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Dissertations / Theses on the topic 'Young and old mice'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

Wu, Xianai. "Deoxynivalenol alters circulating and splenic leukocyte and cell migration markers in interaction with time course and sex in young and old BALB /c mice." [Ames, Iowa : Iowa State University], 2008.

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2

Attoh, mensah Kouakou. "Risques de chutes et de troubles cognitifs consécutifs à la consommation de certains médicaments chez les seniors : approche translationnelle Psychotropic Polypharmacy in Adults 55 Years or Older: A Risk for Impaired Global Cognition, Executive Function, and Mobility Adverse Effects of Anticholinergic Drugs on Cognition and Mobility: Cutoff for Impairment in a Cross-Sectional Study in Young-Old and Old-Old Adults : Chronic tramadol administration impairs reversal learning in a touchscreen-based visual discrimination task in mice." Thesis, Normandie, 2020. http://www.theses.fr/2020NORMC427.

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Les psychotropes et les médicaments à propriétés anticholinergiques (anti-muscariniques) ont été associés aux risques de chute et de troubles cognitifs chez les séniors. Nos travaux avaient pour but de mieux comprendre le rôle de ces médicaments dans les phénomènes de troubles de la mobilité et de troubles cognitifs. Dans un premier temps, nous avons montré que la consommation de 2 psychotropes ou plus par jour et/ou d’1 seul médicament à propriétés anticholinergiques par jour, dès la charge anticholinergique minimale, est associée à un déficit lors de tests d’évaluation de la marche et de la

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3

Rottinghaus, Erin Kay. "Pulmonary Innate Immune Mechanisms in Old Mice." The Ohio State University, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=osu1237473771.

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4

TORRINI, IRENE. "Healthcare Expenditures for the Young-Old Population." Doctoral thesis, Università degli Studi di Milano-Bicocca, 2021. http://hdl.handle.net/10281/330206.

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In questa tesi modelliamo l'evoluzione nel ciclo di vita delle spese sanitarie individuali (HCE), espresse in funzione del processo di invecchiamento, degli shock e delle condizioni di salute e della distanza dalla morte. Tutte le analisi sono condotte utilizzando un unico dataset, che permette di analizzare diversi tipi di servizi sanitari e diversi sottocampioni di individui. La popolazione di interesse è costituita da individui di età compresa tra i 50 e i 70 anni, la finestra di età in cui si verificano i primi eventi sanitari avversi. Nel primo capitolo, usiamo un two-way fixed effects m

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5

Rieckmann, Nina. "Adaptation and resilience in middle-aged, young old, and old cataract patients." [S.l.] : [s.n.], 2003. http://www.diss.fu-berlin.de/2003/225/index.html.

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6

Hernandez, Silvia C. "Suicide Among Young-Old And Old-Old Adults: Interactions Between Age, Social Isolation, And Physical Illness." Case Western Reserve University School of Graduate Studies / OhioLINK, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=case1544205405031949.

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7

Menz, Hylton Physiology UNSW. "Walking stability in young, old and neuropathic subjects." Awarded by:University of New South Wales. Physiology, 2002. http://handle.unsw.edu.au/1959.4/18637.

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This thesis investigates walking patterns in healthy young people and in people with an increased risk of falling, and determines the physiological contributions to walking stability. First, a review of the relevant literature on techniques for assessing walking stability, age-related changes in balance and gait, and the contributions of vision, vestibular function, peripheral sensation and strength was undertaken. In response to a critical analysis of these findings, a new technique and protocol for the assessment of walking stability was developed. This involved measuring and analysing head

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8

Forbes, Dorothy Anne. "Canadian community-dwelling young-old and old-old, psychosocial determinants of health status and satisfaction with health care." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk2/tape17/PQDD_0027/NQ34762.pdf.

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9

Piasecki, Matthew John. "Motor unit characteristics in young and old skeletal muscle." Thesis, Manchester Metropolitan University, 2015. http://e-space.mmu.ac.uk/595500/.

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The neuromuscular changes associated with increasing age include a reduction in the number of motor units (MU) and an increase in the size of those that remain. Electromyography (EMG) has been used to investigate these changes, however the available literature is largely concerned with small peripheral muscles and little is known of the large leg muscles, in particular the vastus lateralis (VL) which is particularly susceptible to age-related atrophy. In Chapter 2 we highlight the variations in MU structure across a single large muscle, the VL. Motor unit properties differed according to locat

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10

Capper, Alyssa Lynn. "Size-Weight Scaling in Healthy Young and Old Adults." Thesis, University of Iowa, 2013. https://ir.uiowa.edu/etd/4826.

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Visual analysis of an object's size can be used to determine the lifting forces we program to lift the object so that the resulting movements achieve the goals of the lift. These forces are scaled or specified prior to the object moving, that is, before sensory feedback information about the object's weight is available. Sensorimotor memories are relied on to provide relevant information about an object's density and weight if the object was previously manipulated. It is well established that young adults accurately scale

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11

Lai, Yeuk-yu. "Characterization of lymphocyte development in young and aged mice." Click to view the E-thesis via HKUTO, 2003. http://sunzi.lib.hku.hk/hkuto/record/B31971076.

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12

Zhu, Lei 1980. "Perturbed B cell development in young B7.2 transgenic mice." Thesis, McGill University, 2005. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=84090.

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The best-characterized costimulation system for naive T cell activation is the interaction between CD28 and B7.1 or B7.2 ligands expressed on antigen-presenting cells such as activated B cells. Unexpectedly, transgenic mice with constitutive expression of B7.2 on B lymphocytes do not develop systemic autoimmune diseases, but rather exhibit a reduction of the B cell compartment that involves a defect in B cell maturation occurring very early in the ontogeny. In this study, we show that the early B cell loss is accompanied by splenomegaly and lymphoadenopathy that are due to a dramatic an

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13

黎若愚 and Yeuk-yu Lai. "Characterization of lymphocyte development in young and aged mice." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2003. http://hub.hku.hk/bib/B31971076.

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14

Carpenter-Holmes, Arthur Alexander. "Home Not Hospice, an integrated community for young and old in Old Town Alexandria, Virginia." Thesis, Virginia Tech, 2001. http://hdl.handle.net/10919/31197.

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The following thesis presents the design for a housing complex. The complex provides homes for two different segments of our population: single families and older or disabled persons and couples. Located in Old Town Alexandria Virginia, the project sits on the banks of the Potomac River. The question of integration is central to this thesis. The first design challenge is to integrate the older persons and persons with disabilities into the community. Successfully done, this will prevent the sense of separation and isolation that can often result when peopleâ s physical limitations restrict

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15

Davis, Craig. "Role of IL-12 in T cell activation in old mice." Connect to resource, 2008. http://hdl.handle.net/1811/32257.

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16

Speranza, Filippo. "Binocular detection of masked signals in young and old observers." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp04/nq41044.pdf.

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17

Perina, Sibilla <1970&gt. "Young and old star clusters in M31: an HST view." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2010. http://amsdottorato.unibo.it/2851/1/perina_sibilla_tesi.pdf.

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18

Perina, Sibilla <1970&gt. "Young and old star clusters in M31: an HST view." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2010. http://amsdottorato.unibo.it/2851/.

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19

Marsh, Frances J. "The behavioural ecology of young baboons." Thesis, University of St Andrews, 1993. http://hdl.handle.net/10023/15097.

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It is hypothesised that young baboons are potentially vulnerable to the effects of seasonal stress. Data were collected on the behaviour of this age group during a 12 month field study of a troop of olive baboons (Papio anubis) on the Laikipia plateau, Kenya, using a hand-held computer and a new program written by the author. Long-term environmental records for this site were continued. At this site there is a seasonal pattern of rainfall with inter-annual variation. Measures of biomass indicate that there are seasonal fluctuations in baboon food availability. Patterns in the occurrence of one

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20

Copple, Timothy DeVita Paul. "STRIDE LENGTH MANIPULATION IN YOUNG AND OLD ADULTS DURING LEVEL WALKING." [Greenville, N.C.] : East Carolina University, 2010. http://hdl.handle.net/10342/2706.

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21

Yocum, Amanda A. "Employing Strategy in Measures of Executive Functioning: Young Versus Old Adults." Cleveland, Ohio : Cleveland State University, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=csu1210296951.

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Thesis (M.A.)--Cleveland State University, 2008.<br>Abstract. Title from PDF t.p. (viewed on July 7, 2008). Includes bibliographical references (p. 31-36). Available online via the OhioLINK ETD Center. Also available in print.

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22

Pahuja, Surbhi. "Bandwidth feedback effects on retained movements in young and old adults." Thesis, California State University, Long Beach, 2014. http://pqdtopen.proquest.com/#viewpdf?dispub=1527573.

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<p> Feedback representing a performer's success for a given response has long been considered a critical factor in motor learning. Numerous studies of learning from augmented feedback have produced ambiguous guidelines for frequency design-some have recommended minimal feedback, whereas others have advocated more extensive feedback. Due to conflicting opinions regarding the frequency of Knowledge of Results, this study aimed to identify how young and old adults retain motor skills when two different frequency schedules of augmented feedback, everytrial and bandwidth are provided in acquisition

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23

Cavalier, Bethanie Anne. "Attachment Theory: Comparing the Relationship between Attachment Hierarchies and Life Satisfaction among Young-Old and Mid-Old Adults." University of Akron / OhioLINK, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=akron1573152367754282.

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24

Jenstad, Lorienne M. "The effect of temporal envelope changes on recognition of normal rate and time-compressed speech by young-old and old-old hearing-impaired listeners /." Thesis, Connect to this title online; UW restricted, 2005. http://hdl.handle.net/1773/8270.

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25

Shammi, Prathiba. "Humor in brain-damaged patients and neurologically intact young and old people." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp02/NQ41576.pdf.

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26

Choi, Ka-yi, and 蔡嘉儀. "The impacts of adventure-based counseling training on the young old helpers." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2009. http://hub.hku.hk/bib/B45167667.

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27

Abeln, Sanne. "Protein fold evolution on completed genomes : distinguishing between young and old folds." Thesis, University of Oxford, 2007. http://ora.ox.ac.uk/objects/uuid:b520fd65-e829-4ae0-bed6-47d642909889.

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We review fold usage on completed genomes in order to explore protein structure evolution and assess the evolutionary relevance of current structural classification systems (SCOP and CATH). We assign folds on a set of 150 completed genomes using fold recognition methods (PSI-BLAST, SUPERFAMILY and Gene3D). The patterns of presence or absence of folds on genomes gives us insights into the relationships between folds and how we have arrived at the set of folds we see today. In particular, we develop a technique to estimate the relative ages of a protein fold based on genomic occurrence patterns

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28

Snyder, Benjamin J. "Immunological Aspects of Muscle Injury and Regeneration in Young and Old Rats." Ohio University / OhioLINK, 2002. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1016641263.

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29

Gordon, Robert L. "A comparison of exhaled breath nitric oxide between old and young individuals." [Tampa, Fla.] : University of South Florida, 2004. http://purl.fcla.edu/fcla/etd/SFE0000346.

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30

Tuttle, Tiffany L. "Old designs for young people art, innovation and cultural continuity in Kyrgyzstan /." Online access for everyone, 2005. http://www.dissertations.wsu.edu/Thesis/Spring2005/t%5Ftuttle%5F050205.pdf.

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31

Cameron, John. "Endothelial junctions in the periodontal ligament microvasculature of young and aged mice /." Title page, contents and introduction only, 1995. http://web4.library.adelaide.edu.au/theses/09DM/09dmc182.pdf.

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32

Arefin, Sharmin. "Effect of tendon mechanical properties on force steadiness in young and old adults." Thesis, University of British Columbia, 2015. http://hdl.handle.net/2429/54270.

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The contribution of the tendon to age-related differences in elbow flexor force steadiness has not been studied. The purpose of this study was to investigate the effect of tendon compliance on force steadiness in young compared with old males during sustained submaximal isometric elbow flexion contractions. Force steadiness and tendon properties were measured in ten young (22.4 ± 3.7 years; 166.9 ± 11.8 cm; 74.3 ± 13.2 kg), and ten old (77.3 ± 5.3 years; 168.9 ± 14.1 cm; 84.6 ± 13.5 kg) healthy physically active males at 6 submaximal forces of 2.5%, 5%, 10%, 20%, 40%, and 60% maximal voluntary

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33

Eiben, Gabriele. "Overweight and obesity in the young and old : prevalence, prevention and eating behavior /." Göteborg : Dept. of Public Health and Community Medicine, Primary Health Care, The Sahlgrenska Academy, Göteborg University, 2007. http://hdl.handle.net/2077/3144.

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34

Holmes, Thomas R. "An attempt to compare fixed-interval responding between old and young Syrian hamsters." Virtual Press, 1986. http://liblink.bsu.edu/uhtbin/catkey/459121.

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This study investigated the effects of age on behavior controlled by temporal contingincies and also describes bar press responding by an animal infrequently used in the operant laboratory: the Syrian hamster. A review of the literature revealed a paucity of research on aging and temporal control thus providing an impetus for the study. The performance of four young (12months) and four old (24+months) male Syrian hamsters on Fixed-Interval schedules o f reinforcement was analyzed according t o post-reinforcement-pause duration, response rate, running rate, and cummulative record measures. Fa

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35

Patel, Priyank K. "Retention performance in young and old adults with high or low contextual interference." Thesis, California State University, Long Beach, 2014. http://pqdtopen.proquest.com/#viewpdf?dispub=1527020.

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<p> Research on motor learning between old and young adults has shown that young adults benefit from high levels contextual interference (CI) and perform faster than older adults. This project analyzed retention performance in young and older adults with high CI and low CI from a previously completed study for insights about similarities and differences in motor retention. Specifically, young (21-39 years) and old (>71 years) participants performed under random (high CI) and blocked (low CI) practice to determine which practice condition facilitated the retention of motor performance. Particip

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36

Thomas, Kathy Wright. "Voice Onset Time Characteristics of Selected Phonemes in Young and Old Male Speakers." Thesis, North Texas State University, 1985. https://digital.library.unt.edu/ark:/67531/metadc500707/.

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The purpose of the investigation was to compare mean voice onset time in young and old male subjects, as well as to examine variability of VOT productions with age for prevocalic bilabial, alveolar, and velar voiced and voiceless stop consonants. Forty-five Caucasion.males were divided equally into three.age groups. Ten tokens of six stimulus words were recorded and wide band spectrograms were made. Results of an analysis of variance revealed no significant differences in VOT with age when averages of the phonemes were used for analysis; however, a significant interaction between age and voice

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37

Adams, Charlotte Lynne 1971. "Tandem MS/MS analysis of band 3 protein from young and old erythrocytes." Diss., The University of Arizona, 1997. http://hdl.handle.net/10150/282574.

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Every day, billions of senescent human erythrocytes are removed from the circulation. The mechanism of recognition involves the formation of a neo-antigen on senescent cells, which binds autologous immunoglobulin and targets the senescent cell for phagocytosis. This neo-antigen is derived from an existing integral membrane protein, band 3. The molecular mechanisms underlying the formation of this neo-antigen during the aging process are poorly understood, but oxidative damage is suggested to be a critical event. Several post-translational modifications have been associated with aging that may

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38

Cheung, Amanda Fung-ping. "Schwann cells promote axonal regeneration of retinal ganglion cells in young postnatal mice." Thesis, University of Oxford, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.400561.

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39

Siemens, Penni Gay. "A Comparison of the Cohesion in the Expository Discourse of the Optimally-Healthy Young-Old and the Optimally-Healthy Oldest-Old." PDXScholar, 1994. https://pdxscholar.library.pdx.edu/open_access_etds/4781.

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The group of people aged 85 years and older is the fastest growing chronological population on the United States (Neal et al., 1993), and while a considerable amount of research has focused on the language of the elderly (those over 65 years), relatively little study has focused specifically on those aged 85 and older. This study is valuable in that it includes a large sample of optimally healthy people aged 85 and older. This sample of the optimally-healthy oldest-old will help define what changes, if any, are a function of age alone and what changes are clinical (associated with some disease

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40

Martineau, Louis C. "Myocardial glucose transport system related proteins, the effects of aging and exercise in old mice." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp04/mq24205.pdf.

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41

Goalen, Sarah. "An exploration of a mindfulness intervention with 7 and 8-year-old children." Thesis, University of Manchester, 2013. https://www.research.manchester.ac.uk/portal/en/theses/an-exploration-of-a-mindfulness-intervention-with-7-and-8yearold-children(257e6fbb-9db1-4421-92f3-fa9fa9658f54).html.

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Mindfulness has been defined as having three core aspects: active attention which leads to awareness, a regard for the present rather than the future or the past and an approach that is non-judgemental and accepting (Hooker and Fodor, 2008). Mindfulness has been used to treat adults and children in a clinical setting with presenting issues such as anxiety and difficulties related to poor self-regulation. The current research aimed to explore the effect of mindfulness on self-regulation and the feasibility of using mindfulness in a mainstream primary setting as a preventative, universal measure

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42

Ellis-Hale, Brandon K. "The effect of ß-blockade on VO¦2 kinetics in young and old males." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp01/MQ39821.pdf.

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43

Coon, Vicky Elizabeth. "An examination of information preservation in mental arithmetic performance for young and old adults." Thesis, Georgia Institute of Technology, 1993. http://hdl.handle.net/1853/28625.

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44

Lajoie, Brooke L. "Never too old, never too young? : exploring stereotypes in the mixed-age college classroom." Honors in the Major Thesis, University of Central Florida, 2010. http://digital.library.ucf.edu/cdm/ref/collection/ETH/id/1447.

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This item is only available in print in the UCF Libraries. If this is your Honors Thesis, you can help us make it available online for use by researchers around the world by following the instructions on the distribution consent form at http://library.ucf.edu/Systems/DigitalInitiatives/DigitalCollections/InternetDistributionConsentAgreementForm.pdf You may also contact the project coordinator, Kerri Bottorff, at kerri.bottorff@ucf.edu for more information.<br>Bachelors<br>Sciences<br>Psychology

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45

Lasher, Michael P., and Jill D. Stinson. "Old Enough to Know Better? Racial Biases, Perceived Age, and Young Defendants in Tennessee." Digital Commons @ East Tennessee State University, 2015. https://dc.etsu.edu/etsu-works/7962.

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A defendant’s age can be an important determinant of judicial outcomes, but the perception of a defendant’s age can have implications for how these outcomes are determined. Research has suggested a connection between racial bias and age perception. This study sought to describe an age bias against African-Americans, and to connect this to jury sentencing outcomes. Undergraduate participants (N = 318) were recruited from university in the Appalachia region. First, participants estimated the ages of individuals in photographs. Analyses primarily focused on 18 and 19-year-old African-American and

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46

Lasher, Michael P., and Jill D. Stinson. "Old Enough to Know Better? Racial Biases, Perceived Age, and Young Defendants In Tennessee." Digital Commons @ East Tennessee State University, 2014. https://dc.etsu.edu/etsu-works/7967.

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A defendant’s age can be an important determinant of judicial outcomes, but the perception of a defendant’s age can have implications for how these outcomes are determined. Research has suggested a connection between racial bias and age perception. This study sought to describe an age bias against African-Americans, and to connect this to jury sentencing outcomes. Undergraduate participants (N = 318) were recruited from university in the Appalachia region. First, participants estimated the ages of individuals in photographs. Analyses primarily focused on 18 and 19-year-old African-American and

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47

Blanco, Villarreal Martha P. "THE RELATIONSHIP BETWEEN JUSTICE PERCEPTIONS, CONSCIENTIOUSNESS AND WORKPLACE BEHAVIORS AMONG OLD AND YOUNG EMPLOYEES." CSUSB ScholarWorks, 2019. https://scholarworks.lib.csusb.edu/etd/836.

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This research addressed the influence employee age has on organizational justice perceptions (OJPs) and organizational citizenship behaviors (OCBs) through conscientiousness. Given the valuable contributions of older employees in the workforce, the aim of this study was to investigate the processes by which age affects justice perceptions, the expression of conscientiousness traits, and workplace behaviors. Additionally, a theoretical framework was provided where the conservation of resource, equity, fairness, socioemotional selectivity, and conscientiousness at work theorieshelp explain the l

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48

Sandberg, Petra. "Cognitive training in young and old adults : Transfer, long-term effects, and predictors of gain." Doctoral thesis, Umeå universitet, Institutionen för psykologi, 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-96719.

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Aging, also in the absence of pathological conditions, is associated with cognitivedecline, especially in so called fluid abilities, such as episodic memory andexecutive functions. Due to an ongoing demographic shift, a larger part of thepopulation will reach higher ages, and more people will be affected by age-relatedcognitive decline. Finding ways of counteracting this development have the potentialof having large benefits for both individuals and society. It has long beenknown that living in environments that are rich in terms of cognitive challengescan affect cognitive ability in old age.

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49

Oommen, Elizabeth R. "Effects of Three Lingual Conditions on Submental Muscle Activity in Healthy Young and Old Adults." Ohio University / OhioLINK, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1364210837.

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50

Raglin, Whitney J. "Growing old at a young age do depressive symptoms result in a shortened time perspective? /." Connect to resource, 2009. http://hdl.handle.net/1811/37241.

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