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1

Ohseto, Kiyoshige, Hiroyuki Uchino, and Hiroki Iida, eds. Nerve Blockade and Interventional Therapy. Springer Japan, 2019. http://dx.doi.org/10.1007/978-4-431-54660-3.

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2

1939-, Cousins Michael J., and Bridenbaugh Phillip O. 1932-, eds. Neural blockade in clinical anesthesia andmanagement of pain. 2nd ed. Lippincott, 1988.

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3

J, Cousins Michael, and Bridenbaugh Phillip O. 1932-, eds. Neural blockade in clinical anesthesia and management of pain. 2nd ed. Lippincott, 1988.

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4

J, Cousins Michael, and Bridenbaugh Phillip O. 1932-, eds. Neural blockade in clinical anesthesia and management of pain. 3rd ed. Lippincott-Raven, 1998.

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5

Hebl, James R. Mayo Clinic atlas of regional anesthesia and ultrasound-guided nerve blockade. Edited by Mayo Foundation for Medical Education and Research. Mayo Clinic Scientific Press, 2010.

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6

Lennon, Robert L. Mayo Clinic analgesic pathway: Peripheral nerve blockade for major orthopedic surgery. Mayo Clinic Scientific Press, 2005.

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7

Lennon, Robert L. Mayo Clinic analgesic pathway: Peripheral nerve blockade for major orthopedic surgery. Mayo Clinic Scientific Press, 2006.

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8

R, Hebl James, Lennon Robert L, and Mayo Foundation for Medical Education and Research., eds. Mayo Clinic atlas of regional anesthesia and ultrasound-guided nerve blockade. Oxford University Press ; New York : Mayo Scientific Press, 2010.

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9

R, Hebl James, Lennon Robert L, and Mayo Foundation for Medical Education and Research., eds. Mayo Clinic atlas of regional anesthesia and ultrasound-guided nerve blockade. Oxford University Press ; New York : Mayo Scientific Press, 2010.

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10

J, Cousins Michael, ed. Cousins and Bridenbaugh's neural blockade: In clinical anesthesia and management of pain. 4th ed. Lippincott Williams & Wilkins, 2009.

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11

Peripheral Nerve Blockade. Churchill Livingstone, 1997.

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12

Uchino, Hiroyuki, Kiyoshige Ohseto, and Hiroki Iida. Nerve Blockade and Interventional Therapy. Springer, 2019.

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13

Uchino, Hiroyuki, Kiyoshige Ohseto, and Hiroki Iida. Nerve Blockade and Interventional Therapy. Springer, 2016.

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14

Uchino, Hiroyuki, Kiyoshige Ohseto, and Hiroki Iida. Nerve Blockade and Interventional Therapy. Springer, 2015.

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15

Stockman, Joel, and Lisa Lee. Peripheral Nerve Blockade in the Pediatric Patient. Edited by Kirk Lalwani, Ira Todd Cohen, Ellen Y. Choi, and Vidya T. Raman. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190685157.003.0056.

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Peripheral nerve blockade among the pediatric and adult population has seen continuous growth over the past decade. Improvements in ultrasonography and proven safety with minimal complications further the utilization of upper and lower extremity blockade. Procedures can safely be completed under general anesthesia in the pediatric patient. Catheters can be left in place to prolong blockade, allowing the patient to decrease narcotic pain medication for longer time periods. Contraindications include patient refusal, coagulopathy, and local infection. Continuous peripheral nerve blocks deliver pr
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16

Tumber, Paul Singh, and Philip W. H. Peng. Peripheral Nerve Blocks in Chronic Pain. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199908004.003.0037.

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Ultrasound-guided nerve blockade for chronic pain offers advantages over blind landmark-based and fluoroscopic techniques. It allows visualization of soft-tissue structures and spread of the injectate while limiting ionizing radiation exposure. Interventionalists must have both a clear understanding of the anatomy that is being visualized on the ultrasound image and the ability to safely place a needle to the desired target site. Neural blockade of the suprascapular nerve can be useful in the management of chronic shoulder pain such as adhesive capsulitis, frozen shoulder, rotator cuff tear, a
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17

Ludwig, Aleksandra. Die Blockade des Nervus obturatorius bei der transurethralen Resektion von Blasentumoren. 1990.

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18

Hebl, James, and Robert Lennon. Mayo Clinic Atlas of Regional Anesthesia and Ultrasound-Guided Nerve Blockade. Oxford University Press, 2010. http://dx.doi.org/10.1093/med/9780199743032.001.0001.

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Mayo Clinic Atlas of Regional Anesthesia and Ultrasound-Guided Nerve Blockade is a practical guide for residents-in-training and clinicians to gain greater familiarity with regional anesthesia and acute pain management to the upper and lower extremity. It emphasizes the importance of a detailed knowledge of applied anatomy to safely and successfully performing regional anesthesia. It also provides and overview of the emerging field of ultrasound-guided regional anesthesia, which allows reliable identification of both normal and variant anatomy. Mayo Clinic Atlas of Regional Anesthesia and Ultr
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19

Lennon, Robert L., and Terese T. Horlocker. Mayo Clinic Analgesic Pathway: Peripheral Nerve Blockade for Major Orthopedic Surgery. Taylor & Francis Group, 2005.

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20

Lennon, Robert L., and Terese T. Horlocker. Mayo Clinic Analgesic Pathway: Peripheral Nerve Blockade for Major Orthopedic Surgery. Taylor & Francis Group, 2017.

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21

Mayo Clinic Analgesic Pathway: Peripheral Nerve Blockade for Major Orthopedic Surgery. Informa Healthcare, 2005.

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22

Prentice, Elizabeth. Peripheral Nerve Block Catheter for Extremity Surgery. Oxford University Press, 2013. http://dx.doi.org/10.1093/med/9780199764495.003.0060.

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Continuous peripheral nerve blockade (CPNB) can provide excellent postoperative analgesia. Many adult studies report the effectiveness of CPNB. Although not as widely adopted in pediatrics, several studies support its use. Its niche lies in provision of analgesia after major unilateral limb surgery with severe postoperative pain expected for 48 to 72 hours. Lower limb surgery of this type is more common than upper limb in the pediatric population. Examples include club foot repair, osteotomy, or resection of sarcoma. This chapter presents two cases where CPNB is a good option for postoperative
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23

Lipov, Eugene. Role of the Sympathetic Nervous System in Post-Traumatic Stress Disorder–Related Male Sexual Dysfunction. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780190461508.003.0003.

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This chapter reviews recent literature related to local anesthetic sympathetic ganglion blockade (SGB) in treatment of post-traumatic stress disorder (PTSD) and its effect on the overall function of patients, with specific emphasis on male sexual and marital function. This chapter also discusses a publically available video in which a patient who had the PTSD checklist (PCL) administered before, and following, SGB as well as his wife were interviewed. A 34 year-old male Army Ranger veteran who suffered severe PTSD with associated marital and sexual difficulties after deployment, the patient ha
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24

Hunter, Jennifer M., and Thomas Fuchs-Buder. Neuromuscular blockade and reversal. Edited by Michel M. R. F. Struys. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199642045.003.0016.

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Over the past 70 years since the introduction of d-tubocurarine, the search for an ideal neuromuscular blocking agent has led to the development of the depolarizing drug, succinylcholine (suxamethonium), with its rapid onset of action and plasma metabolism, and a series of non-depolarizing agents of which there are two groups: benzylisoquinoliniums (e.g. atracurium, cisatracurium and mivacurium) and aminosteroidal agents (e.g. pancuronium, vecuronium and rocuronium). The need to monitor neuromuscular block perioperatively to ensure the appropriate dose of any neuromuscular blocking drug is giv
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25

Gupta, Rajnish K., and Alexandria N. Nickless. Nerve Injuries from Positioning and Regional Blocks. Edited by Matthew D. McEvoy and Cory M. Furse. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190226459.003.0074.

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Peripheral nerve injury in the perioperative period can have a variety of etiologies, including preexisting patient factors and by surgical and anesthetic complications such as intraoperative positioning and nerve blockade. The actual incidence may be difficult to assess, because most nerve injuries resolve with time and frequently require minimal to no intervention. Injuries often manifest more than 48 hours after surgery and have even been noted in patients who undergo awake procedures and in hospitalized patients who never undergo surgery. This should not negate the fact that close attentio
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26

Jamison, David, Indy Wilkinson, and Steven P. Cohen. Facet Joint Interventions: Fluoroscopy. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199908004.003.0019.

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This chapter reviews the diagnosis and treatment of facet joint pain. Fluoroscopic guidance is commonly used to optimize treatment outcomes. The only reliable way to identify a painful facet joint is with image-guided blockade of either the medial branch innervating the joint or the joint itself. Although computed tomography (CT) and ultrasound have been shown to provide reliable landmarks for accurate needle placement, these modalities have limitations. The risks of CT include increased radiation exposure, cost, and an inability to perform real-time contrast injection. While ultrasound provid
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27

Missler, Bernhard Nikolaus. Blockadegrad und Methämoglobinbildung bei der kombinierten Nervus Ischiadicus-3-in-1-Blockade mit Prilocain. 1995.

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28

Phillips, Alistair, and Harry Akerman. Anaesthesia. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198757689.003.0003.

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Pain-free surgery can be imposed on the hand and wrist without resort to general anaesthetic. Options include local anaesthetic infiltration which can, in higher volumes mixed with adrenaline, allow surgery without a tourniquet. This technique (wide awake local anaesthetic without tourniquet or WALANT) permits the patient to move the fingers without the muscle paralysis induced by the regional anaesthetic and tourniquet, adding invaluable information, e.g. in tendon transfers. The efficacy of specific peripheral nerve blockade and brachial plexus block can be enhanced by ultrasound or nerve st
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29

Warwick, David, Roderick Dunn, Erman Melikyan, and Jane Vadher. Anaesthesia. Oxford University Press, 2011. http://dx.doi.org/10.1093/med/9780199227235.003.0003.

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Local and regional anaesthesia 88Pharmacology of local anaesthetics 88Toxicity of local anaesthetics 90Peripheral nerve blockade 92Regional anaesthesia 94Complications of regional anaesthesia 95Topical anaesthesia 95Tourniquet 96Local and regional anaesthesia is widely used in hand surgery due to its favourable attributes. These are mainly: ...
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30

Lennon, Robert L., and Terese T. Horlocker. Mayo Clinic Analgesic Pathway: Peripheral Nerve Blockade for Major Orthopedic Surgery and Procedural Training Manual. Taylor & Francis Group, 2006.

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31

Lennon, Robert L. Mayo Clinic Analgesic Pathway: Peripheral Nerve Blockade for Major Orthopedic Surgery and Procedural Training Manual. Taylor & Francis Group, 2006.

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32

Lennon, Robert L., and Terese T. Horlocker. Mayo Clinic Analgesic Pathway: Peripheral Nerve Blockade for Major Orthopedic Surgery and Procedural Training Manual. Taylor & Francis Group, 2006.

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33

Crum, Brian A., Eduardo E. Benarroch, and Robert D. Brown. Neurologic Disorders Categorized by Mechanism. Oxford University Press, 2012. http://dx.doi.org/10.1093/med/9780199755691.003.0524.

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Mechanisms of neurologic disease can be cerebrovascular, neoplastic, movement disorders, infectious diseases. The causes of ischemic cerebrovascular disorders can be classified on the basis of the site of the source for the arterial blockage within the vascular system, from most proximal to distal. The causes of ischemic cerebrovascular disorders, including transient ischemic attack and cerebral infarction, can be classified on the basis of the site of the source for the arterial blockage within the vascular system, from most proximal to distal. Tremor is an oscillatory rhythmic movement disor
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34

Dashfield, Adrian. Acute pain. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780198719410.003.0040.

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This chapter discusses the management of acute pain. It begins with an introduction which describes the benefits of acute pain management and the measurement of pain. Analgesic drugs are then described, including paracetamol, non-steroidal anti-inflammatory drugs, and opioids (including their comparative efficacy). Patient-controlled analgesia, epidural analgesia, and continuous peripheral nerve blockade are described. Transcutaneous electrical nerve stimulation and acupuncture are discussed. The management of the patient with a substance misuse disorder is discussed. The chapter concludes wit
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35

Dashfield, Adrian. Acute pain. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198719410.003.0040_update_001.

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This chapter discusses the management of acute pain. It begins with an introduction which describes the benefits of acute pain management and the measurement of pain. Analgesic drugs are then described, including paracetamol, non-steroidal anti-inflammatory drugs, and opioids (including their comparative efficacy). Patient-controlled analgesia, epidural analgesia, and continuous peripheral nerve blockade are described. Transcutaneous electrical nerve stimulation and acupuncture are discussed. The management of the patient with a substance misuse disorder is discussed. The chapter concludes wit
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36

Narouze, Samer N. Lumbar Sympathetic Block: Fluoroscopy. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199908004.003.0030.

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Lumbar sympathetic blocks (LSB) result in the interruption of the sympathetic efferent fibers to the lower extremities with sparing of the somatic nerves, thus providing a diagnostic value as to the relative sympathetic contribution to the patient’s pain syndrome. In those patients with significant sympathetically maintained pain, repeated blocks may provide a therapeutic value and help facilitate physical therapy. The original described technique is the paramedian or “classic” approach described by Mandl in 1926. A more lateral approach was later developed by Reid and colleagues. The incidenc
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37

Prout, Jeremy, Tanya Jones, and Daniel Martin. Nervous and musculoskeletal systems. Oxford University Press, 2014. http://dx.doi.org/10.1093/med/9780199609956.003.0006.

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This chapter outlines the basic science related to the nervous and musculoskeletal systems which particularly apply to the conduct of anaesthesia. Consciousness, sleep and anaesthetic depth are discussed with the measurement of anaesthetic depth using bispectral index and evoked potentials. Factors which influence cerebral blood flow and intracerebral pressure are detailed, allowing understanding of neuroanaesthesia techniques. Pharmacological and anaesthetic management of seizures is also described. Diseases affecting the autonomic nervous system, testing for these disorders and the implicati
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38

Mayo Clinic Analgesic Pathway: Peripheral Nerve Blockade for Major Orthopedic Surgery and Procedural Training Manual with DVD (Book + DVD set). Informa Healthcare, 2006.

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39

Stammen, Katherine, Harish Siddaiah, Cody Brechtel, Elyse M. Cornett, Charles J. Fox, and Alan D. Kaye. Pain Management for General Surgery. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190457006.003.0006.

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Pain is multidimensional and subjective, which makes it difficult to treat. Newer treatment modalities have been under development with a better understanding of pain pathways in recent years. These treatments take advantage of the multifactorial components of pain, including agents such as ketamine, capsaicin, gabapentin, pregabalin, long-acting opioids, peripheral nerve blockade, and patient-controlled analgesia. Numerous studies have revealed not only efficacy but additive and/or synergistic effects when multiple agents are utilized for pain management. Overall, adequate perioperative pain
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40

Kim, Chang-Yeon, Charles Chang, Raysa Cabrejo, and James Yue. Lumbosacral Pain. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190626761.003.0009.

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This chapter examines the options for managing pain after orthopedic spinal surgery in the lumbosacral spine. It reviews the pain syndromes associated with different approaches to the lumbar spine. The chapter explores specific pain syndromes such as failed back syndrome while noting that the majority of pain after spinal surgery results from dissection of soft tissue and muscles. The chapter then discusses oral and parenteral methods for analgesia, as well as spinal and regional nerve blockade. It provides details on the common regimens for pain management including the use of opioids, nonste
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41

Walker, Marc E., David M. Tsai, and J. Grant Thomson. Perioperative Pain Management in Hand and Upper Extremity Surgery. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190457006.003.0020.

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In the past three decades, the number of outpatient surgery centers in the United States has risen exponentially. Hand and upper extremity surgery is no exception, and in many respects, with the modern advancements in anesthesia care, surgery of the hand is one of the best-suited fields for such change. This chapter explores the physiologic aspects of pain, as well as both historical and modern interventions of pain management for such patients. The authors discuss perioperative pharmacological and procedural treatments including various anesthesia options, peripheral and regional nerve blocka
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42

Walters, Jenna L. Complex Regional Pain Syndrome. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190217518.003.0025.

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Complex regional pain syndrome (CRPS) is a neuropathic pain condition classified as type 1 and type 2. The two classifications are distinguished by the presence of documented nerve injury in CRPS type 2. The symptoms of CRPS, including cold, blue, and painful extremities, are believed to occur from vasoconstriction caused by sympathetic dysfunction. Treatment in CRPS focuses on targeting neuropathic and sympathetically maintained pain. Traditional antineuropathic pain medications include membrane stabilizers and serotonin and norepinephrine reuptake inhibitors. Corticosteroids and nonsteroidal
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43

Berrill, Andrew, Will Jones, and David Pegg. Regional anaesthesia of the trunk. Edited by Philip M. Hopkins. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199642045.003.0053.

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Analgesia of the thorax and abdomen can be challenging. Surgical incisions are commonly associated with severe postoperative pain. Whilst continuous epidural analgesia remains the ‘gold standard’ in terms of postoperative pain relief after major surgery, there remain concerns regarding rare serious side effects. It has been difficult to demonstrate conclusive evidence of improvement in outcomes when epidural analgesia is used. Superior pain relief and a reduction in postoperative respiratory morbidity are, however, clear advantages of regional anaesthesia. Interest has increased in techniques
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44

Johnson, Nicholas J., and Judd E. Hollander. Management of cocaine poisoning. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199600830.003.0324.

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Cocaine is powerful central nervous system (CNS) stimulant derived from the coca plant. It affects the body via a number of mechanisms including blockade of fast sodium channels, increased catecholamine release, inhibition of catecholamine reuptake, and increased concentration of excitatory amino acid concentrations in the CNS. It is rapidly absorbed via the aerodigestive, respiratory, gastrointestinal, and genitourinary mucosa, and also may be injected. When injected intravenously or inhaled, cocaine is rapidly distributed throughout the body and CNS, with peak effects in 3–5 minutes. With na
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45

Columb, Malachy O. Local anaesthetic agents. Edited by Michel M. R. F. Struys. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199642045.003.0017.

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Local anaesthetic agents cause a pharmacologically induced reversible neuropathy characterized by axonal conduction blockade. They act by blocking the sodium ionophore and exhibit membrane stabilizing activity by inhibiting initiation and propagation of action potentials. They are weak bases consisting of three components: a lipophilic aromatic ring, a link, and a hydrophilic amine. The chemical link classifies them as esters or amides. Local anaesthetics diffuse through the axolemma as unionized free-base and block the ionophore in the quaternary ammonium ionized form. The speed of onset of b
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