders and rheumatologic disease is currently not as prevalent due to the widespread more conventional anticoagulation practice with the fractionated heparins in particular Lovenox. In this report we would like to summarize our experience in a pediatric patient population ranging from 3- 17

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Popovich, Yaroslav M., Vyacheslav V. Korsak, Patricia O. Boldizhar, and Orest P. Laver. "Surgical Prevention of Thromboembolic Complications in Transfascial Thrombosis." Ukrainian Journal of Cardiovascular Surgery 31, no. 1 (2023): 66–73. http://dx.doi.org/10.30702/ujcvs/23.31(01)/pk002-6673.

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The aim. To evaluate the effectiveness of surgical methods of prevention of venous thromboembolic complications in transfascial thrombosis of the lower extremities. Materials and methods. The paper analyzes the results of examination and surgical or conservative treatment of 417 patients with transfascial thrombosis treated at the Vascular Surgery Department of the Zakarpattia Regional Clinical Hospital named after A. Novak from 1995 to March 2020 and at the Surgical Department of the Central City Clinical Hospital of Uzhhorod from September 2020 to September 2022. The main (I) group con

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Park, D. J., S. E. Choi, H. Xu, J. H. Kang, and S. S. Lee. "AB0442 RISK FACTORS ASSOCIATED WITH THROMBOTIC EVENTS IN KOREAN PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS." Annals of the Rheumatic Diseases 79, Suppl 1 (2020): 1519.3–1520. http://dx.doi.org/10.1136/annrheumdis-2020-eular.1674.

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Background:Objectives:Up to 30~40% of all patients with systemic lupus erythematosus (SLE) experience thrombosis, presenting as stroke and myocardial infarction, and these thrombotic events cause substantial morbidity and mortality in SLE. We explored the risk factors associated with the occurrence of thrombotic events in SLE patients.Methods:This study enrolled 259 SLE patients (mean age, 34.0 ± 13.7; 239 females) with available clinical data at the time of SLE onset from the lupus cohort at Chonnam National University Hospital. Sociodemographic, clinical, and laboratory data, and history of

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Bereziuk, Olha M., Julia V. Mazur, Galyna K. Berko та ін. "PRIMARY AND SECONDARY THROMBOPHILIА: PATHOGENESIS, CLINICAL PRESENTATION, APPROACHES TO THROMBOTIC COMPLICATIONS PREVENTION AND TREATMENT". Wiadomości Lekarskie 72, № 5 (2019): 908–13. http://dx.doi.org/10.36740/wlek201905133.

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Introduction: Thrombophiliа is a predisposition to arterial or venous thrombotic complications as a result of congenital or acquired hemostatic system defects. Thrombophilia increases risk of fatal complications, disability of patients. The assessment of the risk of thrombotic complications makes it possible to prescribe adequate primary or secondary prophylaxis. However, there is no systematic information about estimation risk of thrombosis in various types of thrombophilia and conduction primary and secondary prophylaxis of thrombotic complications, choosing treatment. The aim: Analysis and

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Ouchicha, I., H. Abid, S. Bahja, et al. "THROMBOEMBOLIC COMPLICATIONS IN CHRONIC INFLAMMATORY BOWEL DISEASE." International Journal of Advanced Research 10, no. 04 (2022): 01–06. http://dx.doi.org/10.21474/ijar01/14509.

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Patients with chronic inflammatory bowel disease (IBD) represented by Crohn disease (CD) and ulcerative colitis (UC) are at higher risk for thromboembolic complications (CTE) which are a major cause of morbidity. They are attributed to a pre-thrombotic state induced by the inflammatory activity of this disease. The thrombotic risk inpatients with IBD is underestimated and thromboprophylaxisis not widely implemented in the clinical practice. Many studies on thromboembolism in the IBD populationhave already been carried out, however the precisepathogenesis is still poorly understood. The aim of

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Ouchicha, I., H. Abid, S. Bahja, et al. "THROMBOEMBOLIC COMPLICATIONS IN CHRONIC INFLAMMATORY BOWEL DISEASE." International Journal of Advanced Research 10, no. 04 (2022): 01–06. http://dx.doi.org/10.21474/ijar01/14509.

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Patients with chronic inflammatory bowel disease (IBD) represented by Crohn disease (CD) and ulcerative colitis (UC) are at higher risk for thromboembolic complications (CTE) which are a major cause of morbidity. They are attributed to a pre-thrombotic state induced by the inflammatory activity of this disease. The thrombotic risk inpatients with IBD is underestimated and thromboprophylaxisis not widely implemented in the clinical practice. Many studies on thromboembolism in the IBD populationhave already been carried out, however the precisepathogenesis is still poorly understood. The aim of

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Ouchicha, I., H. Abid, S. Bahja, et al. "THROMBOEMBOLIC COMPLICATIONS IN CHRONIC INFLAMMATORY BOWEL DISEASE." International Journal of Advanced Research 10, no. 04 (2022): 01–06. http://dx.doi.org/10.21474/ijar01/14509.

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Patients with chronic inflammatory bowel disease (IBD) represented by Crohn disease (CD) and ulcerative colitis (UC) are at higher risk for thromboembolic complications (CTE) which are a major cause of morbidity. They are attributed to a pre-thrombotic state induced by the inflammatory activity of this disease. The thrombotic risk inpatients with IBD is underestimated and thromboprophylaxisis not widely implemented in the clinical practice. Many studies on thromboembolism in the IBD populationhave already been carried out, however the precisepathogenesis is still poorly understood. The aim of

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Baygozina, E. А. "Combination of arterial and venous thrombosis in a patient with the novel coronavirus infection (a clinical case)." Tuberculosis and Lung Diseases 100, no. 4 (2022): 22–25. http://dx.doi.org/10.21292/2075-1230-2022-100-4-22-25.

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The presented clinical case demonstrates a rare combination of arterial and venous thrombosis in a patient with severe COVID-19 coronavirus infection and a fatal outcome. The clinical manifestations of thrombosis were acute irreversible ischemia of the lower extremities, acute impairment of cerebral circulation, and venous thrombosis of the left lower extremity. These thrombotic complications were caused by virus-induced coagulopathy deteriorated by such risk factors as an old age, comorbidities and delayed prescription of anticoagulants. The mechanisms of thrombotic complications in patients

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Drapkina, O. M., I. I. Almazova, A. V. Smirnova, S. A. Berns, and R. N. Shepel. "Cerebrovascular Accident in a Patient with Polycythemia: a Case Report." Rational Pharmacotherapy in Cardiology 18, no. 1 (2022): 79–84. http://dx.doi.org/10.20996/1819-6446-2022-02-10.

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Polycythemia vera is not only a clonal disease that causes hematopoietic stem cells, but also a pathology that often leads to thrombotic complications. Thrombosis can have different localization and is clinically manifested by stroke, myocardial infarction, deep vein thrombosis of the lower extremities, pulmonary embolism, thrombosis of the veins of internal organs and other conditions. One of the most formidable thrombotic complications is acute cerebrovascular accident. The heterogeneity of the possible causes of acute cerebrovascular accident requires a careful approach to differential diag

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Zafren, Ken. "Thrombotic Complications at Altitude." Wilderness & Environmental Medicine 15, no. 2 (2004): 155. http://dx.doi.org/10.1580/1080-6032(2004)015[0157:tcaa]2.0.co;2.

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Willerson, James T. "Serotonin and Thrombotic Complications." Journal of Cardiovascular Pharmacology 17, Supplement 5 (1991): S21. http://dx.doi.org/10.1097/00005344-199100175-00004.

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Czap, Alexandra L., Ashley Becker, and Patrick Y. Wen. "Thrombotic Complications in Gliomas." Seminars in Thrombosis and Hemostasis 45, no. 04 (2019): 326–33. http://dx.doi.org/10.1055/s-0039-1687892.

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AbstractArterial and venous thromboses are common in glioma patients, both in the perioperative period and throughout the course of the disease. High-grade glioma patients harbor underlying hypercoagulability, which predisposes these high-risk patients with prolonged immobility and neurologic deficits to thrombotic events. Despite the high incidence and recurrent nature of these complications, there is no standardized approach to the management of glioma patients, and many challenges remain. Historically, the perceived risk of intracranial and intratumoral hemorrhage limited the use of anticoa

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Ogurkova, O. N., Yu G. Lugacheva, M. A. Dragunova, and E. S. Sitkova. "Gender differences in serum markers of inflammation and platelet activation in patients with non-valvular atrial fibrillation." Medical Immunology (Russia) 25, no. 4 (2023): 947–54. http://dx.doi.org/10.15789/1563-0625-gdi-2695.

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The prevalence of atrial fibrillation is high and comparable in both sexes. Such factors as differently expressed blood biomarkers in women and men may play a role in the occurrence of atrial fibrillation and the development of thrombotic complications. To study markers of inflammation and platelet activation in patients with atrial fibrillation of non-valvular origin, receiving anticoagulant therapy and having a history of thrombotic complications and patients with atrial fibrillation without thrombotic complications, depending on the gender of the patients. The study included 22 healthy volu

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Werner, Maureen J. M., Ruben H. J. de Kleine, Marieke T. de Boer, et al. "Routine Postoperative Antithrombotic Therapy in Pediatric Liver Transplantation: Impact on Bleeding and Thrombotic Complications." Thrombosis and Haemostasis 120, no. 04 (2020): 627–37. http://dx.doi.org/10.1055/s-0039-1701010.

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Abstract Background Hepatic artery thrombosis (HAT) and portal vein thrombosis (PVT) are serious causes of morbidity and mortality after pediatric liver transplantation. To reduce thrombotic complications, routine antithrombotic therapy consisting of 1 week heparin followed by 3 months acetylsalicylic acid, was implemented in our pediatric liver transplant program in 2003. This study aimed to evaluate incidences of bleeding and thrombotic complications since the implementation of routine antithrombotic therapy and to identify risk factors for these complications. Methods This retrospective coh

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