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Journal articles on the topic 'Human herpesvirus type 7'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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1

Pavel, A. Dyachenko. "Acute Human Herpesvirus-7-associated Encephalitis in a Young Adult Coinfected with Herpes Simplex Virus -1/2 and Epstein-Barr Virus." International Neuropsychiatric Disease Journal 9, no. 3 (2017): 1–5. https://doi.org/10.9734/INDJ/2017/34258.

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<strong>Background: </strong>Herpesvirus encephalitis (HVE) is a serious threat to people's health and life. The most common cause of these is herpes simplex virus. On the contrary, only isolated cases of encephalitis associated with herpesvirus type 7 are described. <strong>Objective: </strong>To describe a case of acute encephalitis in a young adult caused by uncommon Human herpesvirus 7 (HHV-7), underlying with Herpes simplex virus 1/2 (HSV-1/2) and Epstein-Barr virus (EBV) coinfection. <strong>Results: </strong>A 20-years-old woman presented to The Center of Infectious Disorders of the Ner

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Secchiero, Paola, Laura Davico Bonino, Paolo Lusso, et al. "Human herpesvirus type 7 in Hodgkin's disease." British Journal of Haematology 101, no. 3 (1998): 492–99. http://dx.doi.org/10.1046/j.1365-2141.1998.00718.x.

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Ashshi, A. "Detection of human cytomegalovirus, human herpesvirus type 6 and human herpesvirus type 7 in urine specimens by multiplex PCR." Journal of Infection 47, no. 1 (2003): 59–64. http://dx.doi.org/10.1016/s0163-4453(03)00057-4.

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Moravvej, H., E. Abolhasani, H. Rahimi, P. Alirezaei, M. Mahmoudi-Rad, and H. Keyvani. "Lichen planus is not associated with human herpesvirus type 7." British Journal of Dermatology 167, no. 4 (2012): 960–61. http://dx.doi.org/10.1111/j.1365-2133.2012.11009.x.

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Nazaryan, R. S., Yu V. Fomenko, N. A. Scheblykina, T. A. Kolesova, N. V. Golik, and E. V. Sukhostavets. "Herpesviruses. Part 1." Ukraïnsʹkij žurnal medicini, bìologìï ta sportu 5, no. 6 (2020): 299–307. http://dx.doi.org/10.26693/jmbs05.06.299.

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One of the urgent problems of modern medicine is the high incidence of herpesvirus infections. The high prevalence of herpesviruses in the human population of the world allow us to consider herpes a common systemic disease of the whole organism. Doctors of any specialty are faced with the clinical manifestations of herpes infection in patients, and they themselves are a risk group of chronic herpes infections formation due to constant patient contacts and frequent professional psycho-emotional overload. Herpes infections are a group of infectious diseases caused by human herpesviruses. Now it

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Kleshcheva, E. A., S. A. Kochergin, and Yu B. Slonimskiy. "Features of Diagnostics and Complex Approach to Therapy of Herpetic Keratitis." Ophthalmology in Russia 16, no. 2 (2019): 252–58. http://dx.doi.org/10.18008/1816-5095-2019-2-252-258.

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Objective. To determine the characteristics of drug therapy in patients with herpetic keratitis (HK), based on laboratory diagnosis.Material and methods. 49 patients with clinical symptoms of HK were included in the study. The conjunctival cells were used as a material for laboratory diagnosis of adenovirus and enterovirus infection by polymerase chain reaction (PCR) and for microbiological examination. Herpesvirus DNA in tears, saliva, urine and blood was determined using PCR (for varicella-zoster virus (VZV) and human herpesvirus type 7 (HHV-7)) and real-time PCR (for herpes simplex virus ty

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Zhang, Ying, Leen de Bolle, Stefano Aquaro, Alfons van Lommel, Erik De Clercq, and Dominique Schols. "Productive Infection of Primary Macrophages with Human Herpesvirus 7." Journal of Virology 75, no. 21 (2001): 10511–14. http://dx.doi.org/10.1128/jvi.75.21.10511-10514.2001.

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ABSTRACT Here we demonstrate replication of human herpesvirus 7 (HHV-7), a T-lymphotropic virus, in macrophages. Productive replication was lost after 2 weeks, but HHV-7 DNA was detected up to 1 month after infection. Thus, macrophages become infected by HHV-7 and might play an important role as a viral reservoir, as has been demonstrated for human immunodeficiency virus type 1.

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Nikolskiy, Mikhail A., L. B. Kulyashova, A. V. Zakrevskaya, D. A. Lioznov, T. A. Kaptur, and M. A. Zolotova. "THE DETECTION OF IGG TO HUMAN HERPESVIRUS TYPE 7 IN CHILDREN." Epidemiology and Infectious Diseases (Russian Journal) 23, no. 2 (2018): 89–92. http://dx.doi.org/10.18821/1560-9529-2018-23-2-89-92.

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Background. There are no data on HHV-7 seroprevalence in Russia. Previously we detected HHV-7 DNA in plasma of 8-10% children with exanthem subitum and fever without rash. Aim. To perform the comparative study of the seroprevalence of HHV-7 and HHV-6 in children in Russia. Materials and methods. The pilot study included 116 children, aged from 10 days to 10 years. Serum samples were tested for IgG to HHV-7 and HHV-6 by indirect immunofluorescent assays and ELISA correspondingly. Results. The prevalence rate antibodies to HHV-7 was three times lower than for antibodies to HHV-6. There were only

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Melón, S., M. de Oña, M. E. Alvarez-Argüelles, et al. "67: Human herpesvirus type 6 and 7 in central nervous system." Journal of Clinical Virology 37 (December 2006): S115. http://dx.doi.org/10.1016/s1386-6532(06)70086-5.

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Lin, Liang-Yu, Ketaki Bhate, Harriet Forbes, Liam Smeeth, Charlotte Warren-Gash, and Sinéad Langan. "Vitamin D deficiency or supplementation and the risk of human herpesvirus infections or reactivation: a systematic review protocol." BMJ Open 9, no. 10 (2019): e031867. http://dx.doi.org/10.1136/bmjopen-2019-031867.

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IntroductionHuman herpesviruses induce lifelong latent infections and may reactivate as the immune system deteriorates. Recent studies have suggested that vitamin D, an essential element of bone health, may have some effect of protecting against infections, but investigations of its potential to prevent herpesvirus infection or reactivation are limited. We will review the current literature examining vitamin D and the risk of herpesvirus infections or reactivation.Methods and analysisOur systematic review will address two research questions: (1) Do deficient/insufficient serum vitamin D levels

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Wilborn, F., C. A. Schmidt, F. Lorenz, et al. "Human herpesvirus type 7 in blood donors: Detection by the polymerase chain reaction." Journal of Medical Virology 47, no. 1 (1995): 65–69. http://dx.doi.org/10.1002/jmv.1890470113.

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de Oña, M., S. Melón, J. L. Rodriguez, J. C. Sanmartin, and M. J. Bernardo. "Association between human herpesvirus type 6 and type 7, and cytomegalovirus disease in heart transplant recipients." Transplantation Proceedings 34, no. 1 (2002): 75–76. http://dx.doi.org/10.1016/s0041-1345(01)02672-0.

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Zumo, L., and R. P. Grewal. "Castleman's disease-associated neuropathy: no evidence of human herpesvirus type 8 infection." Journal of the Neurological Sciences 195, no. 1 (2002): 47–50. http://dx.doi.org/10.1016/s0022-510x(01)00679-7.

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Lisco, Andrea, Jean-Charles Grivel, Angélique Biancotto, et al. "Viral Interactions in Human Lymphoid Tissue: Human Herpesvirus 7 Suppresses the Replication of CCR5-Tropic Human Immunodeficiency Virus Type 1 via CD4 Modulation." Journal of Virology 81, no. 2 (2006): 708–17. http://dx.doi.org/10.1128/jvi.01367-06.

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ABSTRACT Human immunodeficiency virus (HIV) infection is often accompanied by infection with other pathogens that affect the clinical course of HIV disease. Here, we identified another virus, human herpesvirus 7 (HHV-7) that interferes with HIV type 1 (HIV-1) replication in human lymphoid tissue, where critical events of HIV disease occur. Like the closely related HHV-6, HHV-7 suppresses the replication of CCR5-tropic (R5) HIV-1 in coinfected blocks of human lymphoid tissue. Unlike HHV-6, which affects HIV-1 by upregulating RANTES, HHV-7 did not upregulate any CCR5-binding chemokine. Rather, t

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Mendez, J. C., G. W. Procop, M. J. Espy, C. V. Paya, and T. F. Smith. "Detection and Semiquantitative Analysis of Human Herpesvirus 8 DNA in Specimens from Patients with Kaposi’s Sarcoma." Journal of Clinical Microbiology 36, no. 8 (1998): 2220–22. http://dx.doi.org/10.1128/jcm.36.8.2220-2222.1998.

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Kaposi’s sarcoma (KS) is the most common neoplasm in patients with AIDS. Epidemiologic evidence and the recent identification of herpesvirus-like DNA sequences in patients with KS have suggested a role for viral agents in the etiopathogenesis of this disease. It is unclear if these sequences are present in all types of KS and if the copy number of these sequences has a correlation with disease severity (staging). In order to clarify these issues, we retrospectively analyzed, by PCR and Southern blotting, formalin-fixed, paraffin-embedded biopsy specimens from 12 patients previously diagnosed w

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VITALE, F., E. VIVIANO, A. M. PERNA, et al. "Serological and virological evidence of non-sexual transmission of human herpesvirus type 8 (HHV8)." Epidemiology and Infection 125, no. 3 (2000): 671–75. http://dx.doi.org/10.1017/s0950268800004726.

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To evaluate whether or not human herpesvirus 8 (HHV8) can be transmitted through a non-sexual route a serological survey was carried out in a group of 51 catholic nuns. The seroprevalence rate and the geometrical mean antibody titre to anti-latent HHV8 antigen were similar in nuns and in a group of 60 women, matched by age, in the general population (27 vs. 24%; 1028 vs. 1575, respectively). Moreover, by using nested polymerase chain reaction (PCR), HHV8 DNA sequences were detected in 7 of 16 (43·8%) saliva and peripheral blood mononuclear cells (PBMC) from patients with classical Kaposi's sar

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Zhen, Yuan-Yuan, Jing Yang, and Pei-Yuan Liao. "Human herpesvirus 7 meningitis in an adolescent with normal immune function: A case report." World Journal of Clinical Cases 12, no. 18 (2024): 3636–43. http://dx.doi.org/10.12998/wjcc.v12.i18.3636.

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BACKGROUND Human herpesvirus type 7 (HHV-7) is a less common herpes virus that usually causes mild, self-limiting illnesses. However, in recent years, there have been increasing reports of HHV-7 causing serious central nervous system infections, especially meningitis. The pathogenesis and clinical features of HHV-7 meningitis, particularly in adolescents with normal immune function, remain incompletely studied. Therefore, the purpose of this report is to share a case of HHV-7 meningitis in an immunocompetent adolescent with a view to deepening our understanding of the disease. CASE SUMMARY A 1

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De Vries, H. J. C., J. Van Marle, M. B. M. Teunissen, et al. "Lichen planus is associated with human herpesvirus type 7 replication and infiltration of plasmacytoid dendritic cells." British Journal of Dermatology 154, no. 2 (2005): 361–64. http://dx.doi.org/10.1111/j.1365-2133.2005.06999.x.

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van den Berg, J. S. P., J. H. van Zeijl, J. J. Rotteveel, W. J. G. Melchers, F. J. M. Gabreels, and J. M. D. Galama. "Neuroinvasion by human herpesvirus type 7 in a case of exanthem subitum with severe neurologic manifestations." Neurology 52, no. 5 (1999): 1077. http://dx.doi.org/10.1212/wnl.52.5.1077.

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Dyachenko, P. A., and A. G. Dyachenko. "CREUTZFELDT-JAKOB DISEASE IN MAN CO-INFECTED WITH SARS-COV-2-VIRUS, AND HUMAN HERPESVIRUS TYPE 7." Preventive medicine. Theory and practice 4, no. 4 (2023): 41–43. http://dx.doi.org/10.61948/prevmed-2023-4-41.

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21

Tomaszewska, Agnieszka, Anna Kryśko, Tomasz Dzieciątkowski, et al. "Co-Infections with Cytomegalovirus and Human Herpesvirus Type 7 in Adult Polish Allogeneic Haematopoietic Stem Cell Transplant Recipients." Archivum Immunologiae et Therapiae Experimentalis 62, no. 1 (2013): 77–80. http://dx.doi.org/10.1007/s00005-013-0252-z.

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22

Thomsen, Darrell R., Nancee L. Oien, Todd A. Hopkins, et al. "Amino Acid Changes within Conserved Region III of the Herpes Simplex Virus and Human Cytomegalovirus DNA Polymerases Confer Resistance to 4-Oxo-Dihydroquinolines, a Novel Class of Herpesvirus Antiviral Agents." Journal of Virology 77, no. 3 (2003): 1868–76. http://dx.doi.org/10.1128/jvi.77.3.1868-1876.2003.

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ABSTRACT The 4-oxo-dihydroquinolines (PNU-182171 and PNU-183792) are nonnucleoside inhibitors of herpesvirus polymerases (R. J. Brideau et al., Antiviral Res. 54:19-28, 2002; N. L. Oien et al., Antimicrob. Agents Chemother. 46:724-730, 2002). In cell culture these compounds inhibit herpes simplex virus type 1 (HSV-1), HSV-2, human cytomegalovirus (HCMV), varicella-zoster virus (VZV), and human herpesvirus 8 (HHV-8) replication. HSV-1 and HSV-2 mutants resistant to these drugs were isolated and the resistance mutation was mapped to the DNA polymerase gene. Drug resistance correlated with a poin

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Jang, Yoonhyuk, Jeong-Min Kim, Jangsup Moon, et al. "Anti-N-methyl-D-aspartate receptor encephalitis 8 years after serial herpes simplex virus type 1 and human herpesvirus type 7 encephalitis." encephalitis 1, no. 1 (2020): 25–29. http://dx.doi.org/10.47936/encephalitis.2020.00066.

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Kimura, Hirokazu, Yuriko Hayashi, Masanari Kitagawa, et al. "Pathogen Profiles in Outpatients with Non-COVID-19 during the 7th Prevalent Period of COVID-19 in Gunma, Japan." Microorganisms 11, no. 9 (2023): 2142. http://dx.doi.org/10.3390/microorganisms11092142.

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The identification of pathogens associated with respiratory symptoms other than the novel coronavirus disease 2019 (COVID-19) can be challenging. However, the diagnosis of pathogens is crucial for assessing the clinical outcome of patients. We comprehensively profiled pathogens causing non-COVID-19 respiratory symptoms during the 7th prevalent period in Gunma, Japan, using deep sequencing combined with a next-generation sequencer (NGS) and advanced bioinformatics technologies. The study included nasopharyngeal swabs from 40 patients who tested negative for severe acute respiratory syndrome cor

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Mardanly, Seifaddin Gashimovich, V. A. Arsenyeva, A. S. Avdonina, E. A. Amelina, and S. S. Mardanly. "FIRST RESULTS OF APPLICATION OF AN ENZYME IMMUNOASSAY IN THE SEROLOGICAL DIAGNOSTICS OF INFECTION CAUSED BY HERPESVIRUS TYPE 7." Russian Clinical Laboratory Diagnostics 64, no. 9 (2019): 530–35. http://dx.doi.org/10.18821/0869-2084-2019-64-9-530-535.

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HHV-7 (Human Herpes virus type 7) is a relatively recently discovered, ubiquitous beta herpes virus. In Russia, the diagnosis of HHV-7 infection is carried out by PCR, which determines the DNA in serum or plasma, if there are clinical indications. Laboratory serological tests for HHV-7 are not performed. Currently, in the scientific literature, information on clinical studies of HHV-7 infection, its epidemiology, and its role in the etiopathogenesis of various diseases is insufficient. This article presents the results of the development of a test kit “ELISA-HHV-7-IgG”, designed to detect spec

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Bélec, Laurent, Ali Si Mohamed, François-Jerôme Authier, et al. "Human Herpesvirus 8 Infection in Patients With POEMS Syndrome–Associated Multicentric Castleman’s Disease." Blood 93, no. 11 (1999): 3643–53. http://dx.doi.org/10.1182/blood.v93.11.3643.

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Abstract The polyneuropathy, organomegaly, endocrinopathy, M protein, skin changes (POEMS) syndrome is a rare multisystemic disorder associated with osteosclerotic myeloma and multicentric Castleman’s disease (MCD). Human herpesvirus type 8 (HHV-8) DNA sequences have been detected in lymph nodes of about 40% of human immunodeficiency virus (HIV)-negative patients with MCD, and in bone marrow stromal cells of patients with multiple myeloma. Considering these data, we investigated the presence of HHV-8 in 18 patients with POEMS syndrome (9 with MCD), by nested polymerase chain reaction (N-PCR) t

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Bélec, Laurent, Ali Si Mohamed, François-Jerôme Authier, et al. "Human Herpesvirus 8 Infection in Patients With POEMS Syndrome–Associated Multicentric Castleman’s Disease." Blood 93, no. 11 (1999): 3643–53. http://dx.doi.org/10.1182/blood.v93.11.3643.411k38_3643_3653.

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The polyneuropathy, organomegaly, endocrinopathy, M protein, skin changes (POEMS) syndrome is a rare multisystemic disorder associated with osteosclerotic myeloma and multicentric Castleman’s disease (MCD). Human herpesvirus type 8 (HHV-8) DNA sequences have been detected in lymph nodes of about 40% of human immunodeficiency virus (HIV)-negative patients with MCD, and in bone marrow stromal cells of patients with multiple myeloma. Considering these data, we investigated the presence of HHV-8 in 18 patients with POEMS syndrome (9 with MCD), by nested polymerase chain reaction (N-PCR) to detect

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Zhang, Ying, Sigrid Hatse, Erik De Clercq, and Dominique Schols. "CXC-Chemokine Receptor 4 Is Not a Coreceptor for Human Herpesvirus 7 Entry into CD4+ T Cells." Journal of Virology 74, no. 4 (2000): 2011–16. http://dx.doi.org/10.1128/jvi.74.4.2011-2016.2000.

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ABSTRACT Human herpesvirus 7 (HHV-7) is a T-lymphotropic virus which utilizes the CD4 receptor as its main receptor to enter the target cells. Hence, HHV-7 can interfere with human immunodeficiency virus type 1 (HIV-1) infection in CD4+ T cells. It was recently suggested that the CXC chemokine receptor 4 (CXCR4), which was found to be a crucial coreceptor for T-tropic HIV-1 strains, may also play a role in the HHV-7 infection process. However, the results presented here demonstrate that CXCR4 is not involved in HHV-7 infection. The natural ligand of CXCR4, SDF-1α, was not able to inhibit HHV-7

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Fatkullina, G. R., V. A. Anokhin, and A. R. Musina. "Human Herpes virus 7 infections in children. Clinical and laboratory aspects." Journal Infectology 12, no. 5 (2021): 114–22. http://dx.doi.org/10.22625/2072-6732-2020-12-5-114-122.

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Objective: to study the activity of HSV 1,2, EBV, CMV, HHV6, HHV7 in children of different age groups, to determine the frequency of various symptoms and syndromes in the examined children depending on hhv7 monoinfection and combined herpetic infection in the age aspect.Materials and methods: 56 children aged 2 to 18 years were examined at the state MEDICAL research Institute named after Prof. A. F. Agafonov in Kazan, at the BIOMED medical and diagnostic center in Kazan and at the LUCH children’s clinic in Naberezhnye Chelny (boys accounted for 62.5% of cases, girls-37.5%). Verification of the

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Witvrouw, M., D. Daelemans, C. Pannecouque, et al. "Broad-Spectrum Antiviral Activity and Mechanism of Antiviral Action of the Fluoroquinolone Derivative K-12." Antiviral Chemistry and Chemotherapy 9, no. 5 (1998): 403–11. http://dx.doi.org/10.1177/095632029800900504.

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The fluoroquinolone derivatives have been shown to inhibit human immunodeficiency virus (HIV) replication at the transcriptional level. We confirmed the anti-HIV activity of the most potent congener, 8-difluoromethoxy-1-ethyl-6-fluoro-1,4-dihydro-7-[4-(2-methoxyphenyl)-1-piperazinyl]-4-quinolone-3-carboxylic acid (K-12), in both acutely and chronically infected cells. K-12 was active against different strains of HIV-1 (including AZT-and ritonavir-resistant HIV-1 strains), HIV-2 and simian immunodeficiency virus, in MT-4, CEM, C8166 and peripheral blood mononuclear cells. In all of these antivi

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Krynskiy, S. A., I. K. Malashenkova, D. P. Ogurtsov, et al. "Herpesvirus infections and immunological disturbances in patients with different stages of Alzheimer’s disease." Problems of Virology 66, no. 2 (2021): 129–39. http://dx.doi.org/10.36233/0507-4088-32.

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Introduction. Alzheimer’s disease (AD) is a multifactorial disease that leads to a progressive memory loss, visualspatial impairments, emotional and personality changes. As its earliest pre-dementia clinical stage, amnestic mild cognitive impairment syndrome (aMCI) is currently considered. Neuroinflammation plays a role in the development and progression of aMCI and the initial stage of AD, which can be supported by immunological disorders of a systemic character. Study of factors, including infections, influencing immune disorders and systemic inflammatory response in patients with aMCI, is o

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Krug, Laurie T., Naoki Inoue, and Philip E. Pellett. "Sequence Requirements for Interaction of Human Herpesvirus 7 Origin Binding Protein with the Origin of Lytic Replication." Journal of Virology 75, no. 8 (2001): 3925–36. http://dx.doi.org/10.1128/jvi.75.8.3925-3936.2001.

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ABSTRACT As do human herpesvirus 6 variants A and B (HHV-6A and -6B), HHV-7 encodes a homolog of the alphaherpesvirus origin binding protein (OBP), which binds at sites in the origin of lytic replication (oriLyt) to initiate DNA replication. In this study, we sought to characterize the interaction of the HHV-7 OBP (OBPH7) with its cognate sites in the 600-bp HHV-7oriLyt. We expressed the carboxyl-terminal domain of OBPH7 and found that amino acids 484 to 787 of OBPH7 were sufficient for DNA binding activity by electrophoretic mobility shift analysis. OBPH7 has one high-affinity binding site (O

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Isakov, D. V. "Innovative approaches to treatment of human herpesvirus infections during the COVID-19 pandemic." Infekcionnye bolezni 21, no. 2 (2023): 95–103. http://dx.doi.org/10.20953/1729-9225-2023-1-95-103.

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During lifetime the human body is constantly in contact with various microorganisms, which can be either harmless and/or beneficial, or can cause various infectious diseases. Acute respiratory viral infections (ARVI) are the most common among them: according to the official report “The 2020 Status of Sanitary and Epidemiological Population Well-being in the Russian Federation” the economic cost of ARVI of multiple and unspecified localization was quite substantial, amounting to 606,505,442.0 roubles. The main causative agents of ARVI are influenza viruses type A and B, respiratory syncytial vi

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Ahmed, Waqar, Pretty S. Philip, Samir Attoub, and Gulfaraz Khan. "Epstein–Barr virus-infected cells release Fas ligand in exosomal fractions and induce apoptosis in recipient cells via the extrinsic pathway." Journal of General Virology 96, no. 12 (2015): 3646–59. http://dx.doi.org/10.1099/jgv.0.000313.

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Epstein–Barr virus (EBV; human herpesvirus 4) is an oncogenic herpesvirus implicated in the pathogenesis of several human malignancies. A number of recent studies indicate that EBV can manipulate the local microenvironment by excreting viral and cellular components in nanovesicles called exosomes. In this study, we investigated the impact of EBV-derived exosomes on apoptosis of recipient cells and the molecular pathway involved in this process. Exosomes from EBV-infected but not from non-infected cells induced apoptosis in a number of different cell types, including B-cells, T-cells and epithe

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Altay-Kocak, Aylin, Gulendam Bozdayi, Janine Michel, et al. "Multi-assay investigation of viral etiology in pediatric central nervous system infections." Journal of Infection in Developing Countries 14, no. 06 (2020): 572–79. http://dx.doi.org/10.3855/jidc.12327.

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Introduction: In an attempt to identify a wide spectrum of viral infections, cerebrospinal fluid (CSF) specimens were collected from pediatric cases with the preliminary diagnosis of viral encephalitis/meningoencephalitis in two reference hospitals, from October 2011 to December 2015. Methodology: A combination of nucleic acid-based assays, including in house generic polymerase chain reaction (PCR) assays for enteroviruses, flaviviruses and phleboviruses, a commercial real-time PCR assay for herpesviruses and a commercial real time multiplex PCR, enabling detection of frequently-observed

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Neroev, V. V., L. A. Katargina, L. A. Kovaleva, G. I. Krichevskaya, and N. V. Balatskaya. "Clinical Aspects of Bacterial Corneal Ulcer Prolonged Course, the Role of Herpes Viruses in Its Pathogenesis, Treatment." Ophthalmology in Russia 16, no. 1S (2019): 40–44. http://dx.doi.org/10.18008/1816-5095-2019-1s-40-44.

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Purpose: to study the role of human herpesviruses (HHV) in the pathogenesis of prolonged bacterial corneal ulcers. Patients and methods. 117 patients with bacterial corneal ulcer were examined. Two groups were identified: a favorable course-with duration of bacterial corneal ulcer epithelialization for 17 days (62 people) and a prolonged course with a persistent ulcer more than 17 days (55 people). Blood samples (n = 117) and scrapes from corneal ulcer (n = 117) were investigated in polymerase chain reaction (PCR) for the presence of deoxyribonucleic acid (DNA) of Herpes simplex virus (HSV1, 2

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Aline BAMIA, Marie Danielle ABILA AFOUDA, Josiane Kikie ESSOLA, and Dieudonné Désiré ADIOGO. "Seroprevalence of human herpesvirus type 8 (HHV-8) in blood donors at Laquintinie Hospital of Douala (LHD), Cameroon." International Journal of Science and Research Archive 9, no. 1 (2023): 449–54. http://dx.doi.org/10.30574/ijsra.2023.9.1.0454.

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Background: The Human Herpesvirus type 8 (HHV-8), also called Kaposi sarcoma-associated herpesvirus (KSHV) is an oncogenic virus. Its prevalence is high in many sub-Saharan African countries and some Asian areas. HHV-8 is transmitted through saliva and is acquired in early childhood. HHV-8 can also be transmitted sexually and by organ transplant or blood transfusion. Cameroon is an endemic area. That is why, for improving transfusion safety purpose, we assessed the HHV-8 infection rate in blood donors since the risk of transmission by blood transfusion was shown. Material and methods: Blood sa

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Peremot, SD, LA Suhanova, MV Smilyanska, NV Kashpur, and AO Chernogrebel. "Combination of pulmonary tuberculosis and herpetic infection children." Annals of Mechnikov Institute, no. 3 (September 10, 2021): 17–20. https://doi.org/10.5281/zenodo.5499597.

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<strong>Introduction.</strong> The WHO estimates that millions of children become infected with Mycobacterium tuberculosis each year, and more than a million develop tuberculosis (TB). Most children are able to immunologically contain or neutralize the pathogen without developing pathology. Our country ranks 4th in the world in the incidence of adult tuberculosis, and fifth in the incidence of children among 53 regions controlled by the WHO European Office. The average estimated incidence of children in Ukraine is 37.4 per 100 thousand children, and exceeds the official figure by 4.5 times. <s

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Ferreira Menoni, Silvia Mendonça, Lucas Lopes Leon, Rodrigo Gonçalves de Lima, et al. "Characterization of Herpesviridae Family Members, BK Virus, and Adenovirus in Children and Adolescents with Nephrotic Syndrome." Viruses 16, no. 7 (2024): 1017. http://dx.doi.org/10.3390/v16071017.

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Since the significance of viral infections in children and adolescents with nephrotic syndrome (NS) is yet to be defined, this study intended to estimate the occurrence, pattern, and outcomes of some DNA viral infections in children with NS. Methods: A prospective study was conducted to determine the genome identification of the viruses Epstein-Barr (EBV), human cytomegalovirus (HCMV), human herpesvirus 6 (HHV-6 type A and type B) and 7 (HHV-7), polyomavirus (BKV), and human adenovirus (HAdV) in plasma and urine samples of pediatric patients with NS. Results: A total of 35 patients aged 1 to 1

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Leite, Janaina Luisa, Natassia Elena Bufalo, Roberto Bernardo Santos, João Hamilton Romaldini, and Laura Sterian Ward. "Herpesvirus type 7 infection may play an important role in individuals with a genetic profile of susceptibility to Graves' disease." European Journal of Endocrinology 162, no. 2 (2010): 315–21. http://dx.doi.org/10.1530/eje-09-0719.

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ObjectiveAn inherited profile of genes related to the response to aggressive environmental factors such as viruses and chemicals may be related to an increased susceptibility to Graves' disease (GD).Design and methodsThis prospective case–control study was designed to examine the relationship between human herpesviruses (HHV) infection, determined by circulating DNA; tumour protein p53 (TP53) apoptotic ability; and detoxification system genes, and GD. We studied 280 confirmed GD patients paired to 284 controls with respect to environmental exposure. Exclusion criteria included medications that

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Wilborn, F., V. Brinkmann, CA Schmidt, F. Neipel, H. Gelderblom, and W. Siegert. "Herpesvirus type 6 in patients undergoing bone marrow transplantation: serologic features and detection by polymerase chain reaction." Blood 83, no. 10 (1994): 3052–58. http://dx.doi.org/10.1182/blood.v83.10.3052.3052.

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Abstract To evaluate the potential role of human herpesvirus type 6 (HHV-6) infection in patients after bone marrow transplantation (BMT) we sequentially analyzed buffy coat leukocytes, oral lavage fluid, and urine from 57 patients for the presence of HHV-6 DNA by polymerase chain reaction (PCR) before and after 60 BMTs. Twenty-four patients undergoing autologous BMT and 36 with allogeneic BMT were studied. Thirty-six patients (60%) were PCR positive in one or more tests. The majority of PCR-positive patients had positive results only sporadically, in 1 (n = 23) or 2 weeks (n = 5). Six patient

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Haque, Muzammel, Jiguo Chen, Keiji Ueda, et al. "Identification and Analysis of the K5 Gene of Kaposi's Sarcoma-Associated Herpesvirus." Journal of Virology 74, no. 6 (2000): 2867–75. http://dx.doi.org/10.1128/jvi.74.6.2867-2875.2000.

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ABSTRACT Kaposi's sarcoma-associated herpesvirus (KSHV), or human herpesvirus 8 (HHV-8), belongs to the gammaherpesvirus subfamily and encodes ∼80 open reading frames (ORFs). Among them are a few candidates for immediate-early genes (e.g., K5). We developed a monoclonal antibody (MAb), 328C7, against the K5 antigen. This MAb reacted with the K5 gene product by immunoscreening of a cDNA library from BCBL-1 cells, and this result was confirmed by transfection of the K5 ORF into Cos-7 cells. After induction of lytic infection by treatment with 12-O-tetradecanoylphorbol-13-acetate, MAb 328C7 react

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Melekhina, E. V., D. V. Preobrazhenskaia, A. D. Muzyka, E. Yu Soldatova, and A. V. Gorelov. "Recurrent respiratory infections and active herpesvirus infections in children: problems and solutions." Russian Medical Inquiry 7, no. 11 (2023): 704–12. http://dx.doi.org/10.32364/2587-6821-2023-7-11-2.

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Background: recurrent respiratory infections (RRI) in children are a relevant medical and social issue. Reactivation of latent herpes simplex virus (HSV) infections is recognized as one of the leading causes of recurrent respiratory infections. Its rate in children is up to 40%. Therapeutic options for recurrent respiratory infections in children are discussed given the activity of HSV infections and immune disorder treatment. Aim: to assess the efficacy of inosine pranobex (Normomed®) for recurrent respiratory infections and active HSV infection in children. Patients and Methods: we examined

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Martins, Fabiana, Debora Pallos, Jodkandlys Candeia, Rodrigo Zerbinati, Paulo Henrique Braz-Silva, and Luana Campos. "Noninvasive Techniques for Management of Erythema Multiforme." Case Reports in Dentistry 2023 (December 19, 2023): 1–4. http://dx.doi.org/10.1155/2023/9938939.

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An 18-year-old man was referred for a diagnosis of extensive oral lesions. During the interview, he reported a medical history of ganglionic tuberculosis, type 2 herpes infection, and significant weight loss due to dysphagia. Intraoral exam revealed multiple painful and ulcerated lesions covered by pseudomembrane. Lesions were observed on the labial and buccal mucosa, tongue, and soft palate. The laboratory findings included serum positivity for the Epstein-Barr virus, and salivary tests showed positive values for herpes simplex virus (HSV-2) and human herpesvirus (HHV-7). The diagnostic hypot

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Blay, Martin, Michael Weiss, Gundula Jäger, and Annette Pohl-Koppe. "Detection of Human Herpesvirus Type 7 (Hhv7) in the Cerebrospinal Fluid(Csf) of Children With Aseptic Meningitis/Encephalitis and Other Central Nervous System Diseases By Polymerase Chain Reaction (Pcr)." Pediatric Research 44, no. 3 (1998): 429. http://dx.doi.org/10.1203/00006450-199809000-00094.

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Górka, Kamila, Marcin Koleśnik, Kinga Salwa, Mateusz Kwaśnik, and Konrad Kubiński. "Evaluation of Antibacterial, Antifungal, Antiviral, and Anticancer Potential of Extract from the Fern Dryopteris erythrosora." International Journal of Molecular Sciences 26, no. 11 (2025): 5182. https://doi.org/10.3390/ijms26115182.

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Plant extracts are increasingly being investigated due to their high content of pharmacologically active substances. The primary focus is placed on angiosperms, while pteridophytes are less popular, although their medicinal properties have been recognized for centuries. In this study, we uncover some biological properties of the extract from Dryopteris erythrosora (DEE), a fern traditionally used for liver treatment in Asia, which has not been widely explored in this context before. This study involved the determination of the total content of polyphenols and flavonoids as well as the evaluati

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Oikonomou, Katerina G., and Sarah Taimur. "Non-CMV Viral Infections Following Solid-Organ Transplantation – Focus on Human T-Cell Lymphotropic Virus Type-1 and Human Herpesviruses-6,-7 and -8." OBM Transplantation 3, no. 2 (2019): 1. http://dx.doi.org/10.21926/obm.transplant.1902066.

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Kraus, Richard J., Sarah J. Mirocha, Heather M. Stephany, Joel R. Puchalski, and Janet E. Mertz. "Identification of a Novel Element Involved in Regulation of the Lytic Switch BZLF1 Gene Promoter of Epstein-Barr Virus." Journal of Virology 75, no. 2 (2001): 867–77. http://dx.doi.org/10.1128/jvi.75.2.867-877.2001.

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ABSTRACT Epstein-Barr virus (EBV) is a human herpesvirus capable of establishing a latent state in B lymphocytes. EBV's BZLF1 gene product plays a central role in regulating the switch from latency to productive infection. Here, we identify a sequence element, 5′-CAGGTA-3′, called ZV, located at nucleotides −17 to −12 relative to the transcription initiation site of the BZLF1 promoter. ZV sequence-specifically binds a cellular nuclear factor(s), ZVR. ZVR DNA-binding activity was present in the EBV-negative B-lymphocytic cell line DG75, the EBV-positive B-lymphocytic cell lines GG68 and 721, th

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Greco, Raffaella, Francesca Lorentino, Lara Crucitti, et al. "Human Herpes Virus 6 Reactivation and Disease After Allogeneic Hematopoietic Stem Cell Transplantation." Blood 122, no. 21 (2013): 4539. http://dx.doi.org/10.1182/blood.v122.21.4539.4539.

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Background Human herpesvirus type 6 (HHV-6) is a member of the beta herpesvirus subfamily (genus Roseolovirus) and two distinct variants have been described: types A and B. HHV-6 infection is recognized as the cause of a febrile disease and exanthem subitum in early childhood. The infection rarely causes serious events in healthy individuals, but viral reactivation in immunocompromised patients is frequently associated with severe clinical manifestations. Above all HHV-6 is increasingly recognized as an opportunistic and potentially life-threatening pathogen in recipients of allogeneic hematop

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Lucht, Erik, Maria Brytting, Lotte Bjerregaard, Inger Julander, and Annika Linde. "Shedding of Cytomegalovirus and Herpesviruses 6, 7, and 8 in Saliva of Human Immunodeficiency Virus Type 1–Infected Patients and Healthy Controls." Clinical Infectious Diseases 27, no. 1 (1998): 137–41. http://dx.doi.org/10.1086/514604.

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