Log in

Relevant bibliographies by topics / Human platelet

Contents

Journal articles
Dissertations / Theses
Books
Book chapters
Conference papers
Reports

Academic literature on the topic 'Human platelet'

Author: Grafiati

Published: 21 February 2023

Last updated: 25 July 2025

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the lists of relevant articles, books, theses, conference reports, and other scholarly sources on the topic 'Human platelet.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Journal articles on the topic "Human platelet"

1

POLGÁR, János, Ruth M. KRAMER, Suzane L. UM, Joseph A. JAKUBOWSKI, and Kenneth J. CLEMETSON. "Human group II 14 kDa phospholipase A2 activates human platelets." Biochemical Journal 327, no. 1 (1997): 259–65. http://dx.doi.org/10.1042/bj3270259.

Full text

Abstract:

Recombinant human group II phospholipase A2 (sPLA2) added to human platelets in the low μg/ml range induced platelet activation, as demonstrated by measurement of platelet aggregation, thromboxane A2 generation and influx of intracellular free Ca2+ concentration and by detection of time-dependent tyrosine phosphorylation of platelet proteins. The presence of Ca2+ at low millimolar concentrations is a prerequisite for the activation of platelets by sPLA2. Mg2+ cannot replace Ca2+. Mg2+, given in addition to the necessary Ca2+, inhibits sPLA2-induced platelet activation. Pre-exposure to sPLA2 co

APA, Harvard, Vancouver, ISO, and other styles

2

Coxon, Carmen H., Alexander M. Lewis, Amanda J. Sadler, et al. "NAADP regulates human platelet function." Biochemical Journal 441, no. 1 (2011): 435–42. http://dx.doi.org/10.1042/bj20111175.

Full text

Abstract:

Platelets play a vital role in maintaining haemostasis. Human platelet activation depends on Ca2+ release, leading to cell activation, granule secretion and aggregation. NAADP (nicotinic acid–adenine dinucleotide phosphate) is a Ca2+-releasing second messenger that acts on acidic Ca2+ stores and is used by a number of mammalian systems. In human platelets, NAADP has been shown to release Ca2+ in permeabilized human platelets and contribute to thrombin-mediated platelet activation. In the present study, we have further characterized NAADP-mediated Ca2+ release in human platelets in response to

APA, Harvard, Vancouver, ISO, and other styles

3

Krisch, Linda, Gabriele Brachtl, Sarah Hochmann, et al. "Improving Human Induced Pluripotent Stem Cell-Derived Megakaryocyte Differentiation and Platelet Production." International Journal of Molecular Sciences 22, no. 15 (2021): 8224. http://dx.doi.org/10.3390/ijms22158224.

Full text

Abstract:

Several protocols exist for generating megakaryocytes (MKs) and platelets from human induced pluripotent stem cells (hiPSCs) with limited efficiency. We observed previously that mesoderm induction improved endothelial and stromal differentiation. We, therefore, hypothesized that a protocol modification prior to hemogenic endothelial cell (HEC) differentiation will improve MK progenitor (MKP) production and increase platelet output. We further asked if basic media composition affects MK maturation. In an iterative process, we first compared two HEC induction protocols. We found significantly mo

APA, Harvard, Vancouver, ISO, and other styles

4

Kelm, RJ Jr, and KG Mann. "Human platelet osteonectin: release, surface expression, and partial characterization." Blood 75, no. 5 (1990): 1105–13. http://dx.doi.org/10.1182/blood.v75.5.1105.1105.

Full text

Abstract:

Abstract Our laboratory has previously shown that osteonectin, an abundant noncollagenous bone protein, is contained in and secreted from human platelets. In this study, the distribution of osteonectin both in the supernatant and on the platelet surface after activation was measured by fluid-phase and solid-phase radioimmunoassay, respectively. Total cellular osteonectin was determined by RIA of guanidinium chloride extracted platelets and ranged from 0.65 to 2.2 micrograms/10(8) platelets or 135,000 to 457,000 molecules/platelet. Platelets treated with varying concentrations of collagen and t

APA, Harvard, Vancouver, ISO, and other styles

5

Kelm, RJ Jr, and KG Mann. "Human platelet osteonectin: release, surface expression, and partial characterization." Blood 75, no. 5 (1990): 1105–13. http://dx.doi.org/10.1182/blood.v75.5.1105.bloodjournal7551105.

Full text

Abstract:

Our laboratory has previously shown that osteonectin, an abundant noncollagenous bone protein, is contained in and secreted from human platelets. In this study, the distribution of osteonectin both in the supernatant and on the platelet surface after activation was measured by fluid-phase and solid-phase radioimmunoassay, respectively. Total cellular osteonectin was determined by RIA of guanidinium chloride extracted platelets and ranged from 0.65 to 2.2 micrograms/10(8) platelets or 135,000 to 457,000 molecules/platelet. Platelets treated with varying concentrations of collagen and thrombin r

APA, Harvard, Vancouver, ISO, and other styles

6

Jurasz, Paul, David Alonso, Susana Castro-Blanco, Ferid Murad, and Marek W. Radomski. "Generation and role of angiostatin in human platelets." Blood 102, no. 9 (2003): 3217–23. http://dx.doi.org/10.1182/blood-2003-02-0378.

Full text

Abstract:

AbstractPlatelets regulate new blood vessel growth, because they contain a number of angiogenesis promoters and inhibitors. Additionally, platelets contain matrix metalloproteinases (MMPs), which when released mediate platelet adhesion and aggregation, and plasminogen, a fibrinolytic system enzyme that serves to limit blood clot formation. Enzymatic cleavage of plasminogen by MMPs generates angiostatin, an angiogenesis inhibitor. Therefore, we examined whether platelets generate angiostatin during aggregation in vitro. Platelets were isolated from healthy human donors and then aggregated with

APA, Harvard, Vancouver, ISO, and other styles

7

Spertini, Olivier, Jacques Hauert, and Fedor Bachmann. "Reaction of Acetaldehyde with Human Platelets." Thrombosis and Haemostasis 67, no. 01 (1992): 126–30. http://dx.doi.org/10.1055/s-0038-1648393.

Full text

Abstract:

SummaryPlatelet function defects observed in chronic alcoholics are not wholly explained by the inhibitory action of ethanol on platelet aggregation; they are not completely reproduced either in vivo by short-term ethanol perfusion into volunteers or in vitro by the addition of ethanol to platelet-rich plasma. As acetaldehyde (AcH) binds to many proteins and impairs cellular activities, we investigated the effect of this early degradation product of ethanol on platelets. AcH formed adducts with human platelets at neutral pH at 37° C which were stable to extensive washing, trichloracetic acid h

APA, Harvard, Vancouver, ISO, and other styles

8

Malmgren, R., T. Thorsen, R. T. Lie, and H. Holmsen. "Microbubble-Induced Serotonin Secretion in Human Platelets." Thrombosis and Haemostasis 65, no. 04 (1991): 399–402. http://dx.doi.org/10.1055/s-0038-1648160.

Full text

Abstract:

SummaryThe effect of nitrogen (N2) microbubbles on platelets resembles that of common platelet agonists with respect to aggregation (Thorsen T et al., Undersea Biomed Res 1986; 13:289-303). In the present study we examined the effect of microbubbles on platelet secretion of preloaded 14C-serotonin. We demonstrate that stirring of platelet-rich plasma with N2-microbubbles causes a loss of single platelets that is associated with secretion. However, secretion did not increase above baseline values until after 20 min of microbubble exposure, when platelet aggregation had reached 40%. After that t

APA, Harvard, Vancouver, ISO, and other styles

9

Fong, Karen P., Colin Barry, Anh N. Tran, et al. "Deciphering the human platelet sheddome." Blood 117, no. 1 (2011): e15-e26. http://dx.doi.org/10.1182/blood-2010-05-283838.

Full text

Abstract:

Abstract Activated platelets shed surface proteins, potentially modifying platelet function as well as providing a source of bioactive fragments. Previous studies have identified several constituents of the platelet sheddome, but the full extent of shedding is unknown. Here we have taken a global approach, analyzing protein fragments in the supernate of activated platelets using mass spectroscopy and looking for proteins originating from platelet membranes. After removing plasma proteins and microparticles, 1048 proteins were identified, including 69 membrane proteins. Nearly all of the membra

APA, Harvard, Vancouver, ISO, and other styles

10

Takahashi, Hoyu, and Akira Shibata. "Agglutination of Platelet-Type von Willebrand’s Disease Platelets by Bovine von Willebrand Factor." Thrombosis and Haemostasis 53, no. 02 (1985): 204–7. http://dx.doi.org/10.1055/s-0038-1661274.

Full text

Abstract:

SummaryIt has been shown that platelets from patients with platelet- type von Willebrand’s disease (vWD) agglutinate upon the addition of human von Willebrand factor (vWF) in the absence of ristocetin or botrocetin, suggesting that platelet membrane receptors for human vWF is abnormal. The present work reports the platelet agglutinability on stimulation with bovine vWF in platelet-type vWD. Platelets in patient platelet-rich plasma or washed platelet suspensions and patient platelets treated with formalin agglutinated in the presence of markedly lower concentrations of bovine vWF than those re

APA, Harvard, Vancouver, ISO, and other styles

More sources

Dissertations / Theses on the topic "Human platelet"

1

Bunescu, Andreia. "Cellular markers indicating activation of the hemostatic system : studies on platelets and leukocytes in peripheral human blood /." Stockholm, 2003. http://diss.kib.ki.se/2003/91-7349-759-2/.

Full text

APA, Harvard, Vancouver, ISO, and other styles

2

Rolf, Michael George. "P2X₁ receptors and human platelet function." Thesis, University of Cambridge, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.621241.

Full text

APA, Harvard, Vancouver, ISO, and other styles

3

Sato, Masami. "Effects of barbiturates on human platelet aggregation." Kyoto University, 2003. http://hdl.handle.net/2433/148488.

Full text

APA, Harvard, Vancouver, ISO, and other styles

4

Zijenah, Lynn Sodai. "The platelet-reactivity of human collagens I and III : investigation of platelet-reactive sites in the human collagen molecule." Thesis, University of Cambridge, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.359782.

Full text

APA, Harvard, Vancouver, ISO, and other styles

5

Bienz, Denise Edith. "Human blood platelets : the role of glycoproteins in the platelet interaction with thrombin and collagen /." [S.l.] : [s.n.], 1988. http://www.ub.unibe.ch/content/bibliotheken_sammlungen/sondersammlungen/dissen_bestellformular/index_ger.html.

Full text

APA, Harvard, Vancouver, ISO, and other styles

6

Scott, Nigel T. "Investigations on human factor 8 and platelet function." Thesis, University of East London, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.353257.

Full text

APA, Harvard, Vancouver, ISO, and other styles

7

Bouwmans, Eva Lamberta Antonia. "Human platelet antigen-1a presentation and antibody generation." Thesis, University of Cambridge, 2012. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.610311.

Full text

APA, Harvard, Vancouver, ISO, and other styles

8

Simpson, Craig J. "Studies on the structure of human platelet phosphofructokinase." Thesis, University of Edinburgh, 1991. http://hdl.handle.net/1842/20189.

Full text

Abstract:

Phosphofructokinase (ATP: D-fructose 6-phosphate 1-transferase, EC 2.7.1.11) catalyses the phosphorylation of fructose 6-phosphate to fructose 1,6-bisphosphate, and is a key regulatory enzyme in glycolysis. Sequence conservation between mammalian PFK and PFK from <i>E.coli, B.stearothermophilus</i> and <i>S.citri</i>, and between the amino and carboxyl halves of the mammalian enzymes suggests that mammalian PFK has evolved from a prokaryotic progenitor by a process of gene duplication and fusion. The aim of this project was to obtain detailed structural information describing PFK from humans a

APA, Harvard, Vancouver, ISO, and other styles

9

Baker, Jennifer Mary. "The effect of extracellular pH on human platelet metabolism." Thesis, University of Birmingham, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.368422.

Full text

APA, Harvard, Vancouver, ISO, and other styles

10

Hall, David A. "The biochemical pharmacology of the human platelet ADP receptor." Thesis, University of Surrey, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.385201.

Full text

APA, Harvard, Vancouver, ISO, and other styles

More sources

Books on the topic "Human platelet"

1

1946-, Barnes Peter J., Page C. P, and Henson P. M. 1940-, eds. Platelet activating factor and human disease. Blackwell Scientific, 1989.

Find full text

APA, Harvard, Vancouver, ISO, and other styles

2

Duttaroy, Asim K. Nutraceuticals and Human Blood Platelet Function. John Wiley & Sons, Ltd, 2018. http://dx.doi.org/10.1002/9781119375913.

Full text

APA, Harvard, Vancouver, ISO, and other styles

3

Scott, N. J. Investigations on human factor VIII and platelet function. North East London Polytechnic, 1985.

Find full text

APA, Harvard, Vancouver, ISO, and other styles

4

Baker, Jennifer Mary. The effect of extracellular pH on human platelet metabolism. University of Birmingham, 2000.

Find full text

APA, Harvard, Vancouver, ISO, and other styles

5

European Thrombosis Research Organisation. Workshop. Monoclonal antibodies and human blood platelets: Proceedings of the European Thrombosis Research Organisation Workshop, under the patronage of the Institut national de la santé et de la recherche médicale, held in Lyon (France), 26-27 September 1985. Edited by McGregor John Louis and Institut national de la santé et de la recherche médicale (France). Elsevier Science Publishers, 1986.

Find full text

APA, Harvard, Vancouver, ISO, and other styles

6

Stott, Andrew James. Studies on human blood platelets. typescript, 1990.

Find full text

APA, Harvard, Vancouver, ISO, and other styles

7

C, Somogyi J., Renaud Serge, and Astier-Dumas M, eds. Emerging problems in human nutrition. Karger, 1987.

Find full text

APA, Harvard, Vancouver, ISO, and other styles

8

L, Gordon J., ed. Vascular endothelium: Interactions with circulating cells. Elsevier, 1991.

Find full text

APA, Harvard, Vancouver, ISO, and other styles

9

Bjorn, Neu, and Meiselman Herbert J, eds. Red blood cell aggregation. CRC Press, 2012.

Find full text

APA, Harvard, Vancouver, ISO, and other styles

10

1946-, Barnes P. J., Page Clive P, and Henson P. M. 1940-, eds. Plateletactivating factor and human disease. Blackwell Scientific, 1989.

Find full text

APA, Harvard, Vancouver, ISO, and other styles

More sources

Book chapters on the topic "Human platelet"

1

Savage, B., C. S. Hunter, L. A. Harker, and S. R. Hanson. "Origins and Significance of Platelet Heterogeneity in a Non-human Primate Model." In Platelet Heterogeneity. Springer London, 1990. http://dx.doi.org/10.1007/978-1-4471-1763-6_5.

Full text

APA, Harvard, Vancouver, ISO, and other styles

2

Morgenstern, E. "Human Platelet Morphology/Ultrastructure." In Platelets and Their Factors. Springer Berlin Heidelberg, 1997. http://dx.doi.org/10.1007/978-3-642-60639-7_2.

Full text

APA, Harvard, Vancouver, ISO, and other styles

3

Impens, Francis, Kenny Helsens, Niklaas Colaert, Lennart Martens, Joël Vandekerckhove, and Kris Gevaert. "N-Terminal Combined Fractional Diagonal Chromatographic (COFRADIC) Analysis of the Human Platelet Proteome." In Platelet Proteomics. John Wiley & Sons, Inc., 2011. http://dx.doi.org/10.1002/9780470940297.ch8.

Full text

APA, Harvard, Vancouver, ISO, and other styles

4

Lechi, A., C. Lechi, C. Lauciello, et al. "Platelet Abnormalities in Human Hypertension." In Cellular Aspects of Hypertension. Springer Berlin Heidelberg, 1991. http://dx.doi.org/10.1007/978-3-662-00983-3_23.

Full text

APA, Harvard, Vancouver, ISO, and other styles

5

Barnett, D. B., S. S. Swart, S. R. Nahorski, and N. Cook. "Characterisation of Human Platelet Adrenoceptors." In Advances in Experimental Medicine and Biology. Springer US, 1985. http://dx.doi.org/10.1007/978-1-4615-9442-0_8.

Full text

APA, Harvard, Vancouver, ISO, and other styles

6

Rox, Jutta M., Jens Müller, and Bernd Pötzsch. "PCR-Based Amplification of Platelet mRNA Sequences Obtained From Small-Scale Platelet Samples." In DNA and RNA Profiling in Human Blood. Humana Press, 2009. http://dx.doi.org/10.1007/978-1-59745-553-4_18.

Full text

APA, Harvard, Vancouver, ISO, and other styles

7

White, James G. "Structural Defects in Inherited and Giant Platelet Disorders." In Advances in Human Genetics. Springer US, 1990. http://dx.doi.org/10.1007/978-1-4757-9065-8_3.

Full text

APA, Harvard, Vancouver, ISO, and other styles

8

Jamieson, G. A., Narendra N. Tandon, and Nicholas J. Greco. "Human Platelet Thrombin Receptors and the Two Receptor Model for Platelet Activation." In Handbook of Platelet Physiology and Pharmacology. Springer US, 1999. http://dx.doi.org/10.1007/978-1-4615-5049-5_2.

Full text

APA, Harvard, Vancouver, ISO, and other styles

9

Schiffer, C. A. "Single Donor Platelet Transfusion." In Modern Trends in Human Leukemia VI New Results in Clinical and Biological Research Including Pediatric Oncology. Springer Berlin Heidelberg, 1985. http://dx.doi.org/10.1007/978-3-642-70385-0_29.

Full text

APA, Harvard, Vancouver, ISO, and other styles

10

Travers, Jeffrey B. "Platelet-Activating Factor as an Effector for Environmental Stressors." In Lipid Signaling in Human Diseases. Springer International Publishing, 2019. http://dx.doi.org/10.1007/164_2019_218.

Full text

APA, Harvard, Vancouver, ISO, and other styles

Conference papers on the topic "Human platelet"

1

Bryckaert, M. C., A. Wasteson, G. Tobelem, F. Rendu, and J. P. Caen. "PLATELET DERIVED GROWTH FACTOR (PDGF) BINDS TO HUMAN PLATELETS AND MODULATES PLATELET ACTIVATION." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643493.

Full text

Abstract:

PDGF which is released during platelet activation like the other ∝ granule components (fibrinogen, F VIII/vWF, PF4) could bind to platelet membrane Following this hypothesis, we have studied the binding of 125I pure human PDGF to washed human platelets activated by collagen. This binding was specific and time dependent and reached a plateau with 20 μg/ml of collagen. With 200 fold excess of unlabeled PDGF, the binding of 125I-PDGF decreased progressively to 10 .whereas unlabeled Epidermal Growth Factor did not compete with 125I-PDGF. Saturation curve and scatchard analysis have shown one class

APA, Harvard, Vancouver, ISO, and other styles

2

Struk, A., A. Prins, M. C. L. Schaap, J. W. ten Cate, and H. van den Bosch. "SYNTHESIS OF PLATELET ACTIVATING FACTOR BY HUMAN BLOOD PLATELETS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643486.

Full text

Abstract:

Synthesis of platelet activating factor (PAF) by human blood platelets is a controversial issue. Whereas some groups have reported the synthesis, induced by thrombin, collagen or Ca2--ionophore Azsio?, others were unable to obtain for instance the thrombin-induced PAF synthesis. Also, synthesis of only up to 6 pMoles PAF/10 platelets has been reported, but leucocytes may synthesize up to 6000 pMoles PAF/10 cells. Only an 0.1% leucocyte contamination would thereby explain the “ platelet PAF synthesis” . We therefore optimized the PAF synthesis by human blood platelets and leucocytes, induced by

APA, Harvard, Vancouver, ISO, and other styles

3

Pintigny, D., L. J. Wautier, B. Andreassian, and P. J. Caen. "PLATELET ADHESION TO HUMAN AORTIC FRAGMENTS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643549.

Full text

Abstract:

Due to the fact that the adhesion of platelet aggregates to microdamaged sites in the vascular endothelium holds a critical step in the pathogenesis of thrombotic and sclerotic plaques, we investigated the adhesion of platelets to arteritic vessel wall. Aortic samples were obtained from patients with peripheral vascular disease who required a prosthetic replacement in their aortic bifurcation. Aortic fragments were collected into buffer and tested within 24 hours after collection. The adhesion of normal platelets to the vessel fragment and the prostacyclin (PGI2) production were tested in 11 c

APA, Harvard, Vancouver, ISO, and other styles

4

Cohen, I., D. Burk, R. J. Fullertone, A. Veis, and D. Green. "NONENZYMATIC GLYCATI0N OF HUMAN BLOOD PLATELET PROTEINS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644491.

Full text

Abstract:

Atherothrombotic events are common in diabetics, and enhanced platelet function is thought to be partly responsible. Since excessive glycation occurs in many proteins of diabetic subjects, we decided to evaluate glycation of diabetic platelet proteins, and especially those proteins known to be involved in platelet aggregation. We believe this is the first report of nonenzy-matic glycation of platelet proteins from patients with poorly-controlled diabetes mellitus. Overall glycation was assessed by the extent of incorporation of [3H]BH4 into fructosyl lysine separated from whole platelet protei

APA, Harvard, Vancouver, ISO, and other styles

5

Lian, E. C. Y., and F. A. Siddigui. "BINDING OF 37-DKa PLATELET AGGLUTINATING PROTEIN TO HUMAN PLATELETS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643976.

Full text

Abstract:

We have previously reported the purification of a 37-KDa platelet agglutinating protein (PAP p37) from the plasma of a patient with thrombotic thrombocytopenic purpura. using 125I-labeled p37, the properties of its binding to platelets were studied. The binding of p37 to washed human platelets from 4 normal subjects and two TTP patients after recovery was specific, concentration dependent and saturable. The Scatchard analysis revealed that the binding sites for p37 was about 100,000 per platelet with a dissociation constant of 48 × 10−9 M. The binding of p37 to erythrocytes was very little and

APA, Harvard, Vancouver, ISO, and other styles

6

PEERSCHKE, E. IB, and B. Ghebrehiwet. "CHARACTERIZATION OF HUMAN PLATELET ClQ BINDING SITES." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643503.

Full text

Abstract:

We have recently shown that platelets possess specific binding sites for Clq, a subcomponent of the first component of complement, Cl, and that occupancy of these receptor sites correlates with the previously described inhibitory effect of Clq on collagen-induced platelet aggregation. To further characterize platelet Clq receptors, washed platelets were solubilized in 5 mM sodium phosphate buffer, pH 7.5 containing 10 mM EDTA, 150 mM NaCl, 10 mM EACA, 0.5 mM PMSF, and 1% Triton X-100. After dialysis against 5 mM phosphate buffer pH 7.5 containing 10 mM EDTA, 20 mM NaCl, 10 mM EACA,0.5 mM PMSF

APA, Harvard, Vancouver, ISO, and other styles

7

Chen, W. J., Z. Chen, and C. X. Bao. "HIP2: A NEW MONOCLONAL ANTI-HUMAN PLATELET ANTIBODY WITH STIMULANT FUNCTION." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643505.

Full text

Abstract:

A monoclonal anti-human platelet antibody(MoAb), HIP2 (IgG3) which induced irrevesible aggregation of platelet in association with the release of serotonin and thromboxane B2 formation is described. Indirect immunofluorescence assay (IFS) showed that the antibody binded to platelets and megakryocytes, and gave a weak reaction with aortic, liver and capillary endothelial cells. Electrophoresis of radiolabelled antigen showed that HIP2 recognized platelet membrane glycoprotein lib (130KD). The purified HIP2 MoAb induced aggregation with normal PRP, not with thrombasthenia platelets, formalin-fix

APA, Harvard, Vancouver, ISO, and other styles

8

Matsuno, K., F. Katabami, M. Koyama, et al. "PLATELET-ACTIVATING FACTOR (PAF)-INDUCED INTRACELLULAR Ca MOBILIZATION IN HUMAN PLATELETS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643483.

Full text

Abstract:

PAF-induced intracellular Ca2+ mobilization and platelet aggregation were investigated in human platelets. Cytosolic free Ca2+ concentration ([Ca2+]cyt) was measured by using fluorescent 45Ca2+ probe quin2 and fura-2, and photoprotein aequorin. Ca2+ uptake was measured after stimulation by PAF. Platelet aggregation was studied by recording the change in light transmission with platelet rich plasma (PRP) or washed platelet suspension (WPS).These three Ca2+ -indicators could determine the elevation of [Ca2+ ]cyt that was stimulated by PAF in the presence of extra- cellular Ca2+ (quin2 method: 98

APA, Harvard, Vancouver, ISO, and other styles

9

Bauman, J. E., J. H. Joist, G. Vogler, and S. P. Sutera. "HIGH SUSCEPTIBILITY OF RABBIT, DOG, AND PIG PLATELETS TO SHEAR-INDUCED INJURY." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1642846.

Full text

Abstract:

In an attempt to develop an animal model for the study of the effects of fluid shear stress on platelet in vivo survival we examined the effects of repetitive short-duration (5 sec) and continuous prolonged (5 min) shear exposure in a cone-plate viscometer and Couette rotational viscometer on platelets (in citrated platelet-rich plasma) from humans, rabbits, dogs, and pigs. Comparable platelet aggregation (PAG = loss of single platelets) (18-64%) was observed with platelets from all species, associated with dense granule release, as a function of shear stress amplitude (25-50 dyn/cm2) under th

APA, Harvard, Vancouver, ISO, and other styles

10

Jansen, J. W. C. M. "EFFECTS OF INHIBITORS ON COLLAGEN INDUCED PLATELET AGGREGATION IN SIX DIFFERENT SPECIES." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643445.

Full text

Abstract:

One approach to the development of antithrombotics is inhibition of platelet aggregation. The pharmacological approach often used is to test compounds on collagen induced platelet aggregation measured in platelet rich plasma. Therefore we have compared inhibitors with different mechanism of action on aggregation of platelets from six different species commonly used in pharmacological studies. Aggregation was induced with submaximal amounts of collagen (Hormone Chemie).Inhibitors of the cyclooxygenase system, aspirin and indomethacin, were very potent in inhibiting aggregation of platelets from

APA, Harvard, Vancouver, ISO, and other styles

Reports on the topic "Human platelet"

1

Michelson, A. D., H. MacGregor, A. Kestin, M. R. Barnard, and M. J. Rohrer. Reversible Hypothermia-Induced Inhibition of Human Platelet Activation in Whole Blood in Vitro and in Vivo. Defense Technical Information Center, 1992. http://dx.doi.org/10.21236/ada360296.

Full text

APA, Harvard, Vancouver, ISO, and other styles

2

Martín-López, María, Cristina Rosell-Valle, Blanca Arribas-Arribas, et al. Evaluation of cryopreservation solutions based on human platelet lysate for bioengineered bissues aimed for advanced therapy treatments. Peeref, 2023. http://dx.doi.org/10.54985/peeref.2306p4363615.

Full text

APA, Harvard, Vancouver, ISO, and other styles

3

Petrova, I. V., O. A. Trubacheva, O. S. Mangataeva, T. E. Suslova, I. V. Kovalev, and S. V. Gusakova. INFLUENCE OF HYDROGEN SULFIDE ON COLLAGEN-INDUCED AGGREGATION OF HUMAN PLATELETS. DOI CODE, 2015. http://dx.doi.org/10.18411/doicode-2023.141.

Full text

APA, Harvard, Vancouver, ISO, and other styles

4

Zuckerman, Kenneth S. Reparative Medicine: Production of Erythrocytes & Platelets from Human Embryonic Stem Cells. Defense Technical Information Center, 2012. http://dx.doi.org/10.21236/ada566171.

Full text

APA, Harvard, Vancouver, ISO, and other styles

5

Lawanprasert, Somsong, Chaiyo Chaichantipyuth, Supatra Srichairat, Nuansri Niwattisaiwong, and Laddawal Phivthong-ngam. Subchronic exposure of Pueraria mirifica in normal - and high cholesterol diet fed rats : influence on hepatic cytochrome P450, lipid profile and toxicity. Chulalongkorn University, 2004. https://doi.org/10.58837/chula.res.2004.28.

Full text

Abstract:

Pueraria mirifica airy shaw and suvatabandhu, know locally as Kwao Keur, is a plant in family Leguminosae. In this study, effects of P.mirifica on hepatic cytochrome P450 (CYP), serum lipid profile and subchronic toxicity were investigated in male Wistar rats. Rats were randomly divided into four treatment groups as following: normal diet-fed group; normal diet-fed supplemented with P.mirifica group; high cholesterol diet-fed group; high cholesterol diet-fed supplemented with P.mirifica group. Each group comprised 10 rats. P.mirifica was administered orally at a dosage of 100 mg/kg/day for 90

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!