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Dissertations / Theses on the topic 'Carcinoma, squamous cell: diagnosis'

Author: Grafiati

Published: 4 June 2021

Last updated: 7 February 2022

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1

Qadir, Fatima. "Cellular and molecular signature of oral squamous cell carcinoma." Thesis, Queen Mary, University of London, 2018. http://qmro.qmul.ac.uk/xmlui/handle/123456789/39763.

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Oral squamous cell carcinoma (OSCC) is the sixth most common cancer worldwide. It is a result of numerous aetiological factors such as genetic predisposition, smoking, excessive alcohol consumption and viruses such as the human papilloma virus. Due to late diagnosis it has a high mortality and morbidity rates which has remained unchanged over the last 5 decades. Currently no screening is available for high risk patients for better monitoring. Diagnosing OSCC relies on histopathology of biopsy tissue, reviewed for dysplasia and advancing lesions. Although the technique has been used for decades

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2

Högmo, Anders. "Squamous cell carcinomas and preneoplastic lesions of the oral cavity : biological factors and prognosis /." Stockholm, 1999. http://diss.kib.ki.se/1999/91-628-3370-7/.

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3

Ekberg, Tomas. "Diagnosis and Radioimmunotherapy of Head and Neck Squamous Cell Carcinomas." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis : Universitetsbiblioteket [distributör], 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-8395.

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4

Macleod, R. I. "Applications of cytology to the diagnosis and prognosis of oral squamous cell carcinoma." Thesis, University of Newcastle Upon Tyne, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.329277.

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5

Chan, Pui-man Poemen, and 陳培文. "Micrometastases of esophageal cancer." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2006. http://hub.hku.hk/bib/B45012842.

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6

LE, HOANG BA PATRICK. "Interet diagnostic du squamous cell carcinoma en pathologie pleuropulmonaire." Nice, 1988. http://www.theses.fr/1988NICE6550.

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7

Kwong, Rhonda A. St Vincent's Clinical School UNSW. "Molecular markers of prognosis & therapeutic response in head & neck squamous cell carcinoma." Awarded by:University of New South Wales. St Vincent's Clinical School, 2005. http://handle.unsw.edu.au/1959.4/22460.

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Head and neck cancers account for 3% of all newly diagnosed cancers, of which 90% are squamous cell carcinomas (SCC). Improvements in surgery, radiotherapy and chemotherapy have done little to improve the mortality of this disease over the past 20 years while current clinicopathological predictors of disease outcome are sub-optimal. Identifying molecular targets of prognostic and therapeutic significance in head and neck squamous cell carcinomas (HNSCC) may help direct novel therapies to patients whom it is most likely to benefit. Accrued knowledge of the biology of HNSCC has highlighted speci

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8

Haylock, Anna-Karin. "Targeting molecules for diagnostics of Head and Neck squamous cell carcinoma." Doctoral thesis, Uppsala universitet, Öron-, näs- och halssjukdomar, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-315210.

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To personalize treatment for cancer, correct staging of the primary tumor, nodal disease and metastatic disease is of essence. By targeting tumor specific receptors with radiolabeled antibodies, specificity and accuracy of imaging may be improved. Radio-immunodiagnostics can potentially detect small volume disease, occult metastasis and recurrent cancer in treated tissue. This thesis focuses on evaluation of radio-immunoconjugates directed towards CD44v6, which is a surface receptor overexpressed in many head and neck squamous cell carcinomas. At the outset, the monoclonal chimeric antibody cM

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9

Zheng, Xiangpeng. "Specificity and feasibility of HN-5 peptide for diagnosis and targeted therapy of head and neck squamous cell carcinomas : a dissertation /." San Antonio : UTHSC, 2007. http://proquest.umi.com/pqdweb?did=1400957411&sid=1&Fmt=2&clientId=70986&RQT=309&VName=PQD.

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10

Daher, Tamás [Verfasser]. "Comparative TP53 targeted next generation sequencing analysis as a diagnostic tool for determining lung tumor origin in patients with head and neck squamous cell carcinoma and synchronous / metachronous squamous cell lung carcinoma / Tamás Daher." Gießen : Universitätsbibliothek, 2018. http://d-nb.info/1170582079/34.

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11

Prado, Flavio Augusto Passarelli. "Avaliação por endoscopia de contato do papiloma invertido schneideriano e do carcinoma espinocelular nasossinusal." Universidade de São Paulo, 2010. http://www.teses.usp.br/teses/disponiveis/5/5143/tde-13092010-145428/.

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Introdução: A endoscopia de contato (EC) foi um exame descrito inicialmente como método de analise da histologia uterina e das cordas vocais. Os primeiros estudos utilizando a EC nas cavidades nasais mostraram resultados promissores na diferenciação de lesões benignas, considerando que a biópsia tradicional pode trazer algumas complicações. Objetivo: Descrever e comparar os achados da EC no papiloma schneideriano invertido e no carcinoma espinocelular nasossinusal e testar a efetividade do exame como método não invasivo in vivo para diferenciação entre esses tumores. Métodos: Os pacientes incl

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12

Lima, Cássio Aparecido. "Caracterização bioquímica de lesões neoplásicas via espectroscopia de absorção no infravermelho por transformada de Fourier." Universidade de São Paulo, 2015. http://www.teses.usp.br/teses/disponiveis/85/85134/tde-28082015-100900/.

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Cânceres de pele não melanoma (CPNM) representam 95% das neoplasias cutâneas, dentre as quais o carcinoma espinocelular (CEC) é a forma mais agressiva devido a seu padrão de crescimento invasivo e possivelmente metastático. O padrão ouro para o diagnóstico é o exame clínico e avaliação histopatológica, que são subjetivos e dependem da experiência do médico e patologista envolvidos no procedimento. Considerando que o diagnóstico precoce é fundamental para alcançar um tratamento com resultados favoráveis, o presente trabalho utilizou a espectroscopia FTIR (Fourier transform infrared spectroscopy

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13

Burzlaff, João Batista. "Estudos sobre a aplicabilidade da citopatologia no diagnóstico precoce do câncer bucal." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2007. http://hdl.handle.net/10183/11121.

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O câncer bucal é uma doença que afeta principalmente homens acima de 40 anos com hábito de fumar e beber. Em geral, esses pacientes têm o diagnóstico da enfermidade realizado tardiamente, acarretando tratamentos complexos, mutilantes e de alto custo tanto financeiro como social e de prognóstico sombrio a ponto do câncer bucal apresentar uma taxa de sobrevida em 5 anos inferior a 50%. O diagnóstico precoce representa uma alternativa importante para alterar esse panorama. Os recursos de que os profissionais da área da saúde, principalmente os cirurgiões-dentistas, dispõem são o diagnóstico clíni

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14

Rollakanti, Kishore Reddy. "Protoporphyrin IX Fluorescence for Enhanced Photodynamic Diagnosis and Photodynamic Therapy in Murine Models of Skin and Breast Cancer." Cleveland State University / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=csu1431466604.

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15

Mizobe-Ono, Lia 1969. "Estudo epidemiológico retrospectivo das lesões bucais diagnosticadas na Fundação Centro e Controle de Oncologia do Estado do Amazonas (FCECON) entre os anos de 1998 a 2009." [s.n.], 2011. http://repositorio.unicamp.br/jspui/handle/REPOSIP/287876.

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Orientador: Marcio de Moraes<br>Tese (doutorado) - Universidade Estadual de Campinas, Faculdade de Odontologia de Piracicaba<br>Made available in DSpace on 2018-08-18T19:58:24Z (GMT). No. of bitstreams: 1 Mizobe-Ono_Lia_D.pdf: 1581690 bytes, checksum: 4c127d8ad800ec334ace4dd29173cca1 (MD5) Previous issue date: 2011<br>Resumo: A falta de estudos epidemiológicos a respeito de determinadas doenças, pode afetar o desenvolvimento de determinados programas de prevenção. Na região Norte do Brasil dados epidemiológicos sobre as lesões da cavidade bucal são escassos. Em muitos casos os tumores malign

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16

Francisco, Ana Lucia Noronha. "System of fluorescence spectroscopy in the evaluation of surgical margins for squamous cell carcinoma of the oral cavity in moments in situ and ex vivo = Sistema de espectroscopia de fluorescência na avaliação de margens cirúrgicas de carcinoma de células escamonas da cavidade oral nos momentos in situ e ex vivo." [s.n.], 2013. http://repositorio.unicamp.br/jspui/handle/REPOSIP/289799.

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Orientadores: Luiz Paulo Kowalski, Cristina Kurachi<br>Tese (doutorado) - Universidade Estadual de Campinas, Faculdade de Odontologia de Piracicaba<br>Made available in DSpace on 2018-08-23T09:12:17Z (GMT). No. of bitstreams: 1 Francisco_AnaLuciaNoronha_D.pdf: 1746316 bytes, checksum: 57e6c356302ad93eddf308f33c31ff65 (MD5) Previous issue date: 2013<br>Resumo: O tratamento mais empregado para os carcinomas de células escamosas da boca é a ressecção cirúrgica, sendo ou não acompanhada de radio e/ou quimioterapia. O tratamento é simplificado, diminuindo número de recidivas e aumentando a sobrev

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17

Marinho, Erasmo Bernardo. "Evaluation of the quality of life of post- irradiated patients diagnosed with squamous cell carcinoma of the oral cavity." Universidade Federal do CearÃ, 2016. http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=16162.

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Radiotherapy is an effective therapeutic modality employed in the management of malignant tumors in the oral cavity. Its use in head and neck results in adverse effects. The measurement of quality of life allows to gather the most common problems in oral cancer patients in a structured way, ranking its intensity and enabling a more accurate clinical control. This study aimed to evaluate the quality of life of post- irradiated diagnosed with squamous cell carcinoma of the oral cavity. Eleven patients over six months of completion of therapy treated at the Hospital Haroldo JuaÃaba â Instituto do

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18

Liu, Muyuan, Steven J. Wang, Xihong Yang, and Hanwei Peng. "Diagnostic Efficacy of Sentinel Lymph Node Biopsy in Early Oral Squamous Cell Carcinoma: A Meta-Analysis of 66 Studies." PUBLIC LIBRARY SCIENCE, 2017. http://hdl.handle.net/10150/622744.

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Objectives The diagnostic efficacy of sentinel lymph node biopsy(SLNB) in early oral squamous cell carcinoma(OSCC) still remains controversial. This meta-analysis was conducted to assess the diagnostic value of SLNB in clinically neck-negative T1-2 OSCC. Methods A systematic literature search for relevant literature published up to September 11, 2016 was conducted in PubMed, Embase, Web of Science, Cochrane Library and ClinicalTrials, and the reference lists of eligible studies were examined. Data from different studies were pooled to estimate the summary sentinel lymph node(SLN) identificatio

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19

Timmerman, Alexandra. "Neck ultrasound as a diagnostic method of cervical lymph node metastasis in patients with Head and Neck squamous cell carcinoma." Thesis, Örebro universitet, Institutionen för medicinska vetenskaper, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-55111.

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20

Ide, Edson. "Cromoscopia óptica com tecnologia de banda estreita versus cromoscopia com solução de Lugol no diagnóstico do carcinoma superficial de esôfago em pacientes com câncer de cabeça e pescoço." Universidade de São Paulo, 2010. http://www.teses.usp.br/teses/disponiveis/5/5154/tde-03092010-103902/.

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Presente estudo teve como objetivo avaliar a utilização da tecnologia de banda estreita com filtros ópticos (TBE) no rastreamento do carcinoma espinocelular do esôfago (CEC), utilizando como método comparativo a cromoscopia com a solução de Lugol. Trata-se de um estudo prospectivo de teste de diagnóstico, para o qual foram avaliados 129 pacientes do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (HC-FMUSP), com diagnóstico de carcinoma epidermóide de cabeça e pescoço, em programa de rastreamento de tumores secundários, no período de agosto de 2006 a fevereiro de 20

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21

Hanns, Elodie. "Analyse et caractérisation moléculaire de l'hypoxie intratumorale de carcinomes épidermoïdes de l'oropharynx." Thesis, Strasbourg, 2014. http://www.theses.fr/2014STRAJ063/document.

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Les carcinomes épidermoïdes des voies aéro-digestives supérieures (VADS) se situent au sixième rang des cancers les plus fréquents dans le monde. Ces tumeurs sont liés à deux facteurs de risque : l’intoxication éthylo-tabagique (80% des cas) et l’infection de l’épithélium des VADS par les papillomavirus humain (HPV) à haut risque oncogène (20% des cas). Ces derniers définissent une sous-population de patients de meilleur pronostic. Une des hypothèses actuellement étudiées, afin d’expliquer la survie améliorée des patients HPV positifs, serait une hypoxie moindre dans ces tumeurs. En effet, les

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22

Mota, Orlando Milhomem da. "Câncer do esôfago: repercussões metabólico-nutricionais da reconstrução do trânsito após esofagectomia; análise comparativa de gastroplastia versus coloplastia." Universidade de São Paulo, 2003. http://www.teses.usp.br/teses/disponiveis/5/5154/tde-22092014-111201/.

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Foram analisados retrospectivamente os prontuários de 97 pacientes portadores de carcinoma do esôfago quanto às complicações intra-operatórias, complicações pós-operatórias precoces, complicações pós-operatórias tardias, alterações digestivas e nutricionais, mortalidade pós-operatória, qualidade de vida e sobrevida até 24 meses, após a reconstrução do trânsito esofágico, comparando esofagocoloplastia versus esofagogastroplastia. Os pacientes foram divididos em dois grupos: A, reconstruídos com o colon (55 pacientes) e B, reconstruídos com o tubo gástrico (42 pacientes). A histologia foi carcin

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23

Furuse, Cristiane [UNESP]. "Espectroscopia FT-Raman no diagnóstico do carcinoma espinocelular de mucosa bucal: estudo ex vivo em humanos." Universidade Estadual Paulista (UNESP), 2006. http://hdl.handle.net/11449/102335.

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Made available in DSpace on 2014-06-11T19:32:06Z (GMT). No. of bitstreams: 0 Previous issue date: 2006-12-18Bitstream added on 2014-06-13T20:03:00Z : No. of bitstreams: 1 furuse_cf_dr_araca.pdf: 882219 bytes, checksum: 8a99459009b7acb3dd5a0a1aaea84d8f (MD5)<br>Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)<br>O câncer é uma das doenças mais sérias que têm ameaçado a saúde e a vida e sua influência tem aumentado. Dentre os cânceres, o de boca constitui-se um grave problema de saúde pública em várias regiões do mundo, inclusive em países desenvolvidos, estando entre os 10

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24

Priante, Antonio Vitor Martins. "A importância da tríplice endoscopia no diagnóstico de neoplasias primárias múltiplas em pacientes com carcinoma epidermóide de vias aerodigestivas superiores." Universidade de São Paulo, 2010. http://www.teses.usp.br/teses/disponiveis/5/5155/tde-20042010-095730/.

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INTRODUÇÃO: Pacientes com carcinomas das vias aerodigestivas superiores (VADS) apresentam um alto risco de desenvolver outros cânceres tanto simultaneamente quanto subsequentemente. A maioria destes tumores ocorre nas VADS, pulmões ou esôfago. A tríplice endoscopia (laringoscopia, endoscopia digestiva alta e broncoscopia) possibilita o diagnostico de lesões precursoras e de tumores invasivos. No entanto, a maioria dos estudos limita-se a descrever a frequência de diagnósticos, mas não os resultados do tratamento e o impacto na sobrevida. OBJETIVOS: Avaliar a importância da tríplice endoscopia

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25

Pennacchi, Caterina Maria Pia Simioni. "Detecção da neoplasia do esôfago em pacientes com estenose por ingestão de agente corrosivo: estudo comparativo entre o emprego da técnica de cromoscopia óptica e o uso de cromoscopia de contraste." Universidade de São Paulo, 2009. http://www.teses.usp.br/teses/disponiveis/5/5154/tde-22022010-172835/.

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Introdução: Narrow-Band Imaging (NBI) é uma das mais recentes técnicas de processamento de imagem, que consiste na utilização de filtros para dissociação das bandas do espectro da luz, resultando em aumento de contraste da superfície epitelial e da vascularização. Em combinação com a magnificação de imagem, pode-se diferenciar os tipos epiteliais e identificar áreas de padrão vascular decorrente de processos inflamatórios ou de neoplasias superficiais. A utilização da endoscopia associada à cromoscopia com solução de Lugol já é método consagrado na detecção de lesões superficiais em pacientes

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26

Nkomo, Nocwaka. "The description of diagnosed cases of Oral Epithelial Dysplasia at the Tygerberg Oral Health Centre." University of the Western Cape, 2020. http://hdl.handle.net/11394/8053.

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Magister Scientiae Dentium - MSc(Dent)<br>Oral epithelial dysplasia (OED) is a growth anomaly which occurs as a result of atypical, abnormal proliferation and a change in the architecture and cytological features of cells of epithelial origin, which ultimately results in the formation of a lesion with disturbed differentiation and maturation The purpose of this study was to describe the OED cases diagnosed at Tygerberg Oral health centre in a 7-year period between 2012 and 2019. The patients’ medical records from Tygerberg Oral Health Centre and National Health Laboratory Service (NHLS) were r

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27

Schlürmann, Kai Nikolas [Verfasser]. "Einfluss und Vorhersagewahrscheinlichkeit der präoperativen radiologischen Diagnostik beim Plattenepithelkarzinom der Mundhöhle auf die folgenden Therapieentscheidungen : Influence and prediction probability of preoperative radiological diagnostics in oral squamous cell carcinoma on the following therapeutic decisions / Kai Nikolas Schlürmann." Hamburg : Staats- und Universitätsbibliothek Hamburg Carl von Ossietzky, 2020. http://d-nb.info/1221084054/34.

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28

Ebrahimi, Majid. "Studies of p63 and p63 related proteins in patients diagnosed with oral lichen planus." Doctoral thesis, Umeå : Univ, 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1437.

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29

Nestor, Marika. "Antibody-Based Radionuclide Targeting for Diagnostics and Therapy : Preclinical Studies on Head and Neck Cancer." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis, 2006. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-7341.

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30

Abgral, Ronan. "Tomographie par émission de positons au 18F-fluorodesoxyglucose et carcinome épidermoïde des voies aérodigestives supérieures réfractaire au traitement." Phd thesis, Université de Bretagne occidentale - Brest, 2013. http://tel.archives-ouvertes.fr/tel-00952418.

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Nous avons initialement réalisé une étude prospective évaluant l'intérêt de la TEP-TDM au FDG pour le diagnostic de récidive infra-clinique des carcinomes épidermoïdes des voies aéro-digestives supérieures. Nos résultats ont montré d'excellentes performances de l'examen en surveillance systématique, permettant notamment le diagnostic de récidive chez environ 1/3 des patients cliniquement asymptomatiques 1 an après la fin du traitement. Nous avons ensuite étudié le bénéfice d'une évaluation thérapeutique précoce par TEP-TDM au FDG à 2 cures d'une chimiothérapie néoadjuvante par TPF précédant un

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31

Murphy, Justin Thomas. "Radioresistance in oral squamous cell carcinoma." Thesis, University of Hull, 2008. http://hydra.hull.ac.uk/resources/hull:770.

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Head and Neck Squamous Cell Carcinoma (HNSCC) is the sixth most common cancer accounting for approximately 6% of all cancers worldwide. However the distribution across the globe varies considerably. The majority of small tumours of the oral cavity and upper aerodigestive tract, in the absence of metastatic disease, can be successfully treated with surgery or radiotherapy. Despite this most small tumours of the oral cavity are now treated with surgery as the primary treatment modality with radiotherapy being reserved for adjuvant therapy, palliation or in patients unfit for surgery. Radiotherap

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32

Hui, King-cheung, and 許景祥. "Biomarkers for esophageal squamous cell carcinoma." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2009. http://hub.hku.hk/bib/B41634020.

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Hui, King-cheung. "Biomarkers for esophageal squamous cell carcinoma." Click to view the E-thesis via HKUTO, 2009. http://sunzi.lib.hku.hk/hkuto/record/B41634020.

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Law, Bic-fai Fian. "Molecular genetics of esophageal squamous cell carcinoma." Click to view the E-thesis via HKUTO, 2006. http://sunzi.lib.hku.hk/hkuto/record/B3660446X.

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35

Ash, Cecil Samuel. "Mandibular invasion in oral squamous cell carcinoma." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp04/mq23202.pdf.

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Sun, Li. "Molecular cytogenetics of oral squamous cell carcinoma." Click to view the E-thesis via HKUTO, 2002. http://sunzi.lib.hku.hk/HKUTO/record/B38627887.

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Lim, Kue Peng. "Fibroblasts in human oral squamous cell carcinoma." Thesis, University of Bristol, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.503859.

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The tumour microenvironment is known to play an important role in tumour development and progression. The diversity and role of stromal fibroblasts in human oral cancer, however, is unknown. In this study, fibroblasts were oral cancer, however, is unknown. In this study, fibroblasts were isolated from cultures of normal oral mucosa, oral epithelial dysplasia and mortal and immortal oral carcinomas, the latter malignancy being genetically unstable. Using global gene expression profiling, we demonstrated that fibroblasts clustered according to their tissue of origin.

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38

Hu, Yingchuan, and 胡穎川. "Molecular pathogenesis of oesophageal squamous cell carcinoma." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2000. http://hub.hku.hk/bib/B31241797.

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Sun, Li, and 孫莉. "Molecular cytogenetics of oral squamous cell carcinoma." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2002. http://hub.hku.hk/bib/B36544267.

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Law, Bic-fai Fian, and 羅璧輝. "Molecular genetics of esophageal squamous cell carcinoma." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2006. http://hub.hku.hk/bib/B3660446X.

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Yap, Lee Fah. "Molecular characterization of oral squamous cell carcinoma." Thesis, University of Bristol, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.435716.

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42

Lambert, Sally Ruth. "Molecular profiling of cutaneous squamous cell carcinoma." Thesis, Queen Mary, University of London, 2010. http://qmro.qmul.ac.uk/xmlui/handle/123456789/564.

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Cutaneous squamous cell carcinoma (cSCC) is the second most common form of non-melanoma skin cancer and accounts for the majority of deaths from this disease. Its incidence is increasing rapidly, contributing significant morbidity to patients and a burden on healthcare resources. The molecular events underlying cSCC development remain largely uncharacterised, despite the well established role of ultraviolet radiation as a principal carcinogen. Genomewide analyses of the genetic changes underlying cSCC development have shown they are subject to large chromosomal aberrations, which often involve

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43

Mallipeddi, Rajeev. "Understanding squamous cell carcinoma in epidermolysis bullosa." Thesis, King's College London (University of London), 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.416097.

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44

Baldursson, Baldur. "Development of squamous cell carcinoma in venous ulcers /." Stockholm, 2000. http://diss.kib.ki.se/2000/91-628-4079-7/.

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45

Bennett, Kristi Lynn. "Methylation in head and neck squamous cell carcinoma." Columbus, Ohio : Ohio State University, 2007. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1194544327.

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46

Liu, Xiaobing. "Dysregulation of microRNAs in tongue squamous cell carcinoma." Click to view the E-thesis via HKUTO, 2008. http://sunzi.lib.hku.hk/hkuto/record/b40203499.

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Carter, S. A. "Novel cytogenetic abnormalities in cervical squamous cell carcinoma." Thesis, University of Cambridge, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.597332.

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SCC cell lines were karyotyped to identify recurrent aberrations and those providing a selective advantage in individual cases. Karyotypic heterogeneity provided evidence for ongoing chromosomal instability (CIN) in all cell lines but revealed discordance between the levels of numerical CIN (N-CIN) and structural CIN (S-CIN), supporting the notion that different mechanisms underlie these processes. This molecular cytogenetic analysis identified a novel reciprocal translocation t(8:12)(p21.3;p13.31) present in all cells of the SCC cell line MS751, indicative of a selective advantage. The rearra

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Liu, Xiaobing, and 劉小兵. "Dysregulation of microRNAs in tongue squamous cell carcinoma." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2008. http://hub.hku.hk/bib/B40203499.

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Chung, Man-fai Yvonne, and 鍾文暉. "Investigation of biomarkers in esophageal squamous cell carcinoma." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2009. http://hub.hku.hk/bib/B43704025.

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50

Yu, Zhuoyou, and 余卓由. "Role of DNAJB6 in esophageal squamous cell carcinoma." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2013. http://hdl.handle.net/10722/196454.

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Esophageal cancer (EC), which is geographically diverse, has only a 10.7% five-year survival rate. One of the histologic forms, esophageal squamous cell carcinoma (ESCC), in Hong Kong accounts for 81.5% of the total EC cases and its five-year survival rate is only ~14%, due to its high frequency of metastasis. In our previous studies, functional complementation study of chromosome 9 defects led to the discovery of a novel tumor suppressor gene, Deleted in Esophageal Cancer 1 (DEC1), mapping to 9q32. DEC1 was shown to reduce tumorigenicity in a mouse model and its expression was shown to be as

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