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Dissertations / Theses on the topic 'Eye lens'

Author: Grafiati

Published: 4 June 2021

Last updated: 25 July 2025

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1

Bateman, Orval. "The characterisation of eye lens crystallins." Thesis, Birkbeck (University of London), 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.301285.

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2

Keenan, Jonathan. "Crystallin distribution patterns in the eye lens." Thesis, University of Ulster, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.554261.

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The lens is an ideal tissue to study growth and ageing since it continually grows throughout life accumulating cells with no protein turnover. The lenticular structural proteins, the crystallins, are distributed in layers that follow a chronological pattern. In this thesis, crystallin distribution patterns were investigated in concentric fractions of eye lenses from nine species. Clear lenses were used in order to examine changes occurring with development and ageing without the confounding factor of cataract. For the majority of species studied this was the first study to investigate and iden

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3

Hott, John Lester. "Photochemical alterations of ocular lens proteins." Diss., Georgia Institute of Technology, 1991. http://hdl.handle.net/1853/30087.

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4

Tomlinson, Julie. "Calcium in relation to lens physiology and pathology." Thesis, University of East Anglia, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.292537.

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5

Chen, Wen-Lung. "Raman spectroscopic/imaging studies of eye lenses and lens proteins." Diss., Georgia Institute of Technology, 1991. http://hdl.handle.net/1853/30431.

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6

Wilson, Cynthia Nicole. "A Fully Customizable Anatomically Correct Model of the Crystalline Lens." Thèse, Université d'Ottawa / University of Ottawa, 2011. http://hdl.handle.net/10393/20130.

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The human eye is a complex optical system comprised of many components. The crystalline lens, an optical component with a gradient index (GRIN), is perhaps the least understood as it is situated inside the eye and as a result is difficult to characterize. Its complex nonlinear structure is not easily measured and consequently not easily modeled. Presently several models of the GRIN structure exist describing the average performance of crystalline lenses. These models, however, do not accurately describe the performance of crystalline lenses on an individual basis and a more accurate individual

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7

MacDonald, James Tomomi. "The unfolding and stability of eye lens crystallins." Thesis, Birkbeck (University of London), 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.427680.

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8

Chandler, Heather Lynn. "Epithelial-mesenchymal transition in the anterior segment of the eye." Columbus, Ohio : Ohio State University, 2006. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1154533588.

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9

Shu, Daisy Yao. "TGFβ, BMP and EGF interplay in the pathogenesis of fibrotic cataract: a tale of three growth factors". Thesis, The University of Sydney, 2019. http://hdl.handle.net/2123/20493.

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The ocular lens is bathed by a cocktail of growth factors, such as fibroblast growth factor (FGF), bone morphogenetic protein (BMP), insulin-like growth factor (IGF), epidermal growth factor (EGF) and transforming growth factor-beta (TGFβ) that differentially influence cellular behaviour. While some growth factors such as FGF, BMP and EGF facilitate normal physiological lens processes, TGFβ is unique in that it is a potent inducer of lens cell pathology, namely, epithelial-mesenchymal transition (EMT) leading to fibrotic cataract formation. The studies in this thesis primarily explore the intr

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10

Wederell, Elizabeth D. "Expression and role of integrins in lens development and cataractogenesis." Thesis, The University of Sydney, 2004. https://hdl.handle.net/2123/27986.

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The mammalian lens is composed of two types of cells enclosed within a thickened basement membrane known as the lens capsule. A monolayer of epithelial cells lines the anterior of the lens while the bulk of the lens is made up of lens fibre cells. After embryonic induction, the lens grows by the proliferation, posterior migration and differentiation of lens epithelial cells in the equatorial region into lens fibre cells. The central epithelium remains relatively quiescent. As fibre cells are formed, they are added to the fibre mass. Here they lose their nuclei and organelles and remain i

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11

Walker, Heather Mhairi. "Investigating the role of the lens in the growth and development of the vertebrate eye." Thesis, University of Aberdeen, 2014. http://digitool.abdn.ac.uk:80/webclient/DeliveryManager?pid=225773.

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The eye forms through complex tissue interactions, and it still only partly understood. The developing vertebrate lens however, is crucial for coordinating eye development and eye growth, through releasing signals to surrounding eye structures. It is thought that the lens controls the growth of the eye through the production of the vitreous- the jelly-like substance that fills the main cavity of the eye and maintains the eye in its correct shape. Many components of the vitreous are produced by a region of the peripheral retina known as the ciliary body, and so it is believed that the lens cont

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12

Sparrow, John Martin. "The lens in diabetes." Thesis, University of Oxford, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.238162.

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13

Lin, Valentine, and Hamad Tarek Sayed. "3D Printing a Maxwell Fish Eye Lens With Periodic Structures." Thesis, KTH, Skolan för elektroteknik och datavetenskap (EECS), 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-254262.

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With the rise of high frequency communication systems such as 5G, new types of antennas has to be developed in order to meet the new requirements. In recent years, lens antennas made of periodic structures has been shown to have desirable performance when increasing operational frequency without increasing the size of the antennas. One way of manufacturing the lenses for the antennas are with 3D printers loaded with dielectrics with specified permittivity. This project group studied the process of designing and manufacturing a flat Maxwell fish eye lens at 5 GHz with a bandwidth of 3.5 GHz to

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14

Nichols, Jason Jay. "Evaporative tear film and contact lens factors associated with dry eye symptoms in contact lens wearers." The Ohio State University, 2004. http://rave.ohiolink.edu/etdc/view?acc_num=osu1085771728.

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15

Banks, Eric A. "Connexin 45.6 in lens development : a dissertation /." San Antonio : UTHSC, 2007. http://proquest.umi.com/pqdweb?did=1400957401&sid=1&Fmt=2&clientId=70986&RQT=309&VName=PQD.

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16

Nichols, Jason J. "Evaporative tear film and contact lens factors associated with dry eye symptoms in contact lens wearers." Connect to this title online, 2004. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1085771728.

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Thesis (Ph. D.)--Ohio State University, 2004.<br>Title from first page of PDF file. Document formatted into pages; contains xiii, 122 p.; also includes graphics Includes bibliographical references (p. 80-94). Available online via OhioLINK's ETD Center

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17

Slight, S. H. "Biochemical studies on the mammalian lens." Thesis, University of Salford, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.381703.

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18

Sousounis, Konstantinos. "Gene Expression During Newt Lens Regeneration and Cephalopod Eye Evolution." University of Dayton / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=dayton1405702826.

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19

Principi, Sara. "Development of methodologies for estimating the dose to the eye lens in interventional radiology : operational implications of the eye lens new dose limit." Doctoral thesis, Universitat Politècnica de Catalunya, 2017. http://hdl.handle.net/10803/620729.

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Recent epidemiological evidences on very late opacities or cataract manifestation, has led to a review of the actual limit for the eye lens (150 mSv/year) for workers exposed to ionizing radiation. ICRP 118 recommends reducing the limit to 20 mSv per year. This drastic change in the dose limit has been incorporated into the revised European and International Basic Safety Standards (European Commission 2013, International Atomic Energy Agency 2014) and it should be implemented in national legislation of member states in 2018. Up to now, eye lens dose is not routinely measured and there are no g

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20

Li, Dongyun. "The effect of UV-laser radiation on lenses and lens proteins." Thesis, Georgia Institute of Technology, 1989. http://hdl.handle.net/1853/27271.

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21

McClure, Kate Alexandra. "Tear Film Dynamics Associated with Contact Lens Wear." The Ohio State University, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=osu1523579680091666.

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22

Bergbauer, Katrina L. "Laser raman spectroscopic studies of ocular lens aging and cataractogenesis." Diss., Georgia Institute of Technology, 1991. http://hdl.handle.net/1853/30031.

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23

Poey, S. M. "Infrared thermography of the anterior eye during contact lens wear." Thesis, University of Manchester, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.494480.

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24

Evans, Paul James. "Circular dichroism spectroscopy studies of the eye lens crystallin proteins." Thesis, Birkbeck (University of London), 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.437767.

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Circular dichroism spectroscopy is an established technique that is frequently used in the analysis of the confonnation of biological molecules. It has previously been reported that the deconvolution of circular dichroism spectra of vertebrate eye lens P'rcrystallin proteins gives exceptionally poor results, and that these spectra are heavily influenced by aromatic contributions in the far-ultraviolet. This thesis describes work undertaken to assess to what extent circular dichroism spectra of py-crystallins can be rationalised in tenus of secondary structure, and to determine if circular dich

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25

Greenlees, Rebecca. "Characterisation of a gene critical in eye and lens development." Thesis, The University of Sydney, 2014. http://hdl.handle.net/2123/12051.

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Visual impairment or blindness caused by vision disorders affect over 500,000 Australians, with approximately one-third caused by genetic eye disorders. Previous work identified a cataract and anterior segment abnormality patient with a de novo balanced chromosomal translocation transecting the 5’ UTR of a novel candidate disease gene. An expression vector containing the candidate gene and a GFP tag revealed its subcellular localisation to the plasma membrane domain of two epithelial cell lines. Colocalisation experiments showed colocalisation of the candidate disease gene with proteins of ad

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26

Moffat, Bradford Armstrong. "Nuclear magnetic resonance micro-imaging of the human eye lens." Thesis, Queensland University of Technology, 2001. https://eprints.qut.edu.au/37073/1/37073_Digitised%20Thesis.pdf.

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The exact causes of presbyopia and the development of senile cataract are still unclear. In this project magnetic resonance microscopy (MRM) has been used to study the kinetics of long-range water transport, anisotropic diffusion and refractive index distribution in the human eye lens. A decline in the transpmi process, changes to the nature of anisotropic diffusion and changes to the refractive index distribution in the lens may all be related to the onset of presbyopia and cataract. The results of the long-range water transport experiments showed that as lenses age there is reduction i

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27

Maksimovic, Srdjan. "Unusual eye design: The compound-lens eyes of Strepsiptera and the scanning eyes of Sunburst Diving Beetle larvae." University of Cincinnati / OhioLINK, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1285687000.

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28

Wei, Kang. "Bio-inspired Reconfigurable Elastomer-liquid Lens: Design, Actuation and Optimization." The Ohio State University, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=osu1429657034.

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29

Wang, Qian. "Role of growth factors in regulating of lens fibre differentiation." Thesis, The University of Sydney, 2008. https://hdl.handle.net/2123/28141.

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The lens is a good developmental biology model owing to its simplicity and distinct polarity. The anterior lens compartment constitutes a monolayer of cuboidal-shaped epithelial cells, which overly a mass of precisely aligned elongated fibre cells. Lens growth throughout life is mediated by proliferation of epithelial cells and their subsequent differentiation into fibres, to form a transparent and tightly-packed lens. During lens growth and development, cell proliferation is mainly restricted to a specialised region at the periphery of the lens epithelium known as the gerrninative zone.

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30

Fisher, Damien. "The influence of scleral lens parameters and fitting characteristics on corneal oedema under open and closed eye conditions." Thesis, Queensland University of Technology, 2021. https://eprints.qut.edu.au/211357/1/Damien_Fisher_Thesis.pdf.

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Scleral lenses are large rigid contact lenses used to treat diseases that affect the front surface of the eye. This thesis examined how scleral lens fitting characteristics can be optimised to reduce corneal tissue swelling. The results provide clinical guidance for contact lens practitioners and patients worldwide.

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31

Adnan, X. "Optics of the human eye in diabetes." Thesis, Queensland University of Technology, 2015. https://eprints.qut.edu.au/79899/1/_Adnan_Thesis.pdf.

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This study compared optics of eyes in people with diabetes with those age-balanced controls. Relative to the control group, the diabetes group demonstrated greater lens thickness, more curved lens shapes, smaller lens diameters, higher light scatter, greater lens yellowing, and poorer focusing ability. While the optics of the people with diabetes made them appear as older eyes than those of people of the same age without diabetes, the differences did not increase significantly with age. It was concluded that age-related changes in eyes of people with diabetes need not be accelerated if the dia

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32

Srikanthan, Durga. "Structural studies of small heat shock proteins and eye lens crystallins." Thesis, Birkbeck (University of London), 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.414501.

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33

Najmudin, Shabir. "A structural analysis of eye lens proteins : refinement of yB crystallin." Thesis, Birkbeck (University of London), 1993. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.740998.

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34

Hook, Darren W. A. "Protection of enzymes by the molecular chaperone #alpha#-Crystalline." Thesis, University of Oxford, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.300133.

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35

Wazin, Fatima. "Spred: a negative regulator of cellular processes involved in lens and eye development." Thesis, University of Sydney, 2020. https://hdl.handle.net/2123/22989.

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The transparent and refractive properties of the lens are extremely dependent on the its precise cellular structure, with constant regulation of cell behaviour throughout life. Cell signalling pathways play a crucial role in regulating cellular processes in both mammalian growth and development, and are in turn frequently regulated by inhibitory molecules, including the Spred family, to modulate and attenuate the impact of growth factor stimulation. Due to Spred’s strong expression in lens and its ability to negatively regulate growth factor-induced ERK/MAPK pathways that are essential for man

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36

Alzahrani, Yahya A. "In vivo assessment of inflammatory cells in contact lens wearers." Thesis, Queensland University of Technology, 2016. https://eprints.qut.edu.au/93576/1/Yahya_Alzahrani_Thesis.pdf.

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Dissatisfaction with, and discontinuation from, contact lens wear is a source of major frustration and inconvenience to users, and a problem that is thought to cost the contact lens industry hundreds of millions of dollars each year. By directly and non-invasively monitoring inflammatory cells in the tissues at the front of the eye in symptomatic and asymptomatic lens wearers, the candidate has been able to demonstrate an inflammatory basis for contact lens discomfort. This finding may pave the way towards the development of strategies to make contact lenses more safe and afford greater levels

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37

Miranda, Marco A. L. A. E. "Structural and Optical Changes in the Eye with Soft Contact Lens Wear." Thesis, University of Manchester, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.532229.

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38

Hennelly, Michelle Louise. "The light scattering characteristics of the normal and contact lens-wearing eye." Thesis, City University London, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.367322.

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39

Kivlan, Anna Karrer. "An eye for vulgarity : how MoMA saw color through Wild Bill's lens." Thesis, Massachusetts Institute of Technology, 2007. http://hdl.handle.net/1721.1/39314.

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Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Architecture, 2007.<br>Includes bibliographical references (p. 67-71).<br>This thesis is an examination of the 1976 Museum of Modern Art exhibition of color photographs by William Eggleston-the second one-man show of color photography in the museum's history- with particular attention to the exhibition monograph, William Eggleston's Guide. From hundreds of slides, MoMA Director of Photography John Szarkowski dominated the process of selecting the 75 images for the exhibition and 48 to be carefully packaged in the Guide, a faux fami

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40

Best, Nigel. "The predictive ability of clinical tests for contact lens induced dry eye." Thesis, Aston University, 2013. http://publications.aston.ac.uk/19599/.

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Approximately half of current contact lens wearers suffer from dryness and discomfort, particularly towards the end of the day. Contact lens practitioners have a number of dry eye tests available to help them to predict which of their patients may be at risk of contact lens drop out and advise them accordingly. This thesis set out to rationalize them to see if any are of more diagnostic significance than others. This doctorate has found: (1) The Keratograph, a device which permits an automated, examiner independent technique for measuring non invasive tear break up time (NITBUT) measured NITBU

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41

Barron, Brent Christian. "Characterization of normal aging and cataractous processes in the eye lens by laser raman spectroscopy." Diss., Georgia Institute of Technology, 1988. http://hdl.handle.net/1853/30052.

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42

Derham, Barry K. "The effects of ageing on #alpha#-crystallin, a molecular chaperone." Thesis, University of Oxford, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.325297.

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43

Sandilands, Aileen. "Characterisation of the intermediate filament proteins filensin and CP49 within the eye lens." Thesis, University of Dundee, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.441633.

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44

Pult, Heiko. "The predictive ability of clinical tests for dry eye in contact lens wear." Thesis, Cardiff University, 2008. http://orca.cf.ac.uk/54731/.

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Thirty to fifty percent of contact lens wearers discontinue contact lens wear. Therefore it is essential for the clinician to have a predictive method that can forecast the development of dryness symptoms in contact lens wear. Contact lens wear induces tear film instability leading to increased tear film evaporation and its associated hyperosmolarity. This in turn causes ocular surface inflammation resulting in the release of cytokines, impacting tear mucin production, which further destabilises the tear film. Since this mechanism can only be fully evaluated by an intensive laboratory-based ap

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45

Mizdrak, Jasminka. "Human lens chemistry: UV filters and age-related nuclear cataract." Australia : Macquarie University, 2007. http://hdl.handle.net/1959.14/16855.

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"A thesis submitted in partial fulfillment of the requirements for the award of the degree of Doctor of Philosophy".<br>Thesis (PhD) -- Macquarie University, Division of Environmental and Life Sciences, Dept. of Chemistry and Biomolecular Sciences, 2007.<br>Bibliography: p. 243-277.<br>Introduction -- A convenient synthesis of 30HKG -- Facile synthesis of the UV filter compounds 30HKyn and AHBG -- Synthesis, identification and quantification of novel human lens metabolites -- Modification of bovine lens protein with UV filters and related metabolites -- Effect of UV light on UV filter-treated

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46

Oppermann, Brian P. "Identification, localization and metal catalyzed induction of specific metallothionein isoforms expressed by the adult human lens." Morgantown, W. Va. : [West Virginia University Libraries], 2001. http://etd.wvu.edu/templates/showETD.cfm?recnum=1846.

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Thesis (M.S.)--West Virginia University, 2001.<br>Title from document title page. Document formatted into pages; contains vi, 43 p. : ill. (some col.). Includes abstract. Includes bibliographical references (p. 37-43).

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47

Hager, Michele LynnManeca. "A Study of Contact Lens Comfort in Patients Wearing Comfilcon A Soft Contact Lenses Compared to Their Habitual Soft Contact Lenses." The Ohio State University, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=osu1243711014.

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48

Schultz, Kristin E. "Accommodative microfluctuations, crystalline lens tension, ciliary body thickness, and refractive error in children." Columbus, Ohio : Ohio State University, 2009. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1240445960.

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49

Dube, Zack. "Computational Reconstruction of the Physical Eye Using a New Gradient Index of Refraction Model." Thesis, Université d'Ottawa / University of Ottawa, 2016. http://hdl.handle.net/10393/34791.

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This thesis proposes and tests an individually customizable model of the human crystalline lens. This model will be crucial in developing both research on the human eye and driving diagnostic tools to help plan and treat optical issues, such as those requiring refractive surgery. This thesis attempts to meet two goals: first, it will determine whether this new lens model can reproduce the major aberrations of real human eyes using a computational framework. Second, it will use clinical information to measure how well this model is able to predict post-operation results in refractive surgery

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50

Rueff, Erin. "Contact lens induced dry eye and binocular vision disorders: A study of similar symptoms." The Ohio State University, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=osu1397167126.

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