Log in

Relevant bibliographies by topics / Unnatural amino acid mutagenesis / Journal articles

To see the other types of publications on this topic, follow the link: Unnatural amino acid mutagenesis.

Journal articles on the topic 'Unnatural amino acid mutagenesis'

Author: Grafiati

Published: 4 June 2021

Last updated: 12 February 2022

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 50 journal articles for your research on the topic 'Unnatural amino acid mutagenesis.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse journal articles on a wide variety of disciplines and organise your bibliography correctly.

1

Ravikumar, Yuvaraj, Saravanan Prabhu Nadarajan, Tae Hyeon Yoo, Chong-soon Lee, and Hyungdon Yun. "Unnatural amino acid mutagenesis-based enzyme engineering." Trends in Biotechnology 33, no. 8 (2015): 462–70. http://dx.doi.org/10.1016/j.tibtech.2015.05.002.

Full text

APA, Harvard, Vancouver, ISO, and other styles

2

Wang, Feng, Wei Niu, Jiantao Guo, and Peter G. Schultz. "Unnatural Amino Acid Mutagenesis of Fluorescent Proteins." Angewandte Chemie International Edition 51, no. 40 (2012): 10132–35. http://dx.doi.org/10.1002/anie.201204668.

Full text

APA, Harvard, Vancouver, ISO, and other styles

3

Wang, Feng, Wei Niu, Jiantao Guo, and Peter G. Schultz. "Unnatural Amino Acid Mutagenesis of Fluorescent Proteins." Angewandte Chemie 124, no. 40 (2012): 10279–82. http://dx.doi.org/10.1002/ange.201204668.

Full text

APA, Harvard, Vancouver, ISO, and other styles

4

Chin, Jason W., and Peter G. Schultz. "In Vivo Photocrosslinking with Unnatural Amino Acid Mutagenesis." ChemBioChem 3, no. 11 (2002): 1135–37. http://dx.doi.org/10.1002/1439-7633(20021104)3:11<1135::aid-cbic1135>3.0.co;2-m.

Full text

APA, Harvard, Vancouver, ISO, and other styles

5

Wang, Lei, Jianming Xie, Ashok A. Deniz, and Peter G. Schultz. "Unnatural Amino Acid Mutagenesis of Green Fluorescent Protein." Journal of Organic Chemistry 68, no. 1 (2003): 174–76. http://dx.doi.org/10.1021/jo026570u.

Full text

APA, Harvard, Vancouver, ISO, and other styles

6

Beene, Darren L., Dennis A. Dougherty, and Henry A. Lester. "Unnatural amino acid mutagenesis in mapping ion channel function." Current Opinion in Neurobiology 13, no. 3 (2003): 264–70. http://dx.doi.org/10.1016/s0959-4388(03)00068-0.

Full text

APA, Harvard, Vancouver, ISO, and other styles

7

Daggett, Kelly A., Mark Layer, and T. Ashton Cropp. "A General Method for Scanning Unnatural Amino Acid Mutagenesis." ACS Chemical Biology 4, no. 2 (2009): 109–13. http://dx.doi.org/10.1021/cb800271f.

Full text

APA, Harvard, Vancouver, ISO, and other styles

8

Anthony-Cahill, Spencer J., Michael C. Griffith, Christopher J. Noren, Daniel J. Suich, and Peter G. Schultz. "Site-specific mutagenesis with unnatural amino acids." Trends in Biochemical Sciences 14, no. 10 (1989): 400–403. http://dx.doi.org/10.1016/0968-0004(89)90287-9.

Full text

APA, Harvard, Vancouver, ISO, and other styles

9

Mendel, David, Jonathan A. Ellman, and Peter G. Schultz. "Construction of a light-activated protein by unnatural amino acid mutagenesis." Journal of the American Chemical Society 113, no. 7 (1991): 2758–60. http://dx.doi.org/10.1021/ja00007a063.

Full text

APA, Harvard, Vancouver, ISO, and other styles

10

Rust, Heather L., Venkataraman Subramanian, Graham M. West, Douglas D. Young, Peter G. Schultz, and Paul R. Thompson. "Using Unnatural Amino Acid Mutagenesis To Probe the Regulation of PRMT1." ACS Chemical Biology 9, no. 3 (2014): 649–55. http://dx.doi.org/10.1021/cb400859z.

Full text

APA, Harvard, Vancouver, ISO, and other styles

11

Young, Travis S., Insha Ahmad, Jun A. Yin, and Peter G. Schultz. "An Enhanced System for Unnatural Amino Acid Mutagenesis in E. coli." Journal of Molecular Biology 395, no. 2 (2010): 361–74. http://dx.doi.org/10.1016/j.jmb.2009.10.030.

Full text

APA, Harvard, Vancouver, ISO, and other styles

12

Ye, Shixin, Caroline Köhrer, Thomas Huber, et al. "Site-specific Incorporation of Keto Amino Acids into Functional G Protein-coupled Receptors Using Unnatural Amino Acid Mutagenesis." Journal of Biological Chemistry 283, no. 3 (2007): 1525–33. http://dx.doi.org/10.1074/jbc.m707355200.

Full text

Abstract:

G protein-coupled receptors (GPCRs) are ubiquitous heptahelical transmembrane proteins involved in a wide variety of signaling pathways. The work described here on application of unnatural amino acid mutagenesis to two GPCRs, the chemokine receptor CCR5 (a major co-receptor for the human immunodeficiency virus) and rhodopsin (the visual photoreceptor), adds a new dimension to studies of GPCRs. We incorporated the unnatural amino acids p-acetyl-l-phenylalanine (Acp) and p-benzoyl-l-phenylalanine (Bzp) into CCR5 at high efficiency in mammalian cells to produce functional receptors harboring reac

APA, Harvard, Vancouver, ISO, and other styles

13

Chatterjee, A., H. Xiao, M. Bollong, H. W. Ai, and P. G. Schultz. "Efficient viral delivery system for unnatural amino acid mutagenesis in mammalian cells." Proceedings of the National Academy of Sciences 110, no. 29 (2013): 11803–8. http://dx.doi.org/10.1073/pnas.1309584110.

Full text

APA, Harvard, Vancouver, ISO, and other styles

14

Valiyaveetil, Francis, Alexander Komarov, and Prasanna Devaraneni. "Testing Models for the Slow Inactivated State using Unnatural Amino Acid Mutagenesis." Biophysical Journal 102, no. 3 (2012): 530a. http://dx.doi.org/10.1016/j.bpj.2011.11.2895.

Full text

APA, Harvard, Vancouver, ISO, and other styles

15

Wang, Yanxin J., D. Miklos Szantai-Kis, and E. James Petersson. "Semi-synthesis of thioamide containing proteins." Organic & Biomolecular Chemistry 13, no. 18 (2015): 5074–81. http://dx.doi.org/10.1039/c5ob00224a.

Full text

Abstract:

To make thioamide protein folding experiments applicable to full-sized proteins, our laboratory has used a combination of native chemical ligation of thiopeptide fragments, unnatural amino acid mutagenesis to install fluorophore partners in expressed protein fragments, and chemoenzymatic protein modification to render these expressed protein ligations traceless.

APA, Harvard, Vancouver, ISO, and other styles

16

Baril, Stefanie A., Amber L. Koenig, Mackenzie W. Krone, et al. "Investigation of Trimethyllysine Binding by the HP1 Chromodomain via Unnatural Amino Acid Mutagenesis." Journal of the American Chemical Society 139, no. 48 (2017): 17253–56. http://dx.doi.org/10.1021/jacs.7b09223.

Full text

APA, Harvard, Vancouver, ISO, and other styles

17

England, Pamela M. "Unnatural Amino Acid Mutagenesis: A Precise Tool for Probing Protein Structure and Function†." Biochemistry 43, no. 37 (2004): 11623–29. http://dx.doi.org/10.1021/bi048862q.

Full text

APA, Harvard, Vancouver, ISO, and other styles

18

Chatterjee, Abhishek, Han Xiao, Peng-Yu Yang, Gautam Soundararajan, and Peter G. Schultz. "A Tryptophanyl-tRNA Synthetase/tRNA Pair for Unnatural Amino Acid Mutagenesis inE. coli." Angewandte Chemie International Edition 52, no. 19 (2013): 5106–9. http://dx.doi.org/10.1002/anie.201301094.

Full text

APA, Harvard, Vancouver, ISO, and other styles

19

Chatterjee, Abhishek, Han Xiao, Peng-Yu Yang, Gautam Soundararajan, and Peter G. Schultz. "A Tryptophanyl-tRNA Synthetase/tRNA Pair for Unnatural Amino Acid Mutagenesis inE. coli." Angewandte Chemie 125, no. 19 (2013): 5210–13. http://dx.doi.org/10.1002/ange.201301094.

Full text

APA, Harvard, Vancouver, ISO, and other styles

20

Poulsen, Mette H., Anahita Poshtiban, Viktoria Klippenstein, Valentina Ghisi, and Andrew J. R. Plested. "Gating modules of the AMPA receptor pore domain revealed by unnatural amino acid mutagenesis." Proceedings of the National Academy of Sciences 116, no. 27 (2019): 13358–67. http://dx.doi.org/10.1073/pnas.1818845116.

Full text

Abstract:

Ionotropic glutamate receptors (iGluRs) are responsible for fast synaptic transmission throughout the vertebrate nervous system. Conformational changes of the transmembrane domain (TMD) underlying ion channel activation and desensitization remain poorly understood. Here, we explored the dynamics of the TMD of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type iGluRs using genetically encoded unnatural amino acid (UAA) photocross-linkers, p-benzoyl-l-phenylalanine (BzF) and p-azido-l-phenylalanine (AzF). We introduced these UAAs at sites throughout the TMD of the GluA2 receptor an

APA, Harvard, Vancouver, ISO, and other styles

21

Chatterjee, Abhishek, Sophie B. Sun, Jennifer L. Furman, Han Xiao, and Peter G. Schultz. "A Versatile Platform for Single- and Multiple-Unnatural Amino Acid Mutagenesis in Escherichia coli." Biochemistry 52, no. 10 (2013): 1828–37. http://dx.doi.org/10.1021/bi4000244.

Full text

APA, Harvard, Vancouver, ISO, and other styles

22

Baker, Austin S., and Alexander Deiters. "Optical Control of Protein Function through Unnatural Amino Acid Mutagenesis and Other Optogenetic Approaches." ACS Chemical Biology 9, no. 7 (2014): 1398–407. http://dx.doi.org/10.1021/cb500176x.

Full text

APA, Harvard, Vancouver, ISO, and other styles

23

Kolev, Joshua N., Jacqueline M. Zaengle, Rajesh Ravikumar, and Rudi Fasan. "Enhancing the Efficiency and Regioselectivity of P450 Oxidation Catalysts by Unnatural Amino Acid Mutagenesis." ChemBioChem 15, no. 7 (2014): 1001–10. http://dx.doi.org/10.1002/cbic.201400060.

Full text

APA, Harvard, Vancouver, ISO, and other styles

24

Taupitz, Kim F., Wolfgang Dörner, and Henning D. Mootz. "Covalent Capturing of Transient SUMO-SIM Interactions Using Unnatural Amino Acid Mutagenesis and Photocrosslinking." Chemistry - A European Journal 23, no. 25 (2017): 5978–82. http://dx.doi.org/10.1002/chem.201605619.

Full text

APA, Harvard, Vancouver, ISO, and other styles

25

Kimata, Y., H. Shimada, T. Hirose, and Y. Ishimura. "Role of THR-252 in Cytochrome P450CAM: A Study with Unnatural Amino Acid Mutagenesis." Biochemical and Biophysical Research Communications 208, no. 1 (1995): 96–102. http://dx.doi.org/10.1006/bbrc.1995.1310.

Full text

APA, Harvard, Vancouver, ISO, and other styles

26

Barrett, J. E., C. M. Lucero, and P. G. Schultz. "A Model for Hydride Transfer in Thymidylate Synthase Based on Unnatural Amino Acid Mutagenesis." Journal of the American Chemical Society 121, no. 34 (1999): 7965–66. http://dx.doi.org/10.1021/ja991040+.

Full text

APA, Harvard, Vancouver, ISO, and other styles

27

Rudack, Till, Christian Teuber, Marvin Scherlo, et al. "The Ras dimer structure." Chemical Science 12, no. 23 (2021): 8178–89. http://dx.doi.org/10.1039/d1sc00957e.

Full text

Abstract:

By combining the incorporation of unnatural amino acids, click chemistry, FRET and EPR distance measurements, protein modeling and biomolecular simulations, we obtained an unambiguous Ras dimer structural model and disrupt the dimer by mutagenesis.

APA, Harvard, Vancouver, ISO, and other styles

28

Duffy, Noah H., Henry A. Lester, and Dennis A. Dougherty. "Ondansetron and Granisetron Binding Orientation in the 5-HT3Receptor Determined by Unnatural Amino Acid Mutagenesis." ACS Chemical Biology 7, no. 10 (2012): 1738–45. http://dx.doi.org/10.1021/cb300246j.

Full text

APA, Harvard, Vancouver, ISO, and other styles

29

Pavic, Karolina, Pablo Rios, Kristina Dzeyk, Christine Koehler, Edward A. Lemke, and Maja Köhn. "Unnatural Amino Acid Mutagenesis Reveals Dimerization As a Negative Regulatory Mechanism of VHR’s Phosphatase Activity." ACS Chemical Biology 9, no. 7 (2014): 1451–59. http://dx.doi.org/10.1021/cb500240n.

Full text

APA, Harvard, Vancouver, ISO, and other styles

30

Kolev, Joshua N., Jacqueline M. Zaengle, Rajesh Ravikumar, and Rudi Fasan. "Corrigendum: Enhancing the Efficiency and Regioselectivity of P450 Oxidation Catalysts by Unnatural Amino Acid Mutagenesis." ChemBioChem 15, no. 7 (2014): 913. http://dx.doi.org/10.1002/cbic.201400081.

Full text

APA, Harvard, Vancouver, ISO, and other styles

31

Arnam, Ethan B. Van, Kristina N. McCleary, Fan Liu, et al. "Investigation of Dopamine Receptor Structure and Function by Structure Prediction and Unnatural Amino Acid Mutagenesis." Biophysical Journal 102, no. 3 (2012): 247a. http://dx.doi.org/10.1016/j.bpj.2011.11.1361.

Full text

APA, Harvard, Vancouver, ISO, and other styles

32

Han, Sang-Woo, Eul-Soo Park, Joo-Young Dong та Jong-Shik Shin. "Active-Site Engineering of ω-Transaminase for Production of Unnatural Amino Acids Carrying a Side Chain Bulkier than an Ethyl Substituent". Applied and Environmental Microbiology 81, № 20 (2015): 6994–7002. http://dx.doi.org/10.1128/aem.01533-15.

Full text

Abstract:

ABSTRACTω-Transaminase (ω-TA) is a promising enzyme for use in the production of unnatural amino acids from keto acids using cheap amino donors such as isopropylamine. The small substrate-binding pocket of most ω-TAs permits entry of substituents no larger than an ethyl group, which presents a significant challenge to the preparation of structurally diverse unnatural amino acids. Here we report on the engineering of an (S)-selective ω-TA fromOchrobactrum anthropi(OATA) to reduce the steric constraint and thereby allow the small pocket to readily accept bulky substituents. On the basis of a doc

APA, Harvard, Vancouver, ISO, and other styles

33

Wynn, R., and F. M. Richards. "Unnatural amino acid packing mutants of Escherichia coli thioredoxin produced by combined mutagenesis/chemical modification techniques." Protein Science 2, no. 3 (1993): 395–403. http://dx.doi.org/10.1002/pro.5560020311.

Full text

APA, Harvard, Vancouver, ISO, and other styles

34

Wright, Tom H., and Benjamin G. Davis. "Post-translational mutagenesis for installation of natural and unnatural amino acid side chains into recombinant proteins." Nature Protocols 12, no. 10 (2017): 2243–50. http://dx.doi.org/10.1038/nprot.2017.087.

Full text

APA, Harvard, Vancouver, ISO, and other styles

35

Riederer, Erika A., and Francis I. Valiyaveetil. "Investigation of the allosteric coupling mechanism in a glutamate transporter homolog via unnatural amino acid mutagenesis." Proceedings of the National Academy of Sciences 116, no. 32 (2019): 15939–46. http://dx.doi.org/10.1073/pnas.1907852116.

Full text

Abstract:

Glutamate transporters harness the ionic gradients across cell membranes for the concentrative uptake of glutamate. The sodium-coupled Asp symporter, GltPh is an archaeal homolog of glutamate transporters and has been extensively used to understand the transport mechanism. A critical aspect of the transport cycle in GltPh is the coupled binding of sodium and aspartate. Previous studies have suggested a major role for hairpin-2 (HP2), which functions as the extracellular gate for the aspartate binding site, in the coupled binding of sodium and aspartate to GltPh. In this study, we develop a flu

APA, Harvard, Vancouver, ISO, and other styles

36

Koh, John T., Virginia W. Cornish, and Peter G. Schultz. "An Experimental Approach to Evaluating the Role of Backbone Interactions in Proteins Using Unnatural Amino Acid Mutagenesis†." Biochemistry 36, no. 38 (1997): 11314–22. http://dx.doi.org/10.1021/bi9707685.

Full text

APA, Harvard, Vancouver, ISO, and other styles

37

Naganathan, Saranga, Shixin Ye, Terence Duarte, Thomas Huber, Pallavi Sachdev, and Thomas P. Sakmar. "A Novel Method to Probe Membrane Protein Topology Using Unnatural Amino Acid Mutagenesis and Antibody Epitope Tagging." Biophysical Journal 98, no. 3 (2010): 419a. http://dx.doi.org/10.1016/j.bpj.2009.12.2263.

Full text

APA, Harvard, Vancouver, ISO, and other styles

38

Bentin, Thomas, Ramin Hamzavi, Johan Salomonsson, Hervé Roy, Michael Ibba, and Peter E. Nielsen. "Photoreactive Bicyclic Amino Acids as Substrates for MutantEscherichia coliPhenylalanyl-tRNA Synthetases." Journal of Biological Chemistry 279, no. 19 (2004): 19839–45. http://dx.doi.org/10.1074/jbc.m401278200.

Full text

Abstract:

Unnatural amino acids carrying reactive groups that can be selectively activated under non-invasive biologically benign conditions are of interest in protein engineering as biological tools for the analysis of protein-protein and protein-nucleic acids interactions. The double ring system phenylalanine analogues benzofuranylalanine and benzotriazolylalanine were synthesized, and their photolability was tested by UV irradiation at 254, 320, and 365 nm. Although both showed photo reactivity, benzofuranylalanine appeared as the most promising compound because this amino acid was activated by UVA (

APA, Harvard, Vancouver, ISO, and other styles

39

Kraut, Daniel A., Michael J. Churchill, Phillip E. Dawson, and Daniel Herschlag. "Evaluating the Potential for Halogen Bonding in the Oxyanion Hole of Ketosteroid Isomerase Using Unnatural Amino Acid Mutagenesis." ACS Chemical Biology 4, no. 4 (2009): 269–73. http://dx.doi.org/10.1021/cb900016q.

Full text

APA, Harvard, Vancouver, ISO, and other styles

40

Chatterjee, A., H. Xiao, and P. G. Schultz. "Evolution of multiple, mutually orthogonal prolyl-tRNA synthetase/tRNA pairs for unnatural amino acid mutagenesis in Escherichia coli." Proceedings of the National Academy of Sciences 109, no. 37 (2012): 14841–46. http://dx.doi.org/10.1073/pnas.1212454109.

Full text

APA, Harvard, Vancouver, ISO, and other styles

41

McMenimen, Kathryn A., E. James Petersson, Henry A. Lester, and Dennis A. Dougherty. "Probing the Mg2+ Blockade Site of an N-Methyl-d-aspartate (NMDA) Receptor with Unnatural Amino Acid Mutagenesis." ACS Chemical Biology 1, no. 4 (2006): 227–34. http://dx.doi.org/10.1021/cb6000944.

Full text

APA, Harvard, Vancouver, ISO, and other styles

42

Beene, D. L. "Tyrosine Residues That Control Binding and Gating in the 5-Hydroxytryptamine3 Receptor Revealed by Unnatural Amino Acid Mutagenesis." Journal of Neuroscience 24, no. 41 (2004): 9097–104. http://dx.doi.org/10.1523/jneurosci.2429-04.2004.

Full text

APA, Harvard, Vancouver, ISO, and other styles

43

Santoro, S. W. "An archaebacteria-derived glutamyl-tRNA synthetase and tRNA pair for unnatural amino acid mutagenesis of proteins in Escherichia coli." Nucleic Acids Research 31, no. 23 (2003): 6700–6709. http://dx.doi.org/10.1093/nar/gkg903.

Full text

APA, Harvard, Vancouver, ISO, and other styles

44

Ye, Shixin, Thomas Huber, and Thomas P. Sakmar. "Unnatural Amino Acid Mutagenesis For Site-specific Incorporation Of Keto And Azido Functionalities Into Functional G Protein-coupled Receptors." Biophysical Journal 96, no. 3 (2009): 632a. http://dx.doi.org/10.1016/j.bpj.2008.12.3343.

Full text

APA, Harvard, Vancouver, ISO, and other styles

45

Padgett, C. L., A. P. Hanek, H. A. Lester, D. A. Dougherty, and S. C. R. Lummis. "Unnatural Amino Acid Mutagenesis of the GABAA Receptor Binding Site Residues Reveals a Novel Cation- Interaction between GABA and 2Tyr97." Journal of Neuroscience 27, no. 4 (2007): 886–92. http://dx.doi.org/10.1523/jneurosci.4791-06.2007.

Full text

APA, Harvard, Vancouver, ISO, and other styles

46

Zheng, Yunan, Tommy L. Lewis, Peter Igo, Franck Polleux, and Abhishek Chatterjee. "Virus-Enabled Optimization and Delivery of the Genetic Machinery for Efficient Unnatural Amino Acid Mutagenesis in Mammalian Cells and Tissues." ACS Synthetic Biology 6, no. 1 (2016): 13–18. http://dx.doi.org/10.1021/acssynbio.6b00092.

Full text

APA, Harvard, Vancouver, ISO, and other styles

47

Wissner, Rebecca F., Solongo Batjargal, Colin M. Fadzen, and E. James Petersson. "Labeling Proteins with Fluorophore/Thioamide Förster Resonant Energy Transfer Pairs by Combining Unnatural Amino Acid Mutagenesis and Native Chemical Ligation." Journal of the American Chemical Society 135, no. 17 (2013): 6529–40. http://dx.doi.org/10.1021/ja4005943.

Full text

APA, Harvard, Vancouver, ISO, and other styles

48

Thorson, Jon S., Injae Shin, Eli Chapman, Gun Stenberg, Bengt Mannervik, and Peter G. Schultz. "Analysis of the Role of the Active Site Tyrosine in Human Glutathione Transferase A1-1 by Unnatural Amino Acid Mutagenesis." Journal of the American Chemical Society 120, no. 2 (1998): 451–52. http://dx.doi.org/10.1021/ja9731682.

Full text

APA, Harvard, Vancouver, ISO, and other styles

49

Cieplak, Andrzej Stanisław, and Nur Başak Sürmeli. "Single-Site Mutation and Secondary Structure Stability: An Isodesmic Reaction Approach. The Case of Unnatural Amino Acid Mutagenesis Ala→Lac." Journal of Organic Chemistry 69, no. 10 (2004): 3250–61. http://dx.doi.org/10.1021/jo0358372.

Full text

APA, Harvard, Vancouver, ISO, and other styles

50

Pless, Stephan A., Michael Yau, Jason D. Galpin, Christopher A. Ahern, and Harley T. Kurata. "Unnatural Amino Acid Mutagenesis Reveals the Critical Role of Hydrogen Bonding for Binding of Retigabine in the Pore of KCNQ Channels." Biophysical Journal 106, no. 2 (2014): 143a. http://dx.doi.org/10.1016/j.bpj.2013.11.828.

Full text

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!