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Journal articles on the topic 'Uterine myoma'

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1

Markowska, Anna, Mateusz de Mezer, Paweł Kurzawa, et al. "Analysis of Expression of the ANG1, CaSR and FAK Proteins in Uterine Fibroids." International Journal of Molecular Sciences 25, no. 13 (2024): 7164. http://dx.doi.org/10.3390/ijms25137164.

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Understanding the molecular factors involved in the development of uterine myomas may result in the use of pharmacological drugs instead of aggressive surgical treatment. ANG1, CaSR, and FAK were examined in myoma and peripheral tissue samples taken from women after myoma surgery and in normal uterine muscle tissue samples taken from the control group. Tests were performed using tissue microarray immunohistochemistry. No statistically significant differences in ANG1 expression between the tissue of the myoma, the periphery, and the normal uterine muscle tissue of the control group were recorde
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2

Adi Susianto, Indra, Ferry Santoso, Iwan Prasetyo, Diana Novitasari, Dimas Sindhu Wibisono, and Jerry Ferdinand Haposan Saragih. "Successful Repair Management for Urinary Bladder Perforation During Myomectomy on Cervical Myoma on Patients with Previous Cesarean Section: A Challenging Case Report." Indonesian Journal of Obstetrics & Gynecology Science 6, no. 2 (2023): 313–18. http://dx.doi.org/10.24198/obgynia/v6.n2.497.

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The 20-25% incidence of uterine myoma often experienced by women in childbearing age and 2% of these uterine myomas attach and grow in the uterine cervical area. The chief complain of cervical myom are lumps in the lower abdomen that are getting bigger and pressing on the urinary bladder cause difficulty in urinating and are accompanied by bloody urine, although the amount of menstrual blood is still within reasonable limits. Like uterine myomas, cervical myomas are not fused with the myometrial lining but are covered by thin connective tissue on the surface.The procedure of cervical myoma bas
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3

Seidel, Vera, Klaus Dieter Wernecke, Antonia Lukrezia Bellingkrodt, Robert Armbrust, and Matthias David. "Sonographic Monitoring of Growth of Uterine Myomas in Untreated Women and Respective Influence Factors." Geburtshilfe und Frauenheilkunde 83, no. 04 (2023): 446–52. http://dx.doi.org/10.1055/a-1996-2980.

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Abstract Research Question What are the growth patterns of uterine myomas in untreated premenopausal women? Which factors influence the growth rate of uterine myomas in premenopausal women? Method All premenopausal women who presented to the outpatient myoma consultation clinic between January 2005 and March 2022 at least twice were screened. Exclusion criteria were hormonal therapy, pregnancy, and postmenopausal status. Results A total of 189 patients were included in our study which focused on the respective largest uterine myoma of each woman. An ideal linear growth over time was assumed. M
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4

Meylani, Meylani, Esther Tamunu, Moudy Lombogia, and Yourisna Pasambo. "Health Education Using Lecuter And Leaflet Methods On Knowledge Of Women About Early Detection Of Utery Mioma." Media Kesehatan Politeknik Kesehatan Makassar 15, no. 1 (2020): 38. http://dx.doi.org/10.32382/medkes.v15i1.1359.

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Uterine myoma is a benign smooth muscle tumor of the uterus consisting of smooth muscle tissue cells, fibrous binding tissue and collagen located in the uterus. This benign neoplasm is most commonly experienced by women and its prevalence continues to increase by 70%. Myoma uteri can cause big problems in health. Meanwhile, the lack of health information regarding the etiology of myomas has not yet found effective therapy. The importance of health information about early detection of acquired myoma, can increase women's knowledge of the dangers of uterine myoma. The Purpose of this study was t
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5

Nasiadek, M., T. Krawczyk, and A. Sapota. "Tissue levels of cadmium and trace elements in patients with myoma and uterine cancer." Human & Experimental Toxicology 24, no. 12 (2005): 623–30. http://dx.doi.org/10.1191/0960327105ht575oa.

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The aim of this study was to investigate the cadmium (Cd), copper (Cu), zinc (Zn), iron (Fe), magnesium (Mg) and calcium (Ca) concentrations in uterine cancer and uterine myoma. Tissue levels of six elements in 15 uterine cancers and 28 uterine myomas were measured by atomic absorption spectrometry. The samples were collected from women aged 32-79 (uterine myomas, uterine cancer and non-lesion uterine tissues from the same women). The results showed that the tissue Cd concentration was significantly lower in myoma than in non-lesion tissue. In uterine cancer, however, it was statistically sign
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6

Haimovich, Sergio, Maite López-Yarto, Julio Urresta Ávila, Alejandro Saavedra Tascón, José L. Hernández, and Ramón Carreras Collado. "Office Hysteroscopic Laser Enucleation of Submucous Myomas without Mass Extraction: A Case Series Study." BioMed Research International 2015 (2015): 1–5. http://dx.doi.org/10.1155/2015/905204.

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Background and Objectives. A new two-step hysteroscopic myomectomy carried out in the office setting and without anesthesia was feasible for the excision of submucous myomas. The objective of this study was to assess whether removal of submucous myomas from the uterine cavity after hysteroscopic laser enucleation is necessary.Methods. Between June 2009 and April 2013, all outpatients with symptomatic myomatosis (bleeding, pelvic pain, and infertility) assessed ultrasonographically were eligible to participate in a prospective study. All patients underwent office hysteroscopic enucleation of su
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7

Cramer, Stewart F., Carol Marchetti, Joshua Freedman, and Aasim Padela. "Relationship of Myoma Cell Size and Menopausal Status in Small Uterine Leiomyomas." Archives of Pathology & Laboratory Medicine 124, no. 10 (2000): 1448–53. http://dx.doi.org/10.5858/2000-124-1448-romcsa.

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Abstract Context.—Although myomas shrink after menopause, the cellular mechanism for this phenomenon has received little attention. It was recently demonstrated that fibrous degeneration is significantly associated with postmenopausal status in both small and large myomas. Objective.—The purpose of the present study was to evaluate whether reduction in myoma cell size is also associated with postmenopausal status in small myomas. Design.—Tumor size and patient age have also been related to fibrous degeneration in small (<1 cm) myomas. Therefore, in the present study, 10 pairs of premeno
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8

Negmatullaeva, M., M. Hamdamova, and M. Hatamova. "CONSERVATIVE MYOMECTOMY IN WOMEN OF REPRODUCTIVE AGE." Doctor's Herald/ Доктор ахборотномаси /Вестник врача 93, no. 1 (2020): 61–63. http://dx.doi.org/10.38095/2181-466x-2020931-61-63.

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Uterine myoma is relatively rare in women aged 20-30, but disease risk increases significantly after the age of 35-40. The need to preserve fertility occurs in women of late reproductive age with uterine myoma also increases. Conservative myomectomy is considered to be the method of choice for surgical treatment of uterine myomas in reproductive period. The article describes types and techniques of conservative myomectomy.
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9

Cărbunaru, Ana, V. Herlea, M. Ionescu, and T. Dumitraşcu. "Extensive Left Iliac Veins and Inferior Vena Cava Thrombosis Revealing a Giant Uterine Myoma." Romanian Journal Of Internal Medicine 54, no. 1 (2016): 70–73. http://dx.doi.org/10.1515/rjim-2016-0009.

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A deep vein thrombosis was rarely associated with uterine myomas. Hereby, it is presented the case of a 40-year-old woman in which the clinical manifestation of the deep vein thrombosis revealed the further diagnosis of a large uterine myoma. The diagnosis, management and clinical outcome of the patient are emphasized and discussed. The management of a patient with a uterine myoma and deep vein thrombosis is challenging and implies a multidisciplinary team.
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10

Sena-Martins, Maurício, Cecilia Maria Roteli-Martins, Valdir Tadini, Gustavo Antonio de Souza, Nestor Kisilevzky, and Felipe Lazar Junior. "Uterine artery embolization for the treatment of symptomatic myomas in Brazilian women." Sao Paulo Medical Journal 121, no. 5 (2003): 185–90. http://dx.doi.org/10.1590/s1516-31802003000500002.

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CONTEXT: Uterine myomas are benign tumors that mostly occur in women of reproductive age at a frequency ranging from 20 to 25%. The symptoms are increased menstrual flow, pain and compressive signs. New treatments have been proposed and uterine artery embolization is one of them. OBJECTIVE: To evaluate the effects of treatment by embolization of the uterine artery, in women with symptomatic myomas. Uterine and dominant myoma volumes and the major symptoms were evaluated before treatment and 12 weeks later. TYPE OF STUDY: Open clinical trial. SETTING: A tertiary-care women's hospital. PARTICIPA
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11

Shibata, Naoki, Michihisa Shiro, Noriyoshi Oki, Takahiro Watanabe, Hitomi Futaki, and Shigeki Yoshida. "Spontaneous Parasitic Pedunculated Myoma Presenting the Absence of Uterine Smooth Muscle Cells in the Stalk — A Case Report." Gynecology and Minimally Invasive Therapy 13, no. 4 (2024): 265–68. http://dx.doi.org/10.4103/gmit.gmit_151_23.

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A few cases of spontaneous parasitic myoma have been reported. However, its cause remains unidentified. We report a case of spontaneous parasitic pedunculated subserosal myoma with pathological findings presenting with the absence of uterine smooth muscle cells in the stalk observed during robotic-assisted laparoscopic hysterectomy. A 51-year-old patient (G1P0) with no prior surgical history underwent a robotic-assisted laparoscopic hysterectomy. An approximately 3 cm-pedunculated subserosal myoma was found attached to the retroperitoneum. The stalk was sealed and separated and the myoma with
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12

Baktiar, Muhammad Priza, Khairunnisa binti Abd Rauf, and Khanisyah Erza Gumilar. "Simultaneous Myomectomy and Cesarean Section: A Dual Surgical Approach Pregnancy with enormous fibroid." Indonesian Journal of Perinatology 4, no. 2 (2023): 27–31. http://dx.doi.org/10.51559/inajperinatol.v4i2.35.

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Introduction: Myomectomy during cesarean section (CS) is a complex but increasingly common surgical approach used in cases of large uterine fibroids in pregnant patients. This report aims to evaluate the efficacy and safety of myomectomy in conjunction with CS for large uterine myoma. Case description: A retrospective study was conducted on two pregnant patients with large uterine myomas who underwent myomectomy during CS at a Hospital of Universitas Airlangga. Clinical data, myoma characteristics, and maternal and neonatal outcomes were evaluated. Myoma sizes were 15x15cm and 15x20cm, and bot
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13

Putra, Ida Bagus Agung Brahmananda Krisna, I. Komang Juni Arthawan, AA Gde Marvy Khrisna Pranamartha, et al. "SUCCESSFUL CONCEPTION AND FIRST PREGNANCY IN A 28-YEAR-OLD WOMAN WITH CERVICAL UTERINE MYOMA AND TOTAL PLACENTA PREVIA: A CASE REPORT." Journal of Advanced Research in Medical and Health Science (ISSN 2208-2425) 10, no. 10 (2024): 17–24. http://dx.doi.org/10.61841/te0naj48.

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Background: Placenta previa is a major pregnancy complication associated with life-threatening hemorrhage. Cervical Uterine Myomas, benign smooth muscle tumors, increase the risk of placenta previa by two to three times, contributing to adverse pregnancy outcomes such as infection, urinary retention, preterm labor, and bleeding. Understanding the interaction between Cervical Uterine Myomas and placenta previa is crucial for optimizing care in high-risk pregnancies and improving maternal and fetal outcomes. Case Description: A 28-year-old primigravida (G1P0A0) patient was diagnosed with a breec
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14

Dash, B. B., Anuradha Kapur, and Anupama Bahadur. "Successful laparoscopic assisted myomectomy of a gigantic 9.4 kg uterine parasitic myoma: a case report and review of literature." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 7, no. 3 (2018): 1265. http://dx.doi.org/10.18203/2320-1770.ijrcog20180935.

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Uterine leiomyomas are the most common benign tumours of the female pelvis affecting around 25-30% women of reproductive age. A case of successful laparoscopic assisted myomectomy in a giant uterine parasitic myoma is presented. A 42-year nulliparous morbidly obese lady presented with an Ultrasound diagnosis of a large uterine mass, detected during routine health check-up. MRI revealed a giant uterine pedunculated myoma of size 35 × 28 × 18 cm arising from the fundus and a 6 × 7 cm posterior wall myoma. After counselling the patient regarding surgical and anaesthesia risk, need of hysterectomy
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15

Tinelli, Andrea, Marina Vinciguerra, Antonio Malvasi, Mladen Andjić, Ivana Babović, and Radmila Sparić. "Uterine Fibroids and Diet." International Journal of Environmental Research and Public Health 18, no. 3 (2021): 1066. http://dx.doi.org/10.3390/ijerph18031066.

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Uterine myomas or fibroids are the most common benign female tumors of the reproductive organs, associated with significant morbidity and quality of life impairment. Several epidemiological risk factors for their occurrence have been identified so far, including nutrition and dietary habits. In this investigation, authors reviewed, as a narrative review, the data about diet and uterine myoma development in order to homogenize the current data. A PubMed search was conducted for the years 1990–2020, using a combination of keywords of interest for the selected topic. The authors searched the data
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16

Retnaningsih, Reny, and Zainal Alim. "Characteristics of uterine myoma patients at inpatient rooms of dr. Soepraon 2nd Grade Military Hospital, Malang." Majalah Obstetri & Ginekologi 28, no. 2 (2020): 89. http://dx.doi.org/10.20473/mog.v28i22020.89-92.

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Objectives: The aim of this study was to discover the characteristics of uterine myoma patients at the inpatient rooms of dr. Soepraon 2nd Grade Military Hospital, Malang.Case Report: Women reproductive system is prone to health problems, one of them is uterine myoma which being detected through pathology anatomy examination and shows an increasing prevalence (70%) nowadays. In Indonesia, the cases of uterine myoma reach 2,39 – 11,7%, placing second right after cervical cancer. The aim of this study was to discover the characteristics of uterine myoma patients at the inpatient rooms of dr. Soe
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17

Takeda, Satoru, Tsuyoshi Ota, Hiroshi Kaneda, Yasuhisa Terao, and Ryohei Kuwatsuru. "Abdominal Myomectomy for Huge Uterine Myomas with Intra-arterial Balloon Occlusion: Approach to Reduce Blood Loss." Surgery Journal 06, S 01 (2019): S11—S21. http://dx.doi.org/10.1055/s-0039-1693041.

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AbstractAbdominal myomectomy for a huge myomas, especially uterine cervical myoma, is difficult because of risks, such as intraoperative bleeding or injury to adjacent organs. Therefore, understanding of the positional relationships among a huge myoma, especially cervical or intraligamental myoma, and the vascular plexuses in the right and left cardinal ligaments is important for prevention of massive bleeding during myomectomy. While sufficiently performing preoperative assessment with pelvic examination, ultrasonography, magnetic resonance imaging (MRI), etc., surgeons should always keep in
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18

Kusuma, Anak Agung Ngurah Jaya. "Benefits and safety of myomectomy during cesarean section." Majalah Obstetri & Ginekologi 32, no. 1 (2024): 39–43. http://dx.doi.org/10.20473/mog.v32i12024.39-43.

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Uterine myoma is a tumor in the uterus that is generally benign. There are many types of uterine myomas. These tumors can grow on the outer wall of the uterus, on the uterine muscle, or it can also be on the inner wall of the uterus. The most frequent kind of uterine tumor is myoma. Uterine myoma mostly occurs in women over thirty years of age. Its prevalence ranges from 5.4% to 77%, with uterine fibroids accounting for up to 5% of pregnancies. The myomectomy procedure is an option for women who still want children but are concerned about the possibility of subsequent surgical intervention. Th
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19

Indryani, Indryani, Mustar Mustar, Sarina Ali, Susilawati Susilawati, and Ismawati Ismawati. "Relationship between menarche age and parity with the incidence of uterine myomas." Jurnal Ilmiah Kesehatan Sandi Husada 13, no. 2 (2024): 223–31. http://dx.doi.org/10.35816/jiskh.v13i2.1208.

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Background: Uterine myomas, or fibroids, are one of the most common benign tumors that occur in women of reproductive age, with a reasonably high prevalence worldwide. However, rarely, potentially malignant uterine myomas can cause a variety of health problems, including excessive menstruation, pelvic pain, fertility disorders, and pregnancy complications. Objective: This study aims to analyze the relationship between menarche age and parity with the incidence of uterine myoma. Methods: Types and design of research the plan used in this exploration is quantitative exploration with a case contr
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Tzvelev, Ju V., and A. B. Ilyin. "The diagnostics and treatment of dishormonal mammal hyperplasia in uterine myoma patients." Journal of obstetrics and women's diseases 48, no. 2 (1999): 30–34. http://dx.doi.org/10.17816/jowd88077.

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In gynecologic patients with internal genitalia diseases (endometriosis, uterine myoma) the frequency of mammal hyperplasia makes up to 60- 95%. The research aim was to study the effectiveness of conservative therapy with gestagens (norcolut, orgametril) application in benign hyperplastic mammal processes management in patients with uterine myomas. The effectiveness of gestagens application in patients with uterine myomas with coexisting dyshormonal mammal hyperplasia is proved.
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Anthonius Christopher Wisnu, Sony Sutrisno, Adrian Setiawan, and Monica Cherlady Anastasia. "Gambaran USG Leiomioma Uteri Pada Dewasa : LITERATURE REVIEW." DIAGNOSA: Jurnal Ilmu Kesehatan dan Keperawatan 1, no. 2 (2023): 01–24. http://dx.doi.org/10.59581/diagnosa-widyakarya.v1i2.115.

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Uterine myoma is one of the most common tumors found in premenopause. Symptoms that can arise vary, ranging from asymptomatic to symptoms that interfere with daily activities. The most common symptoms arise, namely pain and vaginal bleeding. Women who have, myoma diagnosed certainly emits risk factors. Risk factors that can aggravate, among them are heredity, obesity, hormonal contraception, nullipara, hypertension, primipara age <20 years, deficiency of vitamins D Risk Factors Risk of land can be able to be able That, as for effective modalities is used for supporting examinations of uteri
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22

KAYACIK GÜNDAY, Özlem. "Large cervical myoma originating from the uterine corpus." Journal of Experimental and Clinical Medicine 39, no. 3 (2022): 916–18. http://dx.doi.org/10.52142/omujecm.39.3.62.

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This case report aimed to present a case of large cervical myoma that obliterated the ureterovesical area and filled the entire cervix. A 33-year-old patient had a tumoral lesion of approximately 80x60 mm, compatible with myoma, that filled the cervical cavity. On vaginal examination, a barrel- shaped, immobile and large cervix was palpated. A preoperative bilateral double J catheter was applied to the patient. While the uterine cervix was barrel-shaped due to myoma and was palpable from Douglas, it was firmly fixed anteriorly to the bladder and corpus. During bladder dissection, approximately
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23

Timchenko, Marina A., Tatiana A. Kuznetsova, Tatyana I. Morozova, and Mariya G. Nikolaeva. "Predicting recurrence of uterine myoma after carrying out a selective uterine arteries embolization." Gynecology 24, no. 2 (2022): 95–100. http://dx.doi.org/10.26442/20795696.2022.2.201279.

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Aim. To establish clinic and anamnestic predictors for recurrence of uterine myomas growth after carrying out a selective uterine arteries embolization (s-UAE).
 Materials and methods. The one-center longitudinal retrospective cohort study including 366 women with symptomatic uterine myoma, after carrying out s-UAE at 20132017. The Control group 315 patients after s-UAE with absolute reduction of blood-circulation and strong remission for 3 years. The main group 51 cases of restoration of clinical symptoms and blood-groove after ultrasonography registered absolute reduction and knocking o
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24

Veropotvelyan, N. P., L. V. Gazarova, Yu S. Pogulyay, et al. "Prenatal diagnosis of Down syndrome in pregnant woman with giant uterine myoma and hereditary thrombophilia." HEALTH OF WOMAN, no. 3(129) (April 30, 2018): 24–29. http://dx.doi.org/10.15574/hw.2018.129.24.

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The article describes the case of prenatal diagnosis of Down’s syndrome in a 17 weeks of gestation fetus in a 39-year-old pregnant woman with the first detected giant necrotic uterine myoma and a tendency to hypercoagulable against the background of the heterozygous carriage of the Leyden mutation. At 20 weeks of gestation, due to the inability to proliferate through the natural birth canal, extirpation of the uterus with the fetus (without appendages) was carried out along the Rhine-Poros. At autopsy the diagnosis was confirmed. Timely medical and prophylactic measures allowed to avoid the de
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Zhu, Jihe, Blagica Arsovska, Kristina Kozovska, and Svetlana Jovevska. "Acupuncture and herbal treatment for human papillomavirus (HPV) and uterine myoma." World Journal of Advanced Research and Reviews 6, no. 2 (2020): 166–69. https://doi.org/10.5281/zenodo.4313166.

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Human papillomavirus (HPV) is the most common sexually transmitted infection globally. Almost all cervical cancers are due to HPV with two types, HPV16 and HPV18, which account for 70% of cases. Myomas are benign growths in different parts and places of the uterus. In this research is presented a case of 32 year old woman diagnosed with uterine myoma and HPV type 16. The myoma was found in September, 2018 and the HPV infection in January, 2020, two years later after the myoma was treated. The myoma was treated with 10 acupuncture treatments, Cordiceps synensis tea capsules 1.5 grams per day an
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Gunnala, Vinay, Robert Setton, Nigel Pereira, and Jian Qun Huang. "Robot-Assisted Myomectomy for Large Uterine Myomas: A Single Center Experience." Minimally Invasive Surgery 2016 (2016): 1–5. http://dx.doi.org/10.1155/2016/4905292.

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Objective.To determine if robot-assisted myomectomy (RAM) is feasible for women with large uterine myomas.Methods.Retrospective review of one gynecologic surgeon’s RAM cases between May 2010 and July 2013. Large uterine myomas, defined as the largest myoma ≥9 cm by preoperative magnetic resonance imaging, was age- and time-matched to controls with the largest myoma <9 cm. Primary surgical outcomes compared were operative time and estimated blood loss (EBL).Results.207 patients were included: 66 (32%) patients were in the ≥9 cm group, while 141 (68%) patients were in the <9 cm group. Ther
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Soloviev, A. "Uterine fibroids as an obstacle to childbirth." Journal of obstetrics and women's diseases 6, no. 6 (2020): 618. http://dx.doi.org/10.17816/jowd66618.

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With the frequency of uterine myomas, they are rarely obstacles to childbirth, since with large myomas most of the conception does not occur, with small ones, there are usually miscarriages. Low-sitting submucosal and intermuscular myomas create mechanical obstacles for childbirth, higher located ones cause irregularities of attempts, delay in child's place and bleeding, while a small subperitoneal, sitting on a thin leg of myoma, does not represent obstacles for childbirth.
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Wulandari, Ade Dinda, Putu Nita Cahyawati, and Kadek Agus Kurniawan. "HUBUNGAN USIA DAN PARITAS DENGAN KEJADIAN MIOMA UTERI DI RSUD WANGAYA DENPASAR TAHUN 2016-2017." Bali Health Journal 5, no. 2 (2021): 104–10. https://doi.org/10.34063/bhj.v5i2.209.

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Background: Uterine myoma is a female reproductive health problem that has a significant effect on morbidity and quality of life. The incidence rate of uterine myoma in Indonesia is 2.39%-11.7%. The second-highest case after cervical cancer. The risk factors for uterine myoma are not fully known. Several studies reported the incidence of uterine myoma related to age and parity, but other studies reported different results. Purpose: This study aims to determine the relationship between age and parity with the incidence of uterine myoma at RSUD Wangaya Denpasar. Methods: This study was an observ
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Nawangsari, Harnanik, Liliek Pratiwi, and Yane Liswanti. "Pengetahuan dengan Sikap dalam Pencegahan Mioma Uteri pada Mahasiswa." Malahayati Nursing Journal 5, no. 6 (2023): 1808–12. http://dx.doi.org/10.33024/mnj.v5i6.8855.

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ABSTRACT In Indonesia, uterine myoma affects one in three women. Uterine myoma is a disease that grows in the female reproductive organs. Along with developments in the medical field, many young women do not take care of their reproductive health. This causes the impact of uterine myoma patients having to undergo surgery, then if it is at a serious stage, removal of the uterus or histerektomi. The impact of removing the uterus is early menopause, besides that women feel pain when lifting weights. Uterine myomas are not a very serious problem because they are still classified as benign tumors,
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30

Markowska, Anna, Paweł Kurzawa, Wiesława Bednarek, et al. "Immunohistochemical Expression of Vitamin D Receptor in Uterine Fibroids." Nutrients 14, no. 16 (2022): 3371. http://dx.doi.org/10.3390/nu14163371.

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One of the many factors involved in the development of uterine fibroids is vitamin D deficiency. One aspect of this deficiency is decreased serum concentration of calcidiol-25(OH)D, a metabolite of D3 vitamin. The active form of vitamin D3, which arises after numerous enzymatic reactions, is calcitriol-1,25(OH)2D3; this compound is transported to various body tissues. Vitamin D possesses extra-genomic effects due to its influence on various signaling pathways, i.e., through activating tyrosine kinases and by genomic effects via binding to a specific nuclear receptor, vitamin D receptor (VDR).
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Plewka, Danuta, Jacek Marczyński, Michał Morek, Edyta Bogunia, and Andrzej Plewka. "Receptors of Hypothalamic-Pituitary-Ovarian-Axis Hormone in Uterine Myomas." BioMed Research International 2014 (2014): 1–13. http://dx.doi.org/10.1155/2014/521313.

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In this study the expression of GnRH, FSH, LH, ER-α, ER-β, and PR receptors was examined in uterine myomas of women in reproductive and perimenopausal age. In cases of GnRH and tropic hormones a membranous and cytoplasmic immunohistochemical reaction was detected, in cases of ER-αand PR the reaction was located in cell nucleus, and in the case of ER-βit manifested also a cytoplasmic location. In some of the examined cases the expression was detected in endometrium, myocytes, and endothelium of blood vessels, in uterine glands and myoma cells. In myometrium the level of GnRH and LH receptors in
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32

Courtoy, Guillaume E., Patrick Henriet, Etienne Marbaix, et al. "Matrix Metalloproteinase Activity Correlates With Uterine Myoma Volume Reduction After Ulipristal Acetate Treatment." Journal of Clinical Endocrinology & Metabolism 103, no. 4 (2018): 1566–73. http://dx.doi.org/10.1210/jc.2017-02295.

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Abstract Context Ulipristal acetate (UPA), a selective progesterone receptor modulator, clinically reduces uterine myoma size in 80% of cases. However, the molecular mechanism of action is still poorly understood, as is the reason why 20% of myomas do not respond to treatment. Objective To elucidate whether matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) are associated with myoma volume shrinkage after UPA therapy. Design Prospective study. Setting Academic research unit of a university hospital. Patients Uterine biopsies were obtained from 59 patients with
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33

Kim, Ji Young, and Sung Yob Kim. "The obstetric outcomes and treatment of myoma in pregnancy." Journal of Medicine and Life Science 6, no. 1 (2007): 21–28. http://dx.doi.org/10.22730/jmls.2008.6.1.21.

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Uterine myomas are the most common neoplasm of uterus, occurring in at least 20~25% of all reproductive age women, and 1%~3.9% of pregnant women.Uterine myomas are observed in pregnancy more frequently now than in the past, with the increasing age of the obstetric population and the widespread use of sonography. Although most myoma remain asymptomatic, some of them cause various comlication during pregnancy, labor, and delivery. and these complications related with size, number, position, location, relationship to the placenta of myoma.The traditional management of myoma in pregnancy is conser
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de la Fuente, Elena, María Dolores Borrás, Miriam Rubio, and Nuria Abril. "Ulipristal Acetate in Myomectomy Optimization in an Infertile Patient with Giant Myomas." Case Reports in Medicine 2016 (2016): 1–3. http://dx.doi.org/10.1155/2016/5135780.

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The use of ulipristal acetate (UPA) has been recently introduced in the treatment of uterine leiomyomas. This drug has proven useful to control menometrorrhagia and to reduce myoma size. In the case presented here, we show the benefits of UPA treatment in facilitating surgical removal of giant myomas in an infertile patient. In addition to myoma reduction and a better control of preoperative bleeding, the treatment with UPA reduced the duration and complexity of the surgery, as well as the area of uterine wall involved and the resulting scar. No side effects were observed and the patient becam
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Pattinasarany, Camelia Gracia, Novy Riyanti, Halidah Rahawarin, Arlen Resnawaldi, Juliet Sinanu, and Merlin M. Maelissa. "KARAKTERISTIK STATUS OBSTETRI PADA PASIEN MIOMA UTERI DI RSUD DR. M. HAULUSSY AMBON TAHUN 2018-2021." PAMERI: Pattimura Medical Review 5, no. 1 (2023): 31–39. http://dx.doi.org/10.30598/pamerivol5issue1page31-39.

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Uterine myoma or uterine leiomyoma or fibroid are benign tumors of the smooth muscle of the uterus, which occur in 20-25% of women of reproductive age. One of the things that can stimulate the occurrence of uterine myoma is estrogen, that is why uterine myoma cannot be identified before puberty and it could shrink or even disappear when entering menopause. Not all uterine myoma have symptoms, the symptoms will appear according to the location where the uterine myoma is sited. Complications can occur depending on the location, which can interfere with the pregnancy until postpartum. This study
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Yokoe, Takuya, Hisato Fukuda, Yuri Noda, and Masato Kita. "Acute abdomen caused by internodular bleeding from a multiple myoma pseudocapsule in a postmenopausal woman." BMJ Case Reports 16, no. 10 (2023): e255230. http://dx.doi.org/10.1136/bcr-2023-255230.

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A woman in her 50s presented with lower abdominal pain. She had a diagnosis of multiple uterine myomas 3 years earlier, followed by menopause. CT showed a pelvic mass of 19.5×9.4×10.2 cm in size, containing a haemorrhagic component. It was assumed that the tumour was the previously diagnosed myoma, and that it had increased to 150% of the size noted 3 years ago. An emergent hysterectomy was performed, and the pathological diagnosis was a uterine leiomyoma, with no components suggestive of sarcoma or degeneration. We witnessed a rare case of acute abdomen caused by internodular bleeding of mult
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37

Timofeev, A. I. "Fibroids of the uterus with intravascular growth." Kazan medical journal 17, no. 2 (2021): 219–23. http://dx.doi.org/10.17816/kazmj79461.

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As you know, in the controversial issue of the histogenesis of uterine fibroids, the so-called. vascular theory occupies a fairly prominent place. I am among my defenders of such prominent representatives of natka as Borst, Orth, Lubagsch, Gottschalk, etc. Despite the high probability of such a histogenesis of uterine myomas, it should be noted that the growth of tumors into the lumen of the vessels is extremely rare, and only a few cases of this kind are described in the literature. Various authors, describing tumors spreading in their growth along the preexisting cavities, give them differen
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Buralkina, N. A., G. A. Vlasov, A. V. Veredchenko, et al. "Clinical observation: giant uterine myoma. The tactic of surgical treatment and postoperative management." Medical Council, no. 13 (September 25, 2018): 22–26. http://dx.doi.org/10.21518/2079-701x-2018-13-22-26.

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The article deals with the clinical case of a patient with giant uterine myoma. It presents the features of surgical intervention and postoperative management of the patient. In the publication, the authors discuss the issues concerning the scope of the surgery in patients with large and giant uterine myomas and prognosis of reproductive outcomes in this cohort of women.
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Cabezas, Nieves, Ana López-Picazo, Patricia Diaz, et al. "How Frequently Benign Uterine Myomas Appear Suspicious for Sarcoma as Assessed by Transvaginal Ultrasound?" Diagnostics 13, no. 3 (2023): 501. http://dx.doi.org/10.3390/diagnostics13030501.

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Background: Uterine myomas may resemble uterine sarcomas in some cases. However, the rate of benign myomas appearing as sarcomas at an ultrasound examination is not known. The objective of this study is to determine the percentage of benign myomas that appear suspicious for uterine sarcoma on ultrasound examination. This is a prospective observational multicenter study (June 2019–December 2021) comprising a consecutive series of patients with histologically proven uterine myoma after hysterectomy or myomectomy who underwent transvaginal and/or transabdominal ultrasound prior to surgery. All ul
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40

Erlindawati, Erlindawati. "FAKTOR-FAKTOR YANG BERHUBUNGAN DENGAN KEJADIAN MIOMA UTERI DI RUMAH SAKIT KOTA BENGKULU TAHUN 2012." JURNAL MEDIA KESEHATAN 5, no. 2 (2018): 154–62. http://dx.doi.org/10.33088/jmk.v5i2.191.

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The uterine myoma is the major maligna problem in the woman reproduction that causing the clinical syndrome especially bleeding, excessive menstruation, infertility, the repeatedly abortus, and pain due to the mass pressure. The problem of the research is the increasing numbers of the myoma case. The aim of the research is to reveal the relation between the uterine myoma and the age of mother, parity, menarche age, obesity, and the hormonal contraception in the hospital of Bengkulu. This research is a kind of analytical survey. The designed used in this research is case. The population is all
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41

Erlindawati, Erlindawati. "FAKTOR-FAKTOR YANG BERHUBUNGAN DENGAN KEJADIAN MIOMA UTERI DI RUMAH SAKIT KOTA BENGKULU TAHUN 2012." JURNAL MEDIA KESEHATAN 5, no. 2 (2018): 154–62. http://dx.doi.org/10.33088/jmk.v5i2.191.

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The uterine myoma is the major maligna problem in the woman reproduction that causing the clinical syndrome especially bleeding, excessive menstruation, infertility, the repeatedly abortus, and pain due to the mass pressure. The problem of the research is the increasing numbers of the myoma case. The aim of the research is to reveal the relation between the uterine myoma and the age of mother, parity, menarche age, obesity, and the hormonal contraception in the hospital of Bengkulu. This research is a kind of analytical survey. The designed used in this research is case. The population is all
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42

Laning, Ivani, Imelda Manurung, and Amelia Sir. "Faktor Risiko yang Berhubungan dengan Kejadian Penyakit Mioma Uteri." Lontar : Journal of Community Health 1, no. 3 (2019): 95–102. http://dx.doi.org/10.35508/ljch.v1i3.2174.

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Uterine myoma is a benign tumor of the uterine muscle, accompanied by connective tissue so that it can be in solid form, because the connective tissue is dominant and soft. The incidence of uterine myoma in Indonesia at 2013 showed found 2,39 % - 11,70% in all gynecological cases suffererswhich generally occur in women age > 35 years. This study aims to determine the risk factors associated with the incidence of uterine myoma in patients at RSUD Prof. Dr. W.Z. JOHANNES kupang in 2019. This type of research is observational analytic with a case control design. The number of samples were 41 r
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Ricci, Giuseppe, Federica Scrimin, Andrea Sartore, et al. "Characteristics of Submucous Myomas and the Risk of Anemia." Medicina 58, no. 11 (2022): 1652. http://dx.doi.org/10.3390/medicina58111652.

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Background and Objectives: Uterine fibroids still represent the most common indication for hysterectomy for benign pathologies. In the United States, more than 479,000 hysterectomies are performed annually, 46.6% for myomas and 47.7% in women aged from 18 to 44 years. By applying appropriateness criteria to this procedure, it has been estimated that overuse ranges from 16 to 70%. One of the main reasons that induce patients and gynecologists to consider hysterectomy is represented by severe anemia. Materials and Methods: This is a retrospective cohort study of 202 patients with uterine fibroid
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Dwistayani, Ni Made Youthma, and Kadek Agus Wijaya. "MANAGEMENT MULTIPLE UTERINE MYOMA IN PREGNANCY: A CASE REPORT." Majalah Ilmiah METHODA 12, no. 2 (2022): 78–83. http://dx.doi.org/10.46880/methoda.vol12no2.pp78-83.

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Uterine myoma is a benign tumor originating from the smooth muscle of the uterus. In general, uterine myomas are asymptomatic and are found incidentally during ultrasound examination of pregnancy. We report that a 39-year-old woman with GIIP1001 admitted that she was 40 weeks pregnant and came with complaints of intermittent abdominal pain that started at 04.00 in the morning, getting worse 2 hours before MRS. Complaints accompanied by the discharge of blood mucus through the vagina. The patient was married 2 times and the distance between the first child and the second is 19 years. The patien
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Tregub, V. V., V. A. Kondratyuk, I. V. Altman, O. K. Tarasiuk, and Yu K. Sikalo. "Clinical experience of using the technique of uterine artery embolization in the treatment of submucous uterine fibroids in the Vidar Medical Center, Vinnytsia (2008–2022)." Reproductive health of woman, no. 1 (March 1, 2024): 53–61. http://dx.doi.org/10.30841/2708-8731.1.2024.301599.

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Myoma of the uterus is a benign neoplasm. The technique of uterine artery embolization (UAE) is used to treat uterine fibroids and is highly effective. The principle of embolization is based on the fact that all blood vessels that supply the uterus end in the endometrium.During UAE small parts are injected – emboli, which are spread along these vessels with the blood flow. In the vessels of the myoma the emboli cannot pass through the capsule of the myoma, so they block the vessels that supply it with blood. This leads to the cessation of blood supply to myomatous nodes, and subsequently there
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Н., В. Косей. "Uterine myoma: еtiology and morphogenesis". Reproductive Endocrinology, № 40 (30 квітня 2018): 23–32. https://doi.org/10.18370/2309-4117.2018.40.23-32.

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Uterine myoma is the most common tumor of female genital organs. Despite the significant achievements of modern science and the many studies devoted to this benign tumor, its initiating factors remain unknown. To investigate etiological factors and features of the morphogenesis of uterine leiomyoma for further development of the tactics of its prevention and treatment, the literature data and the results of our original studies, including results of submicroscopic studies, were analyzed. It was revealed that among important etiological factors are African-American ethnic group, nutrition rich
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47

Kudrina, Elena A., and Dmitry V. Baburin. "Uterine myoma: modem aspects of pathogenesis and treatment (clinical lecture)." V.F.Snegirev Archives of Obstetrics and Gynecology 3, no. 1 (2016): 4–10. http://dx.doi.org/10.18821/2313-8726-2016-3-1-4-10.

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In the clinical lecture there are considered modern aspects of pathogenesis, risk factors, diagnosis and treatment of uterine myoma - one of the most common diseases in females of reproductive and menopausal age. Among the major pathogenetic mechanisms of the development of uterine myoma the special attention has been paid to gene and chromosomal aberrations, disturbances of carbohydrate and fat metabolism, chronic inflammatory responses. There was emphasized the attention to modern organ-saving methods of the management of uterine myoma with taking in account the clinical course of the diseas
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Senturk, Mehmet Baki, Mehmet Şükrü Budak, Yusuf Çakmak, and Kasim Turan. "Is myomectomy safe during cesarean section in large myomas?" Medical Science and Discovery 2, no. 5 (2019): 292–96. https://doi.org/10.36472/msd.v2i5.120.

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Objective: The rate of cesarean section, gravida and pregnancy age have been gradually increasing. Thus the rate of myoma have increased during cesarean. But it may difficult to make decision aboıut myomectomy during cesarean especially large myomas because of complications. Therefore, several obstetricians do not recommend cesarean myomectomy, except in cases of small and pedunculated uterine fibroids that do not result in complications. The aim of this study to evaluate safety of myomectomy during emergency cesarean section in large myomas. Material and Methods: We examined retrospectively t
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Adenin, Ichwanul, Muhammad Oki Prabudi, Hilma Putri Lubis, and Edward Muljadi. "Successful Application of Manual Hand Morcellation Technique in Giant Leiomyoma: A Case Report." Open Access Macedonian Journal of Medical Sciences 10, no. C (2022): 176–78. http://dx.doi.org/10.3889/oamjms.2022.8895.

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Introduction: Uterine leiomyoma is the most common benign neoplasm of the female reproductive tract. However, he use of the laparoscopy approach for giant myomas is still controversial and rarely performed. Only few cases have been published in the literature. Retrieval of giant myoma in laparoscopy is difficult and still challenging even by a power morcellator.
 Case presentation: A 39 years old para 3 woman was referred to the gynaecology department with abdominal swelling during the previous 3 years. No family history, past medical and gynaecology history disease was reported. A physic
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Zaitseva, Е. G., А. G. Marenin, and V. К. Biteev. "The experience of combined treatment of uterine submucous myoma." Journal of obstetrics and women's diseases 54, no. 5S (2005): 92. http://dx.doi.org/10.17816/jowd87578.

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Introductions. With the advent of new technologies in medicine, with ultrasound procedures being widely spread and available to every woman the diagnosed cases of uterine pathology today are about 40%. Submucous uterine myoma is diagnosed in every 3d-4th cases of diagnosed uterine myoma.
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