Academic literature on the topic 'Fetal Fibroblast'

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Journal articles on the topic "Fetal Fibroblast"

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Fabisiak, J. P., M. Absher, J. N. Evans, and J. Kelley. "Spontaneous production of PDGF A-chain homodimer by rat lung fibroblasts in vitro." American Journal of Physiology-Lung Cellular and Molecular Physiology 263, no. 2 (1992): L185—L193. http://dx.doi.org/10.1152/ajplung.1992.263.2.l185.

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Platelet-derived growth factor (PDGF) is considered a decisive mediator of fibroblast growth and phenotype within the lung. The cellular sources of PDGF within the lung remain undefined. The ability of lung fibroblasts themselves to produce PDGF in vitro was therefore investigated. Northern and Western blot analyses revealed the expression of PDGF-A mRNA and secretion of A-chain containing proteins by fibroblasts derived from adult and fetal rat lung. PDGF-A gene or protein expression were below the limits of detection in two human lung fibroblast lines examined in a similar manner. PDGF-B tra
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Navarro, Angels, Mo Rezaiekhaligh, J. Andrew Keightley, Sherry M. Mabry, Ricardo E. Perez, and Ikechukwu I. Ekekezie. "Higher TRIP-1 level explains diminished collagen contraction ability of fetal versus adult fibroblasts." American Journal of Physiology-Lung Cellular and Molecular Physiology 296, no. 6 (2009): L928—L935. http://dx.doi.org/10.1152/ajplung.00012.2009.

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Acute lung injury involving extremely immature lungs often heals without excessive fibrosis unlike later in gestation and in adults. Several factors may be involved, but fibroblast contraction of collagen has been linked to the level of wound fibrosis. To assess whether human lung fibroblasts of fetal versus adult origin differ in ability to contract collagen and define the molecular underpinnings, we performed three-dimensional collagen contraction assay, analyzed their differential mRNA profile, specifically for transforming growth factor-β (TGF-β) signaling pathway and extracellular matrix
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Irwin, C. R., M. Picardo, I. Ellis, et al. "Inter- and intra-site heterogeneity in the expression of fetal-like phenotypic characteristics by gingival fibroblasts: potential significance for wound healing." Journal of Cell Science 107, no. 5 (1994): 1333–46. http://dx.doi.org/10.1242/jcs.107.5.1333.

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We have previously reported that fetal and adult skin fibroblasts display distinctive migratory phenotypes on 3-D collagen substrata and that these behavioural characteristics may be quantified by a function defined as the cell density migration index (CDMI). Subsequent work indicated that this difference in migratory phenotype was due to the production by fetal fibroblasts of a migration stimulating factor (MSF) that is not produced by normal adult skin fibroblasts. We now present data indicating that: (a) unselected fibroblasts obtained from 14/14 (100%) of adult gingival explants expressed
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Rettig, W. J., H. P. Erickson, A. P. Albino, and P. Garin-Chesa. "Induction of human tenascin (neuronectin) by growth factors and cytokines: cell type-specific signals and signalling pathways." Journal of Cell Science 107, no. 2 (1994): 487–97. http://dx.doi.org/10.1242/jcs.107.2.487.

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The extracellular matrix protein tenascin (TN) is expressed with precise temporo-spatial patterns during embryonic and fetal development and is induced in healing wounds, inflammatory lesions and solid tumors. These tissue patterns suggest that TN synthesis may be modulated by soluble factors present in developing tissues or released from injured, inflammatory or neoplastic cells. To characterize the extrinsic control of human TN we examined the effects of several signalling molecules on cultured neural, melanocytic and fibroblastic cells. Results obtained with alpha TN antibodies in enzyme-li
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Lorenz, H. Peter, Richard Y. Lin, Michael T. Longaker, David J. Whitby, and N. Scott Adzick. "The Fetal Fibroblast." Plastic and Reconstructive Surgery 96, no. 6 (1995): 1251–59. http://dx.doi.org/10.1097/00006534-199511000-00001.

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Das, M., K. R. Stenmark, and E. C. Dempsey. "Enhanced growth of fetal and neonatal pulmonary artery adventitial fibroblasts is dependent on protein kinase C." American Journal of Physiology-Lung Cellular and Molecular Physiology 269, no. 5 (1995): L660—L667. http://dx.doi.org/10.1152/ajplung.1995.269.5.l660.

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The earliest and most striking proliferative changes in the neonatal pulmonary arterial wall occur in the adventitia where the fibroblast resides. The protein kinase C (PKC) pathway is developmentally regulated and important in vascular cell growth. We tested the hypothesis that developmental differences in growth of pulmonary artery adventitial fibroblasts would be detectable in vitro and dependent on PKC. Fibroblasts were isolated from bovine fetal, neonatal, and adult pulmonary arteries. Growth was measured by [3H]thymidine incorporation and cell counts. Under serum-stimulated conditions, f
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Caniggia, I., I. Tseu, R. N. Han, B. T. Smith, K. Tanswell, and M. Post. "Spatial and temporal differences in fibroblast behavior in fetal rat lung." American Journal of Physiology-Lung Cellular and Molecular Physiology 261, no. 6 (1991): L424—L433. http://dx.doi.org/10.1152/ajplung.1991.261.6.l424.

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Fibroblast-epithelial interactions were investigated in cells from late-gestation fetal rat lung. Fibroblasts from the pseudoglandular stage of lung development stimulated epithelial cell proliferation, whereas fibroblasts from the saccular stage promoted epithelial cell differentiation. The developmental switch from proliferation to differentiation seemed to be controlled by both cell types. Fibroblast-derived epithelial cell growth-promoting activity, evident in cells from the pseudoglandular period, decreased during development and almost disappeared in cells from the saccular stage. Intere
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Ellis, I., J. Banyard, and S. L. Schor. "Differential response of fetal and adult fibroblasts to cytokines: cell migration and hyaluronan synthesis." Development 124, no. 8 (1997): 1593–600. http://dx.doi.org/10.1242/dev.124.8.1593.

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Previous studies have indicated that fetal skin fibroblasts display an elevated level of migratory activity compared to adult cells and that this may result from inherent differences in the production of hyaluronan (HA) by these cells. Data presented in this communication indicate that the elevated level of fetal fibroblast migration into 3D-collagen gels and HA synthesis by these cells were not affected by epidermal growth factor (EGF), platelet-derived growth factor (PDGF), acidic fibroblast growth factor (aFGF) or basic fibroblast growth factor (bFGF). In contrast, both cell migration and H
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Chen, Xi, Nathalie Hirt-Burri, Corinne Scaletta, Alexis E. Laurent, and Lee Ann Applegate. "Bicomponent Cutaneous Cell Therapy for Early Burn Care: Manufacturing Homogeneity and Epidermis-Structuring Functions of Clinical Grade FE002-SK2 Allogeneic Dermal Progenitor Fibroblasts." Pharmaceutics 17, no. 6 (2025): 692. https://doi.org/10.3390/pharmaceutics17060692.

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Background: The extracellular matrix (ECM), primarily composed of collagen and elastin synthesized by dermal fibroblasts, is critical for mesenchymal tissue integrity. Fibroblast phenotypes vary significantly with the anatomical location and developmental stage. Fetal skin, particularly prior to 14 weeks of gestation, exhibits a simplified structure compared to adult skin, characterized by a thin, loose dermal matrix and a single-layered epithelium. Objectives: This study aimed to characterize and functionally compare homogenous progenitor fetal fibroblast (PFF) populations derived from 14-wee
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Kelley, J., J. P. Fabisiak, K. Hawes, and M. Absher. "Cytokine signaling in lung: transforming growth factor-beta secretion by lung fibroblasts." American Journal of Physiology-Lung Cellular and Molecular Physiology 260, no. 2 (1991): L123—L128. http://dx.doi.org/10.1152/ajplung.1991.260.2.l123.

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Control of growth and phenotypic expression of interstitial fibroblasts is a critical determinant of lung architecture and physiology during processes of growth and remodeling. We examined the ability of lung fibroblasts to produce transforming growth factor-beta (TGF-beta), a cytokine that is known to modulate proliferation and phenotypic expression of mesenchymal cells. Cultures of fibroblasts isolated from rat lungs spontaneously secrete TGF-beta as measured in the standard bioassay of anchorage-independent growth of normal rat kidney (NRK) cells in soft agar. Rat lung fibroblasts secrete T
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Dissertations / Theses on the topic "Fetal Fibroblast"

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Maker, Garth Lucas. "Regulation of surfactant production by fetal type II pneumocytes and characterization of fibroblast-pneumocyte factor /." Access via Murdoch University Digital Theses Project, 2007. http://wwwlib.murdoch.edu.au/adt/browse/view/adt-MU20080430.141113.

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Franke, Jana, Vanessa Abs, Claudia Zizzadoro, and Getu Abraham. "Comparative study of the effects of fetal bovine serum versus horse serum on growth and differentiation of primary equine bronchial fibroblasts." Universitätsbibliothek Leipzig, 2014. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-144893.

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Background: Airway fibroblasts have become a critical addition to all facets of structural lung tissue changes such as in human asthma and chronic obstructive pulmonary disease, but little is known about their role in the equine recurrent airway obstruction, a disease that resembles to the human asthma. Since the equine bronchial fibroblasts (EBF) have not been isolated and characterized yet, the use of defined medium was investigated. Results: Primary EBF were cultured on non-collagen coated flasks without serum or in the presence of feta bovine serum (FBS) or horse serum (HS) or in serum dep
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au, G. Maker@murdoch edu, and Garth Lucas Maker. "Regulation of surfactant production by fetal type II pneumocytes and the characterization of fibroblast-pneumocyte factor." Murdoch University, 2008. http://wwwlib.murdoch.edu.au/adt/browse/view/adt-MU20080430.141113.

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The fetal lung undergoes extensive physiological and biochemical maturation prior to birth in preparation for its postnatal function as an organ for gas exchange. Pulmonary surfactant, a substance that reduces surface tension and prevents alveolar collapse, is produced by type II pneumocytes within the lung. Reduced ability to produce surfactant leads to neonatal respiratory distress syndrome. Synthesis of the phospholipid component of surfactant, phosphatidylcholine (PC), is stimulated by fibroblast-pneumocyte factor (FPF), a protein expressed by fibroblast cells within the fetal lung. Althou
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Maker, Garth Lucas. "Regulation of surfactant production by fetal type II pneumocytes and the characterization of fibroblast-pneumocyte factor." Thesis, Maker, Garth Lucas ORCID: 0000-0003-1666-9377 (2008) Regulation of surfactant production by fetal type II pneumocytes and the characterization of fibroblast-pneumocyte factor. PhD thesis, Murdoch University, 2008. https://researchrepository.murdoch.edu.au/id/eprint/486/.

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The fetal lung undergoes extensive physiological and biochemical maturation prior to birth in preparation for its postnatal function as an organ for gas exchange. Pulmonary surfactant, a substance that reduces surface tension and prevents alveolar collapse, is produced by type II pneumocytes within the lung. Reduced ability to produce surfactant leads to neonatal respiratory distress syndrome. Synthesis of the phospholipid component of surfactant, phosphatidylcholine (PC), is stimulated by fibroblast-pneumocyte factor (FPF), a protein expressed by fibroblast cells within the fetal lung. Althou
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Maker, Garth Lucas. "Regulation of surfactant production by fetal type II pneumocytes and the characterization of fibroblast-pneumocyte factor." Maker, Garth Lucas (2008) Regulation of surfactant production by fetal type II pneumocytes and the characterization of fibroblast-pneumocyte factor. PhD thesis, Murdoch University, 2008. http://researchrepository.murdoch.edu.au/486/.

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The fetal lung undergoes extensive physiological and biochemical maturation prior to birth in preparation for its postnatal function as an organ for gas exchange. Pulmonary surfactant, a substance that reduces surface tension and prevents alveolar collapse, is produced by type II pneumocytes within the lung. Reduced ability to produce surfactant leads to neonatal respiratory distress syndrome. Synthesis of the phospholipid component of surfactant, phosphatidylcholine (PC), is stimulated by fibroblast-pneumocyte factor (FPF), a protein expressed by fibroblast cells within the fetal lung. Althou
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Schmidt, Joachim. "A novel binding protein for fibroblast growth factors (FGF-BP2) cloning, expression profile, tumorigenic activity and regulation of gene expression by fetal bovine serum and retinoic acid /." [S.l.] : [s.n.], 2003. http://archiv.ub.uni-marburg.de/diss/z2003/0713/.

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Mello, Marco Roberto Bourg de. ""Clonagem em bovinos: uso de fibroblastos fetal e adulto como fonte doadora de núcleo"." Universidade de São Paulo, 2003. http://www.teses.usp.br/teses/disponiveis/10/10131/tde-29062005-161626/.

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O objetivo deste estudo foi avaliar a viabilidade in vitro e in vivo de embriões bovinos reconstruídos com oócitos enucleados em Metáfase II e núcleos de células somáticas (fibroblastos) fetais e adultas. Para tanto, oócitos de ovários colhidos em matadouro foram maturados in vitro por 17 horas e enucleados pela remoção do primeiro corpúsculo polar (CP) e da região do oolema contendo a placa metafásica. Como núcleo doador, foram utilizados fibroblastos de orelha de vaca da raça Nelore e de feto colhido em abatedouro. Para a reconstrução dos embriões, cada célula doadora de núcleo, após indução
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Zaunbrecher, Gretchen Marie. "Comparison of several protocols for the increase in homologous recombination in normal porcine fetal fibroblasts and the application to an actual locus." Diss., Texas A&M University, 2003. http://hdl.handle.net/1969.1/76.

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Together with the advancements in animal cloning, the ability to efficiently target specific genes in somatic cells would greatly enhance several areas of research. While it has been possible for quite some time to target specific genes in the germ cells of mice, the advancements in somatic cell gene targeting has been slowed for two main reasons. First, the finite lifespan of somatic cells, due mainly to the inability of the somatic cells to regenerate or maintain their telomeres, poses a major problem given the lengthy selection process needed to identify a targeting event. The second pro
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Montenegro, Luciana Ribeiro. "Estudo in vitro da sensibilidade ao IGF-1 de fibroblastos de crianças nascidas pequenas para a idade gestacional sem recuperação estatural pós-natal." Universidade de São Paulo, 2009. http://www.teses.usp.br/teses/disponiveis/5/5135/tde-08092009-132008/.

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Introdução: Crianças nascidas pequenas para a idade gestacional (PIG) apresentam maior risco de permanecerem com baixa estatura na vida adulta. Os fatores de crescimento insulino-símile tipo 1 e 2 (IGF-1 e IGF-2) são os principais fatores endócrinos determinantes do crescimento fetal. A maioria das ações conhecidas do IGF-1 e 2 é mediada via um receptor tirosina quinase, conhecido como IGF-1R. Recentemente, a insensibilidade ao IGF-1 foi identificada como uma das causas de retardo de crescimento em crianças nascidas PIG que não apresentaram recuperação espontânea do crescimento na vida pós-nat
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Cavallin, Mara. "Physiopathologie moléculaire et cellulaire des anomalies du développement du cortex cérébral : le syndrome d'Aicardi WDR81 mutations cause extreme microcephaly and impair mitotic progression in human fibroblasts and Drosophila neural stem cells TLE1, a key player in neurogenesis, a new candidate gene for autosomal recessive postnatal microcephaly Mutations in TBR1 gene leads to cortical malformations and intellectual disability Aicardi syndrome: Exome, genome and RNA-sequencing of a large cohort of 19 patients failed to detect the genetic cause Recurrent RTTN mutation leading to severe microcephaly, polymicrogyria and growth restriction Recurrent KIF2A mutations are responsible for classic lissencephaly Recurrent KIF5C mutation leading to frontal pachygyria without microcephaly Rare ACTG1 variants in fetal microlissencephaly De novo TUBB2B mutation causes fetal akinesia deformation sequence with microlissencephaly: An unusual presentation of tubulinopathy A novel recurrent LIS1 splice site mutation in classic lissencephaly Further refinement of COL4A1 and COL4A2 related cortical malformations Prenatal and postnatal presentations of corpus callosum agenesis with polymicrogyria caused By EGP5 mutation Delineating FOXG1 syndrome from congenital microcephaly to hyperkinetic encephalopathy Delineating FOXG1 syndrome: From congenital microcephaly to hyperkinetic encephalopathy." Thesis, Sorbonne Paris Cité, 2019. https://wo.app.u-paris.fr/cgi-bin/WebObjects/TheseWeb.woa/wa/show?t=2213&f=18201.

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Les malformations du cortex cérébral (MDC) représentent une cause importante de handicap et d'épilepsie pharmaco-résistante. Le séquençage à haut débit a permis une amélioration considérable de l'identification des bases moléculaires des MDC non syndromiques. Toutefois, certaines formes, notamment les MDC complexes, demeurent inexpliquées. Mon projet de thèse a pour objectif de progresser dans la compréhension des MDC complexes en utilisant deux modèles : les microlissencéphalies (MLIS) et le syndrome d'Aicardi (AIC), une forme syndromique particulière associant des malformations de l'oeil et
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Books on the topic "Fetal Fibroblast"

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Lopez, Cecilia Ang. Agents enhancing oncogene-induced transformation of cultured rodent fibroblasts: Purification of a fetal calf serum. 1987.

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Book chapters on the topic "Fetal Fibroblast"

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Ulrich, Magda M. W. "Fetal Wound Healing." In Textbook on Scar Management. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-44766-3_1.

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AbstractFirst- and second-trimester fetal skin wounds are known to heal without scarring.Research has excluded factors like the sterile uterine environment as the cause of scarless repair, and it is believed that scarless healing is an intrinsic property of early fetal skin. However, increasing wound size and induction of the inflammatory reaction can evoke a scar response in the fetus.For decades, research is performed to elucidate the mechanisms responsible for scarless healing in fetuses. Much research has been performed in animal studies, and several mechanisms have been proposed to be inv
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Goodarzi, Parisa, Hamid Reza Aghayan, Moloud Payab, et al. "Human Fetal Skin Fibroblast Isolation and Expansion for Clinical Application." In Methods in Molecular Biology. Springer US, 2019. http://dx.doi.org/10.1007/7651_2019_233.

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Parker, Thomas G., King-Lau Chow, Robert J. Schwartz та Michael D. Schneider. "TGF-β1 and Fibroblast Growth Factors Selectively Up-Regulate Tissue-Specific Fetal Genes in Cardiac Muscle Cells". У Ciba Foundation Symposium 157 - Clinical Applications of TGF-β. John Wiley & Sons, Ltd., 2007. http://dx.doi.org/10.1002/9780470514061.ch10.

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Matsuda, Susumu, Hiroshi Saito, and Nobuyoshi Nishiyama. "Effect of Basic Fibroblast Growth Factor on Midbrain and Other CNS Neurons in Primary Culture Derived from Postnatal and Fetal Rat Brain." In Basic, Clinical, and Therapeutic Aspects of Alzheimer’s and Parkinson’s Diseases. Springer US, 1990. http://dx.doi.org/10.1007/978-1-4684-5847-3_102.

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Dolleman-Van Der Weel, M. J., A. Nijssen, J. De Vente, et al. "Morphological and Behavioral Effects of Basic Fibroblast Growth Factor and Heparin on Transplanted Fetal Dopaminergic Neurons and Astrocytes in the Denervated Rat Caudate-Putamen." In Growth Factors and Alzheimer’s Disease. Springer Berlin Heidelberg, 1991. http://dx.doi.org/10.1007/978-3-642-46722-6_13.

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Legault, Emilie M., and Janelle Drouin-Ouellet. "Generation of Induced Dopaminergic Neurons from Human Fetal Fibroblasts." In Methods in Molecular Biology. Springer US, 2021. http://dx.doi.org/10.1007/978-1-0716-1601-7_7.

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Taghiabadi, Ehsan, Bahareh Beiki, Nasser Aghdami, and Amir Bajouri. "Amniotic Membrane Seeded Fetal Fibroblasts as Skin Substitute for Wound Regeneration." In Skin Stem Cells. Springer New York, 2018. http://dx.doi.org/10.1007/7651_2018_135.

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Schor, Seth L., Anne Marie Grey, Ian Ellis, et al. "Fetal-like fibroblasts: Their production of migration-stimulating factor and role in tumor progression." In Cancer Treatment and Research. Springer US, 1994. http://dx.doi.org/10.1007/978-1-4615-2592-9_15.

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Miura, Shizuka, and Atsushi Suzuki. "Direct Lineage Reprogramming of Mouse Fibroblasts to Acquire the Identity of Fetal Intestine-Derived Progenitor Cells." In Methods in Molecular Biology. Springer US, 2020. http://dx.doi.org/10.1007/978-1-0716-0747-3_14.

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"Cytotoxic activity of macrocyclic Lu (III) complexes." In Book of Abstracts - RAD 2025 Conference. RAD Centre, Niš, Serbia, 2025. https://doi.org/10.21175/rad.abstr.book.2025.21.2.

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Aim: Two newly synthesized complexes [[Lu2tpmcCl2(H2O)2](BF4)4∙2NaBF4 and [Lucyc(H2O)2] (BF4)3∙NaBF4 were tested against human lung carcinoma cell line A549 and the non-malignant, human lung fibroblast cell line MRC-5. The values of IC50 were calculated. Material and Methods. Cell Culture. The human lung carcinoma cell line A549 (CCL-185) and the non-malignant human lung fibroblast cell line MRC-5 (CCL-171) were procured from the American Type Culture Collection. The cells were grown in Dulbecco's Modified Eagle Medium (DMEM), supplemented with 10% fetal bovine serum, and a solution of penicil
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Conference papers on the topic "Fetal Fibroblast"

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Muszbek, L., and R. Adány. "CELLULAR DISTIBUTION OF FACTOR XIII IN HUMAN UTERUS AND PLACENTA." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644648.

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As spontaneous abortion is a frequent finding in females with Factor XIII (FXIIl) deficiency it has been presumed that the plasmatic or cellular form of this clotting factor is essential to normal fetus development. In this context it is of special interestthat FXIII subunit a has been demonstrated in the homoge-nate of human uterus and placenta by activity measurements and immunobiochemical methods. However, no information on its cellular distribution has beenpublished, so far. In the present study first FXIII subunit a was detected in paraformaldehyde-fixed, paraffin-embedded sections by imm
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Firl, Christina, Robert Clancy, and Jill Buyon. "1302 Fetal cardiac and neonatal dermal fibroblast phenotypes and cytokine reactivity following macrophage crosstalk in the pathogenesis of neonatal lupus." In Lupus 21st Century 2023 Abstracts, September 27–30, Naples, Florida. Lupus Foundation of America, 2024. http://dx.doi.org/10.1136/lupus-2023-lupus21century.90.

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You, K., P. Parikh, K. Khandalavala, et al. "Moderate Hyperoxia Induces Senescence in Human Fetal Lung Fibroblasts." In American Thoracic Society 2019 International Conference, May 17-22, 2019 - Dallas, TX. American Thoracic Society, 2019. http://dx.doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a5494.

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Hoeing, K., S. Murray, S. Mujahid, et al. "Gamma Secretase in Type 2 Cells and Fibroblasts during Fetal Mouse Lung Development." In American Thoracic Society 2009 International Conference, May 15-20, 2009 • San Diego, California. American Thoracic Society, 2009. http://dx.doi.org/10.1164/ajrccm-conference.2009.179.1_meetingabstracts.a1951.

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Manlin Wu, Yuhao Chen, Haixia Fu, et al. "The novel mTOR inhibitor RAD001 (Eeverolimus) induces antiproliferative effects in goat fetal fibroblasts." In 2011 International Conference on Remote Sensing, Environment and Transportation Engineering (RSETE). IEEE, 2011. http://dx.doi.org/10.1109/rsete.2011.5964203.

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Lee, Matt K., Susan M. Smith, Sandy Murray, Lucia D. Pham, and Heber C. Nielsen. "Dihydrotestosterone Activates Src To Increase ErbB-1-Mediated Erk Activation In Fetal Lung Fibroblasts." In American Thoracic Society 2012 International Conference, May 18-23, 2012 • San Francisco, California. American Thoracic Society, 2012. http://dx.doi.org/10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a4944.

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Ignjatijević, Ana, Stefana Vuletić, Biljana Nikolić, et al. "EVALUATION OF ANTIGENOTOXIC POTENTIAL OF METHANOLIC AND DICHLOROMETHANE EXTRACTS OF Achillea millefolium." In 8th Workshop Food and Drug Safety and Qualit. Vinča Institute of Nuclear Sciences - National Institute of the Republic of Serbia, 2024. http://dx.doi.org/10.46793/8fdsq.pc3ai.

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Genotoxicity refers to the ability of various agents, called genotoxins, to induce damage to genetic material. Given their involvement in various human diseases, exploring new protective compounds from natural sources, especially plants, is of crucial importance today. With that in mind, our study evaluated the potential antigenotoxic effect of methanolic and dichloromethane extracts of traditionally used plant Achillea millefolium on normal fetal fibroblasts (MRC-5). The screening of cytotoxicity was conducted using an MTT assay to determine non-cytotoxic concentrations of extracts on MRC-5 c
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Chen, Yuhao, Haixia Fu, Bingchun Liu, Xinjie Cui, Xiao Wang, and Zhigang Wang. "RAD001 (everolimus) induces antiproliferative effect and abnormal cell morphology in goat fetal fibroblasts under optical microscope." In 2011 International Conference on Human Health and Biomedical Engineering (HHBE). IEEE, 2011. http://dx.doi.org/10.1109/hhbe.2011.6027941.

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Brockmeyer, T., R. Williams, AB Knoll, S. Murray, HC Nielsen, and CE Dammann. "Effects of Fetal Rat Lung Type II Cells and Fibroblasts on Bone Marrow Mesenchymal Stem Cell Behavior." In American Thoracic Society 2009 International Conference, May 15-20, 2009 • San Diego, California. American Thoracic Society, 2009. http://dx.doi.org/10.1164/ajrccm-conference.2009.179.1_meetingabstracts.a3275.

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Han, Lu, Yongxia Xu, Sean Sweeney, et al. "Abstract PR001: The splanchnic mesenchyme during fetal development is the major source of pancreatic cancer associated fibroblasts." In Abstracts: AACR Virtual Special Conference: The Evolving Tumor Microenvironment in Cancer Progression: Mechanisms and Emerging Therapeutic Opportunities; in association with the Tumor Microenvironment (TME) Working Group; January 11-12, 2021. American Association for Cancer Research, 2021. http://dx.doi.org/10.1158/1538-7445.tme21-pr001.

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Reports on the topic "Fetal Fibroblast"

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Lyutakov, Ivan, Radislav Nakov, Borislav Vladimirov, et al. Diagnostic Accuracy and Predictive Value of Serum Fibroblast Growth Factor 19 (FGF19) and Total Free Fecal Bile Acids as Biomarkers of Bile Acid Malabsorption in Patients with Chronic Diarrhea: a Pilot Study. "Prof. Marin Drinov" Publishing House of Bulgarian Academy of Sciences, 2020. http://dx.doi.org/10.7546/crabs.2020.12.16.

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