Academic literature on the topic 'Transcription factor genes'

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Dissertations / Theses on the topic "Transcription factor genes"

1

Riaño-Pachón, Diego Mauricio. "Identification of transcription factor genes in plants." Phd thesis, Universität Potsdam, 2008. http://opus.kobv.de/ubp/volltexte/2008/2700/.

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In order to function properly, organisms have a complex control mechanism, in which a given gene is expressed at a particular time and place. One way to achieve this control is to regulate the initiation of transcription. This step requires the assembly of several components, i.e., a basal/general machinery common to all expressed genes, and a specific/regulatory machinery, which differs among genes and is the responsible for proper gene expression in response to environmental or developmental signals. This specific machinery is composed of transcription factors (TFs), which can be grouped int
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2

Harris, Robert. "The regulation of the embryonic transcription factor Pax-3." Thesis, University of Southampton, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.342629.

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3

Kannangara, Rubini Maya. "Identification of transcription factor target genes in Arabidopsis thaliana." Thesis, University of York, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.444343.

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4

Wiseman, Elizabeth Fiona. "Novel FOXM1 transcription factor target genes in oesophageal cancer." Thesis, University of Manchester, 2014. https://www.research.manchester.ac.uk/portal/en/theses/novel-foxm1-transcription-factor-target-genes-in-oesophageal-cancer(24278706-fa41-41b9-bf59-1902b1c4ba3d).html.

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The prognosis of oesophageal cancer remains poor, with <10% 5-year survival. Delineating the molecular pathogenesis of oesophageal cancer could inform future research into targeted therapies and may uncover novel biomarkers to aid management decisions. As a transcription factor with important roles in the control of cell cycle transcription, FOXM1 regulates cellular proliferation and chromosome stability. FOXM1 is frequently overexpressed in human cancers and this has recently been described in oesophageal adenocarcinoma (OAC) tissues. We have sought to identify novel gene targets of FOXM1 to
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5

Wang, Tianyuan. "Identifying Transcription Factor Targets and Studying Human Complex Disease Genes." NCSU, 2009. http://www.lib.ncsu.edu/theses/available/etd-03132009-120540/.

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Transcription factors (TFs) have been characterized as mediators of human complex disease processes. The target genes of TFs also may be associated with disease. Identification of potential TF targets could further our understanding of gene-gene interactions underlying complex disease. We focused on two TFs, USF1 and ZNF217, because of their biological importance, especially their known genetic association with coronary artery disease (CAD), and the availability of chromatin immunoprecipitation microarray (ChIP-chip) results. First, we used USF1 ChIP-chip data as a training dataset to develop
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6

Nickel, Gabrielle Celeste. "Positive Selection in Transcription Factor Genes Along the Human Lineage." Case Western Reserve University School of Graduate Studies / OhioLINK, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=case1220370670.

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7

Ellison, Jason. "Identification of target genes of PEA3, an ETS family transcription factor /." *McMaster only, 2001.

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8

Wang, Dongfang, Changqing Zhang, David Hearn, et al. "Identification of transcription-factor genes expressed in the Arabidopsis female gametophyte." BioMed Central, 2010. http://hdl.handle.net/10150/610082.

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BACKGROUND:In flowering plants, the female gametophyte is typically a seven-celled structure with four cell types: the egg cell, the central cell, the synergid cells, and the antipodal cells. These cells perform essential functions required for double fertilization and early seed development. Differentiation of these distinct cell types likely involves coordinated changes in gene expression regulated by transcription factors. Therefore, understanding female gametophyte cell differentiation and function will require dissection of the gene regulatory networks operating in each of the cell types.
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9

Parmar, Vipulkumar Mohanlal. "Transcriptional regulation of metabolic genes by the basic leucine zipper transcription factor Hac1ip and nutrient stimuli." Thesis, Durham University, 2012. http://etheses.dur.ac.uk/3415/.

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Saccharomyces cerevisiae cells respond to nutrients in their environment by altering their metabolic and transcriptional state in order to optimise the use of available nutrients and decide which of the several developmental pathways to pursue. In the yeast S. cerevisiae, meiosis and pseudohyphal growth are two major differentiation outcomes in response to nitrogen starvation. A central component of unfolded protein response pathway, the bZIP transcription factor Hac1ip, negatively regulates meiosis and pseudohyphal growth. The present study investigates this negative regulatory mechanism at e
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10

Fung, Khe Cheong Frederic, and 馮啟昌. "Upregulation of PITX2 transcription factor is associated with ovarian tumorigenesis." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2011. http://hub.hku.hk/bib/B45988183.

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