Academic literature on the topic 'Dopamine receptors'

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Journal articles on the topic "Dopamine receptors"

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Jose, P. A., J. R. Raymond, M. D. Bates, A. Aperia, R. A. Felder, and R. M. Carey. "The renal dopamine receptors." Journal of the American Society of Nephrology 2, no. 8 (1992): 1265–78. http://dx.doi.org/10.1681/asn.v281265.

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Dopamine is an endogenous catecholamine that modulates many functions including behavior, movement, nerve conduction, hormone synthesis and release, blood pressure, and ion fluxes. Dopamine receptors in the brain have been classically divided into D1 and D2 subtypes, based on pharmacological data. However, molecular biology techniques have identified many more dopamine receptor subtypes. Several of the receptors cloned from the brain correspond to the classically described D1 and D2 receptors. Several D1 receptor subtypes have been cloned (D1A, D1B, and D5) and are each coupled to the stimulat
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Hussain, Tahir, and Mustafa F. Lokhandwala. "Renal Dopamine Receptors and Hypertension." Experimental Biology and Medicine 228, no. 2 (2003): 134–42. http://dx.doi.org/10.1177/153537020322800202.

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Dopamine has been recognized as an important modulator of central as well as peripheral physiologic functions in both humans and animals. Dopamine receptors have been identified in a number of organs and tissues, which Include several regions within the central nervous system, sympathetic ganglia and postganglionic nerve terminals, various vascular beds, the heart, the gastrointestinal tract, and the kidney. The peripheral dopamine receptors influence cardiovascular and renal function by decreasing afterload and vascular resistance and promoting sodium excretion. Within the kidney, dopamine re
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Awenowicz, Patrick W., and Linda L. Porter. "Local Application of Dopamine Inhibits Pyramidal Tract Neuron Activity in the Rodent Motor Cortex." Journal of Neurophysiology 88, no. 6 (2002): 3439–51. http://dx.doi.org/10.1152/jn.00078.2002.

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Cortical neurons respond in a variety of ways to locally applied dopamine, perhaps because of the activation of different receptors within or among subpopulations of cells. This study was conducted to assess the effects of dopamine and the receptor subtypes that mediate the responses of a specific population of neurons, the pyramidal tract neurons (PTNs) in the rodent motor cortex. The specific subfamilies of dopamine receptors expressed by PTNs also were determined. PTNs were identified by antidromic stimulation in intact animals. Extracellular recordings of their spontaneous activity and glu
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Felder, R. A., C. C. Felder, G. M. Eisner, and P. A. Jose. "The dopamine receptor in adult and maturing kidney." American Journal of Physiology-Renal Physiology 257, no. 3 (1989): F315—F327. http://dx.doi.org/10.1152/ajprenal.1989.257.3.f315.

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Dopamine, like other neurotransmitters, exerts its biological effects by occupation of specific receptor subtypes. The dopamine receptors in the central nervous system and certain endocrine organs are classified into the D1/D2 subtypes. Outside the central nervous system, the dopamine receptors are classified into the DA1/DA2 subtypes. The D1/D2 and DA1/DA2 receptor have marked similarities and some differences, the most notable of which is the lower affinity of the DA dopamine compared with the D dopamine receptor. DA1 receptor activation increases renal blood flow (RBF); stimulation of DA1 a
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Yamamoto, Kei, Romain Fontaine, Catherine Pasqualini, and Philippe Vernier. "Classification of Dopamine Receptor Genes in Vertebrates: Nine Subtypes in Osteichthyes." Brain, Behavior and Evolution 86, no. 3-4 (2015): 164–75. http://dx.doi.org/10.1159/000441550.

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Dopamine neurotransmission regulates various brain functions, and its regulatory roles are mediated by two families of G protein-coupled receptors: the D1 and D2 receptor families. In mammals, the D1 family comprises two receptor subtypes (D1 and D5), while the D2 family comprises three receptor subtypes (D2, D3 and D4). Phylogenetic analyses of dopamine receptor genes strongly suggest that the common ancestor of Osteichthyes (bony jawed vertebrates) possessed four subtypes in the D1 family and five subtypes in the D2 family. Mammals have secondarily lost almost half of the ancestral dopamine
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Chazot, P. L., A. J. Doherty, and P. G. Strange. "Antisera specific for D2 dopamine receptors." Biochemical Journal 289, no. 3 (1993): 789–94. http://dx.doi.org/10.1042/bj2890789.

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Antisera have been raised against two peptides from the sequence of D2 dopamine receptors: peptide 1 from the predicted second extracellular loop and peptide 2 from the predicted third intracellular loop. The antisera recognize specifically a 95 kDa band in Western blots of several bovine brain regions, which corresponds to the denatured D2 dopamine receptor, whereas in recombinant CHO cells expressing D2 dopamine receptors a 80 kDa band is seen. The antisera immunoprecipitate 10-20% of the D2 dopamine receptors from soluble preparations of bovine brain. The antisera recognize D2 dopamine rece
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Zeng, Chunyu, and Pedro A. Jose. "Dopamine Receptors." Hypertension 57, no. 1 (2011): 11–17. http://dx.doi.org/10.1161/hypertensionaha.110.157727.

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Zapata, Agustin, Bronwyn Kivell, Yang Han, et al. "Regulation of Dopamine Transporter Function and Cell Surface Expression by D3 Dopamine Receptors." Journal of Biological Chemistry 282, no. 49 (2007): 35842–54. http://dx.doi.org/10.1074/jbc.m611758200.

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D3 dopamine receptors are expressed by dopamine neurons and are implicated in the modulation of presynaptic dopamine neurotransmission. The mechanisms underlying this modulation remain ill defined. The dopamine transporter, which terminates dopamine transmission via reuptake of released neurotransmitter, is regulated by receptor- and second messenger-linked signaling pathways. Whether D3 receptors regulate dopamine transporter function is unknown. We addressed this issue using a fluorescent imaging technique that permits real time quantification of dopamine transporter function in living singl
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Sunahara, Roger K., Philip Seeman, Hubert H. M. Van Tol, and Hyman B. Niznik. "Dopamine Receptors and Antipsychotic Drug Response." British Journal of Psychiatry 163, S22 (1993): 31–38. http://dx.doi.org/10.1192/s000712500029257x.

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Dopamine receptors have been divided into two major types – D1 and D2 – based primarily on pharmacological and biochemical criteria. Recent advances in the molecular biology of the dopamine receptor system have allowed the identification and characterisation of at least five distinct neuronal dopamine receptor genes (D1 to D5). These genes encode dopamine receptors belonging to the D1 receptor family, termed D1 and D5, and three D2-like receptors, termed D2, D3 and D4. These receptors are distinguished on the basis of their primary structure, chromosomal location, mRNA size and tissue distribu
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Myslivecek, Jaromir. "Dopamine and Dopamine-Related Ligands Can Bind Not Only to Dopamine Receptors." Life 12, no. 5 (2022): 606. http://dx.doi.org/10.3390/life12050606.

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The dopaminergic system is one of the most important neurotransmitter systems in the central nervous system (CNS). It acts mainly by activation of the D1-like receptor family at the target cell. Additionally, fine-tuning of the signal is achieved via pre-synaptic modulation by the D2-like receptor family. Some dopamine drugs (both agonists and antagonists) bind in addition to DRs also to α2-ARs and 5-HT receptors. Unfortunately, these compounds are often considered subtype(s) specific. Thus, it is important to consider the presence of these receptor subtypes in specific CNS areas as the functi
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Dissertations / Theses on the topic "Dopamine receptors"

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Hilditch, A. "Pharmacological characterisation of peripheral dopamine receptors." Thesis, Open University, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.352607.

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Kim, Douglas S. "Dopamine and adenosine receptor function in adult and developing dopamine-deficient mice /." Thesis, Connect to this title online; UW restricted, 2002. http://hdl.handle.net/1773/5063.

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Obray, J. Daniel. "Peripheral Dopamine 2 Receptors Both Modulate Central Dopamine Release and Adopt in a Similar Manner to that of Central Dopamine 2 Receptors." BYU ScholarsArchive, 2020. https://scholarsarchive.byu.edu/etd/8983.

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Alcohol use disorder is a debilitating disorder affecting nearly 5% of people in the United States. Despite the prevalence of alcohol use disorder few affected individuals seek treatment and of those who do many will relapse. This highlights a need to develop new treatments for alcohol use disorder that are both more accessible and more effective. This dissertation characterizes a novel pathway involved in ethanol enhancement of dopamine levels in the nucleus accumbens as well as investigating alterations in dopamine 2 receptor expression and function following an acute dose of ethanol. This w
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Evans, Anthony Mark. "Dopamine receptors of the cockroach salivary gland." Thesis, University of Edinburgh, 1990. http://hdl.handle.net/1842/27986.

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A study has been made of the secretory response and the electrical reponse (a hyperpolarization followed by a depolarization) mediated by dopamine receptors of the cockroach (<i>Nauphoeta cinerea</i> Olivier) salivary gland <i>in-vitro</i>. Although domperidone did not inhibit the electrical response to dopamine, three other actions were observed: one, post-synaptic, led to the potentiation of the hyperpolarization; this action was shared by (±)sulpiride. A separate post-synaptic action resulted in the inhibition of the depolarizing phase of the response. Finally a pre-synaptic action led to t
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Hollis, Clare M. "Central and peripheral D←1 dopamine receptors." Thesis, University of Kent, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.292301.

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Clark, Kenneth Lyle. "Pharmacology of renal dopamine and angiotensin receptors." Thesis, Open University, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.293275.

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Dopamine and angiotensin II (Ang II) are naturally occurring molecules with profound but contrasting effects in the kidney. This study aimed to increase knowledge of the pharmacology and physiology of renal dopamine and angiotensin receptors. Little evidence was found to the presence of dopamine DA1 receptors, mediating dilatation, or angiotensin receptors, mediating constriction, in canine isolated main branch, interlobar, or arcuate renal artery rings. However, in anaesthetised dogs, renal vascular angiotensin and dopamine receptors were clearly demonstrated, suggesting that they are located
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Torvinen, Maria. "Adenosine receptor/dopamine receptor interactions : molecular and biochemical aspects /." Stockholm, 2002. http://diss.kib.ki.se/2002/91-7349-298-1/.

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Tong, Huaxia. "Modulation of NMDA receptor activity by dopamine receptors in the rat striatum." Thesis, University College London (University of London), 2006. http://discovery.ucl.ac.uk/1445880/.

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NMDA receptors are of particular importance in the control of synaptic strength and integration of synaptic activity. Dopamine receptor modulation of NMDA receptors in the striatum may influence the efficacy of synaptic transmission in the cortico-striatal pathway (Calabresi et al., 2000c Centonze et al., 2003) and if so, this modulation will be lost in Parkinson's disease. This change may be an important factor in the changes in the basal ganglia neural network that occur in Parkinson's Disease. In this thesis I have studied dopamine D1 and D2 receptor modulation of NMDA receptors in medium s
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Heusner, Carrie L. "Genetic analysis of striatal glutamate-dopamine interactions /." Thesis, Connect to this title online; UW restricted, 2005. http://hdl.handle.net/1773/9212.

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Oak, James N. "Characterization of epitope-tagged dopamine D¦4 receptors." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape9/PQDD_0001/MQ45554.pdf.

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Books on the topic "Dopamine receptors"

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Ian, Creese, and Fraser Claire M, eds. Dopamine receptors. A.R. Liss, 1987.

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Neve, Kim A., ed. The Dopamine Receptors. Humana Press, 2010. http://dx.doi.org/10.1007/978-1-60327-333-6.

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Neve, Kim A., and Rachael L. Neve, eds. The Dopamine Receptors. Humana Press, 1997. http://dx.doi.org/10.1007/978-1-4757-2635-0.

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A, Neve Kim, and Neve Rachael L, eds. The dopamine receptors. Humana Press, 1997.

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Goldstein, Menek, Kjell Fuxe, and Irving Tabachnick, eds. Central D1 Dopamine Receptors. Springer US, 1988. http://dx.doi.org/10.1007/978-1-4899-2723-1.

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Symposium on Central D₁ Dopamine Receptors (1986 New York, N.Y.). Central D₁ dopamine receptors. Plenum Press, 1988.

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Tiberi, Mario. Dopamine receptor technologies. Humana Press, 2015.

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L, Waddington John, ed. D1:D2 dopamine receptor interactions. Academic Press, 1993.

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R, Breese George, and Creese Ian, eds. Neurobiology of central Dl-dopamine receptors. Plenum Press, 1986.

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R, Breese George, and Creese Ian, eds. Neurology of central D1-dopamine receptors. Plenum, 1986.

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Book chapters on the topic "Dopamine receptors"

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Nichols, David E. "Dopamine Receptor Subtype-Selective Drugs: D1-Like Receptors." In The Dopamine Receptors. Humana Press, 2009. http://dx.doi.org/10.1007/978-1-60327-333-6_4.

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Prante, Olaf, Miriam Dörfler, and Peter Gmeiner. "Dopamine Receptor Subtype-Selective Drugs: D2-Like Receptors." In The Dopamine Receptors. Humana Press, 2009. http://dx.doi.org/10.1007/978-1-60327-333-6_5.

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Neve, Kim A. "Dopamine Receptors." In Dopamine and Glutamate in Psychiatric Disorders. Humana Press, 2005. http://dx.doi.org/10.1007/978-1-59259-852-6_1.

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Fuxe, Kjell, Daniel Marcellino, Diego Guidolin, Amina Woods, and Luigi Agnati. "Dopamine Receptor Oligomerization." In The Dopamine Receptors. Humana Press, 2009. http://dx.doi.org/10.1007/978-1-60327-333-6_10.

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Seeman, Philip. "Historical Overview: Introduction to the Dopamine Receptors." In The Dopamine Receptors. Humana Press, 2009. http://dx.doi.org/10.1007/978-1-60327-333-6_1.

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Cepeda, Carlos, Véronique M. André, Emily L. Jocoy, and Michael S. Levine. "Dopamine Receptor Modulation of Glutamatergic Neurotransmission." In The Dopamine Receptors. Humana Press, 2009. http://dx.doi.org/10.1007/978-1-60327-333-6_11.

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Tirotta, Emanuele, Claudia De Mei, Chisato Iitaka, Maria Ramos, Dawn Holmes, and Emiliana Borrelli. "Unraveling the Role of Dopamine Receptors In Vivo: Lessons from Knockout Mice." In The Dopamine Receptors. Humana Press, 2009. http://dx.doi.org/10.1007/978-1-60327-333-6_12.

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O’Sullivan, Gerard J., Colm O’Tuathaigh, Katsunori Tomiyama, Noriaki Koshikawa, and John L. Waddington. "Dopamine Receptors and Behavior: From Psychopharmacology to Mutant Models." In The Dopamine Receptors. Humana Press, 2009. http://dx.doi.org/10.1007/978-1-60327-333-6_13.

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Seamans, Jeremy K., and Trevor W. Robbins. "Dopamine Modulation of the Prefrontal Cortex and Cognitive Function." In The Dopamine Receptors. Humana Press, 2009. http://dx.doi.org/10.1007/978-1-60327-333-6_14.

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Abi-Dargham, Anissa, and Marc Laruelle. "In Vivo Imaging of Dopamine Receptors." In The Dopamine Receptors. Humana Press, 2009. http://dx.doi.org/10.1007/978-1-60327-333-6_15.

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Conference papers on the topic "Dopamine receptors"

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Wang, Xiaoxin, Ke Li, Jiali Cheng, Yanhang Zhang, and Lijuan Hou. "Research Progress of Dopamine Receptors and Motor Control." In 2017 2nd International Symposium on Advances in Electrical, Electronics and Computer Engineering (ISAEECE 2017). Atlantis Press, 2017. http://dx.doi.org/10.2991/isaeece-17.2017.2.

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Trzaskowski, Bartosz, and Kinga Ostrowska. "Targeting depression via computational approaches to design new coumarinbased serotonin receptor antagonists/agonists and develop reliable models of G protein-coupled receptors." In 2nd International Conference on Chemo and BioInformatics. Institute for Information Technologies, University of Kragujevac, 2023. http://dx.doi.org/10.46793/iccbi23.010t.

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It has been over 60 years since the pharmacological mechanisms of action of antidepressant drugs and the role of serotonin, norepinephrine, and dopamine in depression and other neurological disorders have been established. Since then, a very large number of chemical compounds targeting among others, serotonin and dopamine receptors have been developed. Here we present the most recent approaches to design and develop a new class of coumarinbased candidates for antidepressants with the help of computational studies
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ARDEN, John. "SEARCHING FOR HAPPINESS IN THE WRONG PLACES." In Proceedings of The Third International Scientific Conference “Happiness and Contemporary Society”. SPOLOM, 2022. http://dx.doi.org/10.31108/7.2022.2.

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Addiction mechanisms are described from neuropsychological perspective and explicated in terms of false happiness seeking. The reward pathways in the brain are analyzed. Methods and techniques for sustainable happiness are suggested and argued. Key words: happiness, pleasure, addiction, dopamine receptors, brain networks.
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Mahdavi, Ali, Mina Mirjalili, Fariba Bahrami, and Mahyar Janahmadi. "Hypofunction of NMDA receptors due to the hyperactivation of dopamine receptors in the hippocampal synapses of schizophrenia based mathematical model." In 2015 22nd Iranian Conference on Biomedical Engineering (ICBME). IEEE, 2015. http://dx.doi.org/10.1109/icbme.2015.7404134.

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Kline, Christina Leah B., Amriti Lulla, Jessica Wagner, et al. "Abstract 3213: Antagonism of D2-like dopamine receptors plays a role in Onc201’s anticancer effects." In Proceedings: AACR Annual Meeting 2017; April 1-5, 2017; Washington, DC. American Association for Cancer Research, 2017. http://dx.doi.org/10.1158/1538-7445.am2017-3213.

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Nichiporenko, A. A., G. A. Balakireva, D. V. Podrezova, and E. N. Turalina. "Age aspects of the effect of blocking D2/D3 dopamine receptors with sulpiride on the behavioral parameters." In II Международная конференция, посвящеенная 100- летию И.А. Држевецкой. СКФУ, 2022. http://dx.doi.org/10.38006/9612-62-6.2022.239.243.

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Rashid, Habiba. "Interplay Between Muscarinic And Dopamine Receptors Activity On Retrieving Hippocampal Dependent Memories In Male And Female Mice." In International Conference on Biological Research and Applied Science. Jinnah University for Women, Karachi,Pakistan, 2022. http://dx.doi.org/10.37962/ibras/2022/46-48.

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Budiono, Budiono, Sumirah Budi Pertami, Siti Nur Arifah, and Sri Rahayu Lestari. "Molecular docking analysis of Polyscias scutellaria active compounds as inhibitor of dopamine D2 receptors to increase prolactin secretion." In INTERNATIONAL CONFERENCE ON LIFE SCIENCES AND TECHNOLOGY (ICoLiST 2020). AIP Publishing, 2021. http://dx.doi.org/10.1063/5.0052655.

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Pavletić, Pegi. "Development of a novel class of brain penetrant ligands endowed with high affinity and selectivity for dopamine D4 receptors." In 6th International Electronic Conference on Medicinal Chemistry. MDPI, 2020. http://dx.doi.org/10.3390/ecmc2020-07926.

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Sheikhpour, Mojhgan, Ghasem Ahangari, Majid Sadeghizadeh, and Kian khodadad. "Abstract 5316: Significant changes in D2-like dopamine gene receptors expression associated with non- small -cell lung cancer: A case control study." In Proceedings: AACR 104th Annual Meeting 2013; Apr 6-10, 2013; Washington, DC. American Association for Cancer Research, 2013. http://dx.doi.org/10.1158/1538-7445.am2013-5316.

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Reports on the topic "Dopamine receptors"

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Yan, Qingshan. Ethanol and Mesolimbic Serotonin/Dopamine Interactions Via 5-HT1B Receptors. Defense Technical Information Center, 2006. http://dx.doi.org/10.21236/ada455523.

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Yan, Qingshan. Ethanol and Mesolimbic Serotonin/Dopamine Interactions via 5HT-1B Receptors. Defense Technical Information Center, 2003. http://dx.doi.org/10.21236/ada416991.

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Yan, Qingshan. Ethanol and Mesolimbic Serotonin/Dopamine Interactions via 5-HT-1B Receptors. Defense Technical Information Center, 2005. http://dx.doi.org/10.21236/ada443060.

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Dr. Jogeshwar Mukherjee. Development of dopamine receptor radiopharmaceuticals for the study of neurological and psychiatric disorders. Office of Scientific and Technical Information (OSTI), 2009. http://dx.doi.org/10.2172/944919.

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Mukherjee, J. Development of dopamine receptor radiopharmaceuticals for the study of neurological and psychiatric disorders. Progress report 1994--1997. Office of Scientific and Technical Information (OSTI), 1999. http://dx.doi.org/10.2172/764610.

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99mTc SPECT-CT, Consensus QIBA Profile. Chair Yuni Dewaraja and Robert Miyaoka. Radiological Society of North America (RSNA)/Quantitative Imaging Biomarkers Alliance (QIBA), 2019. https://doi.org/10.1148/qiba/20191021.

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The quantification of 99mTc labeled biomarkers can add unique value in many different settings, ranging from clinical trials of investigation new drugs to the treatment of individual patients with marketed therapeutics. For example, goals of precision medicine include using companion radiopharmaceutical diagnostics as just-in-time, predictive biomarkers for selecting patients to receive targeted treatments, customizing doses of internally administered radiotherapeutics, and assessing responses to treatment. This Profile describes quantitative outcome measures that represent proxies of target c
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