Academic literature on the topic 'Benzodiazepines'

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Journal articles on the topic "Benzodiazepines"

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Nsira, Asma, Ahlem Karoui, Rafik Gharbi, and Moncef Msaddek. "Chemoselectivity of the 1,3-Dipolar Cycloaddition of Some Diazoalkanes with 1,5-Benzodiazepine Derivatives." Journal of Chemical Research 36, no. 3 (2012): 152–56. http://dx.doi.org/10.3184/174751912x13300109535030.

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Benzodiazepines are pharmaceutically important synthetic materials. Reaction of the 4-(2-hydroxyphenyl)-1,5-benzodiazepin-2-one with 2-diazopropane (DAP) gave a mixture of the 2-isopropylether of 4-(2-hydroxyphenyl)-3H-1,5-benzodiazepine and 1-isopropyl-4-(2-hydroxyphenyl)-3H-1,5-benzodiazepin-2-one. Whilst diphenyldiazomethane (DPDM) gave 1-benzhydryl-4-(2-hydroxyphenyl)-3H-1,5-benzodiazepin-2-one. Reaction of the corresponding thione with DAP led to the 2-isopropylthioether of 4-(2-hydroxyphenyl)-3H-1,5-benzodiazepine and 1-isopropyl-4-(2-hydroxyphenyl)-1,5-benzodiazepine-2-thione while the
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Rotaru, Luciana Teodora, Paul Nedelea, Renata-Maria Varut, et al. "Determining the Influence of Alcohol on the Pharmacological Effect of Benzodiazepines by Molecular Docking Tehnique." Revista de Chimie 70, no. 3 (2019): 814–19. http://dx.doi.org/10.37358/rc.19.3.7013.

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Benzodiazepines represents a large category of medications that were originally developed to treat anxiety disorders or issues with anxiety, seizures, and issues with sleeping. The most common drugs abused along with benzodiazepines are other benzodiazepines, prescription pain medications and alcohol. Alcohol and benzodiazepine have a synergistic depressant effect on the central nervous system. Combining alcohol with benzodiazepines can be dangerous practice even if it is engaged in only occasionally. In the present study, using molecular docking technique we followed the binding energy of ben
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Kim, Yoseop, та Sung-Gon Kim. "Stereoselective [4+3]-Cycloaddition of 2-Amino-β-Nitrostyrenes with Azaoxyallyl Cations to Access Functionalized 1,4-Benzodiazepin-3-Ones". Molecules 29, № 6 (2024): 1221. http://dx.doi.org/10.3390/molecules29061221.

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The 1,4-benzodiazepine structural framework is a fascinating element commonly found in biologically active and pharmaceutically relevant compounds. A highly efficient method for synthesizing 1,4-benzodiazepin-3-ones is described, involving a [4+3]-cycloaddition reaction between 2-amino-β-nitrostyrenes and α-bromohydroxamate, with Cs2CO3 used as a base. This process yielded the desired 1,4-benzodiazepines in good yields. Furthermore, an organocatalytic asymmetric [4+3]-cycloaddition was successfully accomplished using a bifunctional squaramide-based catalyst. This approach enabled the enantiose
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Okulevičiūtė, Agnė, and Gabija Laubner Sakalauskienė. "Narrative Literature Review of Potential Atrial Fibrillation Mechanism of Action Induced by Discontinuation of Benzodiazepines." Acta medica Lituanica 30, no. 2 (2023): 14. http://dx.doi.org/10.15388/amed.2023.30.2.14.

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Introduction: Benzodiazepines are commonly prescribed but often misused, leading to dependence and withdrawal symptoms. Increased worldwide prescriptions raise adverse effects and overdose concerns, especially for the elderly. Caution is needed in prescribing and considering alternative treatments to minimize risks. Aim: Narrative literature review of potential atrial fibrillation mechanism of action induced by discontinuation of benzodiazepines. Materials and methods: Database PubMed was searched using the combination of keywords – “Benzodiazepine AND atrial fibrillation OR peripheral benzodi
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Summers, J., and K. W. Brown. "Benzodiazepine prescribing in a psychiatric hospital." Psychiatric Bulletin 22, no. 8 (1998): 480–83. http://dx.doi.org/10.1192/pb.22.8.480.

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Using a case note study, this paper presents a longitudinal survey of the effect of psychiatric inpatient care on benzodiazepine prescribing. Standards were proposed to assess the quality of this prescribing. Based on these standards, the study shows inappropriate use of benzodiazepines. Following admission, there was an increase in the number of patients prescribed benzodiazepines and in the number of benzodiazepines prescribed. Of the benzodiazepines withdrawn, most were contrary to the proposed standard. The quality of drug history showed little emphasis being placed on rationalising benzod
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Muzaale, Abimereki D., Matthew Daubresse, Sunjae Bae, et al. "Benzodiazepines, Codispensed Opioids, and Mortality among Patients Initiating Long-Term In-Center Hemodialysis." Clinical Journal of the American Society of Nephrology 15, no. 6 (2020): 794–804. http://dx.doi.org/10.2215/cjn.13341019.

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Background and objectivesMortality from benzodiazepine/opioid interactions is a growing concern in light of the opioid epidemic. Patients on hemodialysis suffer from a high burden of physical/psychiatric conditions, which are treated with benzodiazepines, and they are three times more likely to be prescribed opioids than the general population. Therefore, we studied mortality risk associated with short- and long-acting benzodiazepines and their interaction with opioids among adults initiating hemodialysis.Design, setting, participants, & measurementsThe cohort of 69,368 adults initiating h
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Reid Finlayson, Alistair J., Jane Macoubrie, Christy Huff, D. E. Foster, and Peter R. Martin. "Experiences with benzodiazepine use, tapering, and discontinuation: an Internet survey." Therapeutic Advances in Psychopharmacology 12 (January 2022): 204512532210823. http://dx.doi.org/10.1177/20451253221082386.

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Background: Over 92 million prescriptions for benzodiazepines are dispensed in the United States annually, yet little is known about the experiences of those taking and discontinuing them. Objective: The aim of this study is to assess the experiences of those taking, tapering, or having discontinued benzodiazepines. Methods: An online survey ( n = 1207) elicited information about benzodiazepine use, including long-term use, tapering, discontinuation, and withdrawal symptoms. Results: Symptoms associated with benzodiazepine use, tapering, and discontinuation were numerous and ranged from sympto
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Raut, Binod, Anjan Khadka, Pradeep Manandhar, and Kamal Kandel. "Study of association between characteristics of patient and likelihood of benzodiazepine use in psychiatry outpatient department at tertiary care hospital of Kathmandu." Journal of Chitwan Medical College 7, no. 3 (2017): 13–20. http://dx.doi.org/10.3126/jcmc.v7i3.23689.

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Introduction: Benzodiazepines exert their pharmacological properties as hypnotics, anxiolytics, anticonvulsants and muscle relaxants. Benzodiazepines are clinically effective for a number of indication including the reduction of anxiety, the induction and maintenance of sleep, muscle relaxation. They have a range of well documented adverse effects that may outweigh the benefits in certain patient population including psychomotor impairment, development of tolerance and dependence, potential for abuse. 
 Methods: It is a hospital based prospective cross-sectional study conducted in a psych
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Hamed, Othman, Oswa Fares, Shaima Taleeb, et al. "New Insights Towards 1,4-Benzodiazepines from Curcumin. Design, Synthesis and Antimicrobial Activities." Medicinal Chemistry 16, no. 8 (2020): 1112–23. http://dx.doi.org/10.2174/1573406415666190826160251.

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Background: Curcumin is a safe, versatile natural product with unlimited number of biological activities and a precursor for various heterocyclic compounds. Objective: The present study was aimed to the development of a curcumin based antimicrobial reagent with high potency against gram-positive and gram-negative bacteria. Methods: Herein we report a simple and convenient one step method for synthesizing a series of 1,4-benzodiazepines via condensation cyclization reaction between curcumin and various 1,2- phenylenediamine in refluxed ethanol. Results: A series of new 1,4-benzodiazepins were s
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Bužančić, Iva, Tajana Iva Pejaković, and Maja Ortner Hadžiabdić. "A Need for Benzodiazepine Deprescribing in the COVID-19 Pandemic: A Cohort Study." Pharmacy 10, no. 5 (2022): 120. http://dx.doi.org/10.3390/pharmacy10050120.

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The COVID-19 pandemic has had a negative impact on patients’ mental health. The aim of this study was to explore whether the pandemic influenced the use and prescription of benzodiazepines and increased the need for community pharmacist involvement in counselling on deprescribing. Electronic prescription-related data from one pharmacy in Croatia were retrospectively collected for the COVID-19 period (April 2020 to March 2021) and compared with pre-COVID-19 (April 2019 to March 2020) data. Data were collected for patients diagnosed with anxiety disorders who filled out more than one prescriptio
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Dissertations / Theses on the topic "Benzodiazepines"

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Rizzo, Michael L. "The Prescribing Knowledge, Attitudes, and Practices among Nurse Practitioners in Maine towards Benzodiazepines." Fogler Library, University of Maine, 2004. http://www.library.umaine.edu/theses/pdf/RizzoML2004.pdf.

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Riond, Joëlle. "Benzodiazepines peripheriques." Lyon, INSA, 1990. http://www.theses.fr/1990ISAL0094.

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Les benzodiazépines sont sédatives, anxiolytiques et anti-convulsantes. Leurs s'exercent par l'intermédiaire de récepteurs dans le système nerveux central. Cependant, certaines benzodiazépines se fixent aussi sur un récepteur pharmacologiquement distinct (BPBS), dans les organes périphériques. Celui-ci semble être impliqué dans l'immuno-modulation : nous avons observé un effet des benzodiazépines périphériques sur la prolifération lymphocytaire in vitro. Afin de caractériser le récepteur de ces ligands, nous l'avons purifié à partir de la l ignée cellulaire CHO (hamster), puis clivé, pour en d
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Bentes, Ana Paula Guerreiro 1985. "Estudo comparativo dos efeitos do alprazolam e midazolam no controle da ansiedade em implantodontia." [s.n.], 2012. http://repositorio.unicamp.br/jspui/handle/REPOSIP/290773.

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Orientador: Eduardo Dias de Andrade<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Odontologia de Piracicaba<br>Made available in DSpace on 2018-08-20T06:28:38Z (GMT). No. of bitstreams: 1 Bentes_AnaPaulaGuerreiro_M.pdf: 1168135 bytes, checksum: ca31fffb62b345249aeec51b5df67d0c (MD5) Previous issue date: 2012<br>Resumo: A sedação mínima deve ser considerada como parte do protocolo farmacológico nas cirurgias implantodônticas, já que os pacientes podem apresentar um grau aumentado de ansiedade, interrompendo o curso da intervenção, entre outras possíveis intercorr
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SEROR, PAULE-MICHELE. "Les antagonistes des benzodiazepines." Lyon 1, 1989. http://www.theses.fr/1989LYO1M257.

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DEFOUR, ERIC. "Reactions cutanees aux benzodiazepines." Université Louis Pasteur (Strasbourg) (1971-2008), 1992. http://www.theses.fr/1992STR1M132.

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NICOLAI, LAURENT. "Effets amnesiants des benzodiazepines." Strasbourg 1, 1992. http://www.theses.fr/1992STR15003.

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Guenoux, Charles-Albert. "Benzodiazepines : aspects pharmacologiques actuels." Aix-Marseille 2, 1990. http://www.theses.fr/1990AIX20952.

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MOUSSY, HUBERT CORINNE. "Etudes psychometriques des benzodiazepines." Nantes, 1992. http://www.theses.fr/1992NANT042M.

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Braun, Ivan Mario. "Potencial de abuso do midazolam intranasal em usuários de cocaína aspirada e voluntários normais." Universidade de São Paulo, 2012. http://www.teses.usp.br/teses/disponiveis/5/5142/tde-28112012-124456/.

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INTRODUÇÃO: O midazolam é uma imidazobenzodiazepina usada para induzir o sono, produzir sedação antes de procedimentos dolorosos e no tratamento do estado de mal epiléptico. Seu uso pela via intranasal proporciona um rápido início de ação e esta via, em muitos casos, pode substituir as vias endovenosa e intramuscular, mais invasivas. Assim, o midazolam intranasal tem sido sugerido no tratamento extra-hospitalar de crises epilépticas e ataques de pânico. Por outro lado, os benzodiazepínicos possuem um potencial para serem abusados, principalmente em usuários de outras drogas. OBJETIVO: o presen
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STITI, SALADIN. "Les benzodiazepines et leurs paradoxes." Toulouse 3, 1988. http://www.theses.fr/1988TOU31061.

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Books on the topic "Benzodiazepines"

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R, Trimble Michael, and Hindmarch I. 1944-, eds. Benzodiazepines. Wrightson Biomedical Pub., 2000.

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Lacey, Ron. That's life! survey on tranquillisers. British Broadcasting Corporation in association with MIND, 1985.

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1944-, Hindmarch I., ed. Benzodiazepines: Current concepts : biological, clinical, and social perspectives. Wiley, 1990.

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Schütz, Harald. Benzodiazepines II. Springer Berlin Heidelberg, 1989. http://dx.doi.org/10.1007/978-3-642-74031-2.

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Network, Drug Abuse Warning, National Institute on Drug Abuse. Division of Epidemiology and Statistical Analysis., and CSR Incorporated, eds. A Decade of DAWN: Benzodiazepine-related cases, 1976-1985 : topical data from the Drug Abuse Warning Network. U.S. Dept. of Health and Human Services, Public Health Service, Alcohol, Drug Abuse, and Mental Health Administration, National Institute on Drug Abuse, Division of Epidemiology and Statistical Analysis, 1988.

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Ivan, Izquierdo, and Medina Jorge, eds. Naturally occurring benzodiazepines: Structure, distribution, and function. Ellis Horwood, 1993.

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Salamone, Salvatore J. Benzodiazepines and GHB. Humana Press, 2001. http://dx.doi.org/10.1385/1592591094.

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Salamone, Salvatore J., ed. Benzodiazepines and GHB. Humana Press, 2001. https://doi.org/10.1007/978-1-59259-109-1.

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F, Squires Richard, ed. GABA and benzodiazepine receptors. CRC Press, 1988.

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Gudex, Claire. Adverse effects of benzodiazepines. Centre for Health Economics, University of York, 1990.

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Book chapters on the topic "Benzodiazepines"

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Netzel, Christopher L., and Alaa Abd-Elsayed. "Benzodiazepines." In Pain. Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-319-99124-5_63.

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Tschanz, Joann T., and Katherine Treiber. "Benzodiazepines." In Encyclopedia of Clinical Neuropsychology. Springer New York, 2011. http://dx.doi.org/10.1007/978-0-387-79948-3_1759.

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Kim, David J., and Srdjan S. Nedeljkovic. "Benzodiazepines." In Pain Medicine. Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-43133-8_46.

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Tschanz, JoAnn. "Benzodiazepines." In Encyclopedia of Clinical Neuropsychology. Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-56782-2_1759-3.

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Jufer-Phipps, Rebecca A., and Barry S. Levine. "Benzodiazepines." In Principles of Forensic Toxicology. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-42917-1_20.

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Tschanz, JoAnn. "Benzodiazepines." In Encyclopedia of Clinical Neuropsychology. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-57111-9_1759.

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Allgulander, Christer, and David Nutt. "Benzodiazepines." In Encyclopedia of Psychopharmacology. Springer Berlin Heidelberg, 2015. http://dx.doi.org/10.1007/978-3-642-36172-2_113.

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Tyrer, Peter J., Mark Slifstein, Joris C. Verster, et al. "Benzodiazepines." In Encyclopedia of Psychopharmacology. Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/978-3-540-68706-1_113.

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Nielsen, Suzanne. "Benzodiazepines." In Non-medical and illicit use of psychoactive drugs. Springer International Publishing, 2015. http://dx.doi.org/10.1007/7854_2015_425.

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Wilson, John Fawcett. "Benzodiazepines." In The Immunoassay Kit Directory. Springer Netherlands, 1995. http://dx.doi.org/10.1007/978-94-011-0679-5_59.

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Conference papers on the topic "Benzodiazepines"

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Lehfeld, Letícia D'Agostino, and Camila Tavares Valadares da Silva. "Comparative analysis of z-hypnotics and benzodiazepines for insomnia." In III Seven International Medical and Nursing Congress. Seven Congress, 2024. http://dx.doi.org/10.56238/iiicongressmedicalnursing-006.

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The Brazilian population has a 72% incidence of sleep disorders, the main one being insomnia. Furthermore, the use of z-hypnotics increased by 73% among Brazilians from 2019 to 2021. Based on this, this study aims to conduct a bibliographic review on the use of z-hypnotics, such as zolpidem and eszopiclone, and their repercussions compared to benzodiazepines. As a methodology, scientific articles from SciELO, Revista Neurociências, Revista Brasileira de Psiquiatria and Revista Brasileira de Neurologia cataloged in recent years were used. As a result, it was found that the use of benzodiazepine
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Hirschfeld, Robert M. A. "STRATEGIES FOR PRESCRIBING BENZODIAZEPINES." In IX World Congress of Psychiatry. WORLD SCIENTIFIC, 1994. http://dx.doi.org/10.1142/9789814440912_0205.

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Doane, Eric. "Isolated Temazepam Overdose: A Unique Case of an Unresponsive Female." In 27th Annual Rowan-Virtua Research Day. Rowan University Libraries, 2023. https://doi.org/10.31986/issn.2689-0690_rdw.stratford_research_day.106_2023.

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Cases of acute overdose presenting to the emergency department pose a great challenge given that history can sometimes be limited or at times be inaccurate. While naloxone is routinely given in the field to help reduce opiate’s sedating effects, the routine use of flumazenil has not been routinely adopted in cases of benzodiazepine overdose. This is because, unlike naloxone, there are many medications that act on the GABA receptor, and flumazenil is only specific for binding to the benzodiazepine/GABA receptor. This can lead to an unmasking of other medications that may be co-ingested that als
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KALES, ANTHONY, ALEXANDROS N. VGONTZAS, and EDWARD O. BIXLER. "NOT ALL BENZODIAZEPINES ARE ALIKE: UPDATE 1993." In IX World Congress of Psychiatry. WORLD SCIENTIFIC, 1994. http://dx.doi.org/10.1142/9789814440912_0203.

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Gayen, S., G. Carbell, N. Kaur, et al. "Phenobarbital Can Reduce Intensive Care Unit Length of Stay in Patients With Alcohol/Benzodiazepine Withdrawal as Compared to Benzodiazepines." In American Thoracic Society 2023 International Conference, May 19-24, 2023 - Washington, DC. American Thoracic Society, 2023. http://dx.doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a2595.

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Sirbu, Rodica. "CONTROL OF BENZODIAZEPINES TESTED THROUGH MODERN PHYSICOCHEMICAL METHODS." In 2nd International Multidisciplinary Scientific Conference on Social Sciences and Arts SGEM2015. Stef92 Technology, 2015. http://dx.doi.org/10.5593/sgemsocial2015/b11/s2.047.

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RYDBERG, ULF. "BENZODIAZEPINES - LONG TERM USE, SIDE EFFECTS AND DEPENDENCY." In IX World Congress of Psychiatry. WORLD SCIENTIFIC, 1994. http://dx.doi.org/10.1142/9789814440912_0210.

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Rayner, Samuel G., Stacy Jepsen, Helen Peng, and Alain F. Broccard. "Dexmedetomidine To Treat Severe Alcohol Withdrawal Refractory To Benzodiazepines." In American Thoracic Society 2011 International Conference, May 13-18, 2011 • Denver Colorado. American Thoracic Society, 2011. http://dx.doi.org/10.1164/ajrccm-conference.2011.183.1_meetingabstracts.a4721.

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Mojsoska, Snezana. "The Usage Of Benzodiazepines By Medically Educated Persons In Macedonia." In 2nd Central and Eastern European LUMEN International Conference - Multidimensional Education and Professional Development. Ethical Values. Cognitive-crcs, 2017. http://dx.doi.org/10.15405/epsbs.2017.07.03.52.

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Watson, PL, PA Howard, KC Vigil, et al. "Benzodiazepines Are Associated with "Atypical" Sleep in Critically Ill Patients." In American Thoracic Society 2009 International Conference, May 15-20, 2009 • San Diego, California. American Thoracic Society, 2009. http://dx.doi.org/10.1164/ajrccm-conference.2009.179.1_meetingabstracts.a1599.

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Reports on the topic "Benzodiazepines"

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Peng, ciyan, Sini Li, Jing Chen, et al. The Clinical Efficacy and Safety of Sixteen CPMs in Combination with Benzodiazepines/Non-Benzodiazepines for Chronic Adult Insomnia: A Multiple-Treatments Meta-Analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2023. http://dx.doi.org/10.37766/inplasy2023.3.0020.

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Li, Qu, Xue-Ping Ma, Alimujiang Simayi, Xiao-Li Wang, and Gui-Ping Xu. Comparative efficacy of various pharmacologic treatments of alcohol withdrawal syndrome: A systematic review and network meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2021. http://dx.doi.org/10.37766/inplasy2021.12.0010.

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Review question / Objective: Lorazepam and other benzodiazepines (BZDs) are considered the first choice for treatment of Alcohol withdrawal syndrome (AWS). But they have significant addiction potential and can cause fatal respiratory depression if used in large doses. The aim of our study is to conduct a network meta-analysis to provide some data support for the clinical treatment of AWS. The patients were persons with alcohol withdrawal. The intervention being studied must be a comparison of the efficacy of the two pharmacologic treatments. The study should not be included if two pharmacologi
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Marczynski, Thaddeus J. Attention Span, Anxiety and Benzodiazepine Receptors. Defense Technical Information Center, 1991. http://dx.doi.org/10.21236/ada234549.

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Papadopoulos, Vassilios. Peripheral Benzodiazepine Receptor in Human Breast Cancer. Defense Technical Information Center, 2002. http://dx.doi.org/10.21236/ada405505.

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Papadopoulas, Vassilios. Peripheral Benzodiazepine Receptor (PBR) in Human Breast Cancer. Defense Technical Information Center, 2003. http://dx.doi.org/10.21236/ada420939.

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Lee, Jenna. Effects of Long-Term Benzodiazepine Use on Cognitive Testing. Iowa State University, 2021. http://dx.doi.org/10.31274/cc-20240624-599.

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Campbell, Tonya, Siyu Men, Gurnoor Brar, et al. Characterizing Prescription Benzodiazepine Use among Community-Dwelling Residents of Ontario, Canada. ODPRN, 2021. http://dx.doi.org/10.31027/odprn.2021.01.

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Das, Salil K. Is Peripheral Benzodiazepine Receptor (PBR) Gene Expression Involved in Breast Cancer Suppression by Dietary Soybean Protein. Defense Technical Information Center, 2005. http://dx.doi.org/10.21236/ada436892.

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Das, Salil. Is Peripheral Benzodiazepine Receptor (PBR) Gene Expression Involved in Breast Cancer Suppression by Dietary Soybean Protein? Defense Technical Information Center, 2006. http://dx.doi.org/10.21236/ada457465.

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Viswanathan, Meera, Jennifer Cook Middleton, Alison Stuebe, et al. Maternal, Fetal, and Child Outcomes of Mental Health Treatments in Women: A Systematic Review of Perinatal Pharmacologic Interventions. Agency for Healthcare Research and Quality (AHRQ), 2021. http://dx.doi.org/10.23970/ahrqepccer236.

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Background. Untreated maternal mental health disorders can have devastating sequelae for the mother and child. For women who are currently or planning to become pregnant or are breastfeeding, a critical question is whether the benefits of treating psychiatric illness with pharmacologic interventions outweigh the harms for mother and child. Methods. We conducted a systematic review to assess the benefits and harms of pharmacologic interventions compared with placebo, no treatment, or other pharmacologic interventions for pregnant and postpartum women with mental health disorders. We searched fo
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