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Journal articles on the topic 'Viral Encephalitis And Viral Meningitis'

Author: Grafiati

Published: 7 June 2025

Last updated: 2 August 2025

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1

Lyons, Jennifer L. "Viral Meningitis and Encephalitis." CONTINUUM: Lifelong Learning in Neurology 24, no. 5 (2018): 1284–97. http://dx.doi.org/10.1212/con.0000000000000650.

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Rice, Philip. "Viral Meningitis and Encephalitis." Medicine 29, no. 2 (2001): 54–58. http://dx.doi.org/10.1383/medc.29.2.54.27525.

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Rice, Philip. "Viral meningitis and encephalitis." Medicine 33, no. 4 (2005): 60–63. http://dx.doi.org/10.1383/medc.33.4.60.64356.

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Rubeiz, Helene, and Raymond Roos. "Viral Meningitis and Encephalitis." Seminars in Neurology 12, no. 03 (1992): 165–77. http://dx.doi.org/10.1055/s-2008-1041173.

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Rice, Philip. "Viral meningitis and encephalitis." Medicine 37, no. 11 (2009): 574–78. http://dx.doi.org/10.1016/j.mpmed.2009.08.003.

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Rice, Philip. "Viral meningitis and encephalitis." Medicine 41, no. 12 (2013): 678–82. http://dx.doi.org/10.1016/j.mpmed.2013.09.005.

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Rice, Philip. "Viral meningitis and encephalitis." Medicine 45, no. 11 (2017): 664–69. http://dx.doi.org/10.1016/j.mpmed.2017.08.009.

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DeBiasi, Roberta L., and Kenneth L. Tyler. "VIRAL MENINGITIS AND ENCEPHALITIS." CONTINUUM: Lifelong Learning in Neurology 12 (April 2006): 58–94. http://dx.doi.org/10.1212/01.con.0000290450.11098.b1.

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Tuppeny, Misti. "Viral Meningitis and Encephalitis." Critical Care Nursing Clinics of North America 25, no. 3 (2013): 363–80. http://dx.doi.org/10.1016/j.ccell.2013.04.003.

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Imamba, A., P. Kalima, G. Kwenda, et al. "Aetiology of encephalitis and meningitis in children aged 1-59 months admitted to the Children's Hospital, Lusaka, Zambia." Medical Journal of Zambia 46, no. 2 (2019): 81–89. http://dx.doi.org/10.55320/mjz.46.2.107.

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Background: Meningitis and encephalitis are important causes of admissions and mortality in Zambia. Apart from bacterial causes, no data is available on viral agents that cause disease at the Children's Hospital, Lusaka, Zambia. We conducted a prospective descriptive study to determine the viral and bacterial causes of encephalitis and meningitis in children aged 1-59 months. Methods: From November 2016 to February 2018, we collected cerebrospinal fluid (CSF) samples and clinical details from children admitted to the inpatient wards with encephalitis and meningitis. Macroscopic examinati

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Imamba, A., P. Kalima, G. Kwenda, et al. "Aetiology of Encephalitis and Meningitis in Children Aged 1-59 Months Admitted to the Children's Hospital, Lusaka, Zambia." Medical Journal of Zambia 46, no. 2 (2019): 81–89. http://dx.doi.org/10.55320/mjz.46.2.503.

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Background: Meningitis and encephalitis are important causes of admissions and mortality in Zambia. Apart from bacterial causes, no data is available on viral agents that cause disease at the Children's Hospital, Lusaka, Zambia. We conducted a prospective descriptive study to determine the viral and bacterial causes of encephalitis andmeningitis in children aged 1-59 months. Methods: From November 2016 to February 2018, we collected cerebrospinal fluid (CSF) samples and clinical details from children admitted to the inpatient wards with encephalitis and meningitis. Macroscopic examinatio

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Egorova, E. S., N. V. Skripchenko, А. А. Vilnits, L. A. Alekseeva, and E. Yu Skripchenko. "Comparative analysis of hemostatic disorders in bacterial and viral neuroinfections at a children." CHILDREN INFECTIONS 19, no. 2 (2020): 5–13. http://dx.doi.org/10.22627/2072-8107-2020-19-2-5-13.

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Purulent meningitis and viral encephalitis are the most common neuroinfections in children. The severity of the lesion, the frequency of disabling manifestations, as well as high mortality, determine the relevance of their study. Violations of hemostasis both in purulent meningitis and in viral encephalitis are some of the important pathogenetic mechanisms that determine the nature of the course and the similarity of the disease. The material for clinical, laboratory, and radiation studies was 100 children with purulent meningitis of various etiologies and viral encephalitis from the age of 1

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Banović, Pavle, Adrian Alberto Díaz-Sánchez, Selena Đurić, et al. "Unexpected TBEV Seropositivity in Serbian Patients Who Recovered from Viral Meningitis and Encephalitis." Pathogens 11, no. 3 (2022): 371. http://dx.doi.org/10.3390/pathogens11030371.

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The tick-borne encephalitis virus (TBEV) causes a life-threatening disease named Tick-borne encephalitis (TBE). The clinical symptoms associated with TBE range from non-specific to severe inflammation of the central nervous system and are very similar to the clinical presentation of other viral meningitis/encephalitis. In consequence, TBE is often misclassified by clinical physicians, mainly in the non-identified high-risk areas where none or only a few TBE cases have been reported. Considering this situation, we hypothesized that among persons from northern Serbia who recovered from viral men

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Romero, José R., and Jason G. Newland. "Viral meningitis and encephalitis: Traditional and emerging viral agents." Seminars in Pediatric Infectious Diseases 14, no. 2 (2003): 72–82. http://dx.doi.org/10.1053/spid.2003.127223.

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Jawad, Yasmeen, Shaimaa Jawad, and Zainab Hamid. "Review on Viral Encephalitis-." Journal of the Faculty of Medicine Baghdad 64, no. 3 (2022): 112–16. http://dx.doi.org/10.32007/jfacmedbagdad.6431918.

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Background: Inflammation of the brain parenchyma brought on by a virus is known as viral encephalitis. It coexists frequently with viral meningitis and is the most prevalent kind of encephalitis. Objectives: To throw light on viral encephalitis, its types, epidemiology, symptoms and complications. Results: Although it can affect people of all ages, viral infections are the most prevalent cause of viral encephalitis, which is typically seen in young children and old people. Arboviruses, rhabdoviruses, enteroviruses, herpesviruses, retroviruses, orthomyxoviruses, orthopneumoviruses, and coronavi

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Andreula, C. F., G. Marano, and I. Kambas. "Viral Encephalitis." Rivista di Neuroradiologia 10, no. 3 (1997): 357–68. http://dx.doi.org/10.1177/197140099701000308.

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Patients with viral infections of the central nervous system are encountered daily, but it is often difficult to establish a correct differential diagnosis. This paper attempts to “reorganize” our knowledge of such infections. Our starting point was virology, defining the different viruses according to the latest classifications, distinguishing RNA viruses from DNA viruses, assessing capsid shape and dividing each family into genera and species of interest. We then determined the pathophysiology: from initial viraemia we considered the mechanisms of CNS penetration and the pathological changes

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Kamble, Aarav S., Akshay P. Kute, Anitha M. S., and Pooja Badadhe. "Hemorrhagic viral encephalitis: an unusual presentation of chikungunya viral infection." International Journal of Research in Medical Sciences 12, no. 11 (2024): 4339–41. http://dx.doi.org/10.18203/2320-6012.ijrms20243399.

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Chikungunya is a mosquito borne alpha virus that is implicated in causation of viral fever with arthralgia which is literally translated as “to become contorted” depicting the severity of the pain. The infection in itself is self-limiting, however the joint pain and myalgia associated with it might linger till weeks, months or even years. Some cases also progress to the viral fever associated complications such as meningitis, encephalitis and Guillain–Barré syndrome. Though, some cases of encephalitis have been reported, it is a relatively rare complication. Here we present a case of a 17 year

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Lewis, H., and F. M. Gibbon. "Management of viral meningitis and encephalitis." Current Paediatrics 10, no. 2 (2000): 110–15. http://dx.doi.org/10.1054/cupe.2000.0095.

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Gundamraj, Vaishnavi, and Rodrigo Hasbun. "Viral meningitis and encephalitis: an update." Current Opinion in Infectious Diseases 36, no. 3 (2023): 177–85. http://dx.doi.org/10.1097/qco.0000000000000922.

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Jawad, Aiyar Shakir. "Spectrum of central nervous system infections in neurosciences hospital in two years : a retrospective study." AL-Kindy College Medical Journal 16, no. 1 (2020): 67–73. http://dx.doi.org/10.47723/kcmj.v16i1.197.

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Background :Infectious disorders in general have high morbidity and mortality.. CNS infections include many disorders like bacterial meningitis, tuberculous and other subacute and chronic meningitis, viral meningitis, cerebral abscess, spinal cord infections, and others.Objective: To assess our locality about prevalence of CNS infections , to have more awareness regarding CNS infections, and to try to find the proper way to reduce their prevalence and to treat them in appropriate way.Method :We revised the records of all the cases of CNS infections excluding cases of spinal cord infections who

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Kelly, Tara A., Piaras O’Lorcain, Joanne Moran, et al. "Underreporting of Viral Encephalitis and Viral Meningitis, Ireland, 2005–2008." Emerging Infectious Diseases 19, no. 9 (2013): 1428–36. http://dx.doi.org/10.3201/eid1909.130201.

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Dongol, Srijana, Shreema Shrestha, Narayan Shrestha, and J. Adhikari. "Clinical Profile and Outcome of Acute Encephalitis Syndrome in Dhulikhel Hospital of Nepal." Journal of Nepal Paediatric Society 32, no. 3 (2013): 201–5. http://dx.doi.org/10.3126/jnps.v32i3.6683.

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Introduction: Acute encephalitis syndrome (AES) is a constellation of clinical signs and or symptoms i.e. acute fever with acute change in mental status. AES may be present as encephalitis, meningoencephalitis or meningitis. It can be associated with severe complication, including impaired consciousness, seizure, limb paresis or death. Materials and Methods: Study consisted of retrospective analysis of hospital records of children up to 16 years of age admitted with diagnosis of AES in the department of Paediatrics Dhulikhel Hospital, Kathmandu University Teaching Hospital, Dhulikhel Kavre fro

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Treepong, C., T. Termglinchan, and M. Apiwattanakul. "Viral meningitis triggers anti-NMDA receptor encephalitis." Journal of the Neurological Sciences 333 (October 2013): e605. http://dx.doi.org/10.1016/j.jns.2013.07.2110.

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Bakir, T. F. "Viral Meningitis and Encephalitis in Saudi Arabia." Journal of Tropical Pediatrics 35, no. 5 (1989): 211–13. http://dx.doi.org/10.1093/tropej/35.5.211-a.

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Uddin, Mohammad Najim, and Md Mahtab Uddin Hassan. "Study of Etiological Pattern of Acute Meningo-Encephalitis Syndrome." Bangladesh Journal of Neuroscience 34, no. 1 (2018): 45–51. http://dx.doi.org/10.3329/bjn.v34i1.57535.

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Background: Acute meningo-encephalitis syndrome is a medical emergency which claim urgent management. So the objectives of the present study was to find out aetiological factors and differentiating parameter between different types acute meningoencephalitis syndrome with minimum investigation. Methods: This hospital based observational study was carried out in medicine units of Chittagong Medical College. Fifty cases were studied who present with acute onset fever with central nervous system dysfunction. Results: In this study it reveals that hospital rate of bacterial meningitis was 26%, vira

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Nau, R. "Diagnosis and treatment of bacterial meningitis." Neurology Bulletin XXXI, no. 1-4 (1999): 49–53. http://dx.doi.org/10.17816/nb80930.

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In Germany, cases of meningitis and encephalitis are registered by the epidemiological service. In 1988, the Republican Ministry of Health received 4301 reports of these diseases: 488 cases of meningococcal meningitis, 1192 of bacterial meningitis of a different etiology, 962 of viral meningoencephalitis, and 1659 of meningitis and encephalitis of a different etiology (Phn, 1990).

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Stavrou, Maria, Jing Ming Yeo, Alexander David Slater, Sarosh Irani, and Peter Foley. "060 Fulminant meningitis as a presenting feature of anti-NMDA receptor encephalitis." Journal of Neurology, Neurosurgery & Psychiatry 90, no. 12 (2019): A24.2—A24. http://dx.doi.org/10.1136/jnnp-2019-abn-2.79.

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Anti-NMDA receptor encephalitis is a well-recognised immunotherapy-responsive condition which often occurs as a paraneoplastic phenomenon. A typical presentation is in a young individual with a viral-like prodrome followed by the development of severe psychiatric symptoms, memory loss, seizures, reduced consciousness and sometimes orofacial dyskinesias, and progression to autonomic and respiratory instability. Fulminant meningitis is a very rare presenting feature of anti-NMDA receptor encephalitis with our literature search only revealing one other reported case.We present a case of a 33-year

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Jitender, Sharma, and Sharma Anmol. "Application of BioFire Meningitis Panel for Pathogen Identification and its Impact on Antimicrobial Therapy in Meningitis Cases at a Tertiary Care Centre in India." International Journal of Pharmaceutical and Clinical Research 16, no. 12 (2024): 515–24. https://doi.org/10.5281/zenodo.14593432.

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<strong>Background and Aim:</strong> Meningitis remains a significant public health issue in India to date for particular groups of people, including children, older adults and immunocompromised. This study aimed to evaluate the diagnostic performance, clinical usefulness and cost-effectiveness of a panel of 500 patients in the Indian setting. <strong>Materials and Methods:</strong> This prospective, observational study was conducted in a tertiary care hospital in India for one year after fulfilling the inclusion and exclusion criteria. The sensitivity and specificity of BioFire

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Soares, Cristiane N., Mauro J. Cabral Castro, José M. Peralta, Marcos R. G. de Freitas, and Marzia Puccioni-Sohler. "Is West Nile virus a potential cause of central nervous system infection in Brazil?" Arquivos de Neuro-Psiquiatria 68, no. 5 (2010): 761–63. http://dx.doi.org/10.1590/s0004-282x2010000500016.

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Meningitis and encephalitis are complications of West Nile virus (WNV) infection. Although WNV is endemic in North America, the virus has recently been reported in Colombia and Argentina. Investigation of WNV in Brazil is important since this virus has never been studied previously in this country. OBJECTIVE: To investigate the presence of WNV infection in viral encephalitis/meningitis cases of unknown etiology in the city of Rio de Janeiro, Brazil. METHOD: Thirty-seven adults with viral meningitis/encephalitis had their serum and CSF tested for WNV antibodies using the ELISA method. RESULTS:

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N., Monika, Rohith M. G., Ravi K., and Someshwar A. Kandagal. "Clinical profile and outcome of patients with meningoencephalitis in a tertiary care hospital." International Journal of Research in Medical Sciences 11, no. 3 (2023): 1012–18. http://dx.doi.org/10.18203/2320-6012.ijrms20230591.

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Background: Encephalitis is an important cause of morbidity, mortality, and permanent neurologic sequelae globally. Causes are diverse and include viral and non-viral infections. In the emergency setting differentiating the bacterial from other causes such as viral, fungal, tubercular, toxic or autoimmune causes is extremely difficult. Although plenty of literature is available on meningitis, the clinic-etiological profile and outcome with meningoencephalitis remains not that well studied, except for in paediatric population. Methods: The present prospective observational study included 75 pat

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Jayaraman, Kalaivani, Rajeswaran Rangasami, and Anupama Chandrasekharan. "Magnetic Resonance Imaging Findings in Viral Encephalitis: A Pictorial Essay." Journal of Neurosciences in Rural Practice 09, no. 04 (2018): 556–60. http://dx.doi.org/10.4103/jnrp.jnrp_120_18.

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ABSTRACTViral encephalitis by definition is the result of human virus affecting the brain and sparing the meninges. The other nervous system manifestations are meningitis, meningoencephalitis, encephalomyelitis, and encephalomyeloradiculitis. Encephalitis can involve any age group from children to old people. The severity of the disease depends on the viral agent and the host immune system. The patient can present with fever, headache, seizure, neurological deficit, or altered sensorium. Laboratory investigations, imaging, and cerebrospinal fluid analysis are crucial in the diagnosis of enceph

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Kwok, Chun Shing, Kirellos Said Abbas, Adnan I. Qureshi, Duwarakan Satchithananda, and Josip Andelo Borovac. "The Impact of Concomitant Diagnosis of Viral Infections on in-Hospital Mortality in Patients Hospitalized with a Diagnosis of Heart Failure in the United States: Insights from the National Inpatient Sample." Viruses 14, no. 11 (2022): 2418. http://dx.doi.org/10.3390/v14112418.

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The impact of viral infections on patients admitted with a diagnosis of heart failure is not well understood. We conducted a retrospective cohort study using data from the National Inpatient Sample in the United States to evaluate the proportion of admissions with a diagnosis of heart failure and viral infections, and we explored how viral infections had impact on in-hospital mortality and length of stay. There were a total of 20,713,539 admission records with a diagnosis of heart failure included in the analysis and 3.8% had a concomitant diagnosis of viral infection. The mean length of stay

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Al-Mekhlafi, Amani, Kurt-Wolfram Sühs, Sven Schuchardt, et al. "Elevated Free Phosphatidylcholine Levels in Cerebrospinal Fluid Distinguish Bacterial from Viral CNS Infections." Cells 10, no. 5 (2021): 1115. http://dx.doi.org/10.3390/cells10051115.

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The identification of CSF biomarkers for bacterial meningitis can potentially improve diagnosis and understanding of pathogenesis, and the differentiation from viral CNS infections is of particular clinical importance. Considering that substantial changes in CSF metabolites in CNS infections have recently been demonstrated, we compared concentrations of 188 metabolites in CSF samples from patients with bacterial meningitis (n = 32), viral meningitis/encephalitis (n = 34), and noninflamed controls (n = 66). Metabolite reprogramming in bacterial meningitis was greatest among phosphatidylcholines

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Vanood, Aimen, Alexandra Hospodar, and Christopher F. Carpenter. "101. Diagnostic Utility of a Multiplex PCR Meningitis/Encephalitis Panel and Impact on Antibiotic Use." Open Forum Infectious Diseases 7, Supplement_1 (2020): S65. http://dx.doi.org/10.1093/ofid/ofaa439.146.

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Abstract Background The detection and identification of meningitis and encephalitis pathogens from CSF via traditional microbiologic methods may take several hours to days. The BioFire FilmArray Meningitis/Encephalitis Panel (BioFire), approved by the FDA in 2015, can detect 14 different pathogens within one hour, providing a faster time to diagnosis of a broad range of pathogens. The purpose of this study was to examine the impact of BioFire on length of hospital stay and duration of antibiotic use. Methods We conducted a retrospective chart review of patients diagnosed meningitis/encephaliti

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Kumar, Durgesh, Dinesh Kumar, Alok Tiwari, Nishant Sharma, Rajesh Kumar Yadav, and Krishan Mohan Shukla. "Cerebrospinal Fluid and Serum C-Reactive Protein among Children with Acute Encephalitis Syndrome." Journal of Pediatric Infectious Diseases 16, no. 03 (2021): 111–15. http://dx.doi.org/10.1055/s-0041-1724020.

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Abstract Objectives This study aimed to evaluate the positivity of C-reactive protein (CRP) in cerebrospinal fluid (CSF) and serum in children presented with clinical diagnosis of acute encephalitis syndrome (AES). Methods A total of 164 children between 6 months and 14 years with clinical diagnosis of AES were investigated. Qualitative CRP (slide agglutination) was determined in CSF and serum sample of each patient. On the basis of clinical examination and investigations, all the patients were divided into four groups as pyogenic meningitis, viral encephalitis, tuberculous meningitis, and cer

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Li, Yijie, Jing Liu, Yimin Zhu, et al. "Alterations of oral microbiota in Chinese children with viral encephalitis and/or viral meningitis." Journal of Microbiology 60, no. 4 (2022): 429–37. http://dx.doi.org/10.1007/s12275-022-1560-y.

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Marszałek, Agata, Weronika Górska, Artur Łukawski, Carlo Bieńkowski, and Maria Pokorska-Śpiewak. "Could the Identification of Skin Lesions Be Beneficial for the Differential Diagnosis of Viral Meningitis?" Zoonotic Diseases 5, no. 2 (2025): 16. https://doi.org/10.3390/zoonoticdis5020016.

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Viral infections may vary from mild to severe, manifesting with a wide range of symptoms, including skin lesions, influenza-like symptoms, or meningitis/meningoencephalitis signs. Viruses that cause both skin lesions and meningitis comprise, e.g., Enteroviruses (EVs) and Herpes viruses (HV). EVs are responsible for approximately 90% of viral meningitis cases. They occur frequently among children under 3 years of age and are characterized by various types of rash. HV infections are responsible for up to 18% of viral meningitis, mostly among adults or older children. Most patients with viral men

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Le Bars, Hervé, Neil Madany, Claudie Lamoureux, et al. "Evaluation of the Performance Characteristics of a New POC Multiplex PCR Assay for the Diagnosis of Viral and Bacterial Neuromeningeal Infections." Diagnostics 13, no. 6 (2023): 1110. http://dx.doi.org/10.3390/diagnostics13061110.

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Point-of-care syndromic PCR (POC SPCR) assays are useful tools for the rapid detection of the most common causative agents of community-acquired infections responsible for meningitis and encephalitis infections. We evaluated the performance characteristics of the new QIAstat-Dx® Meningitis/Encephalitis panel (QS) compared to the laboratory reference methods and the POC SPCR Biofire® FilmArray® Meningitis Encephalitis Panel (FA). Viral (Enterovirus, Parechovirus, HSV-1, HSV-2, HHV-6, VZV) and bacterial (E. coli K1, H. influenzae, L. monocytogenes, encapsulated N. meningitidis, M. pneumoniae, S.

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Tahsin Gozdas, Hasan, Ahmet Dogan, Hamish Wright, and Andrew Fox-Lewis. "Laboratory findings in acute bacterial meningitis and acute viral encephalitis." New Zealand Medical Journal 137, no. 1592 (2024): 103–4. http://dx.doi.org/10.26635/6965.6468.

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Jha, Rajiv, Pankaj Jalan, Rajiv Shah, and Adarsh Chaturvedi. "Anti- NMDAR Encephalitis in a 28 years old female: Revisited." Nepal Journal of Neuroscience 20, no. 3 (2023): 70–72. http://dx.doi.org/10.3126/njn.v20i3.56715.

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Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is the prevailing subtype of autoimmune encephalitis, commonly misdiagnosed initially as infectious encephalitis due to its symptomatology resembling that of viral encephalitis and meningitis. The condition exhibits a higher incidence in females, with a gender ratio of 4:1 compared to males. While electroencephalogram (EEG) and magnetic resonance imaging (MRI) aid in the diagnostic process, the presence of antibodies in the cerebrospinal fluid (CSF) serves as the definitive confirmation. Autoimmune encephalitis typically presents with a s

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Goodrich, Nathaniel, Aleisha M. Nabower, Prabi Rajbhandari, et al. "341. Clinical and Laboratory Data in Patients with Viral and Bacterial Meningitis in Conjunction with FilmArray Meningitis/Encephalitis Panel Use: A Multi-Site Retrospective Cohort Study." Open Forum Infectious Diseases 7, Supplement_1 (2020): S240—S241. http://dx.doi.org/10.1093/ofid/ofaa439.536.

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Abstract Background The ability to quickly recognize and diagnose meningitis is a critical component in its management. The use of the FilmArray Meningitis/Encephalitis (ME) panel has made pathogen identification easier and faster. Although literature exists regarding clinical and laboratory data in patients with bacterial meningitis, less is known about the characteristics of viral meningitis caused by viruses detected by the ME panel This study aims to compare differences in clinical and laboratory characteristics between viral and bacterial meningitis identified by the ME panel. Methods We

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Yavru, Sibel, Mehmet Özdemir, and Bahadır Feyzioğlu. "Laboratory Diagnosis of Pediatric Herpesvirus Infections of the Central Nervous System by a Multiplex Polymerase Chain Reaction Assay and Intrathecal Antibodies." Journal of Pediatric Infectious Diseases 13, no. 03 (2018): 178–84. http://dx.doi.org/10.1055/s-0038-1639616.

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Abstract Introduction Central nervous system (CNS) viral infections are a serious problem requiring accurate diagnosis and treatment. Human herpesviruses (HHVs) are an important cause of these infections. Recent research has focused on new diagnostic methods allowing accurate and rapid identification of viral infections because there are still diagnostic difficulties for these infections. This study was done to determine the etiologic role of human herpes viruses and to obtain information that will contribute to the diagnostic algorithm in suspected cases of viral encephalitis or aseptic menin

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Vasavada, Halak J., Snehal V. Patel, Kuldip A. Detroja, Aakanksha R. Patel, and Mitsu N. Patel. "Study of clinicodemographic profile of acute central nervous system infection in children and its correlation with neuroimaging." International Journal of Contemporary Pediatrics 9, no. 4 (2022): 342. http://dx.doi.org/10.18203/2349-3291.ijcp20220759.

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Background: Infection of central nervous system (CNS) is most common cause of fever associated with signs and symptoms of CNS disease in children. Viral infections of CNS are more common than other infections. Radiology and pathology go together in understanding etiology causing CNS infections which have similar clinical manifestations making specific diagnosis difficult. The present study aims to study the utility of different neuroimaging patterns in diagnosis of acute CNS infection. Aims include: to study utility and pattern of neuroimaging in CNS infection in paediatric age group, and to s

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Zineb Nassiri, Salma Amrani Idrissi, Asmaa Lamrani Hanchi, and Nabila Soraa. "Viral infections of the central nervous system." GSC Advanced Research and Reviews 14, no. 3 (2023): 209–18. http://dx.doi.org/10.30574/gscarr.2023.14.3.0085.

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Background: Viral infections of the central nervous system are an important cause of morbidity and mortality. Aim: This study was designed to identify the viruses responsible for viral involvement of the CNS and to determine their frequency, circulation pattern, and seasonality. Methods: Detection, by multiplex PCR using FilmArray® Meningitis/Encephalitis panel, of viruses in the cerebrospinal fluid of all patients admitted for suspected viral infection of central nervous system and requiring hospitalization in the various departments of the Mohamed VI University Hospital of Marrakesh. Results

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Zineb, Nassiri, Amrani Idrissi Salma, Lamrani Hanchi Asmaa, and Soraa Nabila. "Viral infections of the central nervous system." GSC Advanced Research and Reviews 14, no. 3 (2023): 209–18. https://doi.org/10.5281/zenodo.7928802.

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<strong>Background</strong>: Viral infections of the central nervous system are an important cause of morbidity and mortality. <strong>Aim</strong>: This study was designed to identify the viruses responsible for viral involvement of the CNS and to determine their frequency, circulation pattern, and seasonality. <strong>Methods</strong>: Detection, by multiplex PCR using FilmArray® Meningitis/Encephalitis panel, of viruses in the cerebrospinal fluid of all patients admitted for suspected viral infection of central nervous system and requiring hospitalization in the various departments of t

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Aguilera, Elizabeth A., Shelby Simar, Susan H. Wootton, Rodrigo Hasbun, and Rodrigo Hasbun. "259. Impact of a Multiplex Meningitis and Encephalitis PCR on the Management of CNS Infections in Adults and Children, Houston, Texas." Open Forum Infectious Diseases 8, Supplement_1 (2021): S235—S236. http://dx.doi.org/10.1093/ofid/ofab466.461.

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Abstract Background The majority of adults and children with meningitis and encephalitis have unknown etiologies fostering universal admission, prolonged length of stay, empirical antibiotic and antiviral therapies. A qualitative multiplexed nucleic acid-based in vitro diagnostic test (FilmArray) is helping clinicians identify organisms and improve clinical outcomes. Methods Patients presenting between July 5, 2018, to April 26, 2021, with meningitis or encephalitis, cerebrospinal fluid (CSF) with WBC &gt;5 cells/mm3, and leftover CSF were available for testing. All CSF specimens underwent

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Zamarina, Т. V., N. P. Khrapova, I. A. Barkova, et al. "THE INFORMATIVE VALUE OF IMMUNOLOGICAL AND GENETIC TESTS IN THE DIAGNOSIS WEST NILE FEVER." Journal of Volgograd State Medical University 76, no. 4 (2020): 42–45. http://dx.doi.org/10.19163/1994-9480-2020-4(76)-42-45.

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We used ELISA and PCR for laboratory verification of West Nile fever (MUC 4.2.3009-12). We analyzed serum and whole blood samples which had been sent to West Nile fever reference monitoring centre in 2018–2019. A total of 270 blood samples obtained from patients with presumed viral encephalitis of unknown etiology, acute respiratory viral infection, acute respiratory viral infection, meningitis, acute gastroenteritis were analyzed. Antibodies against WNV were detected in 193 (71,4 %) blood samples, while 146 samples were found to be capable of developing an immune response with viral RNA not b

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Read, Steven J., and John B. Kurtz. "Laboratory Diagnosis of Common Viral Infections of the Central Nervous System by Using a Single Multiplex PCR Screening Assay." Journal of Clinical Microbiology 37, no. 5 (1999): 1352–55. http://dx.doi.org/10.1128/jcm.37.5.1352-1355.1999.

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A multiplex PCR assay that detects the four commonest causes of viral meningitis and encephalitis in the United Kingdom (herpes simplex virus [HSV] type 1 [HSV-1], HSV type 2 [HSV-2], varicella-zoster virus [VZV], and enteroviruses) was developed, and its sensitivity was compared with those of similar assays described previously for this application. Compared to the previous assays, this single multiplex PCR assay had higher molecular sensitivities for the detection for each of the viruses and improved utility for routine use in a diagnostic laboratory. The assay was used to test a series of 1

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Liberalesso, Paulo Breno Noronha, Izabella Celidônio Bertoldo da Silva, Karlin Fabianne Klagenberg, Ari Leon Jurkiewicz, Bianca Simone Zeigelboim, and Victor Horácio Costa Júnior. "Incidence and risk factors for seizures in central nervous system infections in childhood." Journal of Epilepsy and Clinical Neurophysiology 15, no. 2 (2009): 83–88. http://dx.doi.org/10.1590/s1676-26492009000200007.

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INTRODUCTION: The infections of the central nervous system remain as a public health problem in several countries and there is a direct relation between poverty and underdevelopment with high mortality and morbidity rates. Seizures represents a complication related to infections of the central nervous system, are considered a clinical emergency and requiring neurological investigation. OBJECTIVE: In this article, we propose to describe the incidence and risk factors for seizures in central nervous system infections in childhood. METHODS: a retrospective study was performed between October 2007

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Schibler, Brito, Zanella, et al. "Viral Sequences Detection by High-Throughput Sequencing in Cerebrospinal Fluid of Individuals with and without Central Nervous System Disease." Genes 10, no. 8 (2019): 625. http://dx.doi.org/10.3390/genes10080625.

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: Meningitis, encephalitis, and myelitis are various forms of acute central nervous system (CNS) inflammation, which can coexist and lead to serious sequelae. Known aetiologies include infections and immune-mediated processes. Despite advances in clinical microbiology over the past decades, the cause of acute CNS inflammation remains unknown in approximately 50% of cases. High-throughput sequencing was performed to search for viral sequences in cerebrospinal fluid (CSF) samples collected from 26 patients considered to have acute CNS inflammation of unknown origin, and 10 patients with defined

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