Relevant bibliographies by topics / Vaccination – Genetic aspects

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Academic literature on the topic 'Vaccination – Genetic aspects'

Author: Grafiati
Published: 4 June 2021
Last updated: 7 February 2022

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Journal articles on the topic "Vaccination – Genetic aspects"

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Bondarev, V. P., V. A. Shevtsov, I. N. Indikova, E. E. Evreinova, and D. V. Gorenkov. "Rotavirus Epidemiology and Vaccination Tactics." BIOpreparations. Prevention, Diagnosis, Treatment 19, no. 2 (June 16, 2019): 81–87. http://dx.doi.org/10.30895/2221-996x-2019-19-2-81-87.

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Rotavirus infection is a widespread cause of severe gastroenteritis in children in low-income countries. Specific prophylaxis in young children has become the most important means of combating severe rotavirus gastroenteritis. The review presents current data on the molecular biology and genetic diversity of rotaviruses, interaction of viral proteins with host cell receptors, molecular aspects of infectivity and pathogenesis of rotavirus infection, and the development of immunity. It addresses a new approach to the epidemiology of rotavirus infection which regards it as a manageable infection,
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PIKUŁA, ANNA, and KRZYSZTOF ŚMIETANKA. "Selected aspects of infectious bursal disease – the current state of knowledge." Medycyna Weterynaryjna 74, no. 10 (2023): 6138–2023. http://dx.doi.org/10.21521/mw.6138.

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Infectious bursal disease (IBD) is a highly infectious and contagious immunosuppressive viral disease of chickens with a worldwide economic significance to the poultry industry. Over fifty years have passed since the first confirmed occurrence of the disease, and the virus has spread all over world and evolved into multiple genetic, antigenic and pathotypic variants, becoming a serious threat to the poultry industry. The primary tool in IBD eradication is the maintenance of strict biosecurity in poultry farms and implementation of vaccination programmes which should take into account the curre
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Teale, Alan. "Biotechnology: a key element in the CGIAR's livestock research programme." Outlook on Agriculture 26, no. 4 (December 1997): 217–25. http://dx.doi.org/10.1177/003072709702600403.

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The unique potential of biotechnology to provide new solutions to old problems constraining the contribution of livestock to farming systems in the developing world is emphasized in this paper. An overview of biotechnological aspects of livestock research within the CGIAR, including a description of the research approaches being adopted at the International Livestock Research Institute, is provided. The products of the research are then identified, and their potential applications in disease diagnosis and vaccination, as well as in the fields of animal breeding and genetic improvement, are des
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HELGESSON, GERT, and STEFAN ERIKSSON. "Four Themes in Recent Swedish Bioethics Debates." Cambridge Quarterly of Healthcare Ethics 20, no. 3 (May 20, 2011): 409–17. http://dx.doi.org/10.1017/s0963180111000090.

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A wide variety of bioethical themes have recently been debated and researched in Sweden, including genetic screening, HPV vaccination strategies, end-of-life care, injustices and priority setting in healthcare, dual-use research, and the never-ending story of scientific fraud. Also, there are some new events related to Swedish biobanking that might be of general interest. Here we will concentrate on four themes: end-of-life care, dual-use research, scientific fraud, and biobanking.
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Mehra, Narinder K., and Gurvinder Kaur. "MHC-based vaccination approaches: progress and perspectives." Expert Reviews in Molecular Medicine 5, no. 7 (February 24, 2003): 1–17. http://dx.doi.org/10.1017/s1462399403005957.

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The major histocompatibility complex (MHC) harbours genes whose primary function in regulating immune responsiveness to infection is to present foreign antigens to cytotoxic T lymphocytes (CTLs) and T helper cells. In the case of infection by human immunodeficiency virus (HIV), defining the optimal HIV epitopes that are recognised by CTLs is important for vaccine design, and this in turn will depend on the characteristics of the predominant infecting virus. Moreover, the particular MHC human leukocyte antigens (HLAs) expressed by a geographical population is important since these are likely to
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Tusup, Marina, Lars E. French, Mara De Matos, David Gatfield, Thomas Kundig, and Steve Pascolo. "Design of in vitro Transcribed mRNA Vectors for Research and Therapy." CHIMIA International Journal for Chemistry 73, no. 5 (May 29, 2019): 391–94. http://dx.doi.org/10.2533/chimia.2019.391.

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The use of in vitro transcribed messenger RNA (ivt mRNA) for vaccination, gene therapy and cell reprograming has become increasingly popular in research and medicine. This method can be used in vitro (transfected in cells) or administered naked or formulated (lipoplexes, polyplexes, and lipopolyplexes that deliver the RNA to specific organs, such as immune structures, the lung or liver) and is designed to be an immunostimulatory or immunosilent agent. This vector contains several functional regions (Cap, 5' untranslated region, open reading frame, 3' untranslated region and poly-A tail) that c
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Ambinder, Alexander J., Pareen J. Shenoy, Neha Malik, Alison Maggioncalda, Loretta J. Nastoupil, and Christopher R. Flowers. "Exploring Risk Factors for Follicular Lymphoma." Advances in Hematology 2012 (2012): 1–13. http://dx.doi.org/10.1155/2012/626035.

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Follicular lymphoma (FL) is an indolent malignancy of germinal center B cells with varied incidence across racial groups and geographic regions. Improvements in the classification of non-Hodgkin lymphoma subtypes provide an opportunity to explore associations between environmental exposures and FL incidence. Our paper found that aspects of Western lifestyle including sedentary lifestyle, obesity, and diets high in meat and milk are associated with an increased risk of FL. Diets rich in fruits and vegetables, polyunsaturated fatty acids, vitamin D, and certain antioxidants are inversely associa
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Eckmann, Lars, and Frances D. Gillin. "Microbes and Microbial Toxins: Paradigms for Microbial- Mucosal Interactions I. Pathophysiological aspects of enteric infections with the lumen-dwelling protozoan pathogenGiardia lamblia." American Journal of Physiology-Gastrointestinal and Liver Physiology 280, no. 1 (January 1, 2001): G1—G6. http://dx.doi.org/10.1152/ajpgi.2001.280.1.g1.

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Giardia lamblia is one of the most important causes of waterborne diarrheal disease worldwide, and giardiasis is the most common protozoan infection of the human small intestine. Symptomatic infection is characterized by diarrhea, abdominal pain, and malabsorption, leading to malnutrition and weight loss, particularly in children. The pathogen resides strictly in the lumen of the small intestine, and infection is typically not accompanied by significant mucosal inflammation. Clinical and experimental studies indicate that B cell-dependent host defenses, particularly IgA, are important for cont
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Eckert, Johannes, and Peter Deplazes. "Biological, Epidemiological, and Clinical Aspects of Echinococcosis, a Zoonosis of Increasing Concern." Clinical Microbiology Reviews 17, no. 1 (January 2004): 107–35. http://dx.doi.org/10.1128/cmr.17.1.107-135.2004.

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SUMMARY Echinococcosis in humans is a zoonotic infection caused by larval stages (metacestodes) of cestode species of the genus Echinococcus. Cystic echinococcosis (CE) is caused by Echinococcus granulosus, alveolar echinococcosis (AE) is caused by E. multilocularis, and polycystic forms are caused by either E. vogeli or E. oligarthrus. In untreated cases, AE has a high mortality rate. Although control is essentially feasible, CE remains a considerable health problem in many regions of the northern and southern hemispheres. AE is restricted to the northern hemisphere regions of North America a
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Sang, Helen. "DISEASE RESISTANCE AND OTHER APPLICATIONS OF TRANSGENESIS IN THE CHICKEN." Reproduction, Fertility and Development 25, no. 1 (2013): 320. http://dx.doi.org/10.1071/rdv25n1ab345.

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Genetic modification of the chicken in terms of gene addition is now robust and efficient. Transgenes can be introduced by injection of lentiviral vectors into chick embryos or by transfection of transposon vectors into embryos or primordial germ cells in vitro. Lentiviral vectors are limited in the size of transgene they can incorporate but we have generated several different transgenic lines using HIV-derived vectors and have observed high levels of transgene expression and tissue-specific expression using regulatory sequences from several genes. M. McGrew (The Roslin Institute) has establis
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Dissertations / Theses on the topic "Vaccination – Genetic aspects"

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Baynam, Gareth. "Genetic influences on vaccine response in children." University of Western Australia. School of Paediatrics and Child Health, 2008. http://theses.library.uwa.edu.au/adt-WU2008.0259.

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Vaccination is one of the most efficacious public health interventions1 and has been increasingly used to combat non-infectious diseases. Mechanisms underlying vaccine responses overlap with those regulating immune responses in health and disease. Therefore, an understanding of mechanisms underpinning these responses will have broad implications. Variation in immune response genes contributes to impaired vaccine responses2-4. Understanding the contribution of genetic variants to vaccine responses is likely to be particularly important in early life given the generalized functional immaturity o
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Hollister, Kristin N. "Elucidating the role of BCL6 in helper T cell activation, proliferation, and differentiation." Thesis, 2014. http://hdl.handle.net/1805/5930.

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Indiana University-Purdue University Indianapolis (IUPUI)<br>The transcriptional repressor BCL6 has been shown to be essential for the differentiation of germinal center (GC) B cells and follicular T helper (TFH) cells. The interaction of TFH and GC B cells is necessary for the development of high affinity antibodies specific for an invading pathogen. Germline BCL6-deficient mouse models limit our ability to study BCL6 function in T cells due to the strong inflammatory responses seen in these mice. To overcome this, our lab has developed a new BCL6 conditional knockout (cKO) mouse using
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Books on the topic "Vaccination – Genetic aspects"

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Kampourakis, Kostas, and Kevin McCain. Uncertainty. Oxford University Press, 2019. http://dx.doi.org/10.1093/oso/9780190871666.001.0001.

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Scientific knowledge is the most solid and robust kind of knowledge that humans have because of its inherent self-correcting character. Nevertheless, anti-evolutionists, climate denialists, and anti-vaxxers, among others, question some of the best-established scientific findings, making claims unsupported by empirical evidence. A common aspect of these claims is reference to the uncertainties of science concerning evolution, climate change, vaccination, and so on. This is inaccurate: whereas the broad picture is clear, there will always exist uncertainties about the details of the respective p
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Journal articles
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