Academic literature on the topic 'Epidermal hair'

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Journal articles on the topic "Epidermal hair"

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Nakrieko, Kerry-Ann, Alena Rudkouskaya, Timothy S. Irvine, Sudhir J. A. D'souza, and Lina Dagnino. "Targeted inactivation of integrin-linked kinase in hair follicle stem cells reveals an important modulatory role in skin repair after injury." Molecular Biology of the Cell 22, no. 14 (2011): 2532–40. http://dx.doi.org/10.1091/mbc.e11-01-0035.

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Integrin-linked kinase (ILK) is key for normal epidermal morphogenesis, but little is known about its role in hair follicle stem cells and epidermal regeneration. Hair follicle stem cells are important contributors to newly formed epidermis following injury. We inactivated the Ilk gene in the keratin 15–expressing stem cell population of the mouse hair follicle bulge. Loss of ILK expression in these cells resulted in impaired cutaneous wound healing, with substantially decreased wound closure rates. ILK-deficient stem cells produced very few descendants that moved toward the epidermal surface
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Chermnykh, Elina S., Elena V. Alpeeva, and Ekaterina A. Vorotelyak. "Transglutaminase 3: The Involvement in Epithelial Differentiation and Cancer." Cells 9, no. 9 (2020): 1996. http://dx.doi.org/10.3390/cells9091996.

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Transglutaminases (TGMs) contribute to the formation of rigid, insoluble macromolecular complexes, which are essential for the epidermis and hair follicles to perform protective and barrier functions against the environment. During differentiation, epidermal keratinocytes undergo structural alterations being transformed into cornified cells, which constitute a highly tough outermost layer of the epidermis, the stratum corneum. Similar processes occur during the hardening of the hair follicle and the hair shaft, which is provided by the enzymatic cross-linking of the structural proteins and ker
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Lorenz, Katrin, Carsten Grashoff, Robert Torka, et al. "Integrin-linked kinase is required for epidermal and hair follicle morphogenesis." Journal of Cell Biology 177, no. 3 (2007): 501–13. http://dx.doi.org/10.1083/jcb.200608125.

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Integrin-linked kinase (ILK) links integrins to the actin cytoskeleton and is believed to phosphorylate several target proteins. We report that a keratinocyte-restricted deletion of the ILK gene leads to epidermal defects and hair loss. ILK-deficient epidermal keratinocytes exhibited a pronounced integrin-mediated adhesion defect leading to epidermal detachment and blister formation, disruption of the epidermal–dermal basement membrane, and the translocation of proliferating, integrin-expressing keratinocytes to suprabasal epidermal cell layers. The mutant hair follicles were capable of produc
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Li, M., H. Chiba, X. Warot, et al. "RXR-alpha ablation in skin keratinocytes results in alopecia and epidermal alterations." Development 128, no. 5 (2001): 675–88. http://dx.doi.org/10.1242/dev.128.5.675.

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RXR-alpha is the most abundant of the three retinoid X receptors (RXRs) in the epidermis. In this study, we have used Cre-mediated recombination to selectively disrupt the mouse gene for RXR-alpha in epidermal and hair follicle keratinocytes. We show that RXR-alpha is apparently dispensable for prenatal epidermal development, while it is involved in postnatal skin maturation. After the first hair pelage, mutant mice develop a progressive alopecia, histologically characterised by the destruction of hair follicle architecture and the formation of utriculi and dermal cysts in adult mice. Our resu
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Reynolds, A. J., and C. A. Jahoda. "Hair follicle stem cells? A distinct germinative epidermal cell population is activated in vitro by the presence of hair dermal papilla cells." Journal of Cell Science 99, no. 2 (1991): 373–85. http://dx.doi.org/10.1242/jcs.99.2.373.

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Germinative epidermal cells in the lower end bulb region of anagen hair follicles are highly active, and give rise to hair fibres through rapid proliferation and complex differentiation. They have often been termed hair follicle stem cells, but owing to difficulties in isolation and identification their properties have previously only been clearly documented in vivo. We aimed to isolate and culture germinative cells in vitro, and used microdissection methods to dissect a small but identifiable group of cells from complete follicles. Transmission electron microscopy confirmed that the isolated
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Mokry, Jaroslav, and Rishikaysh Pisal. "Development and Maintenance of Epidermal Stem Cells in Skin Adnexa." International Journal of Molecular Sciences 21, no. 24 (2020): 9736. http://dx.doi.org/10.3390/ijms21249736.

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The skin surface is modified by numerous appendages. These structures arise from epithelial stem cells (SCs) through the induction of epidermal placodes as a result of local signalling interplay with mesenchymal cells based on the Wnt–(Dkk4)–Eda–Shh cascade. Slight modifications of the cascade, with the participation of antagonistic signalling, decide whether multipotent epidermal SCs develop in interfollicular epidermis, scales, hair/feather follicles, nails or skin glands. This review describes the roles of epidermal SCs in the development of skin adnexa and interfollicular epidermis, as wel
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Kwochka, Kenneth W., and Adriana M. Rademakers. "Cell proliferation kinetics of epidermis, hair follicles, and sebaceous glands of Cocker Spaniels with idiopathic seborrhea." American Journal of Veterinary Research 50, no. 11 (1989): 1918–22. https://doi.org/10.2460/ajvr.1989.50.11.1918.

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SUMMARY Cell proliferation kinetic values were established for the epidermis, hair follicle epithelium, and sebaceous glands of 8 Cocker Spaniels with primary idiopathic seborrhea. Values were established by intradermal pulse labeling injections of tritiated thymidine followed by cutaneous biopsy and autoradiography. The epidermal basal cell-labeling index was 4.96 ± 0.97%, and the epidermal nucleated cell-labeling index was 3.33 ± 0.71%. Calculated epidermal cell renewal time for the viable layers of the epidermis was 7.85 ± 1.80 days. The hair follicle infundibulum basal cell-labeling index
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DasGupta, Ramanuj, Horace Rhee, and Elaine Fuchs. "A developmental conundrum." Journal of Cell Biology 158, no. 2 (2002): 331–44. http://dx.doi.org/10.1083/jcb.200204134.

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Wnt signaling orchestrates morphogenetic processes in which changes in gene expression are associated with dramatic changes in cell organization within developing tissue/organss. Upon signaling, excess β-catenin not utilized at cell–cell junctions becomes stabilized, where it can provide the transcriptional activating domain for Lef/Tcf DNA binding proteins. In skin epithelium, forced stabilization of β-catenin in epidermis promotes hair follicle morphogenesis, whereas conditional removal of β-catenin in hair progenitor cells specifies an epidermal fate. We now report that a single protein, a
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Li, Yafan, Deric L. Wheeler, Wade Alters, Luksana Chaiswing, Ajit K. Verma та Terry D. Oberley. "Early Epidermal Destruction with Subsequent Epidermal Hyperplasia Is a Unique Feature of the Papilloma-Independent Squamous Cell Carcinoma Phenotype in PKCε Overexpressing Transgenic Mice". Toxicologic Pathology 33, № 6 (2005): 684–94. http://dx.doi.org/10.1080/01926230500323441.

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Protein kinase C epsilon (PKCε) overexpressing transgenic (PKCεTg) mice develop papilloma-independent squamous cell carcinomas (SCC) elicited by 7,12-dimethylbenz[a]anthracene (DMBA) tumor initiation and 12- O-tetradecanoylphorbol-13-acetate (TPA) tumor promotion. We examined whether epidermal cell turnover kinetics was altered during the development of SCC in PKCε Tg mice. Dorsal skin samples were fixed for histological examination. A single application of TPA resulted in extensive infiltration of polymorphonuclear neutrophils (PMNs) into the epidermis at 24 h after TPA treatment in PKCε Tg m
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Seechurn, P., S. A. Burchill та A. J. Thody. "Effect of α-melanocyte-stimulating hormone on tyrosinase activity in hair follicular and epidermal melanocytes of the mouse". Journal of Endocrinology 119, № 3 (1988): 517–22. http://dx.doi.org/10.1677/joe.0.1190517.

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ABSTRACT In this study, the effect of α-MSH on tyrosinase activity was compared in epidermal and hair follicular melanocytes of mice. It had no effect on epidermal tyrosinase activity in dorsal skin from neonatal non-agouti black mice (C57BL/6J) in both in-vivo and in-vitro experiments. Theophylline and 8-bromocyclic (c)AMP were similarly without effect in in-vitro experiments. In-vivo administration of α-MSH and theophylline for 7 days was also without effect on epidermal tyrosinase activity in ear skin of adult non-agouti mice, and the same was true for α-MSH in wild-type agouti mice. Activa
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Dissertations / Theses on the topic "Epidermal hair"

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Whitehouse, Claire Jenna. "Hair follicle germinative epidermal cells : a molecular study." Thesis, Durham University, 1999. http://etheses.dur.ac.uk/4292/.

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At the base of the hair follicle epidermal matrix is a population of germinative epidermal (GE) cells that is in close communication with the dermal papilla. These GE cells are at the core of activities that comprise the fundamental processes of cell signalling and differentiation in the hair follicle. Since it is in the germinative region that the signals that produce hair are being received and transcribed, identification of genes expressed in the GE cells will be important for our understanding of hair growth control and the molecular mechanisms operating at the site of epidermal proliferat
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Asamaowei, Inemo E. "The Role of Polycomb Repressive Complex 2 in Epidermal Homeostasis and Hair Growth." Thesis, University of Bradford, 2017. http://hdl.handle.net/10454/16844.

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Polycomb repressive complex 2 (PRC2) catalyses the methylation of ‘Lys-27’ of histone H3, leading to transcriptional repression of target genes through its catalytic subunit Enhancer of zeste homolog 1/2 (EZH1/2). PRC2 functions as a critical regulator of stem cells in mouse embryonic and adult tissues. However, the role of PRC2 in human skin remains largely unknown. This study investigated the role of PRC2 in human epidermal homeostasis and hair growth. The expression of EZH2 was elevated in differentiating suprabasal layers of the human epidermis. Consistently, EZH1/2 expression and enzymat
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Foreman, Julia Louise. "Genetic and molecular analysis of root hair initiation and tip growth in Arabidopsis thaliana." Thesis, University of East Anglia, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.247111.

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Duhéron, Vincent. "Hair and epidermal renewal by the receptor activator of NF-kappaB." Strasbourg, 2009. http://www.theses.fr/2009STRA6154.

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Mak, King-lun Kingston. "A transgenic mouse model to study the role of epidermal growth factor (EGF) in hair and skin development." Click to view the E-thesis via HKUTO, 2002. http://sunzi.lib.hku.hk/hkuto/record/B42576787.

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Davidson, Bruce Paul, University of Western Sydney, and School of Biological Sciences. "Compound mutations in the mammalian EGFR signalling pathway affect epidermal development, growth and viability." THESIS_XXXX_SBS_Davidson_B.xml, 1997. http://handle.uws.edu.au:8081/1959.7/518.

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The widespread expression of polypeptide growth factors from the earliest stages of embryonic development through to mature issues in the adult organism suggests an involvement in a reiterated developmental process affecting the underlying cellular growth and differentiation of many tissues. The hair follicle has taken on increased significance with the observation that many genetic mutations in these peptide growth factor genes affect its development. The targeted disruption of genes encoding members of the EpidermalGrowth Factor (EGF) and Fibroblast Growth Factor (FGF) families in the mouse
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Yang, Chia-Ling. "Studies on the metabolism, ageing and response to epidermal growth factor of hair follicles." Thesis, University of Cambridge, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.620083.

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Barnbrook, Matthew David. "The gene(s) responsible for variation in epidermal hair (trichome) distribution amongst Antirrhinum species." Thesis, University of Edinburgh, 2017. http://hdl.handle.net/1842/29565.

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Trichomes are hair-like structures found on the surface of virtually all terrestrial plants (Yang et al., 2015). They are epidermal outgrowths that can occur on all of the aerial parts of a plant, varying markedly in size, shape, distribution, and in their ability to produce secondary metabolites. About 30% of all vascular plants carry the glandular trichomes capable of producing secondary metabolites (Glas et al., 2012). Trichomes are vitally important to plants as a defence mechanism, they are highly significant commercially, and they are of interest to plant biologists in that they serve as
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麥經綸 and King-lun Kingston Mak. "A transgenic mouse model to study the role of epidermal growthfactor (EGF) in hair and skin development." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2002. http://hub.hku.hk/bib/B42576787.

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Rahbar, Ramtin. "Claudin tight junctionwhat's your function? The role of Claudin 6 in epidermal and hair follicle differentiation." Thesis, University of Ottawa (Canada), 2004. http://hdl.handle.net/10393/26751.

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To elucidate the role of Claudin 6, a member of a new super family of TJ molecules, in the skin, we overexpressed it using the promoter for the differentiation marker, involucrin (Carrot et. al. 1993). Homozygous INV-Claudin 6 animals exhibit epidermal differentiation aberrations that result in incomplete formation of EPB and neonatal death (Turksen and Troy 2002). Heterozygote animals have milder EPB defects and survive to adulthood. All heterozygotes have pronounced abnormalities in their coat characterized by fuzzy hairs and a matte texture. In agreement with our hypothesis, the anagen phas
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Books on the topic "Epidermal hair"

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Zahn, Helmut. Reaktionen von Tensiden mit Wolle, Haar und Stratum Corneum. Deutsches Wollforschungsinstitut an der Technischen Hochschule Aachen, 1985.

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Sybert, Virginia P. Disorders of Epidermal Appendages. Oxford University Press, 2012. http://dx.doi.org/10.1093/med/9780195397666.003.0003.

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Hair – Alopecias – Loose Anagen Hair – Male Pattern Baldness – Marie Unna Syndrome – Hirsutism – Gingival Fibromatosis and Hypertrichosis – Hypertrichosis Lanuginosa Congenita – Leprechaunism – Localized Hypertrichosis – Polycystic Ovarian Disease – Hair Shaft Abnormalities, Isolated – Monilethrix – Pili Annulati – Pili Torti – Pili Trianguli Et Canaliculi – Trichorrhexis Invaginata – Trichorrhexis Nodosa – Woolly Hair – Hair Shaft Abnormalities, Syndromic – Menkes Disease – Trichodentoosseous Syndrome – Trichorhinophalangeal Syndrome – Trichothiodystrophy – Nails – Nail Disorders, Isolated –
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Sybert, Virginia P. Disorders of Epidermal Appendages. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190276478.003.0003.

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Chapter 3 starts by covering conditions of the hair, including Alopecias (Loose Anagen Hair, Male Pattern Baldness, and Marie Unna Syndrome), Hirsutism (Gingival Fibromatosis and Hypertrichosis, Hypertrichosis Lanuginosa Congenita, Leprechaunism, and Localized Hypertrichosis), and Hair Shaft Abnormalities (including Monilethrix, Pili Annulati, Pili Torti, Pili Trianguli Et Canaliculi, Trichorrhexis Invaginata, Trichorrhexis Nodosa, Woolly Hair, Menkes Disease, Trichodentoosseous Syndrome, Trichorhinophalangeal Syndrome, and Trichothiodystrophy). It then covers conditions of the nails, includin
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Berker, David de. Hair disorders. Edited by Patrick Davey and David Sprigings. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199568741.003.0253.

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This chapter discusses inflammatory scalp diseases and hair shedding (telogen effluvium and pattern hair loss). Inflammatory diseases of the scalp can affect all epidermal surfaces or focus upon the follicle, with relative sparing of the interfollicular skin. Eczema and psoriasis are examples of the former; other diseases, such as lichen planopilaris or discoid lupus erythematosus, are examples of the latter. Some follicular diseases, such as the family of diseases based on alopecia areata (alopecia areata (small areas of hair loss), alopecia totalis (whole scalp), and alopecia universalis (wh
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Jolly, Elaine, Andrew Fry, and Afzal Chaudhry, eds. Dermatology. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199230457.003.0006.

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Chapter 6 covers the basic science and clinical topics relating to dermatology which trainees are required to learn as part of their basic training and demonstrate in the MRCP. It covers eczema/dermatitis, psoriasis, blistering skin disorders, bacterial and viral infections of the skin, fungal infections and infestations, erythema multiforme, Stevens-Johnson syndrome/toxic epidermal necrolysis, erythema nodosum, drug eruptions, benign skin tumours, malignant skin tumours, the skin and systemic disease, cutaneous lupus erythematosus, systemic sclerosis (scleroderma), vasculitis, structure and f
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Kopan, Raphael. Keratins as markers of epithelial development: In vitro and in vivo study of epidermis and hair differentiation. 1989.

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Book chapters on the topic "Epidermal hair"

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Blumenberg, M., and M. Tomić-Canić. "Human epidermal keratinocyte: Keratinization processes." In Formation and Structure of Human Hair. Birkhäuser Basel, 1997. http://dx.doi.org/10.1007/978-3-0348-9223-0_1.

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Baker, Richard, and M. Julie Thornton. "Isolation of Epidermal and Hair Follicle Melanocytes." In Methods in Molecular Biology. Springer US, 2020. http://dx.doi.org/10.1007/978-1-0716-0648-3_3.

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Roop, Dennis R., Hisayoshi Nakazawa, Thomas Mehrel, et al. "Sequential Changes in Gene Expression during Epidermal Differentiation." In The Biology of Wool and Hair. Springer Netherlands, 1988. http://dx.doi.org/10.1007/978-94-011-9702-1_21.

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Yuspa, Stuart H., Henry Hennings, Robert W. Tucker, Susan Jaken, Anne E. Kilkenny, and Dennis R. Roop. "The Cultured Murine Epidermal Keratinocyte and Studies of Differentiation." In The Biology of Wool and Hair. Springer Netherlands, 1988. http://dx.doi.org/10.1007/978-94-011-9702-1_26.

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Badarinath, Krithika, Abhik Dutta, Akshay Hegde, Neha Pincha, Rupali Gund, and Colin Jamora. "Interactions Between Epidermal Keratinocytes, Dendritic Epidermal T-Cells, and Hair Follicle Stem Cells." In Skin Stem Cells. Springer New York, 2018. http://dx.doi.org/10.1007/7651_2018_155.

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Fuchs, Elaine, Andrea Stoler, Raphael Kopan, and Marjorie Rosenberg. "The Differential Expression of Keratin Genes in Human Epidermal Cells." In The Biology of Wool and Hair. Springer Netherlands, 1988. http://dx.doi.org/10.1007/978-94-011-9702-1_20.

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Parry, D. A. D. "Protein chains in hair and epidermal keratin IF: Structural features and spatial arrangements." In Formation and Structure of Human Hair. Birkhäuser Basel, 1997. http://dx.doi.org/10.1007/978-3-0348-9223-0_5.

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Conway, J. F., R. D. B. Fraser, T. P. Macrae, and D. A. D. Parry. "Protein Chains in Wool and Epidermal Keratin IF: Structural Features and Spatial Arrangement." In The Biology of Wool and Hair. Springer Netherlands, 1988. http://dx.doi.org/10.1007/978-94-011-9702-1_9.

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Matsuzawa, Takamitsu, Michiyo Nakano, Ayako Oikawa, Yuumi Nakamura, and Hiroyuki Matsue. "Three-Dimensional Epidermal Model from Human Hair Follicle-Derived Keratinocytes." In Skin Tissue Engineering. Springer New York, 2019. http://dx.doi.org/10.1007/978-1-4939-9473-1_10.

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Petersson, Monika, Daniela Frances, and Catherin Niemann. "Lineage Tracing of Hair Follicle Stem Cells in Epidermal Whole Mounts." In Skin Stem Cells. Humana Press, 2013. http://dx.doi.org/10.1007/978-1-62703-330-5_5.

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Conference papers on the topic "Epidermal hair"

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Petukhov, Valery I., and Egor V. Dmitriev. "Na,K-HOMEOSTASIS IN THE EPIDERMIS AS A PHENOMENON OF SELF-ORGANIZED CRITICALITY." In NOVEL TECHNOLOGIES IN MEDICINE, BIOLOGY, PHARMACOLOGY AND ECOLOGY. Institute of information technology, 2022. http://dx.doi.org/10.47501/978-5-6044060-2-1.267-271.

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Using atomic emission spectrometry, the content of sodium (Na) and potassium (K) in the epidermal derivative (hair) was measured in healthy individuals (9991 people). According to the spectrometry data, 4 groups were formed depending on the Na/K ratio: group 1 - Na/K <1 (n=1834); 2nd - Na/K from 1 to 5 (n=6884); 3rd – Na/K from 5 to 10 (n=893) and 4th – Na/K >10 (n=380). A correlation analysis (Pearson) of the tightness of the K-Na connection was carried out in the total sample (n=9991) and in each of the groups with different Na/K values. It was found that the correlation coefficient r
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hayder ALMEHANYA, Farqad, and Azhar Abdulameer SOSA. "ANATOMICAL STUDY OF THE EPIDERMIS LEAVES FOR SOME GENUS OF ASTERACEAE IN DIWANIYAH." In VI.International Scientific Congress of Pure,Applied and Technological Sciences. Rimar Academy, 2022. http://dx.doi.org/10.47832/minarcongress6-37.

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The current research includes anatomical study of epidermis of some genera that belong to the sunflower family Asteraceae (Compositae), which are Aster L., Calendula L., Dendranthema L., Helianthus L., Lactuca L., Launaea L. and Tagetes L.. And it was found that the anatomical characteristics have the importance of classification in the isolation of genera. The characteristic of undulation of the epidermal anticlincal cell walls of leaves was of great importance in isolation, and the study also showed some importance indumentum such as isolating Dendranthema L. from the rest of the genus becau
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Huang, Xiyong, Michael D. Protheroe, Ahmed M. Al-Jumaily, and Sharad P. Paul. "The Significance of Hair Thermal Diffusivity on Melanoma Incidence." In ASME 2017 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2017. http://dx.doi.org/10.1115/imece2017-71693.

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There is an increased risk of melanoma in adulthood when a child (pre-puberty) has been exposed to high levels of ultraviolet radiation (UVR). It has also been hypothesized that the childhood body air (vellus hair) plays a role in the increased incidence of melanoma later in life. This is attributed to the fact that the vellus hair has properties and physiology which encourage the transmission of harmful energy into the follicle of the hair and ultimately cause damage to the stem cells in residence there. Later in life these damaged stem cells become involved in the generation of melanomas in
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Jarvis, David, Angela Edwards, and Narayan Bhattarai. "Extraction and Production of Keratin-Based Nanofibers for Biomedical Applications." In ASME 2013 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/imece2013-64501.

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Keratin, a natural biomaterial found within the hair, nails, and epidermis of humans, has shown promise of being a useful material for tissue engineering scaffolds and drug delivery systems, due in part to its favorable biological qualities. The scaffolds generated by electrospinning are useful in proliferating cells, and can even biodegrade over time, reducing the impact on the body and not invoking any adverse tissue response. This research details the extraction process of keratin from human hair, and using electrospinning to weave the keratin into nanofibrous polymers. Using a synthetic po
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Kim, Sun Hye, Everardo Macías, Christopher Sistrunk, and Marcelo L. Rodriguez-Puebla. "Abstract 3889: Cyclin-dependent kinase 4 levels affect the number of hair follicle stem cells in mouse epidermis." In Proceedings: AACR 101st Annual Meeting 2010‐‐ Apr 17‐21, 2010; Washington, DC. American Association for Cancer Research, 2010. http://dx.doi.org/10.1158/1538-7445.am10-3889.

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Stead, Anthony D., Robin A. Cotton, Anton M. Page, Mike D. Dooley, and Thomas W. Ford. "Visualization of the effects of electron microscopy fixatives on the structure of hydrated epidermal hairs of tomato (lycopersicum peruvianum) as revealed by soft x-ray contact microscopy." In San Diego '92, edited by Chris J. Jacobsen and James E. Trebes. SPIE, 1993. http://dx.doi.org/10.1117/12.138751.

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