Academic literature on the topic 'Uricosuria'

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Journal articles on the topic "Uricosuria"

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Turaeva, Nazira Yuldashevna, and Feruza Khamidovna Mamatkulova. "PREMORBIDE FEATURES OF INTERSTITIAL NEPHRITIS CURRENT IN CHILDREN WITH PURINE DYSMETABOLISM (CLINICAL-LABORATORY ASPECTS)." Multidisciplinary Journal of Science and Technology 4, no. 6 (2024): 201–5. https://doi.org/10.5281/zenodo.11652270.

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Purpose of the study. To study the clinical-laboratory features of the current interstitial nephritis in children developed against the background of hyperuricosuria and hyperuricosuria. Materials and methods. Examined 82 patients with a diagnosis interstitial nephritis of dysmetabolic genesis against uricosuria background of more than 1mg of uric acids per 1ml of urine. The metabolic status of patients was evaluated according to a special program, including genealogical analysis, screening tests and quantitative biochemicall Studies. Urichemy was defined as the main biochemical marker (>32
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Abraham, Paul A., Charles E. Halstenson, John A. Opsahl, Gary R. Matzke, and William F. Keane. "Suprofen-Induced Uricosuria." American Journal of Nephrology 8, no. 2 (1988): 90–95. http://dx.doi.org/10.1159/000167564.

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Gresser, U., U. Kronawitter, O. Adjan, and N. Zöllner. "Rapid onset of uricosuria after oral administration of irtemazole, an uricosuric substance." Klinische Wochenschrift 67, no. 20 (1989): 1058–60. http://dx.doi.org/10.1007/bf01727008.

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Golovanov, S. A., M. Yu Prosyannikov, A. V. Sivkov, N. V. Anokhin, D. A. Voytko, and V. V. Drozhzheva. "Metabolic risk factors and urinary stones formation. VII: Uricosuria lithogenic features in men and women." Experimental and Сlinical Urology 16, no. 3 (2023): 154–64. http://dx.doi.org/10.29188/2222-8543-2023-16-3-154-164.

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Introduction. Hyperuricosuria usually considered as the main metabolic factor in the formation of uric acid stones, but this issue remains unclear. Gender differences in the prevalence of urolithiasis (UL) indicate the need for a more detailed study of the lithogenic properties of uricosuria and its role in the development of various metabolic types of UL. In this study, was investigated the effect of varying degrees of uricosuria in men and women with UL on metabolic parameters and the frequency of detection of urinary stones of different chemical composition. Materials and methods. A total o
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P., Randrianavony, Reboza A.M., Quansah N., and Randimbivololona F. "Hypouricemic Activity of Pentopetia Androsaemifolia Decne. (Apocynaceae) Hydro Alcoholic Extract in Mice." European Scientific Journal, ESJ 13, no. 36 (2017): 340. http://dx.doi.org/10.19044/esj.2017.v13n36p340.

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The aim of this work was to investigate the uricemic and uricosuric activity of the hydro alcoholic extract of Pentopetia androsaemifolia in experimentally induced hyperuricemic mice. Hyperuricemia was induced in the mice by intraperitoneal injection of potassium oxonate. Oral administration of the extract at doses 50 to 200 mg/kg reduce hyperuricemia from 218.78 ± 7.50 to 72.29 ± 16.88 mg/l (P< 0. 05). The same doses of 50 to 200 mg/kg of the extract also reduce uricosuria from 125.4 ± 4.4 to 70 ± 12.6 mg/l (p< 0.05). A direct correlation exists between plasma uric acid concentration an
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Bombushkar, Igor. "Metabolic accompaniments of variants of uric acid exchange." Journal of Education, Health and Sport 12, no. 12 (2022): 373–90. http://dx.doi.org/10.12775/jehs.2022.12.12.054.

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Background. During the implementation of the project "Physiological activity of uric acid", our group discovered four variants of the combination of levels of uricemia and uricosuria in patients with chronic pyelonephritis in the remission phase, which are accompanied by characteristic constellations of parameters of the autonomic nervous, endocrine, and immune systems, the levels of which correlate with uricemia and/or uricosuria. The aim of this study is to clarify the relationship between parameters of exchange of uric acid and other metabolites. Materials and methods. Under an observations
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Zapf, Ava M., and Owen M. Woodward. "SGLT2 Inhibitors and Uric Acid Homeostasis." Gout, Urate, and Crystal Deposition Disease 2, no. 2 (2024): 157–72. http://dx.doi.org/10.3390/gucdd2020014.

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A relationship between metabolic disorders and hyperuricemia is well established. The nature of the relationship—risk factor, causal agent, or byproduct—remains unclear. Recent studies of sodium–glucose transporter 2 inhibitors (SGLT2i’s) have established that this pharmacological intervention is beneficial to patients with hyperglycemia and type 2 diabetes mellitus (T2D) and also against the common cardio and renal comorbidities associated with diabetes. Hyperuricemia, or high plasma uric acid levels, is one of the comorbidities mitigated with SGLT2i treatment, raising the potential for using
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Mukiy, Yu V., D. I. Bogomaz, and O. A. Pavlova. "Nephrolithiasis and uricosuria diagnostics in dogs." BIO Web of Conferences 66 (2023): 09004. http://dx.doi.org/10.1051/bioconf/20236609004.

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Nephrolithiasis and hyperuricosuria is a common pathology in dogs of various breeds. The problem of breeding lies in the fact that the diagnostic methods used: X-ray examination, determination of lipid composition in the blood and the urogenital microbiome, do not allow early diagnostics in young dogs before the onset of clinical changes, as well as to identify animals carrying mutant alleles of disease candidate genes. We have developed a test system for nephrolithiasis and uricosuria diagnostics in dogs, including primers and allele-selective probes. A control plasmid solution was used as a
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Bombushkar, Igor, Igor Popovych, and Walery Zukow. "Relationships between the parameters of uric acid exchange and electroencephalograms in humans." Journal of Education, Health and Sport 13, no. 3 (2023): 458–85. http://dx.doi.org/10.12775/jehs.2023.13.03.055.

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Background. During the implementation of the project "Physiological activity of uric acid", our group discovered four variants of the combination of levels of uricemia and uricosuria both in healthy rats and in people with chronic pyelonephritis and cholecystitis in the remission phase, which are accompanied by characteristic constellations of parameters of the autonomic nervous, endocrine, and immune systems, as well as the exchange of nitrogenous metabolites and electrolytes, the levels of which correlate with uricemia and/or uricosuria. The aim of this study is to clarify the relationship b
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Bombushkar, Igor, Anatoliy Gozhenko, Inna Korda, Nataliya Badiuk, Walery Zukow, and Igor Popovych. "Features of the exchange of electrolytes and nitrogenous metabolites under different options of uric acid exchange in healthy female rats." Journal of Education, Health and Sport 10, no. 4 (2020): 405–15. http://dx.doi.org/10.12775/jehs.2020.10.04.043.

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Background. We previously identified 4 variants-clusters of uricemia and uricosuria both in rats and in humans. It was shown that the clusters differ from each other in the constellation of immune, autonomic and endocrine parameters, which correlate with uricemia and uricosuria. The aim of this study was to identify the electrolytes and nitrogenous metabolites, the combination of which differentiates previously formed quantitative and qualitative variants of uric acid metabolism in rats. Materials and Methods. Experiment was performed on 60 healthy female Wistar rats 220-300 g. The plasma and
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Dissertations / Theses on the topic "Uricosuria"

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HSIEH, WEI-YANG, and 謝維洋. "Solubility Measurement for the Uricosuric Agents in Supercritical Carbon Dioxide." Thesis, 2017. http://ndltd.ncl.edu.tw/handle/29p8nz.

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碩士<br>國立臺灣科技大學<br>化學工程系<br>105<br>The solubilities of uricosuric agents (probenecid and sulfinpyrazone) and the second generation sulfonylurea drug (glibenclamide) in supercritical carbon dioxide are measured with a semi-flow type equilibrium apparatus at temperatures ranging from 313.2 K to 353.2 K and pressure from 15 MPa to 31 MPa. To ensure the output stream of equilibrium cell being saturated, the minimum contact time are 1500 s , 750 s , 1000 s for probenecid, sulfinpyrazone, glibenclamide, respectively. Over the experimental conditions, the solubilities are ranging from 0.13 × 10-5 ~ 1.
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Lin, Tsai-Pei, and 林采佩. "Capillary electrophoresis method for the analysis of antigout and uricosuric drugs." Thesis, 2005. http://ndltd.ncl.edu.tw/handle/53840231316507316224.

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碩士<br>高雄醫學大學<br>藥學研究所碩士班<br>93<br>Capillary electrophoresis method (CE) was studied for the simultaneous separation and quantitation of seven antigout and uricosuric drugs including allopurinol (AP), benzbromarone (BZB), orotic acid (OA), oxypurinol (OP), probenecid (PB) and sulfinpyrazone (SPZ). Capillary zone electrophoresis method (CZE) was first tried to the separation of the seven drugs. At the conditions of background electrolyte with borate buffer (50 mM; pH 9.00), applied voltage of 15 kV, untreated fused-silica capillary (40.2 cm, effective length 30 cm, 50 μm I.D.), hydrodynamic
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Books on the topic "Uricosuria"

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Walsh, Stephen B. Approach to the patient with renal tubular acidosis. Edited by Robert Unwin. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199592548.003.0036.

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The renal tubular acidoses are a collection of syndromes characterized by defective urinary acidification. These syndromes have classically caused some confusion, and many opine that the widely used numerical system (type 1, 2) should be abandoned. We consider distal renal tubular acidosis and proximal renal tubular acidosis separately, and briefly cover hypoaldosteronism. Distal (Type 1) renal tubular acidosis is a syndrome of hypokalaemia, metabolic acidosis, kidney stones, nephrocalcinosis, and osteomalacia or rickets. It is caused by failure of the acid secreting α‎‎‎-intercalated cells in
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Dalbeth, Nicola. Urate-lowering therapy agents. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780198748311.003.0009.

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Xanthine oxidase (allopurinol or febuxostat) is considered first-line urate-lowering therapy. Combination therapy with uricosuric agents may be required. The choice of urate-lowering therapy is dictated by co-morbidities, particularly renal and hepatic impairment. Appropriate monitoring for drug adverse effects as well as serum urate to ensure targets are achieved is required.
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Richette, Pascal. Principles of gout management. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199668847.003.0044.

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The general goals of gout therapy are to manage acute flares and to prevent recurrences and prevent or reverse the complications of urate deposition by lowering urate levels. The choice of drug should be made on the basis of the patient’s co-morbidities, other medications, and side effect profile. Treatment of flares can be achieved with non-steroidal anti-inflammatory drugs, colchicine, or corticosteroids (systemic or intra-articular). Interleukin-1 blockers could become an alternative in patients contraindicated for traditional anti-inflammatory agents. Lowering of urate levels below monosod
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Book chapters on the topic "Uricosuria"

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Hart, Susan Emeigh. "Uricosuric and Hypo-Uricemic Activity." In Drug Discovery and Evaluation: Pharmacological Assays. Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-05392-9_20.

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Hart, Susan Emeigh. "Uricosuric and Hypo-Uricemic Activity." In Drug Discovery and Evaluation: Pharmacological Assays. Springer Berlin Heidelberg, 2015. http://dx.doi.org/10.1007/978-3-642-27728-3_20-1.

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Dan, Takashi, Hiroshi Koga, Etsuro Onuma, Haruko Tanaka, Haruhiko Sato, and Bunya Aoki. "The Activity of AA-193, A New Uricosuric Agent, in Animals." In Advances in Experimental Medicine and Biology. Springer US, 1989. http://dx.doi.org/10.1007/978-1-4684-5673-8_50.

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Sigrist, G., J. Greven, and B. Fuchs. "Effects of the New Uricosuric Diuretic Bay r 4420 on Rat Kidney Function." In Diuretics: Basic, Pharmacological, and Clinical Aspects. Springer US, 1987. http://dx.doi.org/10.1007/978-1-4613-2067-8_140.

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Gresser, Ursula, Birgit S. Gathof, and Manfred Gross. "Benzbromarone and Fenofibrate are Lipid Lowering and Uricosuric: A Possible Key to Metabolic Syndrome?" In Purine and Pyrimidine Metabolism in Man VIII. Springer US, 1995. http://dx.doi.org/10.1007/978-1-4615-2584-4_22.

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Hosoyamada, Makoto, Kimiyoshi Ichida, Tatsuo Hosoya, and Hitoshi Endou. "Primary Renal Uricosuria." In Genetic Diseases of the Kidney. Elsevier, 2009. http://dx.doi.org/10.1016/b978-0-12-449851-8.00009-7.

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Sayer, John A., and Fiona E. Karet. "The renal tubular acidoses." In Oxford Textbook of Medicine, edited by John D. Firth. Oxford University Press, 2020. http://dx.doi.org/10.1093/med/9780198746690.003.0505.

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Renal tubular acidosis (RTA) arises when the kidneys either fail to excrete sufficient acid, or are unable to conserve bicarbonate, with both circumstances leading to metabolic acidosis of varying severity with altered serum potassium. Proximal and distal types of RTA can be differentiated according to which nephron segment is malfunctioning. Proximal RTA: aetiology and diagnosis—the condition may be (1) secondary to generalized proximal tubular dysfunction (part of the renal Fanconi’s syndrome), or rarely (2) due to an inherited mutation of a single transporter (NBC1) located at the basolater
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Enna, S. J., and David B. Bylund. "Uricosuric Agents." In xPharm: The Comprehensive Pharmacology Reference. Elsevier, 2007. http://dx.doi.org/10.1016/b978-008055232-3.63837-1.

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"Uricosuric Therapy." In Crystal-Induced Arthropathies. CRC Press, 2006. http://dx.doi.org/10.3109/9781420020632-26.

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"uricosuric, adj." In Oxford English Dictionary, 3rd ed. Oxford University Press, 2023. http://dx.doi.org/10.1093/oed/2101826820.

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Conference papers on the topic "Uricosuria"

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Perez-Ruiz, F., P. Kandaswamy, R. Karra Gurunath, H. Burton, and T. Jansen. "SAT0360 A summary of clinical evidence for commonly used uricosurics for gout in europe." In Annual European Congress of Rheumatology, EULAR 2018, Amsterdam, 13–16 June 2018. BMJ Publishing Group Ltd and European League Against Rheumatism, 2018. http://dx.doi.org/10.1136/annrheumdis-2018-eular.3026.

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