Relevant bibliographies by topics / Anti-Tubercular

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers

Academic literature on the topic 'Anti-Tubercular'

Author: Grafiati
Published: 2 June 2025
Last updated: 31 July 2025

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Journal articles on the topic "Anti-Tubercular"

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Sreelatha, Motimi, Bachu Naveena, and Yadala Prapurna Chandra. "A Review Study on Safety and Efficacy on Second Line Anti Tubercular Drugs." International Journal of Experimental and Biomedical Research 2, no. 3 (2023): 132–38. http://dx.doi.org/10.26452/ijebr.v2i3.538.

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Due to intestinal dysbiosis brought on by second-line anti-tubercular medication therapy, the patient's resistance to MTB appears to have decreased. This is likely due to an impact on immune cell proliferation and autophagic processes. therefore adversely influencing the patients' treatment results. The objectives of review articles are the safety and efficacy on the second line anti tubercular drugs. The results of these review article in the year 2015 to 2020. The conversation of these review article is the safety and efficacy of second line anti tubercular drugs . The discussion of these st
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Yogesh, Joshi 1. *. Rohit Bangwal 1. Shalini Rawat 1. Dev Singh Jangpani 2. "DRUG-INDUCED HEPATOTOXICITY OF ANTI-TUBERCULAR DRUGS THERAPY: A CASE REPORT." Journal of Pharma Research 8, no. 5 (2019): 266–68. https://doi.org/10.5281/zenodo.2678008.

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<strong><em>ABSTRACT</em></strong> <strong><em>A</em></strong><em>ccording to WHO, one third of the population is affected by TB and 1 in 4 adult male deaths is attributed to TB. The first line anti-TB drugs are potentially hepatotoxic. The incidence rate of anti-TB drugs induced hepatotoxicity has found to be 2% to 28% in India. A case of 62 years old man, weighing 49 kg was brought to hospital with chief complains of coughing, loss of appetite vomiting, melaena, fever, gastritis since 3 days. He had a history of pulmonary koch&rsquo;s 15 days back and was taking regular first line anti-tuber
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Chen, Wei, Pengmian Feng, and Fulei Nie. "iATP: A Sequence Based Method for Identifying Anti-tubercular Peptides." Medicinal Chemistry 16, no. 5 (2020): 620–25. http://dx.doi.org/10.2174/1573406415666191002152441.

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Background: Tuberculosis is one of the biggest threats to human health. Recent studies have demonstrated that anti-tubercular peptides are promising candidates for the discovery of new anti-tubercular drugs. Since experimental methods are still labor intensive, it is highly desirable to develop automatic computational methods to identify anti-tubercular peptides from the huge amount of natural and synthetic peptides. Hence, accurate and fast computational methods are highly needed. Methods and Results: In this study, a support vector machine based method was proposed to identify anti-tubercula
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Shrivastava, Rimjhim. "Anti-Tubercular Drugs Induced Hepatotoxicity." Annals of Pediatric Gastroenterology & Hepatology 3, no. 2 (2022): 1–3. http://dx.doi.org/10.5005/jp-journals-11009-0074.

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Kalani, Komal, Vinita Chaturvedi, Priyanka Trivedi, Sudeep Tondon, and Santosh Kumar Srivastava. "Dihydroartemisinin and its Analogs: A New Class of Antitubercular Agents." Current Topics in Medicinal Chemistry 19, no. 8 (2019): 594–99. http://dx.doi.org/10.2174/1568026619666190304142802.

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Background: Tuberculosis is one of the leading causes of mortality worldwide. Resistance against the frontline anti-tubercular drugs has worsened the already alarming situation, which requires intensive drug discovery to develop new, more effective, affordable and accessible anti-tubercular agents possessing novel modes of action. Objective: Chemical transformation of dihydroartemisinin for anti-tubercular lead optimization. Methods: Dihydroartemisinin, a metabolite of artemisinin was chemically converted into eight acyl derivatives and were evaluated for anti-tubercular potential against H37R
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Bangwal, Rohit, Yogesh Joshi, and Jagdish Kumar Rawat. "HEPATITIS INDUCED BY ANTI-TUBERCULAR THERAPY AND CHRONIC ALCOHOLISM: A CASE REPORT." Journal of Drug Delivery and Therapeutics 9, no. 4 (2019): 598–600. http://dx.doi.org/10.22270/jddt.v9i4.3205.

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Anti-tubercular drugs induced hepatotoxicity, which is a serious problem and it was reported that worldwide 2-32% of TB patients experience drug induced hepatotoxicity (DIH) during the course of the treatment. A 65 year old male, 47 kg weight and chronic alcoholic was brought to a tertiary care hospital in semi-conscious condition with chief complains of vomiting, cough with expectoration, loss of appetite, shortness of breath, fever (on &amp; off) since 4 days. He had a history of smear positive pulmonary koch’s 10 days back and was taking regular first line anti-tubercular drug therapy (Ison
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Mujeeb, Samar, Kuldeep Singh, Bhumika Yogi, Praveen Kumar, and Piyush Kumar. "Design, Synthesis and Anti-tubercular Evaluation of Some Novel Chroman-Hydrazone Derivatives." Asian Journal of Chemistry 35, no. 2 (2023): 483–92. http://dx.doi.org/10.14233/ajchem.2023.27002.

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The molecular docking, synthesis, spectral characterization and anti-tubercular evaluation of 10 novel N’-substituted-6-hydroxy-2,5,7,8-tetramethylchroman-2-carbohydrazide derivatives (SM1-SM10) were reported. The structures of the synthesized derivatives were affirmed by spectroscopic studies such as FTIR, 1H NMR, 13C NMR and high resolution-mass spectrometry. Predicted ADME and toxicity investigations were accomplished to presume the pharmacokinetic parameters of the compounds. The synthesized compounds were evaluated for in vitro anti-tubercular activity against Mycobacterium tuberculosis H
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J., Madhusudhanan. "Investigation of Anti-tubercular Activity of Solanum Nigrum." Journal of Advanced Research in Dynamical and Control Systems 12, SP4 (2020): 1473–87. http://dx.doi.org/10.5373/jardcs/v12sp4/20201626.

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Mohiuddin, Md, and J. Ashraful Haq. "First Line Anti-Tubercular Drug Resistance Pattern of Mycobacterium Tuberculosis Isolated From Specialized Hospitals of Dhaka City." Ibrahim Medical College Journal 8, no. 2 (2016): 41–46. http://dx.doi.org/10.3329/imcj.v8i2.26677.

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The present study was undertaken to determine the drug resistance pattern of M. tuberculosis isolated from 225 pulmonary and 45 extrapulmonary tuberculosis cases. The samples were cultured on Lowenstein Jensen (L-J) media for isolation of M. tuberculosis. Drug resistance to first line anti tubercular drugsnamely isoniazid (INH), rifampicin (RIF), Ethambutol (ETH) and streptomycin (SM) were determined by indirect proportion method. The overall drug resistance of M. tuberculosis was 53.6% to any of the first line anti tubercular drugs. Rate of multi drug resistant tuberculosis (MDR-TB) among the
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Bangwal, Rohit, Mashud Mohd Essar Hussain, Saurabh Saklani, Prashant Mathur, and Yogesh Joshi. "Hepatotoxicity Induced by Anti-Tubercular Drugs Therapy: A Case Report." Journal of Drug Delivery and Therapeutics 10, no. 5-s (2020): 195–98. http://dx.doi.org/10.22270/jddt.v10i5-s.4463.

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Anti-tubercular therapy induced liver injury (ATTILI) is the most important risk for the past many years. Many pre-existing factors and conditions like persisting liver injury, female gender, alcohol abuse etc. are important risk factors for the ATT induce liver injury. I read many case reports and literature review for the drugs induce liver injury, and concluded the results, ATT drugs are the most responsible for the liver injury during the therapy periods. The present case was 42-year-old male patient and known case of pulmonary tuberculosis, patients were on the ATT drugs therapy in the la
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Dissertations / Theses on the topic "Anti-Tubercular"

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Dauda, Khadijah Tolulope. "Metal complexes of anti-tubercular drugs." Thesis, University of Cape Town, 2018. http://hdl.handle.net/11427/28427.

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There is a continuing need to improve anti-tubercular drugs due to the development of resistance towards existing drugs. In some cases, metal complexes are known to improve the bioavailability of drugs. Hence the present study looks at the use of metal complexes of anti-tubercular drugs to improve the permeability and bioavailability of the drugs. The anti-tubercular drugs isoniazid (ISO), ethambutol (EMB), para-aminosalicylic acid (PAS), rifampicin (RFN) and pyrazinecarboxamide (PZA) were used in this study. Since the solubility and hence permeability and bioavailability of the drugs depend o
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Nkanga, Christian Isalomboto. "Inhalable particulate systems for anti-tubercular drug delivery." Thesis, Rhodes University, 2017. http://hdl.handle.net/10962/37966.

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Tuberculosis (TB) is a deadly infectious microbial disease that is currently dominating public health concerns. Among the pharmacological issues in the management of TB are the poor bioavailability of some anti-TB drugs, mostly due to the fast first-pass metabolism, and high drug load needed for combination therapy. These result in a lengthy treatment with several adverse effects causing decreased patient compliance. These factors often lead to the therapeutic failure and promote the development of drug resistant strains, justifying the urgent need for new therapeutic strategies. Liposomes are
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Shah, Manish Bipin. "The development of novel quinols as anti-tubercular agents." Thesis, University of Nottingham, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.431861.

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Cox, Jonathan A. G. "Identifying the mode of action of novel anti-tubercular drugs." Thesis, University of Birmingham, 2015. http://etheses.bham.ac.uk//id/eprint/6278/.

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The demand for novel antibiotics in the treatment of infections by \(Mycobacterium\) \(tuberculosis\) (\(M.\) \(tb\)), the causative agent of tuberculosis (TB) has reached new highs with the recent emergence of totally-drug resistant TB (TDR-TB). Efforts to develop antibiotics with revolutionary mechanisms of action, low minimal inhibitory concentrations (MICs) that will decrease the current drug burden and clear infection without compromising side effects has led to several collaborative efforts between pharmaceutical companies and academic institutions throughout the world. This interdiscipl
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Joseph, Laurelle Margaux. "Supramolecular derivatisation of new anti-tubercular and antimalarial drug leads." Master's thesis, University of Cape Town, 2015. http://hdl.handle.net/11427/19974.

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The UCT Drug Discovery and Design Centre, H3D, provided anti-tubercular and antimalarial drug leads that display potent in vitro and in vivo activity, but with unfavourable physicochemical properties. The primary objective of this study was to prepare supramolecular derivatives of the drug leads in an attempt to improve their physicochemical properties. Any new solid forms were to be characterized by a variety of analytical techniques, including X-ray analysis, spectroscopic and thermal techniques. Where possible, such derivatives would be tested for any enhancement in the aqueous solubility o
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Odumosu, Patricia. "Evaluation of the plant extracts of an anti-tubercular herbal remedy." Thesis, University of Sunderland, 2012. http://sure.sunderland.ac.uk/3330/.

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Ximenia americana root bark (Olacaceae) and Pavetta crassipes (Rubiaceae) leaf used in Nigerian traditional medicine were tested individually against clinical isolate of Mycobacterium tuberculosis by Lowenstein - Jensen method. Crude aqueous extracts of X. americana and P. crassipes exhibited minimum inhibitory activity (MIC) of 100 μg/mL and 200 μg/mL respectively. Sequential screening with solvents of different polarities was used in evaluation tests to readily locate the source of the activity against tuberculosis and for conditions related to skin diseases since it was readily available. I
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Bensaber, Salah M. "The design and synthesis of thiolactomycin analogues as potential anti-tubercular agents." Thesis, University of Strathclyde, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.501828.

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TB is the second leading cause of morbidity world wide caused by a single infectious organism. One third of the world's population are infected with the causative agent, Mycobacterium tuberculosis, and every year it kills 1.7 million people. There is an urgent need to find new Anti - TB that are efficacious, affordable and compatible with HIV and other Anti - TB used in developing countries, where the disease is prevalent. These drugs must also shorten treatment time and be active against resistant forms of the mycobacteria that will help increase patient compliance. One such lead compound whi
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Abuhammad, Areej. "Arylamine N-Acetyltransferases from mycobacteria : investigations of a potential target for anti-tubercular therapy." Thesis, University of Oxford, 2013. http://ora.ox.ac.uk/objects/uuid:3f571661-7b51-4fa8-bf5e-2adff9269c59.

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Reactivation of latent infection is the major cause of tuberculosis (TB). Cholesterol is a critical carbon source during latent infection. Catabolism of cholesterol contributes to the pool of propionyl-CoA, a precursor that is incorporated into cell-wall lipids. Arylamine N-acetyltransferase (NAT) is encoded within a gene cluster that is involved in the sterol-ring degradation and is essential for intracellular survival. NAT from M. tuberculosis (TBNAT) can utilise propionyl-CoA and therefore was proposed as a target for TB-drug development. Deleting the nat gene or inhibiting the NAT enzyme p
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Alsayed, Shahinda Sayed Rabie. "Design, Synthesis and Biological evaluation of Novel Indole2-carboxamide Derivatives as Anti-tubercular Agents." Thesis, Curtin University, 2021. http://hdl.handle.net/20.500.11937/88253.

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Singh, U. "Approach towards identification of anti-tubercular lead molecules by targeting mycobacterium tuberculosis glutamine synthetase." Thesis(Ph.D.), CSIR-National Chemical Laboratory, Pune, 2010. http://dspace.ncl.res.in:8080/xmlui/handle/20.500.12252/3748.

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Books on the topic "Anti-Tubercular"

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Marmorek's anti-tubercular serum in the treatment of pulmonary tuberculosis. s.n., 1997.

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Kayukova, L. A., A. V. Vologzhanina та E. M. Yergaliyeva. SPIROPYRAZOLINIUM COMPOUNDS AS A RESULT OF β-AMINOPROPIOAMIDOXIMES INTRAMOLECULAR REARRANGEMENTS. Daryn, Almaty, Kazakhstan, 2022. http://dx.doi.org/10.51580/2022-ebook.01.

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The monograph deals with unexpected rearrangements of β-aminopropioamidoxime derivatives, which form previously unknown spiropyrazolinium compounds. Recently we found that the 3,5-substituted 1,2,4-oxadiazoles, which are derivatives of β-aminopropioamidoximes, are of interest for practical medicine since they possess local anaesthetic, anti-tubercular and anti-diabetic properties. But when analyzing biological activity, it is necessary to take into account the chemical stability of the studied compounds. It turned out that 3,5-substituted 1,2,4-oxadiazoles taken for screening according to the
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Book chapters on the topic "Anti-Tubercular"

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Das, Shyamal C., and Peter J. Stewart. "Understanding the Respiratory Delivery of High Dose Anti-Tubercular Drugs." In Drug Delivery Systems for Tuberculosis Prevention and Treatment. John Wiley & Sons, Ltd, 2016. http://dx.doi.org/10.1002/9781118943182.ch13.

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Ameer and Chirom Aarti. "Liposomes as Robust Anti-Tubercular and Anticancer Drugs Delivery System." In Liposomes for Functional Foods and Nutraceuticals. Apple Academic Press, 2022. http://dx.doi.org/10.1201/9781003277361-7.

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Yadav, Mange Ram, Prashant R. Murumkar, Rahul B. Ghuge, Rahul R. Barot, and Monica Chauhan. "Exploring Decaprenylphosphoryl-β-d-Ribose 2′-Epimerase 1 (DprE1): A Target for Anti-tubercular Drugs." In Integrated Science. Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-15955-8_24.

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Kumar, Ankur, and Kuldeep K. Roy. "Computer-Aided Drug Design of Potential Anti-Tubercular Drug Targeting the Mycobacterial F-Type ATP Synthase Enzyme." In Global Trends in Health, Technology and Management. Springer Nature Switzerland, 2024. https://doi.org/10.1007/978-3-031-75457-9_11.

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Fatima, Samreen, Bhavya Bhardwaj, and Ved Prakash Dwivedi. "Targeting Host and Bacterial Signaling Pathways in Tuberculosis: An Effective Strategy for the Development of Novel Anti-tubercular Therapies." In Targeting Cellular Signalling Pathways in Lung Diseases. Springer Singapore, 2021. http://dx.doi.org/10.1007/978-981-33-6827-9_16.

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Saxena, Anil K. "Quantitative Structure Interaction Activity Relationship (QSIAR) as a Novel Approach to Drug Design: A Case Study of Anti-tubercular Agents." In Global Trends in Health, Technology and Management. Springer Nature Switzerland, 2024. https://doi.org/10.1007/978-3-031-75457-9_1.

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Mukhopadhyay, K. "Chapter-34 Anti Tubercular Drugs." In Viva Voce in Medical Pharmacology. Jaypee Brothers Medical Publishers (P) Ltd., 2004. http://dx.doi.org/10.5005/jp/books/11009_34.

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Thatikayala, Mahender, Anil Kumar Garige, and Hemalatha Gadegoni. "Benzimidazole: Pharmacological Profile." In Benzimidazole [Working Title]. IntechOpen, 2022. http://dx.doi.org/10.5772/intechopen.102091.

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Benzimidazole is a bicyclic heterocyclic aromatic compound in which benzene fused to imidazole moiety. Benzimidazole holds a vital role in the field of medicinal chemistry which possesses wide variety of pharmacological activities like antibacterial, anti cancer, antifungal, antileishmanial, anti tubercular, anti viral and anti malarial respectively, hence the benzimidazole moiety attracting the medicinal chemist to synthesize the different benzimidazole derivatives with wide variety of pharmacological activities. The book chapter mainly discussed the anti cancer, anti HIV, antileishmanial and
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"Anti-Tubercular Drug Designing Using Structural Descriptors." In Advances in Mathematical Chemistry and Applications, edited by Manish C. Bagchi and Payel Ghosh. BENTHAM SCIENCE PUBLISHERS, 2015. http://dx.doi.org/10.2174/9781681080529115020012.

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Mohan Sahoo, Biswa, Bera Venkata Varaha Ravi Kumar, Krishna Chandra Panda, et al. "Isoxazole Derivatives as Potential Pharmacophore for New Drug Development." In Frontiers in Medicinal Chemistry. BENTHAM SCIENCE PUBLISHERS, 2023. http://dx.doi.org/10.2174/9789815165043123100004.

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Isoxazoles are five-membered aromatic heterocyclic compounds in which oxygen and nitrogen atoms are present at positions 1 and 2 of the ring system. Isoxazole derivatives play a vital role due to their diverse biological activities, such as antimicrobial, antifungal, anti-viral, anti-tubercular, anti-epileptic, anti-diabetic, anticancer, anthelmintic, antioxidant, antipsychotic, antimalarial, analgesic, anti-inflammatory, etc. Isoxazole scaffold is present in various drug molecules, such as leflunomide (antirheumatic), valdecoxib (non-steroidal anti-inflammatory drug), and zonisamide (anti-con
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Conference papers on the topic "Anti-Tubercular"

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Bokhari, SA, G. Haque, A. Hamud, and JL Potter. "P221 Cutaneous adverse drug reactions to anti-tubercular drugs." In British Thoracic Society Winter Meeting 2024, QEII Centre, Broad Sanctuary, Westminster, London SW1P 3EE, 27 to 29 November 2024, Programme and Abstracts. BMJ Publishing Group Ltd and British Thoracic Society, 2024. http://dx.doi.org/10.1136/thorax-2024-btsabstracts.382.

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Marçalo, J., C. Garcia, L. Custódio, et al. "Anti-inflammatory and anti-tubercular properties screening of natural products from Plectranthus species." In GA 2017 – Book of Abstracts. Georg Thieme Verlag KG, 2017. http://dx.doi.org/10.1055/s-0037-1608136.

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Agrebi, Soumaya, Soumaya Ben Saad, Chaima Habouria, Hafaoua Daghfous, and Fatma Tritar. "Tolerance and side effects of second line anti tubercular drugs." In ERS International Congress 2017 abstracts. European Respiratory Society, 2017. http://dx.doi.org/10.1183/1393003.congress-2017.pa2705.

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Tiwari, Mani, Mahendra Patel, and Khyati Shamaliya. "Peripheral neuropathy in XDR-TB patients on second line anti-tubercular therapy." In Annual Congress 2015. European Respiratory Society, 2015. http://dx.doi.org/10.1183/13993003.congress-2015.pa2710.

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Sathyapriya, Sarah, Loh Chow Chin, and Wan Hazabbah Wan Hitam. "Presumed Ocular Tuberculosis – Challenges in Diagnosis." In 2nd International Conference on Public Health and Well-being. iConferences (Pvt) Ltd, 2022. http://dx.doi.org/10.32789/publichealth.2021.1010.

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Mycobacterium tuberculosis has a large spectrum of extra-pulmonary manifestations, and ocular tuberculosis is one of them. Diagnosis of ocular tuberculosis is often presumptive due to its extreme variability of ocular manifestations and difficulty isolating the organism through biopsy or culture. We report three cases of primary ocular tuberculosis with varied clinical presentations, namely neuroretintis, panuveitis, and occlusive vasculitis. Patients were aged 23 to 45 presented with symptoms of blurring of vision from 3 days to one week prior to presentation. Visual acuity ranged from 6/18 t
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Christopher, Devasahayam Jesudas, Deva Jedidiah, Barney Isaac, Binu Mathew, and Blessed Winston. "Anti-tubercular drug concentrations in Pulmonary Tuberculosis patients - Diabetic vs Non-Diabetic groups." In ERS International Congress 2019 abstracts. European Respiratory Society, 2019. http://dx.doi.org/10.1183/13993003.congress-2019.pa2999.

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Khurana, Alkesh, Vikas Gupta, Deepti Joshi, Abhishek Goyal, Kamendra Pawar, and Abhijit Pakhare. "Determinants of lymph node resolution in patients of tubercular lymphadenitis treated with anti tuberculous chemotherapy." In ERS International Congress 2018 abstracts. European Respiratory Society, 2018. http://dx.doi.org/10.1183/13993003.congress-2018.pa2686.

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Rakshit, Gourav, Sheikh Murtuja, and Venkatesan Jayaprakash. "Design, Development, and In Silico Study of Pyrazoline-Based Mycobactin Analogs as Anti-Tubercular Agents." In ECSOC-25. MDPI, 2021. http://dx.doi.org/10.3390/ecsoc-25-11767.

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Dar, Mohd Yousoof, Balakrishnan Menon, Harsh Vardhan, Sarfaraz Jamal, and Mohammad Noufal. "Study of inflammatory markers in sputum positive patients of pulmonary tuberculosis and its response to anti-tubercular treatment." In ERS International Congress 2016 abstracts. European Respiratory Society, 2016. http://dx.doi.org/10.1183/13993003.congress-2016.pa2702.

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Gupta, Gaurav S. N., and A. S. Chitnis. "Assessment of lung functions in patients of pulmonary tuberculosis(PTB) after completion of their anti-tubercular medicationGaurav Gupta, A.S Chitnis." In ERS International Congress 2018 abstracts. European Respiratory Society, 2018. http://dx.doi.org/10.1183/13993003.congress-2018.pa2750.

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