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Dissertations / Theses on the topic 'Antimicrobial Resistance AMR Antibiotics'

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Published: 5 June 2025

Last updated: 1 August 2025

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1

Malott, Bradley. "Development and investigation of antibiotic resistance in E. coli using aminoglycosides." Wittenberg University Honors Theses / OhioLINK, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=wuhonors1617617698561944.

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2

Murray, Aimee Kaye. "Selection for antibiotic resistance in the aquatic environment : novel assays to detect effect concentrations of micropollutants." Thesis, University of Exeter, 2017. http://hdl.handle.net/10871/30325.

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The environment is increasingly recognised as a key player in the emergence and mobilisation of antibiotic resistance, which negatively impacts human health, healthcare systems, and farming practices worldwide. Recent work has demonstrated concentrations of antibiotics in the natural environment may select for resistance in situ, but a scarcity of meaningful data has prevented rigorous environmental risk assessment of antibiotics. Without such data, mitigation strategies, such as improved antibiotic stewardship or environmental discharge limits, cannot be effectively designed or implemented. T

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3

Garlapati, Shailesh, and Vinana Sewoyo. "Improving Antibiotic Availability by Restructuring the Supply Chain : A Case Study Within Sweden." Thesis, Uppsala universitet, Industriell teknik, 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-395877.

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Rising Antimicrobial Resistance is a threat faced all over the world. Bacterial infections that were treatable with antibiotics only a few years ago can now lead to life-threatening conditions. This thesis is part of the work of a large platform, PLATINEA, trying to reduce the rate of new resistances occurring in Sweden by preventing non optimal treatment. Due to shortages of the right antibiotics, suboptimal antibiotics are prescribed, which has shown to be accelerating the resistances among the bacterial populations. This study proposes an information exchange database and a central storage

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4

Alghamdi, Saleh. "The adoption of antimicrobial stewardship programmes in Ministry of Health hospitals in Saudi Arabia." Thesis, University of Hertfordshire, 2018. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.768496.

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Aim: This thesis aims to explore and investigate the level and process of adoption of Antimicrobial Stewardship Programmes (ASPs) and factors influencing their implementation in Saudi Ministry of Health (MOH) hospitals. The findings of this study will provide hospitals and policy makers with evidence-based recommendations on how barriers to ASPs adoption can be overcome, which will ultimately improve antimicrobial use and reduce antimicrobial resistance (AMR). Method: A mixed method approach was carried out using both qualitative and quantitative research methods. Semi-structured interviews we

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5

CINTI, ALESSANDRO. "Needs for innovation in network: Problematizing the role of policy, producer, and user addressing AMR issue." Doctoral thesis, Università Politecnica delle Marche, 2022. https://hdl.handle.net/11566/303339.

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Gli antibiotici sono stati e sono tuttora medicinali essenziali per il trattamento delle malattie umane. Sono fondamentali per curare le infezioni tradizionali e le malattie rare. Tuttavia, fin dalla loro scoperta era già noto il problema dell’antibiotico resistenza. L’Antimicrobial Resistance (AMR) è quel fenomeno che avviene quando un battere riesce a sopravvivere in presenza di un antimicrobico, come ad esempio un antibiotico. Il problema è di rilevanza mondiale sia dal lato sanitario, attualmente, infatti l’AMR produce attualmente 1 milione di morti annui, sia dal lato economico, 50 trilio

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Jacob, Rebecca. "Lipid bilayers and their interactions with the antimicrobial peptide LL37: a TIR Raman study." Thesis, KTH, Skolan för kemivetenskap (CHE), 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-207018.

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As a direct consequence of the misuse of antibiotics since its first discovery, bacteria have developed extensive resistance mechanisms making them once again potential lethal threats. This eventuality has triggered a vast research effort from scientists worldwide to find solutions to mitigate antimicrobial resistance. One such option is the identification of new potential antimicrobial agents, like for example antimicrobial peptides (AMPs). Various methods have been applied to evaluate the properties and determine the complex mechanism of AMPs. However, the details of the mechanism remain unk

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7

Haykova, O. O. "Antimicrobial resistance. Causes and solving." Thesis, Sumy State University, 2018. http://essuir.sumdu.edu.ua/handle/123456789/66783.

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One of the triumphs of modern medicine is the development of antibiotics and other antimicrobial agents. The basis of the action of antibacterial drugs is to suspend the activity of pathogens due to inhibition of metabolic-specific microorganisms. But today the development of resistance to them by microbes begins to become challenge for scientists.

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8

Morgan, Marcella Alexandra. "Antimicrobial resistance in Staphylococcus aureas." Scholarly Commons, 1988. https://scholarlycommons.pacific.edu/uop_etds/2147.

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Susceptibility of 112 strains of Staphylococcus aureus obtained from Dameron Hospital, Stockton, California was tested with 18 antimicrobials . The MIC method was used with the following antimicrobials : tetracycline, oxacillin, penicillin, ampicillin, vancomycin, cefazolin, erythromycin, clindamycin, gentamycin, rifampin, trimethoprimsulfamethoxazole, chloramphenicol, and cefotaxime . The standard Kirby-Bauer disc diffusion method was used to test neomycin, tobramycin, and amikacin . Methicillin, oxacillin, and nafcillin were tested with a modified Kirby-Bauer method, which included the addit

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9

Frampton, Helen Kathleen. "Studies of resistance to Beta-lactam antibiotics in Bacillus licheniformis." Thesis, University of Cambridge, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.328977.

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10

Meiring, Jillian A. "Antimicrobial resistance patterns in a Port Elizabeth hospital." Thesis, Rhodes University, 1993. http://hdl.handle.net/10962/d1004104.

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Antibiotic resistance in clinical bacterial isolates remains an ongoing problem requiring continuous monitoring to effect some form of control. Comparative studies have not been previously reported for the Eastern Cape Region, South Africa and this study was undertaken to monitor resistance patterns in clinical isolates from Provincial Hospital, Port Elizabeth. Over the three year period 1989 to 1991, 9888 susceptibility results from isolates examined in the SAIMR pathology laboratory were analysed and collated using a stand-alone computer program. Resistance patterns for a range of nineteen a

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11

Dosselli, Ryan. "Photodynamic therapy and cationic antimicrobial peptides: strategies to overcome bacterial resistance to antibiotics." Doctoral thesis, Università degli studi di Padova, 2010. http://hdl.handle.net/11577/3426996.

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The worldwide rise of antibiotic resistance stimulates the search of new strategies for killing bacteria, whose mechanisms of action are different from those of antibiotics. Two promising strategies in this respect are the use of cationic antimicrobial peptides (CAMPs) and photodynamic therapy (PDT). Both approaches have been considered and some aspects elucidated during my PhD. Therefore, studies along two different research lines, having the same final aim and merging in the last part of the project, have been carried out. The first research line focused on PDT, in particular I investigated

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Mohamed, Hameem Fatima Sakeena. "Antimicrobial resistance and pharmacy students in Sri Lanka and Australia." Thesis, The University of Sydney, 2018. http://hdl.handle.net/2123/20693.

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This thesis opens with background information about the research presented in this thesis focussing on antimicrobial resistance (AMR) as a global challenge, contributing factors for the development and spread of AMR, the World Health Organization (WHO) Global Action Plan on AMR, the pharmacists’ role in guiding the appropriate use of antibiotics and the importance of education in addressing AMR. Furthermore, this introduction chapter describes the aims of the research presented in this thesis and provides an overview of this thesis (Chapter 1). The next chapter presents a systematic review of

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Vieira, Mónica Andreia Almeida. "Monitoring antibiotics in the environment. Study of Quinoxaline derivatives bioactivity." Doctoral thesis, Faculdade de Ciências e Tecnologia, 2013. http://hdl.handle.net/10362/11350.

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Dissertação para obtenção do Grau de Doutor em Química Sustentável<br>Antimicrobial agents have revolutionized medicine and promoted an increase in average life expectancy of human populations worldwide. These drugs are used not only in human medicine but also in veterinary practice, in the treatment and prevention of infections, and in some regions in the world, as well as growth promoters, ensuring a greater and better animal production. The use of antimicrobial agents in animal production causes contamination of the final product with drug residues that are eventually distributed in human

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14

Gravander, Nikkinen Anna, and Ellen Haglund. "Sjuksköterskans potentiella roll i antimicrobial stewardship : En litteraturöversikt." Thesis, Högskolan Väst, Avdelningen för omvårdnad - grundnivå, 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:hv:diva-16790.

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Background The antimicrobial stewardship is developed to provide a guide on the responsible use of antimicrobial drugs. Thus, slowing down the development of antimicrobial resistance. However, the nurse's role in antimicrobial stewardship is not clarified. Failure toinclude the nurse within the antimicrobial stewardship guidelines may result in poor execution of antimicrobial stewardship.Aim To explore the role of nurses in antimicrobial stewardship and how it can be practically implemented within the medical field.Method This is a literature review where seven qualitative studies, two quantit

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Vila, Farrés Xavier. "Development of new antimicrobial peptides and peptidomimetics and mechanism of resistance to peptide antibiotics." Doctoral thesis, Universitat de Barcelona, 2014. http://hdl.handle.net/10803/285375.

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Nowadays in the world there is a very big problem associated with two factors related to each other. The first factor is the increase in the resistant of certain bacteria, especially the bacteria from the ESKPAE group. The second factor is the dramatically decrease of new antibiotics approved by the FDA. These two problems show that there is an urgent need to find new antibiotics active against these resistant bacteria. In this thesis, we have tackled two different topics closely related in the race to find new antimicrobials. The first topic tackled was the knowledge of the mechanism of re

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16

Mainda, Geoffrey. "Molecular epidemiology of antimicrobial resistance (AMR) and Shiga toxin producing E. coli (STEC) in dairy herds of central Zambia." Thesis, University of Edinburgh, 2016. http://hdl.handle.net/1842/25416.

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Antimicrobial resistance (AMR) is a worldwide public health concern. While it is evident that the use of antibiotics creates selection pressure for the evolution of antibiotic resistance genes, there are still considerable knowledge gaps relating to the status quo of antibiotic use, emergence of resistant pathogens in different livestock production systems and spread within human and animal communities. This thesis includes a survey of antibiotic use in the dairy sector within a specific area of Zambia and analysis of AMR and virulence factors in E. coli isolated from dairy cattle and diarrhoe

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17

Mohrs, Simone. "Factors influencing the use of antibiotics and knowledge about antibiotic resistance in Jakarta : A qualitative study on the perceptions of stakeholders involved in Yayasan Orangtua Peduli’s Smart Use of Antibiotics campaign in Indonesia." Thesis, Uppsala universitet, Internationell mödra- och barnhälsovård (IMCH), 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-303379.

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Introduction: Southeast Asia has among the highest rates of antibiotic resistance worldwide, particularly in Indonesia, where paediatricians prescribed antibiotics to 94% of children, knowing that the infection was viral. Relevance: There is a gap in understanding of the reasons behind the irrational use of antibiotics by healthcare professionals and patients. Aim: This research aims to explore factors that influence the use of antibiotics and knowledge about antibiotic resistance in Jakarta, Indonesia. Methods: In December 2014, the researcher conducted thirteen semi-structured interviews wit

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Steuart, Rebecca. "Antibiotic Prescribing and Subsequent Antibiotic Resistance of Respiratory Cultures in Children with Tracheostomies." University of Cincinnati / OhioLINK, 2021. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1623170006733706.

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Olutuase, Victory Onize. "Assessment of antibiotic dispensing practices of community pharmacists in Jos, Plateau State, Nigeria." University of the Western Cape, 2019. http://hdl.handle.net/11394/6981.

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Master of Public Health - MPH<br>Background: The irrational use of medicines is a global public health challenge, particularly in developing countries like Nigeria. One of the consequences of irrational medicine use is rising antimicrobial resistance, which continues to contribute to the increase in morbidity, mortality, and high cost of care, despite breakthroughs in medicine and new treatment options. Community pharmacists have been identified as contributors to antimicrobial resistance through their antibiotic dispensing practices. However, there is little research on community pharmacists

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20

Hasan, Badrul. "Antimicrobial Resistance and Production of Extended Spectrum Beta-Lactamases in Enterobacteriaceae from Birds in Bangladesh." Doctoral thesis, Uppsala universitet, Klinisk mikrobiologi och infektionsmedicin, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-199686.

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The dissemination of members of the Enterobacteriaceae family with extended spectrum beta-lactamases (ESBLs) and metallo-beta-lactamases (MBLs) has become a global concern. ESBLs and MBLs have been reported in humans, domestic animals, wildlife and the environment, and their isolation frequencies are increasing rapidly worldwide. Most studies have been performed in developed countries and quite few in developing countries, where the antibiotic consumption is often poorly controlled. To explore the environmental contamination of antibiotic resistance in Bangladesh, and of ESBLs and MBLs in par

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Mohlakoana, Keneuoe. "Antimicrobial activity of selected Eastern Cape medical plants." Thesis, Nelson Mandela Metropolitan University, 2010. http://hdl.handle.net/10948/1199.

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Bacterial resistance to antibiotics has been a great problem for many years. The degree of resistance and the speed with which resistance develops varies with different organisms and different drugs. Enzymes called β-lactamases are produced by bacteria and are one mechanism in which bacteria develop antimicrobial resistance. Gram-negative bacteria producing enzymes called ESBLs because of their wide substrate range are of a particular concern in nosocomial infections. In many countries people still use traditional medicine derived from plants as an alternative to the Western medicine due to in

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Paulson, Philip Theodor. "California Livestock Owners: An Assessment of Familiarity with New Antimicrobial Rules and Access to Educational Outreach." DigitalCommons@CalPoly, 2019. https://digitalcommons.calpoly.edu/theses/2012.

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The purpose of this research is to support the California Department of Food & Agriculture (CDFA) with education and outreach about recent changes regarding antimicrobial use in livestock, and to enhance their emergency communications network. This was done by characterizing a population of small-scale livestock owners underserved with regards to educational outreach about animal health issues, such as antimicrobial use rules. The project also seeks to enhance public understanding of the importance of responsible antimicrobial use in animal and human health. To accomplish this, the study used

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23

Harris, Ryan A. "Identification Of Genes Involved In The Production Of Novel Antimicrobial Products Capable Of Inhibiting Multi-Drug Resistant Pathogens." Bowling Green State University / OhioLINK, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=bgsu1562068774992706.

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Chee, Xavier. "Rational development of new inhibitors of lipoteichoic acid synthase." Thesis, University of Cambridge, 2017. https://www.repository.cam.ac.uk/handle/1810/269766.

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Staphyloccocus aureus is an opportunisitic pathogen that causes soft skin and tissue infections (SSTI) such as endocarditis, osteomyelitis and meningitis. In recent years, the re-emergence of antibiotic-resistant S. aureus such as MRSA presents a formidable challenge for infection management worldwide. Amidst this global epidemic of antimicrobial resistance, several research efforts have turned their focus towards exploiting the cell-wall biosynthesis pathway for novel anti-bacterial targets. Recently, the lipoteichoic acid (LTA) biosynthesis pathway has emerged as a potential anti-bacterial t

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Verderosa, Anthony Daniel. "Nitroxide functionalised antibiotics for the eradication of bacterial biofilms." Thesis, Queensland University of Technology, 2019. https://eprints.qut.edu.au/135167/1/Anthony_Verderosa_Thesis.pdf.

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Bacterial biofilms are a leading cause of life-threatening and device-related infections worldwide. Biofilm related infections are notoriously difficult to treat as they are highly tolerant to conventional antibiotics. This project has designed and synthesised a new class of antibiotics to circumvent biofilm tolerance and shown that the prepared compounds could eradicate several medically important pathogens (P. aeruginosa, E. coli, and S. aureus). Importantly, as these compounds are hybrids of drugs that are already used clinically as stand-alone therapies, they demonstrate great potential to

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Odendaal, Clerisa. "Structure-function studies of peptide fragments derived from a defensin of the tick Ornithodoros savignyi Audouin (1827)." Diss., University of Pretoria, 2013. http://hdl.handle.net/2263/41020.

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Overuse of conventional antibiotics has led to increased multidrug resistant micro-organisms. Therefore, development of alternative drugs with new mechanisms of action in the control of resistant micro-organisms is urgently needed. Defensins, one of the larger groups of naturally occurring antimicrobial peptides (AMPs), found in a variety of species, may serve as templates for the development of novel therapeutic agents. The work completed in this study is based on an antimicrobial peptide (AMP), Os, derived from the C-terminus of a tick Ornithodoros savignyi defensin isoform 2 (OsDef2). OsDef

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Holz, Magdalena S. "Antibiotics and Antimicrobial Resistance: An Evaluation of the Knowledge, Attitude and Perception Among Dental Students and Academic Deans and Department Chairs within U.S. Dental Schools." VCU Scholars Compass, 2019. https://scholarscompass.vcu.edu/etd/5764.

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Purpose: This study aimed to survey current 3rd and 4th year dental students, academic deans, and department chairs within U.S. dental schools to analyze the level of understanding; education; guidelines; and overall awareness regarding antibiotic use within dentistry and antimicrobial resistance. Methods: A 25-question survey intended for 3rd and 4th year dental students and a 20-question survey intended for academic deans and various department chairs of U.S dental schools were each developed utilizing REDCap. The survey invitations were sent via e-mail to the current academic dean of each U

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Amachawadi, Raghavendra G. "Selection and co-selection of antimicrobial resistance in gut enterococci of swine and cattle fed diets supplemented with copper, tylosin, and chlortetracycline." Diss., Kansas State University, 2014. http://hdl.handle.net/2097/19765.

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Doctor of Philosophy<br>Department of Diagnostic Medicine/Pathobiology<br>H. Morgan Scott<br>Copper, as copper sulfate, is often used as an alternative to in-feed antibiotics for growth promotion in both swine and cattle diets. Gut bacteria exposed to copper can acquire resistance, which among enterococci is conferred by a plasmid-borne transferable copper resistance gene (tcrB). The plasmid also carries tetracycline [tet(M)] and macrolide [erm(B)] resistance genes. Because of the genetic link between acquired copper (tcrB) and antibiotic resistance in Enterococcus spp., we hypothesized that c

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Linde, Charlotte M. A. "Defense peptides against Mycobacteria /." Stockholm, 2005. http://diss.kib.ki.se/2005/91-7140-480-5/.

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Jorba, Pedrosa Marta. "Outer membrane: a key obstacle for new antimicrobial agents." Doctoral thesis, Universitat de Barcelona, 2021. http://hdl.handle.net/10803/672746.

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INTRODUCTION: Antimicrobial resistance is one of the world’s major challenges in both microbiology and public health since infections caused by multidrug-resistant bacteria are reaching alarming levels. The world is currently facing a global antibiotics crisis and some new strategies need to be explored to tackle these resistant infections. The outer membrane is a differential structure of Gram-negative bacteria that works as a highly effective selective permeability barrier. Thus, the permeation through the Gram- negative cell envelope is a challenge for drug compounds to reach their targe

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Bokhary, Hamid. "Policy Making by Tackling Antimicrobial Resistance in Mass Gatherings: Clinical Assessment and Tools for Prescribing Antibiotics for Upper Respiratory Tract Infections Among Hajj Pilgrims." Thesis, The University of Sydney, 2021. https://hdl.handle.net/2123/27099.

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Hajj is an annual religious mass gathering and Islamic pilgrimage that is a potential focal point for the global importation and exportation of infectious and antimicrobial resistant (AMR) organisms. Although, upper respiratory tract infections (URTIs) are common in Hajj, however, there is a lack of knowledge regarding the causative agents and any associated AMR profiles. Moreover, there is compelling evidence of inappropriate antibiotic prescription by Hajj deployed health care workers (HCWs) during the event. This thesis aims to address some of the factors that may arise when treating URTIs

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Ibrahim, Mohamad. "Evaluation of antibiotic use in a Lebanese hospital." Thesis, Cranfield University, 2016. http://dspace.lib.cranfield.ac.uk/handle/1826/10012.

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Antimicrobial resistance is a significant global health problem. Misuse of antibiotics is associated with antimicrobial resistance which presents clinicians with treatment challenges and increases the complexity of the decision making process related to the selection of appropriate antibiotic therapy. Antibiotic resistant organisms can often lead to nosocomial infections (NIs) and undoubtedly causes patient harm and increases healthcare costs. According to the National Institute of Allergy and Infectious Diseases (NIAID), at least 70% of the nosocomial infections are caused by antibiotic-resis

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Katvars, Laura K. "Novel cationic peptides and polymers in the treatment of methicillin-resistant Staphylococcus aureus and multi-drug resistant Acinetobacter spp. skin infection isolates." Thesis, University of Aberdeen, 2015. http://digitool.abdn.ac.uk:80/webclient/DeliveryManager?pid=228984.

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Broussou, Diane. "Développement d'un modèle in vitro dynamique innovant pour l'optimisation des schémas thérapeutiques des antibiotiques." Thesis, Toulouse 3, 2018. http://www.theses.fr/2018TOU30217/document.

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Parmi les stratégies d'amélioration des traitements des infections bactériennes chroniques, visant à accroître l'activité bactéricide ou à limiter la sélection de résistances, le développement de combinaisons d'antibiotiques existants constitue une stratégie prometteuse. L'objectif de cette thèse était d'évaluer l'efficacité d'une combinaison d'antibiotiques sur un biofilm bactérien dans un système in vitro dynamique qui permet de simuler les concentrations d'antibiotiques observées chez les patients traités. Nous avons montré que pour des infections complexes dues à de fortes charges bactérie

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Zai, Muhammad Jawad. "The interactive antimicrobial activities of conventional antibiotics with Terminalia sericea Burch. ex DC., Terminalia prunioides Laws. and Terminalia gazensis Bak. f. extracts against gastrointestinal pathogens." Thesis, Griffith University, 2022. http://hdl.handle.net/10072/412434.

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Antibiotic resistance is one of the biggest challenges facing medical researchers. Due to the decline in the discovery of new antimicrobial agents and an increase in antibiotic resistance, medical researchers have focused on alternative therapeutic treatments. Combinational therapies that involve medicinal plants and conventional antibiotics can address the issue of increasing resistance and may help reactivate drugs that are otherwise ineffective. Terminalia sericea, Terminalia prunioides and Terminalia gazensis are native South African medicinal plants with known antimicrobial properties. Ho

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Torell, Erik. "Epidemiology of Enterococci with Acquired Resistance to Antibiotics in Sweden : Special emphasis on Ampicillin and Vancomycin." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis : Univ.-bibl. [distributör], 2003. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-3344.

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Abukar, Ayan. "Synthetic biology and open science : the next frontier of antibiotic discovery and antimicrobial resistance research." Electronic Thesis or Diss., Université Paris Cité, 2023. http://www.theses.fr/2023UNIP7127.

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L'humanité a beaucoup progressé depuis l'époque où les infections courantes étaient considérées comme une condamnation à mort. Cependant, comme les organismes responsables de ces infections deviennent résistants aux traitements, nous sommes obligés de nous confronter à la réalité potentielle de l'ère post-antibiotique qui approche rapidement. La résistance aux antibiotiques évolue à un rythme qui dépasse considérablement les thérapies médicales existantes et il est urgent d'innover. L'objectif de mon doctorat est justement d'y parvenir en créant une plateforme de biologie synthétique à science

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Costa, Estela, and University of Lethbridge Faculty of Arts and Science. "Modulation of the immune system in the mammalian intestine as an alternate explanation for the action of antimicrobial growth promoters / Estela Costa." Thesis, Lethbridge, Alta. : University of Lethbridge, Dept. of Biological Sciences, c2010, 2010. http://hdl.handle.net/10133/2627.

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The novel hypothesis that antimicrobial growth promoters (AGP) function by modulating the mammalian immune system was tested. Sampling methods to characterize the mucosa-associated microbiota of the murine intestine by terminal restriction fragment length polymorphism (T-RFLP) analysis indicated that direct plug extraction was superior to wash methods. Using T-RFLP analysis, non-therapeutic administration of chlortetracycline (CTC) and sulfamethazine to beef cattle did not affect the composition of bacterial communities associated with intestinal mucosa and in digesta, with exception of those

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Anjuli, Borgonha. "Communicating Antibiotic Resistance to the Public: How effective was Public Health England’s 2018 ‘Keep Antibiotics Working’ campaign TV advertisement at increasing public understanding of antibiotic resistance and motivating a change in antibiotic seeking behaviours?" Thesis, Malmö universitet, Fakulteten för kultur och samhälle (KS), 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:mau:diva-21079.

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Antibiotic resistance is one of the greatest global threats we face today. Human overuse ofantibiotics is a contributing factor and major behaviour change around antibioticconsumption is needed, but several challenges exist in communicating antibiotic resistanceto the public. In 2018 the UK Government relaunched a national television advertisement aspart of the ‘Keep Antibiotics Working’ campaign which aimed to raise awareness of antibioticresistance and reduce public demand for antibiotics. This study evaluates what role theframing of antibiotic resistance in the advertisement played in incre

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López, Causapé Carla. "Clonal epidemiology and antimicrobial resistance in Pseudomonas aeruginosa chronic respiratory infections: interpatient transmission and resistome evolution of an international cystic fibrosis clone." Doctoral thesis, Universitat de les Illes Balears, 2018. http://hdl.handle.net/10803/666251.

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[eng] Chronic respiratory infection (CRI) by Pseudomonas aeruginosa is the main cause of morbidity and mortality in cystic fibrosis (CF). During the progression from early infection to chronic non-eradicable colonization P. aeruginosa undergoes a complex evolutionary adaptation and diversification process which eventually leads to a mixed and persistent infecting population in which multidrug resistant variants frequently rise compromising the selection of appropriate antibiotic therapies. In this work the interplay between three key microbiological aspects of these infections was investigat

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Lake, Alexandra E. "Identification of broad host range phage that antagonize multidrug resistant Pseudomonas aeruginosa and their therapeutic potential to restore antibiotic susceptibility among these pathogens." Bowling Green State University / OhioLINK, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=bgsu1594303799535431.

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PERGOLA, SILVIA. "Investigation of Campylobacter spp in broiler chickens from farm to retail." Doctoral thesis, Università Politecnica delle Marche, 2017. http://hdl.handle.net/11566/245382.

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Campylobacter spp è l’agente patogeno di origine alimentare più comune nell'Unione Europea (UE), con 236.851 casi umani confermati di campilobatteriosi nel 2014 (EFSA e l'ECDC, 2015). Le più comuni specie associate a campilobatteriosi sono Campylobacter jejuni, seguito da Campylobacter coli (EFSA e l'ECDC, 2015) ma anche Campylobacter lari, Campylobacter fetus e Campylobacter upsaliensis sono in grado di causare infezioni umane (EFSA, 2006). Campylobacter è frequentemente isolato nel tratto intestinale del pollame; pertanto, il consumo e la manipolazione di carne di pollame cruda o poco cotta

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Keshavamurthy, Nishanth, and Venkatesh Akshay Narsipur. "A new approach to purchasing of antibiotics for the Swedish system : A Cost-Benefit Analysis of centralized purchasing." Thesis, Uppsala universitet, Industriell teknik, 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-423294.

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The fast-increasing issue of antibiotic unavailability or relatively their shortages in the healthcare system has been the point of concern for many countries. With these shortages come unnecessary costs and the need to utilize less optimal treatment thus increasing the risk of antimicrobial resistance and jeopardizing a patient’s health. This thesis is a collaboration with PLATINEA (Platform for Innovation of Existing Antibiotics), aiming to optimize the usage of antibiotics and to increase the availability of important antibiotics in Sweden. To understand the causes that affect antibiotic un

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Silva, Ana Theriaga Gonçalves Gomes da. "Contribuição para o estudo da resistência antimicrobiana na infeção do trato respiratório inferior no cão e no gato." Master's thesis, Universidade de Lisboa, Faculdade de Medicina Veterinária, 2019. http://hdl.handle.net/10400.5/18949.

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Dissertação de Mestrado Integrado em Medicina Veterinária<br>A eficácia da utilização de antibióticos no tratamento de infeções enfrenta atualmente desafios associados ao aparecimento e disseminação de diferentes mecanismos de resistência antimicrobiana nos microrganismos. Por outro lado, as infeções bacterianas do trato respiratório inferior são afeções que podem colocar em risco a vida dos animais, sendo um diagnóstico clínico comum em cães e gatos. O objetivo do presente estudo foi contribuir para a caracterização da infeção bacteriana do trato respiratório inferior no cão e no gato e

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Correia, Joana Garcia. "Plano para redução do uso de antibióticos intramamários de secagem em explorações leiteiras nos Açores (São Miguel)." Master's thesis, Universidade de Lisboa, Faculdade de Medicina Veterinária, 2018. http://hdl.handle.net/10400.5/16441.

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Dissertação de Mestrado Integrado em Medicina Veterinária<br>Numa exploração leiteira, os períodos em que as vacas estão mais suscetíveis a infeções intramamárias são o período seco e o pós-parto. Para se controlar esses dois períodos o método utilizado na secagem é um ponto muito importante. Face ao aumento das resistências aos antimicrobianos (RAM) é cada vez mais necessário implementar o método seletivo de secagem. Para a seleção dos tratamentos na secagem utilizam-se técnicas como a contagem de células somáticas (CCS), o teste californiano de mastites (TCM), a cultura bacteriológica, entre

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Silva, Ana Cristina Marques da. "Microbiota e colorectal cancer: a preliminary study in Portuguese patients." Master's thesis, Universidade de Aveiro, 2017. http://hdl.handle.net/10773/21959.

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Mestrado em Microbiologia<br>The colorectal cancer (CRC) is the third deadly cancer in the world, and in the last years its incidence rate has been increasing in Portugal. Given the relevance of the symbiosis between the intestinal microbiota and the host for body homeostasis, many studies have been focusing on the analysis of the microbiota associated with health and disease scenarios, namely with CRC. It is increasingly more important to know the microbial community associated with CRC, once it can be exploited as a tool for different clinical applications against CRC. As such, the p

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Pinto, Flávio Miguel do Carmo. "Alternativas aos antibióticos químicos convencionais: estado-da-arte." Master's thesis, [s.n.], 2013. http://hdl.handle.net/10284/3984.

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Projeto de Pós-Graduação/Dissertação apresentado à Universidade Fernando Pessoa como parte dos requisitos para obtenção do grau de Mestre em Ciências Farmacêuticas<br>Com a fácil transferência das bactérias quer nos cuidados hospitalares, quer a nível comunitário, com o aumento do número de pessoas a necessitar de cuidados de saúde provocado pelo envelhecimento populacional, com o aumento do número de infeções associadas aos cuidados de saúde, com as viagens internacionais ao dispor de qualquer cidadão, com o uso irracional e exagerado dos antibióticos por parte da população e em explorações a

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Ribeiro, Vinicius Buccelli. "Caracterização de determinantes de virulência, integrons classe 1 e genes para resistência a antimicrobianos de cepas de Salmonella enterica isoladas de alimentos e fontes relacionadas." Universidade de São Paulo, 2007. http://www.teses.usp.br/teses/disponiveis/9/9131/tde-07112017-103827/.

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Salmonella é um dos mais importantes patógenos causadores de enfermidades transmitidas por alimentos (ETA) no Brasil e em outros países. Devido ao surgimento de fenótipos multi-resistentes (MOR) a agentes antimicrobianos em Salmonella, a caracterização dos genes envolvidos neste processo, sua localização e diversidade são importantes para identificação e compreensão dos fatores envolvidos na resistência. O objetivo deste trabalho foi caracterizar determinantes genéticos de virulência, resistência e integrons classe 1 presentes em cepas de diferentes sorotipos de Salmonella enterica multi-resis

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Monteiro, Sérgio Henrique. "Ocorrência de antibióticos e estudo de resistência microbiana em sistemas aquaculturais do Rio Paraná, Reservatório de Ilha Solteira, na região de Santa Fé do Sul, estado de São Paulo." Universidade de São Paulo, 2014. http://www.teses.usp.br/teses/disponiveis/64/64135/tde-06112014-104508/.

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A aquicultura teve um aumento significativo em todo o mundo nos últimos anos. Muitas classes de antimicrobianos são usadas na aquicultura para o tratamento de infecções causadas por bactérias patogênicas. Entretanto, a contaminação do ambiente, do alimento e a ocorrência de resistência microbiana decorrentes da intensa utilização dos antimicrobianos são motivos de preocupação. Com o objetivo de se saber a ocorrência de antimicrobianos e possíveis formação de resistência microbiana em pisciculturas paulistas, um método rápido, sensível e simples de extração em fase sólida acoplada à cromatograf

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Otto, Simon James Garfield. "ANTIMICROBIAL RESISTANCE OF HUMAN CAMPYLOBACTER JEJUNI INFECTIONS FROM SASKATCHEWAN." Thesis, 2011. http://hdl.handle.net/10214/2658.

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Saskatchewan is the only province in Canada to have routinely tested the antimicrobial susceptibility of all provincially reported human cases of campylobacteriosis. From 1999 to 2006, 1378 human Campylobacter species infections were tested for susceptibility at the Saskatchewan Disease Control Laboratory using the Canadian Integrated Program for Antimicrobial Resistance Surveillance panel and minimum inhibitory concentration (MIC) breakpoints. Of these, 1200 were C. jejuni, 129 were C. coli, with the remaining made up of C. lari, C. laridis, C. upsaliensis and undifferentiated Campylobacter s

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