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Dissertations / Theses on the topic 'Trauma hemorrhagic shock'

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1

Talving, Peep. "Aspects of hepatoduodenal trauma and fluid therapy in hemorrhagic shock /." Stockholm, 2006. http://diss.kib.ki.se/2006/91-7140-740-5/.

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2

Alexander, Geoffrey C. "The Effect of Adding Drag-Reducing Polymers to Resuscitation Fluid During Hemorrhagic Shock on Skeletal Muscle Microcirculation." VCU Scholars Compass, 2006. http://scholarscompass.vcu.edu/etd/1522.

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Previous studies have shown an increase in survival when a minute amount of drag-reducing polymers were added to a resuscitation fluid. The purpose of this investigation was to examine the effect of adding a minute amount of the drag-reducing polymer polyethylene glycol to a resuscitation fluid, on the microcirculation of skeletal muscle during a volume-controlled hemorrhage model. The spinotrapezius muscle in twelve male Sprague Dawley rats was exteriorized for microvascular measurements of the arterioles. The diameters of the three levels of arterioles, interstitial fluid PO2, and RBC veloc
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3

Labruto, Fausto. "Modifications of cardiovascular response to ischemia and trauma /." Stockholm, 2005. http://diss.kib.ki.se/2005/91-7140-379-5/.

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4

Ji, Soo-Yeon. "COMPUTER-AIDED TRAUMA DECISION MAKING USING MACHINE LEARNING AND SIGNAL PROCESSING." VCU Scholars Compass, 2008. http://scholarscompass.vcu.edu/etd/1628.

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Over the last 20 years, much work has focused on computer-aided clinical decision support systems due to a rapid increase in the need for management and processing of medical knowledge. Among all fields of medicine, trauma care has the highest need for proper information management due to the high prevalence of complex, life-threatening injuries. In particular, hemorrhage, which is encountered in most traumatic injuries, is a dominant factor in determining survival in both civilian and military settings. This complication can be better managed using a more in-depth analysis of patient informat
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5

Lundin, Sandra, and Jonas Molin. "Räddar liv eller slösar tid? : prehospital vätskebehandlings effekter på patienter i hemorragisk chock." Thesis, Sophiahemmet Högskola, 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:shh:diva-3742.

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Trauma är den ledande dödsorsaken i Sverige för människor mellan 15 och 44 år och en stor andel dör till följd av blödning som uppkommer vid skadetillfället. Blödning fortsätter också vara den ledande orsaken till traumarelaterad död som kunde ha varit förebyggbar både civilt och militärt. Traumaomhändertagandet är komplext, ofta tidskritiskt och ambulanspersonalen är ofta de som först får vårda dessa patienter ute på skadeplats och därav blir ambulanspersonalens första bedömning och omhändertagande av stor betydelse. Vätskebehandling för kritiskt skadade traumapatienter i hemorragisk chock el
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6

Dufour-Gaume, Frédérique. "Enjeux, préparation et évaluation de produits sanguins labiles innovants adaptés aux blessés de guerre." Electronic Thesis or Diss., université Paris-Saclay, 2023. http://www.theses.fr/2023UPASQ076.

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Le blessé de guerre est un blessé grave qui associe choc hémorragique et polytraumatisme. Malgré les progrès thérapeutiques des dernières années, l'hémorragie reste la première cause de décès évitable chez ce type de blessés. Les patients qui survivent aux premières heures de leurs blessures voient leur pronostic vital et fonctionnel menacé par les complications secondaires. Les protocoles de prise en charge des blessés de guerre basés sur le principe de damage control ressuscitation et la transfusion massive de sang total ont permis de réduire considérablement les décès par choc hémorragique.
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7

Bergis, Benjamin. "Choc hémorragique traumatique et rhabdomyolyse : caractérisation d'une synergie lésionnelle délétère et prévention de l'insuffisance rénale aiguë post-traumatique." Electronic Thesis or Diss., Université Paris Cité, 2025. http://www.theses.fr/2025UNIP5005.

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Le choc hémorragique et la rhabdomyolyse sont deux causes majeures d'insuffisance rénale aiguë (IRA) dans les suites d'un traumatisme sévère. Bien qu'ils soient souvent associés, leurs effets combinés sur la perfusion, l'oxygénation, la fonction et la morphologie rénales demeurent méconnus. Des études expérimentales ont mis en évidence une synergie délétère entre ces deux agressions sur le rein, aggravant les paramètres de fonction et de perfusion rénale. Parmi les mécanismes possibles, la myoglobine, une métalloprotéine libérée en grande quantité lors de la rhabdomyolyse, semble jouer un rôle
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8

Prunet, Bertrand. "Contusion pulmonaire : aspects physiopathologiques et conséquences thérapeutiques." Thesis, Aix-Marseille, 2015. http://www.theses.fr/2015AIXM5001.

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L’association lésionnelle d’une contusion pulmonaire et d’un état de choc hémorragique est fréquente et constitue un réel chalenge thérapeutique. La prise en charge de ce choc va nécessiter une réanimation hémodynamique dans laquelle le remplissage vasculaire tient une place centrale. Mais dans ce contexte de poumon contus, il devra être raisonné car délétère sur le plan pulmonaire, notamment en terme d'oedème et d'altération de la compliance. Ce remplissage devra donc être titré, basé sur des objectifs tensionnels clairs et un monitorage hémodynamique fiable. L'utilisation de solutés à haut p
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9

Morrison, C. Anne Horwitz Irwin Hwang Lu-Yu. "Hypotensive resuscitation versus standard fluid resuscitation for the management of trauma patients in hemorrhagic shock : the safety phase of a randomized controlled trial." 2009. http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqdiss&rft_dat=xri:pqdiss:1465583.

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10

Fraga, Caroline Anne Pires. "The use of Tranexamic acid in trauma patients with hemorrhagic shock - a retrospective study in a tertiary care hospital." Master's thesis, 2020. https://hdl.handle.net/10216/128787.

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Introdução - O choque hemorrágico é a maior complicação e causa de morbi-mortalidade em doentes com trauma. Neste estudo, pretendemos avaliar o impacto do ácido tranexâmico em doentes com choque hemorrágico por trauma num hospital terciário. Material e métodos - Este estudo, realizado no Centro Hospitalar e Universitário São João, incluiu doentes adultos, admitidos no Serviço de Medicina Intensiva, por choque hemorrágico secundário a trauma. Definimos choque hemorrágico como pressão arterial sistólica ≤90 mmHg e/ou frequência cardíaca ≥110 bpm. Na ausência destes parâmetros, prevaleceu o juízo
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11

Fraga, Caroline Anne Pires. "The use of Tranexamic acid in trauma patients with hemorrhagic shock - a retrospective study in a tertiary care hospital." Dissertação, 2020. https://hdl.handle.net/10216/128787.

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Introdução - O choque hemorrágico é a maior complicação e causa de morbi-mortalidade em doentes com trauma. Neste estudo, pretendemos avaliar o impacto do ácido tranexâmico em doentes com choque hemorrágico por trauma num hospital terciário. Material e métodos - Este estudo, realizado no Centro Hospitalar e Universitário São João, incluiu doentes adultos, admitidos no Serviço de Medicina Intensiva, por choque hemorrágico secundário a trauma. Definimos choque hemorrágico como pressão arterial sistólica ≤90 mmHg e/ou frequência cardíaca ≥110 bpm. Na ausência destes parâmetros, prevaleceu o juízo
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12

Powers, Kinga Antonina. "Cellular Mechanisms of the Systemic Inflammatory Response Following Resuscitated Hemorrhagic Shock: The Role of Reactive Oxygen Species and Toll-like Receptor 4." Thesis, 2008. http://hdl.handle.net/1807/11247.

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Acute Respiratory Distress Syndrome (ARDS) following hemorrhagic shock/resuscitation (S/R) is an important contributor to late morbidity and mortality in trauma patients. S/R promotes ARDS by inducing oxidative stress that primes cells of the innate immune system for excessive responsiveness to small inflammatory stimuli, termed the “twohit” hypothesis. Activated alveolar macrophages (AM) play a central role and when recovered from S/R animals exhibit an exaggerated responsiveness to lipopolysaccharide (LPS) with increased activation of the proinflammatory transcription factor NF-κB, and augme
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13

LIN, YU-HSIN, and 林郁馨. "The effects of glutamine and multiple vitamin-supplemented resuscitation fluids on inflammatory response and target organ injury in rats with trauma and hemorrhagic shock." Thesis, 2016. http://ndltd.ncl.edu.tw/handle/19844509338706124053.

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碩士<br>輔仁大學<br>營養科學系碩士班<br>105<br>Hemorrhagic shock patients have huge loss of blood, may lead to energy and oxygen deficit and hypoxia. It shall be given as soon as possible to stop bleeding and fluid resuscitation. However, resuscitation may augment oxidative stress which leads to systemic inflammation, multiple organ failure, and even death. Recent studies indicated that antioxidant vitamins, energy metabolism-associated vitamins, and glutamine may alleviate oxidative stress, elevate energy synthesis, and provide energy for immune cells, respectively. Therefore, the aim of this study was to
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14

WU, YI-CHEN, and 吳怡蓁. "The effects of glutamine and fish oil-supplemented resuscitation fluids on inflammatory response and target organ injury in rats with trauma and hemorrhagic shock." Thesis, 2016. http://ndltd.ncl.edu.tw/handle/10494649989046827730.

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碩士<br>輔仁大學<br>營養科學系碩士班<br>105<br>Hemorrhagic shock is an emergent condition that usually caused by trauma, surgery, and parturition. When patients suffer from rapid blood loss, the hypovolemia may result in the decreases in energy and oxygen delivery which cause multiple organ failure (MOF). In clinical practice, patients are administered with resuscitation fluid rapidly to improve blood pressure and oxygen supply. However, resuscitation may elevate the production of reactive oxygen species (ROS) which induce inflammatory response and organ damages. Studies showed that fish oil have the anti-i
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15

Khazoom, François. "Rôle de l’acide urique dans la défaillance d’organes suite au choc hémorragique : une avenue thérapeutique?" Thesis, 2020. http://hdl.handle.net/1866/24497.

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Introduction: Alors que le choc hémorragique représente la première cause de mortalité précoce chez les patients subissant un traumatisme sévère, la défaillance d’organes est responsable d’une mortalité tardive chez cette population. Les alarmines, molécules libérées en situation d’ischémie-reperfusion et capables d’induire une réponse inflammatoire systémique et locale, représentent potentiellement une cible thérapeutique afin de minimiser la défaillance d’organes post-traumatique. L’acide urique est une molécule pro-inflammatoire et pro-apoptotique libérée en situation de choc hémorragique d
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16

Huang, Fu-Huan, and 黃富煥. "The investigation of trauma-hemorrhage shock induced inflammatory responses and organ damages in rats when arginine-, glutamine-, or amino acid mixture as resuscitation fluids." Thesis, 2018. http://ndltd.ncl.edu.tw/handle/w88utc.

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碩士<br>中山醫學大學<br>醫學研究所<br>106<br>Objective:Patients with trauma-hemorrhagic shock suffer from extensive blood loss and energy and oxygen deficiency that causes multiple organ failure and even death. To provide large volume of resuscitation fluid to recover blood pressure is the traditional clinical strategy; however, extensive production of free radicals may worsen the clinical outcome. We previously showed that arginine, citrulline, or glutamine may not alter inflammatory response in rats with hemorrhagic shock. Herein, we compared the impacts of arginine-, glutamine-, and amino acid mixture-s
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