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Journal articles on the topic 'Blockage nerves'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

Mezhenskyi, O. R., and I. B. Philyppov. "Evaluation of the component’s contribution in endothelium-dependent acetylcholine-induced relaxation of the rat aorta." Fiziolohichnyĭ zhurnal 70, no. 2 (2024): 26–34. http://dx.doi.org/10.15407/fz70.02.026.

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The regulation of rat aorta vascular tone involves various factors, including endothelium-derived hyperpolarization factor (EDHF), nitric oxide (NO), prostaglandins, and sensory nerves. While these elements can function independently, their pathways intersect at various points, complicating the assessment of their individual contributions. The aim of this study was to establish the numerical contributions of EDHF, NO, prostaglandins, and also the effect of the sensory nerve on acetylcholine-induced relaxation on the background of phenylephrine preconstriction using contraction and relaxation m

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Shashank, Dhiraj, and Singh Kritika. "Comparing Efficacy of a Single and Triple Injection Techniques in Ultrasound-Guided Costoclavicular Block for Forearm and Hand Surgery: A Single-Blind Randomized Clinical Study." International Journal of Current Pharmaceutical Review and Research 15, no. 01 (2023): 76–82. https://doi.org/10.5281/zenodo.12654550.

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AbstractAim: This study aimed to compare triple injections (TI) in each of the three cords in thecostoclavicular (CC) space would result in a greater spread in the four major terminal nervesof the brachial plexus compared to a single injection (SI) in the CC space without increasingthe local anesthetic (LA) volume.Methods: Fifty patients with ASA physical status 1, 2, and 3 who underwent upper extremitysurgery randomly received either a single injection (SI group, n = 25) or a triple injection (TIgroup, n = 25) using the CC approach. 20 ml of 0.5% ropivacaine was used for BPB in eachgroup. Sen

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Kubota, Yasue, Yoshiyuki Kojima, Yasuhiro Shibata, Makoto Imura, Shoichi Sasaki, and Kenjiro Kohri. "Role of KIT-Positive Interstitial Cells of Cajal in the Urinary Bladder and Possible Therapeutic Target for Overactive Bladder." Advances in Urology 2011 (2011): 1–7. http://dx.doi.org/10.1155/2011/816342.

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In the gastrointestinal tract, interstitial cells of Cajal (ICCs) act as pacemaker cells to generate slow wave activity. Interstitial cells that resemble ICCs in the gastrointestinal tract have been identified by their morphological characteristics in the bladder. KIT is used as an identification marker of ICCs. ICCs in the bladder may be involved in signal transmission between smooth muscle bundles, from efferent nerves to smooth muscles, and from the urothelium to afferent nerves. Recent research has suggested that not only the disturbance of spontaneous contractility caused by altered detru

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Markevich, Denis P., and A. V. Marochkov. "BLOCKADE OF THE PERIPHERAL NERVES IN THE ANESTHETIC MANAGEMENT OF NEUROSURGICAL INTERVENTIONS ON THE HEAD." Regional Anesthesia and Acute Pain Management 11, no. 4 (2017): 270–78. http://dx.doi.org/10.18821/1993-6508-2017-11-4-270-278.

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Objective: to evaluate the effectiveness of peripheral nerve blockades innervating the scalp, in combination with general anesthesia in intra- and postoperative analgesia in patients with neurosurgical interventions. Materials and methods. The efficiency of 105 blockages of the peripheral nerves of the scalp in 18 patients with neurosurgical interventions on the head was evaluated. The age of the patients was 47.5 ± 15.5 years. Patients were operated on for intracranial traumatic and non-traumatic hematomas, brain tumors and the need for plastic of postoperative skull defects. The technique of

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Tuncer, Seçkin, Tülay Tuncer Peker, İlksen Burat, Erhan Kiziltan, Barkin İlhan, and Nizamettin Dalkiliç. "Axonal excitability and conduction alterations caused by levobupivacaine in rat." Acta Pharmaceutica 67, no. 3 (2017): 293–307. http://dx.doi.org/10.1515/acph-2017-0025.

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Abstract In this study, effects of the long-acting amide-type local anesthetic levobupivacaine on axonal conduction and excitability parameters of the rat sciatic nerve were thoroughly examined both in vitro and in vivo. In order to deduce its effects on isolated nerve conduction, compound nerve action potential (CNAP) recordings were performed using the suction method over sciatic nerves of Wistar rats before and after administration of 0.05 % (1.7 mmol L−1) levobupivacaine. Levobupivacaine caused complete CNAP area and amplitude depression by blocking conduction in a time-dependent manner. T

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Haro, P., F. G. Laredo, F. Gil, et al. "Ultrasound-Guided Approach and Blockage of the Sciatic and Femoral Nerves in Felines." Ultrasound in Medicine & Biology 39, no. 5 (2013): S19. http://dx.doi.org/10.1016/j.ultrasmedbio.2013.02.107.

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McRee, Donald I., and Howard Wachtel. "Elimination of Microwave Effects on the Vitality of Nerves after Blockage of Active Transport." Radiation Research 108, no. 3 (1986): 260. http://dx.doi.org/10.2307/3576914.

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Lee, Mi Geum. "Sonographic Guidance for Supraclavicular Brachial Plexus Blocks: Single vs. Double Injection Cluster Approach." september 2017 6, no. 20;6 (2017): 529–35. http://dx.doi.org/10.36076/ppj.20.5.529.

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Background: The cluster approach for supraclavicular brachial plexus block (SC-BPB) can be easily performed but may result in asymmetric local anesthetic (LA) spread. The authors hypothesized that the use of a cluster approach in each of the 2 planes would achieve better 3-dimensional LA distribution than the traditional single cluster approach. Objectives: The purpose of the present study was to compare a double injection (DI) in 2 planes (one injection in each plane) with the traditional single injection (SI) cluster approach for ultrasound-guided SC-BPB. Study Design: A randomized, controll

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Tulgar, Serkan, Ozgur Senturk, Onur Selvi, et al. "Perichondral approach for blockage of thoracoabdominal nerves: Anatomical basis and clinical experience in three cases." Journal of Clinical Anesthesia 54 (May 2019): 8–10. http://dx.doi.org/10.1016/j.jclinane.2018.10.015.

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Dinata, Reyhan, M. Nawawi Noer, and Evelina Ginting. "Soft-Actuator Exoskeleton Glove Berbasis Pneumatik dengan Alat Getaran untuk Terapi Jari Pasien Pasca Stroke." Elektriese: Jurnal Sains dan Teknologi Elektro 15, no. 01 (2025): 1–10. https://doi.org/10.47709/elektriese.v15i01.5677.

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Stroke is a disease caused by a blockage in the blood vessels. This blockage disrupts the circulation of blood and oxygen pumped by the heart to the brain, causing the brain to lack nutrients and affecting brain function, causing parts of the body controlled by the brain, such as the face, hands, and feet, to fail or even become disabled. InI conducted research using the Literature Study and the R&D (Research and Development) methods from this case. The literature study method was chosen for this project because of the need for an in-depth theory that can support the making of this project

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Ganert, A. N., P. A. Lyuboshevskiy, and D. A. Sokolov. "Regional blockage as a component of reduced mammoplasty multimodal pain relief." Patient-Oriented Medicine and Pharmacy 2, no. 4 (2025): 45–52. https://doi.org/10.37489/2949-1924-0067.

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Relevance. Postoperative pain management remains poorly understood. Analgesics traditionally used to treat postoperative pain have numerous side effects. The optimal method for preventing postoperative pain is based on the principle of multimodality, where in addition to the use of analgesics with different application points, regional blockades are applied. In chest wall surgery, blockage of the thoracic nerves (PEC block) and the space of the muscles of the spine straightener (ESP block) under ultrasound control are gaining popularity.Objective. We compared the analgesic efficiency of PEC bl

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Tulgar, Serkan, Ali Ahiskalioglu, Onur Selvi, David Terence Thomas, and Zeliha Ozer. "Similarities between external oblique fascial plane block and blockage of thoracoabdominal nerves through perichondral approach (TAPA)." Journal of Clinical Anesthesia 57 (November 2019): 91–92. http://dx.doi.org/10.1016/j.jclinane.2019.03.027.

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Tamburin, Stefano, Vittorio Schweiger, Francesca Magrinelli, Maria Paola Brugnoli, Giampietro Zanette, and Enrico Polati. "Effect of 5% Lidocaine Medicated Plaster on Pain Intensity and Paroxysms in Classical Trigeminal Neuralgia." Annals of Pharmacotherapy 48, no. 11 (2014): 1521–24. http://dx.doi.org/10.1177/1060028014544166.

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Objective: Trigeminal neuralgia (TN) is a neuropathic pain condition affecting one or more branches of the trigeminal nerve. It is characterized by unilateral, sudden, shock-like, and brief painful attacks, which follow the distribution of trigeminal nerve branches, and with no other accompanying sensorimotor or autonomic signs and symptoms. Current guidelines stipulate which therapies represent first-, second-, and third-line treatments for TN, but there is a consistent mismatch between the therapeutic guidelines and the patient’s preferences and expectations. Case Summary: We report on 2 pat

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Tulgar, Serkan, Onur Selvi, David Terence Thomas, Uğur Deveci, and Zeliha Ozer. "A novel approach to blockage of pectoral nerves: Ultrasound guided Modified Clavipectoral Fascial Plane Block (PECs-Zero)." Journal of Clinical Anesthesia 59 (February 2020): 49–50. http://dx.doi.org/10.1016/j.jclinane.2019.06.024.

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Spees, William M., Tsen-Hsuan Lin, Peng Sun, et al. "MRI-based assessment of function and dysfunction in myelinated axons." Proceedings of the National Academy of Sciences 115, no. 43 (2018): E10225—E10234. http://dx.doi.org/10.1073/pnas.1801788115.

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Repetitive electrical activity produces microstructural alteration in myelinated axons, which may afford the opportunity to noninvasively monitor function of myelinated fibers in peripheral nervous system (PNS)/CNS pathways. Microstructural changes were assessed via two different magnetic-resonance-based approaches: diffusion fMRI and dynamic T2 spectroscopy in the ex vivo perfused bullfrog sciatic nerves. Using this robust, classical model as a platform for testing, we demonstrate that noninvasive diffusion fMRI, based on standard diffusion tensor imaging (DTI), can clearly localize the sites

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Shrutika, Bhagat, Shadab Madiha, and Prasad Sudama. "Comparative Evaluation of Single Injection Vs Triple Injections Utilizing a Costoclavicular Method for Performing Infraclavicular Brachial Plexus Block during Upper Limb Surgery." International Journal of Current Pharmaceutical Review and Research 16, no. 2 (2024): 389–92. https://doi.org/10.5281/zenodo.12740733.

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Aim: To assess the effectiveness of a single injection vs triple injections utilizing a costoclavicular method forperforming infraclavicular brachial plexus block during forearm and hand surgery.Materials and Methods: This study was conducted in the Department of Anesthesia, Patna Medical College andHospital, Patna, Bihar, India for 12 months. Seventy patients scheduled for surgery of the forearm and hand, wereenrolled in the study. Hemodynamic variables (BP, HR, and SPO2) were evaluated. All the patients were kept nilper oral 8 hours prior to surgery. The patients were randomly assigned to ei

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Seong Kin, Foong, Yong Doh Jeing, and Mawaddah Binti Azman. "Nasopharyngeal mucoepidermoid carcinoma: a rare tumor in nasopharynx." International Journal of Otorhinolaryngology and Head and Neck Surgery 5, no. 6 (2019): 1698. http://dx.doi.org/10.18203/issn.2454-5929.ijohns20194953.

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<p class="abstract">Mucoepidermoid carcinoma (MEC) is a malignant epithelial salivary gland neoplasm which consists of a mixture of mucin-producing columnar cells, epidermoid (squamous) cells and polygonal intermediate cells. Salivary gland-type carcinomas are extremely rare to be found in the nasopharynx. A 46-year-old lady presented with bilateral progressive nasal blockage and occasional epistaxis for 3 years. However, there was no neck swelling. Nasoendoscopy revealed a huge nasopharyngeal mass. Tissue biopsy in clinic setting reported of inverted papilloma. Computed tomography shows

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Orfali, Raquel Leao, and Valeria Aoki. "Blockage of the IL-31 Pathway as a Potential Target Therapy for Atopic Dermatitis." Pharmaceutics 15, no. 2 (2023): 577. http://dx.doi.org/10.3390/pharmaceutics15020577.

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Atopic dermatitis (AD), a pruritic, inflammatory chronic disease with multifactorial pathogenesis, has been a therapeutic challenge. Novel target treatments aim to reduce not only the immunologic dysfunction and microbiome dysbiosis but also the recovery of the damaged skin barrier. The current review focuses on the interleukin 31 (IL-31) pathway and AD and offers an overview of the current clinical studies with monoclonal antibodies blocking this cascade. Pruritus, the key symptom of AD, has substantial participation of the IL-31 complex and activation of relevant signaling pathways. Epiderma

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Busch, V., W. Jakob, T. Juergens, W. Schulte-Mattler, H. Kaube, and A. May. "Occipital Nerve Blockade in Chronic Cluster Headache Patients and Functional Connectivity Between Trigeminal and Occipital Nerves." Cephalalgia 27, no. 11 (2007): 1206–14. http://dx.doi.org/10.1111/j.1468-2982.2007.01424.x.

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Headache syndromes often involve occipital and neck symptoms, suggesting a functional connectivity between nociceptive trigeminal and cervical afferents. Although reports regarding effective occipital nerve blockades in cluster headache exist, the reason for the improvement of the clinical symptoms is not known. Using occipital nerve blockade and nociceptive blink reflexes, we were able to demonstrate functional connectivity between trigeminal and occipital nerves in healthy volunteers. The R2 components of the nociceptive blink reflex and the clinical outcome in 15 chronic cluster headache pa

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Broniatowski, Michael, Charles R. Davies, Gordon B. Jacobs, Sharon Grundfest-Broniatowski, Yukihiko Nose, and Harvey M. Tucker. "Electronic Control of Laryngeal Spasm. I. Blockage of Orthodromically Induced Action Potentials in Intact Canine Recurrent Laryngeal Nerves." Laryngoscope 100, no. 8 (1990): 892???895. http://dx.doi.org/10.1288/00005537-199008000-00017.

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21

Chen, Junheng, Chuzhou Ma, and Chunming Guo. "Out-of-plane technique may be the better method for the blockage of thoracoabdominal nerves through perichondrial approach." Journal of Clinical Anesthesia 69 (May 2021): 110155. http://dx.doi.org/10.1016/j.jclinane.2020.110155.

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Kwon, Joonbeom, Duk Yoon Kim, Kang Jun Cho та ін. "Pathophysiology of Overactive Bladder and Pharmacologic Treatments Including β3-Adrenoceptor Agonists -Basic Research Perspectives-". International Neurourology Journal 28, Suppl 1 (2024): 12–33. http://dx.doi.org/10.5213/inj.2448002.001.

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Overactive bladder (OAB) is a symptom-based syndrome defined by urinary urgency, frequency, and nocturia with or without urge incontinence. The causative pathology is diverse; including bladder outlet obstruction (BOO), bladder ischemia, aging, metabolic syndrome, psychological stress, affective disorder, urinary microbiome, localized and systemic inflammatory responses, etc. Several hypotheses have been suggested as mechanisms of OAB generation; among them, neurogenic, myogenic, and urothelial mechanisms are well-known hypotheses. Also, a series of local signals called autonomous myogenic con

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Tulgar, Serkan, Ozgur Senturk, David Terence Thomas, Ugur Deveci, and Zeliha Ozer. "A new technique for sensory blockage of posterior branches of sacral nerves: Ultrasound guided sacral erector spinae plane block." Journal of Clinical Anesthesia 57 (November 2019): 129–30. http://dx.doi.org/10.1016/j.jclinane.2019.04.014.

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Pechersky, V. G. "THE BLOCKADE OF THE SCIATIC NERVE BY SUBGLUTEAL AND POPLITEAL ACCESS PERFORMED UNDER ULTRASOUND GUIDANCE: COMPARISON OF TIME OF THE BLOCK DEVELOPMENT DEPENDING ON THE ACCESS." Health and Ecology Issues, no. 2 (June 28, 2014): 67–70. http://dx.doi.org/10.51523/2708-6011.2014-11-2-14.

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Purpose. The comparison of time needed for development of peripheral blockade of the sciatic nerve, made with 1 % lidocaine and adrenaline (1:200 000) under ultrasound guidance of the subgluteal and popliteal access. Material and methods. Patients were divided into two groups. In group A (20 patients), the blockade of the sciatic nerve was performed by the subgluteal access, in group B (20 patients) - by popliteal access. All the blockades of the sciatic nerve were performed with 30 ml of 1 % lidocaine with adrenaline (1:200 000) with the use of electrical stimulation of the peripheral nerves

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Piacherski, Valery G., and A. V. Marachkou. "The Possibility of blocking the femoral nerve under ultrasound control with the use of the electrical stimulator of the peripheral nerves with small doses of ropivacaine." Regional Anesthesia and Acute Pain Management 12, no. 4 (2018): 217–21. http://dx.doi.org/10.17816/1993-6508-2018-12-4-217-221.

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Goal. The aim of the study is to determine the possibility of using small volumes of ropivacaine for blockade of the femoral nerve performed with the use of an electrostimulator of peripheral nerves under ultrasound. Materials and methods. 44 blockages of the femoral nerve were performed under ultrasound control with the use of electrical stimulation of the peripheral nerves. In the first group (22 patients), a blockade of the femoral nerve was performed with 10 ml of 0.75% ropivacaine; in the second group (22 patients), 0.75% ropivacaine was used in a volume of 5 ml. Evaluation of the d

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Altıparmak, Başak, Melike Korkmaz Toker, Ali İhsan Uysal, Mustafa Turan, and Semra Gümüş Demirbilek. "Reply to Tulgar et al.: Perichondral approach for blockage of thoracoabdominal nerves: Anatomical basis and clinical experience in three cases." Journal of Clinical Anesthesia 54 (May 2019): 150–51. http://dx.doi.org/10.1016/j.jclinane.2018.12.005.

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Balaban, Onur, Serkan Tulgar, Ali Ahiskalioğlu, David Terence Thomas, and Tayfun Aydin. "Blockage of thoracoabdominal nerves through perichondrial approach (TAPA) for surgical anesthesia after failed erector spinae plane block in mini-laparatomy." Journal of Clinical Anesthesia 55 (August 2019): 74–75. http://dx.doi.org/10.1016/j.jclinane.2018.12.054.

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Benzon, Honorio T., Charles Kim, Hazel P. Benzon, et al. "Correlation between Evoked Motor Response of the Sciatic Nerve and Sensory Blockade." Anesthesiology 87, no. 3 (1997): 547–52. http://dx.doi.org/10.1097/00000542-199709000-00014.

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Background Incomplete sensory blockade of the foot after sciatic nerve block in the popliteal fossa may be related to the motor response that was elicited when the block was performed. We investigated the appropriate motor response when a nerve stimulator is used in sciatic nerve block at the popliteal fossa. Methods Six volunteers classified as American Society of Anesthesiologists' physical status I underwent 24 sciatic nerve blocks. Each volunteer had four sciatic nerve blocks. During each block, the needle was placed to evoke one of the following motor responses of the foot: eversion, inve

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de Vries, Liset, and Alfred T. Harding. "Mechanisms of Neuroinvasion and Neuropathogenesis by Pathologic Flaviviruses." Viruses 15, no. 2 (2023): 261. http://dx.doi.org/10.3390/v15020261.

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Flaviviruses are present on every continent and cause significant morbidity and mortality. In many instances, severe cases of infection with flaviviruses involve the invasion of and damage to the central nervous system (CNS). Currently, there are several mechanisms by which it has been hypothesized flaviviruses reach the brain, including the disruption of the blood–brain barrier (BBB) which acts as a first line of defense by blocking the entry of many pathogens into the brain, passing through the BBB without disruption, as well as travelling into the CNS through axonal transport from periphera

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Tanaka, Nobuhiro, Yasunori Yagi, Katsuhiro Aikawa, and Yuji Morimoto. "Anesthetic management by blockage of thoracoabdominal nerves through perichondrial approach (TAPA) for open nephrectomy in a pediatric patient with Wilms tumor." Journal of Clinical Anesthesia 59 (February 2020): 51–52. http://dx.doi.org/10.1016/j.jclinane.2019.06.019.

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VINCENT, MAURICE B., RENATO A. LUNA, DENISE SCANDIUZZI, and SÉRGIO A. P. NOVIS. "Greater occipital nerve blockade in cervicogenic headache." Arquivos de Neuro-Psiquiatria 56, no. 4 (1998): 720–25. http://dx.doi.org/10.1590/s0004-282x1998000500004.

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Cervicocogenic headache (CeH) is a relatively common disorder. Although no ideal treatment is available so far, blockades in different structures and nerves may be temporarily effective. We studied the effects of 1-2 mL 0.5% bupivacaine injection at the ipsilateral greater occipital nerve (GON) in 41 CeH patients. The pain is significantly reduced both immediately and as long as 7 days after the blockade. The improvement is less marked during the first two days, a phenomenon we called "tilde pattern". GON blockades may reduce the pool of exaggerated sensory input and antagonize a putative "win

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Tokat, O., YG Türker, N. Uckunkaya, and A. Yilmazlar. "A Clinical Comparison of Psoas Compartment and Inguinal Paravascular Blocks Combined with Sciatic Nerve Block." Journal of International Medical Research 30, no. 2 (2002): 161–67. http://dx.doi.org/10.1177/147323000203000208.

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The extent of inguinal paravascular blockade and psoas compartment blockade with sciatic nerve block was evaluated in 60 patients. Volumes of 30 ml and 20 ml 0.35% bupivacaine with 1/200 000 epinephrine were injected for lumbar plexus and sciatic nerve block, respectively. Complete lumbar plexus blockade was achieved in 73% of the group who were treated with the psoas compartment technique and 43% of the group who were treated with the inguinal paravascular technique. Sensory blockade of the femoral, lateral femoral cutaneous and obturator nerves was obtained in 100%, 97% and 77% of the patien

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Umar, Abubakar M., and Abubakar Aisami. "Acetylcholinesterase Enzyme (AChE) as a Biosensor and Biomarker for Pesticides: A Mini Review." Bulletin of Environmental Science and Sustainable Management (e-ISSN 2716-5353) 4, no. 1 (2020): 7–12. http://dx.doi.org/10.54987/bessm.v4i1.526.

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Due to the increase in pesticide usage the cost of food production has been drastically reduced worldwide. There are dangers related to the ever-increasing pesticide application especially to the non-target biota and to also to the environment at large. Pesticides bind with the active site of acetylcholinesterase (AChE) and inhibit the breakdown of acetylcholine and causes the blockage of synaptic transmission in cholinergic nerves. When AChE is inhibited, ChE accumulates and the nerve impulse cannot be stopped, leading to muscle contraction, paralysis and sometimes dead may occur. Pesticides

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KUSHTA, ANNA O., and SERGII M. SHUVALOV. "FEATURES OF THE TOPOGRAPHIC-ANATOMIC STRUCTURE OF THE PERHOLOUS-LOWER MANDAL SPACE AFFECTING THE EFFICIENCY OF NERVEBLOCKADES AND OTHER SURGICAL INTERVENTIONS." Bulletin of Contemporary Clinical Medicine 15, no. 2 (2022): 117–23. http://dx.doi.org/10.20969/vskm.2022.15(2).117-123.

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Introduction. The region of the pterygo-mandibular space is an anatomical formation that is quite often sub- jected to surgical interventions (blockade of the mandibular nerve and its branches, operations for purulent processes, injuries). Among the complications of these surgical interventions, there are contractures of the lower jaw, neuritis of the lower alveolar and lingual nerves, and failure of anesthesia during blockades of these nerves. The purpose of the study was to analyze literature data and anatomical preparations of the pterygo-mandibular space, to take into account different opt

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Jain, Rajat. "POST-COVID ROCM (RHINO ORBITAL CEREBRAL MUCORMYCOSIS) INVOLVING SKULL BASE – A RARE CASE REPORT." UP STATE JOURNAL OF OTOLARYNGOLOGY AND HEAD AND NECK SURGERY 11, no. 1 (2023): 44–48. http://dx.doi.org/10.36611/upjohns/volume11/issue1/7.

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INTRODUCTION Mucormycosis in the setting of COVID-19 has given rise to the concept of 'epidemic within a pandemic'. It is a life-threatening fungal infection caused by fungi belonging to class Zygomycetes. It has got special affinity for the immunocompromised which is one of the main reasons for the flare up of the disease during COVID. Rhino-orbito-cerebral Mucormycosis (ROCM) is by far known to be the most common form of this disease. This usually presents with nasal dryness and blockage, swelling and numbness of cheek, blackish discoloration of nose, cheek and palate. It has been seen that

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Gupta, Priyanshi, Digvijay Singh Rawat, Yogesh Aseri, PC Verma, and BK Singh. "Allergic Fungal Sinusitis with Bilateral Optic Neuropathy." Bengal Journal of Otolaryngology and Head Neck Surgery 29, no. 3 (2022): 314–18. http://dx.doi.org/10.47210/bjohns.2021.v29i3.537.

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Introduction Allergic Fungal Rhinosinusitis (AFRS) is characterized by an inflammatory response to a non-invasive fungus which leads to sinus obstruction. Ophthalmic manifestations of AFRS are rare but can be of grave consequence. Case Report A 22-year-old female patient presented with a 5-day history of headache and decreased vision in both eyes (right- perception of light; left-6/18), along with a past history of nasal blockage and recurrent rhinorrhoea. She had thick viscid mucous secretion with polyposis in bilateral nasal cavities. Computed tomography showed pansinusitis with heterogenous

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Chang, Yung-Ming, Wu-Hsien Kuo, Tung-Yuan Lai, et al. "RSC96 Schwann Cell Proliferation and Survival Induced by Dilong through PI3K/Akt Signaling Mediated by IGF-I." Evidence-Based Complementary and Alternative Medicine 2011 (2011): 1–9. http://dx.doi.org/10.1093/ecam/nep216.

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Schwann cell proliferation is critical for the regeneration of injured nerves. Dilongs are widely used in Chinese herbal medicine to remove stasis and stimulate wound-healing functions. Exactly how this Chinese herbal medicine promotes tissue survival remains unclear. The aim of the present study was to investigate the molecular mechanisms by which Dilong promote neuron regeneration. Our results show that treatment with extract of Dilong induces the phosphorylation of the insulin-like growth factor-I (IGF-I)-mediated phosphatidylinositol 3-kinase/serine-threonine kinase (PI3K/Akt) pathway, and

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Price, D. J. "The Shoulder Block: A New Alternative to Interscalene Brachial Plexus Blockade for the Control of Postoperative Shoulder Pain." Anaesthesia and Intensive Care 35, no. 4 (2007): 575–81. http://dx.doi.org/10.1177/0310057x0703500418.

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This report describes the development of the shoulder block, an alternative to interscalene brachial plexus blockade for the control of postoperative pain following shoulder surgery. Included is a review of the relevant anatomy of the shoulder joint and its associated structures. Two nerves provide the bulk of the innervation to this area: the suprascapular nerve and the axillary (circumflex) nerve. The shoulder block technique involves selective blockade of both of these nerves instead of general blockade of the entire brachial plexus via the interscalene route. The technique of Meier is used

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Chang, Yung-Ming, Wei-Yi Chi, Tung-Yuan Lai, et al. "Dilong: Role in Peripheral Nerve Regeneration." Evidence-Based Complementary and Alternative Medicine 2011 (2011): 1–9. http://dx.doi.org/10.1093/ecam/neq079.

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Dilong, also known as earthworm, has been widely used in traditional Chinese medicine (TCM) for thousands of years. Schwann cell migration and proliferation are critical for the regeneration of injured nerves and Schwann cells provide an essentially supportive role for neuron regeneration. However, the molecular mechanisms of migration and proliferation induced by dilongs in Schwann cells remain unclear. Here, we discuss the molecular mechanisms that includes (i) migration signaling, MAPKs (mitogen-activated protein kinases), mediated PAs and MMP2/9 pathway; (ii) survival and proliferative sig

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Trivedi, Saurabh, Srishti Gupta, Hemendra Bhardwaj, Tapan Kumar Sahoo, Seema Gupta, and Gaurav Trivedi. "Efficacy of intertruncal and corner-pocket approaches of ultrasound-guided supraclavicular block in terms of ulnar nerve blockade: A randomised controlled study." Indian Journal of Anaesthesia 67, no. 9 (2023): 778–84. http://dx.doi.org/10.4103/ija.ija_45_23.

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ABSTRACT Background and Aims: The incidence of ulnar nerve sparing has declined with the corner-pocket approach of the supraclavicular block (SCB), however, it continues to persist. A recent technique of SCB, the intertruncal approach, separately blocks each trunk of the brachial plexus. Thus, we hypothesised that the intertruncal approach results in a complete ulnar nerve blockade. Methods: Eighty-eight patients were randomised to undergo SCB using an ultrasound (USG)-guided corner-pocket or intertruncal approach and were compared primarily regarding the complete sensory and motor blockade of

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Gad, Monika, Anders Elm Pedersen, Nanna Ny Kristensen, Carmen de Felipe Fernandez, and Mogens H. Claesson. "Blockage of the neurokinin 1 receptor and capsaicin-induced ablation of the enteric afferent nerves protect SCID mice against T-cell-induced chronic colitis." Inflammatory Bowel Diseases 15, no. 8 (2009): 1174–82. http://dx.doi.org/10.1002/ibd.20902.

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Seidler, Nicholas, Olivia Terlep, and Vendhan Ramanujam. "Peripheral nerve blocks for through-knee amputation in a patient on extracorporeal membrane oxygenation." BMJ Case Reports 17, no. 3 (2024): e259987. http://dx.doi.org/10.1136/bcr-2024-259987.

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A woman in her 40s with an ischaemic right lower limb, who was on extracorporeal membrane oxygenation (ECMO) following cardiopulmonary failure secondary to bilateral alveolar haemorrhage, was scheduled for through-knee amputation. She was under mechanical ventilation and continuous intravenous medications. Considering her significant comorbidities, peripheral nerve blocks were chosen for anaesthesia. Ultrasound-guided traditional nerve blockade techniques of the femoral and sciatic nerves were not possible because of the presence of an ECMO cannula, altered anatomy following previous surgery o

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Tang, Rui, Ron Perez, David M. Brogan, Mikhail Y. Berezin, and James E. McCarthy. "Imaging Peripheral Nerves In Vivo with CT Neurogram Using Novel 2,4,6-Tri-Iodinated Lidocaine Contrast Agent." Bioengineering 12, no. 4 (2025): 422. https://doi.org/10.3390/bioengineering12040422.

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Peripheral nerve injuries are a significant concern in surgical procedures, often leading to chronic pain and functional impairment. Despite advancements in imaging, preoperative and intraoperative visualization of peripheral nerves remains a challenge. This study introduces and evaluates a novel tri-iodinated lidocaine-based contrast agent for computed tomography neurography, aiming to enhance the intraoperative visibility of peripheral nerves in vivo. A tri-iodinated lidocaine analogue was synthesized and characterized for its radiodensity, sodium channel binding and nerve affinity. Sodium c

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Brummett, Chad M., Mary A. Norat, John M. Palmisano, and Ralph Lydic. "Perineural Administration of Dexmedetomidine in Combination with Bupivacaine Enhances Sensory and Motor Blockade in Sciatic Nerve Block without Inducing Neurotoxicity in Rat." Anesthesiology 109, no. 3 (2008): 502–11. http://dx.doi.org/10.1097/aln.0b013e318182c26b.

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Background The current study was designed to test the hypothesis that high-dose dexmedetomidine added to local anesthetic would increase the duration of sensory and motor blockade in a rat model of sciatic nerve blockade without causing nerve damage. Methods Thirty-one adult Sprague-Dawley rats received bilateral sciatic nerve blocks with either 0.2 ml bupivacaine, 0.5%, and 0.5% bupivacaine plus 0.005% dexmedetomidine in the contralateral extremity, or 0.2 ml dexmedetomidine, 0.005%, and normal saline in the contralateral extremity. Sensory and motor function were assessed by a blinded invest

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Boro, Fabian Dominggus Eka, and Endang Sugiharti. "Combination of Genetic Algorithm and Spiking Neural Network Leaky Integrate-And-Fire Model in Analyzing Brain Ct Scan Image for Stroke Disease Detection." Recursive Journal of Informatics 3, no. 1 (2025): 1–14. https://doi.org/10.15294/rji.v3i1.3492.

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Abstract. Stroke is a condition where there is impaired brain function due to lack of oxygen caused by blockage, breakdown, or blood clots inside brain. Diagnosis of stroke is usually based on symptoms, but symptoms are not always the correct measure. In examining a stroke, the most common way to examine a patient is to perform a CT scan of the brain. Purpose: This study was conducted with the aim of predicting brain scan images consisting of normal brain, ischemic stroke brain, and hemorrhagic stroke brain. It is also to understand how an algorithm works to recognize and predict an image. Met

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Noh, Mi, Hee-Seong Jang, Jinu Kim, and Babu Padanilam. "Renal Sympathetic Nerve-Derived Signaling in Acute and Chronic Kidney Diseases." International Journal of Molecular Sciences 21, no. 5 (2020): 1647. http://dx.doi.org/10.3390/ijms21051647.

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The kidney is innervated by afferent sensory and efferent sympathetic nerve fibers. Norepinephrine (NE) is the primary neurotransmitter for post-ganglionic sympathetic adrenergic nerves, and its signaling, regulated through adrenergic receptors (AR), modulates renal function and pathophysiology under disease conditions. Renal sympathetic overactivity and increased NE level are commonly seen in chronic kidney disease (CKD) and are critical factors in the progression of renal disease. Blockade of sympathetic nerve-derived signaling by renal denervation or AR blockade in clinical and experimental

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Koriachkin, V. A., D. V. Zabolotskii, D. V. Gribanov, and T. A. Antoshkova. "Obturator nerve block." Regional Anesthesia and Acute Pain Management 14, no. 3 (2021): 130–40. http://dx.doi.org/10.17816/1993-6508-2020-14-3-130-140.

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One of the forgotten techniques of regional anesthesia is blockade of the obturator nerve, which was performed using anatomical landmarks and neurostimulation. In recent years, ultrasonic navigation methods have gained wide popularity when using regional blockades. The purpose of the review is to present the current understanding of the use of obturator nerve block in clinical practice. The review presents the anatomical features of the obturator nerve passage, surgical and therapeutic indications for the use of its blockade. The technique for performing obturator blockade using ultrasound nav

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Evangelista, Marina C., Beatriz P. Monteiro, Graeme M. Doodnaught, Pascale Benoist, and Paulo V. Steagall. "Paravertebral brachial plexus blockade in cats: a cadaver study." Journal of Feline Medicine and Surgery 20, no. 6 (2017): 591–95. http://dx.doi.org/10.1177/1098612x17718437.

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Objectives The aims of this study were to describe the paravertebral brachial plexus (PBP) blockade in cats, and compare the spread of bupivacaine–methylene blue solution (BMS) using two volumes of injection into the PBP. Methods Six cadavers (4.4 ± 1.8 kg) randomly received 0.15 ml/kg (LOW) or 0.2 ml/kg (HIGH) per injection of BMS into the PBP. The first injection was made ventral to the transverse process of the sixth cervical vertebra (nerves C6 and C7) at the emergence of nerve roots. A second injection was performed at the edge of the cranial border of the scapula and directed ventrally t

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Steers, W. D., B. Mallory, and W. C. de Groat. "Electrophysiological study of neural activity in penile nerve of the rat." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 254, no. 6 (1988): R989—R1000. http://dx.doi.org/10.1152/ajpregu.1988.254.6.r989.

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Electrophysiological techniques were used to examine the axonal composition and reflex activity of the penile nerve of the rat. Stimulation of either the pelvic nerve, hypogastric nerve, or sympathetic chain elicited synaptic and axonal volleys in the penile nerve. Synaptic responses were suppressed by nicotinic ganglionic blockade, indicating that they were mediated by cholinergic transmission in peripheral ganglia. Axonal volleys represented in part afferent pathways from receptors in the pelvic muscles, perineum, and anus. Stimulation of the penile or pelvic nerves increased intracavernous

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Fonkoue, Loïc, Catherine Wydemans Behets, Arnaud Steyaert, et al. "Accuracy of fluoroscopic-guided genicular nerve blockade: a need for revisiting anatomical landmarks." Regional Anesthesia & Pain Medicine 44, no. 10 (2019): 950–58. http://dx.doi.org/10.1136/rapm-2019-100451.

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Background and objectivesGenicular nerve blockade (GNB) and radiofrequency ablation (RFA) have recently emerged as treatment options for patients with chronic knee pain. However, an increasing number of anatomical studies and systematic reviews concluded that the anatomical basis for needle placement was unclear, incomplete and somewhat inaccurate. This study was designed to assess the accuracy of updated anatomical landmarks for fluoroscopy-guided blockade of the consistent genicular nerves in a cadaveric model.MethodsBased on a comprehensive review of recent anatomical studies and prior diss

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