Academic literature on the topic 'Young and old mice'

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Journal articles on the topic "Young and old mice"

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Le Bras, Alexandra. "Old blood for young mice." Lab Animal 51, no. 9 (2022): 238. http://dx.doi.org/10.1038/s41684-022-01044-6.

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Le Bras, Alexandra. "Young blood for old mice." Lab Animal 48, no. 4 (2019): 113. http://dx.doi.org/10.1038/s41684-019-0280-3.

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Lynch, G. S., J. A. Rafael, R. T. Hinkle, N. M. Cole, J. S. Chamberlain, and J. A. Faulkner. "Contractile properties of diaphragm muscle segments from old mdx and old transgenic mdx mice." American Journal of Physiology-Cell Physiology 272, no. 6 (1997): C2063—C2068. http://dx.doi.org/10.1152/ajpcell.1997.272.6.c2063.

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Diaphragm muscles of young (4- to 6-mo-old) mdx mice show severe fiber necrosis and have normalized forces and powers 60 and 46% of the values for control C57BL/10 mice. In contrast, microinjection of mdx mouse embryos with a truncated dystrophin minigene has produced young transgenic mdx (tg-mdx) mice with a level of dystrophin expression and structural and functional properties of diaphragm muscle strips measured in vitro not different from those of control mice. Whether dystrophin expression and functional corrections persist for the life span of these animals is not know. We tested the nul
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Dalmer, Antonia, Paul Wörner, Mathias Manzke, et al. "Comparison of Myocardial Function in Young and Old Mice During Acute Myocardial Infarction: A Cardiac Magnetic Resonance Study." Diagnostics 15, no. 12 (2025): 1447. https://doi.org/10.3390/diagnostics15121447.

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Background/Objectives: This study aimed to compare changes in functional and strain parameters in young and old mice using cardiac MRI before and shortly after myocardial infarction. Methods: In this prospective experimental study, 7 young mice and 10 old mice underwent a cardiac MRI 5 days before and 2 days after myocardial infarction by LAD ligation. Functional parameters such as EDV, ESV, EF, SV, and Strain were determined. Results: EDV in the young mice before LAD ligation was significantly lower than in the old mice (p-value 0.002). EDV significantly increased after infarction in both gro
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M Gbaj, Abdul, Emhemmed Ali Elgallal, Inass A Sadawe, et al. "Immunogenicity and Safety of Sinopharm Covid-19 Vaccine in Young Mice." International Journal of Clinical Case Reports and Reviews 10, no. 3 (2022): 01–03. http://dx.doi.org/10.31579/2690-4861/185.

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Background and Aim: Vaccines to prevent SARS-CoV-2 infection may be considered a promising way for reduction of the pandemic. Many different vaccines have become obtainable for use in many countries. The present study aims to evaluate the immune response and the safety of Sinopharm COVID-19 vaccine on 14 days old mice. Materials and Methods:Our experimental study was performed on two weeks old mice, selected by random allocation. The mice were divided into three groups of 12. Group one received asingle dose of 0.5 ml Sinopharm COVID-19 vaccine, group two received two doses of 0.5 ml Sinopharm
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Zhou, T., C. K. Edwards, and J. D. Mountz. "Prevention of age-related T cell apoptosis defect in CD2-fas-transgenic mice." Journal of Experimental Medicine 182, no. 1 (1995): 129–37. http://dx.doi.org/10.1084/jem.182.1.129.

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T cell dysfunction and thymic involution are major immunologic abnormalities associated with aging. Fas (CD95) is a bifunctional molecule that is critical for apoptosis and stimulation during T cell development, but the role of Fas during aging has not been determined. Fas expression and function on T cells from old (22-26-mo-old) mice was compared with young (2-mo-old) mice and old CD2-fas-transgenic mice. Fas expression and ligand-induced apoptosis were decreased on T cells from old mice compared with young mice. This correlated with an age-related increase in CD44+Fas- T cells. There was a
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Løvik, M., and R. J. North. "Effect of aging on antimicrobial immunity: old mice display a normal capacity for generating protective T cells and immunologic memory in response to infection with Listeria monocytogenes." Journal of Immunology 135, no. 5 (1985): 3479–86. http://dx.doi.org/10.4049/jimmunol.135.5.3479.

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Abstract Old (19 to 30 mo) and young adult (11 to 16 wk) AB6F1 mice of both sexes were compared in terms of their capacity to resist infection with Listeria monocytogenes. The LD50 was found to be two to four times higher for old than for young mice, and the time to death was longer for old mice. Enumeration of bacteria in the livers and spleens showed that old mice restricted growth of Listeria more effectively than young mice during the preimmune phase of infection, the difference being detectable as early as 12 to 24 hr after bacterial inoculation. Therefore, to ensure a similar level of in
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Wu, Dayong, Casilda Mura, Alison A. Beharka, et al. "Age-associated increase in PGE2 synthesis and COX activity in murine macrophages is reversed by vitamin E." American Journal of Physiology-Cell Physiology 275, no. 3 (1998): C661—C668. http://dx.doi.org/10.1152/ajpcell.1998.275.3.c661.

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We previously showed that increased macrophage and PGE2 production with age is due to enhanced cyclooxygenase (COX) activity and COX-2 expression. This study determined the effect of vitamin E supplementation on macrophage PGE2 synthesis in young and old mice and its underlying mechanism. Mice were fed 30 or 500 parts per million vitamin E for 30 days. Lipopolysaccharide (LPS)-stimulated macrophages from old mice produced significantly more PGE2 than those from young mice. Vitamin E supplementation reversed the increased PGE2 production in old mice but had no effect on macrophage PGE2productio
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Erzar, Eva, Mojca Kerec Kos, Katja Lakota, Peter Veranič, and Andreja Erman. "Does the Urothelium of Old Mice Regenerate after Chitosan Injury as Quickly as the Urothelium of Young Mice?" International Journal of Molecular Sciences 21, no. 10 (2020): 3502. http://dx.doi.org/10.3390/ijms21103502.

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The aging of organisms leads to a decreased ability of tissue to regenerate after injury. The regeneration of the bladder urothelium after induced desquamation with biopolymer chitosan has been studied in young mice but not in old mice. Chitosan is a suitable inducer of urothelial desquamation because it is known to be non-toxic. We used chitosan for desquamation of urothelial cells in order to compare the dynamics of urothelial regeneration after injury between young and old mice. Our aim was to determine whether the urothelial function and structure of old mice is restored as fast as in youn
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Tripathi, Deepak, Elwyn Welch, Satyanarayana Swamy Cheekatla та ін. "ALCOHOL ENHANCES TYPE 1 INTERFERON-α AND MORTALITY OF YOUNG MICE INFECTED WITH Mycobacterium tuberculosis". Journal of Immunology 200, № 1_Supplement (2018): 114.14. http://dx.doi.org/10.4049/jimmunol.200.supp.114.14.

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Abstract In the current study, we determined the effects of chronic alcohol consumption on the mortality of young and old mice and immune responses during Mycobacterium tuberculosis (Mtb) infection. Eighty percent of Mtb H37Rv infected alcohol-fed young mice died in five months compared to twenty-five percent in Mtb infected alcohol-fed old mice. There is no significant difference in lung bacterial burden of control and alcohol diet fed young and old mice. IFN-α levels were significantly higher in the lungs of Mtb infected alcohol-fed young mice and treatment with anti-IFNAR-1 antibody enhance
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Dissertations / Theses on the topic "Young and old mice"

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Wu, Xianai. "Deoxynivalenol alters circulating and splenic leukocyte and cell migration markers in interaction with time course and sex in young and old BALB /c mice." [Ames, Iowa : Iowa State University], 2008.

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Attoh, mensah Kouakou. "Risques de chutes et de troubles cognitifs consécutifs à la consommation de certains médicaments chez les seniors : approche translationnelle Psychotropic Polypharmacy in Adults 55 Years or Older: A Risk for Impaired Global Cognition, Executive Function, and Mobility Adverse Effects of Anticholinergic Drugs on Cognition and Mobility: Cutoff for Impairment in a Cross-Sectional Study in Young-Old and Old-Old Adults : Chronic tramadol administration impairs reversal learning in a touchscreen-based visual discrimination task in mice." Thesis, Normandie, 2020. http://www.theses.fr/2020NORMC427.

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Les psychotropes et les médicaments à propriétés anticholinergiques (anti-muscariniques) ont été associés aux risques de chute et de troubles cognitifs chez les séniors. Nos travaux avaient pour but de mieux comprendre le rôle de ces médicaments dans les phénomènes de troubles de la mobilité et de troubles cognitifs. Dans un premier temps, nous avons montré que la consommation de 2 psychotropes ou plus par jour et/ou d’1 seul médicament à propriétés anticholinergiques par jour, dès la charge anticholinergique minimale, est associée à un déficit lors de tests d’évaluation de la marche et de la
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Rottinghaus, Erin Kay. "Pulmonary Innate Immune Mechanisms in Old Mice." The Ohio State University, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=osu1237473771.

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TORRINI, IRENE. "Healthcare Expenditures for the Young-Old Population." Doctoral thesis, Università degli Studi di Milano-Bicocca, 2021. http://hdl.handle.net/10281/330206.

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In questa tesi modelliamo l'evoluzione nel ciclo di vita delle spese sanitarie individuali (HCE), espresse in funzione del processo di invecchiamento, degli shock e delle condizioni di salute e della distanza dalla morte. Tutte le analisi sono condotte utilizzando un unico dataset, che permette di analizzare diversi tipi di servizi sanitari e diversi sottocampioni di individui. La popolazione di interesse è costituita da individui di età compresa tra i 50 e i 70 anni, la finestra di età in cui si verificano i primi eventi sanitari avversi. Nel primo capitolo, usiamo un two-way fixed effects m
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Rieckmann, Nina. "Adaptation and resilience in middle-aged, young old, and old cataract patients." [S.l.] : [s.n.], 2003. http://www.diss.fu-berlin.de/2003/225/index.html.

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Hernandez, Silvia C. "Suicide Among Young-Old And Old-Old Adults: Interactions Between Age, Social Isolation, And Physical Illness." Case Western Reserve University School of Graduate Studies / OhioLINK, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=case1544205405031949.

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Menz, Hylton Physiology UNSW. "Walking stability in young, old and neuropathic subjects." Awarded by:University of New South Wales. Physiology, 2002. http://handle.unsw.edu.au/1959.4/18637.

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This thesis investigates walking patterns in healthy young people and in people with an increased risk of falling, and determines the physiological contributions to walking stability. First, a review of the relevant literature on techniques for assessing walking stability, age-related changes in balance and gait, and the contributions of vision, vestibular function, peripheral sensation and strength was undertaken. In response to a critical analysis of these findings, a new technique and protocol for the assessment of walking stability was developed. This involved measuring and analysing head
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Forbes, Dorothy Anne. "Canadian community-dwelling young-old and old-old, psychosocial determinants of health status and satisfaction with health care." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk2/tape17/PQDD_0027/NQ34762.pdf.

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Piasecki, Matthew John. "Motor unit characteristics in young and old skeletal muscle." Thesis, Manchester Metropolitan University, 2015. http://e-space.mmu.ac.uk/595500/.

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The neuromuscular changes associated with increasing age include a reduction in the number of motor units (MU) and an increase in the size of those that remain. Electromyography (EMG) has been used to investigate these changes, however the available literature is largely concerned with small peripheral muscles and little is known of the large leg muscles, in particular the vastus lateralis (VL) which is particularly susceptible to age-related atrophy. In Chapter 2 we highlight the variations in MU structure across a single large muscle, the VL. Motor unit properties differed according to locat
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Capper, Alyssa Lynn. "Size-Weight Scaling in Healthy Young and Old Adults." Thesis, University of Iowa, 2013. https://ir.uiowa.edu/etd/4826.

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Visual analysis of an object's size can be used to determine the lifting forces we program to lift the object so that the resulting movements achieve the goals of the lift. These forces are scaled or specified prior to the object moving, that is, before sensory feedback information about the object's weight is available. Sensorimotor memories are relied on to provide relevant information about an object's density and weight if the object was previously manipulated. It is well established that young adults accurately scale
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Books on the topic "Young and old mice"

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Health Effects Institute. Health Review Committee. Pulmonary effects of inhaled diesel exhaust in young and old mice: A pilot project. Health Effects Institute, 2010.

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Dawson, Emily C. Young and old. Amicus, 2011.

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Morss, Ben. Cinderella's mice: A musical for young audiences. Baker's Plays, 2009.

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London, Jonathan. Old salt, young salt. Lothrop, Lee & Shepard Books, 1997.

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London, Jonathan. Old salt, young salt. Lothrop, Lee & Shepard Books, 1996.

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Brubeck, Dave. Young lions & old tigers. Telarc Jazz, 1995.

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Kean, Abram. Old and young ahead. Flanker Press, 2000.

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Carol, Seefeldt, and National Association for the Education of Young Children., eds. Young and old together. National Association for the Education of Young Children, 1990.

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Wagner, Christian C. The young old masters: A spiritual guide for young and old. OME Press, 1998.

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Michael, Rosen. A cat and mouse story: An old tale. Scholastic Publications, 1985.

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Book chapters on the topic "Young and old mice"

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Meydani, Simin Nikbin, Edgar S. Cathcart, Robert E. Hopkins, Mohsen Meydani, Kenneth C. Hayes, and Jeffry B. Blumberg. "Antioxidants in Experimental Amyloidosis of Young and Old Mice." In Amyloidosis. Springer US, 1986. http://dx.doi.org/10.1007/978-1-4613-2199-6_87.

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Bourus, Terri. "How Old Is Young?" In Young Shakespeare’s Young Hamlet. Palgrave Macmillan US, 2014. http://dx.doi.org/10.1057/9781137465641_5.

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Mittemeijer, Eric J. "“Young” Versus “Old”." In How Science Runs. Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-90095-3_9.

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Devonis, David C. "Young and Old." In Exploring Cross-Cultural Psychology, 2nd ed. Routledge, 2023. http://dx.doi.org/10.4324/9781003300380-55.

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Britton, Derek. "‘The Old, Young Insouciance’." In Lady Chatterley. Routledge, 2023. http://dx.doi.org/10.4324/9781003379744-2.

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Grumbine, R. Edward. "Old Mountains, Young Parks." In Where the Dragon Meets the Angry River. Island Press/Center for Resource Economics, 2010. http://dx.doi.org/10.5822/978-1-59726-811-0_4.

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Farley, Caroline. "Never too old." In Young Children and Their Communities. Routledge, 2018. http://dx.doi.org/10.4324/9781315151342-6.

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Fabry, Götz. "Young Boy meets Old Girl." In Wilde Erdbeeren auf Wolke Neun. Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-662-50488-8_18.

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Shattock, Joanne, Elisabeth Jay, and Valerie Sanders. "The Young and the Old." In The Selected Works of Margaret Oliphant, Part V Volume 20. Routledge, 2024. http://dx.doi.org/10.4324/9781003554141-19.

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Russell, Bertrand. "VIII. Old and Young Cultures." In Fact and Fiction. Routledge, 2024. http://dx.doi.org/10.4324/9781003572152-16.

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Conference papers on the topic "Young and old mice"

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van Otterdijk, Marieke, Dongho Kwak, Adel Baselizadeh, Diana Saplacan Lindblom, and Jim Torresen. "Age-Old Gesture: Analyzing the Intuitive Responses to Robot Handshakes Among Seniors and Young Adults." In 2024 33rd IEEE International Conference on Robot and Human Interactive Communication (ROMAN). IEEE, 2024. http://dx.doi.org/10.1109/ro-man60168.2024.10731393.

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VUOTTO, ML, MTL IELPO, R. MIRANDA, et al. "PHAGOCYTE ACTIVITY IN OLD AND YOUNG MICE UNDERGOING SURGICAL STRESS." In Proceedings of the 11th International Symposium. WORLD SCIENTIFIC, 2001. http://dx.doi.org/10.1142/9789812811158_0106.

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Moeini, Mohammad, Maryam S. Tabatabaei, Samuel Bélanger, et al. "Effects of anesthesia on the cerebral capillary blood flow in young and old mice." In SPIE BiOS, edited by Ammasi Periasamy, Peter T. C. So, and Karsten König. SPIE, 2015. http://dx.doi.org/10.1117/12.2079803.

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Khalyfa, A., and D. Gozal. "Multi-omics Analysis of Luminal Exosomes in Young and Old Male and Female Mice." In American Thoracic Society 2024 International Conference, May 17-22, 2024 - San Diego, CA. American Thoracic Society, 2024. http://dx.doi.org/10.1164/ajrccm-conference.2024.209.1_meetingabstracts.a2664.

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Moskaleva, Elizaveta, Alla Rodina, Yulia Semochkina, Olga Vysotskaya, Anastasia Romantsova та Aleksei Degtyarev. "MICROGLIA IN YOUNG AND OLD MICE АND IN THE LATE PERIOD AFTER GAMMA-NEUTRON IRRADIATION". У XVII INTERNATIONAL INTERDISCIPLINARY CONGRESS NEUROSCIENCE FOR MEDICINE AND PSYCHOLOGY. LCC MAKS Press, 2021. http://dx.doi.org/10.29003/m2239.sudak.ns2021-17/267-268.

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Zhu, Hui, Jessica Shih, David S. Long, John R. Hagaman, Nobuyo Maeda, and Morton H. Friedman. "Different Strains of Mice Exhibit Different Aortic Arch Geometry and Plaque Distribution: A Fluid Dynamic Effect." In ASME 2007 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2007. http://dx.doi.org/10.1115/sbc2007-175844.

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In earlier work, we observed different patterns of disease distribution in the aortic arches of apolipoprotien E (apoE)-deficient C57BL/6 (B6) and 129/SvEv (129) mouse strains [1]. In the relatively young mice (6 mo old), fatty plaques are seen mainly in the aortic root area, extending into the right innominate artery (RIA), with very little plaque in the more distal aortic arch in the B6 strain. However, in the 129 strain, plaques are found more in the inner curvature of the aortic arch but less in the sinus area than in B6 strain (Fig. 1).
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Klee, Stephan, Daniel Veyel, Karsten Quast, et al. "Because age matters – A comparative multi-omics analysis of young and old mice in the Bleomycin-induced lung fibrosis model." In Abstracts from the 17th ERS Lung Science Conference: ‘Mechanisms of Acute Exacerbation of Respiratory Disease’. European Respiratory Society, 2019. http://dx.doi.org/10.1183/23120541.lungscienceconference-2019.pp113.

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Espinosa, Gabriela, Lisa Bennett, William Gardner, and Jessica Wagenseil. "The Effects of Extracellular Matrix Protein Insufficiency and Treatment on the Stiffness of Arterial Smooth Muscle Cells." In ASME 2013 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/sbc2013-14131.

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Increased arterial stiffness is directly correlated with hypertension and cardiovascular disease. Stiffness of the conducting arteries is largely determined by the extracellular matrix (ECM) proteins in the wall, such as collagen and elastin, produced by the smooth muscle cells (SMCs) found in the medial layer. Elastin is deposited as soluble tropoelastin and is later crosslinked into elastin fibers. Newborn mice lacking the elastin protein ( Eln−/−) have increased arterial wall stiffness and SMCs with altered proliferation, migration and morphology [1]. Vessel elasticity is also mediated by o
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Xu, Xuexin, Yin-Leng Theng, Jinhui Li, and Pham Tan Phat. "Investigating Effects of Exergames on Exercise Intentions among Young-Old and Old-Old." In CHI'16: CHI Conference on Human Factors in Computing Systems. ACM, 2016. http://dx.doi.org/10.1145/2851581.2892296.

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Stahl, Ingolf, Richard G. Born, James O. Henriksen, and Henry Herper. "GPSS 50 years old, but still young." In 2011 Winter Simulation Conference - (WSC 2011). IEEE, 2011. http://dx.doi.org/10.1109/wsc.2011.6148085.

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Reports on the topic "Young and old mice"

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Alesina, Alberto, Ugo Troiano, and Traviss Cassidy. Old and Young Politicians. National Bureau of Economic Research, 2015. http://dx.doi.org/10.3386/w20977.

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Ma, Song, Justin Murfin, and Ryan Pratt. Young Firms, Old Capital. National Bureau of Economic Research, 2021. http://dx.doi.org/10.3386/w29189.

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Kremer, Michael, and Jim Thomson. Young Workers, Old Workers, and Convergence. National Bureau of Economic Research, 1994. http://dx.doi.org/10.3386/w4827.

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Owens, Greg D., Nafisa M. Jadavji, and Patrice D. Smith. Neurogenesis Unchanged by MTHFR Deficiency in Three-Week-Old Mice. Journal of Young Investigators, 2016. http://dx.doi.org/10.22186/jyi.31.6.39-43.

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Campbell, Jeffrey, and Jonas D. M. Fisher. Organizational Flexibility and Employment Dynamics at Young and Old Plants. National Bureau of Economic Research, 1998. http://dx.doi.org/10.3386/w6809.

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Johnson, Paul. How can we level the playing field between young and old? The IFS, 2017. http://dx.doi.org/10.1920/co.ifs.2024.0714.

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Cutler, David, and Ellen Meara. The Medical Costs of The Young and Old: A Forty Year Perspective. National Bureau of Economic Research, 1997. http://dx.doi.org/10.3386/w6114.

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Jaimovich, Nir, and Henry Siu. The Young, the Old, and the Restless: Demographics and Business Cycle Volatility. National Bureau of Economic Research, 2008. http://dx.doi.org/10.3386/w14063.

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Razin, Assaf, and Efraim Sadka. Aging and the Welfare State: The Role of Young and Old Voting Pivots. National Bureau of Economic Research, 2004. http://dx.doi.org/10.3386/w10967.

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Siemens, Penni. A Comparison of the Cohesion in the Expository Discourse of the Optimally-Healthy Young-Old and the Optimally-Healthy Oldest-Old. Portland State University Library, 2000. http://dx.doi.org/10.15760/etd.6665.

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