Academic literature on the topic 'Amodiaquine'

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Journal articles on the topic "Amodiaquine"

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&NA;. "Amodiaquine." Reactions Weekly &NA;, no. 536 (1995): 4. http://dx.doi.org/10.2165/00128415-199505360-00009.

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&NA;. "Amodiaquine." Reactions Weekly &NA;, no. 886 (2002): 6. http://dx.doi.org/10.2165/00128415-200208860-00013.

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&NA;. "Amodiaquine." Reactions Weekly &NA;, no. 1317 (2010): 12. http://dx.doi.org/10.2165/00128415-201013170-00031.

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Bloland, Peter B., and Trenton K. Ruebush. "Amodiaquine." Lancet 348, no. 9042 (1996): 1659–60. http://dx.doi.org/10.1016/s0140-6736(05)65723-6.

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Mariga, S. T., J. P. Gil, C. Sisowath, W. H. Wernsdorfer, and A. Björkman. "Synergism between Amodiaquine and Its Major Metabolite, Desethylamodiaquine, against Plasmodium falciparum In Vitro." Antimicrobial Agents and Chemotherapy 48, no. 11 (2004): 4089–96. http://dx.doi.org/10.1128/aac.48.11.4089-4096.2004.

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ABSTRACT The in vitro activity of the prodrug amodiaquine and its metabolite monodesethyl-amodiaquine has been studied for three strains of Plasmodium falciparum: LS-2, LS-3, and LS-1. Both compounds showed significant activity against all three strains; the activity of amodiaquine was slightly higher than that of the metabolite. By use of a checkerboard design, interaction studies with both compounds yielded evidence of significant synergism; means of the sums of the fractional inhibitory concentrations were 0.0392 to 0.0746 for strain LS-2, 0.1567 to 0.3102 for strain LS-3, and 0.025 to 0.33
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Sowunmi, Akintunde, Tunde Balogun, Grace O. Gbotosho, Christian T. Happi, Ahmed A. Adedeji, and Fatai A. Fehintola. "Activities of Amodiaquine, Artesunate, and Artesunate-Amodiaquine against Asexual- and Sexual-Stage Parasites in Falciparum Malaria in Children." Antimicrobial Agents and Chemotherapy 51, no. 5 (2007): 1694–99. http://dx.doi.org/10.1128/aac.00077-07.

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ABSTRACT The activities of amodiaquine, artesunate, and artesunate-amodiaquine against asexual- and sexual-stage parasites were evaluated in 360 Nigerian children with uncomplicated Plasmodium falciparum malaria randomized to the standard dose regimens of the three drugs/combination. Clinical recovery from illness occurred in all children. There were no significant differences in fever clearance times. Patients treated with artesunate or artesunate-amodiaquine had significantly shorter parasite clearance times (1.4 ± 0.5 days or 1.4 ± 0.6 days versus 3.2 ± 2.3 days, P = 0.0001) and lower gamet
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Tarning, Joel, Palang Chotsiri, Vincent Jullien, et al. "Population Pharmacokinetic and Pharmacodynamic Modeling of Amodiaquine and Desethylamodiaquine in Women with Plasmodium vivax Malaria during and after Pregnancy." Antimicrobial Agents and Chemotherapy 56, no. 11 (2012): 5764–73. http://dx.doi.org/10.1128/aac.01242-12.

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ABSTRACTAmodiaquine is effective for the treatment ofPlasmodium vivaxmalaria, but there is little information on the pharmacokinetic and pharmacodynamic properties of amodiaquine in pregnant women with malaria. This study evaluated the population pharmacokinetic and pharmacodynamic properties of amodiaquine and its biologically active metabolite, desethylamodiaquine, in pregnant women withP. vivaxinfection and again after delivery. Twenty-seven pregnant women infected withP. vivaxmalaria on the Thai-Myanmar border were treated with amodiaquine monotherapy (10 mg/kg/day) once daily for 3 days.
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Beshir, Khalid, Colin J. Sutherland, Ioannis Merinopoulos, et al. "Amodiaquine Resistance in Plasmodium falciparum Malaria in Afghanistan Is Associated with the pfcrt SVMNT Allele at Codons 72 to 76." Antimicrobial Agents and Chemotherapy 54, no. 9 (2010): 3714–16. http://dx.doi.org/10.1128/aac.00358-10.

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ABSTRACT Mutations in the Plasmodium falciparum genes pfcrt and pfmdr1 are selected by amodiaquine treatment in Africa. To examine the importance of these mutations in amodiaquine-treated Asian parasites, we determined pre- and posttreatment genotypes for amodiaquine treatment failures from a clinical trial in Afghanistan. The pfcrt codon 72 to 76 haplotype SVMNT was present in all samples tested, both before and after treatment. Amodiaquine did not clearly select for any pfmdr1 genotype, but a novel mutation, pfmdr1 N86F, was detected in four samples. We provide in vivo data to support the in
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Walimbwa, Stephen I., Mohammed Lamorde, Catriona Waitt, et al. "Drug Interactions between Dolutegravir and Artemether-Lumefantrine or Artesunate-Amodiaquine." Antimicrobial Agents and Chemotherapy 63, no. 2 (2018): e01310-18. http://dx.doi.org/10.1128/aac.01310-18.

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ABSTRACT Across sub-Saharan Africa, patients with HIV on antiretrovirals often get malaria and need cotreatment with artemisinin-containing therapies. We undertook two pharmacokinetic studies in healthy volunteers, using standard adult doses of artemether-lumefantrine or artesunate-amodiaquine given with 50 mg once daily dolutegravir (DTG) to investigate the drug-drug interaction between artemether-lumefantrine or artesunate-amodiaquine and dolutegravir. The dolutegravir/artemether-lumefantrine interaction was evaluated in a two-way crossover study and measured artemether, dihydroartemisinin,
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Gil, Jose Pedro. "Amodiaquine pharmacogenetics." Pharmacogenomics 9, no. 10 (2008): 1385–90. http://dx.doi.org/10.2217/14622416.9.10.1385.

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Dissertations / Theses on the topic "Amodiaquine"

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Clarke, Janet Barbara. "Immunogenicity and antigenicity of amodiaquine." Thesis, University of Liverpool, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.316558.

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Winstanley, Peter Andrew. "The pharmacology and toxicology of amodiaquine." Thesis, University of Liverpool, 1988. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.237571.

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Jewell, Hayley. "The role of metabolism in the toxicity of amodiaquine." Thesis, University of Liverpool, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.240477.

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Benaphtali, Pascale. "Rôle de la phase hépatique dans la toxicité de deux antimalariques : l'amodiaquine et la primaquine." Paris 5, 1993. http://www.theses.fr/1993PA05P105.

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Hough, Sally Jane. "Development of animal models to investigate drug-induced toxicity." Thesis, University of Liverpool, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.266265.

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Meyer, Gilles. "Hepatites aigues a l'amodiaquine : a propos d'un cas et revue de la litterature." Université Louis Pasteur (Strasbourg) (1971-2008), 1989. http://www.theses.fr/1989STR1M047.

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Paunescu, Emilia. "Design, synthèse, analyse structurale et activité antipaludique des nouveaux analogues de l'amodiaquine et l'amopyroquine." Lille 2, 2007. http://www.theses.fr/2007LIL2S013.

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Une première direction de recherche a été centrée sur la conception, synthèse, analyse structurale et activité antipaludique de nouveaux analogues de l'amodiaquine et de l'amopyroquine. Après une introduction sur le paludisme, les mécanismes d'action des médicaments de la famille des 4-aminoquinoléiques, la structure et les propriétés thérapeutiques de ces composés, notre étude s'est focalisée sur l'amodiaquine et ses principaux dérivés. Notre approche stratégique ainsi que les produits cibles du projet sont présentés, mettant en évidence des fonctions d'intérêt, susceptibles d'apporter la div
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Christie, Gary. "The role of disposition in drug immunogenicity." Thesis, University of Liverpool, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.384515.

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Orrell, Catherine. "Artesunate and amodiaquine : tolerability and drug interaction study in healthy normal volunteers." Master's thesis, University of Cape Town, 2005. http://hdl.handle.net/11427/3295.

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Antinarelli, Luciana Maria Ribeiro. "Atividade leishmanicida de derivados de quinolinas: 4-aminoquinolinas complexadas a esteroide e amodiaquina." Universidade Federal de Juiz de Fora (UFJF), 2013. https://repositorio.ufjf.br/jspui/handle/ufjf/5289.

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Books on the topic "Amodiaquine"

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Drugs for Neglected Diseases Initiative. The successful development of a fixed dose combination of artesunate plus amodiaquine antimalarial: Pioneering ways of working through innovative partnerships 2002-2015. DNDi, 2015.

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Book chapters on the topic "Amodiaquine"

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Mehlhorn, Heinz. "Amodiaquine." In Encyclopedia of Parasitology. Springer Berlin Heidelberg, 2015. http://dx.doi.org/10.1007/978-3-642-27769-6_140-2.

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Mehlhorn, Heinz. "Amodiaquine." In Encyclopedia of Parasitology. Springer Berlin Heidelberg, 2016. http://dx.doi.org/10.1007/978-3-662-43978-4_140.

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O’Neill, Paul M., Victoria E. Barton, Stephen A. Ward, and James Chadwick. "4-Aminoquinolines: Chloroquine, Amodiaquine and Next-Generation Analogues." In Treatment and Prevention of Malaria. Springer Basel, 2011. http://dx.doi.org/10.1007/978-3-0346-0480-2_2.

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"Amodiaquine." In Meyler's Side Effects of Drugs: The International Encyclopedia of Adverse Drug Reactions and Interactions. Elsevier, 2006. http://dx.doi.org/10.1016/b0-44-451005-2/00702-6.

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Scholar, Eric. "Amodiaquine." In xPharm: The Comprehensive Pharmacology Reference. Elsevier, 2007. http://dx.doi.org/10.1016/b978-008055232-3.61219-x.

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"Amodiaquine." In Meyler's Side Effects of Drugs. Elsevier, 2016. http://dx.doi.org/10.1016/b978-0-444-53717-1.00282-1.

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"AMODIAQUINE." In Litt's Drug Eruption and Reaction Manual. CRC Press, 2015. http://dx.doi.org/10.1201/b17996-13.

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Schulz, Thomas, Bridget Barber, and Damon Eisen. "Amodiaquine." In Kucers' The Use of Antibiotics Sixth Edition. CRC Press, 2010. http://dx.doi.org/10.1201/b13787-191.

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"Amodiaquine." In Dictionary of Toxicology. Springer Nature Singapore, 2024. http://dx.doi.org/10.1007/978-981-99-9283-6_142.

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"Amodiaquine." In Dictionary of Toxicology. Springer Nature Singapore, 2024. http://dx.doi.org/10.1007/978-981-99-9283-6_141.

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Conference papers on the topic "Amodiaquine"

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Adepiti, A., A. Adehin, O. Ogunlade, et al. "MAMA Decoction, an herbal antimalarial preparation, alters the disposition of amodiaquine in humans." In GA – 70th Annual Meeting 2022. Georg Thieme Verlag KG, 2022. http://dx.doi.org/10.1055/s-0042-1759287.

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Camara, Mahamadou Daby, Mamadou Tekete, Souleyman Dama, et al. "PA-594 CYP2C8*2 impacts desethylamodiaquine concentration upon repeated artesunate-amodiaquine treatment of uncomplicated malaria in Mali." In Abstracts of The Eleventh EDCTP Forum, 7–10 November 2023. BMJ Publishing Group Ltd, 2023. http://dx.doi.org/10.1136/bmjgh-2023-edc.245.

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