Academic literature on the topic 'Chronically infected'

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Journal articles on the topic "Chronically infected"

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PARAMESWARAN, N., R. M. O'HANDLEY, M. E. GRIGG, A. WAYNE, and R. C. A. THOMPSON. "Vertical transmission of Toxoplasma gondii in Australian marsupials." Parasitology 136, no. 9 (2009): 939–44. http://dx.doi.org/10.1017/s0031182009006453.

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SUMMARYTo date, little is known about the dynamics of vertical transmission of Toxoplasma gondii in Australian marsupials. Studies in mice demonstrate that vertical transmission of T. gondii is common and that chronically infected mice can transmit T. gondii to successive generations. In this study, PCR and immunohistochemistry were used to detect T. gondii in chronically infected marsupial dams and their offspring. T. gondii was detected in the unfurred pouch young of 2 out of 10 chronically infected western grey kangaroos (Macropus fuliginosus) and in the unfurred pouch young of a brush-tail
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Krajden, Mel. "Hepatitis." Canadian Journal of Infectious Diseases 12, no. 6 (2001): 329–31. http://dx.doi.org/10.1155/2001/428059.

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Worldwide, approximately 170 million people are chronically infected with hepatitis C virus (HCV) and another 350 million individuals are chronically infected with hepatitis B virus (HBV) (1,2). Canada is estimated to have 240,000 to 300,000 HCV and 200,000 to 280,000 HBV chronic carriers (3,4). Without intervention, over multiple decades, approximately 15% to 30% of chronic HBV- and HCV-infected individuals will develop cirrhosis, end-stage liver disease or liver cancer, or will require liver transplantation (1,2,5). From a public health perspective, the major challenge is how best to avoid a
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Reed, S. G., K. H. Grabstein, D. L. Pihl, and P. J. Morrissey. "Recombinant granulocyte-macrophage colony-stimulating factor restores deficient immune responses in mice with chronic Trypanosoma cruzi infections." Journal of Immunology 145, no. 5 (1990): 1564–70. http://dx.doi.org/10.4049/jimmunol.145.5.1564.

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Abstract Spleen cells from mice with chronic Trypanosoma cruzi infection generate a minimal plaque-forming response to SRBC in vitro. Addition of granulocyte-macrophage (GM)-CSF to cultures of spleen cells from chronically infected mice restored the plaque-forming cells (PFC) response to normal levels. Splenic adherent cells from chronically infected mice were deficient in their ability to reconstitute the PFC response of accessory cell-depleted normal spleen cells. Preincubation of splenic adherent cells from infected mice with GM-CSF restored their ability to reconstitute the PFC response of
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Cadogan, Elaine, Natalie Hopkins, Shay Giles, John G. Bannigan, John Moynihan, and Paul McLoughlin. "Enhanced expression of inducible nitric oxide synthase without vasodilator effect in chronically infected lungs." American Journal of Physiology-Lung Cellular and Molecular Physiology 277, no. 3 (1999): L616—L627. http://dx.doi.org/10.1152/ajplung.1999.277.3.l616.

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We hypothesized that abnormal ventilation-perfusion matching in chronically infected lungs was in part due to excess nitric oxide (NO) production after upregulation of inducible NO synthase (iNOS) expression. Rats were anesthetized and inoculated intratracheally with Pseudomonas aeruginosa incorporated into agar beads (chronically infected) or with sterile agar beads (placebo inoculated) and killed 10–15 days later. Immunohistochemistry demonstrated increased expression of iNOS and reduced expression of endothelial NOS (eNOS) in chronically infected compared with placebo-inoculated or noninocu
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Olds, G. R., S. el Meneza, A. F. Mahmoud, and T. F. Kresina. "Differential immunoregulation of granulomatous inflammation, portal hypertension, and hepatic fibrosis in murine schistosomiasis mansoni." Journal of Immunology 142, no. 10 (1989): 3605–11. http://dx.doi.org/10.4049/jimmunol.142.10.3605.

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Abstract The present study investigates the immunoregulation of hepatic fibrosis in experimental murine schistosomiasis. Disease parameters measured were portal pressure, hepatic granuloma area, hepatic interstitial collagen, and glycosaminoglycans. C57BL/6 mice were infected with 25 Schistosoma mansoni cercariae and administered splenocytes or serum derived from uninfected mice or chronically infect syngeneic mice at 6 and 7 wk of infection. Immunologically mediated modulation was noted in animals receiving splenocytes derived from chronically infected mice. Both a reduction in portal pressur
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Feehally, John. "Glomerulonephritis from a chronically infected implanted device." Lancet 386, no. 10010 (2015): 2364. http://dx.doi.org/10.1016/s0140-6736(15)00826-0.

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Basaras, M., E. Arrese, S. Blanco, M. Sota, B. de las Heras, and R. Cisterna. "Hepatitis B Virus in Chronically Infected Patients." International Journal of Infectious Diseases 12 (December 2008): e421-e422. http://dx.doi.org/10.1016/j.ijid.2008.05.1236.

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Tepekule, Burcu, Anthony Hauser, Viacheslav N. Kachalov, et al. "Assessing the potential impact of transmission during prolonged viral shedding on the effect of lockdown relaxation on COVID-19." PLOS Computational Biology 17, no. 1 (2021): e1008609. http://dx.doi.org/10.1371/journal.pcbi.1008609.

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A key parameter in epidemiological modeling which characterizes the spread of an infectious disease is the generation time, or more generally the distribution of infectiousness as a function of time since infection. There is increasing evidence supporting a prolonged viral shedding window for COVID-19, but the transmissibility in this phase is unclear. Based on this, we develop a generalized Susceptible-Exposed-Infected-Resistant (SEIR) model including an additional compartment of chronically infected individuals who can stay infectious for a longer duration than the reported generation time,
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Obaid, Mustafa A., and A. M. Elaiw. "Stability of Virus Infection Models with Antibodies and Chronically Infected Cells." Abstract and Applied Analysis 2014 (2014): 1–12. http://dx.doi.org/10.1155/2014/650371.

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Two virus infection models with antibody immune response and chronically infected cells are proposed and analyzed. Bilinear incidence rate is considered in the first model, while the incidence rate is given by a saturated functional response in the second one. One main feature of these models is that it includes both short-lived infected cells and chronically infected cells. The chronically infected cells produce much smaller amounts of virus than the short-lived infected cells and die at a much slower rate. Our mathematical analysis establishes that the global dynamics of the two models are d
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dos Santos, R. R., M. A. Rossi, J. L. Laus, J. S. Silva, W. Savino, and J. Mengel. "Anti-CD4 abrogates rejection and reestablishes long-term tolerance to syngeneic newborn hearts grafted in mice chronically infected with Trypanosoma cruzi." Journal of Experimental Medicine 175, no. 1 (1992): 29–39. http://dx.doi.org/10.1084/jem.175.1.29.

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The contribution of autoimmunity in the genesis of chronic Chagas' heart pathology is not clear. In the present study, we show that: (a) BALB/c mice chronically infected with Trypanosoma cruzi reject syngeneic newborn hearts; (b) in vivo treatment with anti-CD4 but not anti-CD8 monoclonal antibodies (mAbs) abrogates rejection; (c) CD4+ T cells from chronically infected mice proliferate in vitro to syngeneic myocardium antigens and induce heart graft destruction when injected in situ; (d) anti-CD4 treatment of chronically infected mice establishes long-term tolerance to syngeneic heart grafts;
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Dissertations / Theses on the topic "Chronically infected"

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Bennett, Molly Marie Bennett. "Design, Fabrication, and Characterization of Electroceutical Bandages for Treatment of Chronically Infected Wounds." The Ohio State University, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=osu1462837586.

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Rahn, Wibke. "Molecular analysis of Helicobacter pylori-associated gastric inflammation in chronically infected and immune mice." [S.l.] : [s.n.], 2003. http://deposit.ddb.de/cgi-bin/dokserv?idn=972341781.

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Roulston, Anne. "Regulation of NF-kB dependent cytokine gene expression in chronically HIV-1 infected myeloid cells." Thesis, McGill University, 1994. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=28902.

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Myeloid cells are important reservoirs of HIV-1 infection. In response to pathogenic agents, macrophages secrete inflammatory cytokines which can stimulate viral replication and contribute to AIDS pathogenesis. Two promonocytic cell models were used to investigate the relationship between NF-$ kappa$B dependent cytokine gene expression, differentiation, and HIV infection: the U937 and PLB-985 cell lines and their chronically infected counterparts U9-IIIB and PLB-IIIB. Chronic HIV-1 infection of U9-IIIB cells did not generally lead to constitutive transcription of cytokine genes. However, when
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Banerjee, Camellia Tina. "Muscle ageing and anabolic response in the context of healthy and chronically HIV infected individuals." Thesis, Boston University, 2012. https://hdl.handle.net/2144/12275.

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Thesis (Ph.D.)--Boston University PLEASE NOTE: Boston University Libraries did not receive an Authorization To Manage form for this thesis or dissertation. It is therefore not openly accessible, though it may be available by request. If you are the author or principal advisor of this work and would like to request open access for it, please contact us at open-help@bu.edu. Thank you.<br>In the last thirty years of the HIV epidemic, HIV has transitioned from a deadly to a chronic, manageable disease wherein infected individuals are living longer. However, despite the efficacy of antiretroviral
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Desai, Annika. "Changes in Binding Properties of Helicobacter pylori Isolated over time from a Chronically Infected Patient." Thesis, Umeå universitet, Institutionen för odontologi, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-129986.

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Helicobacter pylori infects over 50 % of the world’s population, causing gastritis, and in some cases, peptic ulcer disease and gastric cancer. Adherence to the gastric surface occurs primarily through H. pylori outer membrane proteins (HOPs) and is essential for bacterial survival and establishment of infection. The Blood group Antigen-Binding Adhesin (BabA) is the best-characterized attachment protein, mediating adherence by binding to fucosylated carbohydrate structures on the surface of the gastric epithelium. H. pylori is highly adaptable to environmental changes that occur during stomach
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Calascibetta, F. "ANALYSIS OF VIRAL RESERVOIRS IN CHRONICALLY SIV-INFECTED SOOTY MANGABEYS TREATED WITH COMBINATION ANTIRETROVIRAL THERAPY (CART)." Doctoral thesis, Università degli Studi di Milano, 2015. http://hdl.handle.net/2434/252682.

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Background: Human Immunodeficiency Virus (HIV), the causative pathogen of Acquired Immunodeficiency Syndrome (AIDS), continues to be a major global public health issue. Although, potent antiretroviral therapy (ART) has dramatically reduced the morbidity and mortality in HIV-infected individuals, one of the most consistent obstacles to HIV eradication is the presence of stable viral reservoirs of latently infected cells. The aim of the present study is to understand the mechanisms of the complex virus-host interactions that lead to persistent infection, and to achieve the ideal combination of t
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Chuang, W. C. M. "Molecular and immunological study of genotype 2 Hepatitis C virus infection in chronically infected and recovered blood donors." Thesis, University of Cambridge, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.597684.

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Recovery from Hepatitis C virus (HCV) infection is considered infrequent (<20%) in Western populations but reaches 50% in West Africa where genotype 2 infection is predominant. The first objective of this project was to investigate the role of cellular response and host genetics involved in this phenomenon. Plasma samples from 104 Ghanaian blood donors reactive with anti-HCV assays were collected. 81% of subjects with chronic infection carried genotype 2 HVC. Cellular immune responses were studied in frozen peripheral blood mononuclear cell samples from 35 cases. HLA-A, -B and –DR types were d
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CAUCCI, Sara. "Replicative capacity and phenotypic sensitivity to antiretroviral compounds of HIV-1 strains from recently infected and chronically treated patients." Doctoral thesis, Università Politecnica delle Marche, 2020. http://hdl.handle.net/11566/273393.

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La terapia antiretrovirale purtroppo può indurre la selezione di ceppi virali resistenti ai farmaci, che possono essere trasmessi ad altre persone. In questo studio è stato messo a punto un saggio fenotipico per comprendere la dinamica evolutiva delle resistenze trasmesse, confrontando la capacità replicativa (RC), e quindi il potenziale epidemico, conferiti dai geni della proteasi (PR) e della trascrittasi inversa (RT) di ceppi virali provenienti da pazienti con infezione recente. Inoltre il saggio fenotipico è stato impiegato per studiare l'influenza del background genetico del gene dell’int
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Afridi, Suliman Qadir Verfasser], Ulrike [Akademischer Betreuer] [Protzer-Knolle, Markus [Gutachter] Gerhard, and Sabrina [Gutachter] Schreiner. "Genotypic and phenotypic analysis of norovirus evolution in chronically infected patients / Suliman Qadir Afridi ; Gutachter: Markus Gerhard, Sabrina Schreiner ; Betreuer: Ulrike Protzer." München : Universitätsbibliothek der TU München, 2019. http://d-nb.info/1206687312/34.

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TRIPODI, GIANLUCA. "Integration of hepatitis B virus DNA in chronically infected patients." Doctoral thesis, 2017. http://hdl.handle.net/11570/3104198.

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Abstract Background: Hepatitis B virus (HBV) infection is the main risk factor for hepatocellular carcinoma (HCC) worldwide. Several factors contribute to the development of cancer. Integration of HBV DNA into the human genome may activate genes that promote, or disrupt genes that normally suppress, cell proliferation, and has been found in >80% of HBV-related HCC. Some studies have however failed to confirm an association between HCC and integration at putativeoncogenic sites, but instead found similar integrations in tumourous and non-tumourous tissue. Thus, the rate of integration durin
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Books on the topic "Chronically infected"

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Matsukuru, Makoto. Phosphorothioate analogs of oligodeoxynucleotide inhibit viral replication of human immunodeficiency virus (HIV): Inhibition of de novo infection in uninfected cells and regulation of viral expression in chronically infected cells. National Cancer Institute, Office of Cancer Communications, 1988.

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Martagon-Villamil, Jose, and Daniel J. Skiest. Clinical Syndromes and Differential Diagnosis in the HIV-Infected Patient. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190493097.003.0011.

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Acute HIV infection is often missed but should be recognized. Most chronically infected individuals are asymptomatic. However, some patients with chronic HIV infection may present with certain clinical and laboratory abnormalities prior to the diagnosis of an opportunistic infection. HIV wasting syndrome is infrequently diagnosed in the era of antiretroviral therapy (ART). Recognition of HIV wasting is important because it carries adverse prognostic implications. Management includes a multifaceted approach, including ART, lifestyle and nutritional support, appetite stimulation, and possibly ho
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Honegger, Jonathan R. Hepatitis C Virus. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190604813.003.0005.

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An estimated 185 million individuals have been infected with hepatitis C virus (HCV) worldwide. Although often clinically silent for decades, chronic HCV infection predisposes to late-onset complications, including liver cirrhosis and hepatocellular carcinoma. Mother-to-child transmission (MTCT) of HCV affects approximately 5% of children born to viremic mothers and is the primary route of HCV infection in young children. While some vertically acquired HCV infections are resolved during the first years of life, many persist indefinitely. Chronically infected children tend to be asymptomatic an
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Pollock, Rob. Total hip replacement: modes of failure. Oxford University Press, 2011. http://dx.doi.org/10.1093/med/9780199550647.003.007010.

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♦ Total hip replacements (THRs) may fail in various ways. They may become infected, they may be subject to aseptic loosening, they may dislocate, or a periprosthetic fracture may occur. The patient with a failed THR must be thoroughly assessed before treatment is contemplated♦ Infection may be acute or chronic. Assessment involves clinical assessment, plain radiographs, blood tests (C-reactive protein and erythrocyte sedimentation rate), hip aspiration, and, sometimes, nuclear medicine. The acutely infected hip may be treated with one-stage revision. This involves thorough lavage, debridement,
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Majid, Adrian, and Bruce L. Gilliam. Future Antiretrovirals, Immune-Based Strategies, and Therapeutic Vaccines. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190493097.003.0023.

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Highly active antiretroviral therapy remains the mainstay of treatment for patients chronically infected with HIV. Novel drugs, both within existing classes and new ones, are in various stages of development and testing. New medications within existing classes of antiretroviral agents are in clinical trials and will likely offer activity against resistant HIV-1 strains and provide alternatives for combination pill therapy. Novel therapeutics including oral attachment inhibitors and monoclonal antibody treatments continue to show efficacy against HIV-1 and progress in clinical trials. Tenofovir
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Clement, Jan, and Piet Maes. Hantaviral infections. Edited by Vivekanand Jha. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199592548.003.0188_update_001.

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Hantavirus disease is a viral zoonosis, caused by inhalation of infectious aerosolized excreta from chronically infected rodents, which are both the reservoir and the vector of different hantavirus species. Hantavirus infections manifest mainly as haemorrhagic fever with renal syndrome and hantavirus pulmonary syndrome, which traditionally but incorrectly were thought to be caused by exclusively Old World hantaviruses and New World hantaviruses, respectively.Hantavirus diseases are characterized by non-specific flu-like symptoms, followed by a sometimes lethal capillary leak syndrome, haemorrh
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Kourtis, Athena P., Shruti Chandramouli, Gonzague Jourdain, and Marc Bulterys. Hepatitis B Virus. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190604813.003.0004.

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Hepatitis B virus (HBV) is the most common cause of chronic viral hepatitis and hepatocellular carcinoma in the world. Worldwide, more than 250 million people are chronically infected with HBV, causing nearly 780,000 deaths each year, and mother-to-child transmission (MTCT) accounts for more than one-third of chronic HBV infections. Universal vaccination in neonates is the most effective strategy for eliminating infections worldwide. Maternal antiviral treatment during the antepartum/postpartum period for mothers with high HBV viral loads is effective in preventing HBV MTCT. Full immunization
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Clement, Jan. Acute kidney injury and hantavirus disease. Edited by Norbert Lameire. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199592548.003.0242_update_001.

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Hantavirus disease or at least its renal form, the so-called haemorrhagic fever with renal syndrome is the only globally emerging acute kidney injury (AKI) form, and currently without doubt the most underestimated form of community-acquired AKI. Hantavirus disease is a viral zoonosis, caused by inhalation of infectious aerosolized excreta from chronically infected rodents, which are both the reservoir and the vector of different hantavirus species. Clinical presentation consists of sudden flu-like symptoms (fever, headache, myalgia), followed by gastrointestinal discomfort and AKI, often with
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Book chapters on the topic "Chronically infected"

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Garbuglia, A. R., A. Manzin, A. Budkowska, G. Taliani, C. Delfini, and G. Carloni. "PCR analysis of HBV infected sera: relationship between expression of pre-S antigens and viral replication." In Chronically Evolving Viral Hepatitis. Springer Vienna, 1992. http://dx.doi.org/10.1007/978-3-7091-5633-9_23.

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Gomez, Miguel M., Jorge Manrique, and Javad Parvizi. "Periprosthetic Infection: Management of Chronically Infected Total Knee Arthroplasty." In Complex Primary and Revision Total Knee Arthroplasty. Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-18350-3_9.

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Nigro, G., G. Taliani, A. Krzysztofiak, et al. "Multiple viral infections in HIV-infected children with chronically-evolving hepatitis." In Research in Chronic Viral Hepatitis. Springer Vienna, 1993. http://dx.doi.org/10.1007/978-3-7091-9312-9_24.

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Jolicoeur, P., and L. Lamontagne. "Impairment of Bone Marrow Pre-B and B Cells in MHV3 Chronically-Infected Mice." In Advances in Experimental Medicine and Biology. Springer US, 1995. http://dx.doi.org/10.1007/978-1-4615-1899-0_33.

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Chao, Chun C., Genya Gekker, Wen S. Sheng, Shuxian Hu, Philip S. Portoghese, and Phillip K. Peterson. "Endogenous Opioid Peptides Suppress Cytokine-Mediated Upregulation of HIV-1 Expression in the Chronically Infected Promonocyte Clone U1." In The Brain Immune Axis and Substance Abuse. Springer US, 1995. http://dx.doi.org/10.1007/978-1-4615-1951-5_10.

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Woodward, Will. "Nutritional support." In Perioperative Medicine. Oxford University PressOxford, 2006. http://dx.doi.org/10.1093/oso/9780199211739.003.0018.

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Abstract Many surgical patients are undernourished and at risk of developing overt nutritional deficiency. Undernutrition is associated with increases in the risk of postoperative infection, the length of hospital stay and mortality. Patients at particular risk are those who are: already undernourished on admission to hospital (elderly, unsupported, poor, self-caring, chronically infected, alcoholic, anorexic, nauseated, or vomiting owing to disease process, e.g. upper GI cancer) presenting acutely with sepsis (e.g. emergency surgery for bowel perforation, urological sepsis) with major trauma
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Umutesi, Justine, Janvier Serumondo, and Claude Mambo Muvunyi. "Pitfalls in HBV Treatment and Management." In Hepatitis B Virus - Pathogenesis and Therapeutic Approaches [Working Title]. IntechOpen, 2024. https://doi.org/10.5772/intechopen.1005795.

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Although new infections due to viral hepatitis are declining as a result of numerous efforts to prevent and control hepatitis B virus (HBV), it remains the second leading infectious cause of death after tuberculosis. The lack of contextual management of HBV and its consequences may be one of the many reasons for these deaths. Drugs such as tenofovir disoproxil fumarate (TDF) are effective but have serious side effects, including bone and kidney dysfunction, which make survival more uncertain. Tenofovir alafenamide (TAF) has proved safer, more tolerant and more stable in plasma than TDF, but it
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Oxford, John, Paul Kellam, and Leslie Collier. "Antiviral chemotherapy." In Human Virology. Oxford University Press, 2016. http://dx.doi.org/10.1093/hesc/9780198714682.003.0031.

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This chapter talks about a number of important virus diseases–such as measles, poliomyelitis, yellow fever, and rubella–which can be kept under very good control with live virus vaccines. However, it is difficult to imagine the development of successful vaccines for many other viruses due to the multiplicity of serotypes, or variability or complexity of their antigenic structure. Other viruses such as hepatitis B and C have chronically infected millions, and vaccines cannot break these established infections: they are only able to prevent new infections in the case of hepatitis B. Finally, som
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Jyothimol, G. "Parasites of Urogenital Tract of Goat." In Parasitic Diseases of Goats. BENTHAM SCIENCE PUBLISHERS, 2024. https://doi.org/10.2174/9789815256628124010007.

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Goats are an important part of the agrarian economy in different parts of the world. They are known as poor man’s cows. Some of the parasitic infections can lead to a reduction in performance and reproductive failures in goats. Toxoplasma gondii is one among them, and only one reported parasite affecting the urogenital tract of goats. Goats usually harbor the intermediate stages of this organism in different body tissues. It causes abortion in goats if pregnant goats are infected during any stage of pregnancy. This lead to great economic loss to the farmer. However, abortions in goats may not
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Oxford, John, Paul Kellam, and Leslie Collier. "Hepadnaviruses: hepatitis B and D." In Human Virology. Oxford University Press, 2016. http://dx.doi.org/10.1093/hesc/9780198714682.003.0028.

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This chapter discusses the hepadnaviruses and considers the estimation of WHO that two billion people have been exposed to and 350 million people worldwide are chronically infected by hepatitis B. In some countries more than 10% of the population is afflicted, and surveys of the global burden of disease HBV rank it as the tenth leading cause of death, which makes it a major public health priority. The chapter mentions that there are excellent recombinant vaccines. Over 180 countries of the world have started a Universal Vaccination Campaign for neonates to blunt the clinical effect of the viru
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Conference papers on the topic "Chronically infected"

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Pukhalskaya, Daria, Vassiliy Shmarin, Sergey Semykin, et al. "Changes in local and systemic inflammatory markers in cystic fibrosis patients chronically infected with Burkholderia cepacia complex." In ERS International Congress 2020 abstracts. European Respiratory Society, 2020. http://dx.doi.org/10.1183/13993003.congress-2020.689.

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Christopher, Kintu. "LB1.65 Frequency of broadly neutralising antibodies in hiv-1 chronically infected individuals in ugandan clades a & d." In STI and HIV World Congress Abstracts, July 9–12 2017, Rio de Janeiro, Brazil. BMJ Publishing Group Ltd, 2017. http://dx.doi.org/10.1136/sextrans-2017-053264.170.

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Heim, K., A. Schuch, E. Salimi Alizei, et al. "Phenotypic and functional differences of HBVcore- versus HBVpolymerase-specific CD8+ T cells in chronically HBV-infected patients with low viral load." In 35. Jahrestagung der Deutschen Arbeitsgemeinschaft zum Studium der Leber. Georg Thieme Verlag KG, 2019. http://dx.doi.org/10.1055/s-0038-1677258.

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Smith, WD, RA Murphy, A. Simbo, et al. "M2 Pseudomonas aeruginosa (Pa) biofilm-forming potential and metabolomic phenotypes differ between chronically infected patients with cystic fibrosis (CF) and non-CF bronchiectasis (Bx)." In British Thoracic Society Winter Meeting 2019, QEII Centre, Broad Sanctuary, Westminster, London SW1P 3EE, 4 to 6 December 2019, Programme and Abstracts. BMJ Publishing Group Ltd and British Thoracic Society, 2019. http://dx.doi.org/10.1136/thorax-2019-btsabstracts2019.410.

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Chalmers, James D., Bruce Thompson, Juergen Froehlich, et al. "Effect of prior year pulmonary exacerbation (PE) frequency on response to ARD-3150 in patients with non-cystic fibrosis bronchiectasis (NCFB) chronically infected with Pseudomonas aeruginosa (PA)." In ERS International Congress 2018 abstracts. European Respiratory Society, 2018. http://dx.doi.org/10.1183/13993003.congress-2018.pa2675.

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M. Essa, Israa. "Serological Investigation of Equine Toxoplasmosis and Association to Prevalence Factors in Basra Province, Iraq." In XI. International Scientific Congress of Pure, Applied and Technological Sciences (MINAR Congress). Rimar Academy, 2024. https://doi.org/10.47832/minarcongress11-5.

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Background: Toxoplasmosis is one of the most prevalent and neglected diseases which caused by a singlecelled parasite called Toxoplasma gondii resulting in economically variable looses in different animals and marked public health problem in human, particularly women. Aims: This study aims to identify serological prevalence of acute and chronic infection in native equine, horse and donkey, in Basra province (Iraq) using the qualitative enzyme-linked immunosorbent assay (ELISA). Materials and methods: A total of 184 equine animals including 39 horses and 145 donkeys were selected randomly from
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Reports on the topic "Chronically infected"

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Polly, Jr, and David W. New Bone Foundation in a Chronically-Infected Segmental Defect in the Rat Femur Treatment with BMP-2 and Local Antibiotic. Defense Technical Information Center, 2008. http://dx.doi.org/10.21236/ada510063.

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Yogev, David, Ricardo Rosenbusch, Sharon Levisohn, and Eitan Rapoport. Molecular Pathogenesis of Mycoplasma bovis and Mycoplasma agalactiae and its Application in Diagnosis and Control. United States Department of Agriculture, 2000. http://dx.doi.org/10.32747/2000.7573073.bard.

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Mycoplasma bovis and M. agalactiae are two phylogenetically related mycoplasmas which cause economically significant diseases in their respective bovine or small ruminant hosts. These organisms cause persistent asymptomatic infections that can result in severe outbreaks upon introduction of carrier animals into susceptible herds. Little is known about the mechanisms underlying mycoplasma-host interaction, variation in virulence, or of the factors enabling avoidance of the host immune system. In recent years it has become apparent that the ability of pathogenic microorganisms to rapidly alter s
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Dawson, William O., and Moshe Bar-Joseph. Creating an Ally from an Adversary: Genetic Manipulation of Citrus Tristeza. United States Department of Agriculture, 2004. http://dx.doi.org/10.32747/2004.7586540.bard.

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Citrus is one of the major agricultural crops common to Israel and the United States, important in terms of nutrition, foreign exchange, and employment. The economy of both citrus industries have been chronically plagued by diseases caused by Citrus tristeza virus (CTV). The short term solution until virus-resistant plants can be used is the use of mild strain cross-protection. We are custom designing "ideal" protecting viruses to immunize trees against severe isolates of CTV by purposely inoculating existing endangered trees and new plantings to be propagated as infected (protected) citrus bu
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Bacharach, Eran, and Sagar Goyal. Generation of Avian Pneumovirus Modified Clones for the Development of Attenuated Vaccines. United States Department of Agriculture, 2008. http://dx.doi.org/10.32747/2008.7696541.bard.

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Abstract (one page maximum, single spaced), include: List the original objectives, as defined in the approved proposal, and any revisions made at the beginning or during the course of project: The main goal described in our original proposal has been the development of a molecular infectious clone of the avian metapneumovirus subtype B (aMPV-B) and the modification of this clone to create mutated viruses for the development of attenuated vaccines. The Achievements and Appendix/Part I sections of this report describes the accomplishments in creating such a molecular clone. These sections also c
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