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Journal articles on the topic 'Wound Modulation'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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1

Lin, Pei-Hui, Matthew Sermersheim, Haichang Li, Peter Lee, Steven Steinberg, and Jianjie Ma. "Zinc in Wound Healing Modulation." Nutrients 10, no. 1 (2017): 16. http://dx.doi.org/10.3390/nu10010016.

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2

Ram, Jagat, Archana Malik, and ParulChawla Gupta. "Wound modulation with botulinum toxin." Journal of Ophthalmic and Vision Research 11, no. 2 (2016): 240. http://dx.doi.org/10.4103/2008-322x.183919.

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3

Seibold, Leonard K., Mark B. Sherwood, and Malik Y. Kahook. "Wound Modulation After Filtration Surgery." Survey of Ophthalmology 57, no. 6 (2012): 530–50. http://dx.doi.org/10.1016/j.survophthal.2012.01.008.

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4

Davidson, Jeffrey M., and Matthew D. Breyer. "Inflammatory Modulation and Wound Repair." Journal of Investigative Dermatology 120, no. 5 (2003): xi—xii. http://dx.doi.org/10.1046/j.1523-1747.2003.12154.x.

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5

Cordeiro, M. Francesca, Dilani Siriwardena, Lydia Chang, and Peng T. Khaw. "Wound healing modulation after glaucoma surgery." Current Opinion in Ophthalmology 11, no. 2 (2000): 121–26. http://dx.doi.org/10.1097/00055735-200004000-00010.

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6

Grinnell, F. "Wound repair, keratinocyte activation and integrin modulation." Journal of Cell Science 101, no. 1 (1992): 1–5. http://dx.doi.org/10.1242/jcs.101.1.1.

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7

Costa, Vital P., George L. Spaeth, Richard A. Eiferman, and Silvia Orengo-Nania. "Wound Healing Modulation in Glaucoma Filtration Surgery." Ophthalmic Surgery, Lasers and Imaging Retina 24, no. 3 (1993): 152–70. http://dx.doi.org/10.3928/1542-8877-19930301-04.

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8

Atreides, Sean-Paul A., Gregory L. Skuta, and Adam C. Reynolds. "Wound Healing Modulation in Glaucoma Filtering Surgery." International Ophthalmology Clinics 44, no. 2 (2004): 61–106. http://dx.doi.org/10.1097/00004397-200404420-00007.

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9

Gorti, Goutham Krishna, and R. James Koch. "Modulation of wound healing and scar formation." Current Opinion in Otolaryngology & Head and Neck Surgery 10, no. 4 (2002): 287–91. http://dx.doi.org/10.1097/00020840-200208000-00009.

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10

Khaw, Peng T., Lydia Chang, Tina T. L. Wong, Anna Mead, Julie T. Daniels, and M. Francesca Cordeiro. "Modulation of wound healing after glaucoma surgery." Current Opinion in Ophthalmology 12, no. 2 (2001): 143–48. http://dx.doi.org/10.1097/00055735-200104000-00011.

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&NA;. "Modulation of wound healing after glaucoma surgery." Current Opinion in Ophthalmology 12, no. 3 (2001): 235. http://dx.doi.org/10.1097/00055735-200106000-00017.

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12

Matar, S., A. Petit, P. Kanaan, et al. "528 Serotonin modulation improves cutaneous wound healing." Journal of Investigative Dermatology 144, no. 12 (2024): S319. http://dx.doi.org/10.1016/j.jid.2024.10.541.

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13

Zada, Mark, Ushasree Pattamatta, and Andrew White. "Modulation of Fibroblasts in Conjunctival Wound Healing." Ophthalmology 125, no. 2 (2018): 179–92. http://dx.doi.org/10.1016/j.ophtha.2017.08.028.

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14

PULLAR, C., C. MANABATHIDALGO, R. BOLAJI та R. ISSEROFF. "β-Adrenergic receptor modulation of wound repair". Pharmacological Research 58, № 2 (2008): 158–64. http://dx.doi.org/10.1016/j.phrs.2008.07.012.

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15

VAN BERGEN, T. "Modulation of wound healing after glaucoma surgery." Acta Ophthalmologica 86 (September 4, 2008): 0. http://dx.doi.org/10.1111/j.1755-3768.2008.4264.x.

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16

Ramey-Ward, Allison N., Shakesia Smith, Howard Walthall, and Thomas H. Barrows. "Human Keratin Matrices Suppress Matrix Metalloproteinase Activity to Support Wound Healing." International Journal of Molecular Sciences 25, no. 23 (2024): 12898. https://doi.org/10.3390/ijms252312898.

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Elevated protease activity is a hallmark of non-healing chronic wounds. Though multiple biomaterials exist that are successful in treating wounds, their roles in modulating the enzymatic environment of the wound are only beginning to be elucidated. Because keratin has long been known to be resistant to degradation by most enzymes, we studied a keratin biomaterial, the human keratin matrix (HKM), in the presence of enzymes identified to contribute to wound chronicity: neutrophil-derived elastase (NE), matrix metalloproteinase 1 (MMP-1), and MMP-9. Upon finding the suppression of MMP-9 activity

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17

Radaykina, M. V., A. V. Zolotarev, E. V. Karlova, V. M. Malov, and E. B. Eroshevskaya. "Pharmacological modulation of wound healing in glaucoma surgery." Aspirantskiy Vestnik Povolzhiya 23, no. 4 (2023): 51–58. http://dx.doi.org/10.55531/2072-2354.2023.23.4.51-58.

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Excessive scarring in the area of hypotensive glaucoma surgery is still a challenge in ophthalmology as it is the main cause of postoperative IOP elevation. The antiproliferative pharmacologic agents currently used for wound healing modulation are either not effective enough or have poor safety profile. The review provides a brief description of wound healing physiology including cytokines involved in it. It also represents the mechanisms of action and effects of drugs that influence wound healing and are used as antiproliferative agents for prevention of excessive scarring in glaucoma s

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18

Malyugin, B. E., A. V. Sidorova, A. V. Starostina, et al. "Pharmacological modulation of wound healing in glaucoma surgery." Vestnik oftal'mologii 138, no. 4 (2022): 137. http://dx.doi.org/10.17116/oftalma2022138041137.

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19

Malyugin, B. E., A. V. Sidorova, A. V. Starostina, et al. "Pharmacological modulation of wound healing in glaucoma surgery." Vestnik oftal'mologii 138, no. 4 (2022): 136. http://dx.doi.org/10.17116/oftalma2022138041136.

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20

Engelmayer, Jose, Paul Blezinger, and Atul Varadhachary. "Talactoferrin Stimulates Wound Healing With Modulation of Inflammation." Journal of Surgical Research 149, no. 2 (2008): 278–86. http://dx.doi.org/10.1016/j.jss.2007.12.754.

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21

Jurjus, Abdo, Bishara S. Atiyeh, Inaya M. Abdallah, et al. "Pharmacological modulation of wound healing in experimental burns." Burns 33, no. 7 (2007): 892–907. http://dx.doi.org/10.1016/j.burns.2006.10.406.

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22

Yaakub, Azhany, Siti-Fairuz Mohd-Yusof, Azlina Ahmad, et al. "Modulation Agents of Wound Healing in Ocular Surgeries." JANUARY 2024 20, no. 1 (2024): 293–303. http://dx.doi.org/10.47836/mjmhs.20.1.37.

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Wound healing is a complex process that includes haemostasis and inflammation, followed by a proliferation period and repair and finally remodelling. Ocular surgeries, particularly in glaucoma cases, aim at minimal fibrosis to preserve the function of trabeculectomy as an alternative pathway for aqueous drainage. Hence, it is important to find an agent to modulate the wound healing process. This review presents compilation of wound modulation agents that have been tested in vitro, in vivo, or clinically on patients undergoing ocular surgeries, particularly for glaucoma. We identified agents in

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23

Sant’Ana, Monielle, Rafael André da Silva, Luiz Philipe S. Ferreira та ін. "Ac2–26 Hydrogel Modulates IL-1β-Driven Inflammation via Mast Cell-Associated and Immune Regulatory Pathways in Diabetic Wounds". Cells 14, № 13 (2025): 999. https://doi.org/10.3390/cells14130999.

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Chronic, non-resolving inflammation is a major contributor to impaired wound healing in diabetes. Annexin A1 (AnxA1), a pro-resolving mediator, and its mimetic peptide Ac2–26 have demonstrated therapeutic potential in modulating inflammatory responses. In this study, we evaluated the effects of topical Ac2–26 hydrogel in a streptozotocin-induced diabetic wound model. Treatment significantly accelerated wound closure, improved tissue architecture, and reduced leukocyte infiltration. Immunohistochemical analysis revealed diminished mast cell accumulation and IL-1β expression in treated wounds. C

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24

García Coronado, Paola Leonor, Moisés Armides Franco Molina, Diana Ginette Zárate Triviño, Jorge Luis Menchaca Arredondo, Pablo Zapata Benavides, and Cristina Rodriguez Padilla. "Putative Wound Healing Induction Functions of Exosomes Isolated from IMMUNEPOTENT CRP." International Journal of Molecular Sciences 24, no. 10 (2023): 8971. http://dx.doi.org/10.3390/ijms24108971.

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Chronic wounds in diabetic patients can take months or years to heal, representing a great cost for the healthcare sector and impacts on patients’ lifestyles. Therefore, new effective treatment alternatives are needed to accelerate the healing process. Exosomes are nanovesicles involved in the modulation of signaling pathways that can be produced by any cell and can exert functions similar to the cell of origin. For this reason, IMMUNEPOTENT CRP, which is a bovine spleen leukocyte extract, was analyzed to identify the proteins present and is proposed as a source of exosomes. The exosomes were

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25

Zielińska, Małgorzata, Agnieszka Pawłowska, Anna Orzeł, et al. "Wound Microbiota and Its Impact on Wound Healing." International Journal of Molecular Sciences 24, no. 24 (2023): 17318. http://dx.doi.org/10.3390/ijms242417318.

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Wound healing is a complex process influenced by age, systemic conditions, and local factors. The wound microbiota’s crucial role in this process is gaining recognition. This concise review outlines wound microbiota impacts on healing, emphasizing distinct phases like hemostasis, inflammation, and cell proliferation. Inflammatory responses, orchestrated by growth factors and cytokines, recruit neutrophils and monocytes to eliminate pathogens and debris. Notably, microbiota alterations relate to changes in wound healing dynamics. Commensal bacteria influence immune responses, keratinocyte growt

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26

Martin, Josephine L., and Sabita Roy. "Morphine and TAT: Additive modulation of wound healing events (100.15)." Journal of Immunology 178, no. 1_Supplement (2007): S199—S200. http://dx.doi.org/10.4049/jimmunol.178.supp.100.15.

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Abstract Interactions between chronic morphine and the HIV-1 protein TAT are believed to play a major role in accelerating wound pathogenesis of HIV positive patients. Chronic morphine users infected with HIV often display infected and improper wound closure events compared to non-drug abusive HIV populations. Although it is well documented that HIV-1 proteins such as TAT up-regulate chemokine secretion, our laboratory is the first to show morphine suppression of TAT-induced leukocyte migration and chemokine secretion. Simultaneous treatment of morphine and lipopolysaccharide results in altere

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27

Elliott, Stuart. "A clinically effective primary wound dressing that supports self-care for chronic and acute wounds." British Journal of Community Nursing 24, Sup6 (2019): S30—S37. http://dx.doi.org/10.12968/bjcn.2019.24.sup6.s30.

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Wound care forms a large component of the ever-increasing workload of district and community nurses. The need for a cost-effective product that can be used on a variety of wounds and that meets multiple requirements (e.g. protease modulation, anti-microbial, peri-wound skin protection, maceration control and barrier function) is well recognised. The plethora of wound dressings available today all fulfil some, although not all, of these requirements. Choosing the correct dressing decreases healing time, provides cost-effective care and improves patient quality of life. This article looks at the

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28

Petkovic, Marija, Michelle Vang Mouritzen, Biljana Mojsoska, and Håvard Jenssen. "Immunomodulatory Properties of Host Defence Peptides in Skin Wound Healing." Biomolecules 11, no. 7 (2021): 952. http://dx.doi.org/10.3390/biom11070952.

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Cutaneous wound healing is a vital biological process that aids skin regeneration upon injury. Wound healing failure results from persistent inflammatory conditions observed in diabetes, or autoimmune diseases like psoriasis. Chronic wounds are incurable due to factors like poor oxygenation, aberrant function of peripheral sensory nervature, inadequate nutrients and blood tissue supply. The most significant hallmark of chronic wounds is heavily aberrant immune skin function. The immune response in humans relies on a large network of signalling molecules and their interactions. Research studies

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29

Mohite, Popat, Abhijeet Puri, Shubham Munde, et al. "Bioactive Compound-Fortified Nanomedicine in the Modulation of Reactive Oxygen Species and Enhancement of the Wound Healing Process: A Review." Pharmaceutics 17, no. 7 (2025): 855. https://doi.org/10.3390/pharmaceutics17070855.

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Wound healing is a complex biological process that involves the regulation of reactive oxygen species (ROS), which play a critical role in cellular signaling and tissue repair. While the dual nature of ROS means that maintaining controlled levels is essential for effective wound healing, excessive ROS production can hinder the recovery process. Bioactive compounds represent promising therapeutic candidates enriched with polyphenols, which are known for their high therapeutic properties and minimal adverse effects, and are thus highlighted as promising therapeutic candidates for wound healing d

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30

Chang, Jing, and Saeed Rohani. "Edaravone-Delivering PVA-Chitosan Nanofibrous Wound Dressings Promote Diabetic Wound Healing Through Modulation of Oxidative Stress and Inflammation." Journal of Biomedical Nanotechnology 19, no. 4 (2023): 624–31. http://dx.doi.org/10.1166/jbn.2023.3561.

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In the current study, edaravone was loaded into electrospun PVA/chitosan wound dressings to develop a potential wound care material for diabetic wounds. Different in vitro studies were performed to characterize the dressings. In vivo study was carried out in a rat model of diabetic wound healing. Study showed that the nanofibrous membranes prevented bacterial penetration and showed no toxicity toward skin fibroblast cells. In vivo study showed that edaravone-loaded wound dressings had the highest rate of wound closure and formation of new epithelium compared with other groups. Gene expression

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31

Ahsanu Taqwim Hidayat та Parish Budiono. "Ozonated Aloe Vera: A Novel Topical Agent for Improved Wound Healing and Reduced Scar Formation on TGF-β Modulation Invivo Study". Bioscientia Medicina : Journal of Biomedicine and Translational Research 9, № 1 (2024): 5854–66. http://dx.doi.org/10.37275/bsm.v9i1.1159.

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Background: Chronic wounds and impaired wound healing represent a significant healthcare burden. Aloe vera has been recognized for its therapeutic potential in wound healing, and the combination with ozone, and ozonated aloe vera, may offer synergistic effects. This study investigated the effects of ozonated aloe vera oil on wound healing and scar formation, focusing on TGF-β modulation in a rat model. Methods: Full-thickness skin defects were created on 50 Sprague Dawley rats, which were randomly divided into five groups: (1) control (untreated), (2) aloe vera oil, (3) ozonated aloe vera oil

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32

Jordan, J. F. "Photodynamic modulation of wound healing in glaucoma filtration surgery." British Journal of Ophthalmology 87, no. 7 (2003): 870–75. http://dx.doi.org/10.1136/bjo.87.7.870.

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33

Khaw, Peng T., and C. S. Migdal. "Current techniques in wound healing modulation in glaucoma surgery." Current Opinion in Ophthalmology 7, no. 2 (1996): 24–33. http://dx.doi.org/10.1097/00055735-199604000-00005.

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34

Oryan, A., A. Tabatabaei Naeini, A. Moshiri, A. Mohammadalipour, and M. R. Tabandeh. "Modulation of cutaneous wound healing by silymarin in rats." Journal of Wound Care 21, no. 9 (2012): 457–64. http://dx.doi.org/10.12968/jowc.2012.21.9.457.

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35

Mustoe, Thomas A., and Beatriz H. Porras-Reyes. "Modulation Of Wound Healing Response In Chronic Irradiated Tissues." Clinics in Plastic Surgery 20, no. 3 (1993): 465–72. http://dx.doi.org/10.1016/s0094-1298(20)31189-5.

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36

Sturm, A. "Modulation of gastrointestinal wound repair and inflammation by phospholipids." Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1582, no. 1-3 (2002): 282–88. http://dx.doi.org/10.1016/s1388-1981(02)00182-8.

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37

Savage, J. D. "Modulation of wound healing response in chronic irradiated tissues." Journal of Oral and Maxillofacial Surgery 52, no. 3 (1994): 336. http://dx.doi.org/10.1016/0278-2391(94)90325-5.

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38

Lo, Joe F., Martin Brennan, Zameer Merchant, et al. "Microfluidic wound bandage: Localized oxygen modulation of collagen maturation." Wound Repair and Regeneration 21, no. 2 (2013): 226–34. http://dx.doi.org/10.1111/wrr.12021.

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39

Bartold, P. Mark, and A. Raben. "Growth factor modulation of fibroblasts in simulated wound healing." Journal of Periodontal Research 31, no. 3 (1996): 205–16. http://dx.doi.org/10.1111/j.1600-0765.1996.tb00485.x.

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40

Machfira, Bulantrisna, and Fawzy Ahmad. "The Negative Impact of Vaping and Electric Cigarettes for Healing of Acute Wounds: A Literature Review." International Journal of Medical Science and Clinical Research Studies 04, no. 05 (2024): 940–45. https://doi.org/10.5281/zenodo.11258734.

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Emerging evidence suggests that vaping can significantly impede wound healing, with prevalence rates of current e-cigarette use varying between 3.3% and 11.8%. This study aims to investigate the impact of vaping on wound healing, particularly in acute wounds encountered in plastic surgery settings. Electronic cigarettes (e-cigarettes), comprising a rechargeable battery and an atomizer or heating element, typically contain flavored liquids with or without nicotine as humectants. Skin wounds heal through overlapping inflammatory, proliferative, and remodeling phases. Chemical constituents of e-c

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41

Banerjee, Jaideep, Yuk Cheung Chan, and Chandan K. Sen. "MicroRNAs in skin and wound healing." Physiological Genomics 43, no. 10 (2011): 543–56. http://dx.doi.org/10.1152/physiolgenomics.00157.2010.

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MicroRNAs (miRNAs) are small endogenous RNA molecules ∼22 nt in length. miRNAs are capable of posttranscriptional gene regulation by binding to their target messenger RNAs (mRNAs), leading to mRNA degradation or suppression of translation. miRNAs have recently been shown to play pivotal roles in skin development and are linked to various skin pathologies, cancer, and wound healing. This review focuses on the role of miRNAs in cutaneous biology, the various methods of miRNA modulation, and the therapeutic opportunities in treatment of skin diseases and wound healing.

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42

Cao, Yuqi, Jiagui Sun, Shengao Qin, Zhengshu Zhou, Yanan Xu, and Chenggang Liu. "Advances and Challenges in Immune-Modulatory Biomaterials for Wound Healing Applications." Pharmaceutics 16, no. 8 (2024): 990. http://dx.doi.org/10.3390/pharmaceutics16080990.

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Wound healing progresses through three distinct stages: inflammation, proliferation, and remodeling. Immune regulation is a central component throughout, crucial for orchestrating inflammatory responses, facilitating tissue repair, and restraining scar tissue formation. Elements such as mitochondria, reactive oxygen species (ROS), macrophages, autophagy, ferroptosis, and cytokines collaboratively shape immune regulation in this healing process. Skin wound dressings, recognized for their ability to augment biomaterials’ immunomodulatory characteristics via antimicrobial, antioxidative, pro- or

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43

Kempuraj, Duraisamy, and Rajiv R. Mohan. "Autophagy in Extracellular Matrix and Wound Healing Modulation in the Cornea." Biomedicines 10, no. 2 (2022): 339. http://dx.doi.org/10.3390/biomedicines10020339.

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Autophagy is a robust cellular mechanism for disposing of harmful molecules or recycling them to cells, which also regulates physiopathological processes in cornea. Dysregulated autophagy causes inefficient clearance of unwanted proteins and cellular debris, mitochondrial disorganization, defective inflammation, organ dysfunctions, cell death, and diseases. The cornea accounts for two-thirds of the refraction of light that occurs in the eyes, but is prone to trauma/injury and infection. The extracellular matrix (ECM) is a noncellular dynamic macromolecular network in corneal tissues comprised

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44

Ammassam Veettil, Remya, Daniela C. Marcano, Xiaoyong Yuan, et al. "Dextran Sulfate Polymer Wafer Promotes Corneal Wound Healing." Pharmaceutics 13, no. 10 (2021): 1628. http://dx.doi.org/10.3390/pharmaceutics13101628.

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Eye injuries due to corneal abrasions, chemical spills, penetrating wounds, and microbial infections cause corneal scarring and opacification that result in impaired vision or blindness. However, presently available eye drop formulations of anti-inflammatory and antibiotic drugs are not effective due to their rapid clearance from the ocular surface or due to drug-related side effects such as cataract formation or increased intraocular pressure. In this article, we presented the development of a dextran sulfate-based polymer wafer (DS-wafer) for the effective modulation of inflammation and fibr

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45

Krzyszczyk, Paulina, Kishan Patel, Yixin Meng, et al. "Macrophage modulation by polymerized hemoglobins: Potential as a wound-healing therapy." TECHNOLOGY 07, no. 03n04 (2019): 84–97. http://dx.doi.org/10.1142/s2339547819500055.

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Chronic skin wounds are hypoxic and are stalled in a pro-inflammatory state. Hemoglobin (Hb)-based oxygen carriers have shown potential in increasing oxygen delivery to aid wound healing. Macrophages also take up Hb, thus altering their phenotype and the regulation of inflammation. Herein, we compared the effect of Hb and polymerized Hbs (PolyHbs) on the phenotype of human macrophages. Macrophages were incubated with Hb or different forms of PolyHbs, and the inflammatory secretion profile was analyzed. PolyHbs were produced by polymerizing Hb in the relaxed (R) or tense (T) quaternary state an

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46

Beegum, Fathima, Anuranjana P V, Krupa thankam George, et al. "Investigating the role of sesamol in promoting the healing of diabetic wounds by analyzing molecular expression patterns in human diabetic dermal fibroblasts." Journal of Applied Pharmaceutical Research 12, no. 3 (2024): 107–18. http://dx.doi.org/10.69857/joapr.v12i3.505.

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Background: Sesamol (3,4-methylenedioxyphenol) is one of the plant compounds tested in vivo for diabetic wound healing, normal wound healing, and dexamethasone-induced delayed wound healing. Elucidation of mechanisms underlying the wound healing effect of sesamol through modulation of various molecular and cellular pathways is the crux of this paper. Objectives: The objective of the current work was to uncover the mechanism of sesamol underlying the treatment of diabetic wounds using gene expression analysis. Methods: The cytotoxicity assay was performed using an SRB colorimetric assay, from w

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47

Ye, Haifeng, and Yuval Rinkevich. "Fascia Layer—A Novel Target for the Application of Biomaterials in Skin Wound Healing." International Journal of Molecular Sciences 24, no. 3 (2023): 2936. http://dx.doi.org/10.3390/ijms24032936.

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As the first barrier of the human body, the skin has been of great concern for its wound healing and regeneration. The healing of large, refractory wounds is difficult to be repaired by cell proliferation at the wound edges and usually requires manual intervention for treatment. Therefore, therapeutic tools such as stem cells, biomaterials, and cytokines have been applied to the treatment of skin wounds. Skin microenvironment modulation is a key technology to promote wound repair and skin regeneration. In recent years, a series of novel bioactive materials that modulate the microenvironment an

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48

He, Tao, Yuzhen Xiao, Zhijun Guo, et al. "Modulation of Macrophage Function by Bioactive Wound Dressings with an Emphasis on Extracellular Matrix-Based Scaffolds and Nanofibrous Composites." Pharmaceutics 15, no. 3 (2023): 794. http://dx.doi.org/10.3390/pharmaceutics15030794.

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Bioactive wound dressings that are capable of regulating the local wound microenvironment have attracted a very large interest in the field of regenerative medicine. Macrophages have many critical roles in normal wound healing, and the dysfunction of macrophages significantly contributes to impaired or non-healing skin wounds. Regulation of macrophage polarization towards an M2 phenotype provides a feasible strategy to enhance chronic wound healing, mainly by promoting the transition of chronic inflammation to the proliferation phase of wound healing, upregulating the level of anti-inflammator

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49

Obeagu, Emmanuel Ifeanyi. "Improved Wound Healing: The Healing Power of Blood Transfusions for Individuals with HIV." International Journal of Medical Sciences and Pharma Research 10, no. 3 (2024): 16–22. http://dx.doi.org/10.22270/ijmspr.v10i3.107.

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Wound healing in individuals with HIV is often compromised due to impaired immune function, chronic inflammation, and common comorbidities like anemia. Blood transfusions, traditionally used to manage anemia, have shown promise in enhancing wound healing through multiple mechanisms. This review explores the role of blood transfusions in improving wound healing for HIV-positive patients, focusing on their impact on oxygen delivery, immune modulation, inflammation reduction, and tissue repair. By restoring adequate hemoglobin levels, blood transfusions can improve oxygenation, support cellular m

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50

Healy, Catherine R., Georgina Gethin, Abhay Pandit, and David P. Finn. "Chronic wound-related pain, wound healing and the therapeutic potential of cannabinoids and endocannabinoid system modulation." Biomedicine & Pharmacotherapy 168 (December 2023): 115714. http://dx.doi.org/10.1016/j.biopha.2023.115714.

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