Relevant bibliographies by topics / Vaginal immunization

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Book chapters
  4. Conference papers
  5. Reports

Academic literature on the topic 'Vaginal immunization'

Author: Grafiati
Published: 14 March 2023
Last updated: 31 July 2025

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Journal articles on the topic "Vaginal immunization"

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Parr, Earl L., and Margaret B. Parr. "Immunoglobulin G, Plasma Cells, and Lymphocytes in the Murine Vagina after Vaginal or Parenteral Immunization with Attenuated Herpes Simplex Virus Type 2." Journal of Virology 72, no. 6 (1998): 5137–45. http://dx.doi.org/10.1128/jvi.72.6.5137-5145.1998.

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ABSTRACT This investigation evaluated immunity to vaginal herpes simplex virus type 2 (HSV-2) infection after local or parenteral immunization with attenuated HSV-2. Vaginal immunization induced sterilizing immunity against challenge with a high dose of wild-type virus, whereas parenteral immunizations protected against neurologic disease but did not entirely prevent infection of the vagina. Vaginal immunization caused 86- and 31-fold increases in the numbers of immunoglobulin G (IgG) plasma cells in the vagina at 6 weeks and 10 months after immunization, whereas parenteral immunizations did n
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Johansson, Eva-Liz, Carola Rask, Margareta Fredriksson, Kristina Eriksson, Cecil Czerkinsky, and Jan Holmgren. "Antibodies and Antibody-Secreting Cells in the Female Genital Tract after Vaginal or Intranasal Immunization with Cholera Toxin B Subunit or Conjugates." Infection and Immunity 66, no. 2 (1998): 514–20. http://dx.doi.org/10.1128/iai.66.2.514-520.1998.

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ABSTRACT We studied the antibody response including antibody-secreting cells (ASC) in the female genital tract of mice after mucosal immunizations with the recombinant B subunit of cholera toxin (rCTB) perorally, intraperitoneally, vaginally, and intranasally (i.n.). The strongest genital antibody responses as measured with a novel perfusion-extraction method were induced after vaginal and i.n. immunizations, and these routes also gave rise to specific immunoglobulin A (IgA) and IgG ASC in the genital mucosa. Specific ASC in the iliac lymph nodes, which drain the female genital tract, were see
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Wira, C. R., and C. P. Sandoe. "Specific IgA and IgG antibodies in the secretions of the female reproductive tract: effects of immunization and estradiol on expression of this response in vivo." Journal of Immunology 138, no. 12 (1987): 4159–64. http://dx.doi.org/10.4049/jimmunol.138.12.4159.

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Abstract Uterine and vaginal secretions collected from intact adult female rats were analyzed to determine whether immunization at sites distal to the reproductive tract had any effect on the presence of specific IgA and IgG antibodies in genital tract secretions. Peyer's patch and i.p. immunization and boost with sheep red blood cells (SRBC) stimulated the appearance of specific IgA antibodies in uterine and vaginal secretions of uterine-ligated animals. IgG antibodies were also induced in uterine but not in vaginal secretions. In contrast, subcutaneous immunization and boost elicited a weak
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Eriksson, Kristina, Marianne Quiding-Järbrink, Jacek Osek, et al. "Specific-Antibody-Secreting Cells in the Rectums and Genital Tracts of Nonhuman Primates following Vaccination." Infection and Immunity 66, no. 12 (1998): 5889–96. http://dx.doi.org/10.1128/iai.66.12.5889-5896.1998.

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ABSTRACT To determine optimal strategies to induce specific-antibody-secreting cells (specific ASC) in the rectal and vaginal mucosae, we immunized monkeys with a prototype mucosal immunogen, cholera toxin (CT), given locally or via gastric or parenteral administration. Repeated rectal or vaginal CT immunizations induced strong mucosal and systemic ASC responses. The mucosal responses were, however, confined to the immunization sites and comprised high levels of both specific antitoxin immunoglobulin A (IgA) and IgG. Large numbers of specific IgA and IgG ASC were detected in cell suspensions f
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Wang, Jie, Wenbo Li, Ning Li, and Beinan Wang. "Immunization with Multiple Virulence Factors Provides Maternal and Neonatal Protection against Group B Streptococcus Serotypes." Vaccines 11, no. 9 (2023): 1459. http://dx.doi.org/10.3390/vaccines11091459.

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Group B streptococcus (GBS) commonly colonizes the vaginal tract and is a leading cause of life-threatening neonatal infections and adverse pregnancy outcomes. No effective vaccine is clinically available. Conserved bacterial virulence factors, including those of GBS, have been employed as vaccine components. We investigated serotype-independent protection against GBS by intranasal immunization with six conserved GBS virulence factors (GBSV6). GBSV6 induced systemic and vaginal antibodies and T cell responses in mice. The immunity reduced mouse mortality and vaginal colonization by various GBS
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Livingston, Julie B., Shan Lu, Harriet Robinson, and Deborah J. Anderson. "Immunization of the Female Genital Tract with a DNA-Based Vaccine." Infection and Immunity 66, no. 1 (1998): 322–29. http://dx.doi.org/10.1128/iai.66.1.322-329.1998.

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ABSTRACT Vaccines are being sought for contraception and the prevention of sexually transmitted diseases. However, progress is slow in this area largely because of lack of information on induction of protective immune responses in genital tract mucosa. In this study, we investigated whether in vivo transfection with a model DNA-based antigen delivered by gene gun technology would induce an antibody response detectable in vaginal secretions. Female rats were immunized with plasmids encoding human growth hormone (HGH) under the control of a cytomegalovirus promoter (pCMV/HGH) via vaginal mucosa
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Wang, Yichuan, Yongjun Sui, Jason Steel, John Morris, and Jay Berzofsky. "Vaginal type-II mucosa acts as an inductive site during the generation of primary CD8+ T cell mucosal immune responses (P3186)." Journal of Immunology 190, no. 1_Supplement (2013): 124.4. http://dx.doi.org/10.4049/jimmunol.190.supp.124.4.

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Abstract It is widely believed that primary immune induction in type-II mucosa (vagina, mouth & cornea) occurs in the draining LNs due to a lack of mucosa-associated lymphoid tissue. In this process, naïve T cells located in the draining LNs are primed by antigen (Ag)-bearing dendritic cells migrating from the Ag-exposed mucosa. Primed T cells then travel to the mucosal site through the bloodstream. In contrast to this paradigm, we show that vaginal mucosa itself can act as an immune inductive site for generation of primary CD8+ T cell mucosal immunity. As evidence, we found that naïve C
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Medaglini, Donata, Marco R. Oggioni, and Gianni Pozzi. "Vaginal Immunization with Recombinant Gram-Positive Bacteria." American Journal of Reproductive Immunology 39, no. 3 (1998): 199–208. http://dx.doi.org/10.1111/j.1600-0897.1998.tb00354.x.

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Uehling, David T., Walter J. Hopkins, Jean Jensen, and Edward Balish. "Vaginal Immunization Against Induced Cystitis in Monkeys." Journal of Urology 137, no. 2 (1987): 327–29. http://dx.doi.org/10.1016/s0022-5347(17)44015-8.

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Hogge, Christopher James, Sabrina Helmold Hait, Gospel Enyindah-Asonye, Zuena Mushtaq, Tanya Hoang, and Marjorie Robert-Guroff. "Replicating Ad-SIV recombinant vaccines elicit mucosal humoral immunity in rhesus macaques at both rectal and vaginal sites with potential protective efficacy." Journal of Immunology 202, no. 1_Supplement (2019): 72.2. http://dx.doi.org/10.4049/jimmunol.202.supp.72.2.

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Abstract Humoral immunity, especially at mucosal sites, is important for preventing HIV acquisition. Replicating adenovirus (Ad)-SIV priming/gp120 boosting regimens have elicited mucosal immunity and protection against intrarectal SIV challenge in Rhesus macaques. Here we investigated mucosal responses in female macaques primed intranasally/orally, then intratracheally with Ad5hr-SIV(Env/gag/nef), boosted twice intramuscularly with SIV gp120, and challenged vaginally with repeated low-dose SIVmac251. Vaginal washes and rectal swabs and biopsies were obtained 3-weeks post-immunizations. gp120-s
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Dissertations / Theses on the topic "Vaginal immunization"

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Philosof, Bar. "A bacterium from the human microbiota as a vaccine vector. Efficient priming of the murine immune system by vaginal delivery of recombinant Streptococcus gordonii." Doctoral thesis, Università di Siena, 2022. http://hdl.handle.net/11365/1216735.

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The ability to prime the immune system against an antigen, and to rapidly recall this response upon antigen reencounter is a fundamental characteristic of the adaptive immune response. The association of an antigen recognized by the immune system in a certain tissue, with the same antigen encountered at a later timepoint in a different tissue, is of primary importance to obtain a systemic and effective immune response and is the foundation behind the utilization of vaccines. The study of vaccine delivery platforms that may activate the immune system in such a manner is therefore of primary imp
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Logerot, Sandrine. "Utilisation de l’interleukine-7 en immunothérapie chez des patients VIH-mauvais répondeurs immunologiques et comme adjuvant de vaccination muqueuse chez le macaque rhésus." Thesis, Sorbonne Paris Cité, 2015. http://www.theses.fr/2015USPCB111.

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L’avènement des multi-thérapies antirétrovirales a permis une réduction importante de la mortalité associée au VIH en induisant notamment la chute de la charge virale à moins de 50 copies/mL et une récupération progressive du nombre de lymphocytes T CD4+ (LT-CD4). Cependant, certains patients définis comme mauvais répondeurs immunologiques (MRI) ne parviennent pas à récupérer un taux de CD4 généralement considéré comme « protecteur » (>500cellules/µL). L’interleukine-7 (IL-7), cytokine essentielle à la thymopoïèse et à l’homéostasie lymphocytaire T, a été utilisée en étude clinique afin de
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Ambrose, Zandrea. "Immune control of SHIV in macaques upon mucosal infection of immunization /." Thesis, Connect to this title online; UW restricted, 2001. http://hdl.handle.net/1773/9290.

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Book chapters on the topic "Vaginal immunization"

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Thapar, M. A., E. L. Parr, and M. B. Parr. "Effects of intravaginal and pelvic immunization on specific antibody in mouse vaginal fluid." In Advances in Mucosal Immunology. Springer Netherlands, 1990. http://dx.doi.org/10.1007/978-94-009-1848-1_185.

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Ugwumadu, Austin. "General and specific infections in pregnancy including immunization." In Oxford Textbook of Obstetrics and Gynaecology, edited by Sabaratnam Arulkumaran, William Ledger, Lynette Denny, and Stergios Doumouchtsis. Oxford University Press, 2020. http://dx.doi.org/10.1093/med/9780198766360.003.0017.

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Until very recently, the discussion about infections in pregnancy was focused on specific microorganisms, how the pregnant mother acquired the organism and transmitted it to the fetus, the effects of the infection on fetal survival, fetal loss, fetal growth, and development, and on the long-term sequelae. The narrative applied to the ‘TORCHES’ group of infections namely toxoplasmosis, rubella, cytomegalovirus, herpes, and syphilis, dominated the scene before the emergence of newer perinatal infections such as parvovirus B19 and HIV in the later years of the twentieth century. Numerically, the
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Conference papers on the topic "Vaginal immunization"

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Орлина, Маргарита Анатольевна, Дмитрий Павлович Вергилесов, Ксения Игоревна Батаева, and Дарья Сергеевна Латышева. "PREVENTION OF HPV INFECTIONS IN ADOLESCENT GIRLS." In Наука как пространство возможностей и развития: сборник статей международной научной конференции (Санкт-Петербург, Апрель 2024). Crossref, 2024. http://dx.doi.org/10.58351/240423.2024.77.79.002.

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Вирус папилломы человека: вакцинация как приоритет профилактики является наиболее распространенным вирусом, передающимся половым путем. Он является одной из серьезных проблем здравоохранения во всем мире. Некоторые типы ВПЧ (известные как ВПЧ высокого риска) являются основными этиологическими агентами рака половых путей, таких как рак шейки матки, рак вульвы, влагалища, полового члена и анального канала, а также некоторых видов рака головы и шеи. Вакцинация против ВПЧ является приоритетной задачей в профилактике инфицирования этим вирусом. Однако относительно малая продолжительность применения
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Reports on the topic "Vaginal immunization"

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Chattopadhyay, Ishita, John Townsend, and Saumya RamaRao. Offering progesterone contraceptive vaginal rings for postpartum women through integrated family planning and immunization services. Population Council, 2015. http://dx.doi.org/10.31899/rh9.1023.

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Journal articles
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