Academic literature on the topic 'Engraftment'

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Journal articles on the topic "Engraftment"

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Unal, Ali, Leylagül Kaynar, Esra Yıldızhan, et al. "The Comparison of Melphalan Administration on Day 3 with Administration on Day 1 on Neutrophil and Platelet Engraftment in Multiple Myeloma Patients Undergoing Autologous Stem Cell Transplantation." Blood 132, Supplement 1 (2018): 5767. http://dx.doi.org/10.1182/blood-2018-99-115353.

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Abstract Objective: High dose chemotherapy followed by ASCT is the most important step of MM treatment. Melphalan, an alkylating agent, is the most preferable drug for conditioning regimens and dosage and timing is important with regards to side effects or engraftment timing. Engraftment time is determinative on infections and hospitalization duration. Methods: We compared the neutrophil and thrombocyte engraftments retrospectively in patients with multiple myeloma who received melphalan 200 mg/m2 single dose on day -3 and day -1 as conditioning regimen. There were 29 patient receiving melphal
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Unal, A., L. Kaynar, N. Keni, et al. "The Comparison of Melphalan Administration on Day −3 With Administration on Day −1 on Neutrophil and Platelet Engraftment in Multiple Myeloma Patients Undergoing Autologous Stem Cell Transplantation." Journal of Global Oncology 4, Supplement 2 (2018): 218s. http://dx.doi.org/10.1200/jgo.18.88300.

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Background: High dose chemotherapy followed by ASCT is the most important step of MM treatment. Melphalan, an alkylating agent, is the most preferable drug for conditioning regimens and dosage and timing is important with regard to side effects or engraftment timing. Engraftment time is determinative on infections and hospitalization duration. Aim: To compare of the neutrophil and thrombocyte engraftment time in patients with multiple myeloma who received melphalan 200 mg/m2 single dose on day −3 and day −1 as conditioning regimen. Methods: We compared the neutrophil and thrombocyte engraftmen
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Unal, A., A. Birekul, L. Kaynar, B. Eser, and M. Cetin. "Successful Treatment With Granulocyte Transfusion and Early Neutrophil Engraftment in Allogeneic Transplant Patients With Febrile Neutropenia: Does Granulocyte Transfusion Effect on Neutrophil Engraftment?" Journal of Global Oncology 4, Supplement 2 (2018): 225s. http://dx.doi.org/10.1200/jgo.18.91100.

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Background: Febrile neutropenia is very severe and urgent early complication after bone marrow transplantation before engraftment. Infection delays engraftments in these periods. Aim: In this study we evaluated the effect and outcome of granulocyte transfusion on febrile neutropenia and neutrophil engraftment in patients receiving allogeneic transplantation. The reasons for the use of the granulocyte transfusion were prolonged febrile neutropenia episode. Methods: Between 2015-2017, 16 patients receiving allogeneic bone marrow transplantation (BMT) were treated with granulocyte transfusion at
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Korovin, Sergii, Vasyl Ostafiichuk, Serhii Diedkov, and Mariia Kukushkina. "Experience of Vacuum-Assisted Closure in the Surgical Treatment of Malignant Skin Tumors after Skin Grafting." Open Access Macedonian Journal of Medical Sciences 10, B (2022): 2520–22. http://dx.doi.org/10.3889/oamjms.2022.11046.

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BACKGROUND: Skin grafts may be used to reconstruct large skin defects after the excision of malignant skin tumors. Vacuum-assisted closure (VAC) leads closer approximation of the free flap. AIM: The objective of this study was to estimate the engraftment of grafts using VAC and explore factors influencing this process. MATERIALS AND METHODS: This study included 31 patients with skin cancers after a wide tumor excision. The wound defects were closed using a split-thickness skin graft and the VAC dressing. RESULTS: Complete and partial engraftment was observed in 17 (54.8 %) and 14 (45.2%) cases
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Zheng, Nancy (Xiaoqing), Guoxiang Yang, James Keck, and Li-Chin Yao. "Abstract 7235: New mouse strain NSG-SGM3xIL15xDKO is better for PBMC engraftment in Raji-bearing mice of minor immune subsets compared to NSG-MHC I/II DKO mouse." Cancer Research 85, no. 8_Supplement_1 (2025): 7235. https://doi.org/10.1158/1538-7445.am2025-7235.

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Abstract Introduction: PBMC-humanized MHC I/II double knock-out (#025216, DKO) strain has shown strong T cell engraftment with minimal acute GVHD. We recently have developed two new mouse strains, NSG-SGM3xIL15xDKO (SDKO) and NSG-FLT3LxDKO (FDKO), and their engraftment comparison data will be presented in the same meeting. Here we aimed to investigate the engraftment of various immune cell types in SDKO and FDKO mice in the presence of tumor stimulation. Methods: We assessed PBMC engraftment levels and immune subtypes in irradiated SDKO, FDKO, and DKO implanted with lymphoma (Raji-luc and Nalm
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İTMEÇ, Yeşim, Serhat ÇELİK, and Ali ÜNAL. "The effect of granulocyte transfusion on engraftment in patients with allogeneic hematopoietic stem cell transplantation." Journal of Health Sciences and Medicine 6, no. 3 (2023): 674–79. http://dx.doi.org/10.32322/jhsm.1275159.

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Aim: Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is still one of the most effective treatments for many hematological malignancies. However, especially infections and neutropenic fever increase mortality during the engraftment development process after allo-HSCT. This study investigated the effect and safety profile of granulocyte transfusion (GT) on engraftment in patients with neutropenic fever after allo-HSCT.
 Material and Method: We investigated 32 patients with hematological malignancies who had neutropenic fever following allo-HSCT between June 2018 and February
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Marzorati, Simona, Raffaella Melzi, Antonio Citro, et al. "Engraftment Versus Immunosuppression." Transplantation 97, no. 10 (2014): 1019–26. http://dx.doi.org/10.1097/tp.0000000000000104.

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Summers, E., M. A. Frey, and J. Kurtzberg. "414: Engraftment syndrome." Biology of Blood and Marrow Transplantation 13, no. 2 (2007): 148. http://dx.doi.org/10.1016/j.bbmt.2007.01.044.

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Kawashima, Naomi, Satoshi Nishiwaki, Seitaro Terakura, et al. "Impact of Macrophage Activation on Delayed Engraftment Following Allogeneic Hematopoietic Stem Cell Transplantation: Mac Ratio, a New Predictive Index." Blood 122, no. 21 (2013): 4527. http://dx.doi.org/10.1182/blood.v122.21.4527.4527.

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Introduction Delayed engraftment and subsequent engraftment failure cause fatal complications including severe infection and lead to poor prognosis after allogeneic hematopoietic stem cell transplantation (allo-SCT). We have previously reported that hemophagocytic syndrome (HPS) induced by uncontrolled macrophage activation in bone marrow had high mortality due to engraftment failure (BMT.2012;47:387–394). Macrophages are phagocytic cells with abilities of phagocytosis, antigen-presenting, and secretion of cytokines. Although phagocytosis reflects only a part of their activation, their morphol
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Zheng, Nancy (Xiaoqing), Kevin Tsai, Guoxiang Yang, et al. "Abstract 7230: New mouse strains NSG-SGM3xIL15xDKO and NSG- FLT3LxDKO are superior to NSG-MHC I/II DKO mice for humanization of peripheral blood mononuclear cells." Cancer Research 85, no. 8_Supplement_1 (2025): 7230. https://doi.org/10.1158/1538-7445.am2025-7230.

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Abstract Background: Peripheral blood mononuclear cells (PBMC)-humanized mice serve as important platforms to evaluate efficacy and toxicity. NSG-MHC I/II double-knock out (DKO) mice have been widely used due to being a humanized T cell model with delayed graft-versus-host disease. However, achieving at least 5% engraftment within a week requires 10-15e6 PBMCs per mouse with irradiation, which accelerates PBMCs to engraft compared to non-irradiated mice. Additionally, engraftment of certain cell populations, such as natural killer (NK) cells and monocytes from PBMC has been challenging in the
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Dissertations / Theses on the topic "Engraftment"

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Pepperell, Emma E. "The regulation of stem cell engraftment." Thesis, University of Oxford, 2013. http://ora.ox.ac.uk/objects/uuid:873a14b9-6c7b-4643-bb34-4e1679d4f734.

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The engraftment of haemopoietic stem/progenitor cells (HSPCs) from umbilical cord blood (UCB) into adult recipients, although advantageous in terms of sourcing units, the decreased need to match donor and recipient and reduced risk of graft versus host disease (GvHD), is delayed compared to grafts using HSPCs from mobilised peripheral blood (MPB) or bone marrow (BM). One reason for this is the limited number of HSPCs (CD34+/CD133+ cells) in a unit of UCB compared to MPB or BM. The CXCR4-CXCL12 axis is widely recognised as a key player in the bone marrow homing, retention, and engraftment of HS
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Escobedo, Cousin M. H. "Ancillary cell help in haematopoietic cord blood engraftment." Thesis, University College London (University of London), 2014. http://discovery.ucl.ac.uk/1424406/.

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Cord blood (CB) has served as a source of haematopoietic stem cells (HSC) to treat haematological diseases for the last two decades. Low incidence and severity of graft-versus-host disease, and a robust graft-versus-leukaemia effect are some of CB advantages as a source for HSC. However, its main disadvantages are a limited number of HSC per unit and delayed immune reconstitution and infections after CB transplantation (CBT). In order to improve engraftment and immune reconstitution after CBT different approaches have been explored like HSC expansion, double CB transplantation, CBT plus third
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Chu, Jennifer. "Enhanced engraftment of genetically modified bone marrow stromal cells." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2001. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp04/MQ58851.pdf.

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Lee, I.-Hui. "On CNS injury and olfactory ensheathing cell engraftment strategies /." Stockholm, 2005. http://diss.kib.ki.se/2005/91-7140-551-8/.

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He, Zhong. "Modifying xenogeneic immune recognition and engraftment by genetic engineering /." Stockholm, 2005. http://diss.kib.ki.se/2005/91-7140-353-1/.

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Tsaknakis, Grigorios. "Molecular mechanisms of stem cell migration, homing and engraftment." Thesis, University of Oxford, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.497129.

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Takemoto, Naohiro. "Protective Strategies for Enhancing Engraftment of Insulin Releasing Cells." 京都大学 (Kyoto University), 2014. http://hdl.handle.net/2433/188602.

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Colletti, Evan. "Human mesenchymal stem cell engraftment in the chimeric sheep model." abstract and full text PDF (free order & download UNR users only), 2006. http://0-gateway.proquest.com.innopac.library.unr.edu/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqdiss&rft_dat=xri:pqdiss:3209960.

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Ahmed, Forhad. "Homing and engraftment of CD34+ cells in the NOD/SCID model." Thesis, University College London (University of London), 2005. http://discovery.ucl.ac.uk/1445284/.

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The reduced engraftment potential of haemopoietic stem/progenitor cells after exposure to cytokines may be related to the impaired homing ability of actively cycling cells. I tested this hypothesis by quantifying the short-term homing of human adult CD34+ cells in NOD/SCID animals. I have demonstrated in adult CD34+ cells that cytokine exposure ex-vivo leads to a loss of engraftment ability in vivo which occurs rapidly and which is associated with a striking alteration in the tissue distribution of homed cells. Loss of homing to the BM and to a lesser extent, the spleen, coincides with increas
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Liu, Wei. "Rational targeting of Cdc42 in hematopoietic stem cell mobilization and engraftment." University of Cincinnati / OhioLINK, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1303845649.

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Books on the topic "Engraftment"

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Chu, Jennifer. Enhanced engraftment of genetically modified bone marrow stromal cells. National Library of Canada, 2001.

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Grossi, Danny. Long-term engraftment of bone marrow stromal cells in unconditioned murine recipients. National Library of Canada, 1996.

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Saunders, Melanie Jane. DNA studies of engraftment and clonality after bone marrow transplantation for haematological malignancies. University of Manchester, 1993.

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Liu, Tianbiao. IGF-1 transfection enhances cardiac smooth muscle cell engraftment. 2004.

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Menasché, Philippe. Stem Cell Therapy Post-AMI. Oxford University Press, 2011. http://dx.doi.org/10.1093/med/9780199544769.003.0010.

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• Experimental studies suggest that bone marrow-derived stem cells can improve function of infarcted myocardium• This benefit seems to involve paracrine signalling and limitation of left ventricular remodelling rather than true regeneration of cardiomyocytes from donor cells• These experimental findings have been translated in the clinical setting into significant, although moderate, improvements in cardiac function and LV remodelling but the extent to which these benefits impact on event-free long term survival remains to be determined• Optimisation of this therapeutic strategy will require a
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Book chapters on the topic "Engraftment"

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Murray, Sara. "Engraftment." In Blood and Marrow Transplant Handbook. Springer New York, 2010. http://dx.doi.org/10.1007/978-1-4419-7506-5_12.

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Murray, Sara. "Engraftment." In Blood and Marrow Transplant Handbook. Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-13832-9_14.

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Runaas, Lyndsey, Parameswaran Hari, and Saurabh Chhabra. "Engraftment." In Blood and Marrow Transplant Handbook. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-53626-8_14.

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Spitzer, Thomas R. "Engraftment Syndrome and Peri-engraftment Respiratory Distress." In Pulmonary and Critical Care Considerations of Hematopoietic Stem Cell Transplantation. Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-28797-8_15.

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Brown, Valerie I. "Engraftment and Chimerism." In Hematopoietic Stem Cell Transplantation for the Pediatric Hematologist/Oncologist. Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-63146-2_10.

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Rennert, Hanna, Debra G. B. Leonard, and Tsiporah Shore. "Bone Marrow Engraftment Analysis." In Diagnostic Molecular Pathology in Practice. Springer Berlin Heidelberg, 2011. http://dx.doi.org/10.1007/978-3-642-19677-5_19.

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Jethava, Yogesh, Madan Jagasia, Mohamed Mohty, and Bipin N. Savani. "Engraftment and graft failure." In Clinical Manual of Blood and Bone Marrow Transplantation. John Wiley & Sons, Ltd, 2017. http://dx.doi.org/10.1002/9781119095491.ch34.

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Sullivan, Harold C., Deanna C. Fang, and Jennifer Q. Zhang. "Bone Marrow Engraftment Analysis." In Practical Oncologic Molecular Pathology. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-73227-1_20.

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Hutt, Daphna. "Engraftment, Graft Failure, and Rejection." In The European Blood and Marrow Transplantation Textbook for Nurses. Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-50026-3_13.

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Hutt, Daphna. "Engraftment, Graft Failure, and Rejection." In The European Blood and Marrow Transplantation Textbook for Nurses. Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-23394-4_14.

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AbstractEngraftment following HSCT is an essential goal for sustained long-term and effective hematopoiesis. It is the most important criteria for a better overall survival. However, stem cell engraftment may be accompanied with a clinical condition known as engraftment syndrome (ES) that could have a devastating outcome. Nurses caring for HSCT recipients must be aware of ES symptoms in order to intervene quickly and appropriately. Conversely, graft failure (GF) is a major complication and is associated with a dismal prognosis. It is classically divided into primary or secondary graft failure.
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Conference papers on the topic "Engraftment"

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Cassino, Theresa R., Masaho Okada, Lauren M. Drowley, Joseph Feduska, Johnny Huard, and Philip R. LeDuc. "Using Mechanical Environment to Enhance Stem Cell Transplantation in Muscle Regeneration." In ASME 2007 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2007. http://dx.doi.org/10.1115/sbc2007-176545.

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Muscle-derived stem cell (MDSC) transplantation has shown potential as a therapy for cardiac and skeletal muscle dysfunction in diseases such as Duchenne muscular dystrophy (DMD). In this study we explore mechanical environment and its effects on MDSCs engraftment into cardiac and skeletal muscle in mdx mice and neoangiogenesis within the engraftment area. We first looked at transplantation of the same number of MDSCs into the heart and gastrocnemius (GN) muscle of dystrophic mice and the resulting dystrophin expression. We then explored neoangiogenesis within the engraftments through quantifi
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Lama, Vibha N., Linda Badri, Natalie Walker, et al. "Epithelial Interactions And Local Engraftment Of Lung-Resident Mesenchymal Stem Cells." In American Thoracic Society 2011 International Conference, May 13-18, 2011 • Denver Colorado. American Thoracic Society, 2011. http://dx.doi.org/10.1164/ajrccm-conference.2011.183.1_meetingabstracts.a3766.

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Wieruszewski, P. M., H. A. Personett, S. G. Peters, et al. "Characteristics of Corticosteroid Use in the Peri-Engraftment Respiratory Distress Syndrome." In American Thoracic Society 2019 International Conference, May 17-22, 2019 - Dallas, TX. American Thoracic Society, 2019. http://dx.doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a3451.

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Moore, John C., Qin Tang, Nora Torres Yordan, et al. "Abstract 4177: Dynamic visualization of cancer cell engraftment into immune compromised zebrafish." In Proceedings: AACR 107th Annual Meeting 2016; April 16-20, 2016; New Orleans, LA. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/1538-7445.am2016-4177.

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Dias, Carolina C., Amanda Nogueira-Pedro, Edgar J. Paredes-Gamero, and Antonio Miranda. "Leptin Fragment Increase Hematopoietic Stem Cell Population and Improve Its Engraftment Ability." In The 24th American Peptide Symposium. Prompt Scientific Publishing, 2015. http://dx.doi.org/10.17952/24aps.2015.086.

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Kaur, Pali, Victoria Sachs, Amanda L. Christie, David M. Weinstock, and James G. Keck. "Abstract 700: Characterization of new AML PDX models: Engraftment kinetics and mutational profile." In Proceedings: AACR Annual Meeting 2018; April 14-18, 2018; Chicago, IL. American Association for Cancer Research, 2018. http://dx.doi.org/10.1158/1538-7445.am2018-700.

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Abdulai, Raolat M., and Bekele Afessa. "Peri-Engraftment Respiratory Distress Syndrome (Perds) In Hematopoietic Stem Cell Transplant (HSCT) Recipients." In American Thoracic Society 2011 International Conference, May 13-18, 2011 • Denver Colorado. American Thoracic Society, 2011. http://dx.doi.org/10.1164/ajrccm-conference.2011.183.1_meetingabstracts.a1146.

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Vaisitti, Tiziana, Valentina Audrito, Sara Serra, et al. "Abstract 1348: CD38 regulates homing and engraftment in a mouse model of CLL." In Proceedings: AACR 103rd Annual Meeting 2012‐‐ Mar 31‐Apr 4, 2012; Chicago, IL. American Association for Cancer Research, 2012. http://dx.doi.org/10.1158/1538-7445.am2012-1348.

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Herriges, M., B. R. Thapa, J. Lindstrom-Vautrin, F. Wang, C. Villacorta-Martin, and D. N. Kotton. "Durable Alveolar Engraftment of PSC-derived Lung Tip-like Cells Into Immunocompetent Mice." In American Thoracic Society 2023 International Conference, May 19-24, 2023 - Washington, DC. American Thoracic Society, 2023. http://dx.doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a4701.

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Maughan, Elizabeth F., Chun Hang Lau, Lei Wu, et al. "Late Breaking Abstract - Engraftment of autologous airway epithelial cells in the rabbit trachea." In ERS Congress 2024 abstracts. European Respiratory Society, 2024. http://dx.doi.org/10.1183/13993003.congress-2024.oa4542.

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Reports on the topic "Engraftment"

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Chiu, Chia-Yu, and Patrick Ching. Intravenous pentamidine for Pneumocystis jirovecii pneumonia prophylaxis in immunocompromised patients without human immunodeficiency virus: a systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2022. http://dx.doi.org/10.37766/inplasy2022.12.0072.

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Review question / Objective: Breakthrough PJP rate and adverse reactions in HIV-uninfected immunocompromised patients who received intravenous pentamidine. Rationale: Trimethoprim-sulfamethoxazole (TMP-SMX) is a first-line Pneumocystis jirovecii pneumonia (PJP) prophylaxis agent, but intravenous pentamidine (IVP) every 4 weeks (Q4W) is commonly used in human immunodeficiency virus (HIV)-uninfected immunocompromised hosts because IVP is not associated with cytopenia and delayed engraftment. Breakthrough PJP rate on TMP-SMX prophylaxis, incidence of adverse reactions, and adverse events requirin
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